No. | Citations | ECcit | RCR | ECRCR | Title | Authors | Journal | Year | PMID | Article(?) |
---|---|---|---|---|---|---|---|---|---|---|
1 | 165492 | 165492.0 | 0.0 | 0.0 | Cleavage of structural proteins during the assembly of the head of bacteriophage T4. | U K Laemmli | Nature | 1970 | 5432063 | Yes |
2 | 130332 | 130332.0 | 0.0 | 0.0 | A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. | M M Bradford | Anal Biochem | 1976 | 942051 | Yes |
3 | 194694 | 48673.5 | 0.0 | 0.0 | Protein measurement with the Folin phenol reagent. | O H LOWRY, N J ROSEBROUGH, A L FARR, R J RANDALL | J Biol Chem | 1951 | 14907713 | Yes |
4 | 85726 | 42863.0 | 2400.69 | 1200.3 | Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. | K J Livak, T D Schmittgen | Methods | 2001 | 11846609 | Yes |
5 | 39803 | 39803.0 | 1507.92 | 1507.9 | A short history of SHELX. | George M Sheldrick | Acta Crystallogr A | 2008 | 18156677 | Yes |
6 | 27343 | 27343.0 | 1119.59 | 1119.6 | Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. | T Mosmann | J Immunol Methods | 1983 | 6606682 | Yes |
7 | 23236 | 23236.0 | 0.0 | 0.0 | Detection of specific sequences among DNA fragments separated by gel electrophoresis. | E M Southern | J Mol Biol | 1975 | 1195397 | Yes |
8 | 45367 | 22683.5 | 1809.82 | 904.9 | Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. | P Chomczynski, N Sacchi | Anal Biochem | 1987 | 2440339 | Yes |
9 | 22544 | 22544.0 | 540.7 | 540.7 | MicroRNAs: genomics, biogenesis, mechanism, and function. | David P Bartel | Cell | 2004 | 14744438 | No |
10 | 22304 | 22304.0 | 0.0 | 0.0 | The assessment and analysis of handedness: the Edinburgh inventory. | R C Oldfield | Neuropsychologia | 1971 | 5146491 | Yes |
11 | 19669 | 19669.0 | 502.72 | 502.7 | A new mathematical model for relative quantification in real-time RT-PCR. | M W Pfaffl | Nucleic Acids Res | 2001 | 11328886 | Yes |
12 | 19523 | 19523.0 | 510.07 | 510.1 | MUSCLE: multiple sequence alignment with high accuracy and high throughput. | Robert C Edgar | Nucleic Acids Res | 2004 | 15034147 | Yes |
13 | 17845 | 17845.0 | 0.0 | 0.0 | A rating scale for depression. | M HAMILTON | J Neurol Neurosurg Psychiatry | 1960 | 14399272 | Yes |
14 | 48733 | 16244.3 | 0.0 | 0.0 | "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. | M F Folstein, S E Folstein, P R McHugh | J Psychiatr Res | 1975 | 1202204 | Yes |
15 | 31709 | 15854.5 | 1167.41 | 583.7 | The neighbor-joining method: a new method for reconstructing phylogenetic trees. | N Saitou, M Nei | Mol Biol Evol | 1987 | 3447015 | Yes |
16 | 45139 | 15046.3 | 0.0 | 0.0 | DNA sequencing with chain-terminating inhibitors. | F Sanger, S Nicklen, A R Coulson | Proc Natl Acad Sci U S A | 1977 | 271968 | Yes |
17 | 28672 | 14336.0 | 1096.37 | 548.2 | Hallmarks of cancer: the next generation. | Douglas Hanahan, Robert A Weinberg | Cell | 2011 | 21376230 | No |
18 | 14326 | 14326.0 | 527.91 | 527.9 | CONFIDENCE LIMITS ON PHYLOGENIES: AN APPROACH USING THE BOOTSTRAP. | Joseph Felsenstein | Evolution | 1985 | 28561359 | Yes |
19 | 14298 | 14298.0 | 0.0 | 0.0 | The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. | E S REYNOLDS | J Cell Biol | 1963 | 13986422 | Yes |
20 | 13788 | 13788.0 | 408.44 | 408.4 | Atherosclerosis--an inflammatory disease. | R Ross | N Engl J Med | 1999 | 9887164 | No |
21 | 13643 | 13643.0 | 0.0 | 0.0 | Tissue sulfhydryl groups. | G L ELLMAN | Arch Biochem Biophys | 1959 | 13650640 | Yes |
22 | 27272 | 13636.0 | 1618.12 | 809.1 | Statistical methods for assessing agreement between two methods of clinical measurement. | J M Bland, D G Altman | Lancet | 1986 | 2868172 | Yes |
23 | 13248 | 13248.0 | 580.09 | 580.1 | A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences. | M Kimura | J Mol Evol | 1980 | 7463489 | Yes |
24 | 12788 | 12788.0 | 559.35 | 559.4 | Density-functional exchange-energy approximation with correct asymptotic behavior. | Becke | Phys Rev A Gen Phys | 1988 | 9900728 | Yes |
25 | 38149 | 12716.3 | 1271.72 | 423.9 | CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. | J D Thompson, D G Higgins, T J Gibson | Nucleic Acids Res | 1994 | 7984417 | Yes |
26 | 25386 | 12693.0 | 0.0 | 0.0 | The measurement of observer agreement for categorical data. | J R Landis, G G Koch | Biometrics | 1977 | 843571 | Yes |
27 | 12290 | 12290.0 | 352.33 | 352.3 | MicroRNAs: target recognition and regulatory functions. | David P Bartel | Cell | 2009 | 19167326 | No |
28 | 35558 | 11852.7 | 0.0 | 0.0 | Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. | H Towbin, T Staehelin, J Gordon | Proc Natl Acad Sci U S A | 1979 | 388439 | Yes |
29 | 11744 | 11744.0 | 0.0 | 0.0 | High resolution two-dimensional electrophoresis of proteins. | P H O'Farrell | J Biol Chem | 1975 | 236308 | Yes |
30 | 22777 | 11388.5 | 0.0 | 0.0 | A rapid method of total lipid extraction and purification. | E G BLIGH, W J DYER | Can J Biochem Physiol | 1959 | 13671378 | Yes |
31 | 22403 | 11201.5 | 1006.64 | 503.3 | Meta-analysis in clinical trials. | R DerSimonian, N Laird | Control Clin Trials | 1986 | 3802833 | Yes |
32 | 10854 | 10854.0 | 561.53 | 561.5 | A power primer. | J Cohen | Psychol Bull | 1992 | 19565683 | Yes |
33 | 21566 | 10783.0 | 1077.53 | 538.8 | The hospital anxiety and depression scale. | A S Zigmond, R P Snaith | Acta Psychiatr Scand | 1983 | 6880820 | Yes |
34 | 10593 | 10593.0 | 0.0 | 0.0 | DISC ELECTROPHORESIS. II. METHOD AND APPLICATION TO HUMAN SERUM PROTEINS. | B J DAVIS | Ann N Y Acad Sci | 1964 | 14240539 | Yes |
35 | 30500 | 10166.7 | 0.0 | 0.0 | A simple method for the isolation and purification of total lipides from animal tissues. | J FOLCH, M LEES, G H SLOANE STANLEY | J Biol Chem | 1957 | 13428781 | Yes |
36 | 10164 | 10164.0 | 487.44 | 487.4 | Catalase in vitro. | H Aebi | Methods Enzymol | 1984 | 6727660 | Yes |
37 | 9989 | 9989.0 | 323.89 | 323.9 | Projector augmented-wave method. | Blöchl | Phys Rev B Condens Matter | 1994 | 9976227 | Yes |
38 | 9986 | 9986.0 | 0.0 | 0.0 | A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. | K BURTON | Biochem J | 1956 | 13293190 | Yes |
39 | 19422 | 9711.0 | 450.9 | 225.4 | Coot: model-building tools for molecular graphics. | Paul Emsley, Kevin Cowtan | Acta Crystallogr D Biol Crystallogr | 2004 | 15572765 | Yes |
40 | 9654 | 9654.0 | 562.12 | 562.1 | RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies. | Alexandros Stamatakis | Bioinformatics | 2014 | 24451623 | Yes |
41 | 18881 | 9440.5 | 1010.11 | 505.1 | The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. | J E Ware, C D Sherbourne | Med Care | 1992 | 1593914 | Yes |
42 | 9357 | 9357.0 | 422.97 | 423.0 | Structure validation in chemical crystallography. | Anthony L Spek | Acta Crystallogr D Biol Crystallogr | 2009 | 19171970 | Yes |
43 | 46106 | 9221.2 | 1536.05 | 307.2 | Basic local alignment search tool. | S F Altschul, W Gish, W Miller, E W Myers, D J Lipman | J Mol Biol | 1990 | 2231712 | Yes |
44 | 9186 | 9186.0 | 0.0 | 0.0 | The genetics of Caenorhabditis elegans. | S Brenner | Genetics | 1974 | 4366476 | Yes |
45 | 18211 | 9105.5 | 520.93 | 260.5 | Fast and accurate short read alignment with Burrows-Wheeler transform. | Heng Li, Richard Durbin | Bioinformatics | 2009 | 19451168 | Yes |
46 | 17856 | 8928.0 | 428.41 | 214.2 | [20] Processing of X-ray diffraction data collected in oscillation mode. | Zbyszek Otwinowski, Wladek Minor | Methods Enzymol | 1997 | 27799103 | Yes |
47 | 8849 | 8849.0 | 344.85 | 344.9 | Search and clustering orders of magnitude faster than BLAST. | Robert C Edgar | Bioinformatics | 2010 | 20709691 | Yes |
48 | 25982 | 8660.7 | 909.63 | 303.2 | Generalized Gradient Approximation Made Simple. | Perdew, Burke, Ernzerhof | Phys Rev Lett | 1996 | 10062328 | Yes |
49 | 8502 | 8502.0 | 261.69 | 261.7 | XDS. | Wolfgang Kabsch | Acta Crystallogr D Biol Crystallogr | 2010 | 20124692 | Yes |
50 | 8474 | 8474.0 | 0.0 | 0.0 | Phosphorus assay in column chromatography. | G R BARTLETT | J Biol Chem | 1959 | 13641241 | Yes |
51 | 8423 | 8423.0 | 281.34 | 281.3 | The Psychophysics Toolbox. | D H Brainard | Spat Vis | 1997 | 9176952 | Yes |
52 | 8394 | 8394.0 | 344.76 | 344.8 | Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). | J F Kurtzke | Neurology | 1983 | 6685237 | Yes |
53 | 15954 | 7977.0 | 621.8 | 310.9 | Fast gapped-read alignment with Bowtie 2. | Ben Langmead, Steven L Salzberg | Nat Methods | 2012 | 22388286 | Yes |
54 | 7896 | 7896.0 | 183.24 | 183.2 | Mfold web server for nucleic acid folding and hybridization prediction. | Michael Zuker | Nucleic Acids Res | 2003 | 12824337 | Yes |
55 | 7858 | 7858.0 | 172.81 | 172.8 | Linear models and empirical bayes methods for assessing differential expression in microarray experiments. | Gordon K Smyth | Stat Appl Genet Mol Biol | 2004 | 16646809 | Yes |
56 | 15706 | 7853.0 | 573.98 | 287.0 | A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. | A P Feinberg, B Vogelstein | Anal Biochem | 1983 | 6312838 | Yes |
57 | 7853 | 7853.0 | 228.62 | 228.6 | RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. | Alexandros Stamatakis | Bioinformatics | 2006 | 16928733 | Yes |
58 | 23537 | 7845.7 | 1057.8 | 352.6 | Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density. | Lee, Yang, Parr | Phys Rev B Condens Matter | 1988 | 9944570 | Yes |
59 | 7783 | 7783.0 | 363.06 | 363.1 | A new method for measuring daytime sleepiness: the Epworth sleepiness scale. | M W Johns | Sleep | 1991 | 1798888 | Yes |
60 | 15489 | 7744.5 | 362.72 | 181.4 | The hallmarks of cancer. | D Hanahan, R A Weinberg | Cell | 2000 | 10647931 | No |
61 | 7709 | 7709.0 | 264.41 | 264.4 | Studies on transformation of Escherichia coli with plasmids. | D Hanahan | J Mol Biol | 1983 | 6345791 | Yes |
62 | 15228 | 7614.0 | 491.05 | 245.5 | Quantifying heterogeneity in a meta-analysis. | Julian P T Higgins, Simon G Thompson | Stat Med | 2002 | 12111919 | Yes |
63 | 7598 | 7598.0 | 0.0 | 0.0 | Self-efficacy: toward a unifying theory of behavioral change. | A Bandura | Psychol Rev | 1977 | 847061 | Yes |
64 | 7490 | 7490.0 | 252.64 | 252.6 | Evolutionary trees from DNA sequences: a maximum likelihood approach. | J Felsenstein | J Mol Evol | 1981 | 7288891 | Yes |
65 | 14835 | 7417.5 | 791.36 | 395.7 | The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. | R M Baron, D A Kenny | J Pers Soc Psychol | 1986 | 3806354 | Yes |
66 | 7279 | 7279.0 | 253.03 | 253.0 | Vitamin D deficiency. | Michael F Holick | N Engl J Med | 2007 | 17634462 | No |
67 | 14544 | 7272.0 | 493.19 | 246.6 | A simple method for displaying the hydropathic character of a protein. | J Kyte, R F Doolittle | J Mol Biol | 1982 | 7108955 | Yes |
68 | 7213 | 7213.0 | 259.73 | 259.7 | The pathogenesis of atherosclerosis: a perspective for the 1990s. | R Ross | Nature | 1993 | 8479518 | No |
69 | 7063 | 7063.0 | 161.09 | 161.1 | The functions of animal microRNAs. | Victor Ambros | Nature | 2004 | 15372042 | No |
70 | 6961 | 6961.0 | 291.64 | 291.6 | Banting lecture 1988. Role of insulin resistance in human disease. | G M Reaven | Diabetes | 1988 | 3056758 | No |
71 | 6933 | 6933.0 | 0.0 | 0.0 | Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. | A Böyum | Scand J Clin Lab Invest Suppl | 1968 | 4179068 | Yes |
72 | 6904 | 6904.0 | 0.0 | 0.0 | On the origin of cancer cells. | O WARBURG | Science | 1956 | 13298683 | Yes |
73 | 27584 | 6896.0 | 946.21 | 236.6 | Measuring inconsistency in meta-analyses. | Julian P T Higgins, Simon G Thompson, Jonathan J Deeks, Douglas G Altman | BMJ | 2003 | 12958120 | No |
74 | 6892 | 6892.0 | 0.0 | 0.0 | Improvements in epoxy resin embedding methods. | J H LUFT | J Biophys Biochem Cytol | 1961 | 13764136 | Yes |
75 | 13504 | 6752.0 | 327.75 | 163.9 | Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. | Kazutoshi Takahashi, Shinya Yamanaka | Cell | 2006 | 16904174 | Yes |
76 | 6701 | 6701.0 | 218.83 | 218.8 | Integrins: versatility, modulation, and signaling in cell adhesion. | R O Hynes | Cell | 1992 | 1555235 | No |
77 | 6639 | 6639.0 | 538.81 | 538.8 | Crystal structure refinement with SHELXL. | George M Sheldrick | Acta Crystallogr C Struct Chem | 2015 | 25567568 | Yes |
78 | 6558 | 6558.0 | 367.93 | 367.9 | Psychophysical bases of perceived exertion. | G A Borg | Med Sci Sports Exerc | 1982 | 7154893 | Yes |
79 | 19632 | 6544.0 | 578.04 | 192.7 | Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. | Da Wei Huang, Brad T Sherman, Richard A Lempicki | Nat Protoc | 2009 | 19131956 | Yes |
80 | 13069 | 6534.5 | 300.6 | 150.3 | Processing of X-ray diffraction data collected in oscillation mode. | Z Otwinowski, W Minor | Methods Enzymol | 1997 | 27754618 | Yes |
81 | 12981 | 6490.5 | 355.34 | 177.7 | MrBayes 3: Bayesian phylogenetic inference under mixed models. | Fredrik Ronquist, John P Huelsenbeck | Bioinformatics | 2003 | 12912839 | Yes |
82 | 6489 | 6489.0 | 0.0 | 0.0 | COPPER ENZYMES IN ISOLATED CHLOROPLASTS. POLYPHENOLOXIDASE IN BETA VULGARIS. | D I Arnon | Plant Physiol | 1949 | 16654194 | Yes |
83 | 19434 | 6478.0 | 557.29 | 185.8 | VMD: visual molecular dynamics. | W Humphrey, A Dalke, K Schulten | J Mol Graph | 1996 | 8744570 | Yes |
84 | 12904 | 6452.0 | 0.0 | 0.0 | The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. | K Weber, M Osborn | J Biol Chem | 1969 | 5806584 | Yes |
85 | 6448 | 6448.0 | 193.66 | 193.7 | Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. | M C Hochberg | Arthritis Rheum | 1997 | 9324032 | Yes |
86 | 25602 | 6400.5 | 1140.8 | 285.2 | A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. | M E Charlson, P Pompei, K L Ales, C R MacKenzie | J Chronic Dis | 1987 | 3558716 | Yes |
87 | 12798 | 6399.0 | 401.9 | 200.9 | Efficient iterative schemes for ab initio total-energy calculations using a plane-wave basis set. | Kresse, Furthmüller | Phys Rev B Condens Matter | 1996 | 9984901 | Yes |
88 | 6278 | 6278.0 | 206.97 | 207.0 | AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. | R W Cox | Comput Biomed Res | 1996 | 8812068 | Yes |
89 | 6269 | 6269.0 | 188.39 | 188.4 | Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. | F Tajima | Genetics | 1989 | 2513255 | Yes |
90 | 43734 | 6247.7 | 1269.46 | 181.4 | Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. | S F Altschul, T L Madden, A A Schäffer, J Zhang, Z Zhang, W Miller, D J Lipman | Nucleic Acids Res | 1997 | 9254694 | No |
91 | 6213 | 6213.0 | 196.97 | 197.0 | TreeView: an application to display phylogenetic trees on personal computers. | R D Page | Comput Appl Biosci | 1996 | 8902363 | Yes |
92 | 6154 | 6154.0 | 145.4 | 145.4 | Chromatin modifications and their function. | Tony Kouzarides | Cell | 2007 | 17320507 | No |
93 | 6127 | 6127.0 | 200.89 | 200.9 | Semiempirical GGA-type density functional constructed with a long-range dispersion correction. | Stefan Grimme | J Comput Chem | 2006 | 16955487 | Yes |
94 | 6098 | 6098.0 | 164.93 | 164.9 | PAML 4: phylogenetic analysis by maximum likelihood. | Ziheng Yang | Mol Biol Evol | 2007 | 17483113 | Yes |
95 | 12178 | 6089.0 | 367.28 | 183.6 | Analyzing real-time PCR data by the comparative C(T) method. | Thomas D Schmittgen, Kenneth J Livak | Nat Protoc | 2008 | 18546601 | Yes |
96 | 12155 | 6077.5 | 287.22 | 143.6 | Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana. | S J Clough, A F Bent | Plant J | 1998 | 10069079 | Yes |
97 | 24191 | 6047.8 | 915.36 | 228.8 | Bias in meta-analysis detected by a simple, graphical test. | M Egger, G Davey Smith, M Schneider, C Minder | BMJ | 1997 | 9310563 | Yes |
98 | 5899 | 5899.0 | 167.16 | 167.2 | Fast robust automated brain extraction. | Stephen M Smith | Hum Brain Mapp | 2002 | 12391568 | No |
99 | 5837 | 5837.0 | 235.03 | 235.0 | Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. | P S Thomas | Proc Natl Acad Sci U S A | 1980 | 6159641 | Yes |
100 | 17504 | 5834.7 | 740.11 | 246.7 | NIH Image to ImageJ: 25 years of image analysis. | Caroline A Schneider, Wayne S Rasband, Kevin W Eliceiri | Nat Methods | 2012 | 22930834 | No |
101 | 5823 | 5823.0 | 212.16 | 212.2 | The blockade of immune checkpoints in cancer immunotherapy. | Drew M Pardoll | Nat Rev Cancer | 2012 | 22437870 | No |
102 | 5778 | 5778.0 | 221.84 | 221.8 | "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. | W N Burnette | Anal Biochem | 1981 | 6266278 | Yes |
103 | 23008 | 5752.0 | 1090.54 | 272.6 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | PLoS Med | 2009 | 19621072 | No |
104 | 5719 | 5719.0 | 0.0 | 0.0 | A simplification of the protein assay method of Lowry et al. which is more generally applicable. | G L Peterson | Anal Biochem | 1977 | 603028 | Yes |
105 | 5677 | 5677.0 | 244.52 | 244.5 | Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. | Andreas Stang | Eur J Epidemiol | 2010 | 20652370 | Yes |
106 | 5566 | 5566.0 | 226.98 | 227.0 | Ethical guidelines for investigations of experimental pain in conscious animals. | Manfred Zimmermann | Pain | 1983 | 6877845 | No |
107 | 5555 | 5555.0 | 0.0 | 0.0 | Solvent content of protein crystals. | B W Matthews | J Mol Biol | 1968 | 5700707 | Yes |
108 | 5534 | 5534.0 | 186.29 | 186.3 | The VideoToolbox software for visual psychophysics: transforming numbers into movies. | D G Pelli | Spat Vis | 1997 | 9176953 | Yes |
109 | 5405 | 5405.0 | 322.83 | 322.8 | Comparative fit indexes in structural models. | P M Bentler | Psychol Bull | 1990 | 2320703 | Yes |
110 | 10791 | 5395.5 | 402.72 | 201.4 | Sequencing end-labeled DNA with base-specific chemical cleavages. | A M Maxam, W Gilbert | Methods Enzymol | 1980 | 6246368 | Yes |
111 | 5335 | 5335.0 | 160.98 | 161.0 | Apoptosis: a review of programmed cell death. | Susan Elmore | Toxicol Pathol | 2007 | 17562483 | No |
112 | 5307 | 5307.0 | 0.0 | 0.0 | A low-viscosity epoxy resin embedding medium for electron microscopy. | A R Spurr | J Ultrastruct Res | 1969 | 4887011 | Yes |
113 | 5304 | 5304.0 | 173.74 | 173.7 | Canonical dynamics: Equilibrium phase-space distributions. | Hoover | Phys Rev A Gen Phys | 1985 | 9895674 | Yes |
114 | 10581 | 5290.5 | 238.82 | 119.4 | KEGG: kyoto encyclopedia of genes and genomes. | M Kanehisa, S Goto | Nucleic Acids Res | 2000 | 10592173 | Yes |
115 | 5237 | 5237.0 | 0.0 | 0.0 | Evaluation of survival data and two new rank order statistics arising in its consideration. | N Mantel | Cancer Chemother Rep | 1966 | 5910392 | Yes |
116 | 5232 | 5232.0 | 115.35 | 115.3 | Integrins: bidirectional, allosteric signaling machines. | Richard O Hynes | Cell | 2002 | 12297042 | No |
117 | 15625 | 5208.3 | 0.0 | 0.0 | Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. | W T Friedewald, R I Levy, D S Fredrickson | Clin Chem | 1972 | 4337382 | Yes |
118 | 15554 | 5184.7 | 572.07 | 190.7 | A new generation of Ca2+ indicators with greatly improved fluorescence properties. | G Grynkiewicz, M Poenie, R Y Tsien | J Biol Chem | 1985 | 3838314 | Yes |
119 | 5164 | 5164.0 | 0.0 | 0.0 | Tumor angiogenesis: therapeutic implications. | J Folkman | N Engl J Med | 1971 | 4938153 | No |
120 | 15446 | 5148.7 | 741.2 | 247.1 | Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. | Michael I Love, Wolfgang Huber, Simon Anders | Genome Biol | 2014 | 25516281 | Yes |
121 | 5143 | 5143.0 | 201.3 | 201.3 | The role of protein kinase C in cell surface signal transduction and tumour promotion. | Y Nishizuka | Nature | 1984 | 6232463 | No |
122 | 5081 | 5081.0 | 127.97 | 128.0 | Inflammation in atherosclerosis. | Peter Libby | Nature | 2002 | 12490960 | No |
123 | 5067 | 5067.0 | 137.97 | 138.0 | Inflammation, atherosclerosis, and coronary artery disease. | Göran K Hansson | N Engl J Med | 2005 | 15843671 | No |
124 | 10080 | 5040.0 | 506.34 | 253.2 | MAFFT multiple sequence alignment software version 7: improvements in performance and usability. | Kazutaka Katoh, Daron M Standley | Mol Biol Evol | 2013 | 23329690 | Yes |
125 | 5032 | 5032.0 | 153.03 | 153.0 | Angiogenesis in cancer, vascular, rheumatoid and other disease. | J Folkman | Nat Med | 1995 | 7584949 | No |
126 | 5018 | 5018.0 | 192.63 | 192.6 | The Clinical Dementia Rating (CDR): current version and scoring rules. | J C Morris | Neurology | 1993 | 8232972 | Yes |
127 | 5017 | 5017.0 | 214.36 | 214.4 | Density-functional approximation for the correlation energy of the inhomogeneous electron gas. | Perdew | Phys Rev B Condens Matter | 1986 | 9938299 | Yes |
128 | 9925 | 4962.5 | 0.0 | 0.0 | A rapid alkaline extraction procedure for screening recombinant plasmid DNA. | H C Birnboim, J Doly | Nucleic Acids Res | 1979 | 388356 | Yes |
129 | 4961 | 4961.0 | 99.15 | 99.2 | BLAT--the BLAST-like alignment tool. | W James Kent | Genome Res | 2002 | 11932250 | Yes |
130 | 4936 | 4936.0 | 119.09 | 119.1 | p53, the cellular gatekeeper for growth and division. | A J Levine | Cell | 1997 | 9039259 | No |
131 | 4936 | 4936.0 | 135.18 | 135.2 | Biochemistry and molecular cell biology of diabetic complications. | M Brownlee | Nature | 2001 | 11742414 | Yes |
132 | 4931 | 4931.0 | 0.0 | 0.0 | Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. | J R Vane | Nat New Biol | 1971 | 5284360 | Yes |
133 | 14725 | 4908.3 | 1359.01 | 453.0 | MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets. | Sudhir Kumar, Glen Stecher, Koichiro Tamura | Mol Biol Evol | 2016 | 27004904 | Yes |
134 | 9769 | 4884.5 | 266.87 | 133.4 | MRBAYES: Bayesian inference of phylogenetic trees. | J P Huelsenbeck, F Ronquist | Bioinformatics | 2001 | 11524383 | Yes |
135 | 4876 | 4876.0 | 0.0 | 0.0 | The assessment of anxiety states by rating. | M HAMILTON | Br J Med Psychol | 1959 | 13638508 | Yes |
136 | 9705 | 4852.5 | 252.97 | 126.5 | A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. | Stéphane Guindon, Olivier Gascuel | Syst Biol | 2003 | 14530136 | Yes |
137 | 4850 | 4850.0 | 0.0 | 0.0 | Development of a rating scale for primary depressive illness. | M Hamilton | Br J Soc Clin Psychol | 1967 | 6080235 | Yes |
138 | 9616 | 4808.0 | 0.0 | 0.0 | Continuous cultures of fused cells secreting antibody of predefined specificity. | G Köhler, C Milstein | Nature | 1975 | 1172191 | Yes |
139 | 14408 | 4802.7 | 760.23 | 253.4 | Trimmomatic: a flexible trimmer for Illumina sequence data. | Anthony M Bolger, Marc Lohse, Bjoern Usadel | Bioinformatics | 2014 | 24695404 | Yes |
140 | 4798 | 4798.0 | 131.41 | 131.4 | Free radicals in the physiological control of cell function. | Wulf Dröge | Physiol Rev | 2002 | 11773609 | No |
141 | 9560 | 4780.0 | 236.88 | 118.4 | Dendritic cells and the control of immunity. | J Banchereau, R M Steinman | Nature | 1998 | 9521319 | No |
142 | 9536 | 4768.0 | 306.53 | 153.3 | MODELTEST: testing the model of DNA substitution. | D Posada, K A Crandall | Bioinformatics | 1998 | 9918953 | Yes |
143 | 9534 | 4767.0 | 0.0 | 0.0 | Intraclass correlations: uses in assessing rater reliability. | P E Shrout, J L Fleiss | Psychol Bull | 1979 | 18839484 | No |
144 | 4755 | 4755.0 | 252.85 | 252.8 | Investigation of the freely available easy-to-use software 'EZR' for medical statistics. | Y Kanda | Bone Marrow Transplant | 2013 | 23208313 | Yes |
145 | 9484 | 4742.0 | 0.0 | 0.0 | Prediction of creatinine clearance from serum creatinine. | D W Cockcroft, M H Gault | Nephron | 1976 | 1244564 | Yes |
146 | 4742 | 4742.0 | 0.0 | 0.0 | Modification of seizure activity by electrical stimulation. II. Motor seizure. | R J Racine | Electroencephalogr Clin Neurophysiol | 1972 | 4110397 | Yes |
147 | 9477 | 4738.5 | 0.0 | 0.0 | Statistical aspects of the analysis of data from retrospective studies of disease. | N MANTEL, W HAENSZEL | J Natl Cancer Inst | 1959 | 13655060 | Yes |
148 | 9446 | 4723.0 | 409.39 | 204.7 | The meaning and use of the area under a receiver operating characteristic (ROC) curve. | J A Hanley, B J McNeil | Radiology | 1982 | 7063747 | Yes |
149 | 9396 | 4698.0 | 230.72 | 115.4 | One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. | K A Datsenko, B L Wanner | Proc Natl Acad Sci U S A | 2000 | 10829079 | Yes |
150 | 23431 | 4686.2 | 724.47 | 144.9 | The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. | J D Thompson, T J Gibson, F Plewniak, F Jeanmougin, D G Higgins | Nucleic Acids Res | 1997 | 9396791 | Yes |
151 | 4666 | 4666.0 | 136.25 | 136.2 | Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. | T A Springer | Cell | 1994 | 7507411 | No |
152 | 4653 | 4653.0 | 173.43 | 173.4 | jModelTest: phylogenetic model averaging. | David Posada | Mol Biol Evol | 2008 | 18397919 | Yes |
153 | 4641 | 4641.0 | 162.47 | 162.5 | The steroid and thyroid hormone receptor superfamily. | R M Evans | Science | 1988 | 3283939 | No |
154 | 4613 | 4613.0 | 145.01 | 145.0 | Inositol trisphosphate and calcium signalling. | M J Berridge | Nature | 1993 | 8381210 | No |
155 | 4601 | 4601.0 | 193.54 | 193.5 | The Strengths and Difficulties Questionnaire: a research note. | R Goodman | J Child Psychol Psychiatry | 1997 | 9255702 | Yes |
156 | 9160 | 4580.0 | 0.0 | 0.0 | Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. | Y Cheng, W H Prusoff | Biochem Pharmacol | 1973 | 4202581 | Yes |
157 | 13689 | 4563.0 | 508.48 | 169.5 | Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. | Daniel Dindo, Nicolas Demartines, Pierre-Alain Clavien | Ann Surg | 2004 | 15273542 | Yes |
158 | 4554 | 4554.0 | 113.71 | 113.7 | Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis. | J Castresana | Mol Biol Evol | 2000 | 10742046 | Yes |
159 | 4547 | 4547.0 | 124.14 | 124.1 | Inflammation and metabolic disorders. | Gökhan S Hotamisligil | Nature | 2006 | 17167474 | No |
160 | 4508 | 4508.0 | 120.29 | 120.3 | Antimicrobial peptides of multicellular organisms. | Michael Zasloff | Nature | 2002 | 11807545 | Yes |
161 | 13470 | 4490.0 | 0.0 | 0.0 | Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. | H Ohkawa, N Ohishi, K Yagi | Anal Biochem | 1979 | 36810 | Yes |
162 | 4488 | 4488.0 | 112.22 | 112.2 | The biochemistry of apoptosis. | M O Hengartner | Nature | 2000 | 11048727 | No |
163 | 4428 | 4428.0 | 94.22 | 94.2 | Epithelial-mesenchymal transitions in tumour progression. | Jean Paul Thiery | Nat Rev Cancer | 2002 | 12189386 | No |
164 | 4405 | 4405.0 | 123.51 | 123.5 | The NF-kappa B and I kappa B proteins: new discoveries and insights. | A S Baldwin | Annu Rev Immunol | 1996 | 8717528 | No |
165 | 4383 | 4383.0 | 118.75 | 118.8 | Rapid and efficient site-specific mutagenesis without phenotypic selection. | T A Kunkel | Proc Natl Acad Sci U S A | 1985 | 3881765 | Yes |
166 | 17460 | 4365.0 | 598.71 | 149.7 | MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. | Koichiro Tamura, Joel Dudley, Masatoshi Nei, Sudhir Kumar | Mol Biol Evol | 2007 | 17488738 | Yes |
167 | 4346 | 4346.0 | 148.27 | 148.3 | Adhesion receptors of the immune system. | T A Springer | Nature | 1990 | 1974032 | No |
168 | 4322 | 4322.0 | 95.48 | 95.5 | Rho GTPases and the actin cytoskeleton. | A Hall | Science | 1998 | 9438836 | No |
169 | 4320 | 4320.0 | 0.0 | 0.0 | Selective extraction of polyoma DNA from infected mouse cell cultures. | B Hirt | J Mol Biol | 1967 | 4291934 | Yes |
170 | 8625 | 4312.5 | 250.18 | 125.1 | Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features. | W Kabsch, C Sander | Biopolymers | 1983 | 6667333 | Yes |
171 | 4312 | 4312.0 | 241.18 | 241.2 | UPARSE: highly accurate OTU sequences from microbial amplicon reads. | Robert C Edgar | Nat Methods | 2013 | 23955772 | Yes |
172 | 4308 | 4308.0 | 130.04 | 130.0 | Apoptosis in the pathogenesis and treatment of disease. | C B Thompson | Science | 1995 | 7878464 | No |
173 | 8595 | 4297.5 | 214.43 | 107.2 | Primer3 on the WWW for general users and for biologist programmers. | S Rozen, H Skaletsky | Methods Mol Biol | 2000 | 10547847 | Yes |
174 | 4286 | 4286.0 | 0.0 | 0.0 | Aging: a theory based on free radical and radiation chemistry. | D HARMAN | J Gerontol | 1956 | 13332224 | Yes |
175 | 12851 | 4283.7 | 392.41 | 130.8 | edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. | Mark D Robinson, Davis J McCarthy, Gordon K Smyth | Bioinformatics | 2010 | 19910308 | Yes |
176 | 4268 | 4268.0 | 0.0 | 0.0 | The thiobarbituric acid assay of sialic acids. | L WARREN | J Biol Chem | 1959 | 13672998 | Yes |
177 | 4261 | 4261.0 | 153.76 | 153.8 | Developments of a water-maze procedure for studying spatial learning in the rat. | R Morris | J Neurosci Methods | 1984 | 6471907 | Yes |
178 | 4256 | 4256.0 | 118.77 | 118.8 | Emotion circuits in the brain. | J E LeDoux | Annu Rev Neurosci | 2000 | 10845062 | No |
179 | 4245 | 4245.0 | 0.0 | 0.0 | THE ENVIRONMENT AND DISEASE: ASSOCIATION OR CAUSATION? | A B HILL | Proc R Soc Med | 1965 | 14283879 | Yes |
180 | 12695 | 4231.7 | 476.81 | 158.9 | A simple salting out procedure for extracting DNA from human nucleated cells. | S A Miller, D D Dykes, H F Polesky | Nucleic Acids Res | 1988 | 3344216 | Yes |
181 | 8440 | 4220.0 | 351.63 | 175.8 | Three approaches to qualitative content analysis. | Hsiu-Fang Hsieh, Sarah E Shannon | Qual Health Res | 2005 | 16204405 | Yes |
182 | 4212 | 4212.0 | 0.0 | 0.0 | Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. | F Tietze | Anal Biochem | 1969 | 4388022 | Yes |
183 | 4209 | 4209.0 | 132.6 | 132.6 | A modified poisson regression approach to prospective studies with binary data. | Guangyong Zou | Am J Epidemiol | 2004 | 15033648 | Yes |
184 | 16790 | 4197.5 | 0.0 | 0.0 | Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. | J M Chirgwin, A E Przybyla, R J MacDonald, W J Rutter | Biochemistry | 1979 | 518835 | Yes |
185 | 8329 | 4164.5 | 225.3 | 112.7 | Comparative protein modelling by satisfaction of spatial restraints. | A Sali, T L Blundell | J Mol Biol | 1993 | 8254673 | Yes |
186 | 12403 | 4134.3 | 338.06 | 112.7 | Inference of population structure using multilocus genotype data. | J K Pritchard, M Stephens, P Donnelly | Genetics | 2000 | 10835412 | Yes |
187 | 20533 | 4106.6 | 1185.96 | 237.2 | MEGA6: Molecular Evolutionary Genetics Analysis version 6.0. | Koichiro Tamura, Glen Stecher, Daniel Peterson, Alan Filipski, Sudhir Kumar | Mol Biol Evol | 2013 | 24132122 | Yes |
188 | 4103 | 4103.0 | 0.0 | 0.0 | A SELF-RATING DEPRESSION SCALE. | W W ZUNG | Arch Gen Psychiatry | 1965 | 14221692 | Yes |
189 | 12305 | 4101.7 | 444.26 | 148.1 | The PHQ-9: validity of a brief depression severity measure. | K Kroenke, R L Spitzer, J B Williams | J Gen Intern Med | 2001 | 11556941 | Yes |
190 | 4091 | 4091.0 | 191.77 | 191.8 | Orienting of attention. | M I Posner | Q J Exp Psychol | 1980 | 7367577 | Yes |
191 | 4079 | 4079.0 | 131.27 | 131.3 | G proteins: transducers of receptor-generated signals. | A G Gilman | Annu Rev Biochem | 1987 | 3113327 | No |
192 | 4071 | 4071.0 | 131.21 | 131.2 | A fast diffeomorphic image registration algorithm. | John Ashburner | Neuroimage | 2007 | 17761438 | Yes |
193 | 8107 | 4053.5 | 282.35 | 141.2 | Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. | H Schägger, G von Jagow | Anal Biochem | 1987 | 2449095 | Yes |
194 | 8101 | 4050.5 | 256.58 | 128.3 | EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis. | Arnaud Delorme, Scott Makeig | J Neurosci Methods | 2004 | 15102499 | Yes |
195 | 8073 | 4036.5 | 254.16 | 127.1 | Neuropathological stageing of Alzheimer-related changes. | H Braak, E Braak | Acta Neuropathol | 1991 | 1759558 | No |
196 | 8026 | 4013.0 | 191.06 | 95.5 | Inflammation and cancer. | Lisa M Coussens, Zena Werb | Nature | 2002 | 12490959 | No |
197 | 4009 | 4009.0 | 97.7 | 97.7 | MUSCLE: a multiple sequence alignment method with reduced time and space complexity. | Robert C Edgar | BMC Bioinformatics | 2004 | 15318951 | Yes |
198 | 4007 | 4007.0 | 249.1 | 249.1 | Prokka: rapid prokaryotic genome annotation. | Torsten Seemann | Bioinformatics | 2014 | 24642063 | Yes |
199 | 12017 | 4005.7 | 436.62 | 145.5 | Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. | C Yanisch-Perron, J Vieira, J Messing | Gene | 1985 | 2985470 | Yes |
200 | 3956 | 3956.0 | 89.19 | 89.2 | Targeting HIF-1 for cancer therapy. | Gregg L Semenza | Nat Rev Cancer | 2003 | 13130303 | No |
201 | 7897 | 3948.5 | 0.0 | 0.0 | A series of normal stages in the development of the chick embryo. | V HAMBURGER, H L HAMILTON | J Morphol | 1951 | 24539719 | Yes |
202 | 3942 | 3942.0 | 79.0 | 79.0 | DNA methylation patterns and epigenetic memory. | Adrian Bird | Genes Dev | 2002 | 11782440 | No |
203 | 3938 | 3938.0 | 140.46 | 140.5 | New M13 vectors for cloning. | J Messing | Methods Enzymol | 1983 | 6310323 | Yes |
204 | 23614 | 3935.7 | 1088.75 | 181.5 | MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. | Koichiro Tamura, Daniel Peterson, Nicholas Peterson, Glen Stecher, Masatoshi Nei, Sudhir Kumar | Mol Biol Evol | 2011 | 21546353 | Yes |
205 | 7860 | 3930.0 | 305.88 | 152.9 | Operating characteristics of a rank correlation test for publication bias. | C B Begg, M Mazumdar | Biometrics | 1994 | 7786990 | Yes |
206 | 7829 | 3914.5 | 210.56 | 105.3 | BEDTools: a flexible suite of utilities for comparing genomic features. | Aaron R Quinlan, Ira M Hall | Bioinformatics | 2010 | 20110278 | Yes |
207 | 23468 | 3911.3 | 1027.6 | 171.3 | Global cancer statistics. | Ahmedin Jemal, Freddie Bray, Melissa M Center, Jacques Ferlay, Elizabeth Ward, David Forman | CA Cancer J Clin | 2011 | 21296855 | Yes |
208 | 7799 | 3899.5 | 190.97 | 95.5 | The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. | John Hardy, Dennis J Selkoe | Science | 2002 | 12130773 | No |
209 | 3895 | 3895.0 | 74.03 | 74.0 | Generalized lacZ expression with the ROSA26 Cre reporter strain. | P Soriano | Nat Genet | 1999 | 9916792 | Yes |
210 | 7776 | 3888.0 | 0.0 | 0.0 | A quantitative description of membrane current and its application to conduction and excitation in nerve. | A L HODGKIN, A F HUXLEY | J Physiol | 1952 | 12991237 | Yes |
211 | 11644 | 3881.3 | 277.92 | 92.6 | Refinement of macromolecular structures by the maximum-likelihood method. | G N Murshudov, A A Vagin, E J Dodson | Acta Crystallogr D Biol Crystallogr | 1997 | 15299926 | Yes |
212 | 7752 | 3876.0 | 228.64 | 114.3 | Differential expression analysis for sequence count data. | Simon Anders, Wolfgang Huber | Genome Biol | 2010 | 20979621 | Yes |
213 | 11569 | 3856.3 | 517.61 | 172.5 | The positive and negative syndrome scale (PANSS) for schizophrenia. | S R Kay, A Fiszbein, L A Opler | Schizophr Bull | 1987 | 3616518 | Yes |
214 | 3795 | 3795.0 | 101.23 | 101.2 | An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs. | M Kozak | Nucleic Acids Res | 1987 | 3313277 | No |
215 | 3733 | 3733.0 | 85.52 | 85.5 | Alternative activation of macrophages. | Siamon Gordon | Nat Rev Immunol | 2003 | 12511873 | No |
216 | 3732 | 3732.0 | 92.05 | 92.0 | Prions. | S B Prusiner | Proc Natl Acad Sci U S A | 1998 | 9811807 | No |
217 | 3731 | 3731.0 | 0.0 | 0.0 | Mutation and cancer: statistical study of retinoblastoma. | A G Knudson | Proc Natl Acad Sci U S A | 1971 | 5279523 | Yes |
218 | 3722 | 3722.0 | 0.0 | 0.0 | Tetramethyl benzidine for horseradish peroxidase neurohistochemistry: a non-carcinogenic blue reaction product with superior sensitivity for visualizing neural afferents and efferents. | M M Mesulam | J Histochem Cytochem | 1978 | 24068 | Yes |
219 | 7444 | 3722.0 | 0.0 | 0.0 | Assessment of older people: self-maintaining and instrumental activities of daily living. | M P Lawton, E M Brody | Gerontologist | 1969 | 5349366 | Yes |
220 | 3720 | 3720.0 | 0.0 | 0.0 | Preparation of isolated rat liver cells. | P O Seglen | Methods Cell Biol | 1976 | 177845 | No |
221 | 3717 | 3717.0 | 119.87 | 119.9 | The Cambridge Structural Database: a quarter of a million crystal structures and rising. | Frank H Allen | Acta Crystallogr B | 2002 | 12037359 | Yes |
222 | 3716 | 3716.0 | 0.0 | 0.0 | Index for rating diagnostic tests. | W J YOUDEN | Cancer | 1950 | 15405679 | Yes |
223 | 7422 | 3711.0 | 0.0 | 0.0 | FUNCTIONAL EVALUATION: THE BARTHEL INDEX. | F I MAHONEY, D W BARTHEL | Md State Med J | 1965 | 14258950 | Yes |
224 | 7420 | 3710.0 | 280.0 | 140.0 | AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. | Oleg Trott, Arthur J Olson | J Comput Chem | 2010 | 19499576 | Yes |
225 | 7415 | 3707.5 | 0.0 | 0.0 | A new depression scale designed to be sensitive to change. | S A Montgomery, M Asberg | Br J Psychiatry | 1979 | 444788 | Yes |
226 | 3689 | 3689.0 | 114.59 | 114.6 | Mild cognitive impairment as a diagnostic entity. | R C Petersen | J Intern Med | 2004 | 15324362 | No |
227 | 3687 | 3687.0 | 91.87 | 91.9 | Alzheimer's disease: genes, proteins, and therapy. | D J Selkoe | Physiol Rev | 2001 | 11274343 | No |
228 | 7374 | 3687.0 | 0.0 | 0.0 | THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE. | T OMURA, R SATO | J Biol Chem | 1964 | 14209971 | Yes |
229 | 7359 | 3679.5 | 231.89 | 115.9 | A synaptic model of memory: long-term potentiation in the hippocampus. | T V Bliss, G L Collingridge | Nature | 1993 | 8421494 | No |
230 | 3643 | 3643.0 | 182.59 | 182.6 | Revisiting the behavioral model and access to medical care: does it matter? | R M Andersen | J Health Soc Behav | 1995 | 7738325 | Yes |
231 | 7282 | 3641.0 | 343.03 | 171.5 | The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. | R F Furchgott, J V Zawadzki | Nature | 1980 | 6253831 | Yes |
232 | 7280 | 3640.0 | 190.01 | 95.0 | SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. | N Guex, M C Peitsch | Electrophoresis | 1997 | 9504803 | Yes |
233 | 3638 | 3638.0 | 0.0 | 0.0 | The McGill Pain Questionnaire: major properties and scoring methods. | Ronald Melzack | Pain | 1975 | 1235985 | Yes |
234 | 3621 | 3621.0 | 89.04 | 89.0 | Cancer cell cycles. | C J Sherr | Science | 1996 | 8939849 | No |
235 | 7225 | 3612.5 | 230.02 | 115.0 | The rise of graphene. | A K Geim, K S Novoselov | Nat Mater | 2007 | 17330084 | Yes |
236 | 10831 | 3610.3 | 377.21 | 125.7 | A comprehensive set of sequence analysis programs for the VAX. | J Devereux, P Haeberli, O Smithies | Nucleic Acids Res | 1984 | 6546423 | Yes |
237 | 3610 | 3610.0 | 81.39 | 81.4 | Wnt/beta-catenin signaling in development and disease. | Hans Clevers | Cell | 2006 | 17081971 | No |
238 | 3602 | 3602.0 | 0.0 | 0.0 | The genetical evolution of social behaviour. I. | W D Hamilton | J Theor Biol | 1964 | 5875341 | Yes |
239 | 3598 | 3598.0 | 178.81 | 178.8 | Oxygen-derived free radicals in postischemic tissue injury. | J M McCord | N Engl J Med | 1985 | 2981404 | No |
240 | 10760 | 3586.7 | 885.77 | 295.3 | Cancer statistics, 2016. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2016 | 26742998 | Yes |
241 | 3575 | 3575.0 | 75.04 | 75.0 | The phosphoinositide 3-kinase pathway. | Lewis C Cantley | Science | 2002 | 12040186 | No |
242 | 17845 | 3569.0 | 0.0 | 0.0 | An inventory for measuring depression. | A T BECK, C H WARD, M MENDELSON, J MOCK, J ERBAUGH | Arch Gen Psychiatry | 1961 | 13688369 | Yes |
243 | 3563 | 3563.0 | 0.0 | 0.0 | THE TWO HISTOLOGICAL MAIN TYPES OF GASTRIC CARCINOMA: DIFFUSE AND SO-CALLED INTESTINAL-TYPE CARCINOMA. AN ATTEMPT AT A HISTO-CLINICAL CLASSIFICATION. | P LAUREN | Acta Pathol Microbiol Scand | 1965 | 14320675 | Yes |
244 | 7091 | 3545.5 | 0.0 | 0.0 | A new technique for the assay of infectivity of human adenovirus 5 DNA. | F L Graham, A J van der Eb | Virology | 1973 | 4705382 | Yes |
245 | 3532 | 3532.0 | 114.17 | 114.2 | How mitochondria produce reactive oxygen species. | Michael P Murphy | Biochem J | 2009 | 19061483 | No |
246 | 7018 | 3509.0 | 229.25 | 114.6 | Improved tools for biological sequence comparison. | W R Pearson, D J Lipman | Proc Natl Acad Sci U S A | 1988 | 3162770 | Yes |
247 | 3509 | 3509.0 | 0.0 | 0.0 | The detection of disease clustering and a generalized regression approach. | N Mantel | Cancer Res | 1967 | 6018555 | Yes |
248 | 3507 | 3507.0 | 93.86 | 93.9 | Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. | M Kozak | Cell | 1986 | 3943125 | Yes |
249 | 7011 | 3505.5 | 179.47 | 89.7 | Collective dynamics of 'small-world' networks. | D J Watts, S H Strogatz | Nature | 1998 | 9623998 | Yes |
250 | 3488 | 3488.0 | 83.29 | 83.3 | PAML: a program package for phylogenetic analysis by maximum likelihood. | Z Yang | Comput Appl Biosci | 1997 | 9367129 | Yes |
251 | 3463 | 3463.0 | 81.97 | 82.0 | Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. | C J Marshall | Cell | 1995 | 7834738 | No |
252 | 3460 | 3460.0 | 140.94 | 140.9 | Studies and perspectives of protein kinase C. | Y Nishizuka | Science | 1986 | 3014651 | No |
253 | 10370 | 3456.7 | 539.83 | 179.9 | Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. | S M Hsu, L Raine, H Fanger | J Histochem Cytochem | 1981 | 6166661 | Yes |
254 | 3446 | 3446.0 | 0.0 | 0.0 | The clonal evolution of tumor cell populations. | P C Nowell | Science | 1976 | 959840 | Yes |
255 | 3438 | 3438.0 | 152.63 | 152.6 | An Introduction to Propensity Score Methods for Reducing the Effects of Confounding in Observational Studies. | Peter C Austin | Multivariate Behav Res | 2011 | 21818162 | Yes |
256 | 6839 | 3419.5 | 193.57 | 96.8 | A genetic model for colorectal tumorigenesis. | E R Fearon, B Vogelstein | Cell | 1990 | 2188735 | No |
257 | 3404 | 3404.0 | 114.4 | 114.4 | A new method for predicting signal sequence cleavage sites. | G von Heijne | Nucleic Acids Res | 1986 | 3714490 | Yes |
258 | 3402 | 3402.0 | 89.94 | 89.9 | Mechanisms of angiogenesis. | W Risau | Nature | 1997 | 9109485 | No |
259 | 6801 | 3400.5 | 152.47 | 76.2 | A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. | R S Sikorski, P Hieter | Genetics | 1989 | 2659436 | Yes |
260 | 10200 | 3400.0 | 463.38 | 154.5 | Nitric oxide: physiology, pathophysiology, and pharmacology. | S Moncada, R M Palmer, E A Higgs | Pharmacol Rev | 1991 | 1852778 | No |
261 | 6771 | 3385.5 | 0.0 | 0.0 | Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). | J M McCord, I Fridovich | J Biol Chem | 1969 | 5389100 | Yes |
262 | 3369 | 3369.0 | 0.0 | 0.0 | Traumatic arthritis of the hip after dislocation and acetabular fractures: treatment by mold arthroplasty. An end-result study using a new method of result evaluation. | W H Harris | J Bone Joint Surg Am | 1969 | 5783851 | Yes |
263 | 3368 | 3368.0 | 123.72 | 123.7 | Updating P300: an integrative theory of P3a and P3b. | John Polich | Clin Neurophysiol | 2007 | 17573239 | No |
264 | 13453 | 3363.2 | 522.42 | 130.6 | G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. | Franz Faul, Edgar Erdfelder, Albert-Georg Lang, Axel Buchner | Behav Res Methods | 2007 | 17695343 | Yes |
265 | 3361 | 3361.0 | 262.95 | 262.9 | SHELXT - integrated space-group and crystal-structure determination. | George M Sheldrick | Acta Crystallogr A Found Adv | 2015 | 25537383 | Yes |
266 | 3360 | 3360.0 | 0.0 | 0.0 | Estimation of nuclear population from microtome sections. | M ABERCROMBIE | Anat Rec | 1946 | 21015608 | Yes |
267 | 20130 | 3355.0 | 3148.64 | 524.8 | Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. | Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal | CA Cancer J Clin | 2018 | 30207593 | Yes |
268 | 6707 | 3353.5 | 250.88 | 125.4 | DnaSP v5: a software for comprehensive analysis of DNA polymorphism data. | P Librado, J Rozas | Bioinformatics | 2009 | 19346325 | Yes |
269 | 3336 | 3336.0 | 0.0 | 0.0 | THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS. | L HAYFLICK | Exp Cell Res | 1965 | 14315085 | Yes |
270 | 3325 | 3325.0 | 90.34 | 90.3 | ras oncogenes in human cancer: a review. | J L Bos | Cancer Res | 1989 | 2547513 | No |
271 | 3325 | 3325.0 | 80.13 | 80.1 | Tandem repeats finder: a program to analyze DNA sequences. | G Benson | Nucleic Acids Res | 1999 | 9862982 | Yes |
272 | 3320 | 3320.0 | 149.41 | 149.4 | EuroQol: the current state of play. | R Brooks | Health Policy | 1996 | 10158943 | No |
273 | 3310 | 3310.0 | 99.41 | 99.4 | Sequencing technologies - the next generation. | Michael L Metzker | Nat Rev Genet | 2010 | 19997069 | No |
274 | 6612 | 3306.0 | 132.67 | 66.3 | Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. | A H Brand, N Perrimon | Development | 1993 | 8223268 | Yes |
275 | 3301 | 3301.0 | 97.63 | 97.6 | Staphylococcus aureus infections. | F D Lowy | N Engl J Med | 1998 | 9709046 | No |
276 | 9898 | 3299.3 | 987.07 | 329.0 | Cancer Statistics, 2017. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2017 | 28055103 | Yes |
277 | 3295 | 3295.0 | 84.38 | 84.4 | Apoptosis by death factor. | S Nagata | Cell | 1997 | 9039262 | No |
278 | 6582 | 3291.0 | 160.49 | 80.2 | MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. | Jürgen Cox, Matthias Mann | Nat Biotechnol | 2008 | 19029910 | Yes |
279 | 13163 | 3290.8 | 0.0 | 0.0 | A new and rapid colorimetric determination of acetylcholinesterase activity. | G L ELLMAN, K D COURTNEY, V ANDRES, R M FEATHER-STONE | Biochem Pharmacol | 1961 | 13726518 | Yes |
280 | 6571 | 3285.5 | 0.0 | 0.0 | A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels. | W M Bonner, R A Laskey | Eur J Biochem | 1974 | 4850204 | Yes |
281 | 19675 | 3279.2 | 788.97 | 131.5 | Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. | D R Matthews, J P Hosker, A S Rudenski, B A Naylor, D F Treacher, R C Turner | Diabetologia | 1985 | 3899825 | Yes |
282 | 6554 | 3277.0 | 0.0 | 0.0 | Parkinsonism: onset, progression and mortality. | M M Hoehn, M D Yahr | Neurology | 1967 | 6067254 | Yes |
283 | 3275 | 3275.0 | 127.9 | 127.9 | Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes. | P Matsudaira | J Biol Chem | 1987 | 3611052 | Yes |
284 | 3273 | 3273.0 | 140.6 | 140.6 | Whatever happened to qualitative description? | M Sandelowski | Res Nurs Health | 2000 | 10940958 | No |
285 | 3272 | 3272.0 | 80.33 | 80.3 | Atherosclerosis. | A J Lusis | Nature | 2000 | 11001066 | No |
286 | 12962 | 3240.5 | 395.95 | 99.0 | Global cancer statistics, 2002. | D Max Parkin, Freddie Bray, J Ferlay, Paola Pisani | CA Cancer J Clin | 2005 | 15761078 | Yes |
287 | 3234 | 3234.0 | 123.71 | 123.7 | Glutamate neurotoxicity and diseases of the nervous system. | D W Choi | Neuron | 1988 | 2908446 | No |
288 | 6460 | 3230.0 | 176.62 | 88.3 | tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence. | T M Lowe, S R Eddy | Nucleic Acids Res | 1997 | 9023104 | Yes |
289 | 3222 | 3222.0 | 101.61 | 101.6 | Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing. | S Henikoff | Gene | 1984 | 6235151 | Yes |
290 | 3221 | 3221.0 | 72.55 | 72.5 | Protein secondary structure prediction based on position-specific scoring matrices. | D T Jones | J Mol Biol | 1999 | 10493868 | Yes |
291 | 3211 | 3211.0 | 0.0 | 0.0 | Evolution in Mendelian Populations. | S Wright | Genetics | 1931 | 17246615 | Yes |
292 | 3211 | 3211.0 | 134.3 | 134.3 | ANALYZING TABLES OF STATISTICAL TESTS. | William R Rice | Evolution | 1989 | 28568501 | Yes |
293 | 6415 | 3207.5 | 208.1 | 104.0 | BEAST: Bayesian evolutionary analysis by sampling trees. | Alexei J Drummond, Andrew Rambaut | BMC Evol Biol | 2007 | 17996036 | Yes |
294 | 6414 | 3207.0 | 0.0 | 0.0 | Assessment of coma and impaired consciousness. A practical scale. | G Teasdale, B Jennett | Lancet | 1974 | 4136544 | Yes |
295 | 3207 | 3207.0 | 74.06 | 74.1 | The retinoblastoma protein and cell cycle control. | R A Weinberg | Cell | 1995 | 7736585 | No |
296 | 6411 | 3205.5 | 339.64 | 169.8 | Ligand: a versatile computerized approach for characterization of ligand-binding systems. | P J Munson, D Rodbard | Anal Biochem | 1980 | 6254391 | Yes |
297 | 3205 | 3205.0 | 94.36 | 94.4 | Multiple sequence alignment with hierarchical clustering. | F Corpet | Nucleic Acids Res | 1988 | 2849754 | Yes |
298 | 3200 | 3200.0 | 150.9 | 150.9 | The pathogenesis of atherosclerosis--an update. | R Ross | N Engl J Med | 1986 | 3511384 | No |
299 | 3200 | 3200.0 | 77.47 | 77.5 | Protein production by auto-induction in high density shaking cultures. | F William Studier | Protein Expr Purif | 2005 | 15915565 | Yes |
300 | 3195 | 3195.0 | 72.82 | 72.8 | The green fluorescent protein. | R Y Tsien | Annu Rev Biochem | 1998 | 9759496 | No |
301 | 12766 | 3191.5 | 396.82 | 99.2 | Features and development of Coot. | P Emsley, B Lohkamp, W G Scott, K Cowtan | Acta Crystallogr D Biol Crystallogr | 2010 | 20383002 | Yes |
302 | 3189 | 3189.0 | 0.0 | 0.0 | The need for a new medical model: a challenge for biomedicine. | G L Engel | Science | 1977 | 847460 | Yes |
303 | 3185 | 3185.0 | 83.45 | 83.5 | Why most published research findings are false. | John P A Ioannidis | PLoS Med | 2005 | 16060722 | Yes |
304 | 3181 | 3181.0 | 0.0 | 0.0 | Bone: formation by autoinduction. | M R Urist | Science | 1965 | 5319761 | Yes |
305 | 6355 | 3177.5 | 279.96 | 140.0 | Qualitative content analysis in nursing research: concepts, procedures and measures to achieve trustworthiness. | U H Graneheim, B Lundman | Nurse Educ Today | 2004 | 14769454 | No |
306 | 3175 | 3175.0 | 105.59 | 105.6 | Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. | Y Nishizuka | Science | 1992 | 1411571 | No |
307 | 6331 | 3165.5 | 207.98 | 104.0 | RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. | Bo Li, Colin N Dewey | BMC Bioinformatics | 2011 | 21816040 | Yes |
308 | 3158 | 3158.0 | 98.44 | 98.4 | Propensity score methods for bias reduction in the comparison of a treatment to a non-randomized control group. | R B D'Agostino | Stat Med | 1998 | 9802183 | Yes |
309 | 3147 | 3147.0 | 72.3 | 72.3 | TGF-beta signal transduction. | J Massagué | Annu Rev Biochem | 1998 | 9759503 | No |
310 | 3144 | 3144.0 | 102.36 | 102.4 | Revisions in the International System for Staging Lung Cancer. | C F Mountain | Chest | 1997 | 9187198 | Yes |
311 | 3127 | 3127.0 | 90.46 | 90.5 | The dendritic cell system and its role in immunogenicity. | R M Steinman | Annu Rev Immunol | 1991 | 1910679 | No |
312 | 3125 | 3125.0 | 75.78 | 75.8 | Scaling and assessment of data quality. | Philip Evans | Acta Crystallogr D Biol Crystallogr | 2006 | 16369096 | No |
313 | 9371 | 3123.7 | 0.0 | 0.0 | Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. | W H Habig, M J Pabst, W B Jakoby | J Biol Chem | 1974 | 4436300 | Yes |
314 | 3118 | 3118.0 | 82.67 | 82.7 | Nonalcoholic fatty liver disease. | Paul Angulo | N Engl J Med | 2002 | 11961152 | No |
315 | 9346 | 3115.3 | 478.99 | 159.7 | Cancer statistics, 2013. | Rebecca Siegel, Deepa Naishadham, Ahmedin Jemal | CA Cancer J Clin | 2013 | 23335087 | Yes |
316 | 3106 | 3106.0 | 82.15 | 82.2 | Marrow stromal cells as stem cells for nonhematopoietic tissues. | D J Prockop | Science | 1997 | 9082988 | No |
317 | 3104 | 3104.0 | 77.04 | 77.0 | Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. | Rakesh K Jain | Science | 2005 | 15637262 | No |
318 | 6205 | 3102.5 | 275.5 | 137.8 | Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models. | Kristopher J Preacher, Andrew F Hayes | Behav Res Methods | 2008 | 18697684 | Yes |
319 | 9278 | 3092.7 | 432.65 | 144.2 | A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. | J Ware, M Kosinski, S D Keller | Med Care | 1996 | 8628042 | Yes |
320 | 6175 | 3087.5 | 180.37 | 90.2 | Control of goal-directed and stimulus-driven attention in the brain. | Maurizio Corbetta, Gordon L Shulman | Nat Rev Neurosci | 2002 | 11994752 | No |
321 | 3085 | 3085.0 | 113.21 | 113.2 | genepop'007: a complete re-implementation of the genepop software for Windows and Linux. | François Rousset | Mol Ecol Resour | 2008 | 21585727 | Yes |
322 | 3070 | 3070.0 | 0.0 | 0.0 | A rapid banding technique for human chromosomes. | M Seabright | Lancet | 1971 | 4107917 | Yes |
323 | 3063 | 3063.0 | 67.07 | 67.1 | Hypoxia--a key regulatory factor in tumour growth. | Adrian L Harris | Nat Rev Cancer | 2002 | 11902584 | No |
324 | 9175 | 3058.3 | 230.37 | 76.8 | Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. | J D Dignam, R M Lebovitz, R G Roeder | Nucleic Acids Res | 1983 | 6828386 | Yes |
325 | 3052 | 3052.0 | 114.29 | 114.3 | How do you feel--now? The anterior insula and human awareness. | A D Bud Craig | Nat Rev Neurosci | 2009 | 19096369 | No |
326 | 6098 | 3049.0 | 150.41 | 75.2 | Functional rafts in cell membranes. | K Simons, E Ikonen | Nature | 1997 | 9177342 | No |
327 | 3035 | 3035.0 | 83.17 | 83.2 | Cancer. p53, guardian of the genome. | D P Lane | Nature | 1992 | 1614522 | No |
328 | 6070 | 3035.0 | 171.72 | 85.9 | Mitochondria and apoptosis. | D R Green, J C Reed | Science | 1998 | 9721092 | No |
329 | 3027 | 3027.0 | 66.36 | 66.4 | Mammalian neural stem cells. | F H Gage | Science | 2000 | 10688783 | No |
330 | 3026 | 3026.0 | 70.55 | 70.5 | Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. | G R Martin | Proc Natl Acad Sci U S A | 1981 | 6950406 | Yes |
331 | 9058 | 3019.3 | 475.08 | 158.4 | Development and validation of brief measures of positive and negative affect: the PANAS scales. | D Watson, L A Clark, A Tellegen | J Pers Soc Psychol | 1988 | 3397865 | Yes |
332 | 3013 | 3013.0 | 0.0 | 0.0 | Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies. | C B Laurell | Anal Biochem | 1966 | 5959431 | Yes |
333 | 3012 | 3012.0 | 134.69 | 134.7 | Measuring the accuracy of diagnostic systems. | J A Swets | Science | 1988 | 3287615 | No |
334 | 9034 | 3011.3 | 1287.69 | 429.2 | Cancer statistics, 2018. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2018 | 29313949 | Yes |
335 | 3006 | 3006.0 | 0.0 | 0.0 | A membrane-filter technique for the detection of complementary DNA. | D T Denhardt | Biochem Biophys Res Commun | 1966 | 5963888 | Yes |
336 | 3005 | 3005.0 | 83.38 | 83.4 | Caspases: the executioners of apoptosis. | G M Cohen | Biochem J | 1997 | 9337844 | No |
337 | 6006 | 3003.0 | 0.0 | 0.0 | Microsomal lipid peroxidation. | J A Buege, S D Aust | Methods Enzymol | 1978 | 672633 | Yes |
338 | 3002 | 3002.0 | 91.42 | 91.4 | The adolescent brain and age-related behavioral manifestations. | L P Spear | Neurosci Biobehav Rev | 2000 | 10817843 | No |
339 | 2997 | 2997.0 | 0.0 | 0.0 | A short portable mental status questionnaire for the assessment of organic brain deficit in elderly patients. | E Pfeiffer | J Am Geriatr Soc | 1975 | 1159263 | Yes |
340 | 2988 | 2988.0 | 87.55 | 87.5 | Microglia: a sensor for pathological events in the CNS. | G W Kreutzberg | Trends Neurosci | 1996 | 8843599 | No |
341 | 5975 | 2987.5 | 0.0 | 0.0 | Radiological assessment of osteo-arthrosis. | J H KELLGREN, J S LAWRENCE | Ann Rheum Dis | 1957 | 13498604 | Yes |
342 | 2986 | 2986.0 | 0.0 | 0.0 | METABOLISM OF ISOLATED FAT CELLS. I. EFFECTS OF HORMONES ON GLUCOSE METABOLISM AND LIPOLYSIS. | M RODBELL | J Biol Chem | 1964 | 14169133 | Yes |
343 | 8954 | 2984.7 | 603.39 | 201.1 | Cancer statistics, 2015. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2015 | 25559415 | Yes |
344 | 2980 | 2980.0 | 116.43 | 116.4 | Bacterial evolution. | C R Woese | Microbiol Rev | 1987 | 2439888 | No |
345 | 2965 | 2965.0 | 62.11 | 62.1 | Signal transduction by the JNK group of MAP kinases. | R J Davis | Cell | 2000 | 11057897 | No |
346 | 5930 | 2965.0 | 186.88 | 93.4 | Velvet: algorithms for de novo short read assembly using de Bruijn graphs. | Daniel R Zerbino, Ewan Birney | Genome Res | 2008 | 18349386 | Yes |
347 | 2955 | 2955.0 | 0.0 | 0.0 | Determination of protein: a modification of the Lowry method that gives a linear photometric response. | E F Hartree | Anal Biochem | 1972 | 4115981 | Yes |
348 | 2953 | 2953.0 | 0.0 | 0.0 | Principles that govern the folding of protein chains. | C B Anfinsen | Science | 1973 | 4124164 | Yes |
349 | 2949 | 2949.0 | 104.44 | 104.4 | The molecular heterogeneity of protein kinase C and its implications for cellular regulation. | Y Nishizuka | Nature | 1988 | 3045562 | No |
350 | 11774 | 2943.5 | 312.25 | 78.1 | Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. | Ben Langmead, Cole Trapnell, Mihai Pop, Steven L Salzberg | Genome Biol | 2009 | 19261174 | Yes |
351 | 2937 | 2937.0 | 102.21 | 102.2 | Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. | A H Wyllie | Nature | 1980 | 6245367 | Yes |
352 | 2937 | 2937.0 | 101.5 | 101.5 | What's wrong with Bonferroni adjustments. | T V Perneger | BMJ | 1998 | 9553006 | No |
353 | 5863 | 2931.5 | 170.14 | 85.1 | Genomic sequencing. | G M Church, W Gilbert | Proc Natl Acad Sci U S A | 1984 | 6326095 | Yes |
354 | 2926 | 2926.0 | 136.64 | 136.6 | A concordance correlation coefficient to evaluate reproducibility. | L I Lin | Biometrics | 1989 | 2720055 | Yes |
355 | 5851 | 2925.5 | 112.35 | 56.2 | Translating the histone code. | T Jenuwein, C D Allis | Science | 2001 | 11498575 | No |
356 | 2924 | 2924.0 | 64.91 | 64.9 | Profile hidden Markov models. | S R Eddy | Bioinformatics | 1998 | 9918945 | No |
357 | 5846 | 2923.0 | 296.48 | 148.2 | The timed "Up & Go": a test of basic functional mobility for frail elderly persons. | D Podsiadlo, S Richardson | J Am Geriatr Soc | 1991 | 1991946 | Yes |
358 | 2919 | 2919.0 | 81.96 | 82.0 | Novel proteinaceous infectious particles cause scrapie. | S B Prusiner | Science | 1982 | 6801762 | Yes |
359 | 2911 | 2911.0 | 114.02 | 114.0 | Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD. | Russell A Barkley | Psychol Bull | 1997 | 9000892 | No |
360 | 2907 | 2907.0 | 84.06 | 84.1 | Oxidative stress, antioxidants and stress tolerance. | Ron Mittler | Trends Plant Sci | 2002 | 12234732 | No |
361 | 5812 | 2906.0 | 164.69 | 82.3 | An integrative theory of prefrontal cortex function. | E K Miller, J D Cohen | Annu Rev Neurosci | 2001 | 11283309 | No |
362 | 2906 | 2906.0 | 77.29 | 77.3 | Glutamate uptake. | N C Danbolt | Prog Neurobiol | 2001 | 11369436 | No |
363 | 2902 | 2902.0 | 0.0 | 0.0 | Transformed up-down methods in psychoacoustics. | H Levitt | J Acoust Soc Am | 1971 | 5541744 | Yes |
364 | 17384 | 2897.3 | 1203.94 | 200.7 | Global cancer statistics, 2012. | Lindsey A Torre, Freddie Bray, Rebecca L Siegel, Jacques Ferlay, Joannie Lortet-Tieulent, Ahmedin Jemal | CA Cancer J Clin | 2015 | 25651787 | Yes |
365 | 2896 | 2896.0 | 71.63 | 71.6 | Instability and decay of the primary structure of DNA. | T Lindahl | Nature | 1993 | 8469282 | No |
366 | 2896 | 2896.0 | 102.02 | 102.0 | Protective and damaging effects of stress mediators. | B S McEwen | N Engl J Med | 1998 | 9428819 | No |
367 | 2887 | 2887.0 | 0.0 | 0.0 | The Scree Test For The Number Of Factors. | R B Cattell | Multivariate Behav Res | 1966 | 26828106 | Yes |
368 | 2885 | 2885.0 | 97.95 | 98.0 | What is the evidence that tumors are angiogenesis dependent? | J Folkman | J Natl Cancer Inst | 1990 | 1688381 | No |
369 | 2885 | 2885.0 | 81.5 | 81.5 | I-TASSER server for protein 3D structure prediction. | Yang Zhang | BMC Bioinformatics | 2008 | 18215316 | Yes |
370 | 5741 | 2870.5 | 0.0 | 0.0 | Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. | D E Paglia, W N Valentine | J Lab Clin Med | 1967 | 6066618 | Yes |
371 | 2856 | 2856.0 | 0.0 | 0.0 | Amino acid metabolism in mammalian cell cultures. | H EAGLE | Science | 1959 | 13675766 | Yes |
372 | 5709 | 2854.5 | 123.0 | 61.5 | Statistical significance for genomewide studies. | John D Storey, Robert Tibshirani | Proc Natl Acad Sci U S A | 2003 | 12883005 | Yes |
373 | 8554 | 2851.3 | 323.35 | 107.8 | Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. | E R DeLong, D M DeLong, D L Clarke-Pearson | Biometrics | 1988 | 3203132 | Yes |
374 | 2849 | 2849.0 | 0.0 | 0.0 | New methods for calculating metabolic rate with special reference to protein metabolism. | J B DE B WEIR | J Physiol | 1949 | 15394301 | Yes |
375 | 2845 | 2845.0 | 109.51 | 109.5 | Modeling valuations for EuroQol health states. | P Dolan | Med Care | 1997 | 9366889 | Yes |
376 | 2843 | 2843.0 | 0.0 | 0.0 | Estimation of average heterozygosity and genetic distance from a small number of individuals. | M Nei | Genetics | 1978 | 17248844 | Yes |
377 | 8529 | 2843.0 | 398.26 | 132.8 | Cancer statistics, 2012. | Rebecca Siegel, Deepa Naishadham, Ahmedin Jemal | CA Cancer J Clin | 2012 | 22237781 | Yes |
378 | 11355 | 2838.8 | 524.05 | 131.0 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | Ann Intern Med | 2009 | 19622511 | No |
379 | 2829 | 2829.0 | 110.14 | 110.1 | Prejudice, social stress, and mental health in lesbian, gay, and bisexual populations: conceptual issues and research evidence. | Ilan H Meyer | Psychol Bull | 2003 | 12956539 | No |
380 | 2827 | 2827.0 | 0.0 | 0.0 | Weighted kappa: nominal scale agreement with provision for scaled disagreement or partial credit. | J Cohen | Psychol Bull | 1968 | 19673146 | Yes |
381 | 2818 | 2818.0 | 79.45 | 79.5 | ras genes. | M Barbacid | Annu Rev Biochem | 1987 | 3304147 | No |
382 | 8451 | 2817.0 | 0.0 | 0.0 | Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. | J F Kerr, A H Wyllie, A R Currie | Br J Cancer | 1972 | 4561027 | No |
383 | 5607 | 2803.5 | 263.22 | 131.6 | The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay. | I F Benzie, J J Strain | Anal Biochem | 1996 | 8660627 | Yes |
384 | 2802 | 2802.0 | 119.68 | 119.7 | Tissue destruction by neutrophils. | S J Weiss | N Engl J Med | 1989 | 2536474 | No |
385 | 2794 | 2794.0 | 82.5 | 82.5 | A catalogue of splice junction sequences. | S M Mount | Nucleic Acids Res | 1982 | 7063411 | Yes |
386 | 2787 | 2787.0 | 0.0 | 0.0 | Generalized expectancies for internal versus external control of reinforcement. | J B Rotter | Psychol Monogr | 1966 | 5340840 | No |
387 | 5570 | 2785.0 | 230.94 | 115.5 | Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. | Laurent Excoffier, Heidi E L Lischer | Mol Ecol Resour | 2010 | 21565059 | Yes |
388 | 2781 | 2781.0 | 95.46 | 95.5 | Graphene: status and prospects. | A K Geim | Science | 2009 | 19541989 | Yes |
389 | 2778 | 2778.0 | 82.56 | 82.6 | Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? | Kim A Brogden | Nat Rev Microbiol | 2005 | 15703760 | No |
390 | 5546 | 2773.0 | 178.59 | 89.3 | Balanced basis sets of split valence, triple zeta valence and quadruple zeta valence quality for H to Rn: Design and assessment of accuracy. | Florian Weigend, Reinhart Ahlrichs | Phys Chem Chem Phys | 2005 | 16240044 | Yes |
391 | 5538 | 2769.0 | 162.0 | 81.0 | The basics of epithelial-mesenchymal transition. | Raghu Kalluri, Robert A Weinberg | J Clin Invest | 2009 | 19487818 | No |
392 | 5538 | 2769.0 | 180.46 | 90.2 | ESTIMATING F-STATISTICS FOR THE ANALYSIS OF POPULATION STRUCTURE. | B S Weir, C Clark Cockerham | Evolution | 1984 | 28563791 | Yes |
393 | 2767 | 2767.0 | 78.01 | 78.0 | The basis of anisotropic water diffusion in the nervous system - a technical review. | Christian Beaulieu | NMR Biomed | 2002 | 12489094 | No |
394 | 2760 | 2760.0 | 0.0 | 0.0 | The determination of enzyme inhibitor constants. | M DIXON | Biochem J | 1953 | 13093635 | Yes |
395 | 2759 | 2759.0 | 102.02 | 102.0 | Development of a classification system for periodontal diseases and conditions. | G C Armitage | Ann Periodontol | 1999 | 10863370 | No |
396 | 2749 | 2749.0 | 0.0 | 0.0 | Aggregation of blood platelets by adenosine diphosphate and its reversal. | G V BORN | Nature | 1962 | 13871375 | Yes |
397 | 2748 | 2748.0 | 80.52 | 80.5 | The origins and the future of microfluidics. | George M Whitesides | Nature | 2006 | 16871203 | No |
398 | 5493 | 2746.5 | 111.5 | 55.8 | The ubiquitin system. | A Hershko, A Ciechanover | Annu Rev Biochem | 1998 | 9759494 | No |
399 | 2745 | 2745.0 | 97.25 | 97.2 | Soft self-consistent pseudopotentials in a generalized eigenvalue formalism. | Vanderbilt | Phys Rev B Condens Matter | 1990 | 9993096 | Yes |
400 | 2739 | 2739.0 | 97.97 | 98.0 | Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans. | L R Squire | Psychol Rev | 1992 | 1594723 | No |
401 | 13683 | 2736.6 | 513.11 | 102.6 | Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. | O P Hamill, A Marty, E Neher, B Sakmann, F J Sigworth | Pflugers Arch | 1981 | 6270629 | Yes |
402 | 5472 | 2736.0 | 140.24 | 70.1 | Inference of macromolecular assemblies from crystalline state. | Evgeny Krissinel, Kim Henrick | J Mol Biol | 2007 | 17681537 | Yes |
403 | 5461 | 2730.5 | 176.37 | 88.2 | Ab initio molecular dynamics for liquid metals. | Kresse, Hafner | Phys Rev B Condens Matter | 1993 | 10004490 | Yes |
404 | 2728 | 2728.0 | 65.29 | 65.3 | Activators and target genes of Rel/NF-kappaB transcription factors. | H L Pahl | Oncogene | 1999 | 10602461 | No |
405 | 2723 | 2723.0 | 0.0 | 0.0 | Observational study of behavior: sampling methods. | J Altmann | Behaviour | 1974 | 4597405 | No |
406 | 8149 | 2716.3 | 176.77 | 58.9 | Significance analysis of microarrays applied to the ionizing radiation response. | V G Tusher, R Tibshirani, G Chu | Proc Natl Acad Sci U S A | 2001 | 11309499 | Yes |
407 | 8141 | 2713.7 | 404.08 | 134.7 | A global measure of perceived stress. | S Cohen, T Kamarck, R Mermelstein | J Health Soc Behav | 1983 | 6668417 | Yes |
408 | 2711 | 2711.0 | 94.84 | 94.8 | Integrins: a family of cell surface receptors. | R O Hynes | Cell | 1987 | 3028640 | No |
409 | 2705 | 2705.0 | 112.09 | 112.1 | Silver stain for proteins in polyacrylamide gels: a modified procedure with enhanced uniform sensitivity. | J H Morrissey | Anal Biochem | 1981 | 6172996 | Yes |
410 | 2701 | 2701.0 | 93.3 | 93.3 | Biological roles of oligosaccharides: all of the theories are correct. | A Varki | Glycobiology | 1993 | 8490246 | No |
411 | 2695 | 2695.0 | 77.22 | 77.2 | How do you feel? Interoception: the sense of the physiological condition of the body. | A D Craig | Nat Rev Neurosci | 2002 | 12154366 | No |
412 | 2695 | 2695.0 | 0.0 | 0.0 | Staining of tissue sections for electron microscopy with heavy metals. | M L WATSON | J Biophys Biochem Cytol | 1958 | 13563554 | Yes |
413 | 8059 | 2686.3 | 182.37 | 60.8 | Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. | Benjamin P Lewis, Christopher B Burge, David P Bartel | Cell | 2005 | 15652477 | Yes |
414 | 2682 | 2682.0 | 93.77 | 93.8 | Functions of DNA methylation: islands, start sites, gene bodies and beyond. | Peter A Jones | Nat Rev Genet | 2012 | 22641018 | No |
415 | 2681 | 2681.0 | 59.45 | 59.5 | STATs and gene regulation. | J E Darnell | Science | 1997 | 9287210 | No |
416 | 2674 | 2674.0 | 54.53 | 54.5 | Cell signaling by receptor tyrosine kinases. | J Schlessinger | Cell | 2000 | 11057895 | No |
417 | 2671 | 2671.0 | 77.46 | 77.5 | Free R value: a novel statistical quantity for assessing the accuracy of crystal structures. | A T Brünger | Nature | 1992 | 18481394 | Yes |
418 | 2668 | 2668.0 | 0.0 | 0.0 | Basic principles of ROC analysis. | C E Metz | Semin Nucl Med | 1978 | 112681 | Yes |
419 | 2658 | 2658.0 | 76.51 | 76.5 | Neural networks and physical systems with emergent collective computational abilities. | J J Hopfield | Proc Natl Acad Sci U S A | 1982 | 6953413 | Yes |
420 | 2657 | 2657.0 | 71.68 | 71.7 | Wound healing--aiming for perfect skin regeneration. | P Martin | Science | 1997 | 9082989 | No |
421 | 5303 | 2651.5 | 224.59 | 112.3 | Management of hepatocellular carcinoma: an update. | Jordi Bruix, Morris Sherman | Hepatology | 2011 | 21374666 | No |
422 | 5301 | 2650.5 | 139.84 | 69.9 | The plant immune system. | Jonathan D G Jones, Jeffery L Dangl | Nature | 2006 | 17108957 | No |
423 | 10550 | 2637.5 | 284.54 | 71.1 | Haploview: analysis and visualization of LD and haplotype maps. | J C Barrett, B Fry, J Maller, M J Daly | Bioinformatics | 2005 | 15297300 | Yes |
424 | 2637 | 2637.0 | 61.17 | 61.2 | Somatic generation of antibody diversity. | S Tonegawa | Nature | 1983 | 6300689 | No |
425 | 5271 | 2635.5 | 124.49 | 62.2 | Toll-like receptor signalling. | Shizuo Akira, Kiyoshi Takeda | Nat Rev Immunol | 2004 | 15229469 | No |
426 | 2635 | 2635.0 | 76.16 | 76.2 | The pathobiology of diabetic complications: a unifying mechanism. | Michael Brownlee | Diabetes | 2005 | 15919781 | No |
427 | 5266 | 2633.0 | 0.0 | 0.0 | Preparation of iodine-131 labelled human growth hormone of high specific activity. | W M HUNTER, F C GREENWOOD | Nature | 1962 | 14450081 | Yes |
428 | 2632 | 2632.0 | 70.28 | 70.3 | The scanning model for translation: an update. | M Kozak | J Cell Biol | 1989 | 2645293 | No |
429 | 2626 | 2626.0 | 101.95 | 102.0 | Emerging adulthood. A theory of development from the late teens through the twenties. | J J Arnett | Am Psychol | 2000 | 10842426 | Yes |
430 | 2611 | 2611.0 | 84.15 | 84.2 | EEG alpha and theta oscillations reflect cognitive and memory performance: a review and analysis. | W Klimesch | Brain Res Brain Res Rev | 1999 | 10209231 | No |
431 | 7833 | 2611.0 | 215.56 | 71.9 | Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. | Da Wei Huang, Brad T Sherman, Richard A Lempicki | Nucleic Acids Res | 2009 | 19033363 | Yes |
432 | 7824 | 2608.0 | 0.0 | 0.0 | Determination of serum proteins by means of the biuret reaction. | A G GORNALL, C J BARDAWILL, M M DAVID | J Biol Chem | 1949 | 18110453 | Yes |
433 | 2604 | 2604.0 | 56.33 | 56.3 | The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. | Isaiah J Fidler | Nat Rev Cancer | 2003 | 12778135 | No |
434 | 2604 | 2604.0 | 0.0 | 0.0 | The colorimetric estimation of formaldehyde by means of the Hantzsch reaction. | T NASH | Biochem J | 1953 | 13105648 | Yes |
435 | 2596 | 2596.0 | 80.26 | 80.3 | Statistical tests of neutrality of mutations against population growth, hitchhiking and background selection. | Y X Fu | Genetics | 1997 | 9335623 | Yes |
436 | 5188 | 2594.0 | 127.59 | 63.8 | MicroRNA signatures in human cancers. | George A Calin, Carlo M Croce | Nat Rev Cancer | 2006 | 17060945 | No |
437 | 2592 | 2592.0 | 81.53 | 81.5 | Hay fever, hygiene, and household size. | D P Strachan | BMJ | 1989 | 2513902 | Yes |
438 | 2590 | 2590.0 | 131.42 | 131.4 | Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. | O W Griffith | Anal Biochem | 1980 | 7416462 | Yes |
439 | 18067 | 2581.0 | 441.22 | 63.0 | UCSF Chimera--a visualization system for exploratory research and analysis. | Eric F Pettersen, Thomas D Goddard, Conrad C Huang, Gregory S Couch, Daniel M Greenblatt, Elaine C Meng, Thomas E Ferrin | J Comput Chem | 2004 | 15264254 | Yes |
440 | 5157 | 2578.5 | 124.48 | 62.2 | Angiogenesis in cancer and other diseases. | P Carmeliet, R K Jain | Nature | 2000 | 11001068 | No |
441 | 10307 | 2576.8 | 288.53 | 72.1 | Improved methods for building protein models in electron density maps and the location of errors in these models. | T A Jones, J Y Zou, S W Cowan, M Kjeldgaard | Acta Crystallogr A | 1991 | 2025413 | Yes |
442 | 2576 | 2576.0 | 65.39 | 65.4 | Folding DNA to create nanoscale shapes and patterns. | Paul W K Rothemund | Nature | 2006 | 16541064 | Yes |
443 | 2575 | 2575.0 | 72.6 | 72.6 | WHAT IF: a molecular modeling and drug design program. | G Vriend | J Mol Graph | 1990 | 2268628 | Yes |
444 | 2567 | 2567.0 | 104.66 | 104.7 | Nitric oxide as a secretory product of mammalian cells. | C Nathan | FASEB J | 1992 | 1381691 | No |
445 | 2566 | 2566.0 | 0.0 | 0.0 | [A micro-method of immuno-electrophoresis]. | J J SCHEIDEGGER | Int Arch Allergy Appl Immunol | 1955 | 13262900 | Yes |
446 | 5117 | 2558.5 | 0.0 | 0.0 | Receptive fields, binocular interaction and functional architecture in the cat's visual cortex. | D H HUBEL, T N WIESEL | J Physiol | 1962 | 14449617 | Yes |
447 | 2555 | 2555.0 | 67.75 | 67.8 | Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. | Ting-Chao Chou | Pharmacol Rev | 2006 | 16968952 | No |
448 | 5104 | 2552.0 | 128.97 | 64.5 | WGCNA: an R package for weighted correlation network analysis. | Peter Langfelder, Steve Horvath | BMC Bioinformatics | 2008 | 19114008 | Yes |
449 | 2551 | 2551.0 | 78.57 | 78.6 | Mesenchymal stem cells. | A I Caplan | J Orthop Res | 1991 | 1870029 | Yes |
450 | 2547 | 2547.0 | 73.15 | 73.2 | Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs. | M Kozak | Nucleic Acids Res | 1984 | 6694911 | Yes |
451 | 2542 | 2542.0 | 78.0 | 78.0 | The heat-shock response. | S Lindquist | Annu Rev Biochem | 1986 | 2427013 | No |
452 | 2541 | 2541.0 | 63.98 | 64.0 | Tolerance, danger, and the extended family. | P Matzinger | Annu Rev Immunol | 1994 | 8011301 | No |
453 | 2538 | 2538.0 | 85.19 | 85.2 | Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. | R W Mahley | Science | 1988 | 3283935 | No |
454 | 2536 | 2536.0 | 0.0 | 0.0 | The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. | J F WOESSNER | Arch Biochem Biophys | 1961 | 13786180 | Yes |
455 | 2534 | 2534.0 | 65.31 | 65.3 | Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. | H F Dvorak | N Engl J Med | 1986 | 3537791 | No |
456 | 5064 | 2532.0 | 147.36 | 73.7 | Voxel-based morphometry--the methods. | J Ashburner, K J Friston | Neuroimage | 2000 | 10860804 | No |
457 | 5045 | 2522.5 | 94.16 | 47.1 | The language of covalent histone modifications. | B D Strahl, C D Allis | Nature | 2000 | 10638745 | Yes |
458 | 2519 | 2519.0 | 90.25 | 90.2 | Hepatocellular carcinoma. | Hashem B El-Serag | N Engl J Med | 2011 | 21992124 | No |
459 | 7548 | 2516.0 | 197.72 | 65.9 | TopHat: discovering splice junctions with RNA-Seq. | Cole Trapnell, Lior Pachter, Steven L Salzberg | Bioinformatics | 2009 | 19289445 | Yes |
460 | 2513 | 2513.0 | 60.18 | 60.2 | Angiogenesis in health and disease. | Peter Carmeliet | Nat Med | 2003 | 12778163 | No |
461 | 2504 | 2504.0 | 58.99 | 59.0 | Protein folding and misfolding. | Christopher M Dobson | Nature | 2003 | 14685248 | No |
462 | 2503 | 2503.0 | 94.91 | 94.9 | Health promotion by social cognitive means. | Albert Bandura | Health Educ Behav | 2004 | 15090118 | Yes |
463 | 2499 | 2499.0 | 56.86 | 56.9 | Alzheimer's disease is a synaptic failure. | Dennis J Selkoe | Science | 2002 | 12399581 | No |
464 | 2498 | 2498.0 | 60.31 | 60.3 | Cardiac excitation-contraction coupling. | Donald M Bers | Nature | 2002 | 11805843 | No |
465 | 4995 | 2497.5 | 0.0 | 0.0 | Human malaria parasites in continuous culture. | W Trager, J B Jensen | Science | 1976 | 781840 | Yes |
466 | 2489 | 2489.0 | 95.99 | 96.0 | No adjustments are needed for multiple comparisons. | K J Rothman | Epidemiology | 1990 | 2081237 | Yes |
467 | 2483 | 2483.0 | 73.15 | 73.2 | Biologic basis for interleukin-1 in disease. | C A Dinarello | Blood | 1996 | 8630372 | No |
468 | 9925 | 2481.2 | 377.34 | 94.3 | Cancer statistics, 2010. | Ahmedin Jemal, Rebecca Siegel, Jiaquan Xu, Elizabeth Ward | CA Cancer J Clin | 2010 | 20610543 | Yes |
469 | 2477 | 2477.0 | 50.69 | 50.7 | RNA interference. | Gregory J Hannon | Nature | 2002 | 12110901 | No |
470 | 2474 | 2474.0 | 0.0 | 0.0 | DISC ELECTROPHORESIS. I. BACKGROUND AND THEORY. | L ORNSTEIN | Ann N Y Acad Sci | 1964 | 14240533 | Yes |
471 | 4941 | 2470.5 | 156.72 | 78.4 | Projections of global mortality and burden of disease from 2002 to 2030. | Colin D Mathers, Dejan Loncar | PLoS Med | 2006 | 17132052 | Yes |
472 | 2468 | 2468.0 | 59.37 | 59.4 | Mechanisms of angiogenesis and arteriogenesis. | P Carmeliet | Nat Med | 2000 | 10742145 | No |
473 | 2466 | 2466.0 | 0.0 | 0.0 | Stereotaxic mapping of the monoamine pathways in the rat brain. | U Ungerstedt | Acta Physiol Scand Suppl | 1971 | 4109331 | Yes |
474 | 7393 | 2464.3 | 217.68 | 72.6 | MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment. | Sudhir Kumar, Koichiro Tamura, Masatoshi Nei | Brief Bioinform | 2004 | 15260895 | Yes |
475 | 2464 | 2464.0 | 154.09 | 154.1 | Executive functions. | Adele Diamond | Annu Rev Psychol | 2013 | 23020641 | No |
476 | 2460 | 2460.0 | 78.29 | 78.3 | Non-coding RNAs in human disease. | Manel Esteller | Nat Rev Genet | 2011 | 22094949 | No |
477 | 4913 | 2456.5 | 120.11 | 60.1 | Oncomirs - microRNAs with a role in cancer. | Aurora Esquela-Kerscher, Frank J Slack | Nat Rev Cancer | 2006 | 16557279 | No |
478 | 4912 | 2456.0 | 110.62 | 55.3 | Emergence of scaling in random networks | Barabasi, Albert | Science | 1999 | 10521342 | Yes |
479 | 2455 | 2455.0 | 0.0 | 0.0 | Spectroscopic determination of tryptophan and tyrosine in proteins. | H Edelhoch | Biochemistry | 1967 | 6049437 | Yes |
480 | 2451 | 2451.0 | 66.78 | 66.8 | Obesity as a medical problem. | P G Kopelman | Nature | 2000 | 10766250 | No |
481 | 4901 | 2450.5 | 166.6 | 83.3 | "A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum. | A P Feinberg, B Vogelstein | Anal Biochem | 1984 | 6329026 | Yes |
482 | 2450 | 2450.0 | 50.22 | 50.2 | Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and lamm equation modeling. | P Schuck | Biophys J | 2000 | 10692345 | Yes |
483 | 2449 | 2449.0 | 0.0 | 0.0 | Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. | J D Rowley | Nature | 1973 | 4126434 | Yes |
484 | 4897 | 2448.5 | 161.16 | 80.6 | Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. | S Duval, R Tweedie | Biometrics | 2000 | 10877304 | Yes |
485 | 2448 | 2448.0 | 90.01 | 90.0 | Expert committee recommendations regarding the prevention, assessment, and treatment of child and adolescent overweight and obesity: summary report. | Sarah E Barlow | Pediatrics | 2007 | 18055651 | Yes |
486 | 2447 | 2447.0 | 76.96 | 77.0 | Drug combination studies and their synergy quantification using the Chou-Talalay method. | Ting-Chao Chou | Cancer Res | 2010 | 20068163 | Yes |
487 | 2446 | 2446.0 | 75.4 | 75.4 | Optimal two-stage designs for phase II clinical trials. | R Simon | Control Clin Trials | 1989 | 2702835 | Yes |
488 | 2444 | 2444.0 | 59.4 | 59.4 | Inflammatory bowel disease. | Daniel K Podolsky | N Engl J Med | 2002 | 12167685 | No |
489 | 2434 | 2434.0 | 53.14 | 53.1 | Toll-like receptors and innate immunity. | R Medzhitov | Nat Rev Immunol | 2001 | 11905821 | No |
490 | 2434 | 2434.0 | 0.0 | 0.0 | Statistical estimations in enzyme kinetics. | G N WILKINSON | Biochem J | 1961 | 13785321 | Yes |
491 | 2433 | 2433.0 | 62.21 | 62.2 | CpG-rich islands and the function of DNA methylation. | A P Bird | Nature | 1986 | 2423876 | No |
492 | 7298 | 2432.7 | 1776.81 | 592.3 | Cancer statistics, 2019. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2019 | 30620402 | Yes |
493 | 2430 | 2430.0 | 62.96 | 63.0 | Mitochondrial formation of reactive oxygen species. | Julio F Turrens | J Physiol | 2003 | 14561818 | No |
494 | 4847 | 2423.5 | 132.0 | 66.0 | Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. | C Tuerk, L Gold | Science | 1990 | 2200121 | Yes |
495 | 2418 | 2418.0 | 103.32 | 103.3 | Inositol trisphosphate and diacylglycerol as second messengers. | M J Berridge | Biochem J | 1984 | 6146314 | No |
496 | 2414 | 2414.0 | 66.81 | 66.8 | Chemokines--chemotactic cytokines that mediate inflammation. | A D Luster | N Engl J Med | 1998 | 9459648 | No |
497 | 4826 | 2413.0 | 136.79 | 68.4 | Fast and accurate long-read alignment with Burrows-Wheeler transform. | Heng Li, Richard Durbin | Bioinformatics | 2010 | 20080505 | Yes |
498 | 4821 | 2410.5 | 0.0 | 0.0 | The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique. | R C Graham, M J Karnovsky | J Histochem Cytochem | 1966 | 5962951 | Yes |
499 | 4801 | 2400.5 | 0.0 | 0.0 | A new method for sequencing DNA. | A M Maxam, W Gilbert | Proc Natl Acad Sci U S A | 1977 | 265521 | Yes |
500 | 4797 | 2398.5 | 152.18 | 76.1 | TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. | T R Mosmann, R L Coffman | Annu Rev Immunol | 1989 | 2523712 | No |
501 | 7186 | 2395.3 | 374.48 | 124.8 | HTSeq--a Python framework to work with high-throughput sequencing data. | Simon Anders, Paul Theodor Pyl, Wolfgang Huber | Bioinformatics | 2015 | 25260700 | Yes |
502 | 2385 | 2385.0 | 55.46 | 55.5 | One-step gene disruption in yeast. | R J Rothstein | Methods Enzymol | 1983 | 6310324 | Yes |
503 | 2384 | 2384.0 | 84.24 | 84.2 | Room-Temperature Ionic Liquids. Solvents for Synthesis and Catalysis. | Thomas Welton | Chem Rev | 1999 | 11849019 | Yes |
504 | 4766 | 2383.0 | 0.0 | 0.0 | Superoxide dismutase: improved assays and an assay applicable to acrylamide gels. | C Beauchamp, I Fridovich | Anal Biochem | 1971 | 4943714 | Yes |
505 | 2377 | 2377.0 | 65.83 | 65.8 | Origin and physiological roles of inflammation. | Ruslan Medzhitov | Nature | 2008 | 18650913 | No |
506 | 2371 | 2371.0 | 57.9 | 57.9 | TGFbeta in Cancer. | Joan Massagué | Cell | 2008 | 18662538 | No |
507 | 2369 | 2369.0 | 107.55 | 107.5 | Half a century of research on the Stroop effect: an integrative review. | C M MacLeod | Psychol Bull | 1991 | 2034749 | No |
508 | 7105 | 2368.3 | 203.62 | 67.9 | Understanding the Warburg effect: the metabolic requirements of cell proliferation. | Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson | Science | 2009 | 19460998 | No |
509 | 2367 | 2367.0 | 92.28 | 92.3 | Psychometric properties of the strengths and difficulties questionnaire. | R Goodman | J Am Acad Child Adolesc Psychiatry | 2001 | 11699809 | Yes |
510 | 2366 | 2366.0 | 64.58 | 64.6 | Photoelectrochemical cells. | M Grätzel | Nature | 2001 | 11713540 | Yes |
511 | 2363 | 2363.0 | 124.64 | 124.6 | Adolescence-limited and life-course-persistent antisocial behavior: a developmental taxonomy. | T E Moffitt | Psychol Rev | 1993 | 8255953 | No |
512 | 2362 | 2362.0 | 85.92 | 85.9 | Estimation of metabolite concentrations from localized in vivo proton NMR spectra. | S W Provencher | Magn Reson Med | 1993 | 8139448 | Yes |
513 | 2361 | 2361.0 | 52.38 | 52.4 | Interleukin-12 and the regulation of innate resistance and adaptive immunity. | Giorgio Trinchieri | Nat Rev Immunol | 2003 | 12563297 | No |
514 | 4720 | 2360.0 | 2360.0 | 1180.0 | Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. | Zunyou Wu, Jennifer M McGoogan | JAMA | 2020 | 32091533 | Yes |
515 | 2359 | 2359.0 | 76.25 | 76.2 | Phase separation of integral membrane proteins in Triton X-114 solution. | C Bordier | J Biol Chem | 1981 | 6257680 | Yes |
516 | 7072 | 2357.3 | 278.49 | 92.8 | Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. | R A Deyo, D C Cherkin, M A Ciol | J Clin Epidemiol | 1992 | 1607900 | Yes |
517 | 2355 | 2355.0 | 47.4 | 47.4 | Genome maintenance mechanisms for preventing cancer. | J H Hoeijmakers | Nature | 2001 | 11357144 | No |
518 | 2355 | 2355.0 | 0.0 | 0.0 | The magical number seven plus or minus two: some limits on our capacity for processing information. | G A MILLER | Psychol Rev | 1956 | 13310704 | Yes |
519 | 4707 | 2353.5 | 178.12 | 89.1 | The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers. | J Vieira, J Messing | Gene | 1982 | 6295879 | Yes |
520 | 2353 | 2353.0 | 56.75 | 56.8 | Nuclear factor-kappaB in cancer development and progression. | Michael Karin | Nature | 2006 | 16724054 | No |
521 | 9401 | 2350.2 | 217.0 | 54.2 | Cluster analysis and display of genome-wide expression patterns. | M B Eisen, P T Spellman, P O Brown, D Botstein | Proc Natl Acad Sci U S A | 1998 | 9843981 | Yes |
522 | 2347 | 2347.0 | 41.79 | 41.8 | Mechanisms underlying ubiquitination. | C M Pickart | Annu Rev Biochem | 2001 | 11395416 | No |
523 | 4690 | 2345.0 | 170.76 | 85.4 | mTOR signaling in growth control and disease. | Mathieu Laplante, David M Sabatini | Cell | 2012 | 22500797 | No |
524 | 9370 | 2342.5 | 421.84 | 105.5 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | BMJ | 2009 | 19622551 | No |
525 | 4683 | 2341.5 | 195.66 | 97.8 | Measuring agreement in method comparison studies. | J M Bland, D G Altman | Stat Methods Med Res | 1999 | 10501650 | No |
526 | 4677 | 2338.5 | 118.38 | 59.2 | Oxidants, oxidative stress and the biology of ageing. | T Finkel, N J Holbrook | Nature | 2000 | 11089981 | No |
527 | 2338 | 2338.0 | 50.11 | 50.1 | Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. | Shimon Sakaguchi | Annu Rev Immunol | 2004 | 15032588 | No |
528 | 2337 | 2337.0 | 76.91 | 76.9 | ABC transporters: from microorganisms to man. | C F Higgins | Annu Rev Cell Biol | 1992 | 1282354 | No |
529 | 2334 | 2334.0 | 67.96 | 68.0 | Recent advances with liposomes as pharmaceutical carriers. | Vladimir P Torchilin | Nat Rev Drug Discov | 2005 | 15688077 | No |
530 | 2332 | 2332.0 | 0.0 | 0.0 | Estimation of the molecular weights of proteins by Sephadex gel-filtration. | P Andrews | Biochem J | 1964 | 4158310 | Yes |
531 | 2328 | 2328.0 | 129.62 | 129.6 | The short-form McGill Pain Questionnaire. | Ronald Melzack | Pain | 1987 | 3670870 | Yes |
532 | 4652 | 2326.0 | 178.56 | 89.3 | Tissue engineering. | R Langer, J P Vacanti | Science | 1993 | 8493529 | No |
533 | 2326 | 2326.0 | 95.09 | 95.1 | Essential oils: their antibacterial properties and potential applications in foods--a review. | Sara Burt | Int J Food Microbiol | 2004 | 15246235 | No |
534 | 2323 | 2323.0 | 0.0 | 0.0 | The glomerular permeability determined by dextran clearance using Sephadex gel filtration. | C E Mogensen | Scand J Clin Lab Invest | 1968 | 5637478 | Yes |
535 | 2319 | 2319.0 | 0.0 | 0.0 | Perceived exertion as an indicator of somatic stress. | G Borg | Scand J Rehabil Med | 1970 | 5523831 | Yes |
536 | 20809 | 2312.1 | 595.93 | 66.2 | The Sequence Alignment/Map format and SAMtools. | Heng Li, Bob Handsaker, Alec Wysoker, Tim Fennell, Jue Ruan, Nils Homer, Gabor Marth, Goncalo Abecasis, Richard Durbin | Bioinformatics | 2009 | 19505943 | Yes |
537 | 2311 | 2311.0 | 51.71 | 51.7 | Papillomaviruses and cancer: from basic studies to clinical application. | Harald zur Hausen | Nat Rev Cancer | 2002 | 12044010 | No |
538 | 2308 | 2308.0 | 61.2 | 61.2 | Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. | S A Bustin | J Mol Endocrinol | 2000 | 11013345 | No |
539 | 4612 | 2306.0 | 144.71 | 72.4 | The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. | Taro Kawai, Shizuo Akira | Nat Immunol | 2010 | 20404851 | No |
540 | 2304 | 2304.0 | 67.64 | 67.6 | Predictive reward signal of dopamine neurons. | W Schultz | J Neurophysiol | 1998 | 9658025 | No |
541 | 6896 | 2298.7 | 220.72 | 73.6 | Detecting the number of clusters of individuals using the software STRUCTURE: a simulation study. | G Evanno, S Regnaut, J Goudet | Mol Ecol | 2005 | 15969739 | Yes |
542 | 4591 | 2295.5 | 132.03 | 66.0 | Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. | T C Chou, P Talalay | Adv Enzyme Regul | 1984 | 6382953 | Yes |
543 | 4585 | 2292.5 | 176.87 | 88.4 | Computed tomography--an increasing source of radiation exposure. | David J Brenner, Eric J Hall | N Engl J Med | 2007 | 18046031 | No |
544 | 9167 | 2291.8 | 458.15 | 114.5 | APACHE II: a severity of disease classification system. | W A Knaus, E A Draper, D P Wagner, J E Zimmerman | Crit Care Med | 1985 | 3928249 | Yes |
545 | 6864 | 2288.0 | 165.36 | 55.1 | The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. | R C Lee, R L Feinbaum, V Ambros | Cell | 1993 | 8252621 | Yes |
546 | 4575 | 2287.5 | 171.91 | 86.0 | The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. | Stephen B Edge, Carolyn C Compton | Ann Surg Oncol | 2010 | 20180029 | No |
547 | 4574 | 2287.0 | 120.94 | 60.5 | Caspases: enemies within. | N A Thornberry, Y Lazebnik | Science | 1998 | 9721091 | No |
548 | 2286 | 2286.0 | 49.84 | 49.8 | The danger model: a renewed sense of self. | Polly Matzinger | Science | 2002 | 11951032 | Yes |
549 | 2285 | 2285.0 | 60.73 | 60.7 | Molecular chaperones in cellular protein folding. | F U Hartl | Nature | 1996 | 8637592 | No |
550 | 2282 | 2282.0 | 0.0 | 0.0 | A gene complex controlling segmentation in Drosophila. | E B Lewis | Nature | 1978 | 103000 | Yes |
551 | 4564 | 2282.0 | 108.84 | 54.4 | Establishment in culture of pluripotential cells from mouse embryos. | M J Evans, M H Kaufman | Nature | 1981 | 7242681 | Yes |
552 | 2280 | 2280.0 | 94.23 | 94.2 | The processing-speed theory of adult age differences in cognition. | T A Salthouse | Psychol Rev | 1996 | 8759042 | No |
553 | 4559 | 2279.5 | 125.85 | 62.9 | Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. | D B Smith, K S Johnson | Gene | 1988 | 3047011 | Yes |
554 | 2275 | 2275.0 | 0.0 | 0.0 | Gene action in the X-chromosome of the mouse (Mus musculus L.). | M F LYON | Nature | 1961 | 13764598 | Yes |
555 | 4548 | 2274.0 | 0.0 | 0.0 | Assessment of outcome after severe brain damage. | B Jennett, M Bond | Lancet | 1975 | 46957 | Yes |
556 | 4542 | 2271.0 | 100.38 | 50.2 | Innate immune recognition. | Charles A Janeway, Ruslan Medzhitov | Annu Rev Immunol | 2002 | 11861602 | No |
557 | 4538 | 2269.0 | 0.0 | 0.0 | A simplified method of evaluating dose-effect experiments. | J T LITCHFIELD, F WILCOXON | J Pharmacol Exp Ther | 1949 | 18152921 | Yes |
558 | 2266 | 2266.0 | 64.46 | 64.5 | The genetic legacy of the Quaternary ice ages. | G Hewitt | Nature | 2000 | 10879524 | No |
559 | 4525 | 2262.5 | 0.0 | 0.0 | Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose. | H Aviv, P Leder | Proc Natl Acad Sci U S A | 1972 | 4504350 | Yes |
560 | 4521 | 2260.5 | 125.86 | 62.9 | In vitro selection of RNA molecules that bind specific ligands. | A D Ellington, J W Szostak | Nature | 1990 | 1697402 | Yes |
561 | 4517 | 2258.5 | 126.33 | 63.2 | Exploring the full spectrum of macrophage activation. | David M Mosser, Justin P Edwards | Nat Rev Immunol | 2008 | 19029990 | No |
562 | 4515 | 2257.5 | 0.0 | 0.0 | PERIODONTAL DISEASE IN PREGNANCY. II. CORRELATION BETWEEN ORAL HYGIENE AND PERIODONTAL CONDTION. | J SILNESS, H LOE | Acta Odontol Scand | 1964 | 14158464 | Yes |
563 | 2254 | 2254.0 | 63.36 | 63.4 | Cadherin cell adhesion receptors as a morphogenetic regulator. | M Takeichi | Science | 1991 | 2006419 | No |
564 | 4492 | 2246.0 | 152.81 | 76.4 | Complex brain networks: graph theoretical analysis of structural and functional systems. | Ed Bullmore, Olaf Sporns | Nat Rev Neurosci | 2009 | 19190637 | No |
565 | 2243 | 2243.0 | 58.9 | 58.9 | Memory--a century of consolidation. | J L McGaugh | Science | 2000 | 10634773 | No |
566 | 2242 | 2242.0 | 0.0 | 0.0 | Analysis of gene diversity in subdivided populations. | M Nei | Proc Natl Acad Sci U S A | 1973 | 4519626 | Yes |
567 | 11208 | 2241.6 | 521.96 | 104.4 | The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. | D J Buysse, C F Reynolds, T H Monk, S R Berman, D J Kupfer | Psychiatry Res | 1989 | 2748771 | Yes |
568 | 6713 | 2237.7 | 234.03 | 78.0 | Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. | Y Gavrieli, Y Sherman, S A Ben-Sasson | J Cell Biol | 1992 | 1400587 | Yes |
569 | 2237 | 2237.0 | 56.5 | 56.5 | Cell adhesion: the molecular basis of tissue architecture and morphogenesis. | B M Gumbiner | Cell | 1996 | 8608588 | No |
570 | 2235 | 2235.0 | 76.63 | 76.6 | Gene regulation by steroid hormones. | M Beato | Cell | 1989 | 2644044 | No |
571 | 13407 | 2234.5 | 577.79 | 96.3 | Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support. | Paul A Harris, Robert Taylor, Robert Thielke, Jonathon Payne, Nathaniel Gonzalez, Jose G Conde | J Biomed Inform | 2009 | 18929686 | Yes |
572 | 2231 | 2231.0 | 0.0 | 0.0 | On the number of segregating sites in genetical models without recombination. | G A Watterson | Theor Popul Biol | 1975 | 1145509 | Yes |
573 | 4449 | 2224.5 | 157.88 | 78.9 | Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees. | K Tamura, M Nei | Mol Biol Evol | 1993 | 8336541 | Yes |
574 | 4441 | 2220.5 | 0.0 | 0.0 | Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. | S Marklund, G Marklund | Eur J Biochem | 1974 | 4215654 | Yes |
575 | 8881 | 2220.2 | 0.0 | 0.0 | Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. | P W Rigby, M Dieckmann, C Rhodes, P Berg | J Mol Biol | 1977 | 881736 | Yes |
576 | 2220 | 2220.0 | 43.68 | 43.7 | Wnt signaling and cancer. | P Polakis | Genes Dev | 2000 | 10921899 | No |
577 | 8880 | 2220.0 | 509.87 | 127.5 | Cancer statistics, 2014. | Rebecca Siegel, Jiemin Ma, Zhaohui Zou, Ahmedin Jemal | CA Cancer J Clin | 2014 | 24399786 | Yes |
578 | 2218 | 2218.0 | 0.0 | 0.0 | Separation of leukocytes from blood and bone marrow. Introduction. | A Böyum | Scand J Clin Lab Invest Suppl | 1968 | 5707208 | Yes |
579 | 2217 | 2217.0 | 64.06 | 64.1 | Cell death during development of the nervous system. | R W Oppenheim | Annu Rev Neurosci | 1991 | 2031577 | No |
580 | 2213 | 2213.0 | 0.0 | 0.0 | Rapid isolation of antigens from cells with a staphylococcal protein A-antibody adsorbent: parameters of the interaction of antibody-antigen complexes with protein A. | S W Kessler | J Immunol | 1975 | 1102604 | Yes |
581 | 2213 | 2213.0 | 53.73 | 53.7 | Salt and drought stress signal transduction in plants. | Jian-Kang Zhu | Annu Rev Plant Biol | 2002 | 12221975 | No |
582 | 6624 | 2208.0 | 171.01 | 57.0 | Pathogen recognition and innate immunity. | Shizuo Akira, Satoshi Uematsu, Osamu Takeuchi | Cell | 2006 | 16497588 | No |
583 | 2202 | 2202.0 | 102.58 | 102.6 | FreeSurfer. | Bruce Fischl | Neuroimage | 2012 | 22248573 | No |
584 | 4398 | 2199.0 | 133.22 | 66.6 | Unified segmentation. | John Ashburner, Karl J Friston | Neuroimage | 2005 | 15955494 | Yes |
585 | 2194 | 2194.0 | 61.13 | 61.1 | The resurgence of platinum-based cancer chemotherapy. | Lloyd Kelland | Nat Rev Cancer | 2007 | 17625587 | No |
586 | 6575 | 2191.7 | 289.22 | 96.4 | Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. | R M Palmer, A G Ferrige, S Moncada | Nature | 1987 | 3495737 | Yes |
587 | 4379 | 2189.5 | 135.54 | 67.8 | Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. | F W Studier, B A Moffatt | J Mol Biol | 1986 | 3537305 | Yes |
588 | 2188 | 2188.0 | 57.01 | 57.0 | Prostaglandins and leukotrienes: advances in eicosanoid biology. | C D Funk | Science | 2001 | 11729303 | No |
589 | 4370 | 2185.0 | 196.68 | 98.3 | Longitudinal data analysis for discrete and continuous outcomes. | S L Zeger, K Y Liang | Biometrics | 1986 | 3719049 | Yes |
590 | 2181 | 2181.0 | 0.0 | 0.0 | Pharmacological implications of microsomal enzyme induction. | A H Conney | Pharmacol Rev | 1967 | 4383307 | Yes |
591 | 4362 | 2181.0 | 0.0 | 0.0 | Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain. | J Glowinski, L L Iversen | J Neurochem | 1966 | 5950056 | Yes |
592 | 2179 | 2179.0 | 78.21 | 78.2 | Primate models of movement disorders of basal ganglia origin. | M R DeLong | Trends Neurosci | 1990 | 1695404 | No |
593 | 2179 | 2179.0 | 0.0 | 0.0 | A relation between non-esterified fatty acids in plasma and the metabolism of glucose. | V P DOLE | J Clin Invest | 1956 | 13286333 | Yes |
594 | 2179 | 2179.0 | 0.0 | 0.0 | [Rapid physiological coagulation method in determination of fibrinogen]. | A CLAUSS | Acta Haematol | 1957 | 13434757 | Yes |
595 | 2176 | 2176.0 | 0.0 | 0.0 | Some factors in the interpretation of protein denaturation. | W KAUZMANN | Adv Protein Chem | 1959 | 14404936 | Yes |
596 | 4351 | 2175.5 | 191.85 | 95.9 | A method of comparing the areas under receiver operating characteristic curves derived from the same cases. | J A Hanley, B J McNeil | Radiology | 1983 | 6878708 | Yes |
597 | 2172 | 2172.0 | 81.44 | 81.4 | Delayed neuronal death in the gerbil hippocampus following ischemia. | T Kirino | Brain Res | 1982 | 7093691 | Yes |
598 | 4341 | 2170.5 | 114.53 | 57.3 | High-efficiency transformation of mammalian cells by plasmid DNA. | C Chen, H Okayama | Mol Cell Biol | 1987 | 3670292 | Yes |
599 | 2169 | 2169.0 | 0.0 | 0.0 | EQUILIBRIUM ULTRACENTRIFUGATION OF DILUTE SOLUTIONS. | D A YPHANTIS | Biochemistry | 1964 | 14155091 | Yes |
600 | 2168 | 2168.0 | 64.2 | 64.2 | Cellular and molecular mechanisms of fibrosis. | T A Wynn | J Pathol | 2008 | 18161745 | No |
601 | 2167 | 2167.0 | 50.43 | 50.4 | Principles of CDK regulation. | D O Morgan | Nature | 1995 | 7877684 | No |
602 | 4327 | 2163.5 | 143.69 | 71.8 | Adherence to medication. | Lars Osterberg, Terrence Blaschke | N Engl J Med | 2005 | 16079372 | No |
603 | 4323 | 2161.5 | 237.14 | 118.6 | GenAlEx 6.5: genetic analysis in Excel. Population genetic software for teaching and research--an update. | Rod Peakall, Peter E Smouse | Bioinformatics | 2012 | 22820204 | Yes |
604 | 8638 | 2159.5 | 315.81 | 79.0 | Establishing a standard definition for child overweight and obesity worldwide: international survey. | T J Cole, M C Bellizzi, K M Flegal, W H Dietz | BMJ | 2000 | 10797032 | Yes |
605 | 4304 | 2152.0 | 94.1 | 47.0 | MicroRNAs: small RNAs with a big role in gene regulation. | Lin He, Gregory J Hannon | Nat Rev Genet | 2004 | 15211354 | No |
606 | 2152 | 2152.0 | 54.28 | 54.3 | Epigenetics in cancer. | Manel Esteller | N Engl J Med | 2008 | 18337604 | No |
607 | 2150 | 2150.0 | 53.05 | 53.0 | Autophagy: process and function. | Noboru Mizushima | Genes Dev | 2007 | 18006683 | No |
608 | 4295 | 2147.5 | 0.0 | 0.0 | Pain mechanisms: a new theory. | R Melzack, P D Wall | Science | 1965 | 5320816 | No |
609 | 2145 | 2145.0 | 0.0 | 0.0 | Models for the specific adhesion of cells to cells. | G I Bell | Science | 1978 | 347575 | No |
610 | 2143 | 2143.0 | 0.0 | 0.0 | Measurement of pain. | E C Huskisson | Lancet | 1974 | 4139420 | Yes |
611 | 2142 | 2142.0 | 68.22 | 68.2 | The transforming growth factor-beta family. | J Massagué | Annu Rev Cell Biol | 1990 | 2177343 | No |
612 | 2133 | 2133.0 | 52.39 | 52.4 | Bone resorption by osteoclasts. | S L Teitelbaum | Science | 2000 | 10968780 | No |
613 | 2128 | 2128.0 | 95.42 | 95.4 | Quantifying test-retest reliability using the intraclass correlation coefficient and the SEM. | Joseph P Weir | J Strength Cond Res | 2005 | 15705040 | No |
614 | 2127 | 2127.0 | 73.33 | 73.3 | Medscape's response to the Institute of Medicine Report: Crossing the quality chasm: a new health system for the 21st century. | M Leavitt | MedGenMed | 2001 | 11549951 | No |
615 | 4254 | 2127.0 | 111.89 | 55.9 | Autophagy in the pathogenesis of disease. | Beth Levine, Guido Kroemer | Cell | 2008 | 18191218 | No |
616 | 2125 | 2125.0 | 0.0 | 0.0 | Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism. | P MITCHELL | Nature | 1961 | 13771349 | Yes |
617 | 4248 | 2124.0 | 99.43 | 49.7 | Inflammation and cancer: back to Virchow? | F Balkwill, A Mantovani | Lancet | 2001 | 11229684 | No |
618 | 4244 | 2122.0 | 0.0 | 0.0 | PERIODONTAL DISEASE IN PREGNANCY. I. PREVALENCE AND SEVERITY. | H LOE, J SILNESS | Acta Odontol Scand | 1963 | 14121956 | Yes |
619 | 2122 | 2122.0 | 68.45 | 68.5 | RELION: implementation of a Bayesian approach to cryo-EM structure determination. | Sjors H W Scheres | J Struct Biol | 2012 | 23000701 | Yes |
620 | 2121 | 2121.0 | 59.19 | 59.2 | Structure and function of telomeres. | E H Blackburn | Nature | 1991 | 1708110 | No |
621 | 2118 | 2118.0 | 0.0 | 0.0 | A protein binding assay for adenosine 3':5'-cyclic monophosphate. | A G Gilman | Proc Natl Acad Sci U S A | 1970 | 4318781 | Yes |
622 | 4232 | 2116.0 | 116.72 | 58.4 | Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. | D Hanahan, J Folkman | Cell | 1996 | 8756718 | No |
623 | 4228 | 2114.0 | 263.02 | 131.5 | Revised methods for the Salmonella mutagenicity test. | D M Maron, B N Ames | Mutat Res | 1983 | 6341825 | Yes |
624 | 6342 | 2114.0 | 127.31 | 42.4 | Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. | Ron Edgar, Michael Domrachev, Alex E Lash | Nucleic Acids Res | 2002 | 11752295 | Yes |
625 | 2113 | 2113.0 | 47.59 | 47.6 | Getting started with yeast. | F Sherman | Methods Enzymol | 1991 | 2005794 | Yes |
626 | 6334 | 2111.3 | 193.68 | 64.6 | Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. | C M Gorman, L F Moffat, B H Howard | Mol Cell Biol | 1982 | 6960240 | Yes |
627 | 16887 | 2110.9 | 411.88 | 51.5 | The Protein Data Bank. | H M Berman, J Westbrook, Z Feng, G Gilliland, T N Bhat, H Weissig, I N Shindyalov, P E Bourne | Nucleic Acids Res | 2000 | 10592235 | Yes |
628 | 2108 | 2108.0 | 74.9 | 74.9 | Implications of normal brain development for the pathogenesis of schizophrenia. | D R Weinberger | Arch Gen Psychiatry | 1987 | 3606332 | Yes |
629 | 2101 | 2101.0 | 0.0 | 0.0 | Intracellular aspects of the process of protein synthesis. | G Palade | Science | 1975 | 1096303 | No |
630 | 4181 | 2090.5 | 0.0 | 0.0 | The fluid mosaic model of the structure of cell membranes. | S J Singer, G L Nicolson | Science | 1972 | 4333397 | Yes |
631 | 6263 | 2087.7 | 272.55 | 90.9 | Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. | Allison Tong, Peter Sainsbury, Jonathan Craig | Int J Qual Health Care | 2007 | 17872937 | Yes |
632 | 2083 | 2083.0 | 54.98 | 55.0 | Vascular endothelial growth factor: basic science and clinical progress. | Napoleone Ferrara | Endocr Rev | 2004 | 15294883 | No |
633 | 4159 | 2079.5 | 156.02 | 78.0 | Complex network measures of brain connectivity: uses and interpretations. | Mikail Rubinov, Olaf Sporns | Neuroimage | 2010 | 19819337 | Yes |
634 | 2078 | 2078.0 | 0.0 | 0.0 | Colorimetric assay of catalase. | A K Sinha | Anal Biochem | 1972 | 4556490 | Yes |
635 | 2075 | 2075.0 | 0.0 | 0.0 | The genetical structure of populations. | S WRIGHT | Ann Eugen | 1951 | 24540312 | Yes |
636 | 2074 | 2074.0 | 96.81 | 96.8 | Measures of reliability in sports medicine and science. | W G Hopkins | Sports Med | 2000 | 10907753 | Yes |
637 | 2074 | 2074.0 | 54.23 | 54.2 | MapChart: software for the graphical presentation of linkage maps and QTLs. | R E Voorrips | J Hered | 2002 | 12011185 | Yes |
638 | 2070 | 2070.0 | 96.48 | 96.5 | You want to measure coping but your protocol's too long: consider the brief COPE. | C S Carver | Int J Behav Med | 1997 | 16250744 | Yes |
639 | 2067 | 2067.0 | 80.38 | 80.4 | Inositol trisphosphate and diacylglycerol: two interacting second messengers. | M J Berridge | Annu Rev Biochem | 1987 | 3304132 | No |
640 | 2063 | 2063.0 | 65.79 | 65.8 | The nerve growth factor 35 years later. | R Levi-Montalcini | Science | 1987 | 3306916 | No |
641 | 2058 | 2058.0 | 39.63 | 39.6 | Java Treeview--extensible visualization of microarray data. | Alok J Saldanha | Bioinformatics | 2004 | 15180930 | Yes |
642 | 2058 | 2058.0 | 50.61 | 50.6 | Angiogenesis in life, disease and medicine. | Peter Carmeliet | Nature | 2005 | 16355210 | No |
643 | 6163 | 2054.3 | 0.0 | 0.0 | Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane. | G Fairbanks, T L Steck, D F Wallach | Biochemistry | 1971 | 4326772 | Yes |
644 | 2054 | 2054.0 | 55.54 | 55.5 | Causes and consequences of microRNA dysregulation in cancer. | Carlo M Croce | Nat Rev Genet | 2009 | 19763153 | No |
645 | 4107 | 2053.5 | 88.38 | 44.2 | Untangling the ErbB signalling network. | Y Yarden, M X Sliwkowski | Nat Rev Mol Cell Biol | 2001 | 11252954 | No |
646 | 4096 | 2048.0 | 0.0 | 0.0 | Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. | J Sedlak, R H Lindsay | Anal Biochem | 1968 | 4973948 | Yes |
647 | 2047 | 2047.0 | 84.27 | 84.3 | What is value in health care? | Michael E Porter | N Engl J Med | 2010 | 21142528 | Yes |
648 | 4089 | 2044.5 | 109.77 | 54.9 | Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. | Weizhong Li, Adam Godzik | Bioinformatics | 2006 | 16731699 | Yes |
649 | 2042 | 2042.0 | 0.0 | 0.0 | Satellite cell of skeletal muscle fibers. | A MAURO | J Biophys Biochem Cytol | 1961 | 13768451 | Yes |
650 | 2040 | 2040.0 | 56.96 | 57.0 | Cancer nanotechnology: opportunities and challenges. | Mauro Ferrari | Nat Rev Cancer | 2005 | 15738981 | No |
651 | 4078 | 2039.0 | 207.01 | 103.5 | The qualitative content analysis process. | Satu Elo, Helvi Kyngäs | J Adv Nurs | 2008 | 18352969 | Yes |
652 | 2038 | 2038.0 | 71.58 | 71.6 | Accelerated Profile HMM Searches. | Sean R Eddy | PLoS Comput Biol | 2011 | 22039361 | Yes |
653 | 2036 | 2036.0 | 49.02 | 49.0 | Molecular physiology of P2X receptors. | R Alan North | Physiol Rev | 2002 | 12270951 | No |
654 | 2036 | 2036.0 | 52.14 | 52.1 | Calcium signaling. | David E Clapham | Cell | 2007 | 18083096 | No |
655 | 4070 | 2035.0 | 85.98 | 43.0 | CDK inhibitors: positive and negative regulators of G1-phase progression. | C J Sherr, J M Roberts | Genes Dev | 1999 | 10385618 | No |
656 | 2033 | 2033.0 | 43.58 | 43.6 | Tumour-educated macrophages promote tumour progression and metastasis. | Jeffrey W Pollard | Nat Rev Cancer | 2004 | 14708027 | No |
657 | 6081 | 2027.0 | 0.0 | 0.0 | Immunochemical quantitation of antigens by single radial immunodiffusion. | G Mancini, A O Carbonara, J F Heremans | Immunochemistry | 1965 | 4956917 | Yes |
658 | 4050 | 2025.0 | 158.35 | 79.2 | The neural basis of drug craving: an incentive-sensitization theory of addiction. | T E Robinson, K C Berridge | Brain Res Brain Res Rev | 1993 | 8401595 | No |
659 | 2025 | 2025.0 | 47.06 | 47.1 | Evolving concepts of rheumatoid arthritis. | Gary S Firestein | Nature | 2003 | 12748655 | No |
660 | 2023 | 2023.0 | 106.51 | 106.5 | Qualitative research. Introducing focus groups. | J Kitzinger | BMJ | 1995 | 7633241 | Yes |
661 | 4042 | 2021.0 | 0.0 | 0.0 | Electrochemical photolysis of water at a semiconductor electrode. | A Fujishima, K Honda | Nature | 1972 | 12635268 | Yes |
662 | 2015 | 2015.0 | 0.0 | 0.0 | A study of fixation for electron microscopy. | G E PALADE | J Exp Med | 1952 | 14927794 | Yes |
663 | 4028 | 2014.0 | 85.2 | 42.6 | Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. | D Bonnet, J E Dick | Nat Med | 1997 | 9212098 | Yes |
664 | 4015 | 2007.5 | 160.56 | 80.3 | Glutathione. | A Meister, M E Anderson | Annu Rev Biochem | 1983 | 6137189 | No |
665 | 12042 | 2007.0 | 307.61 | 51.3 | Phaser crystallographic software. | Airlie J McCoy, Ralf W Grosse-Kunstleve, Paul D Adams, Martyn D Winn, Laurent C Storoni, Randy J Read | J Appl Crystallogr | 2007 | 19461840 | Yes |
666 | 4012 | 2006.0 | 0.0 | 0.0 | The serial cultivation of human diploid cell strains. | L HAYFLICK, P S MOORHEAD | Exp Cell Res | 1961 | 13905658 | Yes |
667 | 2004 | 2004.0 | 0.0 | 0.0 | Transduction of linked genetic characters of the host by bacteriophage P1. | E S LENNOX | Virology | 1955 | 13267987 | Yes |
668 | 4007 | 2003.5 | 88.32 | 44.2 | Lipid rafts and signal transduction. | K Simons, D Toomre | Nat Rev Mol Cell Biol | 2000 | 11413487 | No |
669 | 2002 | 2002.0 | 67.56 | 67.6 | adegenet: a R package for the multivariate analysis of genetic markers. | Thibaut Jombart | Bioinformatics | 2008 | 18397895 | Yes |
670 | 1996 | 1996.0 | 71.65 | 71.7 | What are the functional consequences of neurocognitive deficits in schizophrenia? | M F Green | Am J Psychiatry | 1996 | 8610818 | No |
671 | 1996 | 1996.0 | 89.58 | 89.6 | The Danish Civil Registration System. | Carsten Bøcker Pedersen | Scand J Public Health | 2011 | 21775345 | Yes |
672 | 5974 | 1991.3 | 422.22 | 140.7 | Methods for dietary fiber, neutral detergent fiber, and nonstarch polysaccharides in relation to animal nutrition. | P J Van Soest, J B Robertson, B A Lewis | J Dairy Sci | 1991 | 1660498 | No |
673 | 3982 | 1991.0 | 144.83 | 72.4 | Rapid isolation of high molecular weight plant DNA. | M G Murray, W F Thompson | Nucleic Acids Res | 1980 | 7433111 | Yes |
674 | 1990 | 1990.0 | 59.86 | 59.9 | The magical number 4 in short-term memory: a reconsideration of mental storage capacity. | N Cowan | Behav Brain Sci | 2001 | 11515286 | Yes |
675 | 5966 | 1988.7 | 0.0 | 0.0 | THE PREPARATION OF I-131-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY. | F C GREENWOOD, W M HUNTER, J S GLOVER | Biochem J | 1963 | 14097352 | Yes |
676 | 3974 | 1987.0 | 119.37 | 59.7 | Management of hepatocellular carcinoma. | Jordi Bruix, Morris Sherman | Hepatology | 2005 | 16250051 | No |
677 | 1985 | 1985.0 | 75.48 | 75.5 | SF-36 health survey update. | J E Ware | Spine (Phila Pa 1976) | 2000 | 11124729 | No |
678 | 1984 | 1984.0 | 84.5 | 84.5 | A computational approach to edge detection. | J Canny | IEEE Trans Pattern Anal Mach Intell | 1986 | 21869365 | Yes |
679 | 1983 | 1983.0 | 44.71 | 44.7 | Telomere measurement by quantitative PCR. | Richard M Cawthon | Nucleic Acids Res | 2002 | 12000852 | Yes |
680 | 1981 | 1981.0 | 81.44 | 81.4 | Matrix metalloproteinases and their inhibitors in connective tissue remodeling. | J F Woessner | FASEB J | 1991 | 1850705 | No |
681 | 3958 | 1979.0 | 83.74 | 41.9 | The phosphatidylinositol 3-Kinase AKT pathway in human cancer. | Igor Vivanco, Charles L Sawyers | Nat Rev Cancer | 2002 | 12094235 | No |
682 | 1978 | 1978.0 | 57.4 | 57.4 | Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface. | G P Smith | Science | 1985 | 4001944 | Yes |
683 | 3955 | 1977.5 | 148.83 | 74.4 | Inositol trisphosphate, a novel second messenger in cellular signal transduction. | M J Berridge, R F Irvine | Nature | 1984 | 6095092 | No |
684 | 1977 | 1977.0 | 0.0 | 0.0 | A rapid radiochemical method for the determination of choline acetyltransferase. | F Fonnum | J Neurochem | 1975 | 1113118 | Yes |
685 | 1975 | 1975.0 | 48.13 | 48.1 | A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. | Douglas C Wallace | Annu Rev Genet | 2005 | 16285865 | No |
686 | 3945 | 1972.5 | 98.26 | 49.1 | Signal integration in the endoplasmic reticulum unfolded protein response. | David Ron, Peter Walter | Nat Rev Mol Cell Biol | 2007 | 17565364 | No |
687 | 1970 | 1970.0 | 65.94 | 65.9 | Two-sided confidence intervals for the single proportion: comparison of seven methods. | R G Newcombe | Stat Med | 1998 | 9595616 | Yes |
688 | 1967 | 1967.0 | 0.0 | 0.0 | The gel-filtration behaviour of proteins related to their molecular weights over a wide range. | P Andrews | Biochem J | 1965 | 5862401 | Yes |
689 | 7843 | 1960.8 | 270.72 | 67.7 | Naive Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy. | Qiong Wang, George M Garrity, James M Tiedje, James R Cole | Appl Environ Microbiol | 2007 | 17586664 | Yes |
690 | 1958 | 1958.0 | 58.77 | 58.8 | Dietary pattern analysis: a new direction in nutritional epidemiology. | Frank B Hu | Curr Opin Lipidol | 2002 | 11790957 | No |
691 | 5868 | 1956.0 | 0.0 | 0.0 | The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. | R J HAVEL, H A EDER, J H BRAGDON | J Clin Invest | 1955 | 13252080 | Yes |
692 | 1956 | 1956.0 | 77.23 | 77.2 | Ethical authorship and publishing. | Andrew J S Coats | Int J Cardiol | 2009 | 19046787 | No |
693 | 1950 | 1950.0 | 64.47 | 64.5 | The anatomy and taxonomy of protein structure. | J S Richardson | Adv Protein Chem | 1981 | 7020376 | No |
694 | 3896 | 1948.0 | 119.3 | 59.6 | Pattern recognition receptors and inflammation. | Osamu Takeuchi, Shizuo Akira | Cell | 2010 | 20303872 | No |
695 | 1946 | 1946.0 | 0.0 | 0.0 | Elastic properties of lipid bilayers: theory and possible experiments. | W Helfrich | Z Naturforsch C | 1973 | 4273690 | Yes |
696 | 3886 | 1943.0 | 158.2 | 79.1 | The L-arginine-nitric oxide pathway. | S Moncada, A Higgs | N Engl J Med | 1993 | 7504210 | No |
697 | 1943 | 1943.0 | 52.46 | 52.5 | A mechanism for cognitive dynamics: neuronal communication through neuronal coherence. | Pascal Fries | Trends Cogn Sci | 2005 | 16150631 | No |
698 | 1941 | 1941.0 | 54.11 | 54.1 | Molecular basis of bacterial outer membrane permeability revisited. | Hiroshi Nikaido | Microbiol Mol Biol Rev | 2003 | 14665678 | No |
699 | 1940 | 1940.0 | 41.81 | 41.8 | The molecular biology of memory storage: a dialogue between genes and synapses. | E R Kandel | Science | 2001 | 11691980 | No |
700 | 3878 | 1939.0 | 0.0 | 0.0 | A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. | S REITMAN, S FRANKEL | Am J Clin Pathol | 1957 | 13458125 | Yes |
701 | 3869 | 1934.5 | 82.33 | 41.2 | Mechanisms of TGF-beta signaling from cell membrane to the nucleus. | Yigong Shi, Joan Massagué | Cell | 2003 | 12809600 | No |
702 | 1932 | 1932.0 | 56.47 | 56.5 | Immunological and inflammatory functions of the interleukin-1 family. | Charles A Dinarello | Annu Rev Immunol | 2009 | 19302047 | No |
703 | 1931 | 1931.0 | 77.61 | 77.6 | Working memory. | A Baddeley | Science | 1992 | 1736359 | No |
704 | 1929 | 1929.0 | 53.21 | 53.2 | Ischemic cell death in brain neurons. | P Lipton | Physiol Rev | 1999 | 10508238 | No |
705 | 1929 | 1929.0 | 0.0 | 0.0 | Quantitative estimation of sialic acids. II. A colorimetric resorcinol-hydrochloric acid method. | L SVENNERHOLM | Biochim Biophys Acta | 1957 | 13436486 | Yes |
706 | 1928 | 1928.0 | 45.57 | 45.6 | NOX enzymes and the biology of reactive oxygen. | J David Lambeth | Nat Rev Immunol | 2004 | 15039755 | No |
707 | 3846 | 1923.0 | 0.0 | 0.0 | Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. | L A Greene, A S Tischler | Proc Natl Acad Sci U S A | 1976 | 1065897 | Yes |
708 | 3843 | 1921.5 | 0.0 | 0.0 | A general method applicable to the search for similarities in the amino acid sequence of two proteins. | S B Needleman, C D Wunsch | J Mol Biol | 1970 | 5420325 | Yes |
709 | 5763 | 1921.0 | 164.8 | 54.9 | RNA-Seq: a revolutionary tool for transcriptomics. | Zhong Wang, Mark Gerstein, Michael Snyder | Nat Rev Genet | 2009 | 19015660 | No |
710 | 3839 | 1919.5 | 87.62 | 43.8 | A novel genetic system to detect protein-protein interactions. | S Fields, O Song | Nature | 1989 | 2547163 | Yes |
711 | 3839 | 1919.5 | 90.33 | 45.2 | New functions for the matrix metalloproteinases in cancer progression. | Mikala Egeblad, Zena Werb | Nat Rev Cancer | 2002 | 11990853 | No |
712 | 1918 | 1918.0 | 62.7 | 62.7 | Physiology and neurobiology of stress and adaptation: central role of the brain. | Bruce S McEwen | Physiol Rev | 2007 | 17615391 | No |
713 | 3834 | 1917.0 | 115.95 | 58.0 | Calculation of protein extinction coefficients from amino acid sequence data. | S C Gill, P H von Hippel | Anal Biochem | 1989 | 2610349 | Yes |
714 | 1916 | 1916.0 | 66.93 | 66.9 | Scaffolds in tissue engineering bone and cartilage. | D W Hutmacher | Biomaterials | 2000 | 11071603 | Yes |
715 | 3831 | 1915.5 | 107.66 | 53.8 | Reactive oxygen species: metabolism, oxidative stress, and signal transduction. | Klaus Apel, Heribert Hirt | Annu Rev Plant Biol | 2004 | 15377225 | No |
716 | 1914 | 1914.0 | 37.9 | 37.9 | Targeting RAS signalling pathways in cancer therapy. | Julian Downward | Nat Rev Cancer | 2003 | 12509763 | No |
717 | 3827 | 1913.5 | 180.0 | 90.0 | A feature-integration theory of attention. | A M Treisman, G Gelade | Cogn Psychol | 1980 | 7351125 | Yes |
718 | 1913 | 1913.0 | 49.05 | 49.0 | Modularity and community structure in networks. | M E J Newman | Proc Natl Acad Sci U S A | 2006 | 16723398 | Yes |
719 | 5734 | 1911.3 | 143.88 | 48.0 | The biology of VEGF and its receptors. | Napoleone Ferrara, Hans-Peter Gerber, Jennifer LeCouter | Nat Med | 2003 | 12778165 | No |
720 | 3818 | 1909.0 | 95.55 | 47.8 | Death receptors: signaling and modulation. | A Ashkenazi, V M Dixit | Science | 1998 | 9721089 | No |
721 | 1906 | 1906.0 | 47.84 | 47.8 | G1 phase progression: cycling on cue. | C J Sherr | Cell | 1994 | 7954821 | No |
722 | 1902 | 1902.0 | 46.95 | 47.0 | Mitochondrial diseases in man and mouse. | D C Wallace | Science | 1999 | 10066162 | No |
723 | 5701 | 1900.3 | 191.9 | 64.0 | Bacterial biofilms: a common cause of persistent infections. | J W Costerton, P S Stewart, E P Greenberg | Science | 1999 | 10334980 | No |
724 | 3796 | 1898.0 | 159.57 | 79.8 | The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions. | S H Downs, N Black | J Epidemiol Community Health | 1998 | 9764259 | Yes |
725 | 3796 | 1898.0 | 0.0 | 0.0 | A modified uronic acid carbazole reaction. | T BITTER, H M MUIR | Anal Biochem | 1962 | 13971270 | Yes |
726 | 3781 | 1890.5 | 106.33 | 53.2 | A global optimisation method for robust affine registration of brain images. | M Jenkinson, S Smith | Med Image Anal | 2001 | 11516708 | Yes |
727 | 1889 | 1889.0 | 57.83 | 57.8 | Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. | E C Butcher | Cell | 1991 | 1760836 | No |
728 | 1887 | 1887.0 | 44.9 | 44.9 | Universal control mechanism regulating onset of M-phase. | P Nurse | Nature | 1990 | 2138713 | No |
729 | 3771 | 1885.5 | 93.21 | 46.6 | AKT/PKB signaling: navigating downstream. | Brendan D Manning, Lewis C Cantley | Cell | 2007 | 17604717 | No |
730 | 1884 | 1884.0 | 62.72 | 62.7 | Dominant forces in protein folding. | K A Dill | Biochemistry | 1990 | 2207096 | No |
731 | 1883 | 1883.0 | 0.0 | 0.0 | On estimating the relation between blood group and disease. | B WOOLF | Ann Hum Genet | 1955 | 14388528 | Yes |
732 | 3755 | 1877.5 | 125.16 | 62.6 | Neural mechanisms of selective visual attention. | R Desimone, J Duncan | Annu Rev Neurosci | 1995 | 7605061 | No |
733 | 7507 | 1876.8 | 236.67 | 59.2 | GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation. | Berk Hess, Carsten Kutzner, David van der Spoel, Erik Lindahl | J Chem Theory Comput | 2008 | 26620784 | Yes |
734 | 1873 | 1873.0 | 68.07 | 68.1 | Biodiesel from microalgae. | Yusuf Chisti | Biotechnol Adv | 2007 | 17350212 | No |
735 | 3745 | 1872.5 | 0.0 | 0.0 | The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. | H P Misra, I Fridovich | J Biol Chem | 1972 | 4623845 | Yes |
736 | 1872 | 1872.0 | 96.09 | 96.1 | Effective physician-patient communication and health outcomes: a review. | M A Stewart | CMAJ | 1995 | 7728691 | Yes |
737 | 3744 | 1872.0 | 151.59 | 75.8 | FLASH: fast length adjustment of short reads to improve genome assemblies. | Tanja Magoč, Steven L Salzberg | Bioinformatics | 2011 | 21903629 | Yes |
738 | 1868 | 1868.0 | 69.74 | 69.7 | A two process model of sleep regulation. | A A Borbély | Hum Neurobiol | 1982 | 7185792 | Yes |
739 | 3735 | 1867.5 | 126.63 | 63.3 | Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. | C J Murray, A D Lopez | Lancet | 1997 | 9167458 | Yes |
740 | 1864 | 1864.0 | 0.0 | 0.0 | A RAPID PERMETHYLATION OF GLYCOLIPID, AND POLYSACCHARIDE CATALYZED BY METHYLSULFINYL CARBANION IN DIMETHYL SULFOXIDE. | S HAKOMORI | J Biochem | 1964 | 14135466 | Yes |
741 | 1861 | 1861.0 | 46.62 | 46.6 | Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. | T Hunter | Cell | 1995 | 7834742 | No |
742 | 5576 | 1858.7 | 295.32 | 98.4 | Detection of postnatal depression. Development of the 10-item Edinburgh Postnatal Depression Scale. | J L Cox, J M Holden, R Sagovsky | Br J Psychiatry | 1987 | 3651732 | Yes |
743 | 1856 | 1856.0 | 52.93 | 52.9 | Biology of natural killer cells. | G Trinchieri | Adv Immunol | 1989 | 2683611 | No |
744 | 3707 | 1853.5 | 115.85 | 57.9 | Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. | Michael D Fox, Marcus E Raichle | Nat Rev Neurosci | 2007 | 17704812 | No |
745 | 3705 | 1852.5 | 102.91 | 51.5 | Nonparametric permutation tests for functional neuroimaging: a primer with examples. | Thomas E Nichols, Andrew P Holmes | Hum Brain Mapp | 2002 | 11747097 | Yes |
746 | 3701 | 1850.5 | 173.59 | 86.8 | Self-rated health and mortality: a review of twenty-seven community studies. | E L Idler, Y Benyamini | J Health Soc Behav | 1997 | 9097506 | No |
747 | 1844 | 1844.0 | 63.57 | 63.6 | Japanese Classification of Gastric Carcinoma - 2nd English Edition - | Japanese Gastric Cancer Association | Gastric Cancer | 1998 | 11957040 | Yes |
748 | 1843 | 1843.0 | 38.15 | 38.1 | NK cell recognition. | Lewis L Lanier | Annu Rev Immunol | 2005 | 15771571 | No |
749 | 3685 | 1842.5 | 0.0 | 0.0 | Screening lambdagt recombinant clones by hybridization to single plaques in situ. | W D Benton, R W Davis | Science | 1977 | 322279 | Yes |
750 | 7360 | 1840.0 | 297.47 | 74.4 | A consistent and accurate ab initio parametrization of density functional dispersion correction (DFT-D) for the 94 elements H-Pu. | Stefan Grimme, Jens Antony, Stephan Ehrlich, Helge Krieg | J Chem Phys | 2010 | 20423165 | Yes |
751 | 3675 | 1837.5 | 106.12 | 53.1 | The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. | Karen Bedard, Karl-Heinz Krause | Physiol Rev | 2007 | 17237347 | No |
752 | 1836 | 1836.0 | 0.0 | 0.0 | A simple technique for demonstrating centromeric heterochromatin. | A T Sumner | Exp Cell Res | 1972 | 4117921 | Yes |
753 | 1836 | 1836.0 | 0.0 | 0.0 | The information capacity of the human motor system in controlling the amplitude of movement. | P M FITTS | J Exp Psychol | 1954 | 13174710 | Yes |
754 | 1835 | 1835.0 | 46.68 | 46.7 | Chemokines and leukocyte traffic. | M Baggiolini | Nature | 1998 | 9560152 | No |
755 | 1834 | 1834.0 | 0.0 | 0.0 | The biology of oxygen radicals. | I Fridovich | Science | 1978 | 210504 | Yes |
756 | 1834 | 1834.0 | 78.25 | 78.2 | Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. | B Samuelsson | Science | 1983 | 6301011 | Yes |
757 | 1834 | 1834.0 | 36.69 | 36.7 | Histone acetylation in chromatin structure and transcription. | M Grunstein | Nature | 1997 | 9311776 | No |
758 | 1834 | 1834.0 | 41.27 | 41.3 | Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. | Shimon Sakaguchi | Nat Immunol | 2005 | 15785760 | No |
759 | 1826 | 1826.0 | 46.09 | 46.1 | Rab GTPases as coordinators of vesicle traffic. | Harald Stenmark | Nat Rev Mol Cell Biol | 2009 | 19603039 | No |
760 | 1825 | 1825.0 | 72.45 | 72.5 | Reactive oxygen species and the central nervous system. | B Halliwell | J Neurochem | 1992 | 1402908 | No |
761 | 1823 | 1823.0 | 45.11 | 45.1 | Complement. First of two parts. | M J Walport | N Engl J Med | 2001 | 11287977 | No |
762 | 3644 | 1822.0 | 98.19 | 49.1 | Protein misfolding, functional amyloid, and human disease. | Fabrizio Chiti, Christopher M Dobson | Annu Rev Biochem | 2006 | 16756495 | No |
763 | 1820 | 1820.0 | 62.59 | 62.6 | Human gastric carcinogenesis: a multistep and multifactorial process--First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. | P Correa | Cancer Res | 1992 | 1458460 | No |
764 | 3639 | 1819.5 | 98.6 | 49.3 | Myeloid-derived suppressor cells as regulators of the immune system. | Dmitry I Gabrilovich, Srinivas Nagaraj | Nat Rev Immunol | 2009 | 19197294 | No |
765 | 1817 | 1817.0 | 85.66 | 85.7 | Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminals. | H W Steinbusch | Neuroscience | 1981 | 7017455 | Yes |
766 | 1816 | 1816.0 | 56.14 | 56.1 | A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data. | Heng Li | Bioinformatics | 2011 | 21903627 | Yes |
767 | 1814 | 1814.0 | 49.16 | 49.2 | SV40-transformed simian cells support the replication of early SV40 mutants. | Y Gluzman | Cell | 1981 | 6260373 | Yes |
768 | 1814 | 1814.0 | 0.0 | 0.0 | Isolation by Distance. | S Wright | Genetics | 1943 | 17247074 | Yes |
769 | 3627 | 1813.5 | 152.77 | 76.4 | Random-effects models for longitudinal data. | N M Laird, J H Ware | Biometrics | 1982 | 7168798 | Yes |
770 | 1813 | 1813.0 | 42.35 | 42.4 | Cisplatin: mode of cytotoxic action and molecular basis of resistance. | Zahid H Siddik | Oncogene | 2003 | 14576837 | No |
771 | 1811 | 1811.0 | 62.12 | 62.1 | Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide to nitrocellulose. | J Kyhse-Andersen | J Biochem Biophys Methods | 1984 | 6530509 | Yes |
772 | 1811 | 1811.0 | 48.63 | 48.6 | Contrasting mechanisms of defense against biotrophic and necrotrophic pathogens. | Jane Glazebrook | Annu Rev Phytopathol | 2005 | 16078883 | No |
773 | 1810 | 1810.0 | 107.62 | 107.6 | Interrater reliability: the kappa statistic. | Mary L McHugh | Biochem Med (Zagreb) | 2012 | 23092060 | Yes |
774 | 5416 | 1805.3 | 151.8 | 50.6 | ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. | Kai Wang, Mingyao Li, Hakon Hakonarson | Nucleic Acids Res | 2010 | 20601685 | Yes |
775 | 3606 | 1803.0 | 112.73 | 56.4 | Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. | C W Elston, I O Ellis | Histopathology | 1991 | 1757079 | Yes |
776 | 3603 | 1801.5 | 0.0 | 0.0 | Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid. | J D WATSON, F H CRICK | Nature | 1953 | 13054692 | Yes |
777 | 1801 | 1801.0 | 57.5 | 57.5 | Efficient methods to compute genomic predictions. | P M VanRaden | J Dairy Sci | 2008 | 18946147 | Yes |
778 | 1798 | 1798.0 | 57.52 | 57.5 | The episodic buffer: a new component of working memory? | Baddeley | Trends Cogn Sci | 2000 | 11058819 | Yes |
779 | 1797 | 1797.0 | 36.57 | 36.6 | Shelterin: the protein complex that shapes and safeguards human telomeres. | Titia de Lange | Genes Dev | 2005 | 16166375 | No |
780 | 1796 | 1796.0 | 56.14 | 56.1 | Pancreatic cancer. | Manuel Hidalgo | N Engl J Med | 2010 | 20427809 | No |
781 | 3589 | 1794.5 | 88.97 | 44.5 | Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. | F Sallusto, A Lanzavecchia | J Exp Med | 1994 | 8145033 | Yes |
782 | 1794 | 1794.0 | 54.64 | 54.6 | A model for receptor-regulated calcium entry. | J W Putney | Cell Calcium | 1986 | 2420465 | No |
783 | 3587 | 1793.5 | 85.47 | 42.7 | Mass spectrometry-based proteomics. | Ruedi Aebersold, Matthias Mann | Nature | 2003 | 12634793 | No |
784 | 1793 | 1793.0 | 60.29 | 60.3 | Parkinson's disease: clinical features and diagnosis. | J Jankovic | J Neurol Neurosurg Psychiatry | 2008 | 18344392 | No |
785 | 1792 | 1792.0 | 70.85 | 70.8 | DNA methylation age of human tissues and cell types. | Steve Horvath | Genome Biol | 2013 | 24138928 | Yes |
786 | 3583 | 1791.5 | 105.73 | 52.9 | Acute-phase proteins and other systemic responses to inflammation. | C Gabay, I Kushner | N Engl J Med | 1999 | 9971870 | No |
787 | 3582 | 1791.0 | 101.28 | 50.6 | Signal transduction by receptors with tyrosine kinase activity. | A Ullrich, J Schlessinger | Cell | 1990 | 2158859 | No |
788 | 1790 | 1790.0 | 64.02 | 64.0 | Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication. | H G Gratzner | Science | 1982 | 7123245 | Yes |
789 | 3577 | 1788.5 | 93.76 | 46.9 | The Bcl-2 protein family: arbiters of cell survival. | J M Adams, S Cory | Science | 1998 | 9735050 | No |
790 | 1788 | 1788.0 | 74.29 | 74.3 | Role of oxidative stress in development of complications in diabetes. | J W Baynes | Diabetes | 1991 | 2010041 | No |
791 | 3575 | 1787.5 | 142.49 | 71.2 | Accurate and simple analytic representation of the electron-gas correlation energy. | Perdew, Wang | Phys Rev B Condens Matter | 1992 | 10001404 | Yes |
792 | 1787 | 1787.0 | 45.7 | 45.7 | The regulation of AP-1 activity by mitogen-activated protein kinases. | M Karin | J Biol Chem | 1995 | 7622446 | No |
793 | 1783 | 1783.0 | 49.05 | 49.0 | Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences. | Edward V Loftus | Gastroenterology | 2004 | 15168363 | Yes |
794 | 3565 | 1782.5 | 177.81 | 88.9 | A simple, rapid, and sensitive DNA assay procedure. | C Labarca, K Paigen | Anal Biochem | 1980 | 6158890 | Yes |
795 | 5345 | 1781.7 | 110.28 | 36.8 | Control of regulatory T cell development by the transcription factor Foxp3. | Shohei Hori, Takashi Nomura, Shimon Sakaguchi | Science | 2003 | 12522256 | Yes |
796 | 1781 | 1781.0 | 54.93 | 54.9 | Descending control of pain. | Mark J Millan | Prog Neurobiol | 2002 | 12034378 | No |
797 | 3559 | 1779.5 | 103.13 | 51.6 | UniFrac: a new phylogenetic method for comparing microbial communities. | Catherine Lozupone, Rob Knight | Appl Environ Microbiol | 2005 | 16332807 | Yes |
798 | 1778 | 1778.0 | 80.27 | 80.3 | Glutamate, nitric oxide and cell-cell signalling in the nervous system. | J Garthwaite | Trends Neurosci | 1991 | 1708538 | No |
799 | 3555 | 1777.5 | 0.0 | 0.0 | Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. | T V Bliss, T Lomo | J Physiol | 1973 | 4727084 | Yes |
800 | 1776 | 1776.0 | 58.36 | 58.4 | A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. | P Chomczynski | Biotechniques | 1993 | 7692896 | Yes |
801 | 1776 | 1776.0 | 59.55 | 59.5 | Stress, adaptation, and disease. Allostasis and allostatic load. | B S McEwen | Ann N Y Acad Sci | 1998 | 9629234 | No |
802 | 10656 | 1776.0 | 408.47 | 68.1 | Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. | Jacques Ferlay, Hai-Rim Shin, Freddie Bray, David Forman, Colin Mathers, Donald Maxwell Parkin | Int J Cancer | 2010 | 21351269 | Yes |
803 | 3539 | 1769.5 | 108.04 | 54.0 | Application of phylogenetic networks in evolutionary studies. | Daniel H Huson, David Bryant | Mol Biol Evol | 2006 | 16221896 | Yes |
804 | 5298 | 1766.0 | 152.48 | 50.8 | Cortical surface-based analysis. I. Segmentation and surface reconstruction. | A M Dale, B Fischl, M I Sereno | Neuroimage | 1999 | 9931268 | Yes |
805 | 3531 | 1765.5 | 0.0 | 0.0 | Quantitative film detection of 3H and 14C in polyacrylamide gels by fluorography. | R A Laskey, A D Mills | Eur J Biochem | 1975 | 1175627 | Yes |
806 | 3531 | 1765.5 | 104.3 | 52.1 | Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. | E Lander, L Kruglyak | Nat Genet | 1995 | 7581446 | Yes |
807 | 1765 | 1765.0 | 42.43 | 42.4 | Nitric oxide and the immune response. | C Bogdan | Nat Immunol | 2001 | 11577346 | No |
808 | 1765 | 1765.0 | 112.47 | 112.5 | Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs. | Daniël Lakens | Front Psychol | 2013 | 24324449 | No |
809 | 3529 | 1764.5 | 131.92 | 66.0 | Missing data: our view of the state of the art. | Joseph L Schafer, John W Graham | Psychol Methods | 2002 | 12090408 | Yes |
810 | 1764 | 1764.0 | 70.77 | 70.8 | Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. | W A Craig | Clin Infect Dis | 1998 | 9455502 | No |
811 | 1764 | 1764.0 | 0.0 | 0.0 | Catheter replacement of the needle in percutaneous arteriography; a new technique. | S I SELDINGER | Acta radiol | 1953 | 13057644 | Yes |
812 | 3526 | 1763.0 | 0.0 | 0.0 | The interpretation of protein structures: estimation of static accessibility. | B Lee, F M Richards | J Mol Biol | 1971 | 5551392 | Yes |
813 | 1763 | 1763.0 | 88.34 | 88.3 | Central sensitization: implications for the diagnosis and treatment of pain. | Clifford J Woolf | Pain | 2011 | 20961685 | No |
814 | 3524 | 1762.0 | 197.81 | 98.9 | Clinical significance: a statistical approach to defining meaningful change in psychotherapy research. | N S Jacobson, P Truax | J Consult Clin Psychol | 1991 | 2002127 | Yes |
815 | 1761 | 1761.0 | 47.89 | 47.9 | Inferring the historical patterns of biological evolution. | M Pagel | Nature | 1999 | 10553904 | Yes |
816 | 1760 | 1760.0 | 48.09 | 48.1 | Specification of cerebral cortical areas. | P Rakic | Science | 1988 | 3291116 | No |
817 | 7029 | 1757.2 | 169.92 | 42.5 | Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. | A Krogh, B Larsson, G von Heijne, E L Sonnhammer | J Mol Biol | 2001 | 11152613 | Yes |
818 | 1757 | 1757.0 | 0.0 | 0.0 | A RATIONALE AND TEST FOR THE NUMBER OF FACTORS IN FACTOR ANALYSIS. | J L HORN | Psychometrika | 1965 | 14306381 | Yes |
819 | 3514 | 1757.0 | 106.29 | 53.1 | Gold nanoparticles: assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology. | Marie-Christine Daniel, Didier Astruc | Chem Rev | 2004 | 14719978 | No |
820 | 1757 | 1757.0 | 61.2 | 61.2 | Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity-score matched samples. | Peter C Austin | Stat Med | 2009 | 19757444 | Yes |
821 | 1756 | 1756.0 | 47.37 | 47.4 | The inflammatory reflex. | Kevin J Tracey | Nature | 2002 | 12490958 | No |
822 | 3506 | 1753.0 | 0.0 | 0.0 | The Social Readjustment Rating Scale. | T H Holmes, R H Rahe | J Psychosom Res | 1967 | 6059863 | Yes |
823 | 1753 | 1753.0 | 71.72 | 71.7 | Spinal and supraspinal factors in human muscle fatigue. | S C Gandevia | Physiol Rev | 2001 | 11581501 | No |
824 | 3506 | 1753.0 | 95.74 | 47.9 | Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. | Hashem B El-Serag, K Lenhard Rudolph | Gastroenterology | 2007 | 17570226 | No |
825 | 1753 | 1753.0 | 63.52 | 63.5 | The unfolded protein response: controlling cell fate decisions under ER stress and beyond. | Claudio Hetz | Nat Rev Mol Cell Biol | 2012 | 22251901 | No |
826 | 1751 | 1751.0 | 0.0 | 0.0 | Muscle structure and theories of contraction. | A F HUXLEY | Prog Biophys Biophys Chem | 1957 | 13485191 | Yes |
827 | 3501 | 1750.5 | 77.77 | 38.9 | Mammalian MAP kinase signalling cascades. | L Chang, M Karin | Nature | 2001 | 11242034 | No |
828 | 3501 | 1750.5 | 73.23 | 36.6 | Network biology: understanding the cell's functional organization. | Albert-László Barabási, Zoltán N Oltvai | Nat Rev Genet | 2004 | 14735121 | No |
829 | 1750 | 1750.0 | 67.95 | 68.0 | The unbiased estimation of number and sizes of arbitrary particles using the disector. | D C Sterio | J Microsc | 1984 | 6737468 | Yes |
830 | 1749 | 1749.0 | 51.93 | 51.9 | Working memory: looking back and looking forward. | Alan Baddeley | Nat Rev Neurosci | 2003 | 14523382 | No |
831 | 1748 | 1748.0 | 54.14 | 54.1 | The heme oxygenase system: a regulator of second messenger gases. | M D Maines | Annu Rev Pharmacol Toxicol | 1997 | 9131263 | No |
832 | 3495 | 1747.5 | 0.0 | 0.0 | A method for determining the sedimentation behavior of enzymes: application to protein mixtures. | R G MARTIN, B N AMES | J Biol Chem | 1961 | 13767412 | Yes |
833 | 1746 | 1746.0 | 71.63 | 71.6 | Epidemiology of viral hepatitis and hepatocellular carcinoma. | Hashem B El-Serag | Gastroenterology | 2012 | 22537432 | No |
834 | 1744 | 1744.0 | 0.0 | 0.0 | Protein purification by affinity chromatography. Derivatizations of agarose and polyacrylamide beads. | P Cuatrecasas | J Biol Chem | 1970 | 5432796 | Yes |
835 | 1744 | 1744.0 | 57.42 | 57.4 | Estimating causal effects from large data sets using propensity scores. | D B Rubin | Ann Intern Med | 1997 | 9382394 | No |
836 | 1743 | 1743.0 | 36.66 | 36.7 | Mechanisms of type-I- and type-II-interferon-mediated signalling. | Leonidas C Platanias | Nat Rev Immunol | 2005 | 15864272 | No |
837 | 1742 | 1742.0 | 48.84 | 48.8 | RGD and other recognition sequences for integrins. | E Ruoslahti | Annu Rev Cell Dev Biol | 1996 | 8970741 | No |
838 | 1738 | 1738.0 | 0.0 | 0.0 | SEDIMENTATION STUDIES OF THE SIZE AND SHAPE OF DNA. | F W STUDIER | J Mol Biol | 1965 | 14290352 | Yes |
839 | 5208 | 1736.0 | 163.36 | 54.5 | Immunity, inflammation, and cancer. | Sergei I Grivennikov, Florian R Greten, Michael Karin | Cell | 2010 | 20303878 | No |
840 | 3469 | 1734.5 | 119.89 | 59.9 | Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. | J S Beckman, W H Koppenol | Am J Physiol | 1996 | 8944624 | No |
841 | 13858 | 1732.2 | 548.68 | 68.6 | The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. | D M Nathan, S Genuth, J Lachin, P Cleary, O Crofford, M Davis, L Rand, C Siebert | N Engl J Med | 1993 | 8366922 | Yes |
842 | 1730 | 1730.0 | 0.0 | 0.0 | The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes. | S BOYDEN | J Exp Med | 1962 | 13872176 | Yes |
843 | 1729 | 1729.0 | 59.89 | 59.9 | Molecular diversity of glutamate receptors and implications for brain function. | S Nakanishi | Science | 1992 | 1329206 | No |
844 | 1729 | 1729.0 | 47.37 | 47.4 | Social controls on cell survival and cell death. | M C Raff | Nature | 1992 | 1557121 | No |
845 | 5187 | 1729.0 | 244.8 | 81.6 | Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA. | G Muyzer, E C de Waal, A G Uitterlinden | Appl Environ Microbiol | 1993 | 7683183 | Yes |
846 | 3456 | 1728.0 | 186.11 | 93.1 | phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data. | Paul J McMurdie, Susan Holmes | PLoS One | 2013 | 23630581 | Yes |
847 | 3454 | 1727.0 | 101.7 | 50.9 | Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. | M Matsuda, R A DeFronzo | Diabetes Care | 1999 | 10480510 | Yes |
848 | 1727 | 1727.0 | 49.62 | 49.6 | T cell exhaustion. | E John Wherry | Nat Immunol | 2011 | 21739672 | No |
849 | 1725 | 1725.0 | 0.0 | 0.0 | Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. | F F Jöbsis | Science | 1977 | 929199 | Yes |
850 | 1723 | 1723.0 | 102.9 | 102.9 | Structural Model Evaluation and Modification: An Interval Estimation Approach. | J H Steiger | Multivariate Behav Res | 1990 | 26794479 | Yes |
851 | 1721 | 1721.0 | 73.15 | 73.2 | Qualitative research: standards, challenges, and guidelines. | K Malterud | Lancet | 2001 | 11513933 | Yes |
852 | 3440 | 1720.0 | 130.4 | 65.2 | A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. | Gary J Bennett, Y-K Xie | Pain | 1988 | 2837713 | Yes |
853 | 3435 | 1717.5 | 115.33 | 57.7 | The number of people with glaucoma worldwide in 2010 and 2020. | H A Quigley, A T Broman | Br J Ophthalmol | 2006 | 16488940 | Yes |
854 | 1717 | 1717.0 | 78.15 | 78.2 | International experiences with the Hospital Anxiety and Depression Scale--a review of validation data and clinical results. | C Herrmann | J Psychosom Res | 1997 | 9055211 | No |
855 | 1717 | 1717.0 | 32.23 | 32.2 | ATM and related protein kinases: safeguarding genome integrity. | Yosef Shiloh | Nat Rev Cancer | 2003 | 12612651 | No |
856 | 1717 | 1717.0 | 0.0 | 0.0 | Studies on lysogenesis. I. The mode of phage liberation by lysogenic Escherichia coli. | G BERTANI | J Bacteriol | 1951 | 14888646 | Yes |
857 | 5149 | 1716.3 | 326.51 | 108.8 | Deep learning. | Yann LeCun, Yoshua Bengio, Geoffrey Hinton | Nature | 2015 | 26017442 | No |
858 | 3424 | 1712.0 | 91.29 | 45.6 | Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. | B A Reynolds, S Weiss | Science | 1992 | 1553558 | Yes |
859 | 10264 | 1710.7 | 331.86 | 55.3 | A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. | A S Levey, J P Bosch, J B Lewis, T Greene, N Rogers, D Roth | Ann Intern Med | 1999 | 10075613 | Yes |
860 | 10244 | 1707.3 | 247.92 | 41.3 | NMRPipe: a multidimensional spectral processing system based on UNIX pipes. | F Delaglio, S Grzesiek, G W Vuister, G Zhu, J Pfeifer, A Bax | J Biomol NMR | 1995 | 8520220 | Yes |
861 | 5121 | 1707.0 | 133.3 | 44.4 | MOLMOL: a program for display and analysis of macromolecular structures. | R Koradi, M Billeter, K Wüthrich | J Mol Graph | 1996 | 8744573 | Yes |
862 | 3414 | 1707.0 | 133.65 | 66.8 | Self-determination theory and the facilitation of intrinsic motivation, social development, and well-being. | R M Ryan, E L Deci | Am Psychol | 2000 | 11392867 | Yes |
863 | 1706 | 1706.0 | 54.86 | 54.9 | Carbonic anhydrases: novel therapeutic applications for inhibitors and activators. | Claudiu T Supuran | Nat Rev Drug Discov | 2008 | 18167490 | No |
864 | 3411 | 1705.5 | 78.76 | 39.4 | Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. | M Gossen, H Bujard | Proc Natl Acad Sci U S A | 1992 | 1319065 | Yes |
865 | 3410 | 1705.0 | 72.17 | 36.1 | The Wnt signaling pathway in development and disease. | Catriona Y Logan, Roel Nusse | Annu Rev Cell Dev Biol | 2004 | 15473860 | No |
866 | 1704 | 1704.0 | 38.51 | 38.5 | Molecular bases for circadian clocks. | J C Dunlap | Cell | 1999 | 9988221 | No |
867 | 5105 | 1701.7 | 0.0 | 0.0 | ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL. | J MONOD, J WYMAN, J P CHANGEUX | J Mol Biol | 1965 | 14343300 | Yes |
868 | 1701 | 1701.0 | 0.0 | 0.0 | Stereochemistry of cooperative effects in haemoglobin. | M F Perutz | Nature | 1970 | 5528785 | Yes |
869 | 1701 | 1701.0 | 43.95 | 44.0 | A decade of molecular biology of retinoic acid receptors. | P Chambon | FASEB J | 1996 | 8801176 | No |
870 | 3402 | 1701.0 | 85.75 | 42.9 | Brown adipose tissue: function and physiological significance. | Barbara Cannon, Jan Nedergaard | Physiol Rev | 2004 | 14715917 | No |
871 | 1700 | 1700.0 | 69.55 | 69.5 | A classification of glycosyl hydrolases based on amino acid sequence similarities. | B Henrissat | Biochem J | 1991 | 1747104 | Yes |
872 | 1698 | 1698.0 | 0.0 | 0.0 | The Michigan alcoholism screening test: the quest for a new diagnostic instrument. | M L Selzer | Am J Psychiatry | 1971 | 5565851 | Yes |
873 | 1698 | 1698.0 | 37.34 | 37.3 | CpG motifs in bacterial DNA and their immune effects. | Arthur M Krieg | Annu Rev Immunol | 2002 | 11861616 | No |
874 | 3396 | 1698.0 | 122.5 | 61.2 | SPSS and SAS procedures for estimating indirect effects in simple mediation models. | Kristopher J Preacher, Andrew F Hayes | Behav Res Methods Instrum Comput | 2004 | 15641418 | Yes |
875 | 1697 | 1697.0 | 47.61 | 47.6 | Negative refraction makes a perfect lens | Pendry | Phys Rev Lett | 2000 | 11041972 | Yes |
876 | 3391 | 1695.5 | 104.68 | 52.3 | Organization and expression of eucaryotic split genes coding for proteins. | R Breathnach, P Chambon | Annu Rev Biochem | 1981 | 6791577 | No |
877 | 1695 | 1695.0 | 0.0 | 0.0 | The membrane actions of anesthetics and tranquilizers. | P Seeman | Pharmacol Rev | 1972 | 4565956 | No |
878 | 3389 | 1694.5 | 146.22 | 73.1 | The attention system of the human brain. | M I Posner, S E Petersen | Annu Rev Neurosci | 1990 | 2183676 | No |
879 | 1694 | 1694.0 | 52.86 | 52.9 | The nuclear factor NF-kappaB pathway in inflammation. | Toby Lawrence | Cold Spring Harb Perspect Biol | 2009 | 20457564 | No |
880 | 3378 | 1689.0 | 71.41 | 35.7 | Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. | Rudolf Jaenisch, Adrian Bird | Nat Genet | 2003 | 12610534 | No |
881 | 1688 | 1688.0 | 47.12 | 47.1 | Dopamine, learning and motivation. | Roy A Wise | Nat Rev Neurosci | 2004 | 15152198 | No |
882 | 3371 | 1685.5 | 110.63 | 55.3 | A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. | Y Matsumura, H Maeda | Cancer Res | 1986 | 2946403 | Yes |
883 | 5054 | 1684.7 | 111.5 | 37.2 | EMBOSS: the European Molecular Biology Open Software Suite. | P Rice, I Longden, A Bleasby | Trends Genet | 2000 | 10827456 | Yes |
884 | 1684 | 1684.0 | 71.58 | 71.6 | Secretory products of macrophages. | C F Nathan | J Clin Invest | 1987 | 3543052 | No |
885 | 1683 | 1683.0 | 55.06 | 55.1 | Superoxide radical and superoxide dismutases. | I Fridovich | Annu Rev Biochem | 1995 | 7574505 | No |
886 | 1682 | 1682.0 | 40.02 | 40.0 | Theta oscillations in the hippocampus. | György Buzsáki | Neuron | 2002 | 11832222 | No |
887 | 6722 | 1680.5 | 183.54 | 45.9 | Matrix elasticity directs stem cell lineage specification. | Adam J Engler, Shamik Sen, H Lee Sweeney, Dennis E Discher | Cell | 2006 | 16923388 | Yes |
888 | 3352 | 1676.0 | 100.95 | 50.5 | Function and activation of NF-kappa B in the immune system. | P A Baeuerle, T Henkel | Annu Rev Immunol | 1994 | 8011280 | No |
889 | 1676 | 1676.0 | 64.68 | 64.7 | Eye movements in reading and information processing: 20 years of research. | K Rayner | Psychol Bull | 1998 | 9849112 | No |
890 | 1676 | 1676.0 | 43.07 | 43.1 | Pathways towards and away from Alzheimer's disease. | Mark P Mattson | Nature | 2004 | 15295589 | No |
891 | 1675 | 1675.0 | 40.98 | 41.0 | Defensins: antimicrobial peptides of innate immunity. | Tomas Ganz | Nat Rev Immunol | 2003 | 12949495 | No |
892 | 3349 | 1674.5 | 71.86 | 35.9 | Smad-dependent and Smad-independent pathways in TGF-beta family signalling. | Rik Derynck, Ying E Zhang | Nature | 2003 | 14534577 | No |
893 | 5022 | 1674.0 | 178.64 | 59.5 | Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. | C E Murry, R B Jennings, K A Reimer | Circulation | 1986 | 3769170 | Yes |
894 | 1674 | 1674.0 | 0.0 | 0.0 | MECHANISM OF SUSTAINED-ACTION MEDICATION. THEORETICAL ANALYSIS OF RATE OF RELEASE OF SOLID DRUGS DISPERSED IN SOLID MATRICES. | T HIGUCHI | J Pharm Sci | 1963 | 14088963 | Yes |
895 | 1673 | 1673.0 | 43.87 | 43.9 | Animal mitochondrial genomes. | J L Boore | Nucleic Acids Res | 1999 | 10101183 | No |
896 | 1673 | 1673.0 | 54.87 | 54.9 | The importance of selenium to human health. | M P Rayman | Lancet | 2000 | 10963212 | No |
897 | 1673 | 1673.0 | 37.68 | 37.7 | Metastasis to bone: causes, consequences and therapeutic opportunities. | Gregory R Mundy | Nat Rev Cancer | 2002 | 12154351 | No |
898 | 3345 | 1672.5 | 0.0 | 0.0 | Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid. | A C Chang, S N Cohen | J Bacteriol | 1978 | 149110 | Yes |
899 | 1672 | 1672.0 | 77.18 | 77.2 | Specific impairments of planning. | T Shallice | Philos Trans R Soc Lond B Biol Sci | 1982 | 6125971 | Yes |
900 | 15040 | 1671.1 | 1063.63 | 118.2 | Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. | Jacques Ferlay, Isabelle Soerjomataram, Rajesh Dikshit, Sultan Eser, Colin Mathers, Marise Rebelo, Donald Maxwell Parkin, David Forman, Freddie Bray | Int J Cancer | 2015 | 25220842 | Yes |
901 | 1670 | 1670.0 | 60.96 | 61.0 | Fetal origins of coronary heart disease. | D J Barker | BMJ | 1995 | 7613432 | No |
902 | 5010 | 1670.0 | 128.48 | 42.8 | A new statistical method for haplotype reconstruction from population data. | M Stephens, N J Smith, P Donnelly | Am J Hum Genet | 2001 | 11254454 | Yes |
903 | 1670 | 1670.0 | 0.0 | 0.0 | On respiratory impairment in cancer cells. | O WARBURG | Science | 1956 | 13351639 | Yes |
904 | 5009 | 1669.7 | 175.64 | 58.5 | Arlequin (version 3.0): an integrated software package for population genetics data analysis. | Laurent Excoffier, Guillaume Laval, Stefan Schneider | Evol Bioinform Online | 2007 | 19325852 | Yes |
905 | 1669 | 1669.0 | 69.75 | 69.8 | Human error: models and management. | J Reason | BMJ | 2000 | 10720363 | Yes |
906 | 1668 | 1668.0 | 31.7 | 31.7 | Mechanisms of alternative pre-messenger RNA splicing. | Douglas L Black | Annu Rev Biochem | 2003 | 12626338 | No |
907 | 1667 | 1667.0 | 59.35 | 59.4 | Calbindin D-28k and parvalbumin in the rat nervous system. | M R Celio | Neuroscience | 1990 | 2199841 | Yes |
908 | 1666 | 1666.0 | 79.77 | 79.8 | Missing data analysis: making it work in the real world. | John W Graham | Annu Rev Psychol | 2009 | 18652544 | No |
909 | 4995 | 1665.0 | 182.5 | 60.8 | Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. | C Lord, M Rutter, A Le Couteur | J Autism Dev Disord | 1994 | 7814313 | Yes |
910 | 3329 | 1664.5 | 88.75 | 44.4 | The acute respiratory distress syndrome. | L B Ware, M A Matthay | N Engl J Med | 2000 | 10793167 | No |
911 | 4993 | 1664.3 | 172.01 | 57.3 | The brain's default network: anatomy, function, and relevance to disease. | Randy L Buckner, Jessica R Andrews-Hanna, Daniel L Schacter | Ann N Y Acad Sci | 2008 | 18400922 | No |
912 | 1664 | 1664.0 | 83.88 | 83.9 | A systematic method for clinical description and classification of personality variants. A proposal. | C R Cloninger | Arch Gen Psychiatry | 1987 | 3579504 | Yes |
913 | 1663 | 1663.0 | 36.64 | 36.6 | Approaching the asymptote? Evolution and revolution in immunology. | C A Janeway | Cold Spring Harb Symp Quant Biol | 1989 | 2700931 | No |
914 | 1663 | 1663.0 | 56.79 | 56.8 | Hybrid porous solids: past, present, future. | Gérard Férey | Chem Soc Rev | 2008 | 18197340 | Yes |
915 | 1663 | 1663.0 | 48.39 | 48.4 | Mechanisms of hepatic fibrogenesis. | Scott L Friedman | Gastroenterology | 2008 | 18471545 | No |
916 | 1662 | 1662.0 | 50.49 | 50.5 | The blood-brain barrier in health and chronic neurodegenerative disorders. | Berislav V Zlokovic | Neuron | 2008 | 18215617 | No |
917 | 3323 | 1661.5 | 0.0 | 0.0 | Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. | J V Durnin, J Womersley | Br J Nutr | 1974 | 4843734 | Yes |
918 | 4983 | 1661.0 | 147.55 | 49.2 | GUS fusions: beta-glucuronidase as a sensitive and versatile gene fusion marker in higher plants. | R A Jefferson, T A Kavanagh, M W Bevan | EMBO J | 1987 | 3327686 | Yes |
919 | 1661 | 1661.0 | 55.8 | 55.8 | Determination and analysis of urea and guanidine hydrochloride denaturation curves. | C N Pace | Methods Enzymol | 1986 | 3773761 | Yes |
920 | 3320 | 1660.0 | 98.32 | 49.2 | Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions. | M Nei, T Gojobori | Mol Biol Evol | 1986 | 3444411 | Yes |
921 | 3319 | 1659.5 | 105.51 | 52.8 | Distributed hierarchical processing in the primate cerebral cortex. | D J Felleman, D C Van Essen | Cereb Cortex | 1991 | 1822724 | No |
922 | 1659 | 1659.0 | 78.95 | 79.0 | The Resonating Valence Bond State in La2CuO4 and Superconductivity. | P W Anderson | Science | 1987 | 17818979 | Yes |
923 | 3314 | 1657.0 | 0.0 | 0.0 | A diagnostic interview: the schedule for affective disorders and schizophrenia. | J Endicott, R L Spitzer | Arch Gen Psychiatry | 1978 | 678037 | Yes |
924 | 1657 | 1657.0 | 36.58 | 36.6 | The complex language of chromatin regulation during transcription. | Shelley L Berger | Nature | 2007 | 17522673 | No |
925 | 4967 | 1655.7 | 188.3 | 62.8 | Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction data. | L Excoffier, P E Smouse, J M Quattro | Genetics | 1992 | 1644282 | Yes |
926 | 3310 | 1655.0 | 93.37 | 46.7 | Cutaneous wound healing. | A J Singer, R A Clark | N Engl J Med | 1999 | 10471461 | No |
927 | 3307 | 1653.5 | 97.92 | 49.0 | Regulation of the mevalonate pathway. | J L Goldstein, M S Brown | Nature | 1990 | 1967820 | No |
928 | 4960 | 1653.3 | 126.65 | 42.2 | APE: Analyses of Phylogenetics and Evolution in R language. | Emmanuel Paradis, Julien Claude, Korbinian Strimmer | Bioinformatics | 2004 | 14734327 | Yes |
929 | 1652 | 1652.0 | 35.6 | 35.6 | Signalling pathways of the TNF superfamily: a double-edged sword. | Bharat B Aggarwal | Nat Rev Immunol | 2003 | 12949498 | No |
930 | 1651 | 1651.0 | 39.18 | 39.2 | XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density. | D E McRee | J Struct Biol | 1999 | 10222271 | Yes |
931 | 3300 | 1650.0 | 93.87 | 46.9 | The endophenotype concept in psychiatry: etymology and strategic intentions. | Irving I Gottesman, Todd D Gould | Am J Psychiatry | 2003 | 12668349 | No |
932 | 1649 | 1649.0 | 51.66 | 51.7 | Epidemiology of insomnia: what we know and what we still need to learn. | Maurice M Ohayon | Sleep Med Rev | 2002 | 12531146 | Yes |
933 | 3297 | 1648.5 | 107.48 | 53.7 | A simple and very efficient method for generating cDNA libraries. | U Gubler, B J Hoffman | Gene | 1983 | 6198242 | Yes |
934 | 1648 | 1648.0 | 34.44 | 34.4 | In situ hybridization: an improved whole-mount method for Xenopus embryos. | R M Harland | Methods Cell Biol | 1991 | 1811161 | Yes |
935 | 11533 | 1647.6 | 284.64 | 40.7 | Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. | Jo Vandesompele, Katleen De Preter, Filip Pattyn, Bruce Poppe, Nadine Van Roy, Anne De Paepe, Frank Speleman | Genome Biol | 2002 | 12184808 | Yes |
936 | 3292 | 1646.0 | 198.17 | 99.1 | Stress, social support, and the buffering hypothesis. | S Cohen, T A Wills | Psychol Bull | 1985 | 3901065 | No |
937 | 1646 | 1646.0 | 43.89 | 43.9 | DAMPs, PAMPs and alarmins: all we need to know about danger. | Marco E Bianchi | J Leukoc Biol | 2007 | 17032697 | No |
938 | 3290 | 1645.0 | 68.34 | 34.2 | The fundamental role of epigenetic events in cancer. | Peter A Jones, Stephen B Baylin | Nat Rev Genet | 2002 | 12042769 | No |
939 | 1645 | 1645.0 | 48.52 | 48.5 | Standardized low-resolution brain electromagnetic tomography (sLORETA): technical details. | R D Pascual-Marqui | Methods Find Exp Clin Pharmacol | 2002 | 12575463 | No |
940 | 1644 | 1644.0 | 34.73 | 34.7 | Systems biology: a brief overview. | Hiroaki Kitano | Science | 2002 | 11872829 | No |
941 | 1643 | 1643.0 | 0.0 | 0.0 | Analysis of bacteriophage T7 early RNAs and proteins on slab gels. | F W Studier | J Mol Biol | 1973 | 4760132 | Yes |
942 | 3286 | 1643.0 | 69.65 | 34.8 | Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. | M Karin, Y Ben-Neriah | Annu Rev Immunol | 2000 | 10837071 | No |
943 | 1643 | 1643.0 | 59.31 | 59.3 | Hazards of heavy metal contamination. | Lars Järup | Br Med Bull | 2003 | 14757716 | No |
944 | 1642 | 1642.0 | 49.81 | 49.8 | Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. | Gökhan S Hotamisligil | Cell | 2010 | 20303879 | No |
945 | 1641 | 1641.0 | 45.8 | 45.8 | The structure and regulation of protein phosphatases. | P Cohen | Annu Rev Biochem | 1989 | 2549856 | No |
946 | 3282 | 1641.0 | 382.15 | 191.1 | A Guideline of Selecting and Reporting Intraclass Correlation Coefficients for Reliability Research. | Terry K Koo, Mae Y Li | J Chiropr Med | 2016 | 27330520 | Yes |
947 | 1639 | 1639.0 | 0.0 | 0.0 | A GENERALIZED WILCOXON TEST FOR COMPARING ARBITRARILY SINGLY-CENSORED SAMPLES. | E A GEHAN | Biometrika | 1965 | 14341275 | Yes |
948 | 1639 | 1639.0 | 38.85 | 38.9 | TRP channels as cellular sensors. | David E Clapham | Nature | 2003 | 14654832 | No |
949 | 1637 | 1637.0 | 67.57 | 67.6 | Simplified calculation of body-surface area. | R D Mosteller | N Engl J Med | 1987 | 3657876 | Yes |
950 | 1635 | 1635.0 | 0.0 | 0.0 | Transplacental carcinogenesis by stilbestrol. | J Folkman | N Engl J Med | 1971 | 5556579 | Yes |
951 | 1633 | 1633.0 | 36.38 | 36.4 | Protein modules and signalling networks. | T Pawson | Nature | 1995 | 7531822 | No |
952 | 1633 | 1633.0 | 37.0 | 37.0 | The expanding role of mitochondria in apoptosis. | X Wang | Genes Dev | 2001 | 11711427 | No |
953 | 3263 | 1631.5 | 0.0 | 0.0 | Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril. | P J Fraker, J C Speck | Biochem Biophys Res Commun | 1978 | 637870 | Yes |
954 | 3263 | 1631.5 | 107.87 | 53.9 | A receptor-mediated pathway for cholesterol homeostasis. | M S Brown, J L Goldstein | Science | 1986 | 3513311 | No |
955 | 3261 | 1630.5 | 0.0 | 0.0 | High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study. | M N Berry, D S Friend | J Cell Biol | 1969 | 4900611 | Yes |
956 | 1630 | 1630.0 | 45.68 | 45.7 | Protein kinase C and lipid signaling for sustained cellular responses. | Y Nishizuka | FASEB J | 1995 | 7737456 | No |
957 | 1630 | 1630.0 | 47.16 | 47.2 | Mechanisms and genes of cellular suicide. | H Steller | Science | 1995 | 7878463 | No |
958 | 1630 | 1630.0 | 36.04 | 36.0 | Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. | R J Kaufman | Genes Dev | 1999 | 10346810 | No |
959 | 1630 | 1630.0 | 0.0 | 0.0 | Efficient trace-labelling of proteins with iodine. | A S McFARLANE | Nature | 1958 | 13566175 | Yes |
960 | 1630 | 1630.0 | 49.9 | 49.9 | The physiology of glucagon-like peptide 1. | Jens Juul Holst | Physiol Rev | 2007 | 17928588 | No |
961 | 1629 | 1629.0 | 74.69 | 74.7 | Determination of glutathione and glutathione disulfide in biological samples. | M E Anderson | Methods Enzymol | 1985 | 4088074 | Yes |
962 | 1629 | 1629.0 | 38.34 | 38.3 | Mechanisms of intracellular protein transport. | J E Rothman | Nature | 1994 | 7969419 | No |
963 | 1629 | 1629.0 | 39.61 | 39.6 | The immunopathogenesis of sepsis. | Jonathan Cohen | Nature | 2002 | 12490963 | No |
964 | 1629 | 1629.0 | 56.82 | 56.8 | TGFβ signalling in context. | Joan Massagué | Nat Rev Mol Cell Biol | 2012 | 22992590 | No |
965 | 3256 | 1628.0 | 82.91 | 41.5 | The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. | A J Ridley, A Hall | Cell | 1992 | 1643657 | Yes |
966 | 1627 | 1627.0 | 0.0 | 0.0 | Diffusion-in-gel methods for immunological analysis. | O OUCHTERLONY | Prog Allergy | 1958 | 13578996 | Yes |
967 | 4872 | 1624.0 | 98.65 | 32.9 | Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. | Jason D Fontenot, Marc A Gavin, Alexander Y Rudensky | Nat Immunol | 2003 | 12612578 | Yes |
968 | 1623 | 1623.0 | 0.0 | 0.0 | The hydrolysis of rabbit y-globulin and antibodies with crystalline papain. | R R PORTER | Biochem J | 1959 | 14434282 | Yes |
969 | 1623 | 1623.0 | 45.52 | 45.5 | A theory of cortical responses. | Karl Friston | Philos Trans R Soc Lond B Biol Sci | 2005 | 15937014 | No |
970 | 1623 | 1623.0 | 59.31 | 59.3 | The free-energy principle: a unified brain theory? | Karl Friston | Nat Rev Neurosci | 2010 | 20068583 | No |
971 | 3245 | 1622.5 | 143.01 | 71.5 | Extracellular vesicles: exosomes, microvesicles, and friends. | Graça Raposo, Willem Stoorvogel | J Cell Biol | 2013 | 23420871 | No |
972 | 3244 | 1622.0 | 93.12 | 46.6 | Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. | P J Barnes, M Karin | N Engl J Med | 1997 | 9091804 | No |
973 | 3243 | 1621.5 | 92.2 | 46.1 | Leptin and the regulation of body weight in mammals. | J M Friedman, J L Halaas | Nature | 1998 | 9796811 | No |
974 | 4862 | 1620.7 | 162.69 | 54.2 | Quantum mechanical continuum solvation models. | Jacopo Tomasi, Benedetta Mennucci, Roberto Cammi | Chem Rev | 2005 | 16092826 | Yes |
975 | 1619 | 1619.0 | 82.0 | 82.0 | Predicting basal metabolic rate, new standards and review of previous work. | W N Schofield | Hum Nutr Clin Nutr | 1985 | 4044297 | Yes |
976 | 1618 | 1618.0 | 62.49 | 62.5 | An empirical correction for absorption anisotropy. | R H Blessing | Acta Crystallogr A | 1995 | 7702794 | Yes |
977 | 3234 | 1617.0 | 88.63 | 44.3 | Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. | Michael T Lin, M Flint Beal | Nature | 2006 | 17051205 | No |
978 | 1612 | 1612.0 | 87.2 | 87.2 | The quality of care. How can it be assessed? | A Donabedian | JAMA | 1988 | 3045356 | No |
979 | 1612 | 1612.0 | 0.0 | 0.0 | Protein denaturation. | C Tanford | Adv Protein Chem | 1968 | 4882248 | No |
980 | 1610 | 1610.0 | 81.25 | 81.2 | Role of Streptococcus mutans in human dental decay. | W J Loesche | Microbiol Rev | 1986 | 3540569 | No |
981 | 1610 | 1610.0 | 40.55 | 40.5 | Cellular mechanisms of insulin resistance. | G I Shulman | J Clin Invest | 2000 | 10903330 | No |
982 | 1609 | 1609.0 | 86.67 | 86.7 | The Children's Depression, Inventory (CDI). | M Kovacs | Psychopharmacol Bull | 1985 | 4089116 | Yes |
983 | 1609 | 1609.0 | 44.41 | 44.4 | Calcium signaling. | D E Clapham | Cell | 1995 | 7834745 | No |
984 | 3216 | 1608.0 | 0.0 | 0.0 | On the size of the active site in proteases. I. Papain. | I Schechter, A Berger | Biochem Biophys Res Commun | 1967 | 6035483 | Yes |
985 | 1608 | 1608.0 | 44.43 | 44.4 | The mitogen-activated protein kinase signal transduction pathway. | R J Davis | J Biol Chem | 1993 | 8325833 | No |
986 | 1607 | 1607.0 | 42.93 | 42.9 | The global health burden of infection-associated cancers in the year 2002. | Donald Maxwell Parkin | Int J Cancer | 2006 | 16404738 | Yes |
987 | 3208 | 1604.0 | 81.08 | 40.5 | Base-calling of automated sequencer traces using phred. II. Error probabilities. | B Ewing, P Green | Genome Res | 1998 | 9521922 | Yes |
988 | 1604 | 1604.0 | 34.5 | 34.5 | Antiviral actions of interferons. | C E Samuel | Clin Microbiol Rev | 2001 | 11585785 | No |
989 | 1603 | 1603.0 | 55.69 | 55.7 | Formation and Structure of Self-Assembled Monolayers. | Abraham Ulman | Chem Rev | 1996 | 11848802 | Yes |
990 | 1602 | 1602.0 | 52.3 | 52.3 | Patterns of amino acids near signal-sequence cleavage sites. | G von Heijne | Eur J Biochem | 1983 | 6852022 | Yes |
991 | 1601 | 1601.0 | 39.35 | 39.4 | Neutrophils and immunity: challenges and opportunities. | Carl Nathan | Nat Rev Immunol | 2006 | 16498448 | No |
992 | 1601 | 1601.0 | 44.97 | 45.0 | Follicular helper CD4 T cells (TFH). | Shane Crotty | Annu Rev Immunol | 2011 | 21314428 | No |
993 | 3198 | 1599.0 | 0.0 | 0.0 | The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin. | J A Spudich, S Watt | J Biol Chem | 1971 | 4254541 | Yes |
994 | 1599 | 1599.0 | 46.18 | 46.2 | Flow-mediated endothelial mechanotransduction. | P F Davies | Physiol Rev | 1995 | 7624393 | No |
995 | 3198 | 1599.0 | 64.06 | 32.0 | Rho GTPases in cell biology. | Sandrine Etienne-Manneville, Alan Hall | Nature | 2002 | 12478284 | No |
996 | 3198 | 1599.0 | 0.0 | 0.0 | Loss of recent memory after bilateral hippocampal lesions. | W B SCOVILLE, B MILNER | J Neurol Neurosurg Psychiatry | 1957 | 13406589 | Yes |
997 | 4795 | 1598.3 | 151.08 | 50.4 | Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. | F E Harrell, K L Lee, D B Mark | Stat Med | 1996 | 8668867 | No |
998 | 1598 | 1598.0 | 64.01 | 64.0 | Plant products as antimicrobial agents. | M M Cowan | Clin Microbiol Rev | 1999 | 10515903 | No |
999 | 3192 | 1596.0 | 97.8 | 48.9 | Alzheimer's disease: the amyloid cascade hypothesis. | J A Hardy, G A Higgins | Science | 1992 | 1566067 | No |
1000 | 1596 | 1596.0 | 0.0 | 0.0 | The fractionation of high-molecular-weight ribonucleic acid by polyacrylamide-gel electrophoresis. | U E Loening | Biochem J | 1967 | 5339944 | Yes |
1001 | 1596 | 1596.0 | 86.98 | 87.0 | A clinically based classification system for acute pancreatitis. Summary of the International Symposium on Acute Pancreatitis, Atlanta, Ga, September 11 through 13, 1992. | E L Bradley | Arch Surg | 1993 | 8489394 | No |
1002 | 1595 | 1595.0 | 0.0 | 0.0 | Analysis of tissue and arterial blood temperatures in the resting human forearm. | H H PENNES | J Appl Physiol | 1948 | 18887578 | Yes |
1003 | 6373 | 1593.2 | 139.97 | 35.0 | WebLogo: a sequence logo generator. | Gavin E Crooks, Gary Hon, John-Marc Chandonia, Steven E Brenner | Genome Res | 2004 | 15173120 | Yes |
1004 | 1593 | 1593.0 | 36.96 | 37.0 | Developmental regulation of the growth plate. | Henry M Kronenberg | Nature | 2003 | 12748651 | No |
1005 | 1591 | 1591.0 | 31.69 | 31.7 | Signaling--2000 and beyond. | T Hunter | Cell | 2000 | 10647936 | No |
1006 | 1591 | 1591.0 | 36.34 | 36.3 | Role of angiogenesis in tumor growth and metastasis. | Judah Folkman | Semin Oncol | 2002 | 12516034 | No |
1007 | 3177 | 1588.5 | 86.44 | 43.2 | Measuring the thickness of the human cerebral cortex from magnetic resonance images. | B Fischl, A M Dale | Proc Natl Acad Sci U S A | 2000 | 10984517 | Yes |
1008 | 1588 | 1588.0 | 40.24 | 40.2 | A clearer vision for in vivo imaging. | R Weissleder | Nat Biotechnol | 2001 | 11283581 | No |
1009 | 3176 | 1588.0 | 93.51 | 46.8 | Protein structure prediction on the Web: a case study using the Phyre server. | Lawrence A Kelley, Michael J E Sternberg | Nat Protoc | 2009 | 19247286 | Yes |
1010 | 1587 | 1587.0 | 32.58 | 32.6 | Notch signalling: a simple pathway becomes complex. | Sarah J Bray | Nat Rev Mol Cell Biol | 2006 | 16921404 | No |
1011 | 1586 | 1586.0 | 64.14 | 64.1 | The use of a plus-maze to measure anxiety in the mouse. | R G Lister | Psychopharmacology (Berl) | 1987 | 3110839 | Yes |
1012 | 1585 | 1585.0 | 41.18 | 41.2 | Targeting PI3K signalling in cancer: opportunities, challenges and limitations. | Jeffrey A Engelman | Nat Rev Cancer | 2009 | 19629070 | No |
1013 | 1584 | 1584.0 | 29.99 | 30.0 | The regulation of E2F by pRB-family proteins. | N Dyson | Genes Dev | 1998 | 9694791 | No |
1014 | 1579 | 1579.0 | 80.08 | 80.1 | Calmodulin plays a pivotal role in cellular regulation. | W Y Cheung | Science | 1980 | 6243188 | No |
1015 | 1577 | 1577.0 | 0.0 | 0.0 | Notes on sugar determination. | M SMOGYI | J Biol Chem | 1952 | 14938350 | Yes |
1016 | 4729 | 1576.3 | 117.51 | 39.2 | Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. | Michael W Pfaffl, Graham W Horgan, Leo Dempfle | Nucleic Acids Res | 2002 | 11972351 | Yes |
1017 | 1576 | 1576.0 | 49.07 | 49.1 | The molecular pathology of Alzheimer's disease. | D J Selkoe | Neuron | 1991 | 1673054 | No |
1018 | 1575 | 1575.0 | 62.27 | 62.3 | Social cognitive theory: an agentic perspective. | A Bandura | Annu Rev Psychol | 2001 | 11148297 | Yes |
1019 | 1575 | 1575.0 | 34.0 | 34.0 | DNA topoisomerases: structure, function, and mechanism. | J J Champoux | Annu Rev Biochem | 2001 | 11395412 | No |
1020 | 1575 | 1575.0 | 29.86 | 29.9 | Automated electron microscope tomography using robust prediction of specimen movements. | David N Mastronarde | J Struct Biol | 2005 | 16182563 | Yes |
1021 | 3150 | 1575.0 | 0.0 | 0.0 | Judgment under Uncertainty: Heuristics and Biases. | A Tversky, D Kahneman | Science | 1974 | 17835457 | Yes |
1022 | 1574 | 1574.0 | 64.79 | 64.8 | Health consequences of intimate partner violence. | Jacquelyn C Campbell | Lancet | 2002 | 11965295 | No |
1023 | 14156 | 1572.9 | 317.31 | 35.3 | Cytoscape: a software environment for integrated models of biomolecular interaction networks. | Paul Shannon, Andrew Markiel, Owen Ozier, Nitin S Baliga, Jonathan T Wang, Daniel Ramage, Nada Amin, Benno Schwikowski, Trey Ideker | Genome Res | 2003 | 14597658 | Yes |
1024 | 1572 | 1572.0 | 0.0 | 0.0 | The catecholamine hypothesis of affective disorders: a review of supporting evidence. | J J Schildkraut | Am J Psychiatry | 1965 | 5319766 | No |
1025 | 3143 | 1571.5 | 180.77 | 90.4 | Stages and processes of self-change of smoking: toward an integrative model of change. | J O Prochaska, C C DiClemente | J Consult Clin Psychol | 1983 | 6863699 | Yes |
1026 | 3143 | 1571.5 | 83.1 | 41.5 | The future of genetic studies of complex human diseases. | N Risch, K Merikangas | Science | 1996 | 8801636 | Yes |
1027 | 1570 | 1570.0 | 36.62 | 36.6 | Thrombin signalling and protease-activated receptors. | S R Coughlin | Nature | 2000 | 11001069 | No |
1028 | 1569 | 1569.0 | 0.0 | 0.0 | Evaluating the quality of medical care. | A Donabedian | Milbank Mem Fund Q | 1966 | 5338568 | No |
1029 | 1567 | 1567.0 | 48.32 | 48.3 | Hepatitis B virus infection. | W M Lee | N Engl J Med | 1997 | 9392700 | No |
1030 | 1567 | 1567.0 | 78.58 | 78.6 | Approximate entropy as a measure of system complexity. | S M Pincus | Proc Natl Acad Sci U S A | 1991 | 11607165 | Yes |
1031 | 1567 | 1567.0 | 45.28 | 45.3 | Breast cancer and hormone-replacement therapy in the Million Women Study. | Valerie Beral | Lancet | 2003 | 12927427 | Yes |
1032 | 1567 | 1567.0 | 33.18 | 33.2 | MicroRNA biogenesis: coordinated cropping and dicing. | V Narry Kim | Nat Rev Mol Cell Biol | 2005 | 15852042 | No |
1033 | 1567 | 1567.0 | 45.74 | 45.7 | The extracellular matrix: not just pretty fibrils. | Richard O Hynes | Science | 2009 | 19965464 | No |
1034 | 1566 | 1566.0 | 66.33 | 66.3 | Prooxidant states and tumor promotion. | P A Cerutti | Science | 1985 | 2981433 | No |
1035 | 1563 | 1563.0 | 0.0 | 0.0 | Inositol phospholipids and cell surface receptor function. | R H Michell | Biochim Biophys Acta | 1975 | 164246 | No |
1036 | 1563 | 1563.0 | 43.75 | 43.8 | Cancer chemoprevention with dietary phytochemicals. | Young-Joon Surh | Nat Rev Cancer | 2003 | 14570043 | No |
1037 | 4688 | 1562.7 | 184.15 | 61.4 | Parallel organization of functionally segregated circuits linking basal ganglia and cortex. | G E Alexander, M R DeLong, P L Strick | Annu Rev Neurosci | 1986 | 3085570 | No |
1038 | 1561 | 1561.0 | 48.83 | 48.8 | Bcl-2 and the regulation of programmed cell death. | J C Reed | J Cell Biol | 1994 | 8294493 | No |
1039 | 6240 | 1560.0 | 281.2 | 70.3 | The Fagerström Test for Nicotine Dependence: a revision of the Fagerström Tolerance Questionnaire. | T F Heatherton, L T Kozlowski, R C Frecker, K O Fagerström | Br J Addict | 1991 | 1932883 | Yes |
1040 | 1560 | 1560.0 | 42.78 | 42.8 | Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. | G Trinchieri | Annu Rev Immunol | 1995 | 7612223 | No |
1041 | 3116 | 1558.0 | 70.87 | 35.4 | Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. | C D Nobes, A Hall | Cell | 1995 | 7536630 | Yes |
1042 | 10875 | 1553.6 | 278.8 | 39.8 | Induction of pluripotent stem cells from adult human fibroblasts by defined factors. | Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda, Shinya Yamanaka | Cell | 2007 | 18035408 | Yes |
1043 | 3104 | 1552.0 | 0.0 | 0.0 | Acetylornithinase of Escherichia coli: partial purification and some properties. | H J VOGEL, D M BONNER | J Biol Chem | 1956 | 13278318 | Yes |
1044 | 3100 | 1550.0 | 72.52 | 36.3 | Lessons from hereditary colorectal cancer. | K W Kinzler, B Vogelstein | Cell | 1996 | 8861899 | No |
1045 | 4646 | 1548.7 | 176.92 | 59.0 | Cell death: the significance of apoptosis. | A H Wyllie, J F Kerr, A R Currie | Int Rev Cytol | 1980 | 7014501 | No |
1046 | 3097 | 1548.5 | 72.2 | 36.1 | Cell death: critical control points. | Nika N Danial, Stanley J Korsmeyer | Cell | 2004 | 14744432 | No |
1047 | 17028 | 1548.0 | 374.05 | 34.0 | Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. | Aravind Subramanian, Pablo Tamayo, Vamsi K Mootha, Sayan Mukherjee, Benjamin L Ebert, Michael A Gillette, Amanda Paulovich, Scott L Pomeroy, Todd R Golub, Eric S Lander, Jill P Mesirov | Proc Natl Acad Sci U S A | 2005 | 16199517 | Yes |
1048 | 1548 | 1548.0 | 43.06 | 43.1 | Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. | Scott L Friedman | Physiol Rev | 2008 | 18195085 | No |
1049 | 3092 | 1546.0 | 0.0 | 0.0 | Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method. | R B Devereux, N Reichek | Circulation | 1977 | 138494 | Yes |
1050 | 1546 | 1546.0 | 76.77 | 76.8 | Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases. | B N Ames | Science | 1983 | 6351251 | No |
1051 | 6184 | 1546.0 | 166.3 | 41.6 | Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. | A Shevchenko, M Wilm, O Vorm, M Mann | Anal Chem | 1996 | 8779443 | Yes |
1052 | 1545 | 1545.0 | 0.0 | 0.0 | Transposition and fusion of the lac genes to selected promoters in Escherichia coli using bacteriophage lambda and Mu. | M J Casadaban | J Mol Biol | 1976 | 781293 | Yes |
1053 | 3090 | 1545.0 | 98.74 | 49.4 | The heat-shock proteins. | S Lindquist, E A Craig | Annu Rev Genet | 1988 | 2853609 | No |
1054 | 3088 | 1544.0 | 142.39 | 71.2 | The structure of negative emotional states: comparison of the Depression Anxiety Stress Scales (DASS) with the Beck Depression and Anxiety Inventories. | P F Lovibond, S H Lovibond | Behav Res Ther | 1995 | 7726811 | Yes |
1055 | 1544 | 1544.0 | 40.57 | 40.6 | Global cancer statistics in the year 2000. | D M Parkin | Lancet Oncol | 2001 | 11905707 | No |
1056 | 6172 | 1543.0 | 301.11 | 75.3 | A simple technique for quantitation of low levels of DNA damage in individual cells. | N P Singh, M T McCoy, R R Tice, E L Schneider | Exp Cell Res | 1988 | 3345800 | Yes |
1057 | 1543 | 1543.0 | 64.19 | 64.2 | Keratoconus. | Y S Rabinowitz | Surv Ophthalmol | 1998 | 9493273 | No |
1058 | 6168 | 1542.0 | 243.16 | 60.8 | Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. | A J Hughes, S E Daniel, L Kilford, A J Lees | J Neurol Neurosurg Psychiatry | 1992 | 1564476 | Yes |
1059 | 3084 | 1542.0 | 92.58 | 46.3 | Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. | G G Glenner, C W Wong | Biochem Biophys Res Commun | 1984 | 6375662 | Yes |
1060 | 1542 | 1542.0 | 36.43 | 36.4 | Exploring complex networks. | S H Strogatz | Nature | 2001 | 11258382 | No |
1061 | 3083 | 1541.5 | 97.58 | 48.8 | Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. | P Liang, A B Pardee | Science | 1992 | 1354393 | Yes |
1062 | 1541 | 1541.0 | 35.91 | 35.9 | Structure and regulation of voltage-gated Ca2+ channels. | W A Catterall | Annu Rev Cell Dev Biol | 2000 | 11031246 | No |
1063 | 1541 | 1541.0 | 44.73 | 44.7 | Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials. | Fiona Turnbull | Lancet | 2003 | 14615107 | Yes |
1064 | 1540 | 1540.0 | 38.56 | 38.6 | The distribution of secondary growths in cancer of the breast. 1889. | S Paget | Cancer Metastasis Rev | 1989 | 2673568 | No |
1065 | 1538 | 1538.0 | 0.0 | 0.0 | Zone electrophoresis in starch gels: group variations in the serum proteins of normal human adults. | O SMITHIES | Biochem J | 1955 | 13276348 | Yes |
1066 | 1538 | 1538.0 | 39.45 | 39.5 | Integrating cell-signalling pathways with NF-kappaB and IKK function. | Neil D Perkins | Nat Rev Mol Cell Biol | 2007 | 17183360 | No |
1067 | 1537 | 1537.0 | 42.96 | 43.0 | Evolutionary relationship of DNA sequences in finite populations. | F Tajima | Genetics | 1983 | 6628982 | Yes |
1068 | 4609 | 1536.3 | 186.9 | 62.3 | AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. | P G Reeves, F H Nielsen, G C Fahey | J Nutr | 1993 | 8229312 | No |
1069 | 1536 | 1536.0 | 57.01 | 57.0 | Inhibited spontaneous emission in solid-state physics and electronics. | Yablonovitch | Phys Rev Lett | 1987 | 10034639 | Yes |
1070 | 1535 | 1535.0 | 59.03 | 59.0 | ATP-regulated K+ channels in cardiac muscle. | A Noma | Nature | 1983 | 6310409 | Yes |
1071 | 1533 | 1533.0 | 0.0 | 0.0 | The plasma lecithins:cholesterol acyltransferase reaction. | J A Glomset | J Lipid Res | 1968 | 4868699 | No |
1072 | 3065 | 1532.5 | 0.0 | 0.0 | Some quantitative uses of drug antagonists. | O ARUNLAKSHANA, H O SCHILD | Br J Pharmacol Chemother | 1959 | 13651579 | Yes |
1073 | 1532 | 1532.0 | 55.95 | 56.0 | Protein oxidation and aging. | E R Stadtman | Science | 1992 | 1355616 | No |
1074 | 1531 | 1531.0 | 61.54 | 61.5 | Epidemiological features of chronic low-back pain. | G B Andersson | Lancet | 1999 | 10470716 | No |
1075 | 7645 | 1529.0 | 205.12 | 41.0 | Mapping and quantifying mammalian transcriptomes by RNA-Seq. | Ali Mortazavi, Brian A Williams, Kenneth McCue, Lorian Schaeffer, Barbara Wold | Nat Methods | 2008 | 18516045 | Yes |
1076 | 3055 | 1527.5 | 0.0 | 0.0 | A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. | R F BEERS, I W SIZER | J Biol Chem | 1952 | 14938361 | Yes |
1077 | 1525 | 1525.0 | 0.0 | 0.0 | Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? | J V NEEL | Am J Hum Genet | 1962 | 13937884 | Yes |
1078 | 3049 | 1524.5 | 71.44 | 35.7 | Monocyte and macrophage heterogeneity. | Siamon Gordon, Philip R Taylor | Nat Rev Immunol | 2005 | 16322748 | No |
1079 | 3047 | 1523.5 | 0.0 | 0.0 | A SIMPLIFIED LEAD CITRATE STAIN FOR USE IN ELECTRON MICROSCOPY. | J H VENABLE, R COGGESHALL | J Cell Biol | 1965 | 14287192 | Yes |
1080 | 1523 | 1523.0 | 59.14 | 59.1 | Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM. | R A DeFronzo | Diabetes | 1988 | 3289989 | No |
1081 | 1522 | 1522.0 | 47.38 | 47.4 | Accurate description of van der Waals complexes by density functional theory including empirical corrections. | Stefan Grimme | J Comput Chem | 2004 | 15224390 | Yes |
1082 | 3043 | 1521.5 | 167.98 | 84.0 | The Health Belief Model: a decade later. | N K Janz, M H Becker | Health Educ Q | 1984 | 6392204 | No |
1083 | 4553 | 1517.7 | 0.0 | 0.0 | Glucose clamp technique: a method for quantifying insulin secretion and resistance. | R A DeFronzo, J D Tobin, R Andres | Am J Physiol | 1979 | 382871 | Yes |
1084 | 1517 | 1517.0 | 53.7 | 53.7 | Excitotoxic cell death. | D W Choi | J Neurobiol | 1992 | 1361523 | No |
1085 | 6060 | 1515.0 | 170.99 | 42.7 | Epithelial-mesenchymal transitions in development and disease. | Jean Paul Thiery, Hervé Acloque, Ruby Y J Huang, M Angela Nieto | Cell | 2009 | 19945376 | No |
1086 | 1512 | 1512.0 | 0.0 | 0.0 | Removal of fatty acids from serum albumin by charcoal treatment. | R F Chen | J Biol Chem | 1967 | 6016603 | Yes |
1087 | 4535 | 1511.7 | 177.73 | 59.2 | Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire. | R L Spitzer, K Kroenke, J B Williams | JAMA | 1999 | 10568646 | Yes |
1088 | 3022 | 1511.0 | 79.0 | 39.5 | CAP3: A DNA sequence assembly program. | X Huang, A Madan | Genome Res | 1999 | 10508846 | Yes |
1089 | 1510 | 1510.0 | 34.19 | 34.2 | Molecular regulation of vessel maturation. | Rakesh K Jain | Nat Med | 2003 | 12778167 | No |
1090 | 3014 | 1507.0 | 0.0 | 0.0 | A complementation analysis of the restriction and modification of DNA in Escherichia coli. | H W Boyer, D Roulland-Dussoix | J Mol Biol | 1969 | 4896022 | Yes |
1091 | 1506 | 1506.0 | 51.78 | 51.8 | Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis. | A Dunaif | Endocr Rev | 1997 | 9408743 | No |
1092 | 1506 | 1506.0 | 32.59 | 32.6 | The synaptic vesicle cycle. | Thomas C Sudhof | Annu Rev Neurosci | 2004 | 15217342 | No |
1093 | 1505 | 1505.0 | 0.0 | 0.0 | SELECTION OF HYBRIDS FROM MATINGS OF FIBROBLASTS IN VITRO AND THEIR PRESUMED RECOMBINANTS. | J W LITTLEFIELD | Science | 1964 | 14168277 | Yes |
1094 | 1505 | 1505.0 | 47.45 | 47.5 | Intestinal mucosal barrier function in health and disease. | Jerrold R Turner | Nat Rev Immunol | 2009 | 19855405 | No |
1095 | 3009 | 1504.5 | 92.74 | 46.4 | Assembly of asparagine-linked oligosaccharides. | R Kornfeld, S Kornfeld | Annu Rev Biochem | 1985 | 3896128 | No |
1096 | 4512 | 1504.0 | 0.0 | 0.0 | Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test. | B N Ames, J Mccann, E Yamasaki | Mutat Res | 1975 | 768755 | Yes |
1097 | 1504 | 1504.0 | 36.31 | 36.3 | A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics. | J SantaLucia | Proc Natl Acad Sci U S A | 1998 | 9465037 | Yes |
1098 | 1504 | 1504.0 | 71.71 | 71.7 | Why patients use alternative medicine: results of a national study. | J A Astin | JAMA | 1998 | 9605899 | Yes |
1099 | 3007 | 1503.5 | 84.67 | 42.3 | A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation. | G Shaw, R Kamen | Cell | 1986 | 3488815 | Yes |
1100 | 3006 | 1503.0 | 97.43 | 48.7 | Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. | K D McCarthy, J de Vellis | J Cell Biol | 1980 | 6248568 | Yes |
1101 | 3005 | 1502.5 | 0.0 | 0.0 | Mathematical model for studying genetic variation in terms of restriction endonucleases. | M Nei, W H Li | Proc Natl Acad Sci U S A | 1979 | 291943 | Yes |
1102 | 1502 | 1502.0 | 0.0 | 0.0 | Mechanisms of action of transmitters and other substances on smooth muscle. | T B Bolton | Physiol Rev | 1979 | 37533 | No |
1103 | 1501 | 1501.0 | 84.72 | 84.7 | Detecting alcoholism. The CAGE questionnaire. | J A Ewing | JAMA | 1984 | 6471323 | Yes |
1104 | 1501 | 1501.0 | 41.08 | 41.1 | Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. | D Lavanchy | J Viral Hepat | 2004 | 14996343 | No |
1105 | 3002 | 1501.0 | 106.83 | 53.4 | Wnt/β-catenin signaling and disease. | Hans Clevers, Roel Nusse | Cell | 2012 | 22682243 | No |
1106 | 3001 | 1500.5 | 168.49 | 84.2 | The Brief Symptom Inventory: an introductory report. | L R Derogatis, N Melisaratos | Psychol Med | 1983 | 6622612 | Yes |
1107 | 1500 | 1500.0 | 30.6 | 30.6 | CD4+ CD25+ suppressor T cells: more questions than answers. | Ethan M Shevach | Nat Rev Immunol | 2002 | 12093005 | No |
1108 | 1499 | 1499.0 | 0.0 | 0.0 | Oxygen-dependent microbial killing by phagocytes (first of two parts). | B M Babior | N Engl J Med | 1978 | 24176 | Yes |
1109 | 1499 | 1499.0 | 104.69 | 104.7 | Determination and quantification of content validity. | M R Lynn | Nurs Res | 1986 | 3640358 | Yes |
1110 | 4487 | 1495.7 | 131.34 | 43.8 | Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. | G S Hotamisligil, N S Shargill, B M Spiegelman | Science | 1993 | 7678183 | Yes |
1111 | 1495 | 1495.0 | 0.0 | 0.0 | A theory of cerebellar cortex. | D Marr | J Physiol | 1969 | 5784296 | Yes |
1112 | 2988 | 1494.0 | 162.0 | 81.0 | The MOS social support survey. | C D Sherbourne, A L Stewart | Soc Sci Med | 1991 | 2035047 | Yes |
1113 | 1493 | 1493.0 | 39.65 | 39.6 | Metabolomics--the link between genotypes and phenotypes. | Oliver Fiehn | Plant Mol Biol | 2002 | 11860207 | No |
1114 | 1492 | 1492.0 | 51.22 | 51.2 | Genetic differentiation and estimation of gene flow from F-statistics under isolation by distance. | F Rousset | Genetics | 1997 | 9093870 | Yes |
1115 | 2981 | 1490.5 | 98.01 | 49.0 | Nonparametric statistical testing of EEG- and MEG-data. | Eric Maris, Robert Oostenveld | J Neurosci Methods | 2007 | 17517438 | Yes |
1116 | 1490 | 1490.0 | 0.0 | 0.0 | Dendritic organization in the neurons of the visual and motor cortices of the cat. | D A SHOLL | J Anat | 1953 | 13117757 | Yes |
1117 | 1490 | 1490.0 | 41.49 | 41.5 | The genetics of ageing. | Cynthia J Kenyon | Nature | 2010 | 20336132 | No |
1118 | 1488 | 1488.0 | 52.69 | 52.7 | The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. | G P Chrousos | N Engl J Med | 1995 | 7715646 | No |
1119 | 1487 | 1487.0 | 34.85 | 34.9 | Excitatory actions of gaba during development: the nature of the nurture. | Yehezkel Ben-Ari | Nat Rev Neurosci | 2002 | 12209121 | No |
1120 | 2973 | 1486.5 | 0.0 | 0.0 | Variations in pattern of pubertal changes in girls. | W A Marshall, J M Tanner | Arch Dis Child | 1969 | 5785179 | Yes |
1121 | 7431 | 1486.2 | 229.76 | 46.0 | Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. | Sarah Wild, Gojka Roglic, Anders Green, Richard Sicree, Hilary King | Diabetes Care | 2004 | 15111519 | Yes |
1122 | 2972 | 1486.0 | 91.29 | 45.6 | The inflammasomes. | Kate Schroder, Jurg Tschopp | Cell | 2010 | 20303873 | No |
1123 | 2972 | 1486.0 | 142.21 | 71.1 | miRBase: annotating high confidence microRNAs using deep sequencing data. | Ana Kozomara, Sam Griffiths-Jones | Nucleic Acids Res | 2014 | 24275495 | Yes |
1124 | 1484 | 1484.0 | 31.94 | 31.9 | DNA methylation and human disease. | Keith D Robertson | Nat Rev Genet | 2005 | 16136652 | No |
1125 | 1483 | 1483.0 | 0.0 | 0.0 | Comparison of the predicted and observed secondary structure of T4 phage lysozyme. | B W Matthews | Biochim Biophys Acta | 1975 | 1180967 | Yes |
1126 | 1483 | 1483.0 | 46.42 | 46.4 | Thioredoxin. | A Holmgren | Annu Rev Biochem | 1985 | 3896121 | No |
1127 | 1481 | 1481.0 | 103.26 | 103.3 | The assessment of clinical skills/competence/performance. | G E Miller | Acad Med | 1990 | 2400509 | Yes |
1128 | 1479 | 1479.0 | 0.0 | 0.0 | Changes in the visual system of monocularly sutured or enucleated cats demonstrable with cytochrome oxidase histochemistry. | M Wong-Riley | Brain Res | 1979 | 223730 | Yes |
1129 | 2958 | 1479.0 | 125.34 | 62.7 | The biofilm matrix. | Hans-Curt Flemming, Jost Wingender | Nat Rev Microbiol | 2010 | 20676145 | No |
1130 | 4432 | 1477.3 | 91.62 | 30.5 | Surfing the p53 network. | B Vogelstein, D Lane, A J Levine | Nature | 2000 | 11099028 | No |
1131 | 1477 | 1477.0 | 61.75 | 61.8 | Physiological actions of taurine. | R J Huxtable | Physiol Rev | 1992 | 1731369 | No |
1132 | 1477 | 1477.0 | 30.04 | 30.0 | Generating samples under a Wright-Fisher neutral model of genetic variation. | Richard R Hudson | Bioinformatics | 2002 | 11847089 | Yes |
1133 | 1476 | 1476.0 | 66.61 | 66.6 | Heavy metal intensification of DAB-based HRP reaction product. | J C Adams | J Histochem Cytochem | 1981 | 7252134 | Yes |
1134 | 1476 | 1476.0 | 30.13 | 30.1 | Cellular roles of DNA topoisomerases: a molecular perspective. | James C Wang | Nat Rev Mol Cell Biol | 2002 | 12042765 | No |
1135 | 2948 | 1474.0 | 89.15 | 44.6 | The mirror-neuron system. | Giacomo Rizzolatti, Laila Craighero | Annu Rev Neurosci | 2004 | 15217330 | No |
1136 | 1473 | 1473.0 | 0.0 | 0.0 | Presidential Address-1976. Social support as a moderator of life stress. | S Cobb | Psychosom Med | 1976 | 981490 | Yes |
1137 | 1473 | 1473.0 | 44.17 | 44.2 | Signal sequences. The limits of variation. | G von Heijne | J Mol Biol | 1985 | 4032478 | Yes |
1138 | 1473 | 1473.0 | 31.25 | 31.2 | Cancer and the chemokine network. | Fran Balkwill | Nat Rev Cancer | 2004 | 15229479 | No |
1139 | 2943 | 1471.5 | 0.0 | 0.0 | An efficient mRNA-dependent translation system from reticulocyte lysates. | H R Pelham, R J Jackson | Eur J Biochem | 1976 | 823012 | Yes |
1140 | 1471 | 1471.0 | 0.0 | 0.0 | A classification of hand preference by association analysis. | M Annett | Br J Psychol | 1970 | 5457503 | Yes |
1141 | 1471 | 1471.0 | 48.29 | 48.3 | Biofilms: microbial life on surfaces. | Rodney M Donlan | Emerg Infect Dis | 2002 | 12194761 | No |
1142 | 1471 | 1471.0 | 47.03 | 47.0 | The comet assay for DNA damage and repair: principles, applications, and limitations. | Andrew R Collins | Mol Biotechnol | 2004 | 15004294 | No |
1143 | 1471 | 1471.0 | 32.97 | 33.0 | Protein homology detection by HMM-HMM comparison. | Johannes Söding | Bioinformatics | 2005 | 15531603 | Yes |
1144 | 1469 | 1469.0 | 47.2 | 47.2 | Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic. | Robert E Marx | J Oral Maxillofac Surg | 2003 | 12966493 | Yes |
1145 | 2930 | 1465.0 | 74.25 | 37.1 | Identification of common molecular subsequences. | T F Smith, M S Waterman | J Mol Biol | 1981 | 7265238 | Yes |
1146 | 1465 | 1465.0 | 52.75 | 52.8 | A measure of population subdivision based on microsatellite allele frequencies. | M Slatkin | Genetics | 1995 | 7705646 | Yes |
1147 | 5860 | 1465.0 | 122.63 | 30.7 | Stem cells, cancer, and cancer stem cells. | T Reya, S J Morrison, M F Clarke, I L Weissman | Nature | 2001 | 11689955 | No |
1148 | 2928 | 1464.0 | 119.97 | 60.0 | Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. | G Di Chiara, A Imperato | Proc Natl Acad Sci U S A | 1988 | 2899326 | Yes |
1149 | 1463 | 1463.0 | 32.44 | 32.4 | The effect of infections on susceptibility to autoimmune and allergic diseases. | Jean-Francois Bach | N Engl J Med | 2002 | 12239261 | No |
1150 | 1462 | 1462.0 | 56.58 | 56.6 | An overview of brominated flame retardants in the environment. | Cynthia A de Wit | Chemosphere | 2002 | 11999784 | No |
1151 | 1461 | 1461.0 | 52.67 | 52.7 | Global epidemiology of oral and oropharyngeal cancer. | Saman Warnakulasuriya | Oral Oncol | 2009 | 18804401 | No |
1152 | 1460 | 1460.0 | 0.0 | 0.0 | Chemiosmotic coupling in oxidative and photosynthetic phosphorylation. | P Mitchell | Biol Rev Camb Philos Soc | 1966 | 5329743 | No |
1153 | 1460 | 1460.0 | 48.03 | 48.0 | Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis. | J Folkman | N Engl J Med | 1995 | 7491141 | No |
1154 | 1460 | 1460.0 | 38.22 | 38.2 | The synaptic vesicle cycle: a cascade of protein-protein interactions. | T C Südhof | Nature | 1995 | 7791897 | No |
1155 | 2918 | 1459.0 | 0.0 | 0.0 | Genetic regulatory mechanisms in the synthesis of proteins. | F JACOB, J MONOD | J Mol Biol | 1961 | 13718526 | Yes |
1156 | 1458 | 1458.0 | 44.18 | 44.2 | THE WATER-WATER CYCLE IN CHLOROPLASTS: Scavenging of Active Oxygens and Dissipation of Excess Photons. | Kozi Asada | Annu Rev Plant Physiol Plant Mol Biol | 1999 | 15012221 | Yes |
1157 | 1458 | 1458.0 | 35.8 | 35.8 | Recognition of microorganisms and activation of the immune response. | Ruslan Medzhitov | Nature | 2007 | 17943118 | No |
1158 | 1458 | 1458.0 | 57.83 | 57.8 | Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. | Sergio Pecorelli | Int J Gynaecol Obstet | 2009 | 19367689 | No |
1159 | 2915 | 1457.5 | 72.36 | 36.2 | Parkinson's disease: mechanisms and models. | William Dauer, Serge Przedborski | Neuron | 2003 | 12971891 | No |
1160 | 2915 | 1457.5 | 0.0 | 0.0 | PREPARATION OF FATTY ACID METHYL ESTERS AND DIMETHYLACETALS FROM LIPIDS WITH BORON FLUORIDE--METHANOL. | W R MORRISON, L M SMITH | J Lipid Res | 1964 | 14221106 | Yes |
1161 | 1457 | 1457.0 | 45.09 | 45.1 | Chlorpromazine equivalent doses for the newer atypical antipsychotics. | Scott W Woods | J Clin Psychiatry | 2003 | 12823080 | No |
1162 | 1456 | 1456.0 | 0.0 | 0.0 | Positional information and the spatial pattern of cellular differentiation. | L Wolpert | J Theor Biol | 1969 | 4390734 | Yes |
1163 | 2912 | 1456.0 | 59.06 | 29.5 | SIFT: Predicting amino acid changes that affect protein function. | Pauline C Ng, Steven Henikoff | Nucleic Acids Res | 2003 | 12824425 | Yes |
1164 | 1456 | 1456.0 | 50.55 | 50.5 | Social determinants of health inequalities. | Michael Marmot | Lancet | 2005 | 15781105 | Yes |
1165 | 1455 | 1455.0 | 35.81 | 35.8 | Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. | S L Friedman | J Biol Chem | 2000 | 10644669 | No |
1166 | 2909 | 1454.5 | 86.23 | 43.1 | Probing Single Molecules and Single Nanoparticles by Surface-Enhanced Raman Scattering | Nie, Emory | Science | 1997 | 9027306 | Yes |
1167 | 1454 | 1454.0 | 56.6 | 56.6 | Archaea in coastal marine environments. | E F DeLong | Proc Natl Acad Sci U S A | 1992 | 1608980 | Yes |
1168 | 1453 | 1453.0 | 56.39 | 56.4 | Diagnosis of Alzheimer's disease. | Z S Khachaturian | Arch Neurol | 1985 | 2864910 | Yes |
1169 | 2905 | 1452.5 | 75.59 | 37.8 | Liver fibrosis. | Ramón Bataller, David A Brenner | J Clin Invest | 2005 | 15690074 | No |
1170 | 1452 | 1452.0 | 38.23 | 38.2 | G1 events and regulation of cell proliferation. | A B Pardee | Science | 1989 | 2683075 | No |
1171 | 1452 | 1452.0 | 38.55 | 38.5 | Type III protein secretion systems in bacterial pathogens of animals and plants. | C J Hueck | Microbiol Mol Biol Rev | 1998 | 9618447 | No |
1172 | 4351 | 1450.3 | 152.87 | 51.0 | FastTree 2--approximately maximum-likelihood trees for large alignments. | Morgan N Price, Paramvir S Dehal, Adam P Arkin | PLoS One | 2010 | 20224823 | Yes |
1173 | 1450 | 1450.0 | 32.47 | 32.5 | Mechanisms of cancer drug resistance. | Michael M Gottesman | Annu Rev Med | 2002 | 11818492 | No |
1174 | 1448 | 1448.0 | 86.0 | 86.0 | Performance-oriented assessment of mobility problems in elderly patients. | M E Tinetti | J Am Geriatr Soc | 1986 | 3944402 | Yes |
1175 | 1448 | 1448.0 | 45.49 | 45.5 | MYC on the path to cancer. | Chi V Dang | Cell | 2012 | 22464321 | No |
1176 | 1447 | 1447.0 | 0.0 | 0.0 | A rating instrument for anxiety disorders. | W W Zung | Psychosomatics | 1971 | 5172928 | Yes |
1177 | 1447 | 1447.0 | 0.0 | 0.0 | A study of the adrenotropic receptors. | R P AHLQUIST | Am J Physiol | 1948 | 18882199 | Yes |
1178 | 1446 | 1446.0 | 38.29 | 38.3 | Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): trends and problems. | S A Bustin | J Mol Endocrinol | 2002 | 12200227 | No |
1179 | 1446 | 1446.0 | 35.44 | 35.4 | AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. | D Grahame Hardie | Nat Rev Mol Cell Biol | 2007 | 17712357 | No |
1180 | 2890 | 1445.0 | 94.35 | 47.2 | Biofilms: survival mechanisms of clinically relevant microorganisms. | Rodney M Donlan, J William Costerton | Clin Microbiol Rev | 2002 | 11932229 | No |
1181 | 1443 | 1443.0 | 54.34 | 54.3 | Grounded cognition. | Lawrence W Barsalou | Annu Rev Psychol | 2008 | 17705682 | No |
1182 | 2885 | 1442.5 | 75.11 | 37.6 | Neuronal oscillations in cortical networks. | György Buzsáki, Andreas Draguhn | Science | 2004 | 15218136 | No |
1183 | 1442 | 1442.0 | 0.0 | 0.0 | The molecular theory of polyelectrolyte solutions with applications to the electrostatic properties of polynucleotides. | G S Manning | Q Rev Biophys | 1978 | 353876 | No |
1184 | 1442 | 1442.0 | 40.49 | 40.5 | The dawning era of polymer therapeutics. | Ruth Duncan | Nat Rev Drug Discov | 2003 | 12750738 | No |
1185 | 1441 | 1441.0 | 0.0 | 0.0 | Fluorographic detection of radioactivity in polyacrylamide gels with the water-soluble fluor, sodium salicylate. | J P Chamberlain | Anal Biochem | 1979 | 543547 | Yes |
1186 | 10072 | 1438.9 | 445.89 | 63.7 | Assessing the quality of reports of randomized clinical trials: is blinding necessary? | A R Jadad, R A Moore, D Carroll, C Jenkinson, D J Reynolds, D J Gavaghan, H J McQuay | Control Clin Trials | 1996 | 8721797 | Yes |
1187 | 1438 | 1438.0 | 41.23 | 41.2 | Interfaces and the driving force of hydrophobic assembly. | David Chandler | Nature | 2005 | 16193038 | No |
1188 | 1438 | 1438.0 | 70.93 | 70.9 | Role of nrf2 in oxidative stress and toxicity. | Qiang Ma | Annu Rev Pharmacol Toxicol | 2013 | 23294312 | No |
1189 | 1437 | 1437.0 | 0.0 | 0.0 | The energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers. | D E Atkinson | Biochemistry | 1968 | 4972613 | Yes |
1190 | 2873 | 1436.5 | 83.81 | 41.9 | Receptors for purines and pyrimidines. | V Ralevic, G Burnstock | Pharmacol Rev | 1998 | 9755289 | No |
1191 | 2873 | 1436.5 | 67.52 | 33.8 | Insulin signalling and the regulation of glucose and lipid metabolism. | A R Saltiel, C R Kahn | Nature | 2001 | 11742412 | Yes |
1192 | 2871 | 1435.5 | 0.0 | 0.0 | Periodate-lysine-paraformaldehyde fixative. A new fixation for immunoelectron microscopy. | I W McLean, P K Nakane | J Histochem Cytochem | 1974 | 4374474 | Yes |
1193 | 1435 | 1435.0 | 48.8 | 48.8 | PsychoPy--Psychophysics software in Python. | Jonathan W Peirce | J Neurosci Methods | 2007 | 17254636 | Yes |
1194 | 1434 | 1434.0 | 56.33 | 56.3 | Sick individuals and sick populations. | G Rose | Int J Epidemiol | 1985 | 3872850 | Yes |
1195 | 1434 | 1434.0 | 51.69 | 51.7 | Hypoxia-inducible factors in physiology and medicine. | Gregg L Semenza | Cell | 2012 | 22304911 | No |
1196 | 2867 | 1433.5 | 95.31 | 47.7 | Insulin-like growth factors and their binding proteins: biological actions. | J I Jones, D R Clemmons | Endocr Rev | 1995 | 7758431 | No |
1197 | 4300 | 1433.3 | 124.38 | 41.5 | Canonical sampling through velocity rescaling. | Giovanni Bussi, Davide Donadio, Michele Parrinello | J Chem Phys | 2007 | 17212484 | Yes |
1198 | 1433 | 1433.0 | 28.11 | 28.1 | Maximum-likelihood density modification. | T C Terwilliger | Acta Crystallogr D Biol Crystallogr | 2000 | 10944333 | Yes |
1199 | 1432 | 1432.0 | 43.81 | 43.8 | Interleukin-2: inception, impact, and implications. | K A Smith | Science | 1988 | 3131876 | No |
1200 | 1432 | 1432.0 | 36.91 | 36.9 | Chemokines. | B J Rollins | Blood | 1997 | 9242519 | No |
1201 | 1432 | 1432.0 | 48.34 | 48.3 | Risk and safety of repetitive transcranial magnetic stimulation: report and suggested guidelines from the International Workshop on the Safety of Repetitive Transcranial Magnetic Stimulation, June 5-7, 1996. | E M Wassermann | Electroencephalogr Clin Neurophysiol | 1998 | 9474057 | No |
1202 | 1432 | 1432.0 | 40.57 | 40.6 | Clinical application of C-reactive protein for cardiovascular disease detection and prevention. | Paul M Ridker | Circulation | 2003 | 12551853 | No |
1203 | 2863 | 1431.5 | 107.99 | 54.0 | Angiogenic factors. | J Folkman, M Klagsbrun | Science | 1987 | 2432664 | No |
1204 | 4294 | 1431.3 | 180.2 | 60.1 | featureCounts: an efficient general purpose program for assigning sequence reads to genomic features. | Yang Liao, Gordon K Smyth, Wei Shi | Bioinformatics | 2014 | 24227677 | Yes |
1205 | 1431 | 1431.0 | 0.0 | 0.0 | Purinergic nerves. | G Burnstock | Pharmacol Rev | 1972 | 4404211 | No |
1206 | 5721 | 1430.2 | 257.56 | 64.4 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | J Clin Epidemiol | 2009 | 19631508 | No |
1207 | 1430 | 1430.0 | 77.68 | 77.7 | A rating scale for drug-induced akathisia. | T R Barnes | Br J Psychiatry | 1989 | 2574607 | Yes |
1208 | 1430 | 1430.0 | 0.0 | 0.0 | Towards a network theory of the immune system. | N K Jerne | Ann Immunol (Paris) | 1974 | 4142565 | No |
1209 | 2860 | 1430.0 | 121.2 | 60.6 | Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. | M H Zweig, G Campbell | Clin Chem | 1993 | 8472349 | No |
1210 | 1429 | 1429.0 | 39.72 | 39.7 | Inflammatory bowel disease: etiology and pathogenesis. | C Fiocchi | Gastroenterology | 1998 | 9649475 | No |
1211 | 1429 | 1429.0 | 43.06 | 43.1 | What is cognitive reserve? Theory and research application of the reserve concept. | Yaakov Stern | J Int Neuropsychol Soc | 2002 | 11939702 | No |
1212 | 5715 | 1428.8 | 144.42 | 36.1 | Transformation of intact yeast cells treated with alkali cations. | H Ito, Y Fukuda, K Murata, A Kimura | J Bacteriol | 1983 | 6336730 | Yes |
1213 | 1428 | 1428.0 | 62.42 | 62.4 | Recognition-by-components: a theory of human image understanding. | Irving Biederman | Psychol Rev | 1987 | 3575582 | Yes |
1214 | 2855 | 1427.5 | 67.24 | 33.6 | Integrin signaling. | F G Giancotti, E Ruoslahti | Science | 1999 | 10446041 | No |
1215 | 5710 | 1427.5 | 160.82 | 40.2 | Cancer-related inflammation. | Alberto Mantovani, Paola Allavena, Antonio Sica, Frances Balkwill | Nature | 2008 | 18650914 | No |
1216 | 5710 | 1427.5 | 235.39 | 58.8 | SignalP 4.0: discriminating signal peptides from transmembrane regions. | Thomas Nordahl Petersen, Søren Brunak, Gunnar von Heijne, Henrik Nielsen | Nat Methods | 2011 | 21959131 | Yes |
1217 | 2854 | 1427.0 | 70.06 | 35.0 | Raster3D: photorealistic molecular graphics. | E A Merritt, D J Bacon | Methods Enzymol | 1997 | 18488322 | Yes |
1218 | 2852 | 1426.0 | 120.02 | 60.0 | Oxygen toxicity, oxygen radicals, transition metals and disease. | B Halliwell, J M Gutteridge | Biochem J | 1984 | 6326753 | No |
1219 | 4275 | 1425.0 | 119.08 | 39.7 | Rapid and efficient site-specific mutagenesis without phenotypic selection. | T A Kunkel, J D Roberts, R A Zakour | Methods Enzymol | 1987 | 3323813 | Yes |
1220 | 1425 | 1425.0 | 38.71 | 38.7 | Angiogenesis: an organizing principle for drug discovery? | Judah Folkman | Nat Rev Drug Discov | 2007 | 17396134 | No |
1221 | 2850 | 1425.0 | 90.12 | 45.1 | The unfolded protein response: from stress pathway to homeostatic regulation. | Peter Walter, David Ron | Science | 2011 | 22116877 | No |
1222 | 2849 | 1424.5 | 78.79 | 39.4 | Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. | Christian Haass, Dennis J Selkoe | Nat Rev Mol Cell Biol | 2007 | 17245412 | No |
1223 | 4273 | 1424.3 | 96.19 | 32.1 | A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays. | Zhang, Chung, Oldenburg | J Biomol Screen | 1999 | 10838414 | Yes |
1224 | 2848 | 1424.0 | 84.52 | 42.3 | Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. | Steven E Nissen, Kathy Wolski | N Engl J Med | 2007 | 17517853 | Yes |
1225 | 2847 | 1423.5 | 100.24 | 50.1 | Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. | B J Marshall, J R Warren | Lancet | 1984 | 6145023 | Yes |
1226 | 2847 | 1423.5 | 109.27 | 54.6 | Efficient pseudopotentials for plane-wave calculations. | Troullier, Martins | Phys Rev B Condens Matter | 1991 | 9997467 | Yes |
1227 | 2846 | 1423.0 | 0.0 | 0.0 | Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. | J G Rheinwald, H Green | Cell | 1975 | 1052771 | Yes |
1228 | 1423 | 1423.0 | 49.99 | 50.0 | Classification of inflammatory bowel disease. | J E Lennard-Jones | Scand J Gastroenterol Suppl | 1989 | 2617184 | Yes |
1229 | 1423 | 1423.0 | 33.63 | 33.6 | Neuronal calcium signaling. | M J Berridge | Neuron | 1998 | 9697848 | No |
1230 | 2846 | 1423.0 | 104.87 | 52.4 | Long-range corrected hybrid density functionals with damped atom-atom dispersion corrections. | Jeng-Da Chai, Martin Head-Gordon | Phys Chem Chem Phys | 2008 | 18989472 | Yes |
1231 | 1422 | 1422.0 | 34.1 | 34.1 | Bone morphogenetic proteins: multifunctional regulators of vertebrate development. | B L Hogan | Genes Dev | 1996 | 8682290 | No |
1232 | 1421 | 1421.0 | 38.91 | 38.9 | Episodic memory: from mind to brain. | Endel Tulving | Annu Rev Psychol | 2002 | 11752477 | Yes |
1233 | 2840 | 1420.0 | 75.0 | 37.5 | Amino acid substitution matrices from protein blocks. | S Henikoff, J G Henikoff | Proc Natl Acad Sci U S A | 1992 | 1438297 | Yes |
1234 | 2835 | 1417.5 | 107.43 | 53.7 | Understanding interobserver agreement: the kappa statistic. | Anthony J Viera, Joanne M Garrett | Fam Med | 2005 | 15883903 | Yes |
1235 | 1417 | 1417.0 | 29.28 | 29.3 | Network motifs: theory and experimental approaches. | Uri Alon | Nat Rev Genet | 2007 | 17510665 | No |
1236 | 1416 | 1416.0 | 42.6 | 42.6 | Neurotrophins and neuronal plasticity. | H Thoenen | Science | 1995 | 7570017 | No |
1237 | 1416 | 1416.0 | 41.86 | 41.9 | An index to quantify an individual's scientific research output. | J E Hirsch | Proc Natl Acad Sci U S A | 2005 | 16275915 | Yes |
1238 | 2830 | 1415.0 | 81.99 | 41.0 | Matrix metalloproteinases. | H Nagase, J F Woessner | J Biol Chem | 1999 | 10419448 | No |
1239 | 1415 | 1415.0 | 41.44 | 41.4 | Drug-like properties and the causes of poor solubility and poor permeability. | C A Lipinski | J Pharmacol Toxicol Methods | 2000 | 11274893 | No |
1240 | 1415 | 1415.0 | 63.94 | 63.9 | Doxil®--the first FDA-approved nano-drug: lessons learned. | Yechezkel Barenholz | J Control Release | 2012 | 22484195 | No |
1241 | 2827 | 1413.5 | 99.63 | 49.8 | New perspectives in cell adhesion: RGD and integrins. | E Ruoslahti, M D Pierschbacher | Science | 1987 | 2821619 | No |
1242 | 1413 | 1413.0 | 56.2 | 56.2 | Guided Search 2.0 A revised model of visual search. | J M Wolfe | Psychon Bull Rev | 1994 | 24203471 | Yes |
1243 | 2819 | 1409.5 | 87.35 | 43.7 | Cloned glutamate receptors. | M Hollmann, S Heinemann | Annu Rev Neurosci | 1994 | 8210177 | No |
1244 | 1409 | 1409.0 | 35.95 | 36.0 | The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. | Michael R Lieber | Annu Rev Biochem | 2010 | 20192759 | No |
1245 | 2816 | 1408.0 | 67.16 | 33.6 | The epigenomics of cancer. | Peter A Jones, Stephen B Baylin | Cell | 2007 | 17320506 | No |
1246 | 1407 | 1407.0 | 56.65 | 56.6 | Calculation of substrate oxidation rates in vivo from gaseous exchange. | K N Frayn | J Appl Physiol Respir Environ Exerc Physiol | 1983 | 6618956 | Yes |
1247 | 1406 | 1406.0 | 58.88 | 58.9 | Drugs of abuse: anatomy, pharmacology and function of reward pathways. | G F Koob | Trends Pharmacol Sci | 1992 | 1604710 | No |
1248 | 2812 | 1406.0 | 71.77 | 35.9 | Protein structure comparison by alignment of distance matrices. | L Holm, C Sander | J Mol Biol | 1993 | 8377180 | Yes |
1249 | 1406 | 1406.0 | 30.15 | 30.1 | Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. | Judith Campisi | Cell | 2005 | 15734683 | No |
1250 | 4217 | 1405.7 | 221.96 | 74.0 | HISAT: a fast spliced aligner with low memory requirements. | Daehwan Kim, Ben Langmead, Steven L Salzberg | Nat Methods | 2015 | 25751142 | Yes |
1251 | 1405 | 1405.0 | 69.16 | 69.2 | Reliability and validity studies of the WHO--Composite International Diagnostic Interview (CIDI): a critical review. | H U Wittchen | J Psychiatr Res | 1994 | 8064641 | No |
1252 | 1405 | 1405.0 | 36.75 | 36.8 | Getting formal with dopamine and reward. | Wolfram Schultz | Neuron | 2002 | 12383780 | No |
1253 | 5615 | 1403.8 | 153.07 | 38.3 | Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. | C A Lipinski, F Lombardo, B W Dominy, P J Feeney | Adv Drug Deliv Rev | 2001 | 11259830 | No |
1254 | 1403 | 1403.0 | 28.76 | 28.8 | The microRNA Registry. | Sam Griffiths-Jones | Nucleic Acids Res | 2004 | 14681370 | Yes |
1255 | 1402 | 1402.0 | 0.0 | 0.0 | Thickness, cross-sectional areas and depth of invasion in the prognosis of cutaneous melanoma. | A Breslow | Ann Surg | 1970 | 5477666 | Yes |
1256 | 1400 | 1400.0 | 66.22 | 66.2 | Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury. | D R Janero | Free Radic Biol Med | 1990 | 2079232 | No |
1257 | 5594 | 1398.5 | 246.39 | 61.6 | Statistical power analyses using G*Power 3.1: tests for correlation and regression analyses. | Franz Faul, Edgar Erdfelder, Axel Buchner, Albert-Georg Lang | Behav Res Methods | 2009 | 19897823 | Yes |
1258 | 4193 | 1397.7 | 113.78 | 37.9 | Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. | Prateek Kumar, Steven Henikoff, Pauline C Ng | Nat Protoc | 2009 | 19561590 | Yes |
1259 | 1397 | 1397.0 | 0.0 | 0.0 | High-speed scanning in human memory. | S Sternberg | Science | 1966 | 5939936 | Yes |
1260 | 2794 | 1397.0 | 75.71 | 37.9 | Origins and Mechanisms of miRNAs and siRNAs. | Richard W Carthew, Erik J Sontheimer | Cell | 2009 | 19239886 | No |
1261 | 1394 | 1394.0 | 45.7 | 45.7 | Perceptual symbol systems. | L W Barsalou | Behav Brain Sci | 1999 | 11301525 | No |
1262 | 4180 | 1393.3 | 112.33 | 37.4 | Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. | A Nicholls, K A Sharp, B Honig | Proteins | 1991 | 1758883 | Yes |
1263 | 4180 | 1393.3 | 120.96 | 40.3 | Median-joining networks for inferring intraspecific phylogenies. | H J Bandelt, P Forster, A Röhl | Mol Biol Evol | 1999 | 10331250 | Yes |
1264 | 1393 | 1393.0 | 0.0 | 0.0 | Evolutionary rate at the molecular level. | M Kimura | Nature | 1968 | 5637732 | Yes |
1265 | 1392 | 1392.0 | 37.82 | 37.8 | Cellular basis of working memory. | P S Goldman-Rakic | Neuron | 1995 | 7695894 | No |
1266 | 9734 | 1390.6 | 279.84 | 40.0 | Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. | William C Knowler, Elizabeth Barrett-Connor, Sarah E Fowler, Richard F Hamman, John M Lachin, Elizabeth A Walker, David M Nathan | N Engl J Med | 2002 | 11832527 | Yes |
1267 | 1389 | 1389.0 | 43.22 | 43.2 | Oxidative stress and neurodegeneration: where are we now? | Barry Halliwell | J Neurochem | 2006 | 16805774 | No |
1268 | 1389 | 1389.0 | 36.84 | 36.8 | Tumor angiogenesis. | Robert S Kerbel | N Engl J Med | 2008 | 18463380 | No |
1269 | 1388 | 1388.0 | 33.7 | 33.7 | The caveolae membrane system. | R G Anderson | Annu Rev Biochem | 1998 | 9759488 | No |
1270 | 4161 | 1387.0 | 127.57 | 42.5 | Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. | Z N Oltvai, C L Milliman, S J Korsmeyer | Cell | 1993 | 8358790 | Yes |
1271 | 1387 | 1387.0 | 39.32 | 39.3 | Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. | M J Meaney | Annu Rev Neurosci | 2001 | 11520931 | No |
1272 | 1387 | 1387.0 | 36.18 | 36.2 | The retinal pigment epithelium in visual function. | Olaf Strauss | Physiol Rev | 2005 | 15987797 | No |
1273 | 1386 | 1386.0 | 79.38 | 79.4 | Role of endothelium in responses of vascular smooth muscle. | R F Furchgott | Circ Res | 1983 | 6313250 | No |
1274 | 1386 | 1386.0 | 31.61 | 31.6 | Points of control in inflammation. | Carl Nathan | Nature | 2002 | 12490957 | No |
1275 | 5543 | 1385.8 | 0.0 | 0.0 | Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. | D J Sahn, A DeMaria, J Kisslo, A Weyman | Circulation | 1978 | 709763 | Yes |
1276 | 5542 | 1385.5 | 217.66 | 54.4 | A brief measure for assessing generalized anxiety disorder: the GAD-7. | Robert L Spitzer, Kurt Kroenke, Janet B W Williams, Bernd Löwe | Arch Intern Med | 2006 | 16717171 | Yes |
1277 | 1385 | 1385.0 | 35.68 | 35.7 | Fabrication of novel biomaterials through molecular self-assembly. | Shuguang Zhang | Nat Biotechnol | 2003 | 14520402 | No |
1278 | 2769 | 1384.5 | 84.88 | 42.4 | Dali server: conservation mapping in 3D. | Liisa Holm, Päivi Rosenström | Nucleic Acids Res | 2010 | 20457744 | Yes |
1279 | 2768 | 1384.0 | 115.52 | 57.8 | ITS primers with enhanced specificity for basidiomycetes--application to the identification of mycorrhizae and rusts. | M Gardes, T D Bruns | Mol Ecol | 1993 | 8180733 | Yes |
1280 | 1384 | 1384.0 | 43.06 | 43.1 | Molecular dissection of reactive astrogliosis and glial scar formation. | Michael V Sofroniew | Trends Neurosci | 2009 | 19782411 | No |
1281 | 1382 | 1382.0 | 38.63 | 38.6 | Effects of cytochalasin and phalloidin on actin. | J A Cooper | J Cell Biol | 1987 | 3312229 | No |
1282 | 1382 | 1382.0 | 29.57 | 29.6 | Hox genes in vertebrate development. | R Krumlauf | Cell | 1994 | 7913880 | No |
1283 | 1382 | 1382.0 | 0.0 | 0.0 | EVIDENCE FOR THE EXISTENCE OF MONOAMINE NEURONS IN THE CENTRAL NERVOUS SYSTEM. IV. DISTRIBUTION OF MONOAMINE NERVE TERMINALS IN THE CENTRAL NERVOUS SYSTEM. | K FUXE | Acta Physiol Scand Suppl | 1965 | 14319769 | Yes |
1284 | 2763 | 1381.5 | 89.05 | 44.5 | Event-related EEG/MEG synchronization and desynchronization: basic principles. | G Pfurtscheller, F H Lopes da Silva | Clin Neurophysiol | 1999 | 10576479 | No |
1285 | 1381 | 1381.0 | 39.74 | 39.7 | Network pharmacology: the next paradigm in drug discovery. | Andrew L Hopkins | Nat Chem Biol | 2008 | 18936753 | No |
1286 | 1381 | 1381.0 | 45.22 | 45.2 | Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus. | Ralph A Defronzo | Diabetes | 2009 | 19336687 | No |
1287 | 2761 | 1380.5 | 105.46 | 52.7 | Macrophage plasticity and polarization: in vivo veritas. | Antonio Sica, Alberto Mantovani | J Clin Invest | 2012 | 22378047 | No |
1288 | 1380 | 1380.0 | 33.74 | 33.7 | PLANT COLD ACCLIMATION: Freezing Tolerance Genes and Regulatory Mechanisms. | Michael F. Thomashow | Annu Rev Plant Physiol Plant Mol Biol | 1999 | 15012220 | Yes |
1289 | 2760 | 1380.0 | 60.05 | 30.0 | Upstream and downstream of mTOR. | Nissim Hay, Nahum Sonenberg | Genes Dev | 2004 | 15314020 | No |
1290 | 1380 | 1380.0 | 36.88 | 36.9 | Growth of the plant cell wall. | Daniel J Cosgrove | Nat Rev Mol Cell Biol | 2005 | 16261190 | No |
1291 | 1380 | 1380.0 | 42.68 | 42.7 | What we can do and what we cannot do with fMRI. | Nikos K Logothetis | Nature | 2008 | 18548064 | No |
1292 | 1379 | 1379.0 | 52.17 | 52.2 | The role of positive emotions in positive psychology. The broaden-and-build theory of positive emotions. | B L Fredrickson | Am Psychol | 2001 | 11315248 | Yes |
1293 | 1378 | 1378.0 | 0.0 | 0.0 | The Gingival Index, the Plaque Index and the Retention Index Systems. | H Löe | J Periodontol | 1967 | 5237684 | Yes |
1294 | 1378 | 1378.0 | 28.22 | 28.2 | Switching and signaling at the telomere. | E H Blackburn | Cell | 2001 | 11572773 | No |
1295 | 2755 | 1377.5 | 0.0 | 0.0 | Maturation of the head of bacteriophage T4. I. DNA packaging events. | U K Laemmli, M Favre | J Mol Biol | 1973 | 4204102 | Yes |
1296 | 1377 | 1377.0 | 0.0 | 0.0 | Oogenesis in Xenopus laevis (Daudin). I. Stages of oocyte development in laboratory maintained animals. | J N Dumont | J Morphol | 1972 | 4109871 | Yes |
1297 | 1377 | 1377.0 | 57.43 | 57.4 | Glutamate: a neurotransmitter in mammalian brain. | F Fonnum | J Neurochem | 1984 | 6139418 | No |
1298 | 1377 | 1377.0 | 76.28 | 76.3 | Microplastics in the marine environment. | Anthony L Andrady | Mar Pollut Bull | 2011 | 21742351 | No |
1299 | 1376 | 1376.0 | 24.0 | 24.0 | Neuronal specification in the spinal cord: inductive signals and transcriptional codes. | T M Jessell | Nat Rev Genet | 2000 | 11262869 | No |
1300 | 1375 | 1375.0 | 52.28 | 52.3 | Interleukin-1 and interleukin-1 antagonism. | C A Dinarello | Blood | 1991 | 1826616 | No |
1301 | 1375 | 1375.0 | 35.04 | 35.0 | DNA topoisomerases. | J C Wang | Annu Rev Biochem | 1996 | 8811192 | No |
1302 | 1375 | 1375.0 | 39.78 | 39.8 | Adipose tissue, adipokines, and inflammation. | Giamila Fantuzzi | J Allergy Clin Immunol | 2005 | 15867843 | No |
1303 | 2747 | 1373.5 | 85.27 | 42.6 | Ab initio molecular-dynamics simulation of the liquid-metal-amorphous-semiconductor transition in germanium. | Kresse, Hafner | Phys Rev B Condens Matter | 1994 | 10010505 | Yes |
1304 | 2746 | 1373.0 | 94.71 | 47.4 | Inositol phosphates and cell signalling. | M J Berridge, R F Irvine | Nature | 1989 | 2550825 | No |
1305 | 1373 | 1373.0 | 68.19 | 68.2 | Perception of risk. | P Slovic | Science | 1987 | 3563507 | Yes |
1306 | 6865 | 1373.0 | 162.96 | 32.6 | Stages of embryonic development of the zebrafish. | C B Kimmel, W W Ballard, S R Kimmel, B Ullmann, T F Schilling | Dev Dyn | 1995 | 8589427 | Yes |
1307 | 1373 | 1373.0 | 44.8 | 44.8 | The basal ganglia: focused selection and inhibition of competing motor programs. | J W Mink | Prog Neurobiol | 1996 | 9004351 | No |
1308 | 4119 | 1373.0 | 108.86 | 36.3 | Inflammation and atherosclerosis. | Peter Libby, Paul M Ridker, Attilio Maseri | Circulation | 2002 | 11877368 | No |
1309 | 1373 | 1373.0 | 39.96 | 40.0 | Using circular dichroism spectra to estimate protein secondary structure. | Norma J Greenfield | Nat Protoc | 2006 | 17406547 | Yes |
1310 | 2746 | 1373.0 | 73.22 | 36.6 | The BCL-2 protein family: opposing activities that mediate cell death. | Richard J Youle, Andreas Strasser | Nat Rev Mol Cell Biol | 2008 | 18097445 | No |
1311 | 1372 | 1372.0 | 0.0 | 0.0 | Mode of cell migration to the superficial layers of fetal monkey neocortex. | P Rakic | J Comp Neurol | 1972 | 4624784 | Yes |
1312 | 1372 | 1372.0 | 40.13 | 40.1 | Dengue and dengue hemorrhagic fever. | D J Gubler | Clin Microbiol Rev | 1998 | 9665979 | No |
1313 | 2744 | 1372.0 | 62.63 | 31.3 | Signaling to NF-kappaB. | Matthew S Hayden, Sankar Ghosh | Genes Dev | 2004 | 15371334 | No |
1314 | 15091 | 1371.9 | 424.68 | 38.6 | PLINK: a tool set for whole-genome association and population-based linkage analyses. | Shaun Purcell, Benjamin Neale, Kathe Todd-Brown, Lori Thomas, Manuel A R Ferreira, David Bender, Julian Maller, Pamela Sklar, Paul I W de Bakker, Mark J Daly, Pak C Sham | Am J Hum Genet | 2007 | 17701901 | Yes |
1315 | 2742 | 1371.0 | 75.25 | 37.6 | The Fas death factor. | S Nagata, P Golstein | Science | 1995 | 7533326 | No |
1316 | 1370 | 1370.0 | 52.19 | 52.2 | The stress response in fish. | S E Wendelaar Bonga | Physiol Rev | 1997 | 9234959 | No |
1317 | 2740 | 1370.0 | 76.11 | 38.1 | A scaling normalization method for differential expression analysis of RNA-seq data. | Mark D Robinson, Alicia Oshlack | Genome Biol | 2010 | 20196867 | Yes |
1318 | 1370 | 1370.0 | 34.0 | 34.0 | The hippo signaling pathway in development and cancer. | Duojia Pan | Dev Cell | 2010 | 20951342 | No |
1319 | 1368 | 1368.0 | 26.42 | 26.4 | Cyclin-dependent kinases: engines, clocks, and microprocessors. | D O Morgan | Annu Rev Cell Dev Biol | 1997 | 9442875 | No |
1320 | 1367 | 1367.0 | 47.23 | 47.2 | The in vitro micronucleus technique. | M Fenech | Mutat Res | 2000 | 11113469 | No |
1321 | 1367 | 1367.0 | 47.93 | 47.9 | Introduction and General Overview of Cyclodextrin Chemistry. | József Szejtli | Chem Rev | 1998 | 11848947 | Yes |
1322 | 2734 | 1367.0 | 72.13 | 36.1 | PRODRG: a tool for high-throughput crystallography of protein-ligand complexes. | Alexander W Schüttelkopf, Daan M F van Aalten | Acta Crystallogr D Biol Crystallogr | 2004 | 15272157 | Yes |
1323 | 1366 | 1366.0 | 47.11 | 47.1 | Flavonoids as antioxidants. | P G Pietta | J Nat Prod | 2000 | 10924197 | No |
1324 | 1364 | 1364.0 | 44.03 | 44.0 | Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution. | H LeVine | Protein Sci | 1993 | 8453378 | Yes |
1325 | 8179 | 1363.2 | 176.73 | 29.5 | Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. | A Fire, S Xu, M K Montgomery, S A Kostas, S E Driver, C C Mello | Nature | 1998 | 9486653 | Yes |
1326 | 1363 | 1363.0 | 46.68 | 46.7 | New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. | R Y Tsien | Biochemistry | 1980 | 6770893 | Yes |
1327 | 1363 | 1363.0 | 47.13 | 47.1 | Multiple imputation: a primer. | J L Schafer | Stat Methods Med Res | 1999 | 10347857 | No |
1328 | 1363 | 1363.0 | 60.4 | 60.4 | Carboxylate-assisted transition-metal-catalyzed C-H bond functionalizations: mechanism and scope. | Lutz Ackermann | Chem Rev | 2011 | 21391562 | Yes |
1329 | 5449 | 1362.2 | 115.81 | 29.0 | A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. | B M Bolstad, R A Irizarry, M Astrand, T P Speed | Bioinformatics | 2003 | 12538238 | Yes |
1330 | 4086 | 1362.0 | 213.69 | 71.2 | The MOS 36-Item Short-Form Health Survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. | C A McHorney, J E Ware, A E Raczek | Med Care | 1993 | 8450681 | Yes |
1331 | 1360 | 1360.0 | 0.0 | 0.0 | A METHOD OF MEASURING EYE MOVEMENT USING A SCLERAL SEARCH COIL IN A MAGNETIC FIELD. | D A ROBINSON | IEEE Trans Biomed Eng | 1963 | 14121113 | Yes |
1332 | 2717 | 1358.5 | 0.0 | 0.0 | EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS. | A DAHLSTROEM, K FUXE | Acta Physiol Scand Suppl | 1964 | 14229500 | Yes |
1333 | 1358 | 1358.0 | 28.09 | 28.1 | Neuroblastoma: biological insights into a clinical enigma. | Garrett M Brodeur | Nat Rev Cancer | 2003 | 12612655 | No |
1334 | 4071 | 1357.0 | 118.62 | 39.5 | Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. | Earl S Ford, Wayne H Giles, William H Dietz | JAMA | 2002 | 11790215 | Yes |
1335 | 1357 | 1357.0 | 33.32 | 33.3 | Trastuzumab--mechanism of action and use in clinical practice. | Clifford A Hudis | N Engl J Med | 2007 | 17611206 | No |
1336 | 2713 | 1356.5 | 64.9 | 32.5 | Fibroblasts in cancer. | Raghu Kalluri, Michael Zeisberg | Nat Rev Cancer | 2006 | 16572188 | No |
1337 | 1356 | 1356.0 | 44.1 | 44.1 | Porous scaffold design for tissue engineering. | Scott J Hollister | Nat Mater | 2005 | 16003400 | No |
1338 | 2711 | 1355.5 | 68.63 | 34.3 | The DNA-damage response in human biology and disease. | Stephen P Jackson, Jiri Bartek | Nature | 2009 | 19847258 | No |
1339 | 1355 | 1355.0 | 43.36 | 43.4 | Cell biology and molecular basis of denitrification. | W G Zumft | Microbiol Mol Biol Rev | 1997 | 9409151 | No |
1340 | 1355 | 1355.0 | 37.33 | 37.3 | Tricine-SDS-PAGE. | Hermann Schägger | Nat Protoc | 2006 | 17406207 | Yes |
1341 | 4062 | 1354.0 | 85.81 | 28.6 | T-Coffee: A novel method for fast and accurate multiple sequence alignment. | C Notredame, D G Higgins, J Heringa | J Mol Biol | 2000 | 10964570 | Yes |
1342 | 2706 | 1353.0 | 69.91 | 35.0 | Human mesenchymal stem cells modulate allogeneic immune cell responses. | Sudeepta Aggarwal, Mark F Pittenger | Blood | 2005 | 15494428 | Yes |
1343 | 1352 | 1352.0 | 36.25 | 36.2 | Maximum likelihood phylogenetic estimation from DNA sequences with variable rates over sites: approximate methods. | Z Yang | J Mol Evol | 1994 | 7932792 | Yes |
1344 | 2703 | 1351.5 | 0.0 | 0.0 | Plaque formation and isolation of pure lines with poliomyelitis viruses. | R DULBECCO, M VOGT | J Exp Med | 1954 | 13130792 | Yes |
1345 | 2702 | 1351.0 | 58.37 | 29.2 | Automated MAD and MIR structure solution. | T C Terwilliger, J Berendzen | Acta Crystallogr D Biol Crystallogr | 1999 | 10089316 | Yes |
1346 | 1351 | 1351.0 | 36.51 | 36.5 | Python: a programming language for software integration and development. | M F Sanner | J Mol Graph Model | 1999 | 10660911 | Yes |
1347 | 2702 | 1351.0 | 87.37 | 43.7 | Autophagy: renovation of cells and tissues. | Noboru Mizushima, Masaaki Komatsu | Cell | 2011 | 22078875 | No |
1348 | 1350 | 1350.0 | 81.35 | 81.3 | Brain dopamine receptors. | P Seeman | Pharmacol Rev | 1980 | 6117090 | No |
1349 | 1350 | 1350.0 | 50.62 | 50.6 | Constructions of masculinity and their influence on men's well-being: a theory of gender and health. | W H Courtenay | Soc Sci Med | 2000 | 10741575 | No |
1350 | 1350 | 1350.0 | 24.57 | 24.6 | Cell cycle checkpoint signaling through the ATM and ATR kinases. | R T Abraham | Genes Dev | 2001 | 11544175 | No |
1351 | 2698 | 1349.0 | 80.36 | 40.2 | Protein folding in the cell. | M J Gething, J Sambrook | Nature | 1992 | 1731198 | No |
1352 | 1349 | 1349.0 | 75.78 | 75.8 | Determinants of low birth weight: methodological assessment and meta-analysis. | M S Kramer | Bull World Health Organ | 1987 | 3322602 | No |
1353 | 1349 | 1349.0 | 0.0 | 0.0 | Pedigrees of some mutant strains of Escherichia coli K-12. | B J Bachmann | Bacteriol Rev | 1972 | 4568763 | No |
1354 | 1349 | 1349.0 | 39.35 | 39.4 | From sensation to cognition. | M M Mesulam | Brain | 1998 | 9648540 | No |
1355 | 1347 | 1347.0 | 0.0 | 0.0 | The micronucleus test. | W Schmid | Mutat Res | 1975 | 48190 | Yes |
1356 | 1347 | 1347.0 | 0.0 | 0.0 | Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli. | E M Witkin | Bacteriol Rev | 1976 | 795416 | No |
1357 | 1347 | 1347.0 | 30.33 | 30.3 | Neurotrophins and their receptors: a convergence point for many signalling pathways. | Moses V Chao | Nat Rev Neurosci | 2003 | 12671646 | No |
1358 | 5385 | 1346.2 | 277.73 | 69.4 | jModelTest 2: more models, new heuristics and parallel computing. | Diego Darriba, Guillermo L Taboada, Ramón Doallo, David Posada | Nat Methods | 2012 | 22847109 | Yes |
1359 | 2692 | 1346.0 | 80.47 | 40.2 | Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter. | P J Southern, P Berg | J Mol Appl Genet | 1982 | 6286831 | Yes |
1360 | 1346 | 1346.0 | 27.4 | 27.4 | How cells read TGF-beta signals. | J Massagué | Nat Rev Mol Cell Biol | 2000 | 11252892 | No |
1361 | 1345 | 1345.0 | 70.55 | 70.5 | Interleukin-1. | C A Dinarello | Rev Infect Dis | 1984 | 6369481 | No |
1362 | 4035 | 1345.0 | 124.42 | 41.5 | The metabolic syndrome--a new worldwide definition. | K George M M Alberti, Paul Zimmet, Jonathan Shaw | Lancet | 2005 | 16182882 | Yes |
1363 | 2689 | 1344.5 | 95.04 | 47.5 | Threshold-free cluster enhancement: addressing problems of smoothing, threshold dependence and localisation in cluster inference. | Stephen M Smith, Thomas E Nichols | Neuroimage | 2009 | 18501637 | Yes |
1364 | 13436 | 1343.6 | 526.42 | 52.6 | The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. | F C Arnett, S M Edworthy, D A Bloch, D J McShane, J F Fries, N S Cooper, L A Healey, S R Kaplan, M H Liang, H S Luthra | Arthritis Rheum | 1988 | 3358796 | Yes |
1365 | 1343 | 1343.0 | 0.0 | 0.0 | A modified card sorting test sensitive to frontal lobe defects. | H E Nelson | Cortex | 1976 | 1009768 | Yes |
1366 | 1343 | 1343.0 | 57.81 | 57.8 | A cortical network for directed attention and unilateral neglect. | M M Mesulam | Ann Neurol | 1981 | 7032417 | No |
1367 | 1343 | 1343.0 | 35.37 | 35.4 | Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. | B L Wajchenberg | Endocr Rev | 2000 | 11133069 | No |
1368 | 2684 | 1342.0 | 53.89 | 26.9 | Cellular motility driven by assembly and disassembly of actin filaments. | Thomas D Pollard, Gary G Borisy | Cell | 2003 | 12600310 | No |
1369 | 4025 | 1341.7 | 79.0 | 26.3 | Notch signaling: cell fate control and signal integration in development. | S Artavanis-Tsakonas, M D Rand, R J Lake | Science | 1999 | 10221902 | No |
1370 | 2683 | 1341.5 | 127.33 | 63.7 | The three-factor eating questionnaire to measure dietary restraint, disinhibition and hunger. | A J Stunkard, S Messick | J Psychosom Res | 1985 | 3981480 | Yes |
1371 | 1341 | 1341.0 | 32.14 | 32.1 | An extensively modified version of MolScript that includes greatly enhanced coloring capabilities. | R M Esnouf | J Mol Graph Model | 1997 | 9385560 | Yes |
1372 | 1341 | 1341.0 | 0.0 | 0.0 | POTENTIAL, IMPEDANCE, AND RECTIFICATION IN MEMBRANES. | D E Goldman | J Gen Physiol | 1943 | 19873371 | Yes |
1373 | 1340 | 1340.0 | 53.25 | 53.2 | Intracellular calcium homeostasis. | E Carafoli | Annu Rev Biochem | 1987 | 3304139 | No |
1374 | 1340 | 1340.0 | 0.0 | 0.0 | Methods for the quantitative estimation of N-acetylneuraminic acid and their application to hydrolysates of sialomucoids. | D AMINOFF | Biochem J | 1961 | 13860975 | Yes |
1375 | 2680 | 1340.0 | 69.06 | 34.5 | Shared principles in NF-kappaB signaling. | Matthew S Hayden, Sankar Ghosh | Cell | 2008 | 18267068 | No |
1376 | 2679 | 1339.5 | 57.84 | 28.9 | Fitting a mixture model by expectation maximization to discover motifs in biopolymers. | T L Bailey, C Elkan | Proc Int Conf Intell Syst Mol Biol | 1994 | 7584402 | Yes |
1377 | 4017 | 1339.0 | 92.06 | 30.7 | Efficient selection for high-expression transfectants with a novel eukaryotic vector. | H Niwa, K Yamamura, J Miyazaki | Gene | 1991 | 1660837 | Yes |
1378 | 1339 | 1339.0 | 30.37 | 30.4 | Oxidative stress shortens telomeres. | Thomas von Zglinicki | Trends Biochem Sci | 2002 | 12114022 | Yes |
1379 | 1338 | 1338.0 | 43.69 | 43.7 | Accurate Coulomb-fitting basis sets for H to Rn. | Florian Weigend | Phys Chem Chem Phys | 2006 | 16633586 | Yes |
1380 | 1336 | 1336.0 | 54.07 | 54.1 | Large-scale neurocognitive networks and distributed processing for attention, language, and memory. | M M Mesulam | Ann Neurol | 1990 | 2260847 | No |
1381 | 1336 | 1336.0 | 0.0 | 0.0 | Simple memory: a theory for archicortex. | D Marr | Philos Trans R Soc Lond B Biol Sci | 1971 | 4399412 | Yes |
1382 | 2672 | 1336.0 | 70.27 | 35.1 | A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids. | D Wessel, U I Flügge | Anal Biochem | 1984 | 6731838 | Yes |
1383 | 4008 | 1336.0 | 114.27 | 38.1 | A neural substrate of prediction and reward. | W Schultz, P Dayan, P R Montague | Science | 1997 | 9054347 | No |
1384 | 2672 | 1336.0 | 63.69 | 31.8 | Complex networks orchestrate epithelial-mesenchymal transitions. | Jean Paul Thiery, Jonathan P Sleeman | Nat Rev Mol Cell Biol | 2006 | 16493418 | No |
1385 | 2671 | 1335.5 | 0.0 | 0.0 | A fluorometric method for determination of oxidized and reduced glutathione in tissues. | P J Hissin, R Hilf | Anal Biochem | 1976 | 962076 | Yes |
1386 | 8013 | 1335.5 | 275.86 | 46.0 | Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. | Ronald C Kessler, Patricia Berglund, Olga Demler, Robert Jin, Kathleen R Merikangas, Ellen E Walters | Arch Gen Psychiatry | 2005 | 15939837 | Yes |
1387 | 1334 | 1334.0 | 70.69 | 70.7 | The drug abuse screening test. | H A Skinner | Addict Behav | 1982 | 7183189 | Yes |
1388 | 1334 | 1334.0 | 43.01 | 43.0 | Determination of minimum inhibitory concentrations. | J M Andrews | J Antimicrob Chemother | 2001 | 11420333 | Yes |
1389 | 2667 | 1333.5 | 61.55 | 30.8 | Why do cancers have high aerobic glycolysis? | Robert A Gatenby, Robert J Gillies | Nat Rev Cancer | 2004 | 15516961 | No |
1390 | 1333 | 1333.0 | 37.41 | 37.4 | Structural design and molecular evolution of a cytokine receptor superfamily. | J F Bazan | Proc Natl Acad Sci U S A | 1990 | 2169613 | Yes |
1391 | 1333 | 1333.0 | 49.53 | 49.5 | Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. | Leonardo Pantoni | Lancet Neurol | 2010 | 20610345 | No |
1392 | 2665 | 1332.5 | 204.16 | 102.1 | A clinical method of functional assessment of the shoulder. | C R Constant, A H Murley | Clin Orthop Relat Res | 1987 | 3791738 | Yes |
1393 | 1332 | 1332.0 | 53.69 | 53.7 | Pineal melatonin: cell biology of its synthesis and of its physiological interactions. | R J Reiter | Endocr Rev | 1991 | 1649044 | No |
1394 | 1332 | 1332.0 | 31.63 | 31.6 | An approximately unbiased test of phylogenetic tree selection. | Hidetoshi Shimodaira | Syst Biol | 2002 | 12079646 | Yes |
1395 | 2663 | 1331.5 | 0.0 | 0.0 | Receptive fields and functional architecture of monkey striate cortex. | D H Hubel, T N Wiesel | J Physiol | 1968 | 4966457 | Yes |
1396 | 2661 | 1330.5 | 105.59 | 52.8 | Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. | F Denizot, R Lang | J Immunol Methods | 1986 | 3486233 | Yes |
1397 | 2661 | 1330.5 | 60.68 | 30.3 | Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. | Gary L Johnson, Razvan Lapadat | Science | 2002 | 12471242 | No |
1398 | 1330 | 1330.0 | 33.81 | 33.8 | Mammalian G1 cyclins. | C J Sherr | Cell | 1993 | 8513492 | No |
1399 | 1330 | 1330.0 | 28.44 | 28.4 | Cell cycle checkpoints: preventing an identity crisis. | S J Elledge | Science | 1996 | 8939848 | No |
1400 | 13294 | 1329.4 | 547.15 | 54.7 | Measurement of protein using bicinchoninic acid. | P K Smith, R I Krohn, G T Hermanson, A K Mallia, F H Gartner, M D Provenzano, E K Fujimoto, N M Goeke, B J Olson, D C Klenk | Anal Biochem | 1985 | 3843705 | Yes |
1401 | 1329 | 1329.0 | 42.1 | 42.1 | Leptospirosis. | P N Levett | Clin Microbiol Rev | 2001 | 11292640 | No |
1402 | 2657 | 1328.5 | 131.7 | 65.8 | Assays of glutathione peroxidase. | L Flohé, W A Günzler | Methods Enzymol | 1984 | 6727659 | Yes |
1403 | 2657 | 1328.5 | 58.45 | 29.2 | NF-kappaB regulation in the immune system. | Qiutang Li, Inder M Verma | Nat Rev Immunol | 2002 | 12360211 | No |
1404 | 1328 | 1328.0 | 33.34 | 33.3 | Introduction to NF-kappaB: players, pathways, perspectives. | T D Gilmore | Oncogene | 2006 | 17072321 | No |
1405 | 1326 | 1326.0 | 0.0 | 0.0 | Stereological principles for morphometry in electron microscopic cytology. | E R Weibel | Int Rev Cytol | 1969 | 4899604 | No |
1406 | 2652 | 1326.0 | 56.71 | 28.4 | Missing pieces in the NF-kappaB puzzle. | Sankar Ghosh, Michael Karin | Cell | 2002 | 11983155 | No |
1407 | 1326 | 1326.0 | 31.87 | 31.9 | Perceptions of epigenetics. | Adrian Bird | Nature | 2007 | 17522671 | Yes |
1408 | 5303 | 1325.8 | 168.29 | 42.1 | Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. | B Biswal, F Z Yetkin, V M Haughton, J S Hyde | Magn Reson Med | 1995 | 8524021 | Yes |
1409 | 6624 | 1324.8 | 190.43 | 38.1 | Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. | Alan S Go, Glenn M Chertow, Dongjie Fan, Charles E McCulloch, Chi-yuan Hsu | N Engl J Med | 2004 | 15385656 | Yes |
1410 | 2649 | 1324.5 | 109.0 | 54.5 | Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. | R A DeFronzo, E Ferrannini | Diabetes Care | 1991 | 2044434 | No |
1411 | 1324 | 1324.0 | 43.21 | 43.2 | Trail Making Test A and B: normative data stratified by age and education. | Tom N Tombaugh | Arch Clin Neuropsychol | 2004 | 15010086 | Yes |
1412 | 2647 | 1323.5 | 93.23 | 46.6 | Molecular mechanisms and clinical applications of angiogenesis. | Peter Carmeliet, Rakesh K Jain | Nature | 2011 | 21593862 | No |
1413 | 1323 | 1323.0 | 59.0 | 59.0 | The linear-quadratic formula and progress in fractionated radiotherapy. | J F Fowler | Br J Radiol | 1989 | 2670032 | No |
1414 | 1323 | 1323.0 | 58.69 | 58.7 | Intermediate filaments as mechanical integrators of cellular space. | E Lazarides | Nature | 1980 | 7188712 | Yes |
1415 | 1322 | 1322.0 | 0.0 | 0.0 | Areas, volumes, packing and protein structure. | F M Richards | Annu Rev Biophys Bioeng | 1977 | 326146 | No |
1416 | 1322 | 1322.0 | 72.26 | 72.3 | Adverse health effects of high-effort/low-reward conditions. | J Siegrist | J Occup Health Psychol | 1996 | 9547031 | No |
1417 | 1321 | 1321.0 | 37.72 | 37.7 | Recognition of errors in three-dimensional structures of proteins. | M J Sippl | Proteins | 1993 | 8108378 | Yes |
1418 | 1321 | 1321.0 | 35.43 | 35.4 | A revolution in optical manipulation. | David G Grier | Nature | 2003 | 12917694 | No |
1419 | 1320 | 1320.0 | 0.0 | 0.0 | Some studies of the protein-binding of steroids and their application to the routine micro and ultramicro measurement of various steroids in body fluids by competitive protein-binding radioassay. | B E Murphy | J Clin Endocrinol Metab | 1967 | 4291524 | Yes |
1420 | 1320 | 1320.0 | 0.0 | 0.0 | Molecular weight determination of protein-dodecyl sulfate complexes by gel electrophoresis in a discontinuous buffer system. | D M Neville | J Biol Chem | 1971 | 5127429 | Yes |
1421 | 1320 | 1320.0 | 32.18 | 32.2 | Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. | G L Semenza | Annu Rev Cell Dev Biol | 1999 | 10611972 | No |
1422 | 1320 | 1320.0 | 31.97 | 32.0 | From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels. | W A Catterall | Neuron | 2000 | 10798388 | No |
1423 | 1319 | 1319.0 | 0.0 | 0.0 | The relationship between the spleen colony-forming cell and the haemopoietic stem cell. | R Schofield | Blood Cells | 1978 | 747780 | Yes |
1424 | 1319 | 1319.0 | 37.37 | 37.4 | Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia. | Shitij Kapur | Am J Psychiatry | 2003 | 12505794 | No |
1425 | 2637 | 1318.5 | 72.15 | 36.1 | Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. | Robert Visse, Hideaki Nagase | Circ Res | 2003 | 12730128 | No |
1426 | 1318 | 1318.0 | 39.85 | 39.9 | Task switching. | Stephen Monsell | Trends Cogn Sci | 2003 | 12639695 | Yes |
1427 | 2636 | 1318.0 | 60.85 | 30.4 | Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions. | E Krissinel, K Henrick | Acta Crystallogr D Biol Crystallogr | 2004 | 15572779 | Yes |
1428 | 1317 | 1317.0 | 58.25 | 58.2 | Free radicals, antioxidants, and human disease: curiosity, cause, or consequence? | B Halliwell | Lancet | 1994 | 7915779 | No |
1429 | 2634 | 1317.0 | 0.0 | 0.0 | Determination of the base composition of deoxyribonucleic acid from its thermal denaturation temperature. | J MARMUR, P DOTY | J Mol Biol | 1962 | 14470099 | Yes |
1430 | 1317 | 1317.0 | 27.22 | 27.2 | Protein degradation and protection against misfolded or damaged proteins. | Alfred L Goldberg | Nature | 2003 | 14685250 | No |
1431 | 2632 | 1316.0 | 0.0 | 0.0 | Polymyositis and dermatomyositis (first of two parts). | A Bohan, J B Peter | N Engl J Med | 1975 | 1090839 | No |
1432 | 1316 | 1316.0 | 34.13 | 34.1 | Structural features in eukaryotic mRNAs that modulate the initiation of translation. | M Kozak | J Biol Chem | 1991 | 1939050 | No |
1433 | 1315 | 1315.0 | 38.04 | 38.0 | The corticosteroid receptor hypothesis of depression. | F Holsboer | Neuropsychopharmacology | 2000 | 11027914 | No |
1434 | 5257 | 1314.2 | 144.68 | 36.2 | Improved optimization for the robust and accurate linear registration and motion correction of brain images. | Mark Jenkinson, Peter Bannister, Michael Brady, Stephen Smith | Neuroimage | 2002 | 12377157 | Yes |
1435 | 2628 | 1314.0 | 99.64 | 49.8 | Separate visual pathways for perception and action. | M A Goodale, A D Milner | Trends Neurosci | 1992 | 1374953 | No |
1436 | 3942 | 1314.0 | 151.84 | 50.6 | Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. | H Esterbauer, R J Schaur, H Zollner | Free Radic Biol Med | 1991 | 1937131 | No |
1437 | 3942 | 1314.0 | 104.2 | 34.7 | Click Chemistry: Diverse Chemical Function from a Few Good Reactions. | Hartmuth C. Kolb, M. G. Finn, K. Barry Sharpless | Angew Chem Int Ed Engl | 2001 | 11433435 | Yes |
1438 | 1314 | 1314.0 | 34.57 | 34.6 | Thiazolidinediones. | Hannele Yki-Järvinen | N Engl J Med | 2004 | 15356308 | No |
1439 | 2628 | 1314.0 | 57.98 | 29.0 | Toll-like receptor control of the adaptive immune responses. | Akiko Iwasaki, Ruslan Medzhitov | Nat Immunol | 2004 | 15454922 | No |
1440 | 2627 | 1313.5 | 54.74 | 27.4 | Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. | O Tetsu, F McCormick | Nature | 1999 | 10201372 | Yes |
1441 | 2627 | 1313.5 | 83.39 | 41.7 | The precuneus: a review of its functional anatomy and behavioural correlates. | Andrea E Cavanna, Michael R Trimble | Brain | 2006 | 16399806 | No |
1442 | 1313 | 1313.0 | 42.73 | 42.7 | Oxidative stress: oxidants and antioxidants. | H Sies | Exp Physiol | 1997 | 9129943 | No |
1443 | 2625 | 1312.5 | 104.89 | 52.4 | Shifting the genomic gold standard for the prokaryotic species definition. | Michael Richter, Ramon Rosselló-Móra | Proc Natl Acad Sci U S A | 2009 | 19855009 | Yes |
1444 | 2624 | 1312.0 | 90.68 | 45.3 | Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI. | P J Basser, C Pierpaoli | J Magn Reson B | 1996 | 8661285 | Yes |
1445 | 1312 | 1312.0 | 34.41 | 34.4 | Hypertrophic cardiomyopathy: a systematic review. | Barry J Maron | JAMA | 2002 | 11886323 | No |
1446 | 1312 | 1312.0 | 0.0 | 0.0 | Cerebral vascular accidents in patients over the age of 60. II. Prognosis. | J RANKIN | Scott Med J | 1957 | 13432835 | Yes |
1447 | 1311 | 1311.0 | 51.18 | 51.2 | Health consequences of obesity in youth: childhood predictors of adult disease. | W H Dietz | Pediatrics | 1998 | 12224658 | No |
1448 | 3933 | 1311.0 | 93.71 | 31.2 | An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. | J K Eng, A L McCormack, J R Yates | J Am Soc Mass Spectrom | 1994 | 24226387 | Yes |
1449 | 1309 | 1309.0 | 0.0 | 0.0 | Chromatin structure: a repeating unit of histones and DNA. | R D Kornberg | Science | 1974 | 4825889 | Yes |
1450 | 2618 | 1309.0 | 117.06 | 58.5 | Pain assessment: global use of the Brief Pain Inventory. | C S Cleeland, K M Ryan | Ann Acad Med Singap | 1994 | 8080219 | No |
1451 | 2616 | 1308.0 | 62.91 | 31.5 | Cell migration: a physically integrated molecular process. | D A Lauffenburger, A F Horwitz | Cell | 1996 | 8608589 | No |
1452 | 1308 | 1308.0 | 36.04 | 36.0 | The biology of incretin hormones. | Daniel J Drucker | Cell Metab | 2006 | 16517403 | No |
1453 | 7845 | 1307.5 | 260.95 | 43.5 | Positional cloning of the mouse obese gene and its human homologue. | Y Zhang, R Proenca, M Maffei, M Barone, L Leopold, J M Friedman | Nature | 1994 | 7984236 | Yes |
1454 | 1307 | 1307.0 | 0.0 | 0.0 | Axo-somatic and axo-dendritic synapses of the cerebral cortex: an electron microscope study. | E G GRAY | J Anat | 1959 | 13829103 | Yes |
1455 | 1306 | 1306.0 | 51.34 | 51.3 | Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. | M Zasloff | Proc Natl Acad Sci U S A | 1987 | 3299384 | Yes |
1456 | 1306 | 1306.0 | 26.8 | 26.8 | Germinal centers. | I C MacLennan | Annu Rev Immunol | 1994 | 8011279 | No |
1457 | 3917 | 1305.7 | 140.27 | 46.8 | Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. | P A Wolf, R D Abbott, W B Kannel | Stroke | 1991 | 1866765 | Yes |
1458 | 13051 | 1305.1 | 350.02 | 35.0 | Multilineage potential of adult human mesenchymal stem cells. | M F Pittenger, A M Mackay, S C Beck, R K Jaiswal, R Douglas, J D Mosca, M A Moorman, D W Simonetti, S Craig, D R Marshak | Science | 1999 | 10102814 | Yes |
1459 | 1305 | 1305.0 | 26.09 | 26.1 | Vienna RNA secondary structure server. | Ivo L Hofacker | Nucleic Acids Res | 2003 | 12824340 | Yes |
1460 | 1305 | 1305.0 | 48.36 | 48.4 | Loss, trauma, and human resilience: have we underestimated the human capacity to thrive after extremely aversive events? | George A Bonanno | Am Psychol | 2004 | 14736317 | No |
1461 | 1304 | 1304.0 | 46.73 | 46.7 | Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy. | Y Ben-Ari | Neuroscience | 1985 | 2859548 | No |
1462 | 5210 | 1302.5 | 245.53 | 61.4 | 16S ribosomal DNA amplification for phylogenetic study. | W G Weisburg, S M Barns, D A Pelletier, D J Lane | J Bacteriol | 1991 | 1987160 | Yes |
1463 | 1301 | 1301.0 | 44.63 | 44.6 | Infrared spectroscopy of proteins. | Andreas Barth | Biochim Biophys Acta | 2007 | 17692815 | No |
1464 | 1300 | 1300.0 | 40.56 | 40.6 | Oxidative stress hypothesis in Alzheimer's disease. | W R Markesbery | Free Radic Biol Med | 1997 | 9165306 | No |
1465 | 1300 | 1300.0 | 27.46 | 27.5 | Immunosuppressive networks in the tumour environment and their therapeutic relevance. | Weiping Zou | Nat Rev Cancer | 2005 | 15776005 | No |
1466 | 7799 | 1299.8 | 281.57 | 46.9 | Cancer statistics, 2009. | Ahmedin Jemal, Rebecca Siegel, Elizabeth Ward, Yongping Hao, Jiaquan Xu, Michael J Thun | CA Cancer J Clin | 2009 | 19474385 | Yes |
1467 | 1299 | 1299.0 | 46.46 | 46.5 | Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli. | G C Walker | Microbiol Rev | 1984 | 6371470 | No |
1468 | 1298 | 1298.0 | 33.32 | 33.3 | Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone. | M B Luskin | Neuron | 1993 | 8338665 | Yes |
1469 | 10383 | 1297.9 | 295.34 | 36.9 | Electric field effect in atomically thin carbon films. | K S Novoselov, A K Geim, S V Morozov, D Jiang, Y Zhang, S V Dubonos, I V Grigorieva, A A Firsov | Science | 2004 | 15499015 | Yes |
1470 | 3892 | 1297.3 | 95.69 | 31.9 | Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. | J E Darnell, I M Kerr, G R Stark | Science | 1994 | 8197455 | No |
1471 | 1296 | 1296.0 | 37.73 | 37.7 | Precision mapping of quantitative trait loci. | Z B Zeng | Genetics | 1994 | 8013918 | Yes |
1472 | 1296 | 1296.0 | 27.32 | 27.3 | Intrinsically unstructured proteins. | Peter Tompa | Trends Biochem Sci | 2002 | 12368089 | No |
1473 | 1295 | 1295.0 | 47.91 | 47.9 | The role of the amygdala in fear and anxiety. | M Davis | Annu Rev Neurosci | 1992 | 1575447 | No |
1474 | 1295 | 1295.0 | 43.69 | 43.7 | The complete general secretory pathway in gram-negative bacteria. | A P Pugsley | Microbiol Rev | 1993 | 8096622 | No |
1475 | 1295 | 1295.0 | 33.53 | 33.5 | Pathogenesis of group A streptococcal infections. | M W Cunningham | Clin Microbiol Rev | 2000 | 10885988 | No |
1476 | 2588 | 1294.0 | 73.3 | 36.6 | Empirical threshold values for quantitative trait mapping. | G A Churchill, R W Doerge | Genetics | 1994 | 7851788 | Yes |
1477 | 2588 | 1294.0 | 78.44 | 39.2 | Multiple sclerosis. | Alastair Compston, Alasdair Coles | Lancet | 2008 | 18970977 | Yes |
1478 | 2588 | 1294.0 | 105.02 | 52.5 | Microenvironmental regulation of tumor progression and metastasis. | Daniela F Quail, Johanna A Joyce | Nat Med | 2013 | 24202395 | No |
1479 | 2587 | 1293.5 | 51.9 | 25.9 | The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. | Michael H Glickman, Aaron Ciechanover | Physiol Rev | 2002 | 11917093 | No |
1480 | 1293 | 1293.0 | 0.0 | 0.0 | Selforganization of matter and the evolution of biological macromolecules. | M Eigen | Naturwissenschaften | 1971 | 4942363 | No |
1481 | 1292 | 1292.0 | 32.51 | 32.5 | An analysis of vertebrate mRNA sequences: intimations of translational control. | M Kozak | J Cell Biol | 1991 | 1955461 | No |
1482 | 1292 | 1292.0 | 52.67 | 52.7 | Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage. | D W Choi | Trends Neurosci | 1988 | 2469166 | No |
1483 | 1292 | 1292.0 | 28.24 | 28.2 | Regulatory T cells, tumour immunity and immunotherapy. | Weiping Zou | Nat Rev Immunol | 2006 | 16557261 | No |
1484 | 1292 | 1292.0 | 53.63 | 53.6 | Large-scale brain networks and psychopathology: a unifying triple network model. | Vinod Menon | Trends Cogn Sci | 2011 | 21908230 | No |
1485 | 1291 | 1291.0 | 27.23 | 27.2 | RNA silencing in plants. | David Baulcombe | Nature | 2004 | 15372043 | No |
1486 | 2581 | 1290.5 | 89.37 | 44.7 | Alzheimer's disease. | Henry W Querfurth, Frank M LaFerla | N Engl J Med | 2010 | 20107219 | No |
1487 | 1289 | 1289.0 | 0.0 | 0.0 | Postsynaptic supersensitivity after 6-hydroxy-dopamine induced degeneration of the nigro-striatal dopamine system. | U Ungerstedt | Acta Physiol Scand Suppl | 1971 | 4332693 | Yes |
1488 | 1289 | 1289.0 | 26.99 | 27.0 | Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing. | D I Svergun | Biophys J | 1999 | 10354416 | Yes |
1489 | 1289 | 1289.0 | 0.0 | 0.0 | ENZYMATIC BASIS FOR ACTIVE TRANSPORT OF NA+ AND K+ ACROSS CELL MEMBRANE. | J C SKOU | Physiol Rev | 1965 | 14337569 | No |
1490 | 2577 | 1288.5 | 0.0 | 0.0 | New method for quantitative determination of uronic acids. | N Blumenkrantz, G Asboe-Hansen | Anal Biochem | 1973 | 4269305 | Yes |
1491 | 2577 | 1288.5 | 132.2 | 66.1 | A standardized set of 260 pictures: norms for name agreement, image agreement, familiarity, and visual complexity. | J G Snodgrass, M Vanderwart | J Exp Psychol Hum Learn | 1980 | 7373248 | Yes |
1492 | 2577 | 1288.5 | 74.36 | 37.2 | Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation. | M A Nitsche, W Paulus | J Physiol | 2000 | 10990547 | Yes |
1493 | 1288 | 1288.0 | 35.52 | 35.5 | An economic method for the fluorescent labeling of PCR fragments. | M Schuelke | Nat Biotechnol | 2000 | 10657137 | Yes |
1494 | 1287 | 1287.0 | 0.0 | 0.0 | In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain. | T R Chen | Exp Cell Res | 1977 | 65285 | Yes |
1495 | 1287 | 1287.0 | 0.0 | 0.0 | Complete nucleotide sequence of the Escherichia coli plasmid pBR322. | J G Sutcliffe | Cold Spring Harb Symp Quant Biol | 1979 | 383387 | Yes |
1496 | 5142 | 1285.5 | 229.96 | 57.5 | Reporting results of cancer treatment. | A B Miller, B Hoogstraten, M Staquet, A Winkler | Cancer | 1981 | 7459811 | Yes |
1497 | 2570 | 1285.0 | 59.3 | 29.6 | The Ki-67 protein: from the known and the unknown. | T Scholzen, J Gerdes | J Cell Physiol | 2000 | 10653597 | No |
1498 | 1284 | 1284.0 | 0.0 | 0.0 | Statistical analysis of enzyme kinetic data. | W W Cleland | Methods Enzymol | 1979 | 502857 | Yes |
1499 | 1284 | 1284.0 | 35.12 | 35.1 | The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. | D M Kingsley | Genes Dev | 1994 | 8299934 | No |
1500 | 1284 | 1284.0 | 34.31 | 34.3 | Insulin and insulin-like growth factor signalling in neoplasia. | Michael Pollak | Nat Rev Cancer | 2008 | 19029956 | No |
1501 | 1283 | 1283.0 | 0.0 | 0.0 | THE ESTIMATION OF PEPSIN, TRYPSIN, PAPAIN, AND CATHEPSIN WITH HEMOGLOBIN. | M L Anson | J Gen Physiol | 1938 | 19873094 | Yes |
1502 | 1282 | 1282.0 | 59.14 | 59.1 | Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons. | P Holzer | Pharmacol Rev | 1991 | 1852779 | No |
1503 | 1282 | 1282.0 | 31.33 | 31.3 | Mechanisms of bone metastasis. | G David Roodman | N Engl J Med | 2004 | 15084698 | No |
1504 | 2563 | 1281.5 | 100.49 | 50.2 | Neurocircuitry of addiction. | George F Koob, Nora D Volkow | Neuropsychopharmacology | 2010 | 19710631 | No |
1505 | 1281 | 1281.0 | 34.59 | 34.6 | A cell culture model for T lymphocyte clonal anergy. | R H Schwartz | Science | 1990 | 2113314 | Yes |
1506 | 1281 | 1281.0 | 61.68 | 61.7 | Antibiotics in the aquatic environment--a review--part I. | Klaus Kümmerer | Chemosphere | 2009 | 19185900 | No |
1507 | 5121 | 1280.2 | 120.26 | 30.1 | MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform. | Kazutaka Katoh, Kazuharu Misawa, Kei-ichi Kuma, Takashi Miyata | Nucleic Acids Res | 2002 | 12136088 | Yes |
1508 | 2559 | 1279.5 | 0.0 | 0.0 | Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. | M Mihara, M Uchiyama | Anal Biochem | 1978 | 655387 | Yes |
1509 | 2558 | 1279.0 | 157.52 | 78.8 | Interrater reliability of a modified Ashworth scale of muscle spasticity. | R W Bohannon, M B Smith | Phys Ther | 1987 | 3809245 | Yes |
1510 | 1278 | 1278.0 | 32.95 | 33.0 | Five rules for the evolution of cooperation. | Martin A Nowak | Science | 2006 | 17158317 | No |
1511 | 1277 | 1277.0 | 0.0 | 0.0 | Why genes in pieces? | W Gilbert | Nature | 1978 | 622185 | Yes |
1512 | 5108 | 1277.0 | 166.36 | 41.6 | Comorbidity measures for use with administrative data. | A Elixhauser, C Steiner, D R Harris, R M Coffey | Med Care | 1998 | 9431328 | Yes |
1513 | 2554 | 1277.0 | 58.54 | 29.3 | Coordination of circadian timing in mammals. | Steven M Reppert, David R Weaver | Nature | 2002 | 12198538 | No |
1514 | 1277 | 1277.0 | 28.13 | 28.1 | The Buccaneer software for automated model building. 1. Tracing protein chains. | Kevin Cowtan | Acta Crystallogr D Biol Crystallogr | 2006 | 16929101 | Yes |
1515 | 2552 | 1276.0 | 77.07 | 38.5 | Building better batteries. | M Armand, J-M Tarascon | Nature | 2008 | 18256660 | No |
1516 | 3827 | 1275.7 | 111.53 | 37.2 | The rapid generation of mutation data matrices from protein sequences. | D T Jones, W R Taylor, J M Thornton | Comput Appl Biosci | 1992 | 1633570 | Yes |
1517 | 2551 | 1275.5 | 66.54 | 33.3 | The incidence of congenital heart disease. | Julien I E Hoffman, Samuel Kaplan | J Am Coll Cardiol | 2002 | 12084585 | No |
1518 | 10195 | 1274.4 | 388.03 | 48.5 | Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. | R K Saiki, D H Gelfand, S Stoffel, S J Scharf, R Higuchi, G T Horn, K B Mullis, H A Erlich | Science | 1988 | 2448875 | Yes |
1519 | 2548 | 1274.0 | 111.73 | 55.9 | The transtheoretical model of health behavior change. | J O Prochaska, W F Velicer | Am J Health Promot | 1997 | 10170434 | No |
1520 | 1274 | 1274.0 | 29.69 | 29.7 | Neurotrophins as synaptic modulators. | M M Poo | Nat Rev Neurosci | 2001 | 11253356 | No |
1521 | 1273 | 1273.0 | 0.0 | 0.0 | A simple fluorometric assay for lipoperoxide in blood plasma. | K Yagi | Biochem Med | 1976 | 962904 | Yes |
1522 | 1273 | 1273.0 | 49.37 | 49.4 | A new automated colorimetric method for measuring total oxidant status. | Ozcan Erel | Clin Biochem | 2005 | 16214125 | Yes |
1523 | 1273 | 1273.0 | 31.5 | 31.5 | Far-field optical nanoscopy. | Stefan W Hell | Science | 2007 | 17525330 | No |
1524 | 6363 | 1272.6 | 137.13 | 27.4 | Prospective identification of tumorigenic breast cancer cells. | Muhammad Al-Hajj, Max S Wicha, Adalberto Benito-Hernandez, Sean J Morrison, Michael F Clarke | Proc Natl Acad Sci U S A | 2003 | 12629218 | Yes |
1525 | 5089 | 1272.2 | 150.9 | 37.7 | p53 mutations in human cancers. | M Hollstein, D Sidransky, B Vogelstein, C C Harris | Science | 1991 | 1905840 | No |
1526 | 1272 | 1272.0 | 39.43 | 39.4 | The world health report 2002 - reducing risks, promoting healthy life. | J J Guilbert | Educ Health (Abingdon) | 2003 | 14741909 | Yes |
1527 | 3813 | 1271.0 | 124.58 | 41.5 | Dating of the human-ape splitting by a molecular clock of mitochondrial DNA. | M Hasegawa, H Kishino, T Yano | J Mol Evol | 1985 | 3934395 | Yes |
1528 | 1271 | 1271.0 | 48.52 | 48.5 | Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances. | Joseph J Volpe | Lancet Neurol | 2009 | 19081519 | No |
1529 | 1270 | 1270.0 | 0.0 | 0.0 | Paced auditory serial-addition task: a measure of recovery from concussion. | D M Gronwall | Percept Mot Skills | 1977 | 866038 | Yes |
1530 | 1270 | 1270.0 | 0.0 | 0.0 | R factor transfer in Rhizobium leguminosarum. | J E Beringer | J Gen Microbiol | 1974 | 4612098 | Yes |
1531 | 2540 | 1270.0 | 80.09 | 40.0 | ATHENA, ARTEMIS, HEPHAESTUS: data analysis for X-ray absorption spectroscopy using IFEFFIT. | B Ravel, M Newville | J Synchrotron Radiat | 2005 | 15968136 | Yes |
1532 | 1269 | 1269.0 | 39.02 | 39.0 | Solvent-accessible surfaces of proteins and nucleic acids. | M L Connolly | Science | 1983 | 6879170 | Yes |
1533 | 3807 | 1269.0 | 161.17 | 53.7 | A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. | J R Le Gall, S Lemeshow, F Saulnier | JAMA | 1993 | 8254858 | Yes |
1534 | 2538 | 1269.0 | 69.15 | 34.6 | Adipose tissue as an endocrine organ. | Erin E Kershaw, Jeffrey S Flier | J Clin Endocrinol Metab | 2004 | 15181022 | No |
1535 | 1269 | 1269.0 | 40.87 | 40.9 | n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases. | Philip C Calder | Am J Clin Nutr | 2006 | 16841861 | No |
1536 | 1268 | 1268.0 | 49.43 | 49.4 | Cognitive reserve. | Yaakov Stern | Neuropsychologia | 2009 | 19467352 | No |
1537 | 2534 | 1267.0 | 82.52 | 41.3 | Rapid and sensitive protein similarity searches. | D J Lipman, W R Pearson | Science | 1985 | 2983426 | Yes |
1538 | 2534 | 1267.0 | 81.68 | 40.8 | An information-maximization approach to blind separation and blind deconvolution. | A J Bell, T J Sejnowski | Neural Comput | 1995 | 7584893 | Yes |
1539 | 1267 | 1267.0 | 50.85 | 50.9 | Cellular defenses against damage from reactive oxygen species. | B P Yu | Physiol Rev | 1994 | 8295932 | No |
1540 | 1267 | 1267.0 | 0.0 | 0.0 | Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal. | S COHEN | J Biol Chem | 1962 | 13880319 | Yes |
1541 | 2532 | 1266.0 | 0.0 | 0.0 | Variations in the pattern of pubertal changes in boys. | W A Marshall, J M Tanner | Arch Dis Child | 1970 | 5440182 | Yes |
1542 | 1266 | 1266.0 | 0.0 | 0.0 | Impulses and Physiological States in Theoretical Models of Nerve Membrane. | R Fitzhugh | Biophys J | 1961 | 19431309 | Yes |
1543 | 1265 | 1265.0 | 49.06 | 49.1 | Validation of a decisional conflict scale. | A M O'Connor | Med Decis Making | 1995 | 7898294 | Yes |
1544 | 1265 | 1265.0 | 25.06 | 25.1 | Aggresomes, inclusion bodies and protein aggregation. | R R Kopito | Trends Cell Biol | 2000 | 11121744 | No |
1545 | 1264 | 1264.0 | 64.16 | 64.2 | Local effector functions of capsaicin-sensitive sensory nerve endings: involvement of tachykinins, calcitonin gene-related peptide and other neuropeptides. | P Holzer | Neuroscience | 1988 | 3288903 | No |
1546 | 1264 | 1264.0 | 53.49 | 53.5 | Falls in older people: epidemiology, risk factors and strategies for prevention. | Laurence Z Rubenstein | Age Ageing | 2006 | 16926202 | No |
1547 | 2527 | 1263.5 | 0.0 | 0.0 | Multiple receptors for dopamine. | J W Kebabian, D B Calne | Nature | 1979 | 215920 | No |
1548 | 2526 | 1263.0 | 90.39 | 45.2 | Oxidative stress, glutamate, and neurodegenerative disorders. | J T Coyle, P Puttfarcken | Science | 1993 | 7901908 | No |
1549 | 2526 | 1263.0 | 52.21 | 26.1 | The evolutionary fate and consequences of duplicate genes. | M Lynch, J S Conery | Science | 2000 | 11073452 | No |
1550 | 1262 | 1262.0 | 35.44 | 35.4 | HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy. | J M Coffin | Science | 1995 | 7824947 | Yes |
1551 | 1262 | 1262.0 | 32.95 | 33.0 | Neurovascular regulation in the normal brain and in Alzheimer's disease. | Costantino Iadecola | Nat Rev Neurosci | 2004 | 15100718 | No |
1552 | 1261 | 1261.0 | 36.13 | 36.1 | Pathogen recognition and inflammatory signaling in innate immune defenses. | Trine H Mogensen | Clin Microbiol Rev | 2009 | 19366914 | No |
1553 | 1260 | 1260.0 | 60.13 | 60.1 | Probiotics in man and animals. | R Fuller | J Appl Bacteriol | 1989 | 2666378 | No |
1554 | 1260 | 1260.0 | 33.0 | 33.0 | A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. | D A Gewirtz | Biochem Pharmacol | 1999 | 10075079 | No |
1555 | 1259 | 1259.0 | 0.0 | 0.0 | Fluorescence energy transfer as a spectroscopic ruler. | L Stryer | Annu Rev Biochem | 1978 | 354506 | No |
1556 | 1259 | 1259.0 | 0.0 | 0.0 | Which elements are excited in electrical stimulation of mammalian central nervous system: a review. | J B Ranck | Brain Res | 1975 | 1102064 | No |
1557 | 1259 | 1259.0 | 51.96 | 52.0 | The crisis in antibiotic resistance. | H C Neu | Science | 1992 | 1509257 | No |
1558 | 1259 | 1259.0 | 60.98 | 61.0 | Modeling and variable selection in epidemiologic analysis. | S Greenland | Am J Public Health | 1989 | 2916724 | Yes |
1559 | 1259 | 1259.0 | 38.13 | 38.1 | Binary Agrobacterium vectors for plant transformation. | M Bevan | Nucleic Acids Res | 1984 | 6095209 | Yes |
1560 | 5032 | 1258.0 | 148.06 | 37.0 | Use of T7 RNA polymerase to direct expression of cloned genes. | F W Studier, A H Rosenberg, J J Dunn, J W Dubendorff | Methods Enzymol | 1990 | 2199796 | Yes |
1561 | 2516 | 1258.0 | 61.24 | 30.6 | Neurotrophins: roles in neuronal development and function. | E J Huang, L F Reichardt | Annu Rev Neurosci | 2001 | 11520916 | No |
1562 | 1258 | 1258.0 | 28.06 | 28.1 | Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy. | R K Jain | Nat Med | 2001 | 11533692 | No |
1563 | 1258 | 1258.0 | 33.97 | 34.0 | In vivo near-infrared fluorescence imaging. | John V Frangioni | Curr Opin Chem Biol | 2003 | 14580568 | No |
1564 | 1257 | 1257.0 | 75.13 | 75.1 | Measurement of health state utilities for economic appraisal. | G W Torrance | J Health Econ | 1986 | 10311607 | No |
1565 | 3770 | 1256.7 | 0.0 | 0.0 | Impact of Event Scale: a measure of subjective stress. | M Horowitz, N Wilner, W Alvarez | Psychosom Med | 1979 | 472086 | Yes |
1566 | 2513 | 1256.5 | 102.98 | 51.5 | Palladium-catalyzed ligand-directed C-H functionalization reactions. | Thomas W Lyons, Melanie S Sanford | Chem Rev | 2010 | 20078038 | No |
1567 | 1256 | 1256.0 | 0.0 | 0.0 | Measuring degree of physical dependence to tobacco smoking with reference to individualization of treatment. | K O Fagerström | Addict Behav | 1978 | 735910 | Yes |
1568 | 2508 | 1254.0 | 0.0 | 0.0 | Prediction of the secondary structure of proteins from their amino acid sequence. | P Y Chou, G D Fasman | Adv Enzymol Relat Areas Mol Biol | 1978 | 364941 | No |
1569 | 1254 | 1254.0 | 46.81 | 46.8 | Efficient analysis of experimental observations. | W J Dixon | Annu Rev Pharmacol Toxicol | 1980 | 7387124 | Yes |
1570 | 2508 | 1254.0 | 0.0 | 0.0 | A "DIRECT-COLORING" THIOCHOLINE METHOD FOR CHOLINESTERASES. | M J KARNOVSKY, L ROOTS | J Histochem Cytochem | 1964 | 14187330 | Yes |
1571 | 1253 | 1253.0 | 0.0 | 0.0 | The kinetics of enzyme-catalyzed reactions with two or more substrates or products. I. Nomenclature and rate equations. | W W CLELAND | Biochim Biophys Acta | 1963 | 14021667 | Yes |
1572 | 2505 | 1252.5 | 65.86 | 32.9 | The human plasma proteome: history, character, and diagnostic prospects. | N Leigh Anderson, Norman G Anderson | Mol Cell Proteomics | 2002 | 12488461 | No |
1573 | 1252 | 1252.0 | 23.49 | 23.5 | Histone acetylation and transcriptional regulatory mechanisms. | K Struhl | Genes Dev | 1998 | 9499396 | No |
1574 | 2504 | 1252.0 | 68.73 | 34.4 | Malignant gliomas in adults. | Patrick Y Wen, Santosh Kesari | N Engl J Med | 2008 | 18669428 | No |
1575 | 1252 | 1252.0 | 36.69 | 36.7 | P-LINCS: A Parallel Linear Constraint Solver for Molecular Simulation. | Berk Hess | J Chem Theory Comput | 2008 | 26619985 | Yes |
1576 | 1251 | 1251.0 | 0.0 | 0.0 | The inverse care law. | J T Hart | Lancet | 1971 | 4100731 | Yes |
1577 | 3750 | 1250.0 | 116.32 | 38.8 | The fusiform face area: a module in human extrastriate cortex specialized for face perception. | N Kanwisher, J McDermott, M M Chun | J Neurosci | 1997 | 9151747 | Yes |
1578 | 1250 | 1250.0 | 54.23 | 54.2 | Screening for prostate cancer: U.S. Preventive Services Task Force recommendation statement. | Virginia A Moyer | Ann Intern Med | 2012 | 22801674 | No |
1579 | 3749 | 1249.7 | 90.67 | 30.2 | NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. | S Ghosh, M J May, E B Kopp | Annu Rev Immunol | 1998 | 9597130 | No |
1580 | 1249 | 1249.0 | 33.59 | 33.6 | On finding all suboptimal foldings of an RNA molecule. | M Zuker | Science | 1989 | 2468181 | No |
1581 | 3747 | 1249.0 | 98.56 | 32.9 | Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets. | Claus Lindbjerg Andersen, Jens Ledet Jensen, Torben Falck Ørntoft | Cancer Res | 2004 | 15289330 | Yes |
1582 | 2496 | 1248.0 | 106.62 | 53.3 | Role of free radicals and catalytic metal ions in human disease: an overview. | B Halliwell, J M Gutteridge | Methods Enzymol | 1990 | 2172697 | No |
1583 | 1248 | 1248.0 | 43.33 | 43.3 | The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system function. | R R Llinás | Science | 1988 | 3059497 | No |
1584 | 3737 | 1245.7 | 103.55 | 34.5 | Two-photon laser scanning fluorescence microscopy. | W Denk, J H Strickler, W W Webb | Science | 1990 | 2321027 | Yes |
1585 | 3736 | 1245.3 | 148.08 | 49.4 | Phylogenetic identification and in situ detection of individual microbial cells without cultivation. | R I Amann, W Ludwig, K H Schleifer | Microbiol Rev | 1995 | 7535888 | No |
1586 | 1245 | 1245.0 | 39.15 | 39.1 | Alpha-crystallin can function as a molecular chaperone. | J Horwitz | Proc Natl Acad Sci U S A | 1992 | 1438232 | Yes |
1587 | 1245 | 1245.0 | 51.18 | 51.2 | Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue'). | M N Marsh | Gastroenterology | 1992 | 1727768 | No |
1588 | 1245 | 1245.0 | 29.7 | 29.7 | How eukaryotic transcriptional activators work. | M Ptashne | Nature | 1988 | 3050531 | No |
1589 | 1245 | 1245.0 | 0.0 | 0.0 | Amino acid difference formula to help explain protein evolution. | R Grantham | Science | 1974 | 4843792 | Yes |
1590 | 1245 | 1245.0 | 43.2 | 43.2 | Glycobiology: Toward Understanding the Function of Sugars. | Raymond A. Dwek | Chem Rev | 1996 | 11848770 | Yes |
1591 | 2489 | 1244.5 | 56.33 | 28.2 | The Bcl2 family: regulators of the cellular life-or-death switch. | Suzanne Cory, Jerry M Adams | Nat Rev Cancer | 2002 | 12209154 | No |
1592 | 16174 | 1244.2 | 482.95 | 37.1 | Clustal W and Clustal X version 2.0. | M A Larkin, G Blackshields, N P Brown, R Chenna, P A McGettigan, H McWilliam, F Valentin, I M Wallace, A Wilm, R Lopez, J D Thompson, T J Gibson, D G Higgins | Bioinformatics | 2007 | 17846036 | Yes |
1593 | 1244 | 1244.0 | 54.27 | 54.3 | The case-crossover design: a method for studying transient effects on the risk of acute events. | M Maclure | Am J Epidemiol | 1991 | 1985444 | Yes |
1594 | 2488 | 1244.0 | 73.04 | 36.5 | Quantum dot bioconjugates for ultrasensitive nonisotopic detection. | W C Chan, S Nie | Science | 1998 | 9748158 | Yes |
1595 | 1244 | 1244.0 | 33.48 | 33.5 | NADPH oxidase: an update. | B M Babior | Blood | 1999 | 10029572 | No |
1596 | 1244 | 1244.0 | 36.08 | 36.1 | Stress and hippocampal plasticity. | B S McEwen | Annu Rev Neurosci | 1999 | 10202533 | No |
1597 | 1244 | 1244.0 | 33.1 | 33.1 | Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. | S C Manolagas | Endocr Rev | 2000 | 10782361 | No |
1598 | 1244 | 1244.0 | 35.3 | 35.3 | Use and misuse of the receiver operating characteristic curve in risk prediction. | Nancy R Cook | Circulation | 2007 | 17309939 | Yes |
1599 | 2487 | 1243.5 | 79.18 | 39.6 | Diarrheagenic Escherichia coli. | J P Nataro, J B Kaper | Clin Microbiol Rev | 1998 | 9457432 | No |
1600 | 1243 | 1243.0 | 42.91 | 42.9 | A computational procedure for determining energetically favorable binding sites on biologically important macromolecules. | P J Goodford | J Med Chem | 1985 | 3892003 | Yes |
1601 | 2486 | 1243.0 | 0.0 | 0.0 | The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites. | J Shine, L Dalgarno | Proc Natl Acad Sci U S A | 1974 | 4598299 | Yes |
1602 | 1243 | 1243.0 | 32.76 | 32.8 | Neuronal synchrony: a versatile code for the definition of relations? | W Singer | Neuron | 1999 | 10677026 | No |
1603 | 1242 | 1242.0 | 41.05 | 41.0 | Leishmaniasis: current situation and new perspectives. | P Desjeux | Comp Immunol Microbiol Infect Dis | 2004 | 15225981 | No |
1604 | 1242 | 1242.0 | 39.07 | 39.1 | Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. | Michael F Holick | Am J Clin Nutr | 2004 | 15585788 | No |
1605 | 1241 | 1241.0 | 56.9 | 56.9 | Simple proton spectroscopic imaging. | W T Dixon | Radiology | 1984 | 6089263 | Yes |
1606 | 1241 | 1241.0 | 34.54 | 34.5 | Myeloperoxidase: friend and foe. | Seymour J Klebanoff | J Leukoc Biol | 2005 | 15689384 | No |
1607 | 2481 | 1240.5 | 129.66 | 64.8 | Multiwfn: a multifunctional wavefunction analyzer. | Tian Lu, Feiwu Chen | J Comput Chem | 2012 | 22162017 | Yes |
1608 | 1240 | 1240.0 | 45.48 | 45.5 | El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases and the El Escorial "Clinical limits of amyotrophic lateral sclerosis" workshop contributors. | B R Brooks | J Neurol Sci | 1994 | 7807156 | Yes |
1609 | 1240 | 1240.0 | 0.0 | 0.0 | The influence of some cations on an adenosine triphosphatase from peripheral nerves. | J C SKOU | Biochim Biophys Acta | 1957 | 13412736 | Yes |
1610 | 1239 | 1239.0 | 29.33 | 29.3 | A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. | Dale R Nyholt | Am J Hum Genet | 2004 | 14997420 | Yes |
1611 | 1239 | 1239.0 | 41.83 | 41.8 | Systemic lupus erythematosus. | George C Tsokos | N Engl J Med | 2011 | 22129255 | No |
1612 | 2476 | 1238.0 | 56.42 | 28.2 | Chemokines: a new classification system and their role in immunity. | A Zlotnik, O Yoshie | Immunity | 2000 | 10714678 | No |
1613 | 1238 | 1238.0 | 31.4 | 31.4 | The molecular logic of endocannabinoid signalling. | Daniele Piomelli | Nat Rev Neurosci | 2003 | 14595399 | No |
1614 | 1237 | 1237.0 | 40.22 | 40.2 | The pathophysiology of tumor necrosis factors. | P Vassalli | Annu Rev Immunol | 1992 | 1590993 | No |
1615 | 1237 | 1237.0 | 41.7 | 41.7 | Extended-spectrum beta-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat. | P A Bradford | Clin Microbiol Rev | 2001 | 11585791 | No |
1616 | 1237 | 1237.0 | 29.88 | 29.9 | Tumor metastasis: mechanistic insights and clinical challenges. | Patricia S Steeg | Nat Med | 2006 | 16892035 | No |
1617 | 1237 | 1237.0 | 28.92 | 28.9 | Cancer epigenomics: DNA methylomes and histone-modification maps. | Manel Esteller | Nat Rev Genet | 2007 | 17339880 | No |
1618 | 3710 | 1236.7 | 86.69 | 28.9 | TOR signaling in growth and metabolism. | Stephan Wullschleger, Robbie Loewith, Michael N Hall | Cell | 2006 | 16469695 | No |
1619 | 1236 | 1236.0 | 29.78 | 29.8 | The NCI60 human tumour cell line anticancer drug screen. | Robert H Shoemaker | Nat Rev Cancer | 2006 | 16990858 | No |
1620 | 7414 | 1235.7 | 266.18 | 44.4 | New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. | Stéphane Guindon, Jean-François Dufayard, Vincent Lefort, Maria Anisimova, Wim Hordijk, Olivier Gascuel | Syst Biol | 2010 | 20525638 | Yes |
1621 | 1235 | 1235.0 | 0.0 | 0.0 | Synaptic density in human frontal cortex - developmental changes and effects of aging. | P R Huttenlocher | Brain Res | 1979 | 427544 | Yes |
1622 | 1235 | 1235.0 | 51.04 | 51.0 | Number of people with glaucoma worldwide. | H A Quigley | Br J Ophthalmol | 1996 | 8695555 | No |
1623 | 2470 | 1235.0 | 61.08 | 30.5 | Issues and challenges facing rechargeable lithium batteries. | J M Tarascon, M Armand | Nature | 2001 | 11713543 | Yes |
1624 | 1235 | 1235.0 | 47.48 | 47.5 | Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders. | Berislav V Zlokovic | Nat Rev Neurosci | 2011 | 22048062 | No |
1625 | 1234 | 1234.0 | 34.38 | 34.4 | Flavonoid biosynthesis. A colorful model for genetics, biochemistry, cell biology, and biotechnology. | B Winkel-Shirley | Plant Physiol | 2001 | 11402179 | No |
1626 | 1234 | 1234.0 | 0.0 | 0.0 | Influences of glucose loading and of injected insulin on hepatic glucose output. | R STEELE | Ann N Y Acad Sci | 1959 | 13833973 | Yes |
1627 | 8633 | 1233.3 | 196.12 | 28.0 | Embryonic stem cell lines derived from human blastocysts. | J A Thomson, J Itskovitz-Eldor, S S Shapiro, M A Waknitz, J J Swiergiel, V S Marshall, J M Jones | Science | 1998 | 9804556 | Yes |
1628 | 1233 | 1233.0 | 0.0 | 0.0 | Cumulative dose-response curves. II. Technique for the making of dose-response curves in isolated organs and the evaluation of drug parameters. | J M VAN ROSSUM | Arch Int Pharmacodyn Ther | 1963 | 13996119 | Yes |
1629 | 1233 | 1233.0 | 34.94 | 34.9 | The amygdala modulates the consolidation of memories of emotionally arousing experiences. | James L McGaugh | Annu Rev Neurosci | 2004 | 15217324 | No |
1630 | 4931 | 1232.8 | 316.5 | 79.1 | Prevalence of childhood and adult obesity in the United States, 2011-2012. | Cynthia L Ogden, Margaret D Carroll, Brian K Kit, Katherine M Flegal | JAMA | 2014 | 24570244 | Yes |
1631 | 1232 | 1232.0 | 29.84 | 29.8 | Hematopoietic stem-cell transplantation. | Edward A Copelan | N Engl J Med | 2006 | 16641398 | No |
1632 | 1231 | 1231.0 | 0.0 | 0.0 | The recurrence of intracranial meningiomas after surgical treatment. | D SIMPSON | J Neurol Neurosurg Psychiatry | 1957 | 13406590 | Yes |
1633 | 2461 | 1230.5 | 63.2 | 31.6 | How matrix metalloproteinases regulate cell behavior. | M D Sternlicht, Z Werb | Annu Rev Cell Dev Biol | 2001 | 11687497 | No |
1634 | 7381 | 1230.2 | 334.1 | 55.7 | Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. | L C Green, D A Wagner, J Glogowski, P L Skipper, J S Wishnok, S R Tannenbaum | Anal Biochem | 1982 | 7181105 | Yes |
1635 | 4920 | 1230.0 | 0.0 | 0.0 | Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. | E A Jaffe, R L Nachman, C G Becker, C R Minick | J Clin Invest | 1973 | 4355998 | Yes |
1636 | 1230 | 1230.0 | 64.51 | 64.5 | Cell damage in the brain: a speculative synthesis. | B K Siesjö | J Cereb Blood Flow Metab | 1981 | 6276420 | No |
1637 | 3690 | 1230.0 | 85.86 | 28.6 | Toll-like receptors. | Kiyoshi Takeda, Tsuneyasu Kaisho, Shizuo Akira | Annu Rev Immunol | 2003 | 12524386 | No |
1638 | 4919 | 1229.8 | 289.5 | 72.4 | The Satisfaction With Life Scale. | E Diener, R A Emmons, R J Larsen, S Griffin | J Pers Assess | 1985 | 16367493 | Yes |
1639 | 1229 | 1229.0 | 0.0 | 0.0 | TRANSFORMATION OF BIOCHEMICALLY DEFICIENT STRAINS OF BACILLUS SUBTILIS BY DEOXYRIBONUCLEATE. | J Spizizen | Proc Natl Acad Sci U S A | 1958 | 16590310 | Yes |
1640 | 2457 | 1228.5 | 54.55 | 27.3 | Development by self-digestion: molecular mechanisms and biological functions of autophagy. | Beth Levine, Daniel J Klionsky | Dev Cell | 2004 | 15068787 | No |
1641 | 1228 | 1228.0 | 28.62 | 28.6 | Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. | S S Ferguson | Pharmacol Rev | 2001 | 11171937 | No |
1642 | 1228 | 1228.0 | 35.4 | 35.4 | Integration, scaling, space-group assignment and post-refinement. | Wolfgang Kabsch | Acta Crystallogr D Biol Crystallogr | 2010 | 20124693 | Yes |
1643 | 2455 | 1227.5 | 81.93 | 41.0 | Mechanisms of salinity tolerance. | Rana Munns, Mark Tester | Annu Rev Plant Biol | 2008 | 18444910 | No |
1644 | 2454 | 1227.0 | 117.36 | 58.7 | The mini-mental state examination: a comprehensive review. | T N Tombaugh, N J McIntyre | J Am Geriatr Soc | 1992 | 1512391 | No |
1645 | 1226 | 1226.0 | 32.86 | 32.9 | Origin, biogenesis, and activity of plant microRNAs. | Olivier Voinnet | Cell | 2009 | 19239888 | No |
1646 | 2451 | 1225.5 | 66.86 | 33.4 | Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. | F Q Schafer, G R Buettner | Free Radic Biol Med | 2001 | 11368918 | No |
1647 | 2451 | 1225.5 | 62.2 | 31.1 | Lipopolysaccharide endotoxins. | Christian R H Raetz, Chris Whitfield | Annu Rev Biochem | 2002 | 12045108 | No |
1648 | 1224 | 1224.0 | 42.68 | 42.7 | Interleukin-6: an overview. | J Van Snick | Annu Rev Immunol | 1990 | 2188664 | No |
1649 | 4894 | 1223.5 | 174.98 | 43.7 | The validity of the Hospital Anxiety and Depression Scale. An updated literature review. | Ingvar Bjelland, Alv A Dahl, Tone Tangen Haug, Dag Neckelmann | J Psychosom Res | 2002 | 11832252 | No |
1650 | 1223 | 1223.0 | 0.0 | 0.0 | Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. | C A Barnes | J Comp Physiol Psychol | 1979 | 221551 | Yes |
1651 | 2446 | 1223.0 | 58.3 | 29.1 | Cancer metastasis: building a framework. | Gaorav P Gupta, Joan Massagué | Cell | 2006 | 17110329 | No |
1652 | 2445 | 1222.5 | 81.35 | 40.7 | Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research. | Sally S Dickerson, Margaret E Kemeny | Psychol Bull | 2004 | 15122924 | Yes |
1653 | 1222 | 1222.0 | 0.0 | 0.0 | METHOD FOR ASSAY OF INTESTINAL DISACCHARIDASES. | A DAHLQVIST | Anal Biochem | 1964 | 14106916 | Yes |
1654 | 2443 | 1221.5 | 66.11 | 33.1 | Unravelling the pathogenesis of inflammatory bowel disease. | R J Xavier, D K Podolsky | Nature | 2007 | 17653185 | No |
1655 | 1221 | 1221.0 | 80.61 | 80.6 | Muscle and tendon: properties, models, scaling, and application to biomechanics and motor control. | F E Zajac | Crit Rev Biomed Eng | 1989 | 2676342 | No |
1656 | 2442 | 1221.0 | 52.78 | 26.4 | Mutations affecting segment number and polarity in Drosophila. | C Nüsslein-Volhard, E Wieschaus | Nature | 1980 | 6776413 | Yes |
1657 | 1221 | 1221.0 | 33.37 | 33.4 | The proto-oncogene Bcl-2 and its role in regulating apoptosis. | G Kroemer | Nat Med | 1997 | 9176486 | No |
1658 | 2438 | 1219.0 | 92.92 | 46.5 | Unified approach for molecular dynamics and density-functional theory. | Car, Parrinello | Phys Rev Lett | 1985 | 10032153 | Yes |
1659 | 2437 | 1218.5 | 83.1 | 41.5 | EQ-5D: a measure of health status from the EuroQol Group. | R Rabin, F de Charro | Ann Med | 2001 | 11491192 | No |
1660 | 2436 | 1218.0 | 66.03 | 33.0 | Steatohepatitis: a tale of two "hits"? | C P Day, O F James | Gastroenterology | 1998 | 9547102 | No |
1661 | 1215 | 1215.0 | 61.8 | 61.8 | The emerging role of lncRNAs in cancer. | Maite Huarte | Nat Med | 2015 | 26540387 | No |
1662 | 3643 | 1214.3 | 137.09 | 45.7 | Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration. | Helga Thorvaldsdóttir, James T Robinson, Jill P Mesirov | Brief Bioinform | 2013 | 22517427 | Yes |
1663 | 1214 | 1214.0 | 0.0 | 0.0 | Stability of proteins: small globular proteins. | P L Privalov | Adv Protein Chem | 1979 | 44431 | No |
1664 | 1214 | 1214.0 | 61.85 | 61.9 | Responses to depression and their effects on the duration of depressive episodes. | S Nolen-Hoeksema | J Abnorm Psychol | 1991 | 1757671 | No |
1665 | 1214 | 1214.0 | 0.0 | 0.0 | The genetical evolution of social behaviour. II. | W D Hamilton | J Theor Biol | 1964 | 5875340 | Yes |
1666 | 1214 | 1214.0 | 30.82 | 30.8 | Neurotrophin-regulated signalling pathways. | Louis F Reichardt | Philos Trans R Soc Lond B Biol Sci | 2006 | 16939974 | No |
1667 | 1214 | 1214.0 | 33.33 | 33.3 | The failing heart--an engine out of fuel. | Stefan Neubauer | N Engl J Med | 2007 | 17360992 | No |
1668 | 1213 | 1213.0 | 36.98 | 37.0 | Molecular biology of prion diseases. | S B Prusiner | Science | 1991 | 1675487 | No |
1669 | 4852 | 1213.0 | 248.84 | 62.2 | An inventory for measuring clinical anxiety: psychometric properties. | A T Beck, N Epstein, G Brown, R A Steer | J Consult Clin Psychol | 1988 | 3204199 | Yes |
1670 | 1212 | 1212.0 | 47.11 | 47.1 | Extracellular ATP: effects, sources and fate. | J L Gordon | Biochem J | 1986 | 3006665 | No |
1671 | 2423 | 1211.5 | 87.42 | 43.7 | From best evidence to best practice: effective implementation of change in patients' care. | Richard Grol, Jeremy Grimshaw | Lancet | 2003 | 14568747 | No |
1672 | 1211 | 1211.0 | 27.76 | 27.8 | The ubiquitin-proteasome proteolytic pathway. | A Ciechanover | Cell | 1994 | 7923371 | No |
1673 | 2421 | 1210.5 | 102.5 | 51.2 | Reactive oxygen species and antioxidant machinery in abiotic stress tolerance in crop plants. | Sarvajeet Singh Gill, Narendra Tuteja | Plant Physiol Biochem | 2010 | 20870416 | No |
1674 | 4841 | 1210.2 | 134.34 | 33.6 | Most mammalian mRNAs are conserved targets of microRNAs. | Robin C Friedman, Kyle Kai-How Farh, Christopher B Burge, David P Bartel | Genome Res | 2009 | 18955434 | Yes |
1675 | 3628 | 1209.3 | 96.12 | 32.0 | Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. | Daniel Falush, Matthew Stephens, Jonathan K Pritchard | Genetics | 2003 | 12930761 | Yes |
1676 | 3628 | 1209.3 | 114.98 | 38.3 | Optimization by simulated annealing. | S Kirkpatrick, C D Gelatt, M P Vecchi | Science | 1983 | 17813860 | Yes |
1677 | 2417 | 1208.5 | 0.0 | 0.0 | A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms. | J A Horne, O Ostberg | Int J Chronobiol | 1976 | 1027738 | Yes |
1678 | 2417 | 1208.5 | 61.66 | 30.8 | A comparison of bayesian methods for haplotype reconstruction from population genotype data. | Matthew Stephens, Peter Donnelly | Am J Hum Genet | 2003 | 14574645 | Yes |
1679 | 1208 | 1208.0 | 0.0 | 0.0 | Disconnexion syndromes in animals and man. I. | N Geschwind | Brain | 1965 | 5318481 | No |
1680 | 1208 | 1208.0 | 35.7 | 35.7 | External validity of randomised controlled trials: "to whom do the results of this trial apply?". | Peter M Rothwell | Lancet | 2005 | 15639683 | Yes |
1681 | 4832 | 1208.0 | 130.52 | 32.6 | The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling. | Konstantin Arnold, Lorenza Bordoli, Jürgen Kopp, Torsten Schwede | Bioinformatics | 2006 | 16301204 | Yes |
1682 | 1207 | 1207.0 | 46.11 | 46.1 | Evidence for a central component of post-injury pain hypersensitivity. | C J Woolf | Nature | 1983 | 6656869 | Yes |
1683 | 2414 | 1207.0 | 78.32 | 39.2 | Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. | B R Celli, W MacNee | Eur Respir J | 2004 | 15219010 | No |
1684 | 2413 | 1206.5 | 0.0 | 0.0 | The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat. | J O'Keefe, J Dostrovsky | Brain Res | 1971 | 5124915 | Yes |
1685 | 1206 | 1206.0 | 0.0 | 0.0 | Determination of free amino groups in proteins by trinitrobenzenesulfonic acid. | A F Habeeb | Anal Biochem | 1966 | 4161471 | Yes |
1686 | 1206 | 1206.0 | 74.81 | 74.8 | The structure and properties of the sense of coherence scale. | A Antonovsky | Soc Sci Med | 1993 | 8480217 | Yes |
1687 | 2410 | 1205.0 | 88.48 | 44.2 | Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltons. | M Karas, F Hillenkamp | Anal Chem | 1988 | 3239801 | Yes |
1688 | 1205 | 1205.0 | 0.0 | 0.0 | The smooth muscle cell. II. Growth of smooth muscle in culture and formation of elastic fibers. | R Ross | J Cell Biol | 1971 | 4327464 | Yes |
1689 | 1205 | 1205.0 | 43.96 | 44.0 | Gold-catalyzed organic reactions. | A Stephen K Hashmi | Chem Rev | 2007 | 17580975 | Yes |
1690 | 2410 | 1205.0 | 93.64 | 46.8 | Saliency, switching, attention and control: a network model of insula function. | Vinod Menon, Lucina Q Uddin | Brain Struct Funct | 2010 | 20512370 | No |
1691 | 1205 | 1205.0 | 66.98 | 67.0 | Statistics corner: A guide to appropriate use of correlation coefficient in medical research. | M M Mukaka | Malawi Med J | 2012 | 23638278 | Yes |
1692 | 1204 | 1204.0 | 40.75 | 40.8 | DNA topoisomerases. | J C Wang | Annu Rev Biochem | 1985 | 2992360 | No |
1693 | 1204 | 1204.0 | 49.75 | 49.8 | Stereology of arbitrary particles. A review of unbiased number and size estimators and the presentation of some new ones, in memory of William R. Thompson. | H J Gundersen | J Microsc | 1986 | 3761363 | Yes |
1694 | 2408 | 1204.0 | 0.0 | 0.0 | Photoperoxidation in isolated chloroplasts. I. Kinetics and stoichiometry of fatty acid peroxidation. | R L Heath, L Packer | Arch Biochem Biophys | 1968 | 5655425 | Yes |
1695 | 1204 | 1204.0 | 24.09 | 24.1 | Ubiquitin-dependent protein degradation. | M Hochstrasser | Annu Rev Genet | 1996 | 8982460 | No |
1696 | 1204 | 1204.0 | 23.02 | 23.0 | The DNA methyltransferases of mammals. | T H Bestor | Hum Mol Genet | 2000 | 11005794 | No |
1697 | 3609 | 1203.0 | 101.99 | 34.0 | Cortical surface-based analysis. II: Inflation, flattening, and a surface-based coordinate system. | B Fischl, M I Sereno, A M Dale | Neuroimage | 1999 | 9931269 | Yes |
1698 | 2404 | 1202.0 | 80.44 | 40.2 | A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes. | S Tabor, C C Richardson | Proc Natl Acad Sci U S A | 1985 | 3156376 | Yes |
1699 | 4805 | 1201.2 | 131.43 | 32.9 | Improved prediction of signal peptides: SignalP 3.0. | Jannick Dyrløv Bendtsen, Henrik Nielsen, Gunnar von Heijne, Søren Brunak | J Mol Biol | 2004 | 15223320 | Yes |
1700 | 2401 | 1200.5 | 69.44 | 34.7 | Obesity. | David W Haslam, W Philip T James | Lancet | 2005 | 16198769 | No |
1701 | 1200 | 1200.0 | 0.0 | 0.0 | Ionic blockage of sodium channels in nerve. | A M Woodhull | J Gen Physiol | 1973 | 4541078 | Yes |
1702 | 2399 | 1199.5 | 63.52 | 31.8 | A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. | L Buck, R Axel | Cell | 1991 | 1840504 | Yes |
1703 | 2399 | 1199.5 | 60.58 | 30.3 | Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. | T Miyashita, J C Reed | Cell | 1995 | 7834749 | Yes |
1704 | 1199 | 1199.0 | 44.96 | 45.0 | The biology of interleukin-6. | T Kishimoto | Blood | 1989 | 2473791 | No |
1705 | 1199 | 1199.0 | 24.64 | 24.6 | Epithelial-mesenchymal transitions in development and pathologies. | Jean Paul Thiery | Curr Opin Cell Biol | 2003 | 14644200 | No |
1706 | 1199 | 1199.0 | 42.72 | 42.7 | Stress signalling pathways that impair prefrontal cortex structure and function. | Amy F T Arnsten | Nat Rev Neurosci | 2009 | 19455173 | No |
1707 | 5994 | 1198.8 | 0.0 | 0.0 | STUDIES OF ILLNESS IN THE AGED. THE INDEX OF ADL: A STANDARDIZED MEASURE OF BIOLOGICAL AND PSYCHOSOCIAL FUNCTION. | S KATZ, A B FORD, R W MOSKOWITZ, B A JACKSON, M W JAFFE | JAMA | 1963 | 14044222 | Yes |
1708 | 2395 | 1197.5 | 120.76 | 60.4 | Avoiding false positives with PCR. | S Kwok, R Higuchi | Nature | 1989 | 2716852 | Yes |
1709 | 5987 | 1197.4 | 281.79 | 56.4 | UCHIME improves sensitivity and speed of chimera detection. | Robert C Edgar, Brian J Haas, Jose C Clemente, Christopher Quince, Rob Knight | Bioinformatics | 2011 | 21700674 | Yes |
1710 | 1197 | 1197.0 | 50.22 | 50.2 | Dual-task interference in simple tasks: data and theory. | H Pashler | Psychol Bull | 1994 | 7972591 | No |
1711 | 4786 | 1196.5 | 0.0 | 0.0 | A rating scale for mania: reliability, validity and sensitivity. | R C Young, J T Biggs, V E Ziegler, D A Meyer | Br J Psychiatry | 1978 | 728692 | Yes |
1712 | 2393 | 1196.5 | 77.41 | 38.7 | miRBase: integrating microRNA annotation and deep-sequencing data. | Ana Kozomara, Sam Griffiths-Jones | Nucleic Acids Res | 2011 | 21037258 | Yes |
1713 | 2392 | 1196.0 | 53.0 | 26.5 | Intrinsically unstructured proteins and their functions. | H Jane Dyson, Peter E Wright | Nat Rev Mol Cell Biol | 2005 | 15738986 | No |
1714 | 1195 | 1195.0 | 31.33 | 31.3 | Molecular basis of long-term plasticity underlying addiction. | E J Nestler | Nat Rev Neurosci | 2001 | 11252991 | No |
1715 | 2389 | 1194.5 | 90.39 | 45.2 | Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. | G R Gibson, M B Roberfroid | J Nutr | 1995 | 7782892 | No |
1716 | 2388 | 1194.0 | 87.16 | 43.6 | Prediction of protein antigenic determinants from amino acid sequences. | T P Hopp, K R Woods | Proc Natl Acad Sci U S A | 1981 | 6167991 | Yes |
1717 | 1194 | 1194.0 | 74.61 | 74.6 | Chronic illness as biographical disruption. | M Bury | Sociol Health Illn | 1982 | 10260456 | Yes |
1718 | 1194 | 1194.0 | 32.75 | 32.8 | Oxidative stress in Parkinson's disease. | Peter Jenner | Ann Neurol | 2003 | 12666096 | No |
1719 | 2384 | 1192.0 | 116.7 | 58.4 | Assessment of eating disorders: interview or self-report questionnaire? | C G Fairburn, S J Beglin | Int J Eat Disord | 1994 | 7866415 | Yes |
1720 | 2384 | 1192.0 | 109.59 | 54.8 | Regulation of microRNA biogenesis. | Minju Ha, V Narry Kim | Nat Rev Mol Cell Biol | 2014 | 25027649 | No |
1721 | 1191 | 1191.0 | 25.77 | 25.8 | Altering the genome by homologous recombination. | M R Capecchi | Science | 1989 | 2660260 | No |
1722 | 1191 | 1191.0 | 31.93 | 31.9 | The mitochondrial permeability transition pore and its role in cell death. | M Crompton | Biochem J | 1999 | 10393078 | No |
1723 | 1191 | 1191.0 | 26.75 | 26.8 | Stability and flexibility of epigenetic gene regulation in mammalian development. | Wolf Reik | Nature | 2007 | 17522676 | No |
1724 | 7144 | 1190.7 | 204.12 | 34.0 | Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. | D J Slamon, G M Clark, S G Wong, W J Levin, A Ullrich, W L McGuire | Science | 1987 | 3798106 | Yes |
1725 | 1190 | 1190.0 | 28.13 | 28.1 | Critical period plasticity in local cortical circuits. | Takao K Hensch | Nat Rev Neurosci | 2005 | 16261181 | No |
1726 | 2378 | 1189.0 | 95.47 | 47.7 | The efficiency of systematic sampling in stereology and its prediction. | H J Gundersen, E B Jensen | J Microsc | 1987 | 3430576 | Yes |
1727 | 1189 | 1189.0 | 47.0 | 47.0 | Polycystic ovary syndrome. | S Franks | N Engl J Med | 1995 | 7651477 | No |
1728 | 3567 | 1189.0 | 109.52 | 36.5 | TCS: a computer program to estimate gene genealogies. | M Clement, D Posada, K A Crandall | Mol Ecol | 2000 | 11050560 | Yes |
1729 | 1189 | 1189.0 | 44.85 | 44.9 | Social relationships and health. | Sheldon Cohen | Am Psychol | 2004 | 15554821 | No |
1730 | 1188 | 1188.0 | 66.99 | 67.0 | The contribution of low birth weight to infant mortality and childhood morbidity. | M C McCormick | N Engl J Med | 1985 | 3880598 | No |
1731 | 2376 | 1188.0 | 56.99 | 28.5 | Microtubules as a target for anticancer drugs. | Mary Ann Jordan, Leslie Wilson | Nat Rev Cancer | 2004 | 15057285 | No |
1732 | 2376 | 1188.0 | 50.08 | 25.0 | Cancer genes and the pathways they control. | Bert Vogelstein, Kenneth W Kinzler | Nat Med | 2004 | 15286780 | No |
1733 | 3564 | 1188.0 | 130.07 | 43.4 | Estimating the mean and variance from the median, range, and the size of a sample. | Stela Pudar Hozo, Benjamin Djulbegovic, Iztok Hozo | BMC Med Res Methodol | 2005 | 15840177 | Yes |
1734 | 1188 | 1188.0 | 60.23 | 60.2 | Pro-resolving lipid mediators are leads for resolution physiology. | Charles N Serhan | Nature | 2014 | 24899309 | No |
1735 | 2375 | 1187.5 | 59.23 | 29.6 | NF-kappaB: a key role in inflammatory diseases. | P P Tak, G S Firestein | J Clin Invest | 2001 | 11134171 | No |
1736 | 1187 | 1187.0 | 46.06 | 46.1 | The atom economy--a search for synthetic efficiency. | B M Trost | Science | 1991 | 1962206 | Yes |
1737 | 1187 | 1187.0 | 0.0 | 0.0 | Dynamic properties of mammalian skeletal muscles. | R I Close | Physiol Rev | 1972 | 4256989 | No |
1738 | 1187 | 1187.0 | 0.0 | 0.0 | Interhemispheric differences in the localization of psychological processes in man. | B Milner | Br Med Bull | 1971 | 4937273 | No |
1739 | 1187 | 1187.0 | 31.75 | 31.8 | PPAR-gamma: adipogenic regulator and thiazolidinedione receptor. | B M Spiegelman | Diabetes | 1998 | 9568680 | No |
1740 | 1187 | 1187.0 | 22.79 | 22.8 | Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy. | M G Gustafsson | J Microsc | 2000 | 10810003 | Yes |
1741 | 1186 | 1186.0 | 38.38 | 38.4 | Trophic factors and neuronal survival. | Y A Barde | Neuron | 1989 | 2697237 | No |
1742 | 1186 | 1186.0 | 0.0 | 0.0 | Cognitive maps in rats and men. | E C TOLMAN | Psychol Rev | 1948 | 18870876 | Yes |
1743 | 1185 | 1185.0 | 39.03 | 39.0 | A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE Task Force on Classification and Terminology. | J Engel | Epilepsia | 2001 | 11422340 | Yes |
1744 | 1185 | 1185.0 | 22.81 | 22.8 | Chromatin modification and epigenetic reprogramming in mammalian development. | En Li | Nat Rev Genet | 2002 | 12209141 | No |
1745 | 1185 | 1185.0 | 0.0 | 0.0 | Discharge patterns and functional organization of mammalian retina. | S W KUFFLER | J Neurophysiol | 1953 | 13035466 | Yes |
1746 | 4739 | 1184.8 | 0.0 | 0.0 | The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. | S P Baker, B O'Neill, W Haddon, W B Long | J Trauma | 1974 | 4814394 | Yes |
1747 | 1184 | 1184.0 | 39.82 | 39.8 | Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms. | J A Beavo | Physiol Rev | 1995 | 7480160 | No |
1748 | 2367 | 1183.5 | 50.12 | 25.1 | Wnt signalling in stem cells and cancer. | Tannishtha Reya, Hans Clevers | Nature | 2005 | 15829953 | No |
1749 | 1183 | 1183.0 | 21.82 | 21.8 | Protein modification by SUMO. | Erica S Johnson | Annu Rev Biochem | 2004 | 15189146 | No |
1750 | 1183 | 1183.0 | 46.66 | 46.7 | The polyvagal perspective. | Stephen W Porges | Biol Psychol | 2007 | 17049418 | No |
1751 | 2365 | 1182.5 | 60.47 | 30.2 | The pathophysiology and treatment of sepsis. | Richard S Hotchkiss, Irene E Karl | N Engl J Med | 2003 | 12519925 | No |
1752 | 1182 | 1182.0 | 32.34 | 32.3 | The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. | H Maeda | Adv Enzyme Regul | 2001 | 11384745 | No |
1753 | 5908 | 1181.6 | 157.32 | 31.5 | Site-directed mutagenesis by overlap extension using the polymerase chain reaction. | S N Ho, H D Hunt, R M Horton, J K Pullen, L R Pease | Gene | 1989 | 2744487 | Yes |
1754 | 2362 | 1181.0 | 73.64 | 36.8 | Early identification of refractory epilepsy. | P Kwan, M J Brodie | N Engl J Med | 2000 | 10660394 | Yes |
1755 | 2361 | 1180.5 | 0.0 | 0.0 | Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans. | D H Figurski, D R Helinski | Proc Natl Acad Sci U S A | 1979 | 377280 | Yes |
1756 | 5902 | 1180.4 | 160.11 | 32.0 | Development and testing of a general amber force field. | Junmei Wang, Romain M Wolf, James W Caldwell, Peter A Kollman, David A Case | J Comput Chem | 2004 | 15116359 | Yes |
1757 | 2360 | 1180.0 | 74.47 | 37.2 | Lipid rafts as a membrane-organizing principle. | Daniel Lingwood, Kai Simons | Science | 2010 | 20044567 | No |
1758 | 2359 | 1179.5 | 57.27 | 28.6 | Inhibitors of mammalian G1 cyclin-dependent kinases. | C J Sherr, J M Roberts | Genes Dev | 1995 | 7758941 | No |
1759 | 3537 | 1179.0 | 0.0 | 0.0 | Research diagnostic criteria: rationale and reliability. | R L Spitzer, J Endicott, E Robins | Arch Gen Psychiatry | 1978 | 655775 | Yes |
1760 | 1179 | 1179.0 | 42.6 | 42.6 | Variations in patients' adherence to medical recommendations: a quantitative review of 50 years of research. | M Robin DiMatteo | Med Care | 2004 | 15076819 | Yes |
1761 | 1178 | 1178.0 | 42.32 | 42.3 | Ionic dependence of glutamate neurotoxicity. | D W Choi | J Neurosci | 1987 | 2880938 | Yes |
1762 | 3532 | 1177.3 | 105.91 | 35.3 | Cognitive and emotional influences in anterior cingulate cortex. | Bush, Luu, Posner | Trends Cogn Sci | 2000 | 10827444 | Yes |
1763 | 1177 | 1177.0 | 25.23 | 25.2 | Macromolecular crowding: obvious but underappreciated. | R J Ellis | Trends Biochem Sci | 2001 | 11590012 | No |
1764 | 2352 | 1176.0 | 86.0 | 43.0 | A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments. | J Messing, J Vieira | Gene | 1982 | 6295880 | Yes |
1765 | 1176 | 1176.0 | 46.82 | 46.8 | A Social Neuroscience Perspective on Adolescent Risk-Taking. | Laurence Steinberg | Dev Rev | 2008 | 18509515 | Yes |
1766 | 1175 | 1175.0 | 40.87 | 40.9 | DNA topoisomerase poisons as antitumor drugs. | L F Liu | Annu Rev Biochem | 1989 | 2549853 | No |
1767 | 2350 | 1175.0 | 90.74 | 45.4 | A rapid boiling method for the preparation of bacterial plasmids. | D S Holmes, M Quigley | Anal Biochem | 1981 | 6269464 | Yes |
1768 | 10573 | 1174.8 | 384.04 | 42.7 | The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. | D V Sheehan, Y Lecrubier, K H Sheehan, P Amorim, J Janavs, E Weiller, T Hergueta, R Baker, G C Dunbar | J Clin Psychiatry | 1998 | 9881538 | No |
1769 | 3524 | 1174.7 | 86.32 | 28.8 | Osteoclast differentiation and activation. | William J Boyle, W Scott Simonet, David L Lacey | Nature | 2003 | 12748652 | No |
1770 | 2349 | 1174.5 | 78.16 | 39.1 | Protective and pathogenic functions of macrophage subsets. | Peter J Murray, Thomas A Wynn | Nat Rev Immunol | 2011 | 21997792 | No |
1771 | 4696 | 1174.0 | 113.75 | 28.4 | Probability-based protein identification by searching sequence databases using mass spectrometry data. | D N Perkins, D J Pappin, D M Creasy, J S Cottrell | Electrophoresis | 1999 | 10612281 | Yes |
1772 | 2348 | 1174.0 | 65.47 | 32.7 | Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. | H Cai, D G Harrison | Circ Res | 2000 | 11073878 | No |
1773 | 1173 | 1173.0 | 46.98 | 47.0 | History of the Rochester Epidemiology Project. | L J Melton | Mayo Clin Proc | 1996 | 8594285 | No |
1774 | 2346 | 1173.0 | 67.65 | 33.8 | The biology of vascular endothelial growth factor. | N Ferrara, T Davis-Smyth | Endocr Rev | 1997 | 9034784 | No |
1775 | 2346 | 1173.0 | 66.84 | 33.4 | Macrophage diversity enhances tumor progression and metastasis. | Bin-Zhi Qian, Jeffrey W Pollard | Cell | 2010 | 20371344 | No |
1776 | 2344 | 1172.0 | 171.0 | 85.5 | Rating systems in the evaluation of knee ligament injuries. | Y Tegner, J Lysholm | Clin Orthop Relat Res | 1985 | 4028566 | Yes |
1777 | 1172 | 1172.0 | 27.51 | 27.5 | DNA in a material world. | Nadrian C Seeman | Nature | 2003 | 12540916 | No |
1778 | 1172 | 1172.0 | 40.19 | 40.2 | Surface plasmon resonance sensors for detection of chemical and biological species. | Jirí Homola | Chem Rev | 2008 | 18229953 | No |
1779 | 1171 | 1171.0 | 45.02 | 45.0 | Gene flow and the geographic structure of natural populations. | M Slatkin | Science | 1987 | 3576198 | Yes |
1780 | 1171 | 1171.0 | 32.47 | 32.5 | A molecular view of microbial diversity and the biosphere. | N R Pace | Science | 1997 | 9115194 | No |
1781 | 1171 | 1171.0 | 0.0 | 0.0 | Structural considerations in the interaction of DNA and acridines. | L S LERMAN | J Mol Biol | 1961 | 13761054 | Yes |
1782 | 1170 | 1170.0 | 0.0 | 0.0 | ATPase activity of myosin correlated with speed of muscle shortening. | M Bárány | J Gen Physiol | 1967 | 4227924 | Yes |
1783 | 1170 | 1170.0 | 45.87 | 45.9 | The projections of the ventral tegmental area and adjacent regions: a combined fluorescent retrograde tracer and immunofluorescence study in the rat. | L W Swanson | Brain Res Bull | 1982 | 6816390 | Yes |
1784 | 1170 | 1170.0 | 60.77 | 60.8 | Sample size in qualitative research. | M Sandelowski | Res Nurs Health | 1995 | 7899572 | Yes |
1785 | 2340 | 1170.0 | 51.92 | 26.0 | Short-term synaptic plasticity. | Robert S Zucker, Wade G Regehr | Annu Rev Physiol | 2002 | 11826273 | No |
1786 | 1170 | 1170.0 | 38.27 | 38.3 | The debate over dopamine's role in reward: the case for incentive salience. | Kent C Berridge | Psychopharmacology (Berl) | 2007 | 17072591 | No |
1787 | 4678 | 1169.5 | 0.0 | 0.0 | Antibiotic susceptibility testing by a standardized single disk method. | A W Bauer, W M Kirby, J C Sherris, M Turck | Am J Clin Pathol | 1966 | 5325707 | Yes |
1788 | 2338 | 1169.0 | 86.11 | 43.1 | Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. | K B Mullis, F A Faloona | Methods Enzymol | 1987 | 3431465 | Yes |
1789 | 1168 | 1168.0 | 36.01 | 36.0 | Steroid receptor regulated transcription of specific genes and gene networks. | K R Yamamoto | Annu Rev Genet | 1985 | 3909942 | No |
1790 | 1168 | 1168.0 | 22.27 | 22.3 | The snail superfamily of zinc-finger transcription factors. | M Angela Nieto | Nat Rev Mol Cell Biol | 2002 | 11994736 | No |
1791 | 2336 | 1168.0 | 51.27 | 25.6 | A guided tour into subcellular colocalization analysis in light microscopy. | S Bolte, F P Cordelières | J Microsc | 2006 | 17210054 | Yes |
1792 | 1167 | 1167.0 | 36.75 | 36.8 | A note on robust variance estimation for cluster-correlated data. | R L Williams | Biometrics | 2000 | 10877330 | Yes |
1793 | 1167 | 1167.0 | 46.94 | 46.9 | Functional and effective connectivity: a review. | Karl J Friston | Brain Connect | 2011 | 22432952 | No |
1794 | 2333 | 1166.5 | 52.86 | 26.4 | New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. | R D Gietz, A Sugino | Gene | 1988 | 3073106 | Yes |
1795 | 1165 | 1165.0 | 33.42 | 33.4 | Interoception: the sense of the physiological condition of the body. | A D Craig | Curr Opin Neurobiol | 2003 | 12965300 | No |
1796 | 3493 | 1164.3 | 106.83 | 35.6 | Regularization Paths for Generalized Linear Models via Coordinate Descent. | Jerome Friedman, Trevor Hastie, Rob Tibshirani | J Stat Softw | 2010 | 20808728 | Yes |
1797 | 2328 | 1164.0 | 53.56 | 26.8 | The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. | M S Brown, J L Goldstein | Cell | 1997 | 9150132 | No |
1798 | 1164 | 1164.0 | 43.25 | 43.2 | The functional gastrointestinal disorders and the Rome III process. | Douglas A Drossman | Gastroenterology | 2006 | 16678553 | No |
1799 | 3489 | 1163.0 | 0.0 | 0.0 | A rapid method for the isolation of functional thymus-derived murine lymphocytes. | M H Julius, E Simpson, L A Herzenberg | Eur J Immunol | 1973 | 4587740 | Yes |
1800 | 1163 | 1163.0 | 50.44 | 50.4 | Aging, natural death, and the compression of morbidity. | J F Fries | N Engl J Med | 1980 | 7383070 | Yes |
1801 | 1163 | 1163.0 | 25.89 | 25.9 | Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators. | R I Morimoto | Genes Dev | 1998 | 9869631 | No |
1802 | 1163 | 1163.0 | 27.62 | 27.6 | Autophagy: from phenomenology to molecular understanding in less than a decade. | Daniel J Klionsky | Nat Rev Mol Cell Biol | 2007 | 17712358 | No |
1803 | 3489 | 1163.0 | 166.53 | 55.5 | Molecular mechanisms of epithelial-mesenchymal transition. | Samy Lamouille, Jian Xu, Rik Derynck | Nat Rev Mol Cell Biol | 2014 | 24556840 | No |
1804 | 2324 | 1162.0 | 62.5 | 31.2 | Multipoint quantitative-trait linkage analysis in general pedigrees. | L Almasy, J Blangero | Am J Hum Genet | 1998 | 9545414 | Yes |
1805 | 1162 | 1162.0 | 28.27 | 28.3 | Mitochondria: dynamic organelles in disease, aging, and development. | David C Chan | Cell | 2006 | 16814712 | No |
1806 | 1161 | 1161.0 | 0.0 | 0.0 | Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction. | B Hille | J Gen Physiol | 1977 | 300786 | Yes |
1807 | 1161 | 1161.0 | 63.25 | 63.2 | Neurogenetic adaptive mechanisms in alcoholism. | C R Cloninger | Science | 1987 | 2882604 | Yes |
1808 | 1161 | 1161.0 | 0.0 | 0.0 | Application of a microtechnique to viral serological investigations. | J L SEVER | J Immunol | 1962 | 13910995 | Yes |
1809 | 1160 | 1160.0 | 0.0 | 0.0 | Mate selection-a selection for a handicap. | A Zahavi | J Theor Biol | 1975 | 1195756 | Yes |
1810 | 1160 | 1160.0 | 44.57 | 44.6 | G proteins and dual control of adenylate cyclase. | A G Gilman | Cell | 1984 | 6321035 | Yes |
1811 | 1160 | 1160.0 | 36.43 | 36.4 | The epidemiology of venous thromboembolism. | Richard H White | Circulation | 2003 | 12814979 | No |
1812 | 2319 | 1159.5 | 59.19 | 29.6 | An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. | A A Beg, D Baltimore | Science | 1996 | 8864118 | Yes |
1813 | 2319 | 1159.5 | 44.19 | 22.1 | Rab proteins as membrane organizers. | M Zerial, H McBride | Nat Rev Mol Cell Biol | 2001 | 11252952 | No |
1814 | 1159 | 1159.0 | 60.87 | 60.9 | A comparison of the two one-sided tests procedure and the power approach for assessing the equivalence of average bioavailability. | D J Schuirmann | J Pharmacokinet Biopharm | 1987 | 3450848 | Yes |
1815 | 2318 | 1159.0 | 120.89 | 60.4 | Dermatology Life Quality Index (DLQI)--a simple practical measure for routine clinical use. | A Y Finlay, G K Khan | Clin Exp Dermatol | 1994 | 8033378 | Yes |
1816 | 1159 | 1159.0 | 27.66 | 27.7 | Cancer of the ovary. | Stephen A Cannistra | N Engl J Med | 2004 | 15590954 | No |
1817 | 1159 | 1159.0 | 41.23 | 41.2 | Optimization of parameters for semiempirical methods V: modification of NDDO approximations and application to 70 elements. | James J P Stewart | J Mol Model | 2007 | 17828561 | Yes |
1818 | 1158 | 1158.0 | 33.58 | 33.6 | Membrane protein structure prediction. Hydrophobicity analysis and the positive-inside rule. | G von Heijne | J Mol Biol | 1992 | 1593632 | Yes |
1819 | 1158 | 1158.0 | 28.57 | 28.6 | Hyaluronan: from extracellular glue to pericellular cue. | Bryan P Toole | Nat Rev Cancer | 2004 | 15229478 | No |
1820 | 1157 | 1157.0 | 0.0 | 0.0 | RNA-dependent DNA polymerase in virions of RNA tumour viruses. | D Baltimore | Nature | 1970 | 4316300 | Yes |
1821 | 1157 | 1157.0 | 45.96 | 46.0 | The global impact of pre-eclampsia and eclampsia. | Lelia Duley | Semin Perinatol | 2009 | 19464502 | No |
1822 | 1156 | 1156.0 | 29.92 | 29.9 | Cell signaling. H2O2, a necessary evil for cell signaling. | Sue Goo Rhee | Science | 2006 | 16809515 | Yes |
1823 | 2311 | 1155.5 | 87.75 | 43.9 | Performing the exact test of Hardy-Weinberg proportion for multiple alleles. | S W Guo, E A Thompson | Biometrics | 1992 | 1637966 | Yes |
1824 | 1155 | 1155.0 | 0.0 | 0.0 | Specific pharmacology of calcium in myocardium, cardiac pacemakers, and vascular smooth muscle. | A Fleckenstein | Annu Rev Pharmacol Toxicol | 1977 | 326161 | No |
1825 | 1155 | 1155.0 | 97.63 | 97.6 | The Knee Society total knee arthroplasty roentgenographic evaluation and scoring system. | F C Ewald | Clin Orthop Relat Res | 1989 | 2805502 | Yes |
1826 | 1155 | 1155.0 | 28.0 | 28.0 | Protein misfolding, evolution and disease. | C M Dobson | Trends Biochem Sci | 1999 | 10470028 | No |
1827 | 1155 | 1155.0 | 47.53 | 47.5 | Optimal caliper widths for propensity-score matching when estimating differences in means and differences in proportions in observational studies. | Peter C Austin | Pharm Stat | 2011 | 20925139 | Yes |
1828 | 1154 | 1154.0 | 31.52 | 31.5 | Regulation of differentiation of vascular smooth muscle cells. | G K Owens | Physiol Rev | 1995 | 7624392 | No |
1829 | 2308 | 1154.0 | 82.73 | 41.4 | Biochemistry of multidrug resistance mediated by the multidrug transporter. | M M Gottesman, I Pastan | Annu Rev Biochem | 1993 | 8102521 | No |
1830 | 1154 | 1154.0 | 0.0 | 0.0 | The etiology of chondromalacia patellae. | R E OUTERBRIDGE | J Bone Joint Surg Br | 1961 | 14038135 | Yes |
1831 | 2307 | 1153.5 | 77.03 | 38.5 | A perspective on cancer cell metastasis. | Christine L Chaffer, Robert A Weinberg | Science | 2011 | 21436443 | No |
1832 | 1153 | 1153.0 | 38.13 | 38.1 | Redox signaling: nitrosylation and related target interactions of nitric oxide. | J S Stamler | Cell | 1994 | 7923362 | No |
1833 | 2304 | 1152.0 | 0.0 | 0.0 | New Giemsa method for the differential staining of sister chromatids. | P Perry, S Wolff | Nature | 1974 | 4138930 | Yes |
1834 | 1152 | 1152.0 | 63.43 | 63.4 | What's in a name? Qualitative description revisited. | Margarete Sandelowski | Res Nurs Health | 2010 | 20014004 | Yes |
1835 | 2302 | 1151.0 | 0.0 | 0.0 | The structure of coping. | L I Pearlin, C Schooler | J Health Soc Behav | 1978 | 649936 | Yes |
1836 | 2302 | 1151.0 | 86.0 | 43.0 | Functional architecture of basal ganglia circuits: neural substrates of parallel processing. | G E Alexander, M D Crutcher | Trends Neurosci | 1990 | 1695401 | No |
1837 | 1151 | 1151.0 | 42.08 | 42.1 | Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance. | L Bravo | Nutr Rev | 1998 | 9838798 | No |
1838 | 1151 | 1151.0 | 30.97 | 31.0 | Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study). | K M Fox | Lancet | 2003 | 13678872 | Yes |
1839 | 2301 | 1150.5 | 54.02 | 27.0 | LTP and LTD: an embarrassment of riches. | Robert C Malenka, Mark F Bear | Neuron | 2004 | 15450156 | No |
1840 | 2299 | 1149.5 | 80.63 | 40.3 | Individual differences in two emotion regulation processes: implications for affect, relationships, and well-being. | James J Gross, Oliver P John | J Pers Soc Psychol | 2003 | 12916575 | Yes |
1841 | 1149 | 1149.0 | 0.0 | 0.0 | Microbial ecology of the gastrointestinal tract. | D C Savage | Annu Rev Microbiol | 1977 | 334036 | No |
1842 | 1149 | 1149.0 | 0.0 | 0.0 | Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection. | W H Oldendorf | Am J Physiol | 1971 | 5124307 | Yes |
1843 | 1147 | 1147.0 | 37.22 | 37.2 | Capacitative calcium entry revisited. | J W Putney | Cell Calcium | 1990 | 1965707 | No |
1844 | 2294 | 1147.0 | 0.0 | 0.0 | The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. | A E Bolton, W M Hunter | Biochem J | 1973 | 4733239 | Yes |
1845 | 1147 | 1147.0 | 50.09 | 50.1 | Frontal-subcortical circuits and human behavior. | J L Cummings | Arch Neurol | 1993 | 8352676 | No |
1846 | 1147 | 1147.0 | 33.99 | 34.0 | Genetic consequences of climatic oscillations in the Quaternary. | G M Hewitt | Philos Trans R Soc Lond B Biol Sci | 2004 | 15101575 | No |
1847 | 1147 | 1147.0 | 63.64 | 63.6 | Gctf: Real-time CTF determination and correction. | Kai Zhang | J Struct Biol | 2016 | 26592709 | Yes |
1848 | 2292 | 1146.0 | 68.94 | 34.5 | The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. | P Angel, M Karin | Biochim Biophys Acta | 1991 | 1751545 | No |
1849 | 1146 | 1146.0 | 75.53 | 75.5 | Conservation of resources. A new attempt at conceptualizing stress. | S E Hobfoll | Am Psychol | 1989 | 2648906 | No |
1850 | 1146 | 1146.0 | 32.12 | 32.1 | Two pathogenetic types of endometrial carcinoma. | J V Bokhman | Gynecol Oncol | 1983 | 6822361 | Yes |
1851 | 1146 | 1146.0 | 42.7 | 42.7 | Strong localization of photons in certain disordered dielectric superlattices. | John | Phys Rev Lett | 1987 | 10034761 | Yes |
1852 | 1146 | 1146.0 | 0.0 | 0.0 | CHROMATOGRAPHIC SEPARATION OF HUMAN BRAIN GANGLIOSIDES. | L SVENNERHOLM | J Neurochem | 1963 | 14066623 | Yes |
1853 | 1146 | 1146.0 | 0.0 | 0.0 | The Interaction of Selection and Linkage. I. General Considerations; Heterotic Models. | R C Lewontin | Genetics | 1964 | 17248194 | Yes |
1854 | 2291 | 1145.5 | 0.0 | 0.0 | Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids. | A J Berk, P A Sharp | Cell | 1977 | 922889 | Yes |
1855 | 2291 | 1145.5 | 114.65 | 57.3 | Deciphering key features in protein structures with the new ENDscript server. | Xavier Robert, Patrice Gouet | Nucleic Acids Res | 2014 | 24753421 | Yes |
1856 | 2289 | 1144.5 | 52.86 | 26.4 | Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. | J M Kyriakis, J Avruch | Physiol Rev | 2001 | 11274345 | No |
1857 | 1144 | 1144.0 | 40.4 | 40.4 | Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum. | A Fabiato | Am J Physiol | 1983 | 6346892 | No |
1858 | 1144 | 1144.0 | 37.67 | 37.7 | Molecular bases of the acute coronary syndromes. | P Libby | Circulation | 1995 | 7758192 | No |
1859 | 1144 | 1144.0 | 34.25 | 34.2 | Hemispheric asymmetry reduction in older adults: the HAROLD model. | Roberto Cabeza | Psychol Aging | 2002 | 11931290 | No |
1860 | 2288 | 1144.0 | 85.99 | 43.0 | Density functionals with broad applicability in chemistry. | Yan Zhao, Donald G Truhlar | Acc Chem Res | 2008 | 18186612 | Yes |
1861 | 2287 | 1143.5 | 93.31 | 46.7 | Measuring emotion: the Self-Assessment Manikin and the Semantic Differential. | M M Bradley, P J Lang | J Behav Ther Exp Psychiatry | 1994 | 7962581 | Yes |
1862 | 2286 | 1143.0 | 0.0 | 0.0 | Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene. | M Grunstein, D S Hogness | Proc Natl Acad Sci U S A | 1975 | 1105573 | Yes |
1863 | 1143 | 1143.0 | 51.26 | 51.3 | Microalbuminuria predicts clinical proteinuria and early mortality in maturity-onset diabetes. | C E Mogensen | N Engl J Med | 1984 | 6690964 | Yes |
1864 | 1143 | 1143.0 | 35.09 | 35.1 | Hydrogels for biomedical applications. | Allan S Hoffman | Adv Drug Deliv Rev | 2002 | 11755703 | No |
1865 | 1143 | 1143.0 | 29.8 | 29.8 | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. | Nigel Unwin | J Mol Biol | 2005 | 15701510 | Yes |
1866 | 2285 | 1142.5 | 71.9 | 36.0 | The expanding universe of T-cell subsets: Th1, Th2 and more. | T R Mosmann, S Sad | Immunol Today | 1996 | 8820272 | No |
1867 | 2285 | 1142.5 | 61.84 | 30.9 | NF-kappa B: ten years after. | P A Baeuerle, D Baltimore | Cell | 1996 | 8858144 | No |
1868 | 1142 | 1142.0 | 56.95 | 57.0 | A structured interview guide for the Hamilton Depression Rating Scale. | J B Williams | Arch Gen Psychiatry | 1988 | 3395203 | Yes |
1869 | 2284 | 1142.0 | 47.35 | 23.7 | Autophagy as a regulated pathway of cellular degradation. | D J Klionsky, S D Emr | Science | 2000 | 11099404 | No |
1870 | 1142 | 1142.0 | 34.96 | 35.0 | The importance of the ratio of omega-6/omega-3 essential fatty acids. | A P Simopoulos | Biomed Pharmacother | 2002 | 12442909 | No |
1871 | 4565 | 1141.2 | 218.36 | 54.6 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | Int J Surg | 2010 | 20171303 | No |
1872 | 1140 | 1140.0 | 35.96 | 36.0 | Thioredoxin and glutaredoxin systems. | A Holmgren | J Biol Chem | 1989 | 2668278 | No |
1873 | 1140 | 1140.0 | 20.1 | 20.1 | The economics of ribosome biosynthesis in yeast. | J R Warner | Trends Biochem Sci | 1999 | 10542411 | No |
1874 | 1140 | 1140.0 | 22.19 | 22.2 | Regulatory T cells: key controllers of immunologic self-tolerance. | S Sakaguchi | Cell | 2000 | 10850488 | No |
1875 | 10252 | 1139.1 | 396.22 | 44.0 | STAR: ultrafast universal RNA-seq aligner. | Alexander Dobin, Carrie A Davis, Felix Schlesinger, Jorg Drenkow, Chris Zaleski, Sonali Jha, Philippe Batut, Mark Chaisson, Thomas R Gingeras | Bioinformatics | 2013 | 23104886 | Yes |
1876 | 1139 | 1139.0 | 45.16 | 45.2 | The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate. | G R Buettner | Arch Biochem Biophys | 1993 | 8434935 | No |
1877 | 1138 | 1138.0 | 31.92 | 31.9 | Drug-induced prolongation of the QT interval. | Dan M Roden | N Engl J Med | 2004 | 14999113 | No |
1878 | 1138 | 1138.0 | 31.76 | 31.8 | Marine viruses--major players in the global ecosystem. | Curtis A Suttle | Nat Rev Microbiol | 2007 | 17853907 | No |
1879 | 1138 | 1138.0 | 25.26 | 25.3 | Maintenance of C. elegans. | Theresa Stiernagle | WormBook | 2006 | 18050451 | No |
1880 | 3412 | 1137.3 | 110.24 | 36.7 | I-TASSER: a unified platform for automated protein structure and function prediction. | Ambrish Roy, Alper Kucukural, Yang Zhang | Nat Protoc | 2010 | 20360767 | Yes |
1881 | 1137 | 1137.0 | 19.62 | 19.6 | Cancer. Addiction to oncogenes--the Achilles heal of cancer. | I Bernard Weinstein | Science | 2002 | 12098689 | No |
1882 | 2274 | 1137.0 | 69.04 | 34.5 | Molecular mechanisms of long noncoding RNAs. | Kevin C Wang, Howard Y Chang | Mol Cell | 2011 | 21925379 | No |
1883 | 1137 | 1137.0 | 46.65 | 46.6 | Asthma phenotypes: the evolution from clinical to molecular approaches. | Sally E Wenzel | Nat Med | 2012 | 22561835 | No |
1884 | 2273 | 1136.5 | 0.0 | 0.0 | A scaled version of the General Health Questionnaire. | D P Goldberg, V F Hillier | Psychol Med | 1979 | 424481 | Yes |
1885 | 2273 | 1136.5 | 65.71 | 32.9 | Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. | E S Lander, D Botstein | Genetics | 1989 | 2563713 | Yes |
1886 | 1136 | 1136.0 | 35.94 | 35.9 | Bioactive microbial metabolites. | János Bérdy | J Antibiot (Tokyo) | 2005 | 15813176 | No |
1887 | 2271 | 1135.5 | 61.99 | 31.0 | Interneurons of the hippocampus. | T F Freund, G Buzsáki | Hippocampus | 1996 | 8915675 | No |
1888 | 2271 | 1135.5 | 77.35 | 38.7 | Astrocytes: biology and pathology. | Michael V Sofroniew, Harry V Vinters | Acta Neuropathol | 2010 | 20012068 | No |
1889 | 1135 | 1135.0 | 23.55 | 23.6 | NK cell receptors. | L L Lanier | Annu Rev Immunol | 1998 | 9597134 | No |
1890 | 2270 | 1135.0 | 0.0 | 0.0 | A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. | J E TILL, E A McCULLOCH | Radiat Res | 1961 | 13776896 | Yes |
1891 | 1134 | 1134.0 | 51.52 | 51.5 | Serum albumin. | T Peters | Adv Protein Chem | 1985 | 3904348 | No |
1892 | 1134 | 1134.0 | 0.0 | 0.0 | Electroimmuno assay. | C B Laurell | Scand J Clin Lab Invest Suppl | 1972 | 4114358 | Yes |
1893 | 2268 | 1134.0 | 83.47 | 41.7 | The pathogenesis of rheumatoid arthritis. | Iain B McInnes, Georg Schett | N Engl J Med | 2011 | 22150039 | No |
1894 | 6803 | 1133.8 | 269.35 | 44.9 | TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. | Daehwan Kim, Geo Pertea, Cole Trapnell, Harold Pimentel, Ryan Kelley, Steven L Salzberg | Genome Biol | 2013 | 23618408 | Yes |
1895 | 2267 | 1133.5 | 102.37 | 51.2 | The Oswestry Disability Index. | J C Fairbank, P B Pynsent | Spine (Phila Pa 1976) | 2000 | 11074683 | No |
1896 | 2267 | 1133.5 | 70.33 | 35.2 | Materials for electrochemical capacitors. | Patrice Simon, Yury Gogotsi | Nat Mater | 2008 | 18956000 | Yes |
1897 | 1133 | 1133.0 | 44.83 | 44.8 | Metalloproteinases and their inhibitors in matrix remodeling. | L M Matrisian | Trends Genet | 1990 | 2132731 | No |
1898 | 1133 | 1133.0 | 36.56 | 36.6 | A more meaningful scoring system for determining the severity of coronary heart disease. | G G Gensini | Am J Cardiol | 1983 | 6823874 | Yes |
1899 | 1133 | 1133.0 | 31.18 | 31.2 | Functions of ceramide in coordinating cellular responses to stress. | Y A Hannun | Science | 1996 | 8943189 | No |
1900 | 2266 | 1133.0 | 54.67 | 27.3 | Cellular senescence: when bad things happen to good cells. | Judith Campisi, Fabrizio d'Adda di Fagagna | Nat Rev Mol Cell Biol | 2007 | 17667954 | No |
1901 | 2264 | 1132.0 | 0.0 | 0.0 | Synchronization of Plasmodium falciparum erythrocytic stages in culture. | C Lambros, J P Vanderberg | J Parasitol | 1979 | 383936 | Yes |
1902 | 1132 | 1132.0 | 46.28 | 46.3 | Overcoming the absence of socioeconomic data in medical records: validation and application of a census-based methodology. | N Krieger | Am J Public Health | 1992 | 1566949 | Yes |
1903 | 2264 | 1132.0 | 50.91 | 25.5 | The molecular biology of axon guidance. | M Tessier-Lavigne, C S Goodman | Science | 1996 | 8895455 | No |
1904 | 2263 | 1131.5 | 0.0 | 0.0 | Junctional complexes in various epithelia. | M G FARQUHAR, G E PALADE | J Cell Biol | 1963 | 13944428 | Yes |
1905 | 2263 | 1131.5 | 58.38 | 29.2 | The DNA damage response: making it safe to play with knives. | Alberto Ciccia, Stephen J Elledge | Mol Cell | 2010 | 20965415 | No |
1906 | 1131 | 1131.0 | 0.0 | 0.0 | PLASTIC EMBEDDING MIXTURES FOR USE IN ELECTRON MICROSCOPY. | H H MOLLENHAUER | Stain Technol | 1964 | 14127791 | Yes |
1907 | 2260 | 1130.0 | 74.41 | 37.2 | CLUMPP: a cluster matching and permutation program for dealing with label switching and multimodality in analysis of population structure. | Mattias Jakobsson, Noah A Rosenberg | Bioinformatics | 2007 | 17485429 | Yes |
1908 | 3386 | 1128.7 | 103.65 | 34.6 | How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. | R M Sapolsky, L M Romero, A U Munck | Endocr Rev | 2000 | 10696570 | No |
1909 | 4514 | 1128.5 | 217.89 | 54.5 | Bayesian phylogenetics with BEAUti and the BEAST 1.7. | Alexei J Drummond, Marc A Suchard, Dong Xie, Andrew Rambaut | Mol Biol Evol | 2012 | 22367748 | Yes |
1910 | 1128 | 1128.0 | 0.0 | 0.0 | Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining. | A Krishan | J Cell Biol | 1975 | 49354 | Yes |
1911 | 2256 | 1128.0 | 0.0 | 0.0 | Computed circular dichroism spectra for the evaluation of protein conformation. | N Greenfield, G D Fasman | Biochemistry | 1969 | 5346390 | Yes |
1912 | 1128 | 1128.0 | 38.01 | 38.0 | Circuitry and functional aspects of the insular lobe in primates including humans. | J R Augustine | Brain Res Brain Res Rev | 1996 | 8957561 | No |
1913 | 7894 | 1127.7 | 272.56 | 38.9 | Cancer statistics, 2008. | Ahmedin Jemal, Rebecca Siegel, Elizabeth Ward, Yongping Hao, Jiaquan Xu, Taylor Murray, Michael J Thun | CA Cancer J Clin | 2008 | 18287387 | Yes |
1914 | 3383 | 1127.7 | 145.63 | 48.5 | CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. | Teresa C Horan, Mary Andrus, Margaret A Dudeck | Am J Infect Control | 2008 | 18538699 | No |
1915 | 2254 | 1127.0 | 65.89 | 32.9 | Abdominal obesity and metabolic syndrome. | Jean-Pierre Després, Isabelle Lemieux | Nature | 2006 | 17167477 | No |
1916 | 3380 | 1126.7 | 0.0 | 0.0 | Hydroperoxide metabolism in mammalian organs. | B Chance, H Sies, A Boveris | Physiol Rev | 1979 | 37532 | Yes |
1917 | 1125 | 1125.0 | 0.0 | 0.0 | Stimulated acoustic emissions from within the human auditory system. | D T Kemp | J Acoust Soc Am | 1978 | 744838 | Yes |
1918 | 2250 | 1125.0 | 83.86 | 41.9 | Polyamines. | C W Tabor, H Tabor | Annu Rev Biochem | 1984 | 6206782 | No |
1919 | 1125 | 1125.0 | 25.46 | 25.5 | The many faces of macrophage activation. | David M Mosser | J Leukoc Biol | 2003 | 12554797 | No |
1920 | 2249 | 1124.5 | 73.94 | 37.0 | Bronchopulmonary dysplasia. | A H Jobe, E Bancalari | Am J Respir Crit Care Med | 2001 | 11401896 | No |
1921 | 1124 | 1124.0 | 0.0 | 0.0 | Isolated removal of hypothalamic or other brain nuclei of the rat. | M Palkovits | Brain Res | 1973 | 4747772 | Yes |
1922 | 2248 | 1124.0 | 46.0 | 23.0 | Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. | C Li, W H Wong | Proc Natl Acad Sci U S A | 2001 | 11134512 | Yes |
1923 | 3372 | 1124.0 | 75.36 | 25.1 | The versatility and universality of calcium signalling. | M J Berridge, P Lipp, M D Bootman | Nat Rev Mol Cell Biol | 2000 | 11413485 | No |
1924 | 1124 | 1124.0 | 84.89 | 84.9 | The antibiotic resistance crisis: part 1: causes and threats. | C Lee Ventola | P T | 2015 | 25859123 | Yes |
1925 | 3371 | 1123.7 | 110.36 | 36.8 | A rapid bootstrap algorithm for the RAxML Web servers. | Alexandros Stamatakis, Paul Hoover, Jacques Rougemont | Syst Biol | 2008 | 18853362 | Yes |
1926 | 3370 | 1123.3 | 135.54 | 45.2 | Global estimates of the prevalence of diabetes for 2010 and 2030. | J E Shaw, R A Sicree, P Z Zimmet | Diabetes Res Clin Pract | 2010 | 19896746 | Yes |
1927 | 1123 | 1123.0 | 37.16 | 37.2 | Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation. | P Willner | Psychopharmacology (Berl) | 1997 | 9452163 | No |
1928 | 2246 | 1123.0 | 0.0 | 0.0 | Convergent and discriminant validation by the multitrait-multimethod matrix. | D T CAMPBELL, D W FISKE | Psychol Bull | 1959 | 13634291 | Yes |
1929 | 1123 | 1123.0 | 21.4 | 21.4 | SUMO: a history of modification. | Ronald T Hay | Mol Cell | 2005 | 15808504 | No |
1930 | 1123 | 1123.0 | 48.31 | 48.3 | Phase retrieval algorithms: a comparison. | J R Fienup | Appl Opt | 1982 | 20396114 | Yes |
1931 | 1122 | 1122.0 | 0.0 | 0.0 | The mechanism of muscular contraction. | H E Huxley | Science | 1969 | 4181952 | No |
1932 | 1122 | 1122.0 | 47.66 | 47.7 | The self-medication hypothesis of substance use disorders: a reconsideration and recent applications. | E J Khantzian | Harv Rev Psychiatry | 1997 | 9385000 | No |
1933 | 1121 | 1121.0 | 56.62 | 56.6 | Physiological aspects of primary hypertension. | B Folkow | Physiol Rev | 1982 | 6461865 | No |
1934 | 1121 | 1121.0 | 0.0 | 0.0 | The oxidation of ribonuclease with performic acid. | C H HIRS | J Biol Chem | 1956 | 13319283 | Yes |
1935 | 1121 | 1121.0 | 0.0 | 0.0 | THE RELATION OF RECOMBINATION TO MUTATIONAL ADVANCE. | H J MULLER | Mutat Res | 1964 | 14195748 | Yes |
1936 | 1120 | 1120.0 | 33.93 | 33.9 | Rapid and sensitive sequence comparison with FASTP and FASTA. | W R Pearson | Methods Enzymol | 1990 | 2156132 | Yes |
1937 | 1120 | 1120.0 | 33.65 | 33.6 | The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. | T Szkudelski | Physiol Res | 2001 | 11829314 | No |
1938 | 2240 | 1120.0 | 63.13 | 31.6 | A globally coherent fingerprint of climate change impacts across natural systems. | Camille Parmesan, Gary Yohe | Nature | 2003 | 12511946 | Yes |
1939 | 2240 | 1120.0 | 52.63 | 26.3 | Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry. | Joshua E Elias, Steven P Gygi | Nat Methods | 2007 | 17327847 | Yes |
1940 | 1120 | 1120.0 | 30.73 | 30.7 | Lead- and drug-like compounds: the rule-of-five revolution. | Christopher A Lipinski | Drug Discov Today Technol | 2004 | 24981612 | Yes |
1941 | 2239 | 1119.5 | 73.3 | 36.6 | Genome regulation by long noncoding RNAs. | John L Rinn, Howard Y Chang | Annu Rev Biochem | 2012 | 22663078 | No |
1942 | 2238 | 1119.0 | 78.1 | 39.0 | What's the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes. | J Zhang, K F Yu | JAMA | 1998 | 9832001 | Yes |
1943 | 2238 | 1119.0 | 73.8 | 36.9 | Epidemiology of invasive candidiasis: a persistent public health problem. | M A Pfaller, D J Diekema | Clin Microbiol Rev | 2007 | 17223626 | No |
1944 | 3354 | 1118.0 | 83.71 | 27.9 | Telomeres shorten during ageing of human fibroblasts. | C B Harley, A B Futcher, C W Greider | Nature | 1990 | 2342578 | Yes |
1945 | 2234 | 1117.0 | 68.68 | 34.3 | Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. | I Issemann, S Green | Nature | 1990 | 2129546 | Yes |
1946 | 2234 | 1117.0 | 45.33 | 22.7 | Oncogenic kinase signalling. | P Blume-Jensen, T Hunter | Nature | 2001 | 11357143 | No |
1947 | 1117 | 1117.0 | 27.72 | 27.7 | Mechanisms of foxp3+ T regulatory cell-mediated suppression. | Ethan M Shevach | Immunity | 2009 | 19464986 | No |
1948 | 1117 | 1117.0 | 41.66 | 41.7 | Stress and disorders of the stress system. | George P Chrousos | Nat Rev Endocrinol | 2009 | 19488073 | No |
1949 | 1116 | 1116.0 | 42.79 | 42.8 | Neurotransmitters and neuromodulators in the basal ganglia. | A M Graybiel | Trends Neurosci | 1990 | 1695398 | No |
1950 | 3348 | 1116.0 | 89.98 | 30.0 | The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. | S K Hanks, A M Quinn, T Hunter | Science | 1988 | 3291115 | No |
1951 | 1116 | 1116.0 | 25.31 | 25.3 | Endocytosis and molecular sorting. | I Mellman | Annu Rev Cell Dev Biol | 1996 | 8970738 | No |
1952 | 1116 | 1116.0 | 26.27 | 26.3 | Drug discovery: a historical perspective. | J Drews | Science | 2000 | 10720314 | No |
1953 | 1116 | 1116.0 | 35.29 | 35.3 | Synergy, antagonism, and what the chequerboard puts between them. | F C Odds | J Antimicrob Chemother | 2003 | 12805255 | No |
1954 | 4463 | 1115.8 | 157.18 | 39.3 | Reversible middle cerebral artery occlusion without craniectomy in rats. | E Z Longa, P R Weinstein, S Carlson, R Cummins | Stroke | 1989 | 2643202 | Yes |
1955 | 2231 | 1115.5 | 64.55 | 32.3 | The neural basis of human error processing: reinforcement learning, dopamine, and the error-related negativity. | Clay B Holroyd, Michael G H Coles | Psychol Rev | 2002 | 12374324 | Yes |
1956 | 2231 | 1115.5 | 63.98 | 32.0 | The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. | Daniel J Drucker, Michael A Nauck | Lancet | 2006 | 17098089 | No |
1957 | 1115 | 1115.0 | 37.0 | 37.0 | Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects. | E B Hunziker | Osteoarthritis Cartilage | 2002 | 12056848 | No |
1958 | 1114 | 1114.0 | 41.48 | 41.5 | Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. | M D Maines | FASEB J | 1988 | 3290025 | No |
1959 | 1114 | 1114.0 | 24.53 | 24.5 | Natively unfolded proteins: a point where biology waits for physics. | Vladimir N Uversky | Protein Sci | 2002 | 11910019 | No |
1960 | 1114 | 1114.0 | 32.5 | 32.5 | The human orbitofrontal cortex: linking reward to hedonic experience. | Morten L Kringelbach | Nat Rev Neurosci | 2005 | 16136173 | No |
1961 | 2228 | 1114.0 | 55.9 | 27.9 | Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. | Jane E Visvader, Geoffrey J Lindeman | Nat Rev Cancer | 2008 | 18784658 | No |
1962 | 1113 | 1113.0 | 58.2 | 58.2 | Negative symptoms in schizophrenia. Definition and reliability. | N C Andreasen | Arch Gen Psychiatry | 1982 | 7165477 | Yes |
1963 | 2226 | 1113.0 | 82.42 | 41.2 | The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. | J D Hayes, D J Pulford | Crit Rev Biochem Mol Biol | 1995 | 8770536 | No |
1964 | 1113 | 1113.0 | 45.68 | 45.7 | Deliberate practice and the acquisition and maintenance of expert performance in medicine and related domains. | K Anders Ericsson | Acad Med | 2004 | 15383395 | No |
1965 | 1113 | 1113.0 | 41.6 | 41.6 | The law of attrition. | Gunther Eysenbach | J Med Internet Res | 2005 | 15829473 | Yes |
1966 | 2226 | 1113.0 | 68.68 | 34.3 | Molecular replacement with MOLREP. | Alexei Vagin, Alexei Teplyakov | Acta Crystallogr D Biol Crystallogr | 2010 | 20057045 | Yes |
1967 | 2226 | 1113.0 | 53.55 | 26.8 | NMR View: A computer program for the visualization and analysis of NMR data. | B A Johnson, R A Blevins | J Biomol NMR | 1994 | 22911360 | Yes |
1968 | 1112 | 1112.0 | 0.0 | 0.0 | Estimability and estimation in case-referent studies. | O Miettinen | Am J Epidemiol | 1976 | 1251836 | Yes |
1969 | 3333 | 1111.0 | 90.81 | 30.3 | Thresholding of statistical maps in functional neuroimaging using the false discovery rate. | Christopher R Genovese, Nicole A Lazar, Thomas Nichols | Neuroimage | 2002 | 11906227 | Yes |
1970 | 2222 | 1111.0 | 0.0 | 0.0 | THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. II. SOLUBILIZATION, PURIFICATION, AND PROPERTIES. | T OMURA, R SATO | J Biol Chem | 1964 | 14209972 | Yes |
1971 | 2222 | 1111.0 | 75.4 | 37.7 | The cortical organization of speech processing. | Gregory Hickok, David Poeppel | Nat Rev Neurosci | 2007 | 17431404 | No |
1972 | 2221 | 1110.5 | 67.43 | 33.7 | The gut microbiota shapes intestinal immune responses during health and disease. | June L Round, Sarkis K Mazmanian | Nat Rev Immunol | 2009 | 19343057 | No |
1973 | 1110 | 1110.0 | 26.95 | 26.9 | The ATP synthase--a splendid molecular machine. | P D Boyer | Annu Rev Biochem | 1997 | 9242922 | No |
1974 | 1110 | 1110.0 | 26.96 | 27.0 | HIF-1: mediator of physiological and pathophysiological responses to hypoxia. | G L Semenza | J Appl Physiol (1985) | 2000 | 10749844 | No |
1975 | 1110 | 1110.0 | 31.0 | 31.0 | Clinical features of metastatic bone disease and risk of skeletal morbidity. | Robert E Coleman | Clin Cancer Res | 2006 | 17062708 | No |
1976 | 1110 | 1110.0 | 44.03 | 44.0 | Matching methods for causal inference: A review and a look forward. | Elizabeth A Stuart | Stat Sci | 2010 | 20871802 | Yes |
1977 | 6657 | 1109.5 | 189.49 | 31.6 | A default mode of brain function. | M E Raichle, A M MacLeod, A Z Snyder, W J Powers, D A Gusnard, G L Shulman | Proc Natl Acad Sci U S A | 2001 | 11209064 | Yes |
1978 | 2218 | 1109.0 | 76.8 | 38.4 | Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. | C J Murray, A D Lopez | Lancet | 1997 | 9164317 | Yes |
1979 | 1109 | 1109.0 | 42.14 | 42.1 | Aging, cellular senescence, and cancer. | Judith Campisi | Annu Rev Physiol | 2013 | 23140366 | No |
1980 | 1109 | 1109.0 | 58.34 | 58.3 | Whatever next? Predictive brains, situated agents, and the future of cognitive science. | Andy Clark | Behav Brain Sci | 2013 | 23663408 | No |
1981 | 1108 | 1108.0 | 31.17 | 31.2 | The use of nanocrystals in biological detection. | Paul Alivisatos | Nat Biotechnol | 2004 | 14704706 | Yes |
1982 | 1107 | 1107.0 | 38.2 | 38.2 | Treatment of infections associated with surgical implants. | Rabih O Darouiche | N Engl J Med | 2004 | 15070792 | No |
1983 | 2213 | 1106.5 | 96.61 | 48.3 | Universal chemical assay for the detection and determination of siderophores. | B Schwyn, J B Neilands | Anal Biochem | 1987 | 2952030 | Yes |
1984 | 2213 | 1106.5 | 112.62 | 56.3 | Natural products as sources of new drugs over the 30 years from 1981 to 2010. | David J Newman, Gordon M Cragg | J Nat Prod | 2012 | 22316239 | No |
1985 | 1106 | 1106.0 | 30.85 | 30.9 | The cadherins: cell-cell adhesion molecules controlling animal morphogenesis. | M Takeichi | Development | 1988 | 3048970 | No |
1986 | 1106 | 1106.0 | 20.28 | 20.3 | Clonal selection and learning in the antibody system. | K Rajewsky | Nature | 1996 | 8657279 | No |
1987 | 2211 | 1105.5 | 103.4 | 51.7 | A sensitive silver stain for detecting lipopolysaccharides in polyacrylamide gels. | C M Tsai, C E Frasch | Anal Biochem | 1982 | 6176137 | Yes |
1988 | 1105 | 1105.0 | 44.68 | 44.7 | Glutathione metabolism and its selective modification. | A Meister | J Biol Chem | 1988 | 3053703 | No |
1989 | 1105 | 1105.0 | 33.35 | 33.4 | Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders. | R M Sapolsky | Arch Gen Psychiatry | 2000 | 11015810 | No |
1990 | 1105 | 1105.0 | 38.61 | 38.6 | Chlorophyll fluorescence: a probe of photosynthesis in vivo. | Neil R Baker | Annu Rev Plant Biol | 2008 | 18444897 | No |
1991 | 2208 | 1104.0 | 0.0 | 0.0 | The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation. | E G GRAY, V P WHITTAKER | J Anat | 1962 | 13901297 | Yes |
1992 | 3311 | 1103.7 | 86.11 | 28.7 | Long non-coding RNAs: insights into functions. | Tim R Mercer, Marcel E Dinger, John S Mattick | Nat Rev Genet | 2009 | 19188922 | No |
1993 | 2207 | 1103.5 | 45.83 | 22.9 | Genetic transformation of Drosophila with transposable element vectors. | G M Rubin, A C Spradling | Science | 1982 | 6289436 | Yes |
1994 | 1103 | 1103.0 | 32.86 | 32.9 | Short-term synaptic plasticity. | R S Zucker | Annu Rev Neurosci | 1989 | 2648947 | No |
1995 | 3309 | 1103.0 | 76.14 | 25.4 | A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. | R Medzhitov, P Preston-Hurlburt, C A Janeway | Nature | 1997 | 9237759 | Yes |
1996 | 1103 | 1103.0 | 40.64 | 40.6 | Osteoblast adhesion on biomaterials. | K Anselme | Biomaterials | 2000 | 10711964 | No |
1997 | 1103 | 1103.0 | 0.0 | 0.0 | DITHIOTHREITOL, A NEW PROTECTIVE REAGENT FOR SH GROUPS. | W W CLELAND | Biochemistry | 1964 | 14192894 | Yes |
1998 | 1102 | 1102.0 | 55.04 | 55.0 | The role of hormone receptors and GTP-regulatory proteins in membrane transduction. | M Rodbell | Nature | 1980 | 6101906 | Yes |
1999 | 1102 | 1102.0 | 24.24 | 24.2 | The significance of responses of the genome to challenge. | B McClintock | Science | 1984 | 15739260 | No |
2000 | 2203 | 1101.5 | 75.54 | 37.8 | Angiogenesis. | J Folkman, Y Shing | J Biol Chem | 1992 | 1375931 | No |
2001 | 1101 | 1101.0 | 49.86 | 49.9 | Colorimetric determination of phospholipids with ammonium ferrothiocyanate. | J C Stewart | Anal Biochem | 1980 | 6892980 | Yes |
2002 | 1101 | 1101.0 | 30.29 | 30.3 | Two's company, three's a crowd: can H2S be the third endogenous gaseous transmitter? | Rui Wang | FASEB J | 2002 | 12409322 | Yes |
2003 | 2202 | 1101.0 | 66.52 | 33.3 | Regulation of chromatin by histone modifications. | Andrew J Bannister, Tony Kouzarides | Cell Res | 2011 | 21321607 | No |
2004 | 1100 | 1100.0 | 27.39 | 27.4 | E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. | J R Nevins | Science | 1992 | 1411535 | Yes |
2005 | 1100 | 1100.0 | 29.93 | 29.9 | Developmental cell death: morphological diversity and multiple mechanisms. | P G Clarke | Anat Embryol (Berl) | 1990 | 2186664 | No |
2006 | 3300 | 1100.0 | 96.96 | 32.3 | The metabolic syndrome. | Robert H Eckel, Scott M Grundy, Paul Z Zimmet | Lancet | 2005 | 15836891 | No |
2007 | 3300 | 1100.0 | 83.65 | 27.9 | Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? | Witold Filipowicz, Suvendra N Bhattacharyya, Nahum Sonenberg | Nat Rev Genet | 2008 | 18197166 | No |
2008 | 1100 | 1100.0 | 32.6 | 32.6 | The cancer stem cell: premises, promises and challenges. | Hans Clevers | Nat Med | 2011 | 21386835 | No |
2009 | 3298 | 1099.3 | 95.05 | 31.7 | Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer. | M A Frohman, M K Dush, G R Martin | Proc Natl Acad Sci U S A | 1988 | 2461560 | Yes |
2010 | 2198 | 1099.0 | 98.06 | 49.0 | Thermodynamics of protein association reactions: forces contributing to stability. | P D Ross, S Subramanian | Biochemistry | 1981 | 7248271 | Yes |
2011 | 1099 | 1099.0 | 50.81 | 50.8 | Presidential address, 1980. Surprise!...Surprise? | E Donchin | Psychophysiology | 1981 | 7280146 | Yes |
2012 | 1099 | 1099.0 | 47.9 | 47.9 | Functional organization of central pathways regulating the cardiovascular system. | R A Dampney | Physiol Rev | 1994 | 8171117 | No |
2013 | 2198 | 1099.0 | 62.22 | 31.1 | Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. | M P Lutolf, J A Hubbell | Nat Biotechnol | 2005 | 15637621 | No |
2014 | 2198 | 1099.0 | 170.5 | 85.2 | Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees. | Ivica Letunic, Peer Bork | Nucleic Acids Res | 2016 | 27095192 | Yes |
2015 | 1098 | 1098.0 | 47.15 | 47.1 | Metallothionein. | D H Hamer | Annu Rev Biochem | 1986 | 3527054 | No |
2016 | 1098 | 1098.0 | 36.51 | 36.5 | Graphene transistors. | Frank Schwierz | Nat Nanotechnol | 2010 | 20512128 | Yes |
2017 | 3292 | 1097.3 | 60.98 | 20.3 | A system for stable expression of short interfering RNAs in mammalian cells. | Thijn R Brummelkamp, René Bernards, Reuven Agami | Science | 2002 | 11910072 | Yes |
2018 | 2194 | 1097.0 | 74.89 | 37.4 | Mortality by cause for eight regions of the world: Global Burden of Disease Study. | C J Murray, A D Lopez | Lancet | 1997 | 9142060 | Yes |
2019 | 2194 | 1097.0 | 61.35 | 30.7 | Molecular beacons: probes that fluoresce upon hybridization. | S Tyagi, F R Kramer | Nat Biotechnol | 1996 | 9630890 | Yes |
2020 | 1097 | 1097.0 | 34.0 | 34.0 | Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. | Arnold I Caplan | J Cell Physiol | 2007 | 17620285 | No |
2021 | 6577 | 1096.2 | 209.03 | 34.8 | Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. | Roy G Brower, Michael A Matthay, Alan Morris, David Schoenfeld, B Taylor Thompson, Arthur Wheeler | N Engl J Med | 2000 | 10793162 | Yes |
2022 | 1096 | 1096.0 | 20.7 | 20.7 | The molecular motor toolbox for intracellular transport. | Ronald D Vale | Cell | 2003 | 12600311 | No |
2023 | 1096 | 1096.0 | 52.43 | 52.4 | MorphoJ: an integrated software package for geometric morphometrics. | Christian Peter Klingenberg | Mol Ecol Resour | 2011 | 21429143 | Yes |
2024 | 2191 | 1095.5 | 72.4 | 36.2 | Transforming growth factor beta in tissue fibrosis. | W A Border, N A Noble | N Engl J Med | 1994 | 7935686 | No |
2025 | 2190 | 1095.0 | 87.87 | 43.9 | Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art. | Johan W S Vlaeyen, Steven J Linton | Pain | 2000 | 10781906 | No |
2026 | 1095 | 1095.0 | 42.61 | 42.6 | Domino Reactions in Organic Synthesis. | Lutz F. Tietze | Chem Rev | 1996 | 11848746 | Yes |
2027 | 1095 | 1095.0 | 32.82 | 32.8 | Understanding biofilm resistance to antibacterial agents. | David Davies | Nat Rev Drug Discov | 2003 | 12563302 | No |
2028 | 1094 | 1094.0 | 38.42 | 38.4 | The many roles for fluorine in medicinal chemistry. | William K Hagmann | J Med Chem | 2008 | 18570365 | Yes |
2029 | 5469 | 1093.8 | 188.21 | 37.6 | Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. | Ronald C Kessler, Wai Tat Chiu, Olga Demler, Kathleen R Merikangas, Ellen E Walters | Arch Gen Psychiatry | 2005 | 15939839 | Yes |
2030 | 2187 | 1093.5 | 46.08 | 23.0 | Prediction of complete gene structures in human genomic DNA. | C Burge, S Karlin | J Mol Biol | 1997 | 9149143 | Yes |
2031 | 8746 | 1093.2 | 248.41 | 31.1 | Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. | N Tzourio-Mazoyer, B Landeau, D Papathanassiou, F Crivello, O Etard, N Delcroix, B Mazoyer, M Joliot | Neuroimage | 2002 | 11771995 | Yes |
2032 | 1093 | 1093.0 | 54.91 | 54.9 | Reliability and factor analysis of the Epworth Sleepiness Scale. | M W Johns | Sleep | 1992 | 1519015 | Yes |
2033 | 1093 | 1093.0 | 46.39 | 46.4 | Recent advances in the biochemistry of polyamines in eukaryotes. | A E Pegg | Biochem J | 1986 | 3087344 | No |
2034 | 1093 | 1093.0 | 0.0 | 0.0 | Solute perturbation of protein fluorescence. The quenching of the tryptophyl fluorescence of model compounds and of lysozyme by iodide ion. | S S Lehrer | Biochemistry | 1971 | 5119250 | Yes |
2035 | 1093 | 1093.0 | 43.83 | 43.8 | Turnover of inositol phospholipids and signal transduction. | Y Nishizuka | Science | 1984 | 6147898 | No |
2036 | 1093 | 1093.0 | 21.96 | 22.0 | Mobile elements: drivers of genome evolution. | Haig H Kazazian | Science | 2004 | 15016989 | No |
2037 | 2186 | 1093.0 | 0.0 | 0.0 | Mutations of Bacteria from Virus Sensitivity to Virus Resistance. | S E Luria, M Delbrück | Genetics | 1943 | 17247100 | Yes |
2038 | 12013 | 1092.1 | 334.98 | 30.5 | New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. | P Therasse, S G Arbuck, E A Eisenhauer, J Wanders, R S Kaplan, L Rubinstein, J Verweij, M Van Glabbeke, A T van Oosterom, M C Christian, S G Gwyther | J Natl Cancer Inst | 2000 | 10655437 | No |
2039 | 2184 | 1092.0 | 61.89 | 30.9 | Cell signaling by receptor tyrosine kinases. | Mark A Lemmon, Joseph Schlessinger | Cell | 2010 | 20602996 | No |
2040 | 7641 | 1091.6 | 409.44 | 58.5 | limma powers differential expression analyses for RNA-sequencing and microarray studies. | Matthew E Ritchie, Belinda Phipson, Di Wu, Yifang Hu, Charity W Law, Wei Shi, Gordon K Smyth | Nucleic Acids Res | 2015 | 25605792 | Yes |
2041 | 2183 | 1091.5 | 98.08 | 49.0 | The need to belong: desire for interpersonal attachments as a fundamental human motivation. | R F Baumeister, M R Leary | Psychol Bull | 1995 | 7777651 | No |
2042 | 4365 | 1091.2 | 0.0 | 0.0 | A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. | M A Markwell, S M Haas, L L Bieber, N E Tolbert | Anal Biochem | 1978 | 98070 | Yes |
2043 | 1091 | 1091.0 | 43.64 | 43.6 | Formation of glasses from liquids and biopolymers. | C A Angell | Science | 1995 | 17770101 | Yes |
2044 | 4363 | 1090.8 | 113.92 | 28.5 | Quantitative monitoring of gene expression patterns with a complementary DNA microarray. | M Schena, D Shalon, R W Davis, P O Brown | Science | 1995 | 7569999 | Yes |
2045 | 2181 | 1090.5 | 55.13 | 27.6 | Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. | P J Mitchell, R Tjian | Science | 1989 | 2667136 | No |
2046 | 1090 | 1090.0 | 40.33 | 40.3 | Biological basis of the behavior of sick animals. | B L Hart | Neurosci Biobehav Rev | 1988 | 3050629 | No |
2047 | 1090 | 1090.0 | 0.0 | 0.0 | Hippocampal electrical activity and voluntary movement in the rat. | C H Vanderwolf | Electroencephalogr Clin Neurophysiol | 1969 | 4183562 | Yes |
2048 | 1090 | 1090.0 | 34.54 | 34.5 | The sympathetic control of blood pressure. | Patrice G Guyenet | Nat Rev Neurosci | 2006 | 16760914 | No |
2049 | 3269 | 1089.7 | 138.57 | 46.2 | A new method for off-line removal of ocular artifact. | G Gratton, M G Coles, E Donchin | Electroencephalogr Clin Neurophysiol | 1983 | 6187540 | Yes |
2050 | 2179 | 1089.5 | 50.65 | 25.3 | Liver regeneration. | G K Michalopoulos, M C DeFrances | Science | 1997 | 9082986 | No |
2051 | 1089 | 1089.0 | 28.89 | 28.9 | Functions of the neurotrophins during nervous system development: what the knockouts are teaching us. | W D Snider | Cell | 1994 | 8205613 | No |
2052 | 1089 | 1089.0 | 29.56 | 29.6 | Optimal experimental design for event-related fMRI. | A M Dale | Hum Brain Mapp | 1999 | 10524601 | Yes |
2053 | 1089 | 1089.0 | 21.68 | 21.7 | microRNAs: tiny regulators with great potential. | V Ambros | Cell | 2001 | 11779458 | No |
2054 | 1089 | 1089.0 | 0.0 | 0.0 | Application of a Theory of Enzyme Specificity to Protein Synthesis. | D E Koshland | Proc Natl Acad Sci U S A | 1958 | 16590179 | Yes |
2055 | 1088 | 1088.0 | 0.0 | 0.0 | Biological applications of ionophores. | B C Pressman | Annu Rev Biochem | 1976 | 786156 | No |
2056 | 1088 | 1088.0 | 0.0 | 0.0 | A soluble protein characteristic of the nervous system. | B W Moore | Biochem Biophys Res Commun | 1965 | 4953930 | Yes |
2057 | 1088 | 1088.0 | 32.18 | 32.2 | Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides. | Y Shai | Biochim Biophys Acta | 1999 | 10590302 | No |
2058 | 2176 | 1088.0 | 90.97 | 45.5 | Genome editing. The new frontier of genome engineering with CRISPR-Cas9. | Jennifer A Doudna, Emmanuelle Charpentier | Science | 2014 | 25430774 | No |
2059 | 1088 | 1088.0 | 73.34 | 73.3 | Deep learning in neural networks: an overview. | Jürgen Schmidhuber | Neural Netw | 2015 | 25462637 | No |
2060 | 2174 | 1087.0 | 78.18 | 39.1 | An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. | Sun Ho Kim, Jin Mo Chung | Pain | 1992 | 1333581 | Yes |
2061 | 1087 | 1087.0 | 0.0 | 0.0 | CHEMOAFFINITY IN THE ORDERLY GROWTH OF NERVE FIBER PATTERNS AND CONNECTIONS. | R W SPERRY | Proc Natl Acad Sci U S A | 1963 | 14077501 | Yes |
2062 | 2174 | 1087.0 | 117.93 | 59.0 | A new initiative on precision medicine. | Francis S Collins, Harold Varmus | N Engl J Med | 2015 | 25635347 | Yes |
2063 | 1087 | 1087.0 | 66.89 | 66.9 | The biology and function of fibroblasts in cancer. | Raghu Kalluri | Nat Rev Cancer | 2016 | 27550820 | No |
2064 | 2173 | 1086.5 | 58.17 | 29.1 | The MAPK signaling cascade. | R Seger, E G Krebs | FASEB J | 1995 | 7601337 | No |
2065 | 1086 | 1086.0 | 20.99 | 21.0 | c-Myc target genes involved in cell growth, apoptosis, and metabolism. | C V Dang | Mol Cell Biol | 1999 | 9858526 | No |
2066 | 1086 | 1086.0 | 25.47 | 25.5 | The stem-cell niche as an entity of action. | David T Scadden | Nature | 2006 | 16810242 | No |
2067 | 1085 | 1085.0 | 0.0 | 0.0 | The biologic clock: the mitochondria? | D Harman | J Am Geriatr Soc | 1972 | 5016631 | Yes |
2068 | 1085 | 1085.0 | 33.81 | 33.8 | Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp. | D A Dougherty | Science | 1996 | 8539615 | No |
2069 | 2170 | 1085.0 | 61.13 | 30.6 | Pharmacology and functions of metabotropic glutamate receptors. | P J Conn, J P Pin | Annu Rev Pharmacol Toxicol | 1997 | 9131252 | No |
2070 | 1085 | 1085.0 | 41.18 | 41.2 | Ordinary magic. Resilience processes in development. | A S Masten | Am Psychol | 2001 | 11315249 | Yes |
2071 | 1084 | 1084.0 | 0.0 | 0.0 | The statistical analysis of enzyme kinetic data. | W W Cleland | Adv Enzymol Relat Areas Mol Biol | 1967 | 4881884 | No |
2072 | 1084 | 1084.0 | 74.21 | 74.2 | Presynaptic regulation of the release of catecholamines. | S Z Langer | Pharmacol Rev | 1980 | 6267618 | Yes |
2073 | 1084 | 1084.0 | 22.07 | 22.1 | CD95's deadly mission in the immune system. | P H Krammer | Nature | 2000 | 11048730 | No |
2074 | 2167 | 1083.5 | 57.04 | 28.5 | The RXR heterodimers and orphan receptors. | D J Mangelsdorf, R M Evans | Cell | 1995 | 8521508 | No |
2075 | 2167 | 1083.5 | 79.42 | 39.7 | Estimating wealth effects without expenditure data--or tears: an application to educational enrollments in states of India. | D Filmer, L H Pritchett | Demography | 2001 | 11227840 | Yes |
2076 | 2167 | 1083.5 | 79.29 | 39.6 | Porosity of 3D biomaterial scaffolds and osteogenesis. | Vassilis Karageorgiou, David Kaplan | Biomaterials | 2005 | 15860204 | No |
2077 | 1082 | 1082.0 | 28.71 | 28.7 | Fast and robust fixed-point algorithms for independent component analysis. | A Hyvärinen | IEEE Trans Neural Netw | 1999 | 18252563 | Yes |
2078 | 1082 | 1082.0 | 51.89 | 51.9 | Cognitive reserve in ageing and Alzheimer's disease. | Yaakov Stern | Lancet Neurol | 2012 | 23079557 | No |
2079 | 2163 | 1081.5 | 70.73 | 35.4 | Defining the clinical course of multiple sclerosis: results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. | F D Lublin, S C Reingold | Neurology | 1996 | 8780061 | Yes |
2080 | 1081 | 1081.0 | 59.26 | 59.3 | Mood and memory. | G H Bower | Am Psychol | 1981 | 7224324 | Yes |
2081 | 2162 | 1081.0 | 48.6 | 24.3 | Regulated portals of entry into the cell. | Sean D Conner, Sandra L Schmid | Nature | 2003 | 12621426 | No |
2082 | 1081 | 1081.0 | 29.57 | 29.6 | The blood-brain barrier: bottleneck in brain drug development. | William M Pardridge | NeuroRx | 2005 | 15717053 | No |
2083 | 2162 | 1081.0 | 99.78 | 49.9 | The integrative review: updated methodology. | Robin Whittemore, Kathleen Knafl | J Adv Nurs | 2005 | 16268861 | Yes |
2084 | 2162 | 1081.0 | 56.9 | 28.4 | Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. | Kornelia Polyak, Robert A Weinberg | Nat Rev Cancer | 2009 | 19262571 | No |
2085 | 2161 | 1080.5 | 0.0 | 0.0 | 3' non-coding region sequences in eukaryotic messenger RNA. | N J Proudfoot, G G Brownlee | Nature | 1976 | 822353 | Yes |
2086 | 1080 | 1080.0 | 45.41 | 45.4 | The SPQ: a scale for the assessment of schizotypal personality based on DSM-III-R criteria. | A Raine | Schizophr Bull | 1991 | 1805349 | Yes |
2087 | 1080 | 1080.0 | 54.9 | 54.9 | The validity and practicality of sun-reactive skin types I through VI. | T B Fitzpatrick | Arch Dermatol | 1988 | 3377516 | Yes |
2088 | 1080 | 1080.0 | 0.0 | 0.0 | Codon--anticodon pairing: the wobble hypothesis. | F H Crick | J Mol Biol | 1966 | 5969078 | Yes |
2089 | 1080 | 1080.0 | 46.15 | 46.1 | Plasma perspective on strong field multiphoton ionization. | Corkum | Phys Rev Lett | 1993 | 10054556 | Yes |
2090 | 1080 | 1080.0 | 30.12 | 30.1 | Proinflammatory cytokines. | C A Dinarello | Chest | 2000 | 10936147 | No |
2091 | 2159 | 1079.5 | 68.52 | 34.3 | What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience? | K C Berridge, T E Robinson | Brain Res Brain Res Rev | 1998 | 9858756 | No |
2092 | 3238 | 1079.3 | 145.62 | 48.5 | Effect of the damping function in dispersion corrected density functional theory. | Stefan Grimme, Stephan Ehrlich, Lars Goerigk | J Comput Chem | 2011 | 21370243 | Yes |
2093 | 1079 | 1079.0 | 28.56 | 28.6 | Codon usage and tRNA content in unicellular and multicellular organisms. | T Ikemura | Mol Biol Evol | 1985 | 3916708 | No |
2094 | 1079 | 1079.0 | 0.0 | 0.0 | A graphic method for the determination and presentation of binding parameters in a complex system. | H E Rosenthal | Anal Biochem | 1967 | 6048188 | Yes |
2095 | 1079 | 1079.0 | 38.69 | 38.7 | Chronic disease management: what will it take to improve care for chronic illness? | E H Wagner | Eff Clin Pract | 1998 | 10345255 | No |
2096 | 1079 | 1079.0 | 30.56 | 30.6 | Tobacco smoke carcinogens and lung cancer. | S S Hecht | J Natl Cancer Inst | 1999 | 10413421 | No |
2097 | 1079 | 1079.0 | 34.94 | 34.9 | Diagnosis of osteoporosis and assessment of fracture risk. | John A Kanis | Lancet | 2002 | 12057569 | No |
2098 | 1079 | 1079.0 | 26.54 | 26.5 | DNA damage, aging, and cancer. | Jan H J Hoeijmakers | N Engl J Med | 2009 | 19812404 | No |
2099 | 1078 | 1078.0 | 0.0 | 0.0 | Some observations upon a new inhibitor of monoamine oxidase in brain tissue. | J P Johnston | Biochem Pharmacol | 1968 | 5659776 | Yes |
2100 | 1078 | 1078.0 | 44.28 | 44.3 | Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data. | Thomas Heberer | Toxicol Lett | 2002 | 11988354 | Yes |
2101 | 2156 | 1078.0 | 51.86 | 25.9 | The pathophysiology of mitochondrial cell death. | Douglas R Green, Guido Kroemer | Science | 2004 | 15286356 | No |
2102 | 1078 | 1078.0 | 26.13 | 26.1 | Transcriptional control of adipocyte formation. | Stephen R Farmer | Cell Metab | 2006 | 17011499 | No |
2103 | 1077 | 1077.0 | 28.51 | 28.5 | Protein kinase C: structure, function, and regulation. | A C Newton | J Biol Chem | 1995 | 7499357 | No |
2104 | 3231 | 1077.0 | 102.25 | 34.1 | Atomic force microscope. | Binnig, Quate, Gerber | Phys Rev Lett | 1986 | 10033323 | Yes |
2105 | 2153 | 1076.5 | 79.44 | 39.7 | Glycine potentiates the NMDA response in cultured mouse brain neurons. | J W Johnson, P Ascher | Nature | 1987 | 2433595 | Yes |
2106 | 5382 | 1076.4 | 155.65 | 31.1 | Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. | Sarah Lewington, Robert Clarke, Nawab Qizilbash, Richard Peto, Rory Collins | Lancet | 2002 | 12493255 | Yes |
2107 | 3228 | 1076.0 | 77.42 | 25.8 | OrthoMCL: identification of ortholog groups for eukaryotic genomes. | Li Li, Christian J Stoeckert, David S Roos | Genome Res | 2003 | 12952885 | Yes |
2108 | 1076 | 1076.0 | 0.0 | 0.0 | Diversity in tropical rain forests and coral reefs. | J H Connell | Science | 1978 | 17840770 | Yes |
2109 | 2152 | 1076.0 | 79.98 | 40.0 | Oxidative stress and diabetic complications. | Ferdinando Giacco, Michael Brownlee | Circ Res | 2010 | 21030723 | No |
2110 | 1075 | 1075.0 | 41.96 | 42.0 | Equipoise and the ethics of clinical research. | B Freedman | N Engl J Med | 1987 | 3600702 | Yes |
2111 | 4299 | 1074.8 | 93.87 | 23.5 | Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. | D D Sarbassov, David A Guertin, Siraj M Ali, David M Sabatini | Science | 2005 | 15718470 | Yes |
2112 | 2149 | 1074.5 | 58.48 | 29.2 | Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. | D A Brown, J K Rose | Cell | 1992 | 1531449 | Yes |
2113 | 2149 | 1074.5 | 58.8 | 29.4 | Regulation mechanisms and signaling pathways of autophagy. | Congcong He, Daniel J Klionsky | Annu Rev Genet | 2009 | 19653858 | No |
2114 | 1074 | 1074.0 | 29.38 | 29.4 | Reactive oxygen radicals in signaling and damage in the ischemic brain. | P H Chan | J Cereb Blood Flow Metab | 2001 | 11149664 | No |
2115 | 1074 | 1074.0 | 31.27 | 31.3 | Microbial influences in inflammatory bowel diseases. | R Balfour Sartor | Gastroenterology | 2008 | 18242222 | No |
2116 | 2147 | 1073.5 | 42.6 | 21.3 | A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. | D Tautz, C Pfeifle | Chromosoma | 1989 | 2476281 | Yes |
2117 | 2147 | 1073.5 | 41.88 | 20.9 | DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. | Christopher J Bakkenist, Michael B Kastan | Nature | 2003 | 12556884 | Yes |
2118 | 1073 | 1073.0 | 35.53 | 35.5 | Multiple imputation of discrete and continuous data by fully conditional specification. | Stef van Buuren | Stat Methods Med Res | 2007 | 17621469 | Yes |
2119 | 1073 | 1073.0 | 0.0 | 0.0 | Phosphorus compounds in animal tissues; extraction and estimation of desoxypentose nucleic acid and of pentose nucleic acid. | W C SCHNEIDER | J Biol Chem | 1945 | 21005736 | Yes |
2120 | 2145 | 1072.5 | 53.97 | 27.0 | Mitochondrial control of cell death. | G Kroemer, J C Reed | Nat Med | 2000 | 10802706 | No |
2121 | 1072 | 1072.0 | 0.0 | 0.0 | Bias in analytic research. | D L Sackett | J Chronic Dis | 1979 | 447779 | Yes |
2122 | 1072 | 1072.0 | 61.22 | 61.2 | A new international staging system for lung cancer. | C F Mountain | Chest | 1986 | 3514171 | No |
2123 | 1072 | 1072.0 | 34.04 | 34.0 | The origins of the developmental origins theory. | D J P Barker | J Intern Med | 2007 | 17444880 | No |
2124 | 2143 | 1071.5 | 0.0 | 0.0 | Empirical predictions of protein conformation. | P Y Chou, G D Fasman | Annu Rev Biochem | 1978 | 354496 | No |
2125 | 2142 | 1071.0 | 46.42 | 23.2 | Gene silencing in cancer in association with promoter hypermethylation. | James G Herman, Stephen B Baylin | N Engl J Med | 2003 | 14627790 | No |
2126 | 1071 | 1071.0 | 29.53 | 29.5 | Upconversion and anti-Stokes processes with f and d ions in solids. | François Auzel | Chem Rev | 2004 | 14719973 | Yes |
2127 | 2141 | 1070.5 | 83.27 | 41.6 | Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. | D S Bredt, S H Snyder | Proc Natl Acad Sci U S A | 1990 | 1689048 | Yes |
2128 | 2141 | 1070.5 | 42.6 | 21.3 | Live or let die: the cell's response to p53. | Karen H Vousden, Xin Lu | Nat Rev Cancer | 2002 | 12154352 | No |
2129 | 2140 | 1070.0 | 62.44 | 31.2 | Neuronal plasticity: increasing the gain in pain. | C J Woolf, M W Salter | Science | 2000 | 10846153 | No |
2130 | 1069 | 1069.0 | 40.17 | 40.2 | Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: a hypothesis for the etiology of schizophrenia. | A A Grace | Neuroscience | 1991 | 1676137 | No |
2131 | 1069 | 1069.0 | 38.18 | 38.2 | Integrins. | E Ruoslahti | J Clin Invest | 1991 | 1985087 | No |
2132 | 2138 | 1069.0 | 90.65 | 45.3 | The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today. | R Doll, R Peto | J Natl Cancer Inst | 1981 | 7017215 | No |
2133 | 1069 | 1069.0 | 25.89 | 25.9 | Long-term potentiation and memory. | M A Lynch | Physiol Rev | 2004 | 14715912 | No |
2134 | 1069 | 1069.0 | 46.21 | 46.2 | Categorical Data Analysis: Away from ANOVAs (transformation or not) and towards Logit Mixed Models. | T Florian Jaeger | J Mem Lang | 2008 | 19884961 | Yes |
2135 | 1067 | 1067.0 | 43.85 | 43.9 | Inflammation in atherosclerosis. | Peter Libby | Arterioscler Thromb Vasc Biol | 2012 | 22895665 | No |
2136 | 1066 | 1066.0 | 24.52 | 24.5 | Searching for genetic determinants in the new millennium. | N J Risch | Nature | 2000 | 10866211 | No |
2137 | 1066 | 1066.0 | 38.39 | 38.4 | Signal transduction by reactive oxygen species. | Toren Finkel | J Cell Biol | 2011 | 21746850 | No |
2138 | 1065 | 1065.0 | 29.08 | 29.1 | The 'effective number of codons' used in a gene. | F Wright | Gene | 1990 | 2110097 | Yes |
2139 | 1065 | 1065.0 | 32.89 | 32.9 | Speculations on the functions of the major heat shock and glucose-regulated proteins. | H R Pelham | Cell | 1986 | 2944601 | Yes |
2140 | 1065 | 1065.0 | 0.0 | 0.0 | The theory and applications of the exchange of inert gas at the lungs and tissues. | S S KETY | Pharmacol Rev | 1951 | 14833874 | Yes |
2141 | 1065 | 1065.0 | 30.87 | 30.9 | Pain and emotion interactions in subregions of the cingulate gyrus. | Brent A Vogt | Nat Rev Neurosci | 2005 | 15995724 | No |
2142 | 2128 | 1064.0 | 70.81 | 35.4 | CLUSTAL: a package for performing multiple sequence alignment on a microcomputer. | D G Higgins, P M Sharp | Gene | 1988 | 3243435 | Yes |
2143 | 1064 | 1064.0 | 43.46 | 43.5 | SPSS and SAS programs for determining the number of components using parallel analysis and velicer's MAP test. | B P O'Connor | Behav Res Methods Instrum Comput | 2000 | 11029811 | Yes |
2144 | 2127 | 1063.5 | 59.62 | 29.8 | Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information. | M Zuker, P Stiegler | Nucleic Acids Res | 1981 | 6163133 | Yes |
2145 | 1063 | 1063.0 | 30.5 | 30.5 | Aspergillus fumigatus and aspergillosis. | J P Latgé | Clin Microbiol Rev | 1999 | 10194462 | No |
2146 | 1062 | 1062.0 | 25.19 | 25.2 | Dimerization of cell surface receptors in signal transduction. | C H Heldin | Cell | 1995 | 7834741 | No |
2147 | 1062 | 1062.0 | 25.82 | 25.8 | Topoisomerase I inhibitors: camptothecins and beyond. | Yves Pommier | Nat Rev Cancer | 2006 | 16990856 | No |
2148 | 4244 | 1061.0 | 107.12 | 26.8 | Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. | Eugenia E Calle, Carmen Rodriguez, Kimberly Walker-Thurmond, Michael J Thun | N Engl J Med | 2003 | 12711737 | Yes |
2149 | 1061 | 1061.0 | 39.06 | 39.1 | A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. | Ozcan Erel | Clin Biochem | 2004 | 15003729 | Yes |
2150 | 1061 | 1061.0 | 43.8 | 43.8 | The World Oral Health Report 2003: continuous improvement of oral health in the 21st century--the approach of the WHO Global Oral Health Programme. | Poul Erik Petersen | Community Dent Oral Epidemiol | 2003 | 15015736 | Yes |
2151 | 11661 | 1060.1 | 382.14 | 34.7 | The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. | Aram V Chobanian, George L Bakris, Henry R Black, William C Cushman, Lee A Green, Joseph L Izzo, Daniel W Jones, Barry J Materson, Suzanne Oparil, Jackson T Wright, Edward J Roccella | JAMA | 2003 | 12748199 | No |
2152 | 2120 | 1060.0 | 58.82 | 29.4 | Microglia: active sensor and versatile effector cells in the normal and pathologic brain. | Uwe-Karsten Hanisch, Helmut Kettenmann | Nat Neurosci | 2007 | 17965659 | No |
2153 | 4238 | 1059.5 | 109.86 | 27.5 | Base-calling of automated sequencer traces using phred. I. Accuracy assessment. | B Ewing, L Hillier, M C Wendl, P Green | Genome Res | 1998 | 9521921 | Yes |
2154 | 1059 | 1059.0 | 0.0 | 0.0 | Calcium release from the sarcoplasmic reticulum. | M Endo | Physiol Rev | 1977 | 13441 | Yes |
2155 | 1059 | 1059.0 | 0.0 | 0.0 | The measurement of volume changes in human limbs. | R J WHITNEY | J Physiol | 1953 | 13085295 | Yes |
2156 | 2117 | 1058.5 | 55.89 | 27.9 | Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. | M E Greenberg, E B Ziff | Nature | 1984 | 6090941 | Yes |
2157 | 1058 | 1058.0 | 55.76 | 55.8 | Cyclosporine. | B D Kahan | N Engl J Med | 1989 | 2687689 | No |
2158 | 1058 | 1058.0 | 30.33 | 30.3 | Overview of general physiologic features and functions of vitamin D. | Hector F DeLuca | Am J Clin Nutr | 2004 | 15585789 | No |
2159 | 2114 | 1057.0 | 0.0 | 0.0 | Regulatory sequences involved in the promotion and termination of RNA transcription. | M Rosenberg, D Court | Annu Rev Genet | 1979 | 94251 | No |
2160 | 1056 | 1056.0 | 37.69 | 37.7 | Isolation and cultivation of Lyme disease spirochetes. | A G Barbour | Yale J Biol Med | 1984 | 6393604 | Yes |
2161 | 1056 | 1056.0 | 35.46 | 35.5 | Varieties of impulsivity. | J L Evenden | Psychopharmacology (Berl) | 1999 | 10550486 | No |
2162 | 1056 | 1056.0 | 0.0 | 0.0 | Modality and topographic properties of single neurons of cat's somatic sensory cortex. | V B MOUNTCASTLE | J Neurophysiol | 1957 | 13439410 | Yes |
2163 | 1056 | 1056.0 | 34.33 | 34.3 | Polycystic ovary syndrome. | David A Ehrmann | N Engl J Med | 2005 | 15788499 | No |
2164 | 1056 | 1056.0 | 30.91 | 30.9 | Reconciling the chemistry and biology of reactive oxygen species. | Christine C Winterbourn | Nat Chem Biol | 2008 | 18421291 | No |
2165 | 3166 | 1055.3 | 72.73 | 24.2 | Calcium signalling: dynamics, homeostasis and remodelling. | Michael J Berridge, Martin D Bootman, H Llewelyn Roderick | Nat Rev Mol Cell Biol | 2003 | 12838335 | No |
2166 | 1055 | 1055.0 | 49.44 | 49.4 | Amyloid deposits and amyloidosis. The beta-fibrilloses (first of two parts). | G G Glenner | N Engl J Med | 1980 | 6154243 | No |
2167 | 3165 | 1055.0 | 75.29 | 25.1 | Multidrug resistance in cancer: role of ATP-dependent transporters. | Michael M Gottesman, Tito Fojo, Susan E Bates | Nat Rev Cancer | 2002 | 11902585 | No |
2168 | 1055 | 1055.0 | 32.52 | 32.5 | Atopic dermatitis. | Thomas Bieber | N Engl J Med | 2008 | 18385500 | Yes |
2169 | 1054 | 1054.0 | 0.0 | 0.0 | A simple method of increasing the adhesion of acrylic filling materials to enamel surfaces. | M G BUONOCORE | J Dent Res | 1955 | 13271655 | Yes |
2170 | 2108 | 1054.0 | 47.43 | 23.7 | ERBB receptors and cancer: the complexity of targeted inhibitors. | Nancy E Hynes, Heidi A Lane | Nat Rev Cancer | 2005 | 15864276 | No |
2171 | 6321 | 1053.5 | 177.31 | 29.6 | Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research. | Ana Conesa, Stefan Götz, Juan Miguel García-Gómez, Javier Terol, Manuel Talón, Montserrat Robles | Bioinformatics | 2005 | 16081474 | Yes |
2172 | 7372 | 1053.1 | 157.53 | 22.5 | Exploration, normalization, and summaries of high density oligonucleotide array probe level data. | Rafael A Irizarry, Bridget Hobbs, Francois Collin, Yasmin D Beazer-Barclay, Kristen J Antonellis, Uwe Scherf, Terence P Speed | Biostatistics | 2003 | 12925520 | Yes |
2173 | 1053 | 1053.0 | 31.91 | 31.9 | Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles. | M Kozak | Microbiol Rev | 1983 | 6343825 | No |
2174 | 2106 | 1053.0 | 52.45 | 26.2 | Self-assembly at all scales. | George M Whitesides, Bartosz Grzybowski | Science | 2002 | 11923529 | Yes |
2175 | 1053 | 1053.0 | 0.0 | 0.0 | Cerebral blood flow and oxygen consumption in man. | N A LASSEN | Physiol Rev | 1959 | 13645234 | Yes |
2176 | 1053 | 1053.0 | 28.11 | 28.1 | Pathways of oxidative damage. | James A Imlay | Annu Rev Microbiol | 2003 | 14527285 | No |
2177 | 2104 | 1052.0 | 54.58 | 27.3 | Disruption of epithelial cell-matrix interactions induces apoptosis. | S M Frisch, H Francis | J Cell Biol | 1994 | 8106557 | Yes |
2178 | 1052 | 1052.0 | 0.0 | 0.0 | A new specific color reaction of hexuronic acids. | Z DISCHE | J Biol Chem | 1947 | 20281638 | Yes |
2179 | 2103 | 1051.5 | 0.0 | 0.0 | Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. | J Altman, G D Das | J Comp Neurol | 1965 | 5861717 | Yes |
2180 | 1051 | 1051.0 | 31.17 | 31.2 | Rapid evolution of a protein in vitro by DNA shuffling. | W P Stemmer | Nature | 1994 | 8047147 | Yes |
2181 | 1051 | 1051.0 | 36.69 | 36.7 | Semiempirical hybrid density functional with perturbative second-order correlation. | Stefan Grimme | J Chem Phys | 2006 | 16438568 | Yes |
2182 | 3152 | 1050.7 | 111.04 | 37.0 | Simultaneous inference in general parametric models. | Torsten Hothorn, Frank Bretz, Peter Westfall | Biom J | 2008 | 18481363 | No |
2183 | 1050 | 1050.0 | 0.0 | 0.0 | Computerized transverse axial scanning (tomography). 1. Description of system. | G N Hounsfield | Br J Radiol | 1973 | 4757352 | Yes |
2184 | 1050 | 1050.0 | 0.0 | 0.0 | Carbonic anhydrase: chemistry, physiology, and inhibition. | T H Maren | Physiol Rev | 1967 | 4964060 | No |
2185 | 1050 | 1050.0 | 59.6 | 59.6 | Optical properties of biological tissues: a review. | Steven L Jacques | Phys Med Biol | 2013 | 23666068 | No |
2186 | 3149 | 1049.7 | 184.59 | 61.5 | Risk factors for falls among elderly persons living in the community. | M E Tinetti, M Speechley, S F Ginter | N Engl J Med | 1988 | 3205267 | Yes |
2187 | 2098 | 1049.0 | 0.0 | 0.0 | Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. | J E Sulston, H R Horvitz | Dev Biol | 1977 | 838129 | Yes |
2188 | 2098 | 1049.0 | 75.53 | 37.8 | The benefits of being present: mindfulness and its role in psychological well-being. | Kirk Warren Brown, Richard M Ryan | J Pers Soc Psychol | 2003 | 12703651 | Yes |
2189 | 1049 | 1049.0 | 0.0 | 0.0 | Fluorescent antibody methods. | A H COONS | Gen Cytochem Methods | 1958 | 13574437 | Yes |
2190 | 1048 | 1048.0 | 0.0 | 0.0 | The ultrastructural basis of capillary permeability studied with peroxidase as a tracer. | M J Karnovsky | J Cell Biol | 1967 | 6061717 | Yes |
2191 | 1048 | 1048.0 | 31.53 | 31.5 | Psychological and neural mechanisms of the affective dimension of pain. | D D Price | Science | 2000 | 10846154 | No |
2192 | 1048 | 1048.0 | 18.1 | 18.1 | Themes and variations on ubiquitylation. | A M Weissman | Nat Rev Mol Cell Biol | 2001 | 11265246 | No |
2193 | 1048 | 1048.0 | 29.43 | 29.4 | Primate anterior cingulate cortex: where motor control, drive and cognition interface. | T Paus | Nat Rev Neurosci | 2001 | 11389475 | No |
2194 | 1048 | 1048.0 | 24.51 | 24.5 | Neuroligins and neurexins link synaptic function to cognitive disease. | Thomas C Südhof | Nature | 2008 | 18923512 | No |
2195 | 3142 | 1047.3 | 0.0 | 0.0 | The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes. | J T DODGE, C MITCHELL, D J HANAHAN | Arch Biochem Biophys | 1963 | 14028302 | Yes |
2196 | 1047 | 1047.0 | 33.15 | 33.1 | Cellular oncogenes and retroviruses. | J M Bishop | Annu Rev Biochem | 1983 | 6351725 | No |
2197 | 1047 | 1047.0 | 50.68 | 50.7 | An outpatient program in behavioral medicine for chronic pain patients based on the practice of mindfulness meditation: theoretical considerations and preliminary results. | J Kabat-Zinn | Gen Hosp Psychiatry | 1982 | 7042457 | Yes |
2198 | 1047 | 1047.0 | 29.15 | 29.1 | Papillomavirus infections--a major cause of human cancers. | H zur Hausen | Biochim Biophys Acta | 1996 | 8876633 | No |
2199 | 2094 | 1047.0 | 57.03 | 28.5 | Microenvironmental regulation of metastasis. | Johanna A Joyce, Jeffrey W Pollard | Nat Rev Cancer | 2009 | 19279573 | No |
2200 | 2093 | 1046.5 | 39.36 | 19.7 | The DNA damage response: putting checkpoints in perspective. | B B Zhou, S J Elledge | Nature | 2000 | 11100718 | No |
2201 | 2093 | 1046.5 | 43.83 | 21.9 | A general framework for weighted gene co-expression network analysis. | Bin Zhang, Steve Horvath | Stat Appl Genet Mol Biol | 2005 | 16646834 | Yes |
2202 | 2092 | 1046.0 | 0.0 | 0.0 | A general method for isolation of high molecular weight DNA from eukaryotes. | N Blin, D W Stafford | Nucleic Acids Res | 1976 | 987581 | Yes |
2203 | 1046 | 1046.0 | 49.4 | 49.4 | Social phobia. | M R Liebowitz | Mod Probl Pharmacopsychiatry | 1987 | 2885745 | Yes |
2204 | 2092 | 1046.0 | 60.64 | 30.3 | Therapeutic potential of resveratrol: the in vivo evidence. | Joseph A Baur, David A Sinclair | Nat Rev Drug Discov | 2006 | 16732220 | No |
2205 | 1046 | 1046.0 | 32.86 | 32.9 | Stress and depression. | Constance Hammen | Annu Rev Clin Psychol | 2005 | 17716090 | No |
2206 | 1046 | 1046.0 | 0.0 | 0.0 | CRYSTALLINE SOYBEAN TRYPSIN INHIBITOR : II. GENERAL PROPERTIES. | M Kunitz | J Gen Physiol | 1947 | 19873496 | Yes |
2207 | 1045 | 1045.0 | 68.26 | 68.3 | Subjective well-being. | E Diener | Psychol Bull | 1984 | 6399758 | No |
2208 | 1045 | 1045.0 | 86.84 | 86.8 | The three column spine and its significance in the classification of acute thoracolumbar spinal injuries. | F Denis | Spine (Phila Pa 1976) | 1983 | 6670016 | Yes |
2209 | 1045 | 1045.0 | 21.72 | 21.7 | Protein kinases--the major drug targets of the twenty-first century? | Philip Cohen | Nat Rev Drug Discov | 2002 | 12120282 | No |
2210 | 1045 | 1045.0 | 0.0 | 0.0 | Note on the sampling error of the difference between correlated proportions or percentages. | Q McNEMAR | Psychometrika | 1947 | 20254758 | Yes |
2211 | 1044 | 1044.0 | 34.19 | 34.2 | Cell and environment interactions in tumor microregions: the multicell spheroid model. | R M Sutherland | Science | 1988 | 2451290 | Yes |
2212 | 1044 | 1044.0 | 26.45 | 26.4 | Double identity for proteins of the Bcl-2 family. | J C Reed | Nature | 1997 | 9194558 | No |
2213 | 1044 | 1044.0 | 25.43 | 25.4 | The Unified Medical Language System (UMLS): integrating biomedical terminology. | Olivier Bodenreider | Nucleic Acids Res | 2004 | 14681409 | Yes |
2214 | 1044 | 1044.0 | 24.84 | 24.8 | Recognition and processing of ubiquitin-protein conjugates by the proteasome. | Daniel Finley | Annu Rev Biochem | 2009 | 19489727 | No |
2215 | 1043 | 1043.0 | 30.52 | 30.5 | The hydrogen bond in the solid state. | Thomas Steiner | Angew Chem Int Ed Engl | 2002 | 12491444 | Yes |
2216 | 3129 | 1043.0 | 85.67 | 28.6 | Wnt/beta-catenin signaling: components, mechanisms, and diseases. | Bryan T MacDonald, Keiko Tamai, Xi He | Dev Cell | 2009 | 19619488 | No |
2217 | 1042 | 1042.0 | 24.33 | 24.3 | Caspase structure, proteolytic substrates, and function during apoptotic cell death. | D W Nicholson | Cell Death Differ | 1999 | 10578171 | No |
2218 | 1042 | 1042.0 | 25.82 | 25.8 | The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes. | S E Kahn | Diabetologia | 2003 | 12637977 | No |
2219 | 2084 | 1042.0 | 59.15 | 29.6 | Powering the planet: chemical challenges in solar energy utilization. | Nathan S Lewis, Daniel G Nocera | Proc Natl Acad Sci U S A | 2006 | 17043226 | Yes |
2220 | 9369 | 1041.0 | 372.71 | 41.4 | The 1982 revised criteria for the classification of systemic lupus erythematosus. | E M Tan, A S Cohen, J F Fries, A T Masi, D J McShane, N F Rothfield, J G Schaller, N Talal, R J Winchester | Arthritis Rheum | 1982 | 7138600 | Yes |
2221 | 3121 | 1040.3 | 125.29 | 41.8 | Factor structure of the Barratt impulsiveness scale. | J H Patton, M S Stanford, E S Barratt | J Clin Psychol | 1995 | 8778124 | Yes |
2222 | 1040 | 1040.0 | 33.37 | 33.4 | Current source-density method and application in cat cerebral cortex: investigation of evoked potentials and EEG phenomena. | U Mitzdorf | Physiol Rev | 1985 | 3880898 | No |
2223 | 1040 | 1040.0 | 0.0 | 0.0 | The origin of the genetic code. | F H Crick | J Mol Biol | 1968 | 4887876 | Yes |
2224 | 4159 | 1039.8 | 98.23 | 24.6 | Interleukin-10 and the interleukin-10 receptor. | K W Moore, R de Waal Malefyt, R L Coffman, A O'Garra | Annu Rev Immunol | 2001 | 11244051 | No |
2225 | 6237 | 1039.5 | 161.8 | 27.0 | Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. | Hadi Valadi, Karin Ekström, Apostolos Bossios, Margareta Sjöstrand, James J Lee, Jan O Lötvall | Nat Cell Biol | 2007 | 17486113 | Yes |
2226 | 1039 | 1039.0 | 0.0 | 0.0 | Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis. | K S McCully | Am J Pathol | 1969 | 5792556 | Yes |
2227 | 1039 | 1039.0 | 51.07 | 51.1 | Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture. | A H Conney | Cancer Res | 1982 | 6814745 | No |
2228 | 2078 | 1039.0 | 45.87 | 22.9 | Molecular chaperones in the cytosol: from nascent chain to folded protein. | F Ulrich Hartl, Manajit Hayer-Hartl | Science | 2002 | 11884745 | No |
2229 | 1039 | 1039.0 | 27.09 | 27.1 | Liver fibrosis -- from bench to bedside. | Scott L Friedman | J Hepatol | 2003 | 12591185 | No |
2230 | 1039 | 1039.0 | 30.87 | 30.9 | Q-ball imaging. | David S Tuch | Magn Reson Med | 2004 | 15562495 | Yes |
2231 | 1039 | 1039.0 | 38.03 | 38.0 | Gadolinium--a specific trigger for the development of nephrogenic fibrosing dermopathy and nephrogenic systemic fibrosis? | Thomas Grobner | Nephrol Dial Transplant | 2006 | 16431890 | Yes |
2232 | 2077 | 1038.5 | 63.6 | 31.8 | Meeting of minds: the medial frontal cortex and social cognition. | David M Amodio, Chris D Frith | Nat Rev Neurosci | 2006 | 16552413 | No |
2233 | 3115 | 1038.3 | 0.0 | 0.0 | A highly sensitive adenylate cyclase assay. | Y Salomon, C Londos, M Rodbell | Anal Biochem | 1974 | 4827395 | Yes |
2234 | 1038 | 1038.0 | 0.0 | 0.0 | Extraordinary sex ratios. A sex-ratio theory for sex linkage and inbreeding has new implications in cytogenetics and entomology. | W D Hamilton | Science | 1967 | 6021675 | Yes |
2235 | 1038 | 1038.0 | 31.87 | 31.9 | The aryl hydrocarbon receptor complex. | O Hankinson | Annu Rev Pharmacol Toxicol | 1995 | 7598497 | No |
2236 | 1038 | 1038.0 | 22.56 | 22.6 | Mechanisms of caspase activation and inhibition during apoptosis. | Yigong Shi | Mol Cell | 2002 | 11931755 | No |
2237 | 1038 | 1038.0 | 26.55 | 26.6 | Production of recombinant protein therapeutics in cultivated mammalian cells. | Florian M Wurm | Nat Biotechnol | 2004 | 15529164 | No |
2238 | 1038 | 1038.0 | 22.03 | 22.0 | IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. | Yong-Jun Liu | Annu Rev Immunol | 2005 | 15771572 | No |
2239 | 2076 | 1038.0 | 88.68 | 44.3 | How useful is SBF in predicting in vivo bone bioactivity? | Tadashi Kokubo, Hiroaki Takadama | Biomaterials | 2006 | 16448693 | No |
2240 | 2076 | 1038.0 | 60.4 | 30.2 | Improvement of phylogenies after removing divergent and ambiguously aligned blocks from protein sequence alignments. | Gerard Talavera, Jose Castresana | Syst Biol | 2007 | 17654362 | Yes |
2241 | 1038 | 1038.0 | 36.63 | 36.6 | Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. | Charles A Dinarello | Blood | 2011 | 21304099 | No |
2242 | 2075 | 1037.5 | 61.87 | 30.9 | Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. | Barry J Everitt, Trevor W Robbins | Nat Neurosci | 2005 | 16251991 | No |
2243 | 1037 | 1037.0 | 42.54 | 42.5 | Glycosphingolipids in cellular interaction, differentiation, and oncogenesis. | S Hakomori | Annu Rev Biochem | 1981 | 7023369 | No |
2244 | 2074 | 1037.0 | 60.92 | 30.5 | Rising incidence of hepatocellular carcinoma in the United States. | H B El-Serag, A C Mason | N Engl J Med | 1999 | 10072408 | Yes |
2245 | 1037 | 1037.0 | 25.91 | 25.9 | S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles. | R Donato | Int J Biochem Cell Biol | 2001 | 11390274 | No |
2246 | 1037 | 1037.0 | 25.65 | 25.6 | Molecular physiology of low-voltage-activated t-type calcium channels. | Edward Perez-Reyes | Physiol Rev | 2003 | 12506128 | No |
2247 | 1037 | 1037.0 | 22.34 | 22.3 | Lipid rafts: elusive or illusive? | Sean Munro | Cell | 2003 | 14622593 | No |
2248 | 1037 | 1037.0 | 24.05 | 24.1 | Solving structures of protein complexes by molecular replacement with Phaser. | Airlie J McCoy | Acta Crystallogr D Biol Crystallogr | 2007 | 17164524 | Yes |
2249 | 5183 | 1036.6 | 100.93 | 20.2 | Crystal structure of the nucleosome core particle at 2.8 A resolution. | K Luger, A W Mäder, R K Richmond, D F Sargent, T J Richmond | Nature | 1997 | 9305837 | Yes |
2250 | 2073 | 1036.5 | 60.75 | 30.4 | ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins. | Markus Wiederstein, Manfred J Sippl | Nucleic Acids Res | 2007 | 17517781 | Yes |
2251 | 1036 | 1036.0 | 0.0 | 0.0 | The carbon dioxide hydration activity of carbonic anhydrase. I. Stop-flow kinetic studies on the native human isoenzymes B and C. | R G Khalifah | J Biol Chem | 1971 | 4994926 | Yes |
2252 | 1036 | 1036.0 | 64.12 | 64.1 | Adjustments to Zatsiorsky-Seluyanov's segment inertia parameters. | P de Leva | J Biomech | 1996 | 8872282 | Yes |
2253 | 1036 | 1036.0 | 33.5 | 33.5 | Plant productivity and environment. | J S Boyer | Science | 1982 | 17808529 | Yes |
2254 | 2071 | 1035.5 | 74.35 | 37.2 | Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins. | D Marion, K Wüthrich | Biochem Biophys Res Commun | 1983 | 6307308 | Yes |
2255 | 1035 | 1035.0 | 35.25 | 35.2 | Rheumatoid arthritis. Pathophysiology and implications for therapy. | E D Harris | N Engl J Med | 1990 | 2271017 | No |
2256 | 1035 | 1035.0 | 40.07 | 40.1 | Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy. | A E Pegg | Cancer Res | 1988 | 3123052 | No |
2257 | 1035 | 1035.0 | 0.0 | 0.0 | Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate. | J W Olney | Science | 1969 | 5778021 | Yes |
2258 | 2070 | 1035.0 | 66.72 | 33.4 | Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA. | C Auffray, F Rougeon | Eur J Biochem | 1980 | 6772444 | Yes |
2259 | 1035 | 1035.0 | 19.25 | 19.2 | Cancer susceptibility and the functions of BRCA1 and BRCA2. | Ashok R Venkitaraman | Cell | 2002 | 11832208 | No |
2260 | 1035 | 1035.0 | 25.8 | 25.8 | Nuclear factor-kappaB: the enemy within. | Bharat B Aggarwal | Cancer Cell | 2004 | 15380510 | No |
2261 | 3104 | 1034.7 | 123.52 | 41.2 | Rehospitalizations among patients in the Medicare fee-for-service program. | Stephen F Jencks, Mark V Williams, Eric A Coleman | N Engl J Med | 2009 | 19339721 | Yes |
2262 | 1034 | 1034.0 | 32.24 | 32.2 | Internal models for motor control and trajectory planning. | M Kawato | Curr Opin Neurobiol | 1999 | 10607637 | No |
2263 | 1034 | 1034.0 | 0.0 | 0.0 | On the law of effect. | R J Herrnstein | J Exp Anal Behav | 1970 | 16811440 | Yes |
2264 | 2067 | 1033.5 | 59.03 | 29.5 | The free radical theory of aging matures. | K B Beckman, B N Ames | Physiol Rev | 1998 | 9562038 | No |
2265 | 1033 | 1033.0 | 38.12 | 38.1 | Classification of chronic viral hepatitis: a need for reassessment. | P J Scheuer | J Hepatol | 1991 | 1808228 | No |
2266 | 2066 | 1033.0 | 56.6 | 28.3 | Integrins and signal transduction pathways: the road taken. | E A Clark, J S Brugge | Science | 1995 | 7716514 | No |
2267 | 1032 | 1032.0 | 0.0 | 0.0 | Anterior acromioplasty for the chronic impingement syndrome in the shoulder: a preliminary report. | C S Neer | J Bone Joint Surg Am | 1972 | 5054450 | Yes |
2268 | 1032 | 1032.0 | 39.34 | 39.3 | Pathogenetic mechanisms of septic shock. | J E Parrillo | N Engl J Med | 1993 | 8479467 | No |
2269 | 5160 | 1032.0 | 242.6 | 48.5 | Evidence based medicine: what it is and what it isn't. | D L Sackett, W M Rosenberg, J A Gray, R B Haynes, W S Richardson | BMJ | 1996 | 8555924 | No |
2270 | 1032 | 1032.0 | 39.38 | 39.4 | An application of prefrontal cortex function theory to cognitive aging. | R L West | Psychol Bull | 1996 | 8831298 | No |
2271 | 1032 | 1032.0 | 43.38 | 43.4 | Inhibition and facilitation of nucleic acid amplification. | I G Wilson | Appl Environ Microbiol | 1997 | 9327537 | No |
2272 | 3096 | 1032.0 | 68.59 | 22.9 | Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM). | Michael J Rust, Mark Bates, Xiaowei Zhuang | Nat Methods | 2006 | 16896339 | Yes |
2273 | 1032 | 1032.0 | 36.31 | 36.3 | Endometriosis. | Serdar E Bulun | N Engl J Med | 2009 | 19144942 | No |
2274 | 2062 | 1031.0 | 73.1 | 36.5 | Quality control and preprocessing of metagenomic datasets. | Robert Schmieder, Robert Edwards | Bioinformatics | 2011 | 21278185 | Yes |
2275 | 3090 | 1030.0 | 80.96 | 27.0 | Tissue cells feel and respond to the stiffness of their substrate. | Dennis E Discher, Paul Janmey, Yu-Li Wang | Science | 2005 | 16293750 | No |
2276 | 2059 | 1029.5 | 83.93 | 42.0 | The framing of decisions and the psychology of choice. | A Tversky, D Kahneman | Science | 1981 | 7455683 | Yes |
2277 | 2058 | 1029.0 | 53.47 | 26.7 | Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis. | M Fried, D M Crothers | Nucleic Acids Res | 1981 | 6275366 | Yes |
2278 | 1029 | 1029.0 | 20.82 | 20.8 | A microRNA as a translational repressor of APETALA2 in Arabidopsis flower development. | Xuemei Chen | Science | 2004 | 12893888 | Yes |
2279 | 1029 | 1029.0 | 23.54 | 23.5 | The roles of intracellular protein-degradation pathways in neurodegeneration. | David C Rubinsztein | Nature | 2006 | 17051204 | No |
2280 | 1028 | 1028.0 | 0.0 | 0.0 | Atherogenesis: a postprandial phenomenon. | D B Zilversmit | Circulation | 1979 | 222498 | Yes |
2281 | 1028 | 1028.0 | 32.11 | 32.1 | Neural simulation of action: a unifying mechanism for motor cognition. | M Jeannerod | Neuroimage | 2001 | 11373140 | No |
2282 | 6160 | 1026.7 | 126.3 | 21.1 | Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. | S M Elbashir, J Harborth, W Lendeckel, A Yalcin, K Weber, T Tuschl | Nature | 2001 | 11373684 | Yes |
2283 | 2053 | 1026.5 | 80.09 | 40.0 | Oxidative mechanisms in the toxicity of metal ions. | S J Stohs, D Bagchi | Free Radic Biol Med | 1995 | 7744317 | No |
2284 | 1026 | 1026.0 | 31.35 | 31.4 | VLA proteins in the integrin family: structures, functions, and their role on leukocytes. | M E Hemler | Annu Rev Immunol | 1990 | 2188667 | No |
2285 | 1026 | 1026.0 | 33.99 | 34.0 | Type I diabetes mellitus. A chronic autoimmune disease. | G S Eisenbarth | N Engl J Med | 1986 | 3517648 | No |
2286 | 2052 | 1026.0 | 48.25 | 24.1 | CpG islands in vertebrate genomes. | M Gardiner-Garden, M Frommer | J Mol Biol | 1987 | 3656447 | Yes |
2287 | 1026 | 1026.0 | 0.0 | 0.0 | The organization of proteins in the human red blood cell membrane. A review. | T L Steck | J Cell Biol | 1974 | 4600883 | No |
2288 | 1026 | 1026.0 | 38.15 | 38.1 | The Neuropsychiatric Inventory: assessing psychopathology in dementia patients. | J L Cummings | Neurology | 1997 | 9153155 | No |
2289 | 2052 | 1026.0 | 40.89 | 20.4 | The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. | T Maehama, J E Dixon | J Biol Chem | 1998 | 9593664 | Yes |
2290 | 1026 | 1026.0 | 30.94 | 30.9 | Chronic mild stress (CMS) revisited: consistency and behavioural-neurobiological concordance in the effects of CMS. | Paul Willner | Neuropsychobiology | 2005 | 16037678 | No |
2291 | 1026 | 1026.0 | 39.59 | 39.6 | Cross-dehydrogenative coupling (CDC): exploring C-C bond formations beyond functional group transformations. | Chao-Jun Li | Acc Chem Res | 2009 | 19220064 | Yes |
2292 | 1025 | 1025.0 | 26.45 | 26.4 | Physiological and molecular basis of thyroid hormone action. | P M Yen | Physiol Rev | 2001 | 11427693 | No |
2293 | 3074 | 1024.7 | 83.62 | 27.9 | Global and societal implications of the diabetes epidemic. | P Zimmet, K G Alberti, J Shaw | Nature | 2001 | 11742409 | No |
2294 | 3073 | 1024.3 | 104.93 | 35.0 | Dose translation from animal to human studies revisited. | Shannon Reagan-Shaw, Minakshi Nihal, Nihal Ahmad | FASEB J | 2008 | 17942826 | Yes |
2295 | 1024 | 1024.0 | 36.01 | 36.0 | A Wilcoxon-type test for trend. | J Cuzick | Stat Med | 1985 | 3992076 | Yes |
2296 | 1024 | 1024.0 | 0.0 | 0.0 | The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept. | A G Pearse | J Histochem Cytochem | 1969 | 4143745 | No |
2297 | 1024 | 1024.0 | 37.3 | 37.3 | Depression in late life: review and commentary. | Dan G Blazer | J Gerontol A Biol Sci Med Sci | 2003 | 12634292 | No |
2298 | 2048 | 1024.0 | 0.0 | 0.0 | Mutants of Escherichia coli requiring methionine or vitamin B12. | B D DAVIS, E S MINGIOLI | J Bacteriol | 1950 | 15436457 | Yes |
2299 | 1024 | 1024.0 | 54.45 | 54.5 | Screening for lung cancer: U.S. Preventive Services Task Force recommendation statement. | Virginia A Moyer | Ann Intern Med | 2014 | 24378917 | No |
2300 | 4094 | 1023.5 | 117.97 | 29.5 | Microbial ecology: human gut microbes associated with obesity. | Ruth E Ley, Peter J Turnbaugh, Samuel Klein, Jeffrey I Gordon | Nature | 2006 | 17183309 | Yes |
2301 | 3070 | 1023.3 | 98.82 | 32.9 | Nitric oxide and peroxynitrite in health and disease. | Pál Pacher, Joseph S Beckman, Lucas Liaudet | Physiol Rev | 2007 | 17237348 | No |
2302 | 1023 | 1023.0 | 0.0 | 0.0 | Superoxide dismutases. | I Fridovich | Annu Rev Biochem | 1975 | 1094908 | No |
2303 | 1023 | 1023.0 | 54.13 | 54.1 | The self-medication hypothesis of addictive disorders: focus on heroin and cocaine dependence. | E J Khantzian | Am J Psychiatry | 1985 | 3904487 | No |
2304 | 1023 | 1023.0 | 0.0 | 0.0 | An enzymic method for the trace iodination of immunoglobulins and other proteins. | J J Marchalonis | Biochem J | 1969 | 4185494 | Yes |
2305 | 1023 | 1023.0 | 46.68 | 46.7 | UCLA Loneliness Scale (Version 3): reliability, validity, and factor structure. | D W Russell | J Pers Assess | 1996 | 8576833 | Yes |
2306 | 1023 | 1023.0 | 28.98 | 29.0 | The neuropathology of schizophrenia. A critical review of the data and their interpretation. | P J Harrison | Brain | 1999 | 10219775 | No |
2307 | 2046 | 1023.0 | 64.75 | 32.4 | Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. | Robert E W Hancock, Hans-Georg Sahl | Nat Biotechnol | 2006 | 17160061 | No |
2308 | 2045 | 1022.5 | 0.0 | 0.0 | Assay of proteins in the presence of interfering materials. | A Bensadoun, D Weinstein | Anal Biochem | 1976 | 1259145 | Yes |
2309 | 1022 | 1022.0 | 30.17 | 30.2 | Surrogate endpoints in clinical trials: definition and operational criteria. | R L Prentice | Stat Med | 1989 | 2727467 | Yes |
2310 | 1022 | 1022.0 | 20.19 | 20.2 | Kinesin and dynein superfamily proteins and the mechanism of organelle transport. | N Hirokawa | Science | 1998 | 9438838 | No |
2311 | 2043 | 1021.5 | 64.03 | 32.0 | The cognitive control of emotion. | Kevin N Ochsner, James J Gross | Trends Cogn Sci | 2005 | 15866151 | No |
2312 | 2042 | 1021.0 | 0.0 | 0.0 | Prediction of protein conformation. | P Y Chou, G D Fasman | Biochemistry | 1974 | 4358940 | Yes |
2313 | 2042 | 1021.0 | 66.09 | 33.0 | A review of central 5-HT receptors and their function. | N M Barnes, T Sharp | Neuropharmacology | 1999 | 10462127 | No |
2314 | 2042 | 1021.0 | 66.16 | 33.1 | Antibiotic resistance of bacteria in biofilms. | P S Stewart, J W Costerton | Lancet | 2001 | 11463434 | No |
2315 | 2041 | 1020.5 | 58.21 | 29.1 | Myocardial reperfusion injury. | Derek M Yellon, Derek J Hausenloy | N Engl J Med | 2007 | 17855673 | No |
2316 | 2040 | 1020.0 | 0.0 | 0.0 | Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. | D B Dill, D L Costill | J Appl Physiol | 1974 | 4850854 | Yes |
2317 | 1020 | 1020.0 | 0.0 | 0.0 | Defective repair replication of DNA in xeroderma pigmentosum. | J E Cleaver | Nature | 1968 | 5655953 | Yes |
2318 | 2040 | 1020.0 | 62.58 | 31.3 | Alternative activation of macrophages: mechanism and functions. | Siamon Gordon, Fernando O Martinez | Immunity | 2010 | 20510870 | No |
2319 | 2039 | 1019.5 | 133.0 | 66.5 | Research diagnostic criteria for temporomandibular disorders: review, criteria, examinations and specifications, critique. | S F Dworkin, L LeResche | J Craniomandib Disord | 1992 | 1298767 | No |
2320 | 2037 | 1018.5 | 62.94 | 31.5 | Imaging cognition II: An empirical review of 275 PET and fMRI studies. | R Cabeza, L Nyberg | J Cogn Neurosci | 2000 | 10769304 | No |
2321 | 1018 | 1018.0 | 70.13 | 70.1 | The tension-stress effect on the genesis and growth of tissues. Part I. The influence of stability of fixation and soft-tissue preservation. | G A Ilizarov | Clin Orthop Relat Res | 1989 | 2910611 | Yes |
2322 | 3054 | 1018.0 | 135.09 | 45.0 | Structure-antioxidant activity relationships of flavonoids and phenolic acids. | C A Rice-Evans, N J Miller, G Paganga | Free Radic Biol Med | 1996 | 8743980 | Yes |
2323 | 3052 | 1017.3 | 64.17 | 21.4 | The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. | Fabio Martinon, Kimberly Burns, Jürg Tschopp | Mol Cell | 2002 | 12191486 | Yes |
2324 | 1017 | 1017.0 | 0.0 | 0.0 | Metabolic stability and epigenesis in randomly constructed genetic nets. | S A Kauffman | J Theor Biol | 1969 | 5803332 | Yes |
2325 | 1017 | 1017.0 | 25.12 | 25.1 | Neurobiology of Pavlovian fear conditioning. | S Maren | Annu Rev Neurosci | 2001 | 11520922 | No |
2326 | 1017 | 1017.0 | 0.0 | 0.0 | The estimation of phosphorus. | R J Allen | Biochem J | 1940 | 16747230 | Yes |
2327 | 1016 | 1016.0 | 27.75 | 27.8 | Matrix proteoglycans: from molecular design to cellular function. | R V Iozzo | Annu Rev Biochem | 1998 | 9759499 | No |
2328 | 2032 | 1016.0 | 48.27 | 24.1 | Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. | Eugenia E Calle, Rudolf Kaaks | Nat Rev Cancer | 2004 | 15286738 | No |
2329 | 1016 | 1016.0 | 31.34 | 31.3 | How brains beware: neural mechanisms of emotional attention. | Patrik Vuilleumier | Trends Cogn Sci | 2005 | 16289871 | Yes |
2330 | 2031 | 1015.5 | 50.13 | 25.1 | Adaptive protein evolution at the Adh locus in Drosophila. | J H McDonald, M Kreitman | Nature | 1991 | 1904993 | Yes |
2331 | 1015 | 1015.0 | 33.54 | 33.5 | The induction of pain: an integrative review. | M J Millan | Prog Neurobiol | 1999 | 9987804 | No |
2332 | 1015 | 1015.0 | 23.27 | 23.3 | Gene finding in novel genomes. | Ian Korf | BMC Bioinformatics | 2004 | 15144565 | Yes |
2333 | 1015 | 1015.0 | 36.55 | 36.5 | The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. | Artemis P Simopoulos | Exp Biol Med (Maywood) | 2008 | 18408140 | No |
2334 | 4059 | 1014.8 | 170.46 | 42.6 | Prevalence and trends in obesity among US adults, 1999-2008. | Katherine M Flegal, Margaret D Carroll, Cynthia L Ogden, Lester R Curtin | JAMA | 2010 | 20071471 | Yes |
2335 | 2029 | 1014.5 | 65.72 | 32.9 | Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule. | M D Pierschbacher, E Ruoslahti | Nature | 1984 | 6325925 | Yes |
2336 | 1014 | 1014.0 | 48.5 | 48.5 | Translating social ecological theory into guidelines for community health promotion. | D Stokols | Am J Health Promot | 1996 | 10159709 | No |
2337 | 3041 | 1013.7 | 68.6 | 22.9 | Cellular survival: a play in three Akts. | S R Datta, A Brunet, M E Greenberg | Genes Dev | 1999 | 10579998 | No |
2338 | 2027 | 1013.5 | 59.09 | 29.5 | Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients. | S Schulman, C Kearon | J Thromb Haemost | 2005 | 15842354 | Yes |
2339 | 1013 | 1013.0 | 23.42 | 23.4 | STATs: signal transducers and activators of transcription. | J N Ihle | Cell | 1996 | 8608586 | No |
2340 | 1013 | 1013.0 | 35.53 | 35.5 | Invasive aspergillosis. | D W Denning | Clin Infect Dis | 1998 | 9564455 | No |
2341 | 1013 | 1013.0 | 26.34 | 26.3 | Mitochondrial transport of cations: channels, exchangers, and permeability transition. | P Bernardi | Physiol Rev | 1999 | 10508231 | No |
2342 | 3039 | 1013.0 | 80.59 | 26.9 | Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides. | Christian W Tornøe, Caspar Christensen, Morten Meldal | J Org Chem | 2002 | 11975567 | Yes |
2343 | 1013 | 1013.0 | 32.74 | 32.7 | Emotion regulation: affective, cognitive, and social consequences. | James J Gross | Psychophysiology | 2002 | 12212647 | No |
2344 | 1013 | 1013.0 | 50.61 | 50.6 | KDIGO clinical practice guidelines for acute kidney injury. | Arif Khwaja | Nephron Clin Pract | 2012 | 22890468 | No |
2345 | 2025 | 1012.5 | 79.61 | 39.8 | The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. | W R Gibb, A J Lees | J Neurol Neurosurg Psychiatry | 1988 | 2841426 | No |
2346 | 1012 | 1012.0 | 26.39 | 26.4 | Oxidative stress in neurodegeneration: cause or consequence? | Julie K Andersen | Nat Med | 2004 | 15298006 | No |
2347 | 2023 | 1011.5 | 78.74 | 39.4 | Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. | J E Hixson, D T Vernier | J Lipid Res | 1990 | 2341813 | Yes |
2348 | 2023 | 1011.5 | 100.53 | 50.3 | Reading senseless sentences: brain potentials reflect semantic incongruity. | M Kutas, S A Hillyard | Science | 1980 | 7350657 | Yes |
2349 | 3033 | 1011.0 | 0.0 | 0.0 | Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins. | J Garnier, D J Osguthorpe, B Robson | J Mol Biol | 1978 | 642007 | Yes |
2350 | 1011 | 1011.0 | 22.79 | 22.8 | Morphogenetic roles of classic cadherins. | M Takeichi | Curr Opin Cell Biol | 1995 | 8573335 | No |
2351 | 3033 | 1011.0 | 69.76 | 23.3 | Toll-like receptors: critical proteins linking innate and acquired immunity. | S Akira, K Takeda, T Kaisho | Nat Immunol | 2001 | 11477402 | No |
2352 | 1011 | 1011.0 | 26.55 | 26.6 | Huntington's disease. | Francis O Walker | Lancet | 2007 | 17240289 | No |
2353 | 2021 | 1010.5 | 96.57 | 48.3 | Malondialdehyde determination as index of lipid peroxidation. | H H Draper, M Hadley | Methods Enzymol | 1990 | 2233309 | Yes |
2354 | 1010 | 1010.0 | 0.0 | 0.0 | Optimal foraging, the marginal value theorem. | E L Charnov | Theor Popul Biol | 1976 | 1273796 | Yes |
2355 | 3030 | 1010.0 | 0.0 | 0.0 | Improved method for the determination of blood glutathione. | E BEUTLER, O DURON, B M KELLY | J Lab Clin Med | 1963 | 13967893 | Yes |
2356 | 1010 | 1010.0 | 29.32 | 29.3 | Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. | G L Semenza | Oncogene | 2010 | 19946328 | No |
2357 | 2018 | 1009.0 | 54.11 | 27.1 | The codon Adaptation Index--a measure of directional synonymous codon usage bias, and its potential applications. | P M Sharp, W H Li | Nucleic Acids Res | 1987 | 3547335 | Yes |
2358 | 1009 | 1009.0 | 42.93 | 42.9 | Multimodal approach to control postoperative pathophysiology and rehabilitation. | H Kehlet | Br J Anaesth | 1997 | 9175983 | No |
2359 | 2018 | 1009.0 | 64.46 | 32.2 | Increasing incidence of thyroid cancer in the United States, 1973-2002. | Louise Davies, H Gilbert Welch | JAMA | 2006 | 16684987 | Yes |
2360 | 3027 | 1009.0 | 85.98 | 28.7 | Membrane lipids: where they are and how they behave. | Gerrit van Meer, Dennis R Voelker, Gerald W Feigenson | Nat Rev Mol Cell Biol | 2008 | 18216768 | No |
2361 | 1009 | 1009.0 | 24.56 | 24.6 | Human natural killer cells. | Michael A Caligiuri | Blood | 2008 | 18650461 | No |
2362 | 3022 | 1007.3 | 111.28 | 37.1 | Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. | S van der Linden, H A Valkenburg, A Cats | Arthritis Rheum | 1984 | 6231933 | Yes |
2363 | 1007 | 1007.0 | 24.51 | 24.5 | Microglia as a source and target of cytokines. | Uwe-Karsten Hanisch | Glia | 2002 | 12379902 | No |
2364 | 2014 | 1007.0 | 45.65 | 22.8 | The mammalian unfolded protein response. | Martin Schröder, Randal J Kaufman | Annu Rev Biochem | 2005 | 15952902 | No |
2365 | 1007 | 1007.0 | 25.61 | 25.6 | The impact of next-generation sequencing technology on genetics. | Elaine R Mardis | Trends Genet | 2008 | 18262675 | No |
2366 | 1006 | 1006.0 | 33.29 | 33.3 | The molecular genetics of cancer. | J M Bishop | Science | 1987 | 3541204 | No |
2367 | 2012 | 1006.0 | 48.0 | 24.0 | Functions of lipid rafts in biological membranes. | D A Brown, E London | Annu Rev Cell Dev Biol | 1998 | 9891780 | No |
2368 | 1006 | 1006.0 | 23.09 | 23.1 | Assortative mixing in networks. | M E J Newman | Phys Rev Lett | 2002 | 12443515 | Yes |
2369 | 1006 | 1006.0 | 29.66 | 29.7 | Hydrogen sulphide and its therapeutic potential. | Csaba Szabó | Nat Rev Drug Discov | 2007 | 17948022 | No |
2370 | 4024 | 1006.0 | 105.59 | 26.4 | Autophagy fights disease through cellular self-digestion. | Noboru Mizushima, Beth Levine, Ana Maria Cuervo, Daniel J Klionsky | Nature | 2008 | 18305538 | No |
2371 | 1005 | 1005.0 | 42.83 | 42.8 | Hydrophilic-interaction chromatography for the separation of peptides, nucleic acids and other polar compounds. | A J Alpert | J Chromatogr | 1990 | 2324207 | Yes |
2372 | 1005 | 1005.0 | 45.78 | 45.8 | The life and times of the Enterococcus. | B E Murray | Clin Microbiol Rev | 1990 | 2404568 | No |
2373 | 2010 | 1005.0 | 53.6 | 26.8 | Peroxisome proliferator-activated receptors: nuclear control of metabolism. | B Desvergne, W Wahli | Endocr Rev | 1999 | 10529898 | No |
2374 | 2010 | 1005.0 | 47.1 | 23.6 | Toll-like receptors in the induction of the innate immune response. | A Aderem, R J Ulevitch | Nature | 2000 | 10963608 | No |
2375 | 1005 | 1005.0 | 34.18 | 34.2 | Cytokinesis-block micronucleus cytome assay. | Michael Fenech | Nat Protoc | 2007 | 17546000 | Yes |
2376 | 3014 | 1004.7 | 106.12 | 35.4 | The functional anatomy of basal ganglia disorders. | R L Albin, A B Young, J B Penney | Trends Neurosci | 1989 | 2479133 | No |
2377 | 2008 | 1004.0 | 0.0 | 0.0 | Social networks, host resistance, and mortality: a nine-year follow-up study of Alameda County residents. | L F Berkman, S L Syme | Am J Epidemiol | 1979 | 425958 | Yes |
2378 | 1004 | 1004.0 | 0.0 | 0.0 | Refinement of the coomassie blue method of protein quantitation. A simple and linear spectrophotometric assay for less than or equal to 0.5 to 50 microgram of protein. | T Spector | Anal Biochem | 1978 | 655375 | Yes |
2379 | 1004 | 1004.0 | 31.39 | 31.4 | Normalization of cell responses in cat striate cortex. | D J Heeger | Vis Neurosci | 1992 | 1504027 | Yes |
2380 | 2008 | 1004.0 | 156.3 | 78.2 | A joint coordinate system for the clinical description of three-dimensional motions: application to the knee. | E S Grood, W J Suntay | J Biomech Eng | 1983 | 6865355 | Yes |
2381 | 1004 | 1004.0 | 26.33 | 26.3 | Ordered porous materials for emerging applications. | Mark E Davis | Nature | 2002 | 12075343 | No |
2382 | 1004 | 1004.0 | 30.47 | 30.5 | Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome: a summary of the evidence. | Earl S Ford | Diabetes Care | 2005 | 15983333 | No |
2383 | 3012 | 1004.0 | 117.49 | 39.2 | Universal solvation model based on solute electron density and on a continuum model of the solvent defined by the bulk dielectric constant and atomic surface tensions. | Aleksandr V Marenich, Christopher J Cramer, Donald G Truhlar | J Phys Chem B | 2009 | 19366259 | Yes |
2384 | 1002 | 1002.0 | 82.21 | 82.2 | Impingement lesions. | C S Neer | Clin Orthop Relat Res | 1983 | 6825348 | Yes |
2385 | 1002 | 1002.0 | 25.86 | 25.9 | The prefrontal cortex and cognitive control. | E K Miller | Nat Rev Neurosci | 2000 | 11252769 | No |
2386 | 1002 | 1002.0 | 29.41 | 29.4 | Neural systems for recognizing emotion. | Ralph Adolphs | Curr Opin Neurobiol | 2002 | 12015233 | No |
2387 | 1002 | 1002.0 | 27.39 | 27.4 | Non-Smad pathways in TGF-beta signaling. | Ying E Zhang | Cell Res | 2009 | 19114990 | No |
2388 | 1002 | 1002.0 | 51.25 | 51.2 | Selenium and human health. | Margaret P Rayman | Lancet | 2012 | 22381456 | No |
2389 | 2003 | 1001.5 | 38.38 | 19.2 | Hedgehog signaling in animal development: paradigms and principles. | P W Ingham, A P McMahon | Genes Dev | 2001 | 11731473 | No |
2390 | 2002 | 1001.0 | 74.75 | 37.4 | Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. | J I Morgan, T Curran | Annu Rev Neurosci | 1991 | 1903243 | No |
2391 | 3003 | 1001.0 | 132.22 | 44.1 | Vascular endothelial cells synthesize nitric oxide from L-arginine. | R M Palmer, D S Ashton, S Moncada | Nature | 1988 | 3131684 | Yes |
2392 | 2002 | 1001.0 | 45.27 | 22.6 | Tumorigenesis and the angiogenic switch. | Gabriele Bergers, Laura E Benjamin | Nat Rev Cancer | 2003 | 12778130 | No |
2393 | 2001 | 1000.5 | 37.86 | 18.9 | Stats: transcriptional control and biological impact. | David E Levy, J E Darnell | Nat Rev Mol Cell Biol | 2002 | 12209125 | No |
2394 | 2001 | 1000.5 | 49.2 | 24.6 | Can the pharmaceutical industry reduce attrition rates? | Ismail Kola, John Landis | Nat Rev Drug Discov | 2004 | 15286737 | No |
2395 | 1000 | 1000.0 | 35.59 | 35.6 | Early signals in the mitogenic response. | E Rozengurt | Science | 1986 | 3018928 | No |
2396 | 2000 | 1000.0 | 47.55 | 23.8 | T-cell antigen receptor genes and T-cell recognition. | M M Davis, P J Bjorkman | Nature | 1988 | 3043226 | No |
2397 | 1000 | 1000.0 | 30.53 | 30.5 | Physiology and pathophysiology of purinergic neurotransmission. | Geoffrey Burnstock | Physiol Rev | 2007 | 17429044 | No |
2398 | 1999 | 999.5 | 128.67 | 64.3 | A study of the natural history of back pain. Part I: development of a reliable and sensitive measure of disability in low-back pain. | M Roland, R Morris | Spine (Phila Pa 1976) | 1983 | 6222486 | Yes |
2399 | 1999 | 999.5 | 42.41 | 21.2 | NF-kappaB at the crossroads of life and death. | Michael Karin, Anning Lin | Nat Immunol | 2002 | 11875461 | No |
2400 | 1999 | 999.5 | 53.32 | 26.7 | Raster3D Version 2.0. A program for photorealistic molecular graphics. | E A Merritt, M E Murphy | Acta Crystallogr D Biol Crystallogr | 1994 | 15299354 | Yes |
2401 | 999 | 999.0 | 18.57 | 18.6 | Stem cells: units of development, units of regeneration, and units in evolution. | I L Weissman | Cell | 2000 | 10647940 | No |
2402 | 999 | 999.0 | 31.61 | 31.6 | Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective. | Antoine Bechara | Nat Neurosci | 2005 | 16251988 | No |
2403 | 998 | 998.0 | 21.94 | 21.9 | Cytokines induce the development of functionally heterogeneous T helper cell subsets. | A O'Garra | Immunity | 1998 | 9529145 | No |
2404 | 998 | 998.0 | 28.82 | 28.8 | Somatostatin and its receptor family. | Y C Patel | Front Neuroendocrinol | 1999 | 10433861 | No |
2405 | 1996 | 998.0 | 49.27 | 24.6 | Toll-like receptors in innate immunity. | Kiyoshi Takeda, Shizuo Akira | Int Immunol | 2005 | 15585605 | No |
2406 | 998 | 998.0 | 29.54 | 29.5 | Plasmonics: merging photonics and electronics at nanoscale dimensions. | Ekmel Ozbay | Science | 2006 | 16410515 | Yes |
2407 | 1995 | 997.5 | 0.0 | 0.0 | Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma. | G Blobel, B Dobberstein | J Cell Biol | 1975 | 811671 | Yes |
2408 | 997 | 997.0 | 86.49 | 86.5 | The problem of rigor in qualitative research. | M Sandelowski | ANS Adv Nurs Sci | 1986 | 3083765 | Yes |
2409 | 996 | 996.0 | 39.67 | 39.7 | Risk and maintenance factors for eating pathology: a meta-analytic review. | Eric Stice | Psychol Bull | 2002 | 12206196 | No |
2410 | 1991 | 995.5 | 45.27 | 22.6 | NF-kappaB: linking inflammation and immunity to cancer development and progression. | Michael Karin, Florian R Greten | Nat Rev Immunol | 2005 | 16175180 | No |
2411 | 3981 | 995.2 | 0.0 | 0.0 | Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. | D W Cleveland, S G Fischer, M W Kirschner, U K Laemmli | J Biol Chem | 1977 | 320200 | Yes |
2412 | 995 | 995.0 | 35.31 | 35.3 | Diversity of group types, regulation, and function of phospholipase A2. | E A Dennis | J Biol Chem | 1994 | 8175726 | No |
2413 | 995 | 995.0 | 32.15 | 32.1 | Low density lipoprotein oxidation and its pathobiological significance. | D Steinberg | J Biol Chem | 1997 | 9261091 | No |
2414 | 995 | 995.0 | 0.0 | 0.0 | ANTIGEN-ANTIBODY CROSSED ELECTROPHORESIS. | C B LAURELL | Anal Biochem | 1965 | 14302464 | Yes |
2415 | 995 | 995.0 | 23.54 | 23.5 | Version 1.2 of the Crystallography and NMR system. | Axel T Brunger | Nat Protoc | 2007 | 18007608 | Yes |
2416 | 994 | 994.0 | 0.0 | 0.0 | Reversible binding of Pi by beef heart mitochondrial adenosine triphosphatase. | H S Penefsky | J Biol Chem | 1977 | 16006 | Yes |
2417 | 1988 | 994.0 | 0.0 | 0.0 | Glutathione peroxidase activity in selenium-deficient rat liver. | R A Lawrence, R F Burk | Biochem Biophys Res Commun | 1976 | 971321 | Yes |
2418 | 994 | 994.0 | 34.32 | 34.3 | Analyzing the mosaic structure of genes. | J M Smith | J Mol Evol | 1992 | 1556748 | No |
2419 | 994 | 994.0 | 44.56 | 44.6 | Quantitative methods in the review of epidemiologic literature. | S Greenland | Epidemiol Rev | 1987 | 3678409 | Yes |
2420 | 3976 | 994.0 | 113.82 | 28.5 | Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. | H Nielsen, J Engelbrecht, S Brunak, G von Heijne | Protein Eng | 1997 | 9051728 | Yes |
2421 | 994 | 994.0 | 25.84 | 25.8 | Diarylethenes for Memories and Switches. | Masahiro Irie | Chem Rev | 2000 | 11777416 | Yes |
2422 | 1988 | 994.0 | 61.03 | 30.5 | A neurotrophic model for stress-related mood disorders. | Ronald S Duman, Lisa M Monteggia | Biol Psychiatry | 2006 | 16631126 | No |
2423 | 994 | 994.0 | 29.02 | 29.0 | Mitochondrial fusion and fission in cell life and death. | Benedikt Westermann | Nat Rev Mol Cell Biol | 2010 | 21102612 | No |
2424 | 6954 | 993.4 | 355.61 | 50.8 | Development and validation of a geriatric depression screening scale: a preliminary report. | J A Yesavage, T L Brink, T L Rose, O Lum, V Huang, M Adey, V O Leirer | J Psychiatr Res | 1982 | 7183759 | Yes |
2425 | 993 | 993.0 | 33.82 | 33.8 | Tumor necrosis factor (TNF). | L J Old | Science | 1985 | 2413547 | Yes |
2426 | 1986 | 993.0 | 64.8 | 32.4 | Production of single-stranded plasmid DNA. | J Vieira, J Messing | Methods Enzymol | 1987 | 3323803 | Yes |
2427 | 1986 | 993.0 | 63.85 | 31.9 | Epidemiology and outcomes of osteoporotic fractures. | Steven R Cummings, L Joseph Melton | Lancet | 2002 | 12049882 | No |
2428 | 1985 | 992.5 | 47.38 | 23.7 | The canonical Notch signaling pathway: unfolding the activation mechanism. | Raphael Kopan, Maria Xenia G Ilagan | Cell | 2009 | 19379690 | No |
2429 | 1985 | 992.5 | 87.81 | 43.9 | Neutrophil recruitment and function in health and inflammation. | Elzbieta Kolaczkowska, Paul Kubes | Nat Rev Immunol | 2013 | 23435331 | No |
2430 | 2977 | 992.3 | 109.06 | 36.4 | MR diffusion tensor spectroscopy and imaging. | P J Basser, J Mattiello, D LeBihan | Biophys J | 1994 | 8130344 | Yes |
2431 | 10914 | 992.2 | 421.75 | 38.3 | A new equation to estimate glomerular filtration rate. | Andrew S Levey, Lesley A Stevens, Christopher H Schmid, Yaping Lucy Zhang, Alejandro F Castro, Harold I Feldman, John W Kusek, Paul Eggers, Frederick Van Lente, Tom Greene, Josef Coresh | Ann Intern Med | 2009 | 19414839 | Yes |
2432 | 2976 | 992.0 | 178.78 | 59.6 | In search of how people change. Applications to addictive behaviors. | J O Prochaska, C C DiClemente, J C Norcross | Am Psychol | 1992 | 1329589 | Yes |
2433 | 992 | 992.0 | 50.67 | 50.7 | A cochlear frequency-position function for several species--29 years later. | D D Greenwood | J Acoust Soc Am | 1990 | 2373794 | Yes |
2434 | 992 | 992.0 | 17.27 | 17.3 | Mitotic kinases as regulators of cell division and its checkpoints. | E A Nigg | Nat Rev Mol Cell Biol | 2001 | 11413462 | No |
2435 | 991 | 991.0 | 44.45 | 44.5 | Lyme disease. | A C Steere | N Engl J Med | 1989 | 2668764 | No |
2436 | 991 | 991.0 | 0.0 | 0.0 | The intraclass correlation coefficient as a measure of reliability. | J J Bartko | Psychol Rep | 1966 | 5942109 | Yes |
2437 | 991 | 991.0 | 26.19 | 26.2 | Metastatic bone disease: clinical features, pathophysiology and treatment strategies. | R E Coleman | Cancer Treat Rev | 2001 | 11417967 | No |
2438 | 1982 | 991.0 | 0.0 | 0.0 | The effect of sodium ions on the electrical activity of giant axon of the squid. | A L HODGKIN, B KATZ | J Physiol | 1949 | 18128147 | Yes |
2439 | 1981 | 990.5 | 56.75 | 28.4 | Statistical tests of neutrality of mutations. | Y X Fu, W H Li | Genetics | 1993 | 8454210 | Yes |
2440 | 1981 | 990.5 | 0.0 | 0.0 | A new scale of social desirability independent of psychopathology. | D P CROWNE, D MARLOWE | J Consult Psychol | 1960 | 13813058 | Yes |
2441 | 1981 | 990.5 | 95.83 | 47.9 | The M1 and M2 paradigm of macrophage activation: time for reassessment. | Fernando O Martinez, Siamon Gordon | F1000Prime Rep | 2014 | 24669294 | No |
2442 | 1980 | 990.0 | 68.34 | 34.2 | Analysis of gene control signals by DNA fusion and cloning in Escherichia coli. | M J Casadaban, S N Cohen | J Mol Biol | 1980 | 6997493 | Yes |
2443 | 990 | 990.0 | 24.62 | 24.6 | Next-generation DNA sequencing methods. | Elaine R Mardis | Annu Rev Genomics Hum Genet | 2008 | 18576944 | No |
2444 | 1979 | 989.5 | 71.37 | 35.7 | An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. | O Johnell, J A Kanis | Osteoporos Int | 2006 | 16983459 | Yes |
2445 | 989 | 989.0 | 24.87 | 24.9 | Estimating absolute rates of molecular evolution and divergence times: a penalized likelihood approach. | Michael J Sanderson | Mol Biol Evol | 2002 | 11752195 | Yes |
2446 | 989 | 989.0 | 37.43 | 37.4 | Socioeconomic status and obesity. | Lindsay McLaren | Epidemiol Rev | 2007 | 17478442 | No |
2447 | 2966 | 988.7 | 84.65 | 28.2 | LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions. | A C Wallace, R A Laskowski, J M Thornton | Protein Eng | 1995 | 7630882 | Yes |
2448 | 1975 | 987.5 | 0.0 | 0.0 | Maximum utilization of the life table method in analyzing survival. | S J CUTLER, F EDERER | J Chronic Dis | 1958 | 13598782 | Yes |
2449 | 2962 | 987.3 | 98.32 | 32.8 | Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. | Günter Oberdörster, Eva Oberdörster, Jan Oberdörster | Environ Health Perspect | 2005 | 16002369 | No |
2450 | 1974 | 987.0 | 46.29 | 23.1 | Sequence logos: a new way to display consensus sequences. | T D Schneider, R M Stephens | Nucleic Acids Res | 1990 | 2172928 | Yes |
2451 | 1973 | 986.5 | 69.79 | 34.9 | A cognitive model of posttraumatic stress disorder. | A Ehlers, D M Clark | Behav Res Ther | 2000 | 10761279 | No |
2452 | 1973 | 986.5 | 40.63 | 20.3 | Rho GTPases: biochemistry and biology. | Aron B Jaffe, Alan Hall | Annu Rev Cell Dev Biol | 2005 | 16212495 | No |
2453 | 986 | 986.0 | 22.49 | 22.5 | Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. | Harold F Dvorak | J Clin Oncol | 2002 | 12409337 | No |
2454 | 2957 | 985.7 | 101.56 | 33.9 | Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. | H King, R E Aubert, W H Herman | Diabetes Care | 1998 | 9727886 | Yes |
2455 | 3941 | 985.2 | 101.41 | 25.4 | SCOP: a structural classification of proteins database for the investigation of sequences and structures. | A G Murzin, S E Brenner, T Hubbard, C Chothia | J Mol Biol | 1995 | 7723011 | Yes |
2456 | 985 | 985.0 | 32.78 | 32.8 | Phylogenies from molecular sequences: inference and reliability. | J Felsenstein | Annu Rev Genet | 1988 | 3071258 | No |
2457 | 985 | 985.0 | 0.0 | 0.0 | The measurement of psychological androgyny. | S L Bem | J Consult Clin Psychol | 1974 | 4823550 | Yes |
2458 | 985 | 985.0 | 44.19 | 44.2 | Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes. | M A Lemp | CLAO J | 1995 | 8565190 | No |
2459 | 985 | 985.0 | 34.99 | 35.0 | The structure of common mental disorders. | R F Krueger | Arch Gen Psychiatry | 1999 | 10530634 | Yes |
2460 | 985 | 985.0 | 27.66 | 27.7 | Metabolism and functions of glutathione in brain. | R Dringen | Prog Neurobiol | 2000 | 10880854 | No |
2461 | 985 | 985.0 | 20.36 | 20.4 | Regulation of phosphoinositide-specific phospholipase C. | S G Rhee | Annu Rev Biochem | 2001 | 11395409 | No |
2462 | 985 | 985.0 | 39.18 | 39.2 | The epidemiology of adult obstructive sleep apnea. | Naresh M Punjabi | Proc Am Thorac Soc | 2008 | 18250205 | No |
2463 | 984 | 984.0 | 25.65 | 25.6 | The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. | G B Morin | Cell | 1989 | 2805070 | Yes |
2464 | 1968 | 984.0 | 63.3 | 31.6 | Supercoil sequencing: a fast and simple method for sequencing plasmid DNA. | E Y Chen, P H Seeburg | DNA | 1985 | 3996185 | Yes |
2465 | 984 | 984.0 | 0.0 | 0.0 | Drugs which inhibit prostaglandin biosynthesis. | R J Flower | Pharmacol Rev | 1974 | 4208101 | Yes |
2466 | 984 | 984.0 | 0.0 | 0.0 | A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon. | A M Olovnikov | J Theor Biol | 1973 | 4754905 | Yes |
2467 | 984 | 984.0 | 0.0 | 0.0 | Autoradiographic and histological studies of postnatal neurogenesis. IV. Cell proliferation and migration in the anterior forebrain, with special reference to persisting neurogenesis in the olfactory bulb. | J Altman | J Comp Neurol | 1969 | 5361244 | Yes |
2468 | 984 | 984.0 | 25.12 | 25.1 | Heterotrimeric G proteins: organizers of transmembrane signals. | E J Neer | Cell | 1995 | 7834744 | No |
2469 | 984 | 984.0 | 23.3 | 23.3 | Stem cells in the central nervous system. | R McKay | Science | 1997 | 9082987 | No |
2470 | 984 | 984.0 | 20.37 | 20.4 | Microarray data normalization and transformation. | John Quackenbush | Nat Genet | 2002 | 12454644 | No |
2471 | 984 | 984.0 | 34.81 | 34.8 | Mitochondria and cancer. | Douglas C Wallace | Nat Rev Cancer | 2012 | 23001348 | No |
2472 | 5903 | 983.8 | 161.22 | 26.9 | GROMACS: fast, flexible, and free. | David Van Der Spoel, Erik Lindahl, Berk Hess, Gerrit Groenhof, Alan E Mark, Herman J C Berendsen | J Comput Chem | 2005 | 16211538 | Yes |
2473 | 983 | 983.0 | 28.22 | 28.2 | Molecular themes in oncogenesis. | J M Bishop | Cell | 1991 | 1988146 | No |
2474 | 2947 | 982.3 | 85.13 | 28.4 | Dystrophin: the protein product of the Duchenne muscular dystrophy locus. | E P Hoffman, R H Brown, L M Kunkel | Cell | 1987 | 3319190 | Yes |
2475 | 1964 | 982.0 | 100.3 | 50.1 | Numerical index of the discriminatory ability of typing systems: an application of Simpson's index of diversity. | P R Hunter, M A Gaston | J Clin Microbiol | 1988 | 3069867 | Yes |
2476 | 982 | 982.0 | 0.0 | 0.0 | A comparison of canal preparations in straight and curved root canals. | S W Schneider | Oral Surg Oral Med Oral Pathol | 1971 | 5284110 | Yes |
2477 | 982 | 982.0 | 46.09 | 46.1 | Assessing self-maintenance: activities of daily living, mobility, and instrumental activities of daily living. | S Katz | J Am Geriatr Soc | 1983 | 6418786 | No |
2478 | 982 | 982.0 | 34.1 | 34.1 | Modeling tracer kinetics in dynamic Gd-DTPA MR imaging. | P S Tofts | J Magn Reson Imaging | 1997 | 9039598 | No |
2479 | 15710 | 981.9 | 622.01 | 38.9 | Fiji: an open-source platform for biological-image analysis. | Johannes Schindelin, Ignacio Arganda-Carreras, Erwin Frise, Verena Kaynig, Mark Longair, Tobias Pietzsch, Stephan Preibisch, Curtis Rueden, Stephan Saalfeld, Benjamin Schmid, Jean-Yves Tinevez, Daniel James White, Volker Hartenstein, Kevin Eliceiri, Pavel Tomancak, Albert Cardona | Nat Methods | 2012 | 22743772 | Yes |
2480 | 3926 | 981.5 | 121.75 | 30.4 | Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. | Michael J Pencina, Ralph B D'Agostino, Ralph B D'Agostino, Ramachandran S Vasan | Stat Med | 2008 | 17569110 | Yes |
2481 | 981 | 981.0 | 29.64 | 29.6 | The lipocalin protein family: structure and function. | D R Flower | Biochem J | 1996 | 8761444 | No |
2482 | 1962 | 981.0 | 43.24 | 21.6 | Plant pathogens and integrated defence responses to infection. | J L Dangl, J D Jones | Nature | 2001 | 11459065 | No |
2483 | 981 | 981.0 | 31.91 | 31.9 | The biochemistry and medical significance of the flavonoids. | Bent H Havsteen | Pharmacol Ther | 2002 | 12453566 | No |
2484 | 981 | 981.0 | 33.88 | 33.9 | High prevalence of vitamin D inadequacy and implications for health. | Michael F Holick | Mayo Clin Proc | 2006 | 16529140 | No |
2485 | 981 | 981.0 | 22.05 | 22.1 | Evo-devo and an expanding evolutionary synthesis: a genetic theory of morphological evolution. | Sean B Carroll | Cell | 2008 | 18614008 | Yes |
2486 | 1961 | 980.5 | 45.78 | 22.9 | Atherosclerosis. the road ahead. | C K Glass, J L Witztum | Cell | 2001 | 11239408 | No |
2487 | 980 | 980.0 | 26.15 | 26.1 | Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration. | T A Springer | Annu Rev Physiol | 1995 | 7778885 | No |
2488 | 980 | 980.0 | 23.19 | 23.2 | Physiological concentrations of purines and pyrimidines. | T W Traut | Mol Cell Biochem | 1994 | 7877593 | No |
2489 | 980 | 980.0 | 22.35 | 22.4 | Chromosomal translocations in human cancer. | T H Rabbitts | Nature | 1994 | 7969446 | No |
2490 | 980 | 980.0 | 26.14 | 26.1 | Allelic discrimination using fluorogenic probes and the 5' nuclease assay. | K J Livak | Genet Anal | 1999 | 10084106 | Yes |
2491 | 980 | 980.0 | 25.71 | 25.7 | Plant salt tolerance. | J K Zhu | Trends Plant Sci | 2001 | 11173290 | Yes |
2492 | 1960 | 980.0 | 48.85 | 24.4 | Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. | Jing Yang, Robert A Weinberg | Dev Cell | 2008 | 18539112 | No |
2493 | 980 | 980.0 | 39.34 | 39.3 | The amazing osteocyte. | Lynda F Bonewald | J Bone Miner Res | 2011 | 21254230 | No |
2494 | 1959 | 979.5 | 50.37 | 25.2 | Long short-term memory. | S Hochreiter, J Schmidhuber | Neural Comput | 1997 | 9377276 | Yes |
2495 | 1959 | 979.5 | 61.32 | 30.7 | Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. | Ajay Kumar Gupta, Mona Gupta | Biomaterials | 2005 | 15626447 | No |
2496 | 1959 | 979.5 | 46.27 | 23.1 | Defining the role of mTOR in cancer. | David A Guertin, David M Sabatini | Cancer Cell | 2007 | 17613433 | No |
2497 | 979 | 979.0 | 49.56 | 49.6 | Cardiac valve surgery--the "French correction". | A Carpentier | J Thorac Cardiovasc Surg | 1983 | 6887954 | Yes |
2498 | 979 | 979.0 | 25.59 | 25.6 | Brain tumors. | L M DeAngelis | N Engl J Med | 2001 | 11150363 | No |
2499 | 1958 | 979.0 | 48.81 | 24.4 | Escaping free-energy minima. | Alessandro Laio, Michele Parrinello | Proc Natl Acad Sci U S A | 2002 | 12271136 | Yes |
2500 | 979 | 979.0 | 26.11 | 26.1 | Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis. | R Balfour Sartor | Nat Clin Pract Gastroenterol Hepatol | 2006 | 16819502 | No |
2501 | 979 | 979.0 | 34.29 | 34.3 | Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles. | Felix Kratz | J Control Release | 2008 | 18582981 | No |
2502 | 1958 | 979.0 | 50.1 | 25.1 | Next-generation DNA sequencing. | Jay Shendure, Hanlee Ji | Nat Biotechnol | 2008 | 18846087 | Yes |
2503 | 3915 | 978.8 | 140.54 | 35.1 | Place navigation impaired in rats with hippocampal lesions. | R G Morris, P Garrud, J N Rawlins, J O'Keefe | Nature | 1982 | 7088155 | Yes |
2504 | 978 | 978.0 | 0.0 | 0.0 | Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors. | J C Unkeless | J Exp Med | 1979 | 90108 | Yes |
2505 | 1956 | 978.0 | 48.66 | 24.3 | A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. | N C Andrews, D V Faller | Nucleic Acids Res | 1991 | 2041787 | Yes |
2506 | 978 | 978.0 | 34.39 | 34.4 | Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes. | W Sieghart | Pharmacol Rev | 1995 | 7568326 | No |
2507 | 1955 | 977.5 | 0.0 | 0.0 | Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. | G J TODARO, H GREEN | J Cell Biol | 1963 | 13985244 | Yes |
2508 | 977 | 977.0 | 52.72 | 52.7 | Human agency in social cognitive theory. | A Bandura | Am Psychol | 1989 | 2782727 | Yes |
2509 | 977 | 977.0 | 59.25 | 59.2 | Derivation and validation of a short-form oral health impact profile. | G D Slade | Community Dent Oral Epidemiol | 1997 | 9332805 | Yes |
2510 | 977 | 977.0 | 36.71 | 36.7 | Delirium in older persons. | Sharon K Inouye | N Engl J Med | 2006 | 16540616 | No |
2511 | 977 | 977.0 | 25.76 | 25.8 | Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. | Hiroshi Takayanagi | Nat Rev Immunol | 2007 | 17380158 | No |
2512 | 2930 | 976.7 | 73.93 | 24.6 | Hepatocellular carcinoma. | Josep M Llovet, Andrew Burroughs, Jordi Bruix | Lancet | 2003 | 14667750 | No |
2513 | 1952 | 976.0 | 62.77 | 31.4 | Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. | R G Phillips, J E LeDoux | Behav Neurosci | 1992 | 1590953 | Yes |
2514 | 1952 | 976.0 | 50.89 | 25.4 | Emerging roles of caspase-3 in apoptosis. | A G Porter, R U Jänicke | Cell Death Differ | 1999 | 10200555 | No |
2515 | 976 | 976.0 | 25.56 | 25.6 | Evaluating medication effects outside of clinical trials: new-user designs. | Wayne A Ray | Am J Epidemiol | 2003 | 14585769 | Yes |
2516 | 976 | 976.0 | 28.34 | 28.3 | Wound healing and its impairment in the diabetic foot. | Vincent Falanga | Lancet | 2005 | 16291068 | No |
2517 | 975 | 975.0 | 46.33 | 46.3 | Multiple calcium channels and neuronal function. | R J Miller | Science | 1987 | 2432656 | No |
2518 | 975 | 975.0 | 33.35 | 33.4 | Seminars in medicine of the Beth Israel Hospital, Boston. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies. | S L Friedman | N Engl J Med | 1993 | 8502273 | No |
2519 | 975 | 975.0 | 26.31 | 26.3 | Oxyradicals and DNA damage. | L J Marnett | Carcinogenesis | 2000 | 10688856 | No |
2520 | 975 | 975.0 | 21.15 | 21.1 | Inferences, questions and possibilities in Toll-like receptor signalling. | Bruce Beutler | Nature | 2004 | 15241424 | No |
2521 | 1948 | 974.0 | 0.0 | 0.0 | Selective loss of central cholinergic neurons in Alzheimer's disease. | P Davies, A J Maloney | Lancet | 1976 | 63862 | Yes |
2522 | 974 | 974.0 | 18.66 | 18.7 | The development of neural stem cells. | S Temple | Nature | 2001 | 11689956 | No |
2523 | 2921 | 973.7 | 66.36 | 22.1 | Adjusting batch effects in microarray expression data using empirical Bayes methods. | W Evan Johnson, Cheng Li, Ariel Rabinovic | Biostatistics | 2007 | 16632515 | Yes |
2524 | 1946 | 973.0 | 0.0 | 0.0 | Radiological demarcation of cemented sockets in total hip replacement. | J G DeLee, J Charnley | Clin Orthop Relat Res | 1976 | 991504 | Yes |
2525 | 973 | 973.0 | 35.19 | 35.2 | Recent developments in isocyanide based multicomponent reactions in applied chemistry. | Alexander Dömling | Chem Rev | 2006 | 16402771 | No |
2526 | 2919 | 973.0 | 75.45 | 25.2 | Evolution and functions of long noncoding RNAs. | Chris P Ponting, Peter L Oliver, Wolf Reik | Cell | 2009 | 19239885 | No |
2527 | 4863 | 972.6 | 0.0 | 0.0 | Transection of the oesophagus for bleeding oesophageal varices. | R N Pugh, I M Murray-Lyon, J L Dawson, M C Pietroni, R Williams | Br J Surg | 1973 | 4541913 | Yes |
2528 | 1945 | 972.5 | 92.54 | 46.3 | The N1 wave of the human electric and magnetic response to sound: a review and an analysis of the component structure. | R Näätänen, T Picton | Psychophysiology | 1987 | 3615753 | Yes |
2529 | 972 | 972.0 | 42.19 | 42.2 | The LMS method for constructing normalized growth standards. | T J Cole | Eur J Clin Nutr | 1990 | 2354692 | Yes |
2530 | 972 | 972.0 | 63.46 | 63.5 | The determinants of parenting: a process model. | J Belsky | Child Dev | 1984 | 6705636 | Yes |
2531 | 972 | 972.0 | 29.42 | 29.4 | The basic science of gene therapy. | R C Mulligan | Science | 1993 | 8493530 | No |
2532 | 2915 | 971.7 | 64.77 | 21.6 | Large-scale analysis of the yeast proteome by multidimensional protein identification technology. | M P Washburn, D Wolters, J R Yates | Nat Biotechnol | 2001 | 11231557 | Yes |
2533 | 971 | 971.0 | 24.27 | 24.3 | Large Amplitude Elastic Motions in Proteins from a Single-Parameter, Atomic Analysis. | Tirion | Phys Rev Lett | 1996 | 10063201 | Yes |
2534 | 1942 | 971.0 | 49.62 | 24.8 | Quorum sensing in bacteria. | M B Miller, B L Bassler | Annu Rev Microbiol | 2001 | 11544353 | No |
2535 | 971 | 971.0 | 24.6 | 24.6 | Pedigree disequilibrium tests for multilocus haplotypes. | Frank Dudbridge | Genet Epidemiol | 2003 | 12916020 | Yes |
2536 | 971 | 971.0 | 0.0 | 0.0 | A personality scale of manifest anxiety. | J A TAYLOR | J Abnorm Psychol | 1953 | 13052352 | Yes |
2537 | 971 | 971.0 | 39.99 | 40.0 | Volumetric modulated arc therapy: IMRT in a single gantry arc. | Karl Otto | Med Phys | 2008 | 18293586 | Yes |
2538 | 2911 | 970.3 | 81.61 | 27.2 | Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm. | Y Zhang, M Brady, S Smith | IEEE Trans Med Imaging | 2001 | 11293691 | Yes |
2539 | 2911 | 970.3 | 116.28 | 38.8 | Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS. | B K Matuszewski, M L Constanzer, C M Chavez-Eng | Anal Chem | 2003 | 12964746 | Yes |
2540 | 1940 | 970.0 | 44.97 | 22.5 | Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. | C W Greider, E H Blackburn | Cell | 1985 | 3907856 | Yes |
2541 | 970 | 970.0 | 0.0 | 0.0 | Dopamine (3-hydroxytyramine) and brain function. | O Hornykiewicz | Pharmacol Rev | 1966 | 5328389 | No |
2542 | 970 | 970.0 | 19.5 | 19.5 | Histone-deacetylase inhibitors: novel drugs for the treatment of cancer. | Ricky W Johnstone | Nat Rev Drug Discov | 2002 | 12120280 | No |
2543 | 970 | 970.0 | 0.0 | 0.0 | The critical incident technique. | J C FLANAGAN | Psychol Bull | 1954 | 13177800 | Yes |
2544 | 970 | 970.0 | 0.0 | 0.0 | Intra-sexual selection in Drosophila. | A J BATEMAN | Heredity (Edinb) | 1948 | 18103134 | Yes |
2545 | 970 | 970.0 | 52.83 | 52.8 | Comments on 'KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease'. | Konrad M Andrassy | Kidney Int | 2013 | 23989362 | Yes |
2546 | 1939 | 969.5 | 58.1 | 29.1 | Nanostructures in biodiagnostics. | Nathaniel L Rosi, Chad A Mirkin | Chem Rev | 2005 | 15826019 | No |
2547 | 2907 | 969.0 | 67.29 | 22.4 | Predicting coiled coils from protein sequences. | A Lupas, M Van Dyke, J Stock | Science | 1991 | 2031185 | Yes |
2548 | 969 | 969.0 | 35.54 | 35.5 | The human immunodeficiency virus: infectivity and mechanisms of pathogenesis. | A S Fauci | Science | 1988 | 3277274 | No |
2549 | 969 | 969.0 | 35.83 | 35.8 | The aging process. | D Harman | Proc Natl Acad Sci U S A | 1981 | 6947277 | Yes |
2550 | 1938 | 969.0 | 0.0 | 0.0 | Histological grading and prognosis in breast cancer; a study of 1409 cases of which 359 have been followed for 15 years. | H J BLOOM, W W RICHARDSON | Br J Cancer | 1957 | 13499785 | Yes |
2551 | 969 | 969.0 | 20.3 | 20.3 | Regulation of cadherin-mediated adhesion in morphogenesis. | Barry M Gumbiner | Nat Rev Mol Cell Biol | 2005 | 16025097 | No |
2552 | 969 | 969.0 | 28.89 | 28.9 | Polymer conjugates as anticancer nanomedicines. | Ruth Duncan | Nat Rev Cancer | 2006 | 16900224 | No |
2553 | 2906 | 968.7 | 135.01 | 45.0 | Multiple imputation using chained equations: Issues and guidance for practice. | Ian R White, Patrick Royston, Angela M Wood | Stat Med | 2011 | 21225900 | Yes |
2554 | 3874 | 968.5 | 100.41 | 25.1 | A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes. | Vsevolod V Rostovtsev, Luke G Green, Valery V Fokin, K Barry Sharpless | Angew Chem Int Ed Engl | 2002 | 12203546 | Yes |
2555 | 1937 | 968.5 | 61.46 | 30.7 | Integrins in cancer: biological implications and therapeutic opportunities. | Jay S Desgrosellier, David A Cheresh | Nat Rev Cancer | 2010 | 20029421 | No |
2556 | 1936 | 968.0 | 84.72 | 42.4 | Total energy intake: implications for epidemiologic analyses. | W Willett, M J Stampfer | Am J Epidemiol | 1986 | 3521261 | No |
2557 | 2904 | 968.0 | 93.83 | 31.3 | Molecular characterization of a peripheral receptor for cannabinoids. | S Munro, K L Thomas, M Abu-Shaar | Nature | 1993 | 7689702 | Yes |
2558 | 968 | 968.0 | 30.28 | 30.3 | The neurobiology of stress: from serendipity to clinical relevance. | B S McEwen | Brain Res | 2000 | 11119695 | No |
2559 | 968 | 968.0 | 21.95 | 21.9 | Apoptosis in neurodegenerative disorders. | M P Mattson | Nat Rev Mol Cell Biol | 2000 | 11253364 | No |
2560 | 2903 | 967.7 | 123.32 | 41.1 | Hepatocellular carcinoma. | Alejandro Forner, Josep M Llovet, Jordi Bruix | Lancet | 2012 | 22353262 | No |
2561 | 967 | 967.0 | 0.0 | 0.0 | Bee and wasp venoms. | E Habermann | Science | 1972 | 4113805 | No |
2562 | 3868 | 967.0 | 82.7 | 20.7 | Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. | L Alexopoulou, A C Holt, R Medzhitov, R A Flavell | Nature | 2001 | 11607032 | Yes |
2563 | 967 | 967.0 | 22.94 | 22.9 | Platelets in atherothrombosis. | Zaverio M Ruggeri | Nat Med | 2002 | 12411949 | No |
2564 | 967 | 967.0 | 29.29 | 29.3 | Persister cells, dormancy and infectious disease. | Kim Lewis | Nat Rev Microbiol | 2007 | 17143318 | No |
2565 | 967 | 967.0 | 33.62 | 33.6 | Understanding organofluorine chemistry. An introduction to the C-F bond. | David O'Hagan | Chem Soc Rev | 2008 | 18197347 | No |
2566 | 967 | 967.0 | 61.02 | 61.0 | Computing Inter-Rater Reliability for Observational Data: An Overview and Tutorial. | Kevin A Hallgren | Tutor Quant Methods Psychol | 2012 | 22833776 | Yes |
2567 | 966 | 966.0 | 19.16 | 19.2 | Antigen receptor tail clue. | M Reth | Nature | 1989 | 2927501 | Yes |
2568 | 966 | 966.0 | 23.02 | 23.0 | Antigen-specific interaction between T and B cells. | A Lanzavecchia | Nature | 1985 | 3157869 | Yes |
2569 | 966 | 966.0 | 43.36 | 43.4 | Linkage map of Escherichia coli K-12, edition 7. | B J Bachmann | Microbiol Rev | 1983 | 6348505 | No |
2570 | 966 | 966.0 | 26.62 | 26.6 | Neurons with graded response have collective computational properties like those of two-state neurons. | J J Hopfield | Proc Natl Acad Sci U S A | 1984 | 6587342 | Yes |
2571 | 966 | 966.0 | 21.71 | 21.7 | Regulation of transcription by MAP kinase cascades. | R Treisman | Curr Opin Cell Biol | 1996 | 8791420 | No |
2572 | 966 | 966.0 | 21.07 | 21.1 | Mechanisms and consequences of activation of protein kinase B/Akt. | J Downward | Curr Opin Cell Biol | 1998 | 9561851 | No |
2573 | 966 | 966.0 | 21.46 | 21.5 | Basement membranes: structure, assembly and role in tumour angiogenesis. | Raghu Kalluri | Nat Rev Cancer | 2003 | 12778132 | No |
2574 | 1932 | 966.0 | 68.1 | 34.0 | Alternatives for logistic regression in cross-sectional studies: an empirical comparison of models that directly estimate the prevalence ratio. | Aluísio J D Barros, Vânia N Hirakata | BMC Med Res Methodol | 2003 | 14567763 | Yes |
2575 | 1931 | 965.5 | 69.18 | 34.6 | Chronic hepatitis B: update 2009. | Anna S F Lok, Brian J McMahon | Hepatology | 2009 | 19714720 | Yes |
2576 | 1930 | 965.0 | 46.92 | 23.5 | Synaptic activity and the construction of cortical circuits. | L C Katz, C J Shatz | Science | 1996 | 8895456 | No |
2577 | 965 | 965.0 | 31.16 | 31.2 | Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications. | P Lips | Endocr Rev | 2001 | 11493580 | No |
2578 | 965 | 965.0 | 18.62 | 18.6 | Biological robustness. | Hiroaki Kitano | Nat Rev Genet | 2004 | 15520792 | No |
2579 | 1928 | 964.0 | 54.26 | 27.1 | Drug delivery systems: entering the mainstream. | Theresa M Allen, Pieter R Cullis | Science | 2004 | 15031496 | Yes |
2580 | 1928 | 964.0 | 71.88 | 35.9 | Plasmonics for improved photovoltaic devices. | Harry A Atwater, Albert Polman | Nat Mater | 2010 | 20168344 | Yes |
2581 | 2891 | 963.7 | 80.65 | 26.9 | Functional diversity of helper T lymphocytes. | A K Abbas, K M Murphy, A Sher | Nature | 1996 | 8893001 | No |
2582 | 1927 | 963.5 | 75.95 | 38.0 | Intracellular pH. | A Roos, W F Boron | Physiol Rev | 1981 | 7012859 | No |
2583 | 1927 | 963.5 | 58.75 | 29.4 | Apoptosis, oncosis, and necrosis. An overview of cell death. | G Majno, I Joris | Am J Pathol | 1995 | 7856735 | No |
2584 | 2890 | 963.3 | 1445.0 | 481.7 | Cancer statistics, 2020. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2020 | 31912902 | Yes |
2585 | 1926 | 963.0 | 176.03 | 88.0 | Natural Products as Sources of New Drugs from 1981 to 2014. | David J Newman, Gordon M Cragg | J Nat Prod | 2016 | 26852623 | No |
2586 | 6737 | 962.4 | 273.71 | 39.1 | GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. | Gordon H Guyatt, Andrew D Oxman, Gunn E Vist, Regina Kunz, Yngve Falck-Ytter, Pablo Alonso-Coello, Holger J Schünemann | BMJ | 2008 | 18436948 | Yes |
2587 | 962 | 962.0 | 0.0 | 0.0 | A new readability yardstick. | R FLESCH | J Appl Psychol | 1948 | 18867058 | Yes |
2588 | 1923 | 961.5 | 68.88 | 34.4 | A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data. | A Ennaceur, J Delacour | Behav Brain Res | 1988 | 3228475 | Yes |
2589 | 961 | 961.0 | 19.73 | 19.7 | Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast. | R Rothstein | Methods Enzymol | 1991 | 2005793 | Yes |
2590 | 961 | 961.0 | 0.0 | 0.0 | Neuron-glia relationship during granule cell migration in developing cerebellar cortex. A Golgi and electronmicroscopic study in Macacus Rhesus. | P Rakic | J Comp Neurol | 1971 | 4101340 | Yes |
2591 | 961 | 961.0 | 19.81 | 19.8 | The power and the promise of DNA methylation markers. | Peter W Laird | Nat Rev Cancer | 2003 | 12671664 | No |
2592 | 961 | 961.0 | 30.91 | 30.9 | Infection in solid-organ transplant recipients. | Jay A Fishman | N Engl J Med | 2007 | 18094380 | No |
2593 | 961 | 961.0 | 34.15 | 34.1 | Persister cells. | Kim Lewis | Annu Rev Microbiol | 2010 | 20528688 | No |
2594 | 1922 | 961.0 | 67.77 | 33.9 | Accessories to the crime: functions of cells recruited to the tumor microenvironment. | Douglas Hanahan, Lisa M Coussens | Cancer Cell | 2012 | 22439926 | No |
2595 | 961 | 961.0 | 39.11 | 39.1 | The role of autophagy in neurodegenerative disease. | Ralph A Nixon | Nat Med | 2013 | 23921753 | No |
2596 | 960 | 960.0 | 42.42 | 42.4 | The theoretical bases of indirect calorimetry: a review. | E Ferrannini | Metabolism | 1988 | 3278194 | No |
2597 | 960 | 960.0 | 53.82 | 53.8 | Biomaterial-centered infection: microbial adhesion versus tissue integration. | A G Gristina | Science | 1987 | 3629258 | Yes |
2598 | 1920 | 960.0 | 70.73 | 35.4 | Mediation in experimental and nonexperimental studies: new procedures and recommendations. | Patrick E Shrout, Niall Bolger | Psychol Methods | 2002 | 12530702 | Yes |
2599 | 1920 | 960.0 | 58.55 | 29.3 | Biology of incretins: GLP-1 and GIP. | Laurie L Baggio, Daniel J Drucker | Gastroenterology | 2007 | 17498508 | No |
2600 | 8638 | 959.8 | 684.11 | 76.0 | Cancer statistics in China, 2015. | Wanqing Chen, Rongshou Zheng, Peter D Baade, Siwei Zhang, Hongmei Zeng, Freddie Bray, Ahmedin Jemal, Xue Qin Yu, Jie He | CA Cancer J Clin | 2016 | 26808342 | Yes |
2601 | 959 | 959.0 | 30.44 | 30.4 | Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis. | C Taswell | J Immunol | 1981 | 7009746 | Yes |
2602 | 959 | 959.0 | 17.4 | 17.4 | Molecular mechanisms of axon guidance. | Barry J Dickson | Science | 2002 | 12471249 | No |
2603 | 959 | 959.0 | 35.91 | 35.9 | Breakthrough of the year 2013. Cancer immunotherapy. | Jennifer Couzin-Frankel | Science | 2013 | 24357284 | No |
2604 | 958 | 958.0 | 0.0 | 0.0 | Nature of Col E 1 plasmid replication in Escherichia coli in the presence of the chloramphenicol. | D B Clewell | J Bacteriol | 1972 | 4336693 | Yes |
2605 | 1916 | 958.0 | 57.42 | 28.7 | Genetic dissection of complex traits. | E S Lander, N J Schork | Science | 1994 | 8091226 | No |
2606 | 958 | 958.0 | 32.26 | 32.3 | Papillary and follicular thyroid carcinoma. | M J Schlumberger | N Engl J Med | 1998 | 9445411 | No |
2607 | 958 | 958.0 | 21.37 | 21.4 | Protein tyrosine phosphatases: from genes, to function, to disease. | Nicholas K Tonks | Nat Rev Mol Cell Biol | 2006 | 17057753 | No |
2608 | 2869 | 956.3 | 86.55 | 28.8 | Bacterial biofilms: from the natural environment to infectious diseases. | Luanne Hall-Stoodley, J William Costerton, Paul Stoodley | Nat Rev Microbiol | 2004 | 15040259 | No |
2609 | 956 | 956.0 | 0.0 | 0.0 | RNA metabolism in the HeLa cell nucleus. | S Penman | J Mol Biol | 1966 | 5961144 | Yes |
2610 | 956 | 956.0 | 32.73 | 32.7 | Peptide antibiotics and their role in innate immunity. | H G Boman | Annu Rev Immunol | 1995 | 7612236 | No |
2611 | 956 | 956.0 | 23.52 | 23.5 | The myofibroblast in wound healing and fibrocontractive diseases. | G Gabbiani | J Pathol | 2003 | 12845617 | No |
2612 | 956 | 956.0 | 0.0 | 0.0 | A modified ninhydrin colorimetric analysis for amino acids. | H ROSEN | Arch Biochem Biophys | 1957 | 13412116 | Yes |
2613 | 1912 | 956.0 | 89.76 | 44.9 | Neoantigens in cancer immunotherapy. | Ton N Schumacher, Robert D Schreiber | Science | 2015 | 25838375 | No |
2614 | 1912 | 956.0 | 64.83 | 32.4 | The OPLS [optimized potentials for liquid simulations] potential functions for proteins, energy minimizations for crystals of cyclic peptides and crambin. | W L Jorgensen, J Tirado-Rives | J Am Chem Soc | 1988 | 27557051 | Yes |
2615 | 1911 | 955.5 | 43.73 | 21.9 | Breaking the diffraction resolution limit by stimulated emission: stimulated-emission-depletion fluorescence microscopy. | S W Hell, J Wichmann | Opt Lett | 1994 | 19844443 | Yes |
2616 | 955 | 955.0 | 32.97 | 33.0 | Energy contributions of volatile fatty acids from the gastrointestinal tract in various species. | E N Bergman | Physiol Rev | 1990 | 2181501 | No |
2617 | 955 | 955.0 | 31.69 | 31.7 | The fetal and infant origins of adult disease. | D J Barker | BMJ | 1990 | 2252919 | No |
2618 | 955 | 955.0 | 32.96 | 33.0 | The molten globule state as a clue for understanding the folding and cooperativity of globular-protein structure. | K Kuwajima | Proteins | 1989 | 2695928 | No |
2619 | 955 | 955.0 | 43.69 | 43.7 | The structure of beta-lactamases. | R P Ambler | Philos Trans R Soc Lond B Biol Sci | 1980 | 6109327 | Yes |
2620 | 955 | 955.0 | 53.48 | 53.5 | Free-radical mechanisms in tissue injury. | T F Slater | Biochem J | 1984 | 6383353 | No |
2621 | 955 | 955.0 | 33.66 | 33.7 | Inferring microstructural features and the physiological state of tissues from diffusion-weighted images. | P J Basser | NMR Biomed | 1995 | 8739270 | No |
2622 | 955 | 955.0 | 0.0 | 0.0 | LINKED FUNCTIONS AND RECIPROCAL EFFECTS IN HEMOGLOBIN: A SECOND LOOK. | J WYMAN | Adv Protein Chem | 1964 | 14268785 | No |
2623 | 955 | 955.0 | 49.52 | 49.5 | Working memory: theories, models, and controversies. | Alan Baddeley | Annu Rev Psychol | 2012 | 21961947 | No |
2624 | 1909 | 954.5 | 67.39 | 33.7 | Natural products as sources of new drugs over the last 25 years. | David J Newman, Gordon M Cragg | J Nat Prod | 2007 | 17309302 | No |
2625 | 954 | 954.0 | 28.97 | 29.0 | Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology. | E M Tan | Adv Immunol | 1989 | 2646863 | No |
2626 | 1908 | 954.0 | 0.0 | 0.0 | Method for the isolation of intact islets of Langerhans from the rat pancreas. | P E Lacy, M Kostianovsky | Diabetes | 1967 | 5333500 | Yes |
2627 | 954 | 954.0 | 33.18 | 33.2 | The somatic marker hypothesis and the possible functions of the prefrontal cortex. | A R Damasio | Philos Trans R Soc Lond B Biol Sci | 1996 | 8941953 | No |
2628 | 954 | 954.0 | 22.53 | 22.5 | Prediction of protein cellular attributes using pseudo-amino acid composition. | K C Chou | Proteins | 2001 | 11288174 | Yes |
2629 | 954 | 954.0 | 21.49 | 21.5 | Microsatellites: simple sequences with complex evolution. | Hans Ellegren | Nat Rev Genet | 2004 | 15153996 | No |
2630 | 1908 | 954.0 | 62.49 | 31.2 | Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. | Taro Kawai, Shizuo Akira | Immunity | 2011 | 21616434 | No |
2631 | 2860 | 953.3 | 55.52 | 18.5 | Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. | S Moreno, A Klar, P Nurse | Methods Enzymol | 1991 | 2005825 | Yes |
2632 | 953 | 953.0 | 46.21 | 46.2 | Biology of interleukin 1. | C A Dinarello | FASEB J | 1988 | 3277884 | No |
2633 | 953 | 953.0 | 46.47 | 46.5 | Neuropeptide Y: complete amino acid sequence of the brain peptide. | K Tatemoto | Proc Natl Acad Sci U S A | 1982 | 6957876 | Yes |
2634 | 953 | 953.0 | 22.67 | 22.7 | The finer things in X-ray diffraction data collection. | J W Pflugrath | Acta Crystallogr D Biol Crystallogr | 1999 | 10531521 | Yes |
2635 | 3812 | 953.0 | 168.46 | 42.1 | Guidelines for the process of cross-cultural adaptation of self-report measures. | D E Beaton, C Bombardier, F Guillemin, M B Ferraz | Spine (Phila Pa 1976) | 2000 | 11124735 | No |
2636 | 953 | 953.0 | 22.85 | 22.9 | The enzymes, regulation, and genetics of bile acid synthesis. | David W Russell | Annu Rev Biochem | 2003 | 12543708 | No |
2637 | 953 | 953.0 | 0.0 | 0.0 | On the Absorption of Fluids from the Connective Tissue Spaces. | E H Starling | J Physiol | 1896 | 16992325 | Yes |
2638 | 1905 | 952.5 | 0.0 | 0.0 | Surgical risk as related to time of intervention in the repair of intracranial aneurysms. | W E Hunt, R M Hess | J Neurosurg | 1968 | 5635959 | Yes |
2639 | 952 | 952.0 | 19.94 | 19.9 | Focal adhesion kinase: the first ten years. | J Thomas Parsons | J Cell Sci | 2003 | 12640026 | No |
2640 | 1903 | 951.5 | 53.35 | 26.7 | C-reactive protein: a critical update. | Mark B Pepys, Gideon M Hirschfield | J Clin Invest | 2003 | 12813013 | No |
2641 | 2854 | 951.3 | 85.34 | 28.4 | Methods in mammalian autophagy research. | Noboru Mizushima, Tamotsu Yoshimori, Beth Levine | Cell | 2010 | 20144757 | Yes |
2642 | 951 | 951.0 | 60.49 | 60.5 | Assessment of chronic pain. I. Aspects of the reliability and validity of the visual analogue scale. | Anna Maria Carlsson | Pain | 1983 | 6602967 | Yes |
2643 | 2851 | 950.3 | 69.65 | 23.2 | Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. | Axel Nimmerjahn, Frank Kirchhoff, Fritjof Helmchen | Science | 2005 | 15831717 | Yes |
2644 | 1898 | 949.0 | 65.96 | 33.0 | Recent advances in the phencyclidine model of schizophrenia. | D C Javitt, S R Zukin | Am J Psychiatry | 1991 | 1654746 | No |
2645 | 949 | 949.0 | 35.16 | 35.2 | Relations between the statistics of natural images and the response properties of cortical cells. | D J Field | J Opt Soc Am A | 1987 | 3430225 | Yes |
2646 | 949 | 949.0 | 48.55 | 48.5 | Analysis of radioligand binding experiments. A collection of computer programs for the IBM PC. | G A McPherson | J Pharmacol Methods | 1985 | 3840547 | Yes |
2647 | 1898 | 949.0 | 46.05 | 23.0 | Lymphocyte homing and homeostasis. | E C Butcher, L J Picker | Science | 1996 | 8600538 | No |
2648 | 949 | 949.0 | 40.04 | 40.0 | Checklists for improving rigour in qualitative research: a case of the tail wagging the dog? | R S Barbour | BMJ | 2001 | 11337448 | No |
2649 | 949 | 949.0 | 0.0 | 0.0 | A NEW WEIGHTING SYSTEM FOR MEAN SURFACE TEMPERATURE OF THE HUMAN BODY. | N L RAMANATHAN | J Appl Physiol | 1964 | 14173555 | Yes |
2650 | 949 | 949.0 | 20.99 | 21.0 | Liver regeneration: from myth to mechanism. | Rebecca Taub | Nat Rev Mol Cell Biol | 2004 | 15459664 | No |
2651 | 5692 | 948.7 | 187.99 | 31.3 | Cancer statistics, 2007. | Ahmedin Jemal, Rebecca Siegel, Elizabeth Ward, Taylor Murray, Jiaquan Xu, Michael J Thun | CA Cancer J Clin | 2007 | 17237035 | Yes |
2652 | 13274 | 948.1 | 318.98 | 22.8 | Crystallography & NMR system: A new software suite for macromolecular structure determination. | A T Brünger, P D Adams, G M Clore, W L DeLano, P Gros, R W Grosse-Kunstleve, J S Jiang, J Kuszewski, M Nilges, N S Pannu, R J Read, L M Rice, T Simonson, G L Warren | Acta Crystallogr D Biol Crystallogr | 1998 | 9757107 | Yes |
2653 | 948 | 948.0 | 0.0 | 0.0 | Experience from a multicentre stroke register: a preliminary report. | S Hatano | Bull World Health Organ | 1976 | 1088404 | Yes |
2654 | 948 | 948.0 | 32.88 | 32.9 | Deconvoluting the context-dependent role for autophagy in cancer. | Eileen White | Nat Rev Cancer | 2012 | 22534666 | No |
2655 | 1895 | 947.5 | 51.36 | 25.7 | Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival. | Josep M Llovet, Jordi Bruix | Hepatology | 2003 | 12540794 | No |
2656 | 947 | 947.0 | 23.38 | 23.4 | How neutrophils kill microbes. | Anthony W Segal | Annu Rev Immunol | 2005 | 15771570 | No |
2657 | 1893 | 946.5 | 64.33 | 32.2 | Nitric oxide synthases: roles, tolls, and controls. | C Nathan, Q W Xie | Cell | 1994 | 7522969 | No |
2658 | 1893 | 946.5 | 47.54 | 23.8 | Esophageal cancer. | Peter C Enzinger, Robert J Mayer | N Engl J Med | 2003 | 14657432 | No |
2659 | 1893 | 946.5 | 46.88 | 23.4 | Blinded by the Light: The Growing Complexity of p53. | Karen H Vousden, Carol Prives | Cell | 2009 | 19410540 | No |
2660 | 946 | 946.0 | 0.0 | 0.0 | Regulation of noradrenaline release by presynaptic receptor systems. | K Starke | Rev Physiol Biochem Pharmacol | 1977 | 14389 | No |
2661 | 946 | 946.0 | 20.83 | 20.8 | Likelihood ratio tests for detecting positive selection and application to primate lysozyme evolution. | Z Yang | Mol Biol Evol | 1998 | 9580986 | Yes |
2662 | 946 | 946.0 | 0.0 | 0.0 | Sequential tests for the detection of linkage. | N E MORTON | Am J Hum Genet | 1955 | 13258560 | Yes |
2663 | 4725 | 945.0 | 286.72 | 57.3 | Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. | N Bellamy, W W Buchanan, C H Goldsmith, J Campbell, L W Stitt | J Rheumatol | 1988 | 3068365 | Yes |
2664 | 3780 | 945.0 | 96.44 | 24.1 | Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. | G L Wang, B H Jiang, E A Rue, G L Semenza | Proc Natl Acad Sci U S A | 1995 | 7539918 | Yes |
2665 | 945 | 945.0 | 25.57 | 25.6 | Optical microcavities. | Kerry J Vahala | Nature | 2003 | 12917698 | Yes |
2666 | 945 | 945.0 | 0.0 | 0.0 | Cellular resistance to infection. | G B MACKANESS | J Exp Med | 1962 | 14467923 | Yes |
2667 | 3777 | 944.2 | 123.79 | 30.9 | Prevalence and trends in obesity among US adults, 1999-2000. | Katherine M Flegal, Margaret D Carroll, Cynthia L Ogden, Clifford L Johnson | JAMA | 2002 | 12365955 | Yes |
2668 | 1888 | 944.0 | 50.87 | 25.4 | Heat-shock proteins, molecular chaperones, and the stress response: evolutionary and ecological physiology. | M E Feder, G E Hofmann | Annu Rev Physiol | 1999 | 10099689 | No |
2669 | 944 | 944.0 | 21.6 | 21.6 | Phenotypic plasticity and the epigenetics of human disease. | Andrew P Feinberg | Nature | 2007 | 17522677 | No |
2670 | 1888 | 944.0 | 52.08 | 26.0 | Principles of bioactive lipid signalling: lessons from sphingolipids. | Yusuf A Hannun, Lina M Obeid | Nat Rev Mol Cell Biol | 2008 | 18216770 | No |
2671 | 1888 | 944.0 | 89.47 | 44.7 | The future of immune checkpoint therapy. | Padmanee Sharma, James P Allison | Science | 2015 | 25838373 | No |
2672 | 944 | 944.0 | 63.08 | 63.1 | The brain's default mode network. | Marcus E Raichle | Annu Rev Neurosci | 2015 | 25938726 | No |
2673 | 943 | 943.0 | 36.59 | 36.6 | Diversity and ubiquity of K channels. | B Rudy | Neuroscience | 1988 | 2457185 | No |
2674 | 1886 | 943.0 | 92.26 | 46.1 | A simple method to assess exercise behavior in the community. | G Godin, R J Shephard | Can J Appl Sport Sci | 1985 | 4053261 | Yes |
2675 | 943 | 943.0 | 28.05 | 28.1 | Drug delivery and targeting. | R Langer | Nature | 1998 | 9579855 | No |
2676 | 943 | 943.0 | 25.29 | 25.3 | Context and behavioral processes in extinction. | Mark E Bouton | Learn Mem | 2004 | 15466298 | No |
2677 | 1886 | 943.0 | 99.5 | 49.8 | ROS function in redox signaling and oxidative stress. | Michael Schieber, Navdeep S Chandel | Curr Biol | 2014 | 24845678 | No |
2678 | 3770 | 942.5 | 124.39 | 31.1 | Toxic potential of materials at the nanolevel. | Andre Nel, Tian Xia, Lutz Mädler, Ning Li | Science | 2006 | 16456071 | No |
2679 | 3769 | 942.2 | 0.0 | 0.0 | The unlabeled antibody enzyme method of immunohistochemistry: preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes. | L A Sternberger, P H Hardy, J J Cuculis, H G Meyer | J Histochem Cytochem | 1970 | 4192899 | Yes |
2680 | 942 | 942.0 | 0.0 | 0.0 | An improved procedure for serum creatine phosphokinase determination. | S B Rosalki | J Lab Clin Med | 1967 | 4381359 | Yes |
2681 | 1884 | 942.0 | 0.0 | 0.0 | Enzyme-linked immunosorbent assay (ELISA). Quantitative assay of immunoglobulin G. | E Engvall, P Perlmann | Immunochemistry | 1971 | 5135623 | Yes |
2682 | 942 | 942.0 | 21.17 | 21.2 | Osmotic stress signaling and osmoadaptation in yeasts. | Stefan Hohmann | Microbiol Mol Biol Rev | 2002 | 12040128 | No |
2683 | 942 | 942.0 | 0.0 | 0.0 | Starch gel electrophoresis in a discontinous system of buffers. | M D POULIK | Nature | 1957 | 13493570 | Yes |
2684 | 942 | 942.0 | 33.28 | 33.3 | Improving the quality of Web surveys: the Checklist for Reporting Results of Internet E-Surveys (CHERRIES). | Gunther Eysenbach | J Med Internet Res | 2004 | 15471760 | No |
2685 | 942 | 942.0 | 32.6 | 32.6 | MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship. | Amy E Pasquinelli | Nat Rev Genet | 2012 | 22411466 | No |
2686 | 941 | 941.0 | 18.25 | 18.2 | Regulatory T cells in autoimmmunity*. | E M Shevach | Annu Rev Immunol | 2000 | 10837065 | No |
2687 | 941 | 941.0 | 25.05 | 25.1 | Anatomy and regulation of the central melanocortin system. | Roger D Cone | Nat Neurosci | 2005 | 15856065 | No |
2688 | 941 | 941.0 | 0.0 | 0.0 | THE FUNCTION OF THE VERTEBRAL VEINS AND THEIR ROLE IN THE SPREAD OF METASTASES. | O V Batson | Ann Surg | 1940 | 17857618 | Yes |
2689 | 941 | 941.0 | 44.72 | 44.7 | Cytokines in inflammatory bowel disease. | Markus F Neurath | Nat Rev Immunol | 2014 | 24751956 | No |
2690 | 940 | 940.0 | 34.55 | 34.5 | Tumor invasion and metastases--role of the extracellular matrix: Rhoads Memorial Award lecture. | L A Liotta | Cancer Res | 1986 | 2998604 | No |
2691 | 940 | 940.0 | 42.17 | 42.2 | Carnitine--metabolism and functions. | J Bremer | Physiol Rev | 1983 | 6361812 | No |
2692 | 940 | 940.0 | 35.4 | 35.4 | Plasmid complements of Streptococcus lactis NCDO 712 and other lactic streptococci after protoplast-induced curing. | M J Gasson | J Bacteriol | 1983 | 6403500 | Yes |
2693 | 1880 | 940.0 | 75.98 | 38.0 | Modeling and comparison of dissolution profiles. | P Costa, J M Sousa Lobo | Eur J Pharm Sci | 2001 | 11297896 | No |
2694 | 6580 | 940.0 | 235.73 | 33.7 | AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility. | Garrett M Morris, Ruth Huey, William Lindstrom, Michel F Sanner, Richard K Belew, David S Goodsell, Arthur J Olson | J Comput Chem | 2009 | 19399780 | Yes |
2695 | 1880 | 940.0 | 70.0 | 35.0 | Oncology meets immunology: the cancer-immunity cycle. | Daniel S Chen, Ira Mellman | Immunity | 2013 | 23890059 | No |
2696 | 2819 | 939.7 | 111.1 | 37.0 | Qualitative research in health care. Analysing qualitative data. | C Pope, S Ziebland, N Mays | BMJ | 2000 | 10625273 | No |
2697 | 939 | 939.0 | 24.21 | 24.2 | A tension-based theory of morphogenesis and compact wiring in the central nervous system. | D C Van Essen | Nature | 1997 | 9002514 | Yes |
2698 | 1878 | 939.0 | 40.65 | 20.3 | Genomic control for association studies. | B Devlin, K Roeder | Biometrics | 1999 | 11315092 | Yes |
2699 | 939 | 939.0 | 23.36 | 23.4 | Personal genomes: The case of the missing heritability. | Brendan Maher | Nature | 2008 | 18987709 | No |
2700 | 1877 | 938.5 | 44.35 | 22.2 | The significance of digital gene expression profiles. | S Audic, J M Claverie | Genome Res | 1997 | 9331369 | Yes |
2701 | 1876 | 938.0 | 0.0 | 0.0 | Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty. | J M Tanner, R H Whitehouse | Arch Dis Child | 1976 | 952550 | Yes |
2702 | 938 | 938.0 | 0.0 | 0.0 | Mutation selection and the natural history of cancer. | J Cairns | Nature | 1975 | 1143315 | Yes |
2703 | 2814 | 938.0 | 83.58 | 27.9 | Towards a natural system of organisms: proposal for the domains Archaea, Bacteria, and Eucarya. | C R Woese, O Kandler, M L Wheelis | Proc Natl Acad Sci U S A | 1990 | 2112744 | Yes |
2704 | 938 | 938.0 | 51.44 | 51.4 | Substance P. | B Pernow | Pharmacol Rev | 1983 | 6196797 | No |
2705 | 1875 | 937.5 | 38.53 | 19.3 | An automated method for finding molecular complexes in large protein interaction networks. | Gary D Bader, Christopher W V Hogue | BMC Bioinformatics | 2003 | 12525261 | Yes |
2706 | 5623 | 937.2 | 194.37 | 32.4 | A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. | Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier | Science | 2012 | 22745249 | Yes |
2707 | 937 | 937.0 | 46.89 | 46.9 | Bone "mass" and the "mechanostat": a proposal. | H M Frost | Anat Rec | 1987 | 3688455 | Yes |
2708 | 937 | 937.0 | 19.57 | 19.6 | ChIP-seq: advantages and challenges of a maturing technology. | Peter J Park | Nat Rev Genet | 2009 | 19736561 | No |
2709 | 1873 | 936.5 | 72.52 | 36.3 | Modified RECIST (mRECIST) assessment for hepatocellular carcinoma. | Riccardo Lencioni, Josep M Llovet | Semin Liver Dis | 2010 | 20175033 | No |
2710 | 936 | 936.0 | 0.0 | 0.0 | Coupling of enzymes to proteins with glutaraldehyde. Use of the conjugates for the detection of antigens and antibodies. | S Avrameas | Immunochemistry | 1969 | 4975324 | Yes |
2711 | 936 | 936.0 | 16.88 | 16.9 | Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism. | M S Wold | Annu Rev Biochem | 1997 | 9242902 | No |
2712 | 936 | 936.0 | 16.92 | 16.9 | Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation. | Eric C Lai | Nat Genet | 2002 | 11896390 | Yes |
2713 | 936 | 936.0 | 33.39 | 33.4 | The Hospital Anxiety And Depression Scale. | R Philip Snaith | Health Qual Life Outcomes | 2003 | 12914662 | Yes |
2714 | 936 | 936.0 | 0.0 | 0.0 | Simple methods for "staining with lead" at high pH in electron microscopy. | M J KARNOVSKY | J Biophys Biochem Cytol | 1961 | 14454024 | Yes |
2715 | 1871 | 935.5 | 39.97 | 20.0 | Tumour-cell invasion and migration: diversity and escape mechanisms. | Peter Friedl, Katarina Wolf | Nat Rev Cancer | 2003 | 12724734 | No |
2716 | 935 | 935.0 | 34.68 | 34.7 | Antecedent- and response-focused emotion regulation: divergent consequences for experience, expression, and physiology. | J J Gross | J Pers Soc Psychol | 1998 | 9457784 | Yes |
2717 | 935 | 935.0 | 29.17 | 29.2 | Inhibition of return. | Klein | Trends Cogn Sci | 2000 | 10740278 | Yes |
2718 | 1870 | 935.0 | 48.04 | 24.0 | Cellular processing of platinum anticancer drugs. | Dong Wang, Stephen J Lippard | Nat Rev Drug Discov | 2005 | 15789122 | No |
2719 | 935 | 935.0 | 19.93 | 19.9 | mTOR and cancer: insights into a complex relationship. | David M Sabatini | Nat Rev Cancer | 2006 | 16915295 | No |
2720 | 1869 | 934.5 | 55.74 | 27.9 | Chlorophyll fluorescence--a practical guide. | K Maxwell, G N Johnson | J Exp Bot | 2000 | 10938857 | No |
2721 | 1868 | 934.0 | 97.66 | 48.8 | Biology of disease: free radicals and tissue injury. | B A Freeman, J D Crapo | Lab Invest | 1982 | 6290784 | No |
2722 | 934 | 934.0 | 28.53 | 28.5 | Possible role of flanking nucleotides in recognition of the AUG initiator codon by eukaryotic ribosomes. | M Kozak | Nucleic Acids Res | 1981 | 7301588 | Yes |
2723 | 934 | 934.0 | 46.94 | 46.9 | Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment. | S H Safe | Crit Rev Toxicol | 1994 | 8037844 | No |
2724 | 934 | 934.0 | 26.11 | 26.1 | Comparative physiology of salt and water stress. | R. Munns | Plant Cell Environ | 2002 | 11841667 | Yes |
2725 | 934 | 934.0 | 0.0 | 0.0 | Method for the determination of hexosamines in tissues. | N F BOAS | J Biol Chem | 1953 | 13117829 | Yes |
2726 | 934 | 934.0 | 56.69 | 56.7 | Nonalcoholic fatty liver disease: a systematic review. | Mary E Rinella | JAMA | 2015 | 26057287 | No |
2727 | 3734 | 933.5 | 103.46 | 25.9 | Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. | Michael D Greicius, Ben Krasnow, Allan L Reiss, Vinod Menon | Proc Natl Acad Sci U S A | 2003 | 12506194 | Yes |
2728 | 7467 | 933.4 | 226.52 | 28.3 | A method and server for predicting damaging missense mutations. | Ivan A Adzhubei, Steffen Schmidt, Leonid Peshkin, Vasily E Ramensky, Anna Gerasimova, Peer Bork, Alexey S Kondrashov, Shamil R Sunyaev | Nat Methods | 2010 | 20354512 | Yes |
2729 | 933 | 933.0 | 34.9 | 34.9 | The matrix-degrading metalloproteinases. | L M Matrisian | Bioessays | 1992 | 1445287 | No |
2730 | 933 | 933.0 | 0.0 | 0.0 | Protein denaturation. C. Theoretical models for the mechanism of denaturation. | C Tanford | Adv Protein Chem | 1970 | 4912353 | No |
2731 | 933 | 933.0 | 27.71 | 27.7 | Disorders of iron metabolism. | N C Andrews | N Engl J Med | 1999 | 10607817 | No |
2732 | 1866 | 933.0 | 39.32 | 19.7 | Proliferation, cell cycle and apoptosis in cancer. | G I Evan, K H Vousden | Nature | 2001 | 11357141 | No |
2733 | 933 | 933.0 | 32.01 | 32.0 | The pollution of the marine environment by plastic debris: a review. | José G B Derraik | Mar Pollut Bull | 2002 | 12405208 | No |
2734 | 933 | 933.0 | 35.24 | 35.2 | Platelet-rich plasma: evidence to support its use. | Robert E Marx | J Oral Maxillofac Surg | 2004 | 15085519 | No |
2735 | 5597 | 932.8 | 192.82 | 32.1 | Free radicals and antioxidants in normal physiological functions and human disease. | Marian Valko, Dieter Leibfritz, Jan Moncol, Mark T D Cronin, Milan Mazur, Joshua Telser | Int J Biochem Cell Biol | 2007 | 16978905 | No |
2736 | 1865 | 932.5 | 79.54 | 39.8 | Atomic structure and chemistry of human serum albumin. | X M He, D C Carter | Nature | 1992 | 1630489 | Yes |
2737 | 1865 | 932.5 | 55.53 | 27.8 | Molecular mechanisms of action of steroid/thyroid receptor superfamily members. | M J Tsai, B W O'Malley | Annu Rev Biochem | 1994 | 7979245 | No |
2738 | 932 | 932.0 | 0.0 | 0.0 | The interaction of a naphthalene dye with apomyoglobin and apohemoglobin. A fluorescent probe of non-polar binding sites. | L Stryer | J Mol Biol | 1965 | 5867031 | Yes |
2739 | 932 | 932.0 | 22.65 | 22.6 | The columnar organization of the neocortex. | V B Mountcastle | Brain | 1997 | 9153131 | No |
2740 | 932 | 932.0 | 24.51 | 24.5 | The path to ubiquitous and low-cost organic electronic appliances on plastic. | Stephen R Forrest | Nature | 2004 | 15118718 | Yes |
2741 | 932 | 932.0 | 21.86 | 21.9 | Membrane recognition by phospholipid-binding domains. | Mark A Lemmon | Nat Rev Mol Cell Biol | 2008 | 18216767 | No |
2742 | 932 | 932.0 | 26.43 | 26.4 | Recent advances in neuroblastoma. | John M Maris | N Engl J Med | 2010 | 20558371 | No |
2743 | 931 | 931.0 | 31.57 | 31.6 | General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids. | R A Houghten | Proc Natl Acad Sci U S A | 1985 | 2410914 | Yes |
2744 | 931 | 931.0 | 54.41 | 54.4 | A cognitive approach to panic. | D M Clark | Behav Res Ther | 1986 | 3741311 | Yes |
2745 | 931 | 931.0 | 26.16 | 26.2 | P-450 metabolites of arachidonic acid in the control of cardiovascular function. | Richard J Roman | Physiol Rev | 2002 | 11773611 | No |
2746 | 1862 | 931.0 | 66.5 | 33.2 | Health effects of fine particulate air pollution: lines that connect. | C Arden Pope, Douglas W Dockery | J Air Waste Manag Assoc | 2006 | 16805397 | No |
2747 | 930 | 930.0 | 38.06 | 38.1 | AmpC beta-lactamases. | George A Jacoby | Clin Microbiol Rev | 2009 | 19136439 | No |
2748 | 930 | 930.0 | 24.93 | 24.9 | Tumour necrosis factor and cancer. | Frances Balkwill | Nat Rev Cancer | 2009 | 19343034 | No |
2749 | 1859 | 929.5 | 54.18 | 27.1 | Morris water maze: procedures for assessing spatial and related forms of learning and memory. | Charles V Vorhees, Michael T Williams | Nat Protoc | 2006 | 17406317 | Yes |
2750 | 1859 | 929.5 | 48.77 | 24.4 | Modes of resistance to anti-angiogenic therapy. | Gabriele Bergers, Douglas Hanahan | Nat Rev Cancer | 2008 | 18650835 | No |
2751 | 2787 | 929.0 | 104.79 | 34.9 | Oxidants, antioxidants, and the degenerative diseases of aging. | B N Ames, M K Shigenaga, T M Hagen | Proc Natl Acad Sci U S A | 1993 | 8367443 | No |
2752 | 929 | 929.0 | 21.15 | 21.1 | An overview of epithelio-mesenchymal transformation. | E D Hay | Acta Anat (Basel) | 1995 | 8714286 | No |
2753 | 929 | 929.0 | 21.35 | 21.4 | Up on the tightrope: natural killer cell activation and inhibition. | Lewis L Lanier | Nat Immunol | 2008 | 18425106 | No |
2754 | 1856 | 928.0 | 42.88 | 21.4 | Checkpoints: controls that ensure the order of cell cycle events. | L H Hartwell, T A Weinert | Science | 1989 | 2683079 | No |
2755 | 4640 | 928.0 | 189.05 | 37.8 | Posttraumatic stress disorder in the National Comorbidity Survey. | R C Kessler, A Sonnega, E Bromet, M Hughes, C B Nelson | Arch Gen Psychiatry | 1995 | 7492257 | Yes |
2756 | 928 | 928.0 | 30.03 | 30.0 | Leishmaniasis. | B L Herwaldt | Lancet | 1999 | 10513726 | No |
2757 | 928 | 928.0 | 23.02 | 23.0 | Complement. Second of two parts. | M J Walport | N Engl J Med | 2001 | 11297706 | No |
2758 | 1855 | 927.5 | 66.8 | 33.4 | Inflammatory mechanisms in obesity. | Margaret F Gregor, Gökhan S Hotamisligil | Annu Rev Immunol | 2011 | 21219177 | No |
2759 | 3710 | 927.5 | 130.41 | 32.6 | clusterProfiler: an R package for comparing biological themes among gene clusters. | Guangchuang Yu, Li-Gen Wang, Yanyan Han, Qing-Yu He | OMICS | 2012 | 22455463 | Yes |
2760 | 927 | 927.0 | 29.7 | 29.7 | The effects of stressful life events on depression. | R C Kessler | Annu Rev Psychol | 1997 | 9046559 | No |
2761 | 1854 | 927.0 | 59.02 | 29.5 | ASCORBATE AND GLUTATHIONE: Keeping Active Oxygen Under Control. | Graham Noctor, Christine H. Foyer | Annu Rev Plant Physiol Plant Mol Biol | 1998 | 15012235 | Yes |
2762 | 927 | 927.0 | 31.81 | 31.8 | Water as an active constituent in cell biology. | Philip Ball | Chem Rev | 2008 | 18095715 | No |
2763 | 1854 | 927.0 | 48.18 | 24.1 | Cell cycle, CDKs and cancer: a changing paradigm. | Marcos Malumbres, Mariano Barbacid | Nat Rev Cancer | 2009 | 19238148 | No |
2764 | 926 | 926.0 | 19.2 | 19.2 | The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities. | Y Yarden | Eur J Cancer | 2001 | 11597398 | No |
2765 | 926 | 926.0 | 24.62 | 24.6 | Differential projections of the infralimbic and prelimbic cortex in the rat. | Robert P Vertes | Synapse | 2004 | 14579424 | Yes |
2766 | 1852 | 926.0 | 60.0 | 30.0 | Tumor metastasis: molecular insights and evolving paradigms. | Scott Valastyan, Robert A Weinberg | Cell | 2011 | 22000009 | No |
2767 | 1851 | 925.5 | 45.01 | 22.5 | Regeneration beyond the glial scar. | Jerry Silver, Jared H Miller | Nat Rev Neurosci | 2004 | 14735117 | No |
2768 | 10180 | 925.5 | 309.18 | 28.1 | The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. | Aaron McKenna, Matthew Hanna, Eric Banks, Andrey Sivachenko, Kristian Cibulskis, Andrew Kernytsky, Kiran Garimella, David Altshuler, Stacey Gabriel, Mark Daly, Mark A DePristo | Genome Res | 2010 | 20644199 | Yes |
2769 | 1850 | 925.0 | 0.0 | 0.0 | Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome. | C B Lozzio, B B Lozzio | Blood | 1975 | 163658 | Yes |
2770 | 925 | 925.0 | 0.0 | 0.0 | Why people use health services. | I M Rosenstock | Milbank Mem Fund Q | 1966 | 5967464 | Yes |
2771 | 1850 | 925.0 | 43.18 | 21.6 | The Hsp70 and Hsp60 chaperone machines. | B Bukau, A L Horwich | Cell | 1998 | 9476895 | No |
2772 | 5550 | 925.0 | 137.45 | 22.9 | Principal components analysis corrects for stratification in genome-wide association studies. | Alkes L Price, Nick J Patterson, Robert M Plenge, Michael E Weinblatt, Nancy A Shadick, David Reich | Nat Genet | 2006 | 16862161 | Yes |
2773 | 925 | 925.0 | 47.57 | 47.6 | Exploring Structure-Activity Data Using the Landscape Paradigm. | Rajarshi Guha | Wiley Interdiscip Rev Comput Mol Sci | 2012 | 24163705 | Yes |
2774 | 1849 | 924.5 | 76.03 | 38.0 | Unidentified curved bacilli on gastric epithelium in active chronic gastritis. | J R Warren, B Marshall | Lancet | 1983 | 6134060 | Yes |
2775 | 924 | 924.0 | 29.57 | 29.6 | Pathogenesis of dengue: challenges to molecular biology. | S B Halstead | Science | 1988 | 3277268 | No |
2776 | 924 | 924.0 | 25.06 | 25.1 | Program DYNAFIT for the analysis of enzyme kinetic data: application to HIV proteinase. | P Kuzmic | Anal Biochem | 1996 | 8660575 | Yes |
2777 | 3696 | 924.0 | 105.83 | 26.5 | C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. | P M Ridker, C H Hennekens, J E Buring, N Rifai | N Engl J Med | 2000 | 10733371 | Yes |
2778 | 924 | 924.0 | 23.74 | 23.7 | Effect of carvedilol on outcome after myocardial infarction in patients with left-ventricular dysfunction: the CAPRICORN randomised trial. | H J Dargie | Lancet | 2001 | 11356434 | Yes |
2779 | 924 | 924.0 | 26.06 | 26.1 | Looking into the functional architecture of the brain with diffusion MRI. | Denis Le Bihan | Nat Rev Neurosci | 2003 | 12778119 | No |
2780 | 924 | 924.0 | 46.52 | 46.5 | α-band oscillations, attention, and controlled access to stored information. | Wolfgang Klimesch | Trends Cogn Sci | 2012 | 23141428 | No |
2781 | 2771 | 923.7 | 83.39 | 27.8 | A nonparametric method for automatic correction of intensity nonuniformity in MRI data. | J G Sled, A P Zijdenbos, A C Evans | IEEE Trans Med Imaging | 1998 | 9617910 | Yes |
2782 | 1847 | 923.5 | 64.49 | 32.2 | Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. | P Brugada, J Brugada | J Am Coll Cardiol | 1992 | 1309182 | Yes |
2783 | 3694 | 923.5 | 133.99 | 33.5 | Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma. | N Weidner, J P Semple, W R Welch, J Folkman | N Engl J Med | 1991 | 1701519 | Yes |
2784 | 1847 | 923.5 | 55.05 | 27.5 | Oxidative stress, caloric restriction, and aging. | R S Sohal, R Weindruch | Science | 1996 | 8658196 | No |
2785 | 923 | 923.0 | 27.29 | 27.3 | Two-stage model of memory trace formation: a role for "noisy" brain states. | G Buzsáki | Neuroscience | 1989 | 2687720 | No |
2786 | 923 | 923.0 | 61.16 | 61.2 | The tension-stress effect on the genesis and growth of tissues: Part II. The influence of the rate and frequency of distraction. | G A Ilizarov | Clin Orthop Relat Res | 1989 | 2912628 | Yes |
2787 | 923 | 923.0 | 62.91 | 62.9 | Psychosocial resilience and protective mechanisms. | Michael Rutter | Am J Orthopsychiatry | 1987 | 3303954 | No |
2788 | 923 | 923.0 | 34.97 | 35.0 | Effect of anoxia on ion distribution in the brain. | A J Hansen | Physiol Rev | 1985 | 3880896 | No |
2789 | 923 | 923.0 | 27.55 | 27.6 | Molecular genetics of colorectal cancer. | Eric R Fearon | Annu Rev Pathol | 2011 | 21090969 | No |
2790 | 2768 | 922.7 | 184.82 | 61.6 | Some statistical methods useful in circulation research. | S Wallenstein, C L Zucker, J L Fleiss | Circ Res | 1980 | 7379260 | Yes |
2791 | 1845 | 922.5 | 0.0 | 0.0 | A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. | R L Juliano, V Ling | Biochim Biophys Acta | 1976 | 990323 | Yes |
2792 | 1845 | 922.5 | 51.76 | 25.9 | Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. | Subhra K Biswas, Alberto Mantovani | Nat Immunol | 2010 | 20856220 | No |
2793 | 922 | 922.0 | 0.0 | 0.0 | Cell lines derived from late embryonic stages of Drosophila melanogaster. | I Schneider | J Embryol Exp Morphol | 1972 | 4625067 | Yes |
2794 | 922 | 922.0 | 30.0 | 30.0 | Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution. | J Deisenhofer | Biochemistry | 1981 | 7236608 | Yes |
2795 | 922 | 922.0 | 39.37 | 39.4 | Density matrix formulation for quantum renormalization groups. | White | Phys Rev Lett | 1992 | 10046608 | Yes |
2796 | 1844 | 922.0 | 49.85 | 24.9 | A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. | J N Cohn, G Tognoni | N Engl J Med | 2001 | 11759645 | Yes |
2797 | 922 | 922.0 | 20.14 | 20.1 | Automated NMR structure calculation with CYANA. | Peter Güntert | Methods Mol Biol | 2004 | 15318003 | Yes |
2798 | 2766 | 922.0 | 98.55 | 32.9 | SeaView version 4: A multiplatform graphical user interface for sequence alignment and phylogenetic tree building. | Manolo Gouy, Stéphane Guindon, Olivier Gascuel | Mol Biol Evol | 2010 | 19854763 | Yes |
2799 | 3687 | 921.8 | 104.25 | 26.1 | An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. | Joseph A Maldjian, Paul J Laurienti, Robert A Kraft, Jonathan H Burdette | Neuroimage | 2003 | 12880848 | Yes |
2800 | 1843 | 921.5 | 78.44 | 39.2 | Physiological parameters in laboratory animals and humans. | B Davies, T Morris | Pharm Res | 1993 | 8378254 | No |
2801 | 921 | 921.0 | 0.0 | 0.0 | Ruthenium red and violet. I. Chemistry, purification, methods of use for electron microscopy and mechanism of action. | J H Luft | Anat Rec | 1971 | 4108333 | Yes |
2802 | 921 | 921.0 | 22.5 | 22.5 | MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. | R N Germain | Cell | 1994 | 8293464 | No |
2803 | 920 | 920.0 | 52.13 | 52.1 | Environmentally induced oxidative stress in aquatic animals. | Volodymyr I Lushchak | Aquat Toxicol | 2011 | 21074869 | No |
2804 | 1839 | 919.5 | 159.9 | 80.0 | Facial nerve grading system. | J W House, D E Brackmann | Otolaryngol Head Neck Surg | 1985 | 3921901 | Yes |
2805 | 1839 | 919.5 | 0.0 | 0.0 | A rapid, sensitive, and specific method for the determination of protein in dilute solution. | W Schaffner, C Weissmann | Anal Biochem | 1973 | 4128882 | Yes |
2806 | 919 | 919.0 | 41.98 | 42.0 | The P300 wave of the human event-related potential. | T W Picton | J Clin Neurophysiol | 1992 | 1464675 | No |
2807 | 919 | 919.0 | 0.0 | 0.0 | Studies on phosphatidylcholine vesicles. Formation and physical characteristics. | C Huang | Biochemistry | 1969 | 5777332 | Yes |
2808 | 919 | 919.0 | 32.68 | 32.7 | Context, time, and memory retrieval in the interference paradigms of Pavlovian learning. | M E Bouton | Psychol Bull | 1993 | 8346330 | No |
2809 | 919 | 919.0 | 22.13 | 22.1 | GLIA: listening and talking to the synapse. | P G Haydon | Nat Rev Neurosci | 2001 | 11256079 | No |
2810 | 1838 | 919.0 | 62.6 | 31.3 | Titanium dioxide nanomaterials: synthesis, properties, modifications, and applications. | Xiaobo Chen, Samuel S Mao | Chem Rev | 2007 | 17590053 | Yes |
2811 | 1838 | 919.0 | 75.07 | 37.5 | How good are my data and what is the resolution? | Philip R Evans, Garib N Murshudov | Acta Crystallogr D Biol Crystallogr | 2013 | 23793146 | Yes |
2812 | 2755 | 918.3 | 84.62 | 28.2 | Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. | Robert D Schreiber, Lloyd J Old, Mark J Smyth | Science | 2011 | 21436444 | No |
2813 | 918 | 918.0 | 0.0 | 0.0 | Structure and function of intercellular junctions. | L A Staehelin | Int Rev Cytol | 1974 | 4611943 | No |
2814 | 1836 | 918.0 | 42.13 | 21.1 | Dynamic instability of microtubule growth. | T Mitchison, M Kirschner | Nature | 1984 | 6504138 | Yes |
2815 | 918 | 918.0 | 21.45 | 21.4 | Oxidant signals and oxidative stress. | Toren Finkel | Curr Opin Cell Biol | 2003 | 12648682 | No |
2816 | 918 | 918.0 | 29.93 | 29.9 | Disseminating innovations in health care. | Donald M Berwick | JAMA | 2003 | 12697800 | Yes |
2817 | 918 | 918.0 | 36.11 | 36.1 | Polybrominated diphenyl ethers in the environment and in people: a meta-analysis of concentrations. | Ronald A Hites | Environ Sci Technol | 2004 | 14998004 | Yes |
2818 | 918 | 918.0 | 32.39 | 32.4 | phangorn: phylogenetic analysis in R. | Klaus Peter Schliep | Bioinformatics | 2011 | 21169378 | Yes |
2819 | 917 | 917.0 | 28.49 | 28.5 | The mitochondrial electron transport and oxidative phosphorylation system. | Y Hatefi | Annu Rev Biochem | 1985 | 2862839 | No |
2820 | 917 | 917.0 | 0.0 | 0.0 | The prevalence of 'alexithymic' characteristics in psychosomatic patients. | P E Sifneos | Psychother Psychosom | 1973 | 4770536 | Yes |
2821 | 917 | 917.0 | 18.36 | 18.4 | The ubiquitin-proteasome pathway: on protein death and cell life. | A Ciechanover | EMBO J | 1998 | 9857172 | No |
2822 | 5501 | 916.8 | 199.11 | 33.2 | Prevalence of overweight and obesity in the United States, 1999-2004. | Cynthia L Ogden, Margaret D Carroll, Lester R Curtin, Margaret A McDowell, Carolyn J Tabak, Katherine M Flegal | JAMA | 2006 | 16595758 | Yes |
2823 | 1833 | 916.5 | 58.43 | 29.2 | Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications. | M A Pfeffer, E Braunwald | Circulation | 1990 | 2138525 | No |
2824 | 916 | 916.0 | 0.0 | 0.0 | Origin of concatemeric T7 DNA. | J D Watson | Nat New Biol | 1972 | 4507727 | Yes |
2825 | 916 | 916.0 | 25.27 | 25.3 | Life, death, and the pursuit of apoptosis. | E White | Genes Dev | 1996 | 8557188 | No |
2826 | 916 | 916.0 | 19.8 | 19.8 | VEGF and the quest for tumour angiogenesis factors. | Napoleone Ferrara | Nat Rev Cancer | 2002 | 12360282 | No |
2827 | 1832 | 916.0 | 55.54 | 27.8 | Hydrogels for tissue engineering: scaffold design variables and applications. | Jeanie L Drury, David J Mooney | Biomaterials | 2003 | 12922147 | No |
2828 | 916 | 916.0 | 44.85 | 44.9 | What is self-rated health and why does it predict mortality? Towards a unified conceptual model. | Marja Jylhä | Soc Sci Med | 2009 | 19520474 | Yes |
2829 | 1831 | 915.5 | 33.14 | 16.6 | A synthetic oscillatory network of transcriptional regulators. | M B Elowitz, S Leibler | Nature | 2000 | 10659856 | Yes |
2830 | 915 | 915.0 | 41.07 | 41.1 | A cognitive model of drug urges and drug-use behavior: role of automatic and nonautomatic processes. | S T Tiffany | Psychol Rev | 1990 | 2186423 | No |
2831 | 915 | 915.0 | 29.45 | 29.4 | Limbic-cortical dysregulation: a proposed model of depression. | H S Mayberg | J Neuropsychiatry Clin Neurosci | 1997 | 9276848 | No |
2832 | 1830 | 915.0 | 39.52 | 19.8 | Community structure in social and biological networks. | M Girvan, M E J Newman | Proc Natl Acad Sci U S A | 2002 | 12060727 | No |
2833 | 915 | 915.0 | 28.37 | 28.4 | Epidemiology of women and depression. | Ronald C Kessler | J Affect Disord | 2003 | 12646294 | Yes |
2834 | 5486 | 914.3 | 234.46 | 39.1 | The occurrence of sleep-disordered breathing among middle-aged adults. | T Young, M Palta, J Dempsey, J Skatrud, S Weber, S Badr | N Engl J Med | 1993 | 8464434 | Yes |
2835 | 4571 | 914.2 | 98.19 | 19.6 | Electrostatics of nanosystems: application to microtubules and the ribosome. | N A Baker, D Sept, S Joseph, M J Holst, J A McCammon | Proc Natl Acad Sci U S A | 2001 | 11517324 | Yes |
2836 | 914 | 914.0 | 33.84 | 33.8 | The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions. | R G Gerrity | Am J Pathol | 1981 | 7234961 | Yes |
2837 | 914 | 914.0 | 32.1 | 32.1 | Reducing children's television viewing to prevent obesity: a randomized controlled trial. | T N Robinson | JAMA | 1999 | 10546696 | Yes |
2838 | 1828 | 914.0 | 0.0 | 0.0 | Studies of marine planktonic diatoms. I. Cyclotella nana Hustedt, and Detonula confervacea (cleve) Gran. | R R GUILLARD, J H RYTHER | Can J Microbiol | 1962 | 13902807 | Yes |
2839 | 1828 | 914.0 | 44.12 | 22.1 | Regulation of translation initiation in eukaryotes: mechanisms and biological targets. | Nahum Sonenberg, Alan G Hinnebusch | Cell | 2009 | 19239892 | No |
2840 | 1828 | 914.0 | 68.11 | 34.1 | Stochastic relaxation, gibbs distributions, and the bayesian restoration of images. | S Geman, D Geman | IEEE Trans Pattern Anal Mach Intell | 1984 | 22499653 | Yes |
2841 | 1827 | 913.5 | 76.73 | 38.4 | Functional interactions between the gut microbiota and host metabolism. | Valentina Tremaroli, Fredrik Bäckhed | Nature | 2012 | 22972297 | No |
2842 | 1826 | 913.0 | 69.52 | 34.8 | Population growth makes waves in the distribution of pairwise genetic differences. | A R Rogers, H Harpending | Mol Biol Evol | 1992 | 1316531 | Yes |
2843 | 1824 | 912.0 | 49.17 | 24.6 | Hepatitis C virus infection. | G M Lauer, B D Walker | N Engl J Med | 2001 | 11439948 | No |
2844 | 912 | 912.0 | 29.67 | 29.7 | Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes--a meta-analysis. | P Vestergaard | Osteoporos Int | 2007 | 17068657 | No |
2845 | 1823 | 911.5 | 82.9 | 41.5 | Van der Waals heterostructures. | A K Geim, I V Grigorieva | Nature | 2013 | 23887427 | Yes |
2846 | 1822 | 911.0 | 43.98 | 22.0 | Mitogen-activated protein kinase pathways. | M J Robinson, M H Cobb | Curr Opin Cell Biol | 1997 | 9069255 | No |
2847 | 1822 | 911.0 | 37.68 | 18.8 | Wnt signaling: a common theme in animal development. | K M Cadigan, R Nusse | Genes Dev | 1997 | 9407023 | No |
2848 | 1822 | 911.0 | 44.8 | 22.4 | Long-term potentiation--a decade of progress? | R C Malenka, R A Nicoll | Science | 1999 | 10489359 | No |
2849 | 911 | 911.0 | 26.01 | 26.0 | Automatic quantitation of localized in vivo 1H spectra with LCModel. | S W Provencher | NMR Biomed | 2001 | 11410943 | Yes |
2850 | 911 | 911.0 | 22.21 | 22.2 | Molecular imaging of cancer with positron emission tomography. | Sanjiv Sam Gambhir | Nat Rev Cancer | 2002 | 12209157 | No |
2851 | 911 | 911.0 | 0.0 | 0.0 | Relative and absolute strength of response as a function of frequency of reinforcement. | R J HERRNSTEIN | J Exp Anal Behav | 1961 | 13713775 | Yes |
2852 | 911 | 911.0 | 98.69 | 98.7 | Minimap2: pairwise alignment for nucleotide sequences. | Heng Li | Bioinformatics | 2018 | 29750242 | Yes |
2853 | 910 | 910.0 | 46.03 | 46.0 | Freezing of living cells: mechanisms and implications. | P Mazur | Am J Physiol | 1984 | 6383068 | No |
2854 | 2730 | 910.0 | 90.05 | 30.0 | Spirometric reference values from a sample of the general U.S. population. | J L Hankinson, J R Odencrantz, K B Fedan | Am J Respir Crit Care Med | 1999 | 9872837 | Yes |
2855 | 910 | 910.0 | 23.43 | 23.4 | The prefrontal cortex--an update: time is of the essence. | J M Fuster | Neuron | 2001 | 11394996 | No |
2856 | 910 | 910.0 | 0.0 | 0.0 | The anterior approach for removal of ruptured cervical disks. | R B CLOWARD | J Neurosurg | 1958 | 13599052 | Yes |
2857 | 1819 | 909.5 | 29.48 | 14.7 | Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis. | T Lee, L Luo | Neuron | 1999 | 10197526 | Yes |
2858 | 909 | 909.0 | 41.96 | 42.0 | Transduction of psychosocial stress into the neurobiology of recurrent affective disorder. | R M Post | Am J Psychiatry | 1992 | 1353322 | No |
2859 | 909 | 909.0 | 22.63 | 22.6 | Target-oriented and diversity-oriented organic synthesis in drug discovery. | S L Schreiber | Science | 2000 | 10720315 | No |
2860 | 909 | 909.0 | 21.79 | 21.8 | Measuring information transfer | Schreiber | Phys Rev Lett | 2000 | 10991308 | Yes |
2861 | 909 | 909.0 | 30.82 | 30.8 | Insecticide-treated bed nets and curtains for preventing malaria. | C Lengeler | Cochrane Database Syst Rev | 2004 | 15106149 | No |
2862 | 909 | 909.0 | 25.51 | 25.5 | Spontaneous low-frequency BOLD signal fluctuations: an fMRI investigation of the resting-state default mode of brain function hypothesis. | Peter Fransson | Hum Brain Mapp | 2005 | 15852468 | Yes |
2863 | 1817 | 908.5 | 49.62 | 24.8 | Prediction of protein secondary structure at better than 70% accuracy. | B Rost, C Sander | J Mol Biol | 1993 | 8345525 | Yes |
2864 | 1817 | 908.5 | 0.0 | 0.0 | Primary carcinoma of the liver: a study of 100 cases among 48,900 necropsies. | H A EDMONDSON, P E STEINER | Cancer | 1954 | 13160935 | Yes |
2865 | 908 | 908.0 | 20.31 | 20.3 | Fibrotic disease and the T(H)1/T(H)2 paradigm. | Thomas A Wynn | Nat Rev Immunol | 2004 | 15286725 | No |
2866 | 908 | 908.0 | 30.04 | 30.0 | Cholinesterase inhibitors for Alzheimer's disease. | J Birks | Cochrane Database Syst Rev | 2006 | 16437532 | No |
2867 | 2722 | 907.3 | 89.84 | 29.9 | A sensitive and reliable locomotor rating scale for open field testing in rats. | D M Basso, M S Beattie, J C Bresnahan | J Neurotrauma | 1995 | 7783230 | Yes |
2868 | 907 | 907.0 | 0.0 | 0.0 | Strategy and tactics in protein chemistry. | B S Hartley | Biochem J | 1970 | 4923920 | No |
2869 | 907 | 907.0 | 22.48 | 22.5 | BIONJ: an improved version of the NJ algorithm based on a simple model of sequence data. | O Gascuel | Mol Biol Evol | 1997 | 9254330 | Yes |
2870 | 1814 | 907.0 | 43.1 | 21.6 | Roles of CHOP/GADD153 in endoplasmic reticulum stress. | S Oyadomari, M Mori | Cell Death Differ | 2004 | 14685163 | No |
2871 | 907 | 907.0 | 17.7 | 17.7 | NFAT proteins: key regulators of T-cell development and function. | Fernando Macian | Nat Rev Immunol | 2005 | 15928679 | No |
2872 | 2720 | 906.7 | 65.41 | 21.8 | Generation of germline-competent induced pluripotent stem cells. | Keisuke Okita, Tomoko Ichisaka, Shinya Yamanaka | Nature | 2007 | 17554338 | Yes |
2873 | 1812 | 906.0 | 63.45 | 31.7 | Excitatory amino acids as a final common pathway for neurologic disorders. | S A Lipton, P A Rosenberg | N Engl J Med | 1994 | 7905600 | No |
2874 | 906 | 906.0 | 33.78 | 33.8 | Understanding diagnostic tests 3: Receiver operating characteristic curves. | Anthony K Akobeng | Acta Paediatr | 2007 | 17376185 | No |
2875 | 906 | 906.0 | 36.57 | 36.6 | Tumor delivery of macromolecular drugs based on the EPR effect. | Vladimir Torchilin | Adv Drug Deliv Rev | 2011 | 20304019 | No |
2876 | 1811 | 905.5 | 58.72 | 29.4 | Ageing and Parkinson's disease: substantia nigra regional selectivity. | J M Fearnley, A J Lees | Brain | 1991 | 1933245 | Yes |
2877 | 1810 | 905.0 | 40.91 | 20.5 | Homeobox genes and axial patterning. | W McGinnis, R Krumlauf | Cell | 1992 | 1346368 | No |
2878 | 905 | 905.0 | 0.0 | 0.0 | Stimulus-secretion coupling: the concept and clues from chromaffin and other cells. | W W Douglas | Br J Pharmacol | 1968 | 4882190 | No |
2879 | 905 | 905.0 | 56.56 | 56.6 | The clinical application of the biopsychosocial model. | G L Engel | Am J Psychiatry | 1980 | 7369396 | Yes |
2880 | 905 | 905.0 | 23.02 | 23.0 | ALSCRIPT: a tool to format multiple sequence alignments. | G J Barton | Protein Eng | 1993 | 8433969 | Yes |
2881 | 5430 | 905.0 | 228.44 | 38.1 | Antioxidant activity applying an improved ABTS radical cation decolorization assay. | R Re, N Pellegrini, A Proteggente, A Pannala, M Yang, C Rice-Evans | Free Radic Biol Med | 1999 | 10381194 | Yes |
2882 | 905 | 905.0 | 35.12 | 35.1 | Amino acids: metabolism, functions, and nutrition. | Guoyao Wu | Amino Acids | 2009 | 19301095 | No |
2883 | 904 | 904.0 | 38.86 | 38.9 | The phenomenon of the acute phase response. | I Kushner | Ann N Y Acad Sci | 1982 | 7046585 | No |
2884 | 904 | 904.0 | 26.74 | 26.7 | The Trk family of neurotrophin receptors. | M Barbacid | J Neurobiol | 1994 | 7852993 | No |
2885 | 904 | 904.0 | 17.95 | 17.9 | Chronic myeloid leukemia. | C L Sawyers | N Engl J Med | 1999 | 10219069 | No |
2886 | 904 | 904.0 | 23.95 | 23.9 | Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. | J Denis McGarry | Diabetes | 2002 | 11756317 | No |
2887 | 904 | 904.0 | 22.75 | 22.8 | New ideas about atrial fibrillation 50 years on. | Stanley Nattel | Nature | 2002 | 11805846 | No |
2888 | 904 | 904.0 | 19.18 | 19.2 | Telomeres and human disease: ageing, cancer and beyond. | Maria A Blasco | Nat Rev Genet | 2005 | 16136653 | No |
2889 | 4519 | 903.8 | 193.49 | 38.7 | The hallmarks of aging. | Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer | Cell | 2013 | 23746838 | No |
2890 | 3613 | 903.2 | 103.65 | 25.9 | MEGA2: molecular evolutionary genetics analysis software. | S Kumar, K Tamura, I B Jakobsen, M Nei | Bioinformatics | 2001 | 11751241 | Yes |
2891 | 903 | 903.0 | 0.0 | 0.0 | Preparation of rat liver cells. 3. Enzymatic requirements for tissue dispersion. | P O Seglen | Exp Cell Res | 1973 | 4358115 | Yes |
2892 | 903 | 903.0 | 62.79 | 62.8 | Rating scales to assess depression in school-aged children. | M Kovacs | Acta Paedopsychiatr | 1981 | 7025571 | Yes |
2893 | 1806 | 903.0 | 53.53 | 26.8 | Protein oxidation in aging, disease, and oxidative stress. | B S Berlett, E R Stadtman | J Biol Chem | 1997 | 9252331 | No |
2894 | 1806 | 903.0 | 47.52 | 23.8 | Inflammation, stress, and diabetes. | Kathryn E Wellen, Gökhan S Hotamisligil | J Clin Invest | 2005 | 15864338 | No |
2895 | 1805 | 902.5 | 65.33 | 32.7 | Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction. | J L Weber, P E May | Am J Hum Genet | 1989 | 2916582 | Yes |
2896 | 902 | 902.0 | 25.35 | 25.4 | Chemistry and biology of the immunophilins and their immunosuppressive ligands. | S L Schreiber | Science | 1991 | 1702904 | No |
2897 | 902 | 902.0 | 0.0 | 0.0 | 6-Hydroxy-dopamine induced degeneration of central monoamine neurons. | U Ungerstedt | Eur J Pharmacol | 1968 | 5718510 | Yes |
2898 | 902 | 902.0 | 17.16 | 17.2 | TNF/TNFR family members in costimulation of T cell responses. | Tania H Watts | Annu Rev Immunol | 2005 | 15771565 | No |
2899 | 4508 | 901.6 | 183.22 | 36.6 | Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. | J S Beckman, T W Beckman, J Chen, P A Marshall, B A Freeman | Proc Natl Acad Sci U S A | 1990 | 2154753 | Yes |
2900 | 901 | 901.0 | 19.11 | 19.1 | Initiation of translation in prokaryotes and eukaryotes. | M Kozak | Gene | 1999 | 10395892 | No |
2901 | 5404 | 900.7 | 152.14 | 25.4 | An obesity-associated gut microbiome with increased capacity for energy harvest. | Peter J Turnbaugh, Ruth E Ley, Michael A Mahowald, Vincent Magrini, Elaine R Mardis, Jeffrey I Gordon | Nature | 2006 | 17183312 | Yes |
2902 | 1801 | 900.5 | 43.41 | 21.7 | microRNA functions. | Natascha Bushati, Stephen M Cohen | Annu Rev Cell Dev Biol | 2007 | 17506695 | No |
2903 | 900 | 900.0 | 25.44 | 25.4 | Tumor suppressor genes. | R A Weinberg | Science | 1991 | 1659741 | No |
2904 | 900 | 900.0 | 115.34 | 115.3 | The analysis of errors in orthodontic measurements. | W J Houston | Am J Orthod | 1983 | 6573846 | Yes |
2905 | 1800 | 900.0 | 93.91 | 47.0 | Rapid procedure for detection and isolation of large and small plasmids. | C I Kado, S T Liu | J Bacteriol | 1981 | 7009583 | Yes |
2906 | 1800 | 900.0 | 37.48 | 18.7 | CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. | A M Thornton, E M Shevach | J Exp Med | 1998 | 9670041 | Yes |
2907 | 900 | 900.0 | 27.61 | 27.6 | The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. | R A Jain | Biomaterials | 2000 | 11055295 | No |
2908 | 900 | 900.0 | 19.24 | 19.2 | Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. | A S Baldwin | J Clin Invest | 2001 | 11160144 | No |
2909 | 900 | 900.0 | 23.96 | 24.0 | Current concepts of the pathogenesis of the acute coronary syndromes. | P Libby | Circulation | 2001 | 11457759 | No |
2910 | 900 | 900.0 | 0.0 | 0.0 | The relation of the trail making test to organic brain damage. | R M REITAN | J Consult Psychol | 1955 | 13263471 | Yes |
2911 | 2700 | 900.0 | 76.87 | 25.6 | Functional porous coordination polymers. | Susumu Kitagawa, Ryo Kitaura, Shin-ichiro Noro | Angew Chem Int Ed Engl | 2004 | 15114565 | Yes |
2912 | 900 | 900.0 | 31.51 | 31.5 | G(ST) and its relatives do not measure differentiation. | Lou Jost | Mol Ecol | 2008 | 19238703 | Yes |
2913 | 4498 | 899.6 | 90.31 | 18.1 | The protein kinase complement of the human genome. | G Manning, D B Whyte, R Martinez, T Hunter, S Sudarsanam | Science | 2002 | 12471243 | No |
2914 | 1799 | 899.5 | 45.28 | 22.6 | Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set. | N Sreerama, R W Woody | Anal Biochem | 2000 | 11112271 | Yes |
2915 | 3597 | 899.2 | 100.21 | 25.1 | The epidemiology of sepsis in the United States from 1979 through 2000. | Greg S Martin, David M Mannino, Stephanie Eaton, Marc Moss | N Engl J Med | 2003 | 12700374 | Yes |
2916 | 899 | 899.0 | 0.0 | 0.0 | Antigen-antibody reactions in gels. | O OUCHTERLONY | Acta Pathol Microbiol Scand | 1949 | 18143039 | Yes |
2917 | 5392 | 898.7 | 162.99 | 27.2 | Prediction of coronary heart disease using risk factor categories. | P W Wilson, R B D'Agostino, D Levy, A M Belanger, H Silbershatz, W B Kannel | Circulation | 1998 | 9603539 | Yes |
2918 | 898 | 898.0 | 67.84 | 67.8 | Calcium phosphate ceramics as hard tissue prosthetics. | M Jarcho | Clin Orthop Relat Res | 1981 | 7018783 | No |
2919 | 1796 | 898.0 | 38.59 | 19.3 | Cellular functions regulated by Src family kinases. | S M Thomas, J S Brugge | Annu Rev Cell Dev Biol | 1997 | 9442882 | No |
2920 | 898 | 898.0 | 30.11 | 30.1 | Riddle of biofilm resistance. | K Lewis | Antimicrob Agents Chemother | 2001 | 11257008 | No |
2921 | 898 | 898.0 | 22.7 | 22.7 | A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage. | Lawrence Steinman | Nat Med | 2007 | 17290272 | No |
2922 | 897 | 897.0 | 23.73 | 23.7 | Seed Germination and Dormancy. | J. D. Bewley | Plant Cell | 1997 | 12237375 | Yes |
2923 | 896 | 896.0 | 40.35 | 40.4 | Spatial localization in NMR spectroscopy in vivo. | P A Bottomley | Ann N Y Acad Sci | 1987 | 3326459 | No |
2924 | 896 | 896.0 | 23.87 | 23.9 | Aptamers: an emerging class of molecules that rival antibodies in diagnostics. | S D Jayasena | Clin Chem | 1999 | 10471678 | No |
2925 | 896 | 896.0 | 0.0 | 0.0 | The adsorption of proteins on erythrocytes treated with tannic acid and subsequent hemagglutination by antiprotein sera. | S V BOYDEN | J Exp Med | 1951 | 14803635 | Yes |
2926 | 896 | 896.0 | 16.88 | 16.9 | The anaphase promoting complex/cyclosome: a machine designed to destroy. | Jan-Michael Peters | Nat Rev Mol Cell Biol | 2006 | 16896351 | No |
2927 | 7165 | 895.6 | 244.04 | 30.5 | The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. | Ziad S Nasreddine, Natalie A Phillips, Valérie Bédirian, Simon Charbonneau, Victor Whitehead, Isabelle Collin, Jeffrey L Cummings, Howard Chertkow | J Am Geriatr Soc | 2005 | 15817019 | Yes |
2928 | 1791 | 895.5 | 52.6 | 26.3 | The protective effects of estrogen on the cardiovascular system. | M E Mendelsohn, R H Karas | N Engl J Med | 1999 | 10362825 | No |
2929 | 895 | 895.0 | 0.0 | 0.0 | Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig. | G D WINTER | Nature | 1962 | 14007593 | Yes |
2930 | 895 | 895.0 | 0.0 | 0.0 | A simple objective technique for measuring flexibility in thinking. | E A BERG | J Gen Psychol | 1948 | 18889466 | Yes |
2931 | 895 | 895.0 | 23.58 | 23.6 | Principles and challenges of genomewide DNA methylation analysis. | Peter W Laird | Nat Rev Genet | 2010 | 20125086 | No |
2932 | 894 | 894.0 | 23.19 | 23.2 | SETOR: hardware-lighted three-dimensional solid model representations of macromolecules. | S V Evans | J Mol Graph | 1993 | 8347566 | Yes |
2933 | 894 | 894.0 | 0.0 | 0.0 | The reaction of acetylcholine and other carboxylic acid derivatives with hydroxylamine, and its analytical application. | S HESTRIN | J Biol Chem | 1949 | 18133390 | Yes |
2934 | 894 | 894.0 | 24.51 | 24.5 | Transcriptional paradigms in mammalian mitochondrial biogenesis and function. | Richard C Scarpulla | Physiol Rev | 2008 | 18391175 | No |
2935 | 1788 | 894.0 | 67.18 | 33.6 | Insights into the regulation of protein abundance from proteomic and transcriptomic analyses. | Christine Vogel, Edward M Marcotte | Nat Rev Genet | 2012 | 22411467 | No |
2936 | 1787 | 893.5 | 0.0 | 0.0 | A protein sequenator. | P Edman, G Begg | Eur J Biochem | 1967 | 6059350 | Yes |
2937 | 1786 | 893.0 | 84.98 | 42.5 | Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. | H Esterbauer, K H Cheeseman | Methods Enzymol | 1990 | 2233308 | Yes |
2938 | 893 | 893.0 | 29.17 | 29.2 | Pharmacology of cannabinoid CB1 and CB2 receptors. | R G Pertwee | Pharmacol Ther | 1997 | 9336020 | No |
2939 | 1785 | 892.5 | 0.0 | 0.0 | Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells. | A Fabiato, F Fabiato | J Physiol (Paris) | 1979 | 533865 | Yes |
2940 | 1785 | 892.5 | 71.48 | 35.7 | Role of oxidized low density lipoprotein in atherogenesis. | J L Witztum, D Steinberg | J Clin Invest | 1991 | 1752940 | No |
2941 | 892 | 892.0 | 0.0 | 0.0 | Sodium ions, calcium ions, blood pressure regulation, and hypertension: a reassessment and a hypothesis. | M P Blaustein | Am J Physiol | 1977 | 324293 | No |
2942 | 1784 | 892.0 | 45.55 | 22.8 | A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli. | C S Hoffman, F Winston | Gene | 1987 | 3319781 | Yes |
2943 | 892 | 892.0 | 56.52 | 56.5 | A "rationalized" arcsine transform. | G A Studebaker | J Speech Hear Res | 1985 | 4046587 | Yes |
2944 | 1784 | 892.0 | 0.0 | 0.0 | Enzyme-linked immunosorbent assay, Elisa. 3. Quantitation of specific antibodies by enzyme-labeled anti-immunoglobulin in antigen-coated tubes. | E Engvall, P Perlmann | J Immunol | 1972 | 4113792 | Yes |
2945 | 892 | 892.0 | 29.02 | 29.0 | Presynaptic nicotinic ACh receptors. | S Wonnacott | Trends Neurosci | 1997 | 9023878 | No |
2946 | 892 | 892.0 | 39.03 | 39.0 | A review of psychological risk factors in back and neck pain. | S J Linton | Spine (Phila Pa 1976) | 2000 | 10788861 | No |
2947 | 892 | 892.0 | 36.81 | 36.8 | How stigma interferes with mental health care. | Patrick Corrigan | Am Psychol | 2004 | 15491256 | Yes |
2948 | 3565 | 891.2 | 235.32 | 58.8 | IQ-TREE: a fast and effective stochastic algorithm for estimating maximum-likelihood phylogenies. | Lam-Tung Nguyen, Heiko A Schmidt, Arndt von Haeseler, Bui Quang Minh | Mol Biol Evol | 2015 | 25371430 | Yes |
2949 | 891 | 891.0 | 31.36 | 31.4 | Animal mitochondrial DNA: structure and evolution. | D R Wolstenholme | Int Rev Cytol | 1992 | 1452431 | No |
2950 | 891 | 891.0 | 23.46 | 23.5 | Signal transduction via the MAP kinases: proceed at your own RSK. | J Blenis | Proc Natl Acad Sci U S A | 1993 | 8392180 | No |
2951 | 891 | 891.0 | 23.23 | 23.2 | Natural history of chronic hepatitis C. | Leonard B Seeff | Hepatology | 2002 | 12407575 | No |
2952 | 891 | 891.0 | 28.98 | 29.0 | A toxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors. | Ron Hardman | Environ Health Perspect | 2006 | 16451849 | No |
2953 | 891 | 891.0 | 31.57 | 31.6 | Electrochemical glucose biosensors. | Joseph Wang | Chem Rev | 2008 | 18154363 | No |
2954 | 891 | 891.0 | 0.0 | 0.0 | The generalisation of student's problems when several different population variances are involved. | B L WELCH | Biometrika | 1947 | 20287819 | Yes |
2955 | 891 | 891.0 | 43.64 | 43.6 | A review and synthesis of the first 20 years of PET and fMRI studies of heard speech, spoken language and reading. | Cathy J Price | Neuroimage | 2012 | 22584224 | No |
2956 | 5344 | 890.7 | 157.47 | 26.2 | The capsaicin receptor: a heat-activated ion channel in the pain pathway. | M J Caterina, M A Schumacher, M Tominaga, T A Rosen, J D Levine, D Julius | Nature | 1997 | 9349813 | Yes |
2957 | 1781 | 890.5 | 93.34 | 46.7 | Statistical methods in cancer research. Volume I - The analysis of case-control studies. | N E Breslow, N E Day | IARC Sci Publ | 1980 | 7216345 | Yes |
2958 | 890 | 890.0 | 25.1 | 25.1 | A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor. | J Milbrandt | Science | 1987 | 3672127 | Yes |
2959 | 890 | 890.0 | 26.59 | 26.6 | Supported membranes: scientific and practical applications. | E Sackmann | Science | 1996 | 8539599 | No |
2960 | 890 | 890.0 | 39.73 | 39.7 | Comfortable and maximum walking speed of adults aged 20-79 years: reference values and determinants. | R W Bohannon | Age Ageing | 1997 | 9143432 | Yes |
2961 | 890 | 890.0 | 21.7 | 21.7 | Epstein-Barr virus infection. | J I Cohen | N Engl J Med | 2000 | 10944566 | No |
2962 | 890 | 890.0 | 24.5 | 24.5 | Nitric oxide, oxidants, and protein tyrosine nitration. | Rafael Radi | Proc Natl Acad Sci U S A | 2004 | 15020765 | Yes |
2963 | 1780 | 890.0 | 66.9 | 33.5 | DPARSF: A MATLAB Toolbox for "Pipeline" Data Analysis of Resting-State fMRI. | Yan Chao-Gan, Zang Yu-Feng | Front Syst Neurosci | 2010 | 20577591 | Yes |
2964 | 1779 | 889.5 | 45.37 | 22.7 | Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. | G A Gonzalez, M R Montminy | Cell | 1989 | 2573431 | Yes |
2965 | 889 | 889.0 | 0.0 | 0.0 | Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture. | J A Miller | Cancer Res | 1970 | 4915745 | No |
2966 | 889 | 889.0 | 27.78 | 27.8 | Akaike's information criterion in generalized estimating equations. | W Pan | Biometrics | 2001 | 11252586 | Yes |
2967 | 1778 | 889.0 | 46.42 | 23.2 | Regulation of wound healing by growth factors and cytokines. | Sabine Werner, Richard Grose | Physiol Rev | 2003 | 12843410 | No |
2968 | 889 | 889.0 | 0.0 | 0.0 | A cytoarchitectonic atlas of the spinal cord in the cat. | B REXED | J Comp Neurol | 1954 | 13163236 | Yes |
2969 | 889 | 889.0 | 0.0 | 0.0 | A simple fluorimetric method for the estimation of free 11-hydroxycorticoids in human plasma. | D MATTINGLY | J Clin Pathol | 1962 | 14471419 | Yes |
2970 | 5334 | 889.0 | 129.02 | 21.5 | Obesity is associated with macrophage accumulation in adipose tissue. | Stuart P Weisberg, Daniel McCann, Manisha Desai, Michael Rosenbaum, Rudolph L Leibel, Anthony W Ferrante | J Clin Invest | 2003 | 14679176 | Yes |
2971 | 889 | 889.0 | 22.74 | 22.7 | G-quartets 40 years later: from 5'-GMP to molecular biology and supramolecular chemistry. | Jeffery T Davis | Angew Chem Int Ed Engl | 2004 | 14755695 | No |
2972 | 889 | 889.0 | 48.79 | 48.8 | The use of the Center for Epidemiologic Studies Depression Scale in adolescents and young adults. | L S Radloff | J Youth Adolesc | 1991 | 24265004 | Yes |
2973 | 1777 | 888.5 | 33.13 | 16.6 | An extensive class of small RNAs in Caenorhabditis elegans. | R C Lee, V Ambros | Science | 2001 | 11679672 | Yes |
2974 | 1777 | 888.5 | 36.59 | 18.3 | AP-1 as a regulator of cell life and death. | Eitan Shaulian, Michael Karin | Nat Cell Biol | 2002 | 11988758 | No |
2975 | 2665 | 888.3 | 0.0 | 0.0 | Depression: a new animal model sensitive to antidepressant treatments. | R D Porsolt, M Le Pichon, M Jalfre | Nature | 1977 | 559941 | Yes |
2976 | 888 | 888.0 | 54.39 | 54.4 | Analysis of Fickian and non-Fickian drug release from polymers. | N A Peppas | Pharm Acta Helv | 1985 | 4011621 | Yes |
2977 | 2664 | 888.0 | 120.82 | 40.3 | Neighborhoods and violent crime: a multilevel study of collective efficacy. | R J Sampson, S W Raudenbush, F Earls | Science | 1997 | 9252316 | Yes |
2978 | 1776 | 888.0 | 33.02 | 16.5 | Effective targeted gene 'knockdown' in zebrafish. | A Nasevicius, S C Ekker | Nat Genet | 2000 | 11017081 | Yes |
2979 | 1775 | 887.5 | 32.81 | 16.4 | Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. | W Gu, R G Roeder | Cell | 1997 | 9288740 | Yes |
2980 | 1775 | 887.5 | 62.76 | 31.4 | Physiological time-series analysis using approximate entropy and sample entropy. | J S Richman, J R Moorman | Am J Physiol Heart Circ Physiol | 2000 | 10843903 | Yes |
2981 | 1775 | 887.5 | 0.0 | 0.0 | Brain stem reticular formation and activation of the EEG. | G Moruzzi, H W Magoun | Electroencephalogr Clin Neurophysiol | 1949 | 18421835 | Yes |
2982 | 887 | 887.0 | 0.0 | 0.0 | Transformation of yeast by a replicating hybrid plasmid. | J D Beggs | Nature | 1978 | 357984 | Yes |
2983 | 887 | 887.0 | 27.91 | 27.9 | Linkage strategies for genetically complex traits. I. Multilocus models. | N Risch | Am J Hum Genet | 1990 | 2301392 | Yes |
2984 | 887 | 887.0 | 42.31 | 42.3 | Geriatric Depression Scale. | J A Yesavage | Psychopharmacol Bull | 1988 | 3249773 | Yes |
2985 | 887 | 887.0 | 29.19 | 29.2 | On the utility of P3 amplitude as a measure of processing capacity. | A Kok | Psychophysiology | 2001 | 11352145 | No |
2986 | 1774 | 887.0 | 50.78 | 25.4 | Epidemiology of Parkinson's disease. | Lonneke M L de Lau, Monique M B Breteler | Lancet Neurol | 2006 | 16713924 | No |
2987 | 887 | 887.0 | 29.05 | 29.1 | Species concepts and species delimitation. | Kevin De Queiroz | Syst Biol | 2007 | 18027281 | Yes |
2988 | 887 | 887.0 | 26.45 | 26.4 | TNF-mediated inflammatory disease. | J R Bradley | J Pathol | 2008 | 18161752 | No |
2989 | 887 | 887.0 | 21.61 | 21.6 | Hypoxia, HIF1 and glucose metabolism in the solid tumour. | Nicholas C Denko | Nat Rev Cancer | 2008 | 19143055 | No |
2990 | 1773 | 886.5 | 52.48 | 26.2 | Humans integrate visual and haptic information in a statistically optimal fashion. | Marc O Ernst, Martin S Banks | Nature | 2002 | 11807554 | Yes |
2991 | 4432 | 886.4 | 144.17 | 28.8 | Quantitative assessment of tactile allodynia in the rat paw. | S R Chaplan, F W Bach, J W Pogrel, J M Chung, T L Yaksh | J Neurosci Methods | 1994 | 7990513 | Yes |
2992 | 2659 | 886.3 | 94.63 | 31.5 | Health benefits of physical activity: the evidence. | Darren E R Warburton, Crystal Whitney Nicol, Shannon S D Bredin | CMAJ | 2006 | 16534088 | No |
2993 | 886 | 886.0 | 22.63 | 22.6 | ECM and cell surface proteolysis: regulating cellular ecology. | Z Werb | Cell | 1997 | 9390552 | No |
2994 | 886 | 886.0 | 32.66 | 32.7 | Spatially heterogeneous dynamics in supercooled liquids. | M D Ediger | Annu Rev Phys Chem | 2000 | 11031277 | Yes |
2995 | 886 | 886.0 | 0.0 | 0.0 | Aerobic work capacity in men and women with special reference to age. | I ASTRAND | Acta Physiol Scand Suppl | 1960 | 13794892 | Yes |
2996 | 1771 | 885.5 | 66.26 | 33.1 | The reward circuit: linking primate anatomy and human imaging. | Suzanne N Haber, Brian Knutson | Neuropsychopharmacology | 2010 | 19812543 | No |
2997 | 4427 | 885.4 | 168.34 | 33.7 | Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. | Salim Yusuf, Bertram Pitt, Clarence E Davis, William B Hood, Jay N Cohn | N Engl J Med | 1991 | 2057034 | Yes |
2998 | 2656 | 885.3 | 170.37 | 56.8 | Cross-cultural adaptation of health-related quality of life measures: literature review and proposed guidelines. | F Guillemin, C Bombardier, D Beaton | J Clin Epidemiol | 1993 | 8263569 | No |
2999 | 885 | 885.0 | 17.61 | 17.6 | MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing. | Victor Ambros | Cell | 2003 | 12809598 | No |
3000 | 885 | 885.0 | 19.09 | 19.1 | The evolutionary significance of cis-regulatory mutations. | Gregory A Wray | Nat Rev Genet | 2007 | 17304246 | No |
3001 | 1769 | 884.5 | 0.0 | 0.0 | Chronic catheterization of the spinal subarachnoid space. | T L Yaksh, T A Rudy | Physiol Behav | 1976 | 14677603 | Yes |
3002 | 1769 | 884.5 | 52.03 | 26.0 | Recent developments in the MAFFT multiple sequence alignment program. | Kazutaka Katoh, Hiroyuki Toh | Brief Bioinform | 2008 | 18372315 | Yes |
3003 | 1768 | 884.0 | 75.0 | 37.5 | Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. | A E Czeizel, I Dudás | N Engl J Med | 1992 | 1307234 | Yes |
3004 | 884 | 884.0 | 32.54 | 32.5 | Food reward: brain substrates of wanting and liking. | K C Berridge | Neurosci Biobehav Rev | 1996 | 8622814 | No |
3005 | 884 | 884.0 | 38.84 | 38.8 | Physiological implications of hydrogen sulfide: a whiff exploration that blossomed. | Rui Wang | Physiol Rev | 2012 | 22535897 | No |
3006 | 1767 | 883.5 | 63.56 | 31.8 | Development of a new resilience scale: the Connor-Davidson Resilience Scale (CD-RISC). | Kathryn M Connor, Jonathan R T Davidson | Depress Anxiety | 2003 | 12964174 | Yes |
3007 | 1766 | 883.0 | 0.0 | 0.0 | High resolution acrylamide gel electrophoresis of histones. | S Panyim, R Chalkley | Arch Biochem Biophys | 1969 | 5778650 | Yes |
3008 | 883 | 883.0 | 28.29 | 28.3 | AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function. | D Grahame Hardie | Genes Dev | 2011 | 21937710 | No |
3009 | 1765 | 882.5 | 0.0 | 0.0 | Functions of lysosomes. | C De Duve, R Wattiaux | Annu Rev Physiol | 1966 | 5322983 | No |
3010 | 2647 | 882.3 | 0.0 | 0.0 | Cytochemistry and electron microscopy. The preservation of cellular ultrastructure and enzymatic activity by aldehyde fixation. | D D SABATINI, K BENSCH, R J BARRNETT | J Cell Biol | 1963 | 13975866 | Yes |
3011 | 882 | 882.0 | 56.0 | 56.0 | ROC methodology in radiologic imaging. | C E Metz | Invest Radiol | 1986 | 3095258 | No |
3012 | 882 | 882.0 | 32.03 | 32.0 | Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections. | F Hefti | J Neurosci | 1986 | 3746405 | Yes |
3013 | 2646 | 882.0 | 61.24 | 20.4 | TGF-beta signalling from cell membrane to nucleus through SMAD proteins. | C H Heldin, K Miyazono, P ten Dijke | Nature | 1997 | 9393997 | No |
3014 | 882 | 882.0 | 16.62 | 16.6 | Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. | R A Frye | Biochem Biophys Res Commun | 2000 | 10873683 | Yes |
3015 | 882 | 882.0 | 0.0 | 0.0 | The cytoarchitectonic organization of the spinal cord in the cat. | B REXED | J Comp Neurol | 1952 | 14946260 | Yes |
3016 | 1764 | 882.0 | 37.88 | 18.9 | Convergence of Wnt, beta-catenin, and cadherin pathways. | W James Nelson, Roel Nusse | Science | 2004 | 15001769 | No |
3017 | 1763 | 881.5 | 0.0 | 0.0 | Immunoassay of insulin with insulin-antibody precipitate. | C N HALES, P J RANDLE | Biochem J | 1963 | 13952078 | Yes |
3018 | 1763 | 881.5 | 42.14 | 21.1 | Deep tissue two-photon microscopy. | Fritjof Helmchen, Winfried Denk | Nat Methods | 2005 | 16299478 | No |
3019 | 881 | 881.0 | 21.95 | 21.9 | Molecular mechanisms of myocardial remodeling. | B Swynghedauw | Physiol Rev | 1999 | 9922372 | No |
3020 | 881 | 881.0 | 36.11 | 36.1 | Predictors of postpartum depression: an update. | C T Beck | Nurs Res | 2001 | 11570712 | Yes |
3021 | 1762 | 881.0 | 0.0 | 0.0 | A study of the factors affecting the aluminum oxide-trihydroxyindole procedure for the analysis of catecholamines. | A H ANTON, D F SAYRE | J Pharmacol Exp Ther | 1962 | 14013351 | Yes |
3022 | 1761 | 880.5 | 44.37 | 22.2 | Obesity and insulin resistance. | B B Kahn, J S Flier | J Clin Invest | 2000 | 10953022 | No |
3023 | 1759 | 879.5 | 50.26 | 25.1 | An integrative theory of locus coeruleus-norepinephrine function: adaptive gain and optimal performance. | Gary Aston-Jones, Jonathan D Cohen | Annu Rev Neurosci | 2005 | 16022602 | No |
3024 | 2638 | 879.3 | 87.8 | 29.3 | Regulation of cancer cell metabolism. | Rob A Cairns, Isaac S Harris, Tak W Mak | Nat Rev Cancer | 2011 | 21258394 | No |
3025 | 879 | 879.0 | 35.37 | 35.4 | Selective attention and the organization of visual information. | J Duncan | J Exp Psychol Gen | 1984 | 6240521 | Yes |
3026 | 879 | 879.0 | 23.45 | 23.4 | Amyloid, the presenilins and Alzheimer's disease. | J Hardy | Trends Neurosci | 1997 | 9106355 | No |
3027 | 4393 | 878.6 | 130.32 | 26.1 | Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. | T R Mosmann, H Cherwinski, M W Bond, M A Giedlin, R L Coffman | J Immunol | 1986 | 2419430 | Yes |
3028 | 878 | 878.0 | 0.0 | 0.0 | Fundamental patterns of knowing in nursing. | B Carper | ANS Adv Nurs Sci | 1978 | 110216 | Yes |
3029 | 1756 | 878.0 | 0.0 | 0.0 | Solubilization of membranes by detergents. | A Helenius, K Simons | Biochim Biophys Acta | 1975 | 1091302 | No |
3030 | 878 | 878.0 | 28.39 | 28.4 | Aging, energy, and oxidative stress in neurodegenerative diseases. | M F Beal | Ann Neurol | 1995 | 7668820 | No |
3031 | 2634 | 878.0 | 56.4 | 18.8 | Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. | Paola Scaffidi, Tom Misteli, Marco E Bianchi | Nature | 2002 | 12110890 | Yes |
3032 | 1756 | 878.0 | 54.63 | 27.3 | Fitness effects on the cognitive function of older adults: a meta-analytic study. | Stanley Colcombe, Arthur F Kramer | Psychol Sci | 2003 | 12661673 | Yes |
3033 | 878 | 878.0 | 25.09 | 25.1 | Pathogenesis of osteoporosis: concepts, conflicts, and prospects. | Lawrence G Raisz | J Clin Invest | 2005 | 16322775 | No |
3034 | 878 | 878.0 | 26.64 | 26.6 | N-heterocyclic carbenes: a new concept in organometallic catalysis. | Wolfgang A Herrmann | Angew Chem Int Ed Engl | 2002 | 19750753 | Yes |
3035 | 7901 | 877.9 | 231.52 | 25.7 | Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. | Cole Trapnell, Brian A Williams, Geo Pertea, Ali Mortazavi, Gordon Kwan, Marijke J van Baren, Steven L Salzberg, Barbara J Wold, Lior Pachter | Nat Biotechnol | 2010 | 20436464 | Yes |
3036 | 1755 | 877.5 | 36.96 | 18.5 | Rho GTPases and signaling networks. | L Van Aelst, C D'Souza-Schorey | Genes Dev | 1997 | 9308960 | No |
3037 | 1754 | 877.0 | 0.0 | 0.0 | Theoretical aspects of DNA-protein interactions: co-operative and non-co-operative binding of large ligands to a one-dimensional homogeneous lattice. | J D McGhee, P H von Hippel | J Mol Biol | 1974 | 4416620 | Yes |
3038 | 877 | 877.0 | 22.35 | 22.4 | Translating cell biology into therapeutic advances in Alzheimer's disease. | D J Selkoe | Nature | 1999 | 10392577 | No |
3039 | 877 | 877.0 | 33.8 | 33.8 | Apoptosis in cancer: from pathogenesis to treatment. | Rebecca S Y Wong | J Exp Clin Cancer Res | 2011 | 21943236 | No |
3040 | 877 | 877.0 | 51.43 | 51.4 | A comprehensive review on metabolic syndrome. | Jaspinder Kaur | Cardiol Res Pract | 2014 | 24711954 | No |
3041 | 1752 | 876.0 | 76.45 | 38.2 | Pharmaceuticals and personal care products in the environment: agents of subtle change? | C G Daughton, T A Ternes | Environ Health Perspect | 1999 | 10592150 | No |
3042 | 876 | 876.0 | 24.92 | 24.9 | Formation and function of the myofibroblast during tissue repair. | Boris Hinz | J Invest Dermatol | 2007 | 17299435 | No |
3043 | 876 | 876.0 | 23.43 | 23.4 | Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. | Thomas A Wynn | J Clin Invest | 2007 | 17332879 | No |
3044 | 1752 | 876.0 | 45.86 | 22.9 | Establishing, maintaining and modifying DNA methylation patterns in plants and animals. | Julie A Law, Steven E Jacobsen | Nat Rev Genet | 2010 | 20142834 | No |
3045 | 1751 | 875.5 | 67.62 | 33.8 | Origins and evolution of antibiotic resistance. | Julian Davies, Dorothy Davies | Microbiol Mol Biol Rev | 2010 | 20805405 | No |
3046 | 875 | 875.0 | 0.0 | 0.0 | Renin-angiotensin system: biochemistry and mechanisms of action. | M J Peach | Physiol Rev | 1977 | 191856 | No |
3047 | 1750 | 875.0 | 42.58 | 21.3 | Multiple nuclear factors interact with the immunoglobulin enhancer sequences. | R Sen, D Baltimore | Cell | 1986 | 3091258 | Yes |
3048 | 875 | 875.0 | 57.34 | 57.3 | New norms of upper limb fat and muscle areas for assessment of nutritional status. | A R Frisancho | Am J Clin Nutr | 1981 | 6975564 | Yes |
3049 | 875 | 875.0 | 28.75 | 28.8 | Venous thrombosis: a multicausal disease. | F R Rosendaal | Lancet | 1999 | 10209995 | No |
3050 | 875 | 875.0 | 18.3 | 18.3 | Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins. | M D Resh | Biochim Biophys Acta | 1999 | 10446384 | No |
3051 | 875 | 875.0 | 15.29 | 15.3 | T cell anergy. | Ronald H Schwartz | Annu Rev Immunol | 2003 | 12471050 | No |
3052 | 2625 | 875.0 | 76.57 | 25.5 | Use and abuse of HOMA modeling. | Tara M Wallace, Jonathan C Levy, David R Matthews | Diabetes Care | 2004 | 15161807 | No |
3053 | 7872 | 874.7 | 245.55 | 27.3 | MolProbity: all-atom structure validation for macromolecular crystallography. | Vincent B Chen, W Bryan Arendall, Jeffrey J Headd, Daniel A Keedy, Robert M Immormino, Gary J Kapral, Laura W Murray, Jane S Richardson, David C Richardson | Acta Crystallogr D Biol Crystallogr | 2010 | 20057044 | Yes |
3054 | 874 | 874.0 | 25.41 | 25.4 | Neuropathology of Parkinson's disease. | L S Forno | J Neuropathol Exp Neurol | 1996 | 8786384 | No |
3055 | 874 | 874.0 | 15.34 | 15.3 | SCF and Cullin/Ring H2-based ubiquitin ligases. | R J Deshaies | Annu Rev Cell Dev Biol | 1999 | 10611969 | No |
3056 | 1748 | 874.0 | 40.68 | 20.3 | InterProScan--an integration platform for the signature-recognition methods in InterPro. | E M Zdobnov, R Apweiler | Bioinformatics | 2001 | 11590104 | Yes |
3057 | 874 | 874.0 | 24.03 | 24.0 | Context, ambiguity, and unlearning: sources of relapse after behavioral extinction. | Mark E Bouton | Biol Psychiatry | 2002 | 12437938 | No |
3058 | 874 | 874.0 | 0.0 | 0.0 | The diagnosis of ischaemic heart pain and intermittent claudication in field surveys. | G A ROSE | Bull World Health Organ | 1962 | 13974778 | Yes |
3059 | 874 | 874.0 | 26.89 | 26.9 | Production and scavenging of reactive oxygen species in chloroplasts and their functions. | Kozi Asada | Plant Physiol | 2006 | 16760493 | Yes |
3060 | 874 | 874.0 | 0.0 | 0.0 | An approximate distribution of estimates of variance components. | F E SATTERTHWAITE | Biometrics | 1946 | 20287815 | Yes |
3061 | 1747 | 873.5 | 80.45 | 40.2 | Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry. | A I Basbaum, H L Fields | Annu Rev Neurosci | 1984 | 6143527 | No |
3062 | 873 | 873.0 | 26.9 | 26.9 | Molecular drive: a cohesive mode of species evolution. | G Dover | Nature | 1982 | 7110332 | Yes |
3063 | 873 | 873.0 | 19.37 | 19.4 | [URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae. | R B Wickner | Science | 1994 | 7909170 | No |
3064 | 873 | 873.0 | 32.85 | 32.9 | Low-molecular-weight heparins. | J I Weitz | N Engl J Med | 1997 | 9278467 | No |
3065 | 1746 | 873.0 | 37.87 | 18.9 | A survey of telomerase activity in human cancer. | J W Shay, S Bacchetti | Eur J Cancer | 1997 | 9282118 | No |
3066 | 873 | 873.0 | 21.51 | 21.5 | r8s: inferring absolute rates of molecular evolution and divergence times in the absence of a molecular clock. | Michael J Sanderson | Bioinformatics | 2003 | 12538260 | Yes |
3067 | 873 | 873.0 | 0.0 | 0.0 | Nutrition needs of mammalian cells in tissue culture. | H EAGLE | Science | 1955 | 13255879 | Yes |
3068 | 1745 | 872.5 | 49.62 | 24.8 | Adipocytokines: mediators linking adipose tissue, inflammation and immunity. | Herbert Tilg, Alexander R Moschen | Nat Rev Immunol | 2006 | 16998510 | No |
3069 | 872 | 872.0 | 19.71 | 19.7 | Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes. | D Hanahan | Nature | 1985 | 2986015 | Yes |
3070 | 872 | 872.0 | 15.79 | 15.8 | Roles of the NKG2D immunoreceptor and its ligands. | David H Raulet | Nat Rev Immunol | 2003 | 14523385 | No |
3071 | 872 | 872.0 | 17.1 | 17.1 | Dendritic-cell control of pathogen-driven T-cell polarization. | Martien L Kapsenberg | Nat Rev Immunol | 2003 | 14647480 | No |
3072 | 872 | 872.0 | 22.11 | 22.1 | Viruses in the sea. | Curtis A Suttle | Nature | 2005 | 16163346 | No |
3073 | 2616 | 872.0 | 76.0 | 25.3 | The widespread regulation of microRNA biogenesis, function and decay. | Jacek Krol, Inga Loedige, Witold Filipowicz | Nat Rev Genet | 2010 | 20661255 | No |
3074 | 1743 | 871.5 | 130.8 | 65.4 | The amyloid hypothesis of Alzheimer's disease at 25 years. | Dennis J Selkoe, John Hardy | EMBO Mol Med | 2016 | 27025652 | No |
3075 | 871 | 871.0 | 30.79 | 30.8 | Qinghaosu (artemisinin): an antimalarial drug from China. | D L Klayman | Science | 1985 | 3887571 | No |
3076 | 871 | 871.0 | 0.0 | 0.0 | Displaced proximal humeral fractures. I. Classification and evaluation. | C S Neer | J Bone Joint Surg Am | 1970 | 5455339 | Yes |
3077 | 1742 | 871.0 | 39.54 | 19.8 | IAP family proteins--suppressors of apoptosis. | Q L Deveraux, J C Reed | Genes Dev | 1999 | 9990849 | No |
3078 | 871 | 871.0 | 21.84 | 21.8 | A cortical-hippocampal system for declarative memory. | H Eichenbaum | Nat Rev Neurosci | 2000 | 11252767 | No |
3079 | 2612 | 870.7 | 106.55 | 35.5 | The 'Trier Social Stress Test'--a tool for investigating psychobiological stress responses in a laboratory setting. | C Kirschbaum, K M Pirke, D H Hellhammer | Neuropsychobiology | 1993 | 8255414 | Yes |
3080 | 5224 | 870.7 | 154.82 | 25.8 | Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. | S Yusuf, P Sleight, J Pogue, J Bosch, R Davies, G Dagenais | N Engl J Med | 2000 | 10639539 | Yes |
3081 | 1741 | 870.5 | 36.29 | 18.1 | The druggable genome. | Andrew L Hopkins, Colin R Groom | Nat Rev Drug Discov | 2002 | 12209152 | No |
3082 | 5221 | 870.2 | 158.06 | 26.3 | Ghrelin is a growth-hormone-releasing acylated peptide from stomach. | M Kojima, H Hosoda, Y Date, M Nakazato, H Matsuo, K Kangawa | Nature | 1999 | 10604470 | Yes |
3083 | 870 | 870.0 | 31.1 | 31.1 | Cytochrome oxidase: an endogenous metabolic marker for neuronal activity. | M T Wong-Riley | Trends Neurosci | 1989 | 2469224 | No |
3084 | 870 | 870.0 | 31.74 | 31.7 | Fibronectin and its receptors. | E Ruoslahti | Annu Rev Biochem | 1988 | 2972252 | No |
3085 | 870 | 870.0 | 35.78 | 35.8 | Protein damage and degradation by oxygen radicals. I. general aspects. | K J Davies | J Biol Chem | 1987 | 3036875 | Yes |
3086 | 870 | 870.0 | 46.79 | 46.8 | How is the level of free arachidonic acid controlled in mammalian cells? | R F Irvine | Biochem J | 1982 | 6810878 | No |
3087 | 870 | 870.0 | 24.94 | 24.9 | Cells in stress: transcriptional activation of heat shock genes. | R I Morimoto | Science | 1993 | 8451637 | No |
3088 | 870 | 870.0 | 21.85 | 21.9 | The neurobiology of consolidations, or, how stable is the engram? | Yadin Dudai | Annu Rev Psychol | 2004 | 14744210 | No |
3089 | 870 | 870.0 | 26.68 | 26.7 | Thermo- and pH-responsive polymers in drug delivery. | Dirk Schmaljohann | Adv Drug Deliv Rev | 2006 | 17125884 | No |
3090 | 869 | 869.0 | 19.99 | 20.0 | Cytokine receptor signalling. | J N Ihle | Nature | 1995 | 7566171 | No |
3091 | 3476 | 869.0 | 96.08 | 24.0 | Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter. | L M Guzman, D Belin, M J Carson, J Beckwith | J Bacteriol | 1995 | 7608087 | Yes |
3092 | 869 | 869.0 | 34.26 | 34.3 | Sensorimotor integration in human postural control. | R J Peterka | J Neurophysiol | 2002 | 12205132 | Yes |
3093 | 1737 | 868.5 | 63.66 | 31.8 | Nitric oxide synthases in mammals. | R G Knowles, S Moncada | Biochem J | 1994 | 7510950 | No |
3094 | 1737 | 868.5 | 61.44 | 30.7 | Strategies in the design of nanoparticles for therapeutic applications. | Robby A Petros, Joseph M DeSimone | Nat Rev Drug Discov | 2010 | 20616808 | No |
3095 | 868 | 868.0 | 0.0 | 0.0 | Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction. | J R David | Proc Natl Acad Sci U S A | 1966 | 5229858 | Yes |
3096 | 868 | 868.0 | 23.15 | 23.1 | Atherosclerosis is an inflammatory disease. | R Ross | Am Heart J | 1999 | 10539839 | No |
3097 | 868 | 868.0 | 21.77 | 21.8 | A likelihood approach to estimating phylogeny from discrete morphological character data. | P O Lewis | Syst Biol | 2001 | 12116640 | Yes |
3098 | 868 | 868.0 | 21.28 | 21.3 | The state of lipid rafts: from model membranes to cells. | Michael Edidin | Annu Rev Biophys Biomol Struct | 2003 | 12543707 | No |
3099 | 868 | 868.0 | 25.92 | 25.9 | A theory of magnitude: common cortical metrics of time, space and quantity. | Vincent Walsh | Trends Cogn Sci | 2003 | 14585444 | Yes |
3100 | 868 | 868.0 | 33.87 | 33.9 | Thermal properties of graphene and nanostructured carbon materials. | Alexander A Balandin | Nat Mater | 2011 | 21778997 | Yes |
3101 | 3469 | 867.2 | 106.1 | 26.5 | Real time quantitative PCR. | C A Heid, J Stevens, K J Livak, P M Williams | Genome Res | 1996 | 8908518 | Yes |
3102 | 1734 | 867.0 | 37.08 | 18.5 | AMPA receptor trafficking and synaptic plasticity. | Roberto Malinow, Robert C Malenka | Annu Rev Neurosci | 2002 | 12052905 | No |
3103 | 867 | 867.0 | 17.16 | 17.2 | DNA methylation in cancer: too much, but also too little. | Melanie Ehrlich | Oncogene | 2002 | 12154403 | No |
3104 | 867 | 867.0 | 0.0 | 0.0 | A production of amino acids under possible primitive earth conditions. | S L MILLER | Science | 1953 | 13056598 | Yes |
3105 | 867 | 867.0 | 24.68 | 24.7 | Targeting DNA topoisomerase II in cancer chemotherapy. | John L Nitiss | Nat Rev Cancer | 2009 | 19377506 | No |
3106 | 866 | 866.0 | 21.02 | 21.0 | Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture. | H E Ruley | Nature | 1983 | 6308473 | Yes |
3107 | 866 | 866.0 | 29.28 | 29.3 | Ion suppression in mass spectrometry. | Thomas M Annesley | Clin Chem | 2003 | 12816898 | No |
3108 | 1732 | 866.0 | 37.38 | 18.7 | Of mice and not men: differences between mouse and human immunology. | Javier Mestas, Christopher C W Hughes | J Immunol | 2004 | 14978070 | No |
3109 | 866 | 866.0 | 19.23 | 19.2 | Models, mechanisms and clinical evidence for cancer dormancy. | Julio A Aguirre-Ghiso | Nat Rev Cancer | 2007 | 17957189 | No |
3110 | 866 | 866.0 | 21.07 | 21.1 | The tumor microenvironment and its role in promoting tumor growth. | T L Whiteside | Oncogene | 2008 | 18836471 | No |
3111 | 2597 | 865.7 | 137.64 | 45.9 | Measurement of health status. Ascertaining the minimal clinically important difference. | R Jaeschke, J Singer, G H Guyatt | Control Clin Trials | 1989 | 2691207 | Yes |
3112 | 1731 | 865.5 | 0.0 | 0.0 | A method of trace iodination of proteins for immunologic studies. | P J McConahey, F J Dixon | Int Arch Allergy Appl Immunol | 1966 | 4160044 | Yes |
3113 | 865 | 865.0 | 21.53 | 21.5 | At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells. | M Kozak | J Mol Biol | 1987 | 3681984 | Yes |
3114 | 865 | 865.0 | 33.59 | 33.6 | Peritonectomy procedures. | P H Sugarbaker | Ann Surg | 1995 | 7826158 | Yes |
3115 | 865 | 865.0 | 28.29 | 28.3 | Synchronization of cortical activity and its putative role in information processing and learning. | W Singer | Annu Rev Physiol | 1993 | 8466179 | No |
3116 | 865 | 865.0 | 36.34 | 36.3 | Socioeconomic disadvantage and child development. | V C McLoyd | Am Psychol | 1998 | 9491747 | No |
3117 | 865 | 865.0 | 27.4 | 27.4 | Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. | Michael F Holick | Am J Clin Nutr | 2004 | 14985208 | No |
3118 | 865 | 865.0 | 28.94 | 28.9 | Targeting recovery: priorities of the spinal cord-injured population. | Kim D Anderson | J Neurotrauma | 2004 | 15672628 | Yes |
3119 | 865 | 865.0 | 17.43 | 17.4 | RNA regulons: coordination of post-transcriptional events. | Jack D Keene | Nat Rev Genet | 2007 | 17572691 | No |
3120 | 865 | 865.0 | 33.13 | 33.1 | Clinical practice. Endometriosis. | Linda C Giudice | N Engl J Med | 2010 | 20573927 | No |
3121 | 2594 | 864.7 | 77.41 | 25.8 | Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. | M K Parmar, V Torri, L Stewart | Stat Med | 1998 | 9921604 | Yes |
3122 | 1729 | 864.5 | 56.23 | 28.1 | The capacity of visual working memory for features and conjunctions. | S J Luck, E K Vogel | Nature | 1997 | 9384378 | Yes |
3123 | 864 | 864.0 | 67.91 | 67.9 | A method of analysing interview transcripts in qualitative research. | P Burnard | Nurse Educ Today | 1991 | 1775125 | Yes |
3124 | 864 | 864.0 | 42.98 | 43.0 | A spreading-activation theory of retrieval in sentence production. | G S Dell | Psychol Rev | 1986 | 3749399 | Yes |
3125 | 864 | 864.0 | 53.67 | 53.7 | Coping theory and research: past, present, and future. | R S Lazarus | Psychosom Med | 1993 | 8346332 | No |
3126 | 1728 | 864.0 | 83.63 | 41.8 | Cronbach's alpha. | J M Bland, D G Altman | BMJ | 1997 | 9055718 | Yes |
3127 | 864 | 864.0 | 24.58 | 24.6 | PHOTOPROTECTION REVISITED: Genetic and Molecular Approaches. | Krishna K. Niyogi | Annu Rev Plant Physiol Plant Mol Biol | 1999 | 15012213 | Yes |
3128 | 864 | 864.0 | 21.04 | 21.0 | The integration of macromolecular diffraction data. | Andrew G W Leslie | Acta Crystallogr D Biol Crystallogr | 2006 | 16369093 | No |
3129 | 864 | 864.0 | 24.68 | 24.7 | Dengue. | Scott B Halstead | Lancet | 2007 | 17993365 | No |
3130 | 1727 | 863.5 | 47.09 | 23.5 | Quorum sensing: cell-to-cell communication in bacteria. | Christopher M Waters, Bonnie L Bassler | Annu Rev Cell Dev Biol | 2005 | 16212498 | No |
3131 | 2589 | 863.0 | 114.66 | 38.2 | Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. | P S Walsh, D A Metzger, R Higuchi | Biotechniques | 1991 | 1867860 | Yes |
3132 | 863 | 863.0 | 0.0 | 0.0 | Evaluation of a mental test score for assessment of mental impairment in the elderly. | H M Hodkinson | Age Ageing | 1972 | 4669880 | Yes |
3133 | 863 | 863.0 | 19.72 | 19.7 | Twilight zone of protein sequence alignments. | B Rost | Protein Eng | 1999 | 10195279 | Yes |
3134 | 863 | 863.0 | 0.0 | 0.0 | ELECTRON MICROSCOPE STUDIES ON THE STRUCTURE OF NATURAL AND SYNTHETIC PROTEIN FILAMENTS FROM STRIATED MUSCLE. | H E HUXLEY | J Mol Biol | 1963 | 14064165 | Yes |
3135 | 863 | 863.0 | 28.99 | 29.0 | Regulation of glutathione synthesis. | Shelly C Lu | Mol Aspects Med | 2009 | 18601945 | No |
3136 | 1725 | 862.5 | 57.78 | 28.9 | The spread of obesity in a large social network over 32 years. | Nicholas A Christakis, James H Fowler | N Engl J Med | 2007 | 17652652 | Yes |
3137 | 862 | 862.0 | 0.0 | 0.0 | Avidin. | N M Green | Adv Protein Chem | 1975 | 237414 | Yes |
3138 | 1724 | 862.0 | 39.13 | 19.6 | Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin. | J J Skehel, D C Wiley | Annu Rev Biochem | 2000 | 10966468 | No |
3139 | 862 | 862.0 | 22.94 | 22.9 | Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms. | William C Aird | Circ Res | 2007 | 17272818 | No |
3140 | 1723 | 861.5 | 0.0 | 0.0 | A rating scale for extrapyramidal side effects. | G M Simpson, J W Angus | Acta Psychiatr Scand Suppl | 1970 | 4917967 | Yes |
3141 | 1723 | 861.5 | 37.66 | 18.8 | Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm. | P E Wright, H J Dyson | J Mol Biol | 1999 | 10550212 | No |
3142 | 1722 | 861.0 | 72.85 | 36.4 | Social conditions as fundamental causes of disease. | B G Link, J Phelan | J Health Soc Behav | 1995 | 7560851 | No |
3143 | 861 | 861.0 | 34.23 | 34.2 | Strategies of antioxidant defense. | H Sies | Eur J Biochem | 1993 | 7688300 | No |
3144 | 1722 | 861.0 | 46.13 | 23.1 | Endometriosis. | Linda C Giudice, Lee C Kao | Lancet | 2004 | 15541453 | No |
3145 | 861 | 861.0 | 19.14 | 19.1 | Understanding the odd science of aging. | Thomas B L Kirkwood | Cell | 2005 | 15734677 | No |
3146 | 1721 | 860.5 | 43.55 | 21.8 | Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. | Daniel J Hicklin, Lee M Ellis | J Clin Oncol | 2005 | 15585754 | No |
3147 | 1721 | 860.5 | 43.91 | 22.0 | The host defense of Drosophila melanogaster. | Bruno Lemaitre, Jules Hoffmann | Annu Rev Immunol | 2007 | 17201680 | No |
3148 | 860 | 860.0 | 33.95 | 34.0 | Computer programs for calculating total from specified free or free from specified total ionic concentrations in aqueous solutions containing multiple metals and ligands. | A Fabiato | Methods Enzymol | 1988 | 3231093 | Yes |
3149 | 1720 | 860.0 | 59.74 | 29.9 | Heterogeneous photocatalyst materials for water splitting. | Akihiko Kudo, Yugo Miseki | Chem Soc Rev | 2009 | 19088977 | Yes |
3150 | 1719 | 859.5 | 62.53 | 31.3 | A novel suicide vector and its use in construction of insertion mutations: osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR. | V L Miller, J J Mekalanos | J Bacteriol | 1988 | 2836362 | Yes |
3151 | 1719 | 859.5 | 0.0 | 0.0 | Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms. | R J Britten, D E Kohne | Science | 1968 | 4874239 | Yes |
3152 | 2578 | 859.3 | 80.96 | 27.0 | Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. | Robert G Hart, Lesly A Pearce, Maria I Aguilar | Ann Intern Med | 2007 | 17577005 | Yes |
3153 | 859 | 859.0 | 21.23 | 21.2 | Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy. | R H Schwartz | Cell | 1992 | 1335362 | No |
3154 | 859 | 859.0 | 42.59 | 42.6 | Gait changes in older adults: predictors of falls or indicators of fear. | B E Maki | J Am Geriatr Soc | 1997 | 9063277 | Yes |
3155 | 859 | 859.0 | 23.2 | 23.2 | Metagenomics: application of genomics to uncultured microorganisms. | Jo Handelsman | Microbiol Mol Biol Rev | 2004 | 15590779 | No |
3156 | 859 | 859.0 | 18.71 | 18.7 | Nonlinear structured-illumination microscopy: wide-field fluorescence imaging with theoretically unlimited resolution. | Mats G L Gustafsson | Proc Natl Acad Sci U S A | 2005 | 16141335 | Yes |
3157 | 859 | 859.0 | 26.58 | 26.6 | Neuronal gamma-band synchronization as a fundamental process in cortical computation. | Pascal Fries | Annu Rev Neurosci | 2009 | 19400723 | No |
3158 | 859 | 859.0 | 38.29 | 38.3 | The role of senescent cells in ageing. | Jan M van Deursen | Nature | 2014 | 24848057 | No |
3159 | 859 | 859.0 | 81.88 | 81.9 | Understanding Bland Altman analysis. | Davide Giavarina | Biochem Med (Zagreb) | 2015 | 26110027 | No |
3160 | 1717 | 858.5 | 61.08 | 30.5 | Multiple significance tests: the Bonferroni method. | J M Bland, D G Altman | BMJ | 1995 | 7833759 | Yes |
3161 | 3434 | 858.5 | 110.8 | 27.7 | Biological identifications through DNA barcodes. | Paul D N Hebert, Alina Cywinska, Shelley L Ball, Jeremy R deWaard | Proc Biol Sci | 2003 | 12614582 | Yes |
3162 | 858 | 858.0 | 0.0 | 0.0 | Evolution of ageing. | T B Kirkwood | Nature | 1977 | 593350 | Yes |
3163 | 2574 | 858.0 | 57.57 | 19.2 | Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. | E Li, T H Bestor, R Jaenisch | Cell | 1992 | 1606615 | Yes |
3164 | 858 | 858.0 | 28.86 | 28.9 | Comparing evolvability and variability of quantitative traits. | D Houle | Genetics | 1992 | 1732160 | Yes |
3165 | 858 | 858.0 | 46.94 | 46.9 | Bacterial adherence: adhesin-receptor interactions mediating the attachment of bacteria to mucosal surface. | E H Beachey | J Infect Dis | 1981 | 7014727 | No |
3166 | 858 | 858.0 | 29.38 | 29.4 | Microbial heavy-metal resistance. | D H Nies | Appl Microbiol Biotechnol | 1999 | 10422221 | No |
3167 | 1716 | 858.0 | 0.0 | 0.0 | Construct validity in psychological tests. | L J CRONBACH, P E MEEHL | Psychol Bull | 1955 | 13245896 | Yes |
3168 | 858 | 858.0 | 0.0 | 0.0 | Agammaglobulinemia. | O C BRUTON | Pediatrics | 1952 | 14929630 | Yes |
3169 | 2574 | 858.0 | 67.03 | 22.3 | Obesity induces a phenotypic switch in adipose tissue macrophage polarization. | Carey N Lumeng, Jennifer L Bodzin, Alan R Saltiel | J Clin Invest | 2007 | 17200717 | Yes |
3170 | 1716 | 858.0 | 55.85 | 27.9 | Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. | Amit Etkin, Tor D Wager | Am J Psychiatry | 2007 | 17898336 | Yes |
3171 | 2572 | 857.3 | 55.47 | 18.5 | Computer visualization of three-dimensional image data using IMOD. | J R Kremer, D N Mastronarde, J R McIntosh | J Struct Biol | 1996 | 8742726 | Yes |
3172 | 1714 | 857.0 | 0.0 | 0.0 | Epidermal growth factor. | G Carpenter, S Cohen | Annu Rev Biochem | 1979 | 382984 | No |
3173 | 857 | 857.0 | 23.09 | 23.1 | Cadherins: a molecular family important in selective cell-cell adhesion. | M Takeichi | Annu Rev Biochem | 1990 | 2197976 | No |
3174 | 857 | 857.0 | 0.0 | 0.0 | Stereochemical criteria for polypeptides and proteins. V. Conformation of a system of three linked peptide units. | C M Venkatachalam | Biopolymers | 1968 | 5685102 | Yes |
3175 | 857 | 857.0 | 24.25 | 24.2 | Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes: a proposal for a synonymous codon choice that is optimal for the E. coli translational system. | T Ikemura | J Mol Biol | 1981 | 6175758 | Yes |
3176 | 857 | 857.0 | 42.89 | 42.9 | Glutathione peroxidase. | A Wendel | Methods Enzymol | 1981 | 7329310 | Yes |
3177 | 857 | 857.0 | 0.0 | 0.0 | A modified procedure for lead staining of thin sections. | G MILLONIG | J Biophys Biochem Cytol | 1961 | 14474176 | Yes |
3178 | 857 | 857.0 | 21.67 | 21.7 | Liver regeneration. | George K Michalopoulos | J Cell Physiol | 2007 | 17559071 | No |
3179 | 856 | 856.0 | 0.0 | 0.0 | An approach for the treatment of penile carcinoma. | R M Cabanas | Cancer | 1977 | 837331 | Yes |
3180 | 2568 | 856.0 | 80.43 | 26.8 | Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). | R S Spielman, R E McGinnis, W J Ewens | Am J Hum Genet | 1993 | 8447318 | Yes |
3181 | 856 | 856.0 | 25.01 | 25.0 | Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. | G Boden | Diabetes | 1997 | 8971073 | No |
3182 | 856 | 856.0 | 25.04 | 25.0 | Mode of action of membrane active antimicrobial peptides. | Yechiel Shai | Biopolymers | 2002 | 12491537 | No |
3183 | 856 | 856.0 | 27.55 | 27.6 | Invited review: Aging and sarcopenia. | Timothy J Doherty | J Appl Physiol (1985) | 2003 | 12970377 | No |
3184 | 856 | 856.0 | 33.53 | 33.5 | The World Health Report 2006: working together for health. | J-J Guilbert | Educ Health (Abingdon) | 2006 | 17178522 | Yes |
3185 | 1711 | 855.5 | 0.0 | 0.0 | Calcium-dependent bacteriophage DNA infection. | M Mandel, A Higa | J Mol Biol | 1970 | 4922220 | Yes |
3186 | 855 | 855.0 | 41.27 | 41.3 | Infection by verocytotoxin-producing Escherichia coli. | M A Karmali | Clin Microbiol Rev | 1989 | 2644022 | No |
3187 | 855 | 855.0 | 18.72 | 18.7 | The Sp-family of transcription factors. | G Suske | Gene | 1999 | 10570957 | No |
3188 | 855 | 855.0 | 17.8 | 17.8 | Targeting death and decoy receptors of the tumour-necrosis factor superfamily. | Avi Ashkenazi | Nat Rev Cancer | 2002 | 12189384 | No |
3189 | 1710 | 855.0 | 49.44 | 24.7 | Mesenchymal stem cells as trophic mediators. | Arnold I Caplan, James E Dennis | J Cell Biochem | 2006 | 16619257 | No |
3190 | 1709 | 854.5 | 73.63 | 36.8 | Efficacy of the Theory of Planned Behaviour: a meta-analytic review. | C J Armitage, M Conner | Br J Soc Psychol | 2001 | 11795063 | Yes |
3191 | 3417 | 854.2 | 87.66 | 21.9 | Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. | E Schreiber, P Matthias, M M Müller, W Schaffner | Nucleic Acids Res | 1989 | 2771659 | Yes |
3192 | 854 | 854.0 | 33.81 | 33.8 | Cholesterol and the cell membrane. | P L Yeagle | Biochim Biophys Acta | 1985 | 3904832 | No |
3193 | 854 | 854.0 | 0.0 | 0.0 | Electrophoretic separation of plasma lipoproteins in agarose gel. | R P Noble | J Lipid Res | 1968 | 4176473 | Yes |
3194 | 854 | 854.0 | 35.04 | 35.0 | Post-hoc probing of significant moderational and mediational effects in studies of pediatric populations. | Grayson N Holmbeck | J Pediatr Psychol | 2002 | 11726683 | No |
3195 | 1708 | 854.0 | 0.0 | 0.0 | Virus interference. I. The interferon. | A ISAACS, J LINDENMANN | Proc R Soc Lond B Biol Sci | 1957 | 13465720 | Yes |
3196 | 854 | 854.0 | 20.74 | 20.7 | Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology. | Michael Forgac | Nat Rev Mol Cell Biol | 2007 | 17912264 | No |
3197 | 5975 | 853.6 | 209.42 | 29.9 | Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. | H P Adams, B H Bendixen, L J Kappelle, J Biller, B B Love, D L Gordon, E E Marsh | Stroke | 1993 | 7678184 | Yes |
3198 | 1707 | 853.5 | 0.0 | 0.0 | Establishment and characterization of a human histiocytic lymphoma cell line (U-937). | C Sundström, K Nilsson | Int J Cancer | 1976 | 178611 | Yes |
3199 | 1706 | 853.0 | 0.0 | 0.0 | Further improvements in the plaque technique for detecting single antibody-forming cells. | A J Cunningham, A Szenberg | Immunology | 1968 | 5653817 | Yes |
3200 | 853 | 853.0 | 30.69 | 30.7 | Muscarinic receptors--characterization, coupling and function. | M P Caulfield | Pharmacol Ther | 1993 | 7504306 | No |
3201 | 853 | 853.0 | 25.09 | 25.1 | Apoptosis in cancer therapy: crossing the threshold. | D E Fisher | Cell | 1994 | 8069905 | No |
3202 | 853 | 853.0 | 0.0 | 0.0 | On the psychophysical law. | S S STEVENS | Psychol Rev | 1957 | 13441853 | Yes |
3203 | 853 | 853.0 | 25.7 | 25.7 | Jasmonates: an update on biosynthesis, signal transduction and action in plant stress response, growth and development. | C Wasternack | Ann Bot | 2007 | 17513307 | No |
3204 | 853 | 853.0 | 0.0 | 0.0 | A Protection Motivation Theory of Fear Appeals and Attitude Change1. | Ronald W Rogers | J Psychol | 1975 | 28136248 | Yes |
3205 | 3411 | 852.8 | 98.1 | 24.5 | Universal sample preparation method for proteome analysis. | Jacek R Wiśniewski, Alexandre Zougman, Nagarjuna Nagaraj, Matthias Mann | Nat Methods | 2009 | 19377485 | Yes |
3206 | 1705 | 852.5 | 60.71 | 30.4 | Compilation and analysis of Escherichia coli promoter DNA sequences. | D K Hawley, W R McClure | Nucleic Acids Res | 1983 | 6344016 | No |
3207 | 3409 | 852.2 | 98.57 | 24.6 | Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. | J E Walker, M Saraste, M J Runswick, N J Gay | EMBO J | 1982 | 6329717 | Yes |
3208 | 852 | 852.0 | 0.0 | 0.0 | Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method. | K Satoh | Clin Chim Acta | 1978 | 719890 | Yes |
3209 | 852 | 852.0 | 32.07 | 32.1 | Signaling through phosphatidylcholine breakdown. | J H Exton | J Biol Chem | 1990 | 2104616 | No |
3210 | 852 | 852.0 | 23.88 | 23.9 | The orbitofrontal cortex and reward. | E T Rolls | Cereb Cortex | 2000 | 10731223 | No |
3211 | 1704 | 852.0 | 90.11 | 45.1 | Alginate: properties and biomedical applications. | Kuen Yong Lee, David J Mooney | Prog Polym Sci | 2012 | 22125349 | Yes |
3212 | 1703 | 851.5 | 44.08 | 22.0 | The Polycomb complex PRC2 and its mark in life. | Raphaël Margueron, Danny Reinberg | Nature | 2011 | 21248841 | No |
3213 | 851 | 851.0 | 0.0 | 0.0 | Radiochemical micro assays for the determination of choline acetyltransferase and acetylcholinesterase activities. | F Fonnum | Biochem J | 1969 | 4982085 | Yes |
3214 | 851 | 851.0 | 34.99 | 35.0 | Why we need observational studies to evaluate the effectiveness of health care. | N Black | BMJ | 1996 | 8634569 | Yes |
3215 | 851 | 851.0 | 40.0 | 40.0 | Gender variations in clinical pain experience. | A M Unruh | Pain | 1996 | 8826503 | No |
3216 | 851 | 851.0 | 22.99 | 23.0 | Tensegrity: the architectural basis of cellular mechanotransduction. | D E Ingber | Annu Rev Physiol | 1997 | 9074778 | No |
3217 | 851 | 851.0 | 24.21 | 24.2 | Nidovirales: a new order comprising Coronaviridae and Arteriviridae. | D Cavanagh | Arch Virol | 1997 | 9349308 | Yes |
3218 | 3404 | 851.0 | 67.76 | 16.9 | DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. | M Okano, D W Bell, D A Haber, E Li | Cell | 1999 | 10555141 | Yes |
3219 | 851 | 851.0 | 29.58 | 29.6 | The role of rumination in depressive disorders and mixed anxiety/depressive symptoms. | S Nolen-Hoeksema | J Abnorm Psychol | 2000 | 11016119 | Yes |
3220 | 1702 | 851.0 | 49.52 | 24.8 | Hydrogels for tissue engineering. | K Y Lee, D J Mooney | Chem Rev | 2001 | 11710233 | No |
3221 | 1701 | 850.5 | 40.02 | 20.0 | p53: puzzle and paradigm. | L J Ko, C Prives | Genes Dev | 1996 | 8654922 | No |
3222 | 850 | 850.0 | 17.83 | 17.8 | Progress in human tumour immunology and immunotherapy. | S A Rosenberg | Nature | 2001 | 11357146 | No |
3223 | 850 | 850.0 | 0.0 | 0.0 | The colorimetric determination of phosphorus. | E J King | Biochem J | 1932 | 16744823 | Yes |
3224 | 1700 | 850.0 | 37.37 | 18.7 | Phosphoinositides in cell regulation and membrane dynamics. | Gilbert Di Paolo, Pietro De Camilli | Nature | 2006 | 17035995 | No |
3225 | 1699 | 849.5 | 0.0 | 0.0 | Comparative aspects of the brain growth spurt. | J Dobbing, J Sands | Early Hum Dev | 1979 | 118862 | Yes |
3226 | 1699 | 849.5 | 0.0 | 0.0 | The hitch-hiking effect of a favourable gene. | J M Smith, J Haigh | Genet Res | 1974 | 4407212 | Yes |
3227 | 849 | 849.0 | 43.38 | 43.4 | Molecular aspects of ligand binding to serum albumin. | U Kragh-Hansen | Pharmacol Rev | 1981 | 7027277 | No |
3228 | 849 | 849.0 | 26.17 | 26.2 | The emotional dog and its rational tail: a social intuitionist approach to moral judgment. | J Haidt | Psychol Rev | 2001 | 11699120 | Yes |
3229 | 1698 | 849.0 | 34.1 | 17.1 | Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method. | R Daniel Gietz, Robin A Woods | Methods Enzymol | 2002 | 12073338 | Yes |
3230 | 849 | 849.0 | 28.16 | 28.2 | Neurophysiological and computational principles of cortical rhythms in cognition. | Xiao-Jing Wang | Physiol Rev | 2010 | 20664082 | No |
3231 | 1697 | 848.5 | 74.89 | 37.4 | Excitatory amino acid transmitters. | J C Watkins, R H Evans | Annu Rev Pharmacol Toxicol | 1981 | 6112965 | No |
3232 | 8485 | 848.5 | 219.27 | 21.9 | Scalable molecular dynamics with NAMD. | James C Phillips, Rosemary Braun, Wei Wang, James Gumbart, Emad Tajkhorshid, Elizabeth Villa, Christophe Chipot, Robert D Skeel, Laxmikant Kalé, Klaus Schulten | J Comput Chem | 2005 | 16222654 | Yes |
3233 | 2545 | 848.3 | 0.0 | 0.0 | Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs. | C A WINTER, E A RISLEY, G W NUSS | Proc Soc Exp Biol Med | 1962 | 14001233 | Yes |
3234 | 1696 | 848.0 | 61.97 | 31.0 | Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation. | J M Reul, E R de Kloet | Endocrinology | 1985 | 2998738 | Yes |
3235 | 1696 | 848.0 | 34.82 | 17.4 | Transcriptional regulation by the phosphorylation-dependent factor CREB. | B Mayr, M Montminy | Nat Rev Mol Cell Biol | 2001 | 11483993 | No |
3236 | 1696 | 848.0 | 37.32 | 18.7 | Autophagy in health and disease: a double-edged sword. | Takahiro Shintani, Daniel J Klionsky | Science | 2004 | 15528435 | No |
3237 | 848 | 848.0 | 49.3 | 49.3 | Mechanisms linking social ties and support to physical and mental health. | Peggy A Thoits | J Health Soc Behav | 2011 | 21673143 | No |
3238 | 1695 | 847.5 | 71.29 | 35.6 | Glutamate and the pathophysiology of hypoxic--ischemic brain damage. | S M Rothman, J W Olney | Ann Neurol | 1986 | 2421636 | No |
3239 | 1695 | 847.5 | 40.54 | 20.3 | Cell locomotion and focal adhesions are regulated by substrate flexibility. | R J Pelham, Y l Wang | Proc Natl Acad Sci U S A | 1997 | 9391082 | Yes |
3240 | 1695 | 847.5 | 48.16 | 24.1 | The amygdala: vigilance and emotion. | M Davis, P J Whalen | Mol Psychiatry | 2001 | 11244481 | No |
3241 | 1695 | 847.5 | 0.0 | 0.0 | The role of polyamines in the neutralization of bacteriophage deoxyribonucleic acid. | B N AMES, D T DUBIN | J Biol Chem | 1960 | 13793161 | Yes |
3242 | 1695 | 847.5 | 97.95 | 49.0 | 3D bioprinting of tissues and organs. | Sean V Murphy, Anthony Atala | Nat Biotechnol | 2014 | 25093879 | Yes |
3243 | 847 | 847.0 | 64.88 | 64.9 | The stabilizing system of the spine. Part I. Function, dysfunction, adaptation, and enhancement. | M M Panjabi | J Spinal Disord | 1992 | 1490034 | Yes |
3244 | 847 | 847.0 | 0.0 | 0.0 | Tests for emotionality in rats and mice: a review. | J Archer | Anim Behav | 1973 | 4578750 | No |
3245 | 847 | 847.0 | 0.0 | 0.0 | Human cardiovascular adjustments to exercise and thermal stress. | L B Rowell | Physiol Rev | 1974 | 4587247 | No |
3246 | 847 | 847.0 | 36.27 | 36.3 | Methods for dealing with reaction time outliers. | R Ratcliff | Psychol Bull | 1993 | 8272468 | Yes |
3247 | 847 | 847.0 | 28.21 | 28.2 | Rethinking schizophrenia. | Thomas R Insel | Nature | 2010 | 21068826 | No |
3248 | 1693 | 846.5 | 39.5 | 19.8 | A general empirical model of protein evolution derived from multiple protein families using a maximum-likelihood approach. | S Whelan, N Goldman | Mol Biol Evol | 2001 | 11319253 | Yes |
3249 | 846 | 846.0 | 24.38 | 24.4 | Lymphokine production by human T cells in disease states. | S Romagnani | Annu Rev Immunol | 1994 | 8011282 | No |
3250 | 846 | 846.0 | 28.21 | 28.2 | Growing group of extended-spectrum beta-lactamases: the CTX-M enzymes. | R Bonnet | Antimicrob Agents Chemother | 2004 | 14693512 | No |
3251 | 846 | 846.0 | 22.3 | 22.3 | The primate basal ganglia: parallel and integrative networks. | Suzanne N Haber | J Chem Neuroanat | 2003 | 14729134 | No |
3252 | 846 | 846.0 | 0.0 | 0.0 | Notes on continuous stochastic phenomena. | P A P MORAN | Biometrika | 1950 | 15420245 | Yes |
3253 | 846 | 846.0 | 26.0 | 26.0 | Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex. | Satoshi Ikemoto | Brain Res Rev | 2007 | 17574681 | No |
3254 | 846 | 846.0 | 28.33 | 28.3 | The global burden of hepatitis C. | Daniel Lavanchy | Liver Int | 2009 | 19207969 | No |
3255 | 3382 | 845.5 | 101.6 | 25.4 | A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. | I Vermes, C Haanen, H Steffens-Nakken, C Reutelingsperger | J Immunol Methods | 1995 | 7622868 | Yes |
3256 | 4225 | 845.0 | 175.93 | 35.2 | DNA primers for amplification of mitochondrial cytochrome c oxidase subunit I from diverse metazoan invertebrates. | O Folmer, M Black, W Hoeh, R Lutz, R Vrijenhoek | Mol Mar Biol Biotechnol | 1994 | 7881515 | Yes |
3257 | 845 | 845.0 | 17.15 | 17.1 | Computational systems biology. | Hiroaki Kitano | Nature | 2002 | 12432404 | No |
3258 | 845 | 845.0 | 18.53 | 18.5 | Validating survivin as a cancer therapeutic target. | Dario C Altieri | Nat Rev Cancer | 2003 | 12509766 | No |
3259 | 845 | 845.0 | 0.0 | 0.0 | PRELIMINARY TRIAL OF CARISOPRODOL IN MULTIPLE SCLEROSIS. | B ASHWORTH | Practitioner | 1964 | 14143329 | Yes |
3260 | 845 | 845.0 | 39.94 | 39.9 | U.S. Department of Agriculture and U.S. Department of Health and Human Services, Dietary Guidelines for Americans, 2010. 7th Edition, Washington, DC: U.S. Government Printing Office, January 2011. | Shelley McGuire | Adv Nutr | 2011 | 22332062 | Yes |
3261 | 2534 | 844.7 | 69.16 | 23.1 | Nitric oxide and macrophage function. | J MacMicking, Q W Xie, C Nathan | Annu Rev Immunol | 1997 | 9143691 | No |
3262 | 2533 | 844.3 | 62.58 | 20.9 | BCL-2 family members and the mitochondria in apoptosis. | A Gross, J M McDonnell, S J Korsmeyer | Genes Dev | 1999 | 10444588 | No |
3263 | 844 | 844.0 | 25.35 | 25.4 | The glycemic index: physiological mechanisms relating to obesity, diabetes, and cardiovascular disease. | David S Ludwig | JAMA | 2002 | 11988062 | No |
3264 | 844 | 844.0 | 18.7 | 18.7 | Molecular signatures of natural selection. | Rasmus Nielsen | Annu Rev Genet | 2005 | 16285858 | No |
3265 | 844 | 844.0 | 22.82 | 22.8 | Genomewide association studies and assessment of the risk of disease. | Teri A Manolio | N Engl J Med | 2010 | 20647212 | No |
3266 | 1687 | 843.5 | 52.69 | 26.3 | EasySpin, a comprehensive software package for spectral simulation and analysis in EPR. | Stefan Stoll, Arthur Schweiger | J Magn Reson | 2006 | 16188474 | Yes |
3267 | 8431 | 843.1 | 243.51 | 24.4 | Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. | M Dominici, K Le Blanc, I Mueller, I Slaper-Cortenbach, Fc Marini, Ds Krause, Rj Deans, A Keating, Dj Prockop, Em Horwitz | Cytotherapy | 2006 | 16923606 | Yes |
3268 | 843 | 843.0 | 0.0 | 0.0 | The moulding of senescence by natural selection. | W D Hamilton | J Theor Biol | 1966 | 6015424 | Yes |
3269 | 843 | 843.0 | 21.47 | 21.5 | Serine protease mechanism and specificity. | Lizbeth Hedstrom | Chem Rev | 2002 | 12475199 | No |
3270 | 843 | 843.0 | 22.77 | 22.8 | The emotional brain, fear, and the amygdala. | Joseph LeDoux | Cell Mol Neurobiol | 2003 | 14514027 | No |
3271 | 1686 | 843.0 | 38.49 | 19.2 | Protein aggregation and neurodegenerative disease. | Christopher A Ross, Michelle A Poirier | Nat Med | 2004 | 15272267 | No |
3272 | 2528 | 842.7 | 53.61 | 17.9 | Genetic instabilities in human cancers. | C Lengauer, K W Kinzler, B Vogelstein | Nature | 1998 | 9872311 | No |
3273 | 1684 | 842.0 | 75.13 | 37.6 | The Modified Mini-Mental State (3MS) examination. | E L Teng, H C Chui | J Clin Psychiatry | 1987 | 3611032 | Yes |
3274 | 1684 | 842.0 | 74.26 | 37.1 | Understanding face recognition. | V Bruce, A Young | Br J Psychol | 1986 | 3756376 | Yes |
3275 | 1684 | 842.0 | 41.57 | 20.8 | Principles of protein-protein interactions. | S Jones, J M Thornton | Proc Natl Acad Sci U S A | 1996 | 8552589 | No |
3276 | 1684 | 842.0 | 53.49 | 26.7 | Mechanisms of biofilm resistance to antimicrobial agents. | T F Mah, G A O'Toole | Trends Microbiol | 2001 | 11166241 | No |
3277 | 2526 | 842.0 | 52.07 | 17.4 | Exosomes: composition, biogenesis and function. | Clotilde Théry, Laurence Zitvogel, Sebastian Amigorena | Nat Rev Immunol | 2002 | 12154376 | No |
3278 | 842 | 842.0 | 15.88 | 15.9 | Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics. | Lynne E Maquat | Nat Rev Mol Cell Biol | 2004 | 15040442 | No |
3279 | 842 | 842.0 | 25.43 | 25.4 | Functionalized acenes and heteroacenes for organic electronics. | John E Anthony | Chem Rev | 2006 | 17165682 | Yes |
3280 | 842 | 842.0 | 26.81 | 26.8 | Principles of c-di-GMP signalling in bacteria. | Regine Hengge | Nat Rev Microbiol | 2009 | 19287449 | No |
3281 | 2526 | 842.0 | 78.13 | 26.0 | mTOR: from growth signal integration to cancer, diabetes and ageing. | Roberto Zoncu, Alejo Efeyan, David M Sabatini | Nat Rev Mol Cell Biol | 2011 | 21157483 | No |
3282 | 1683 | 841.5 | 44.81 | 22.4 | RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. | M B Shapiro, P Senapathy | Nucleic Acids Res | 1987 | 3658675 | Yes |
3283 | 841 | 841.0 | 19.86 | 19.9 | mRNA stability in mammalian cells. | J Ross | Microbiol Rev | 1995 | 7565413 | No |
3284 | 841 | 841.0 | 26.31 | 26.3 | The sphingomyelin cycle and the second messenger function of ceramide. | Y A Hannun | J Biol Chem | 1994 | 8106344 | No |
3285 | 841 | 841.0 | 47.49 | 47.5 | Toward terminological, conceptual, and statistical clarity in the study of mediators and moderators: examples from the child-clinical and pediatric psychology literatures. | G N Holmbeck | J Consult Clin Psychol | 1997 | 9256561 | Yes |
3286 | 841 | 841.0 | 15.63 | 15.6 | Molecular dissection of autophagy: two ubiquitin-like systems. | Y Ohsumi | Nat Rev Mol Cell Biol | 2001 | 11265251 | No |
3287 | 1682 | 841.0 | 46.06 | 23.0 | Toxoplasmosis. | J G Montoya, O Liesenfeld | Lancet | 2004 | 15194258 | No |
3288 | 1682 | 841.0 | 49.27 | 24.6 | Anemia of chronic disease. | Guenter Weiss, Lawrence T Goodnough | N Engl J Med | 2005 | 15758012 | No |
3289 | 841 | 841.0 | 17.01 | 17.0 | Chemistry. How are alkynes scrambled? | Uwe H F Bunz | Science | 2005 | 15821080 | No |
3290 | 841 | 841.0 | 29.62 | 29.6 | Stronger Brønsted acids. | Takahiko Akiyama | Chem Rev | 2007 | 17983247 | Yes |
3291 | 1681 | 840.5 | 59.05 | 29.5 | Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. | R A Ignotz, J Massagué | J Biol Chem | 1986 | 3456347 | Yes |
3292 | 840 | 840.0 | 38.3 | 38.3 | Epidemiological synergy. Interrelationships between human immunodeficiency virus infection and other sexually transmitted diseases. | J N Wasserheit | Sex Transm Dis | 1992 | 1595015 | No |
3293 | 1680 | 840.0 | 51.78 | 25.9 | The evolution of cooperation. | R Axelrod, W D Hamilton | Science | 1981 | 7466396 | Yes |
3294 | 840 | 840.0 | 20.53 | 20.5 | Dendritic cells: unique leukocyte populations which control the primary immune response. | D N Hart | Blood | 1997 | 9345009 | No |
3295 | 840 | 840.0 | 26.66 | 26.7 | What you see may not be what you get: a brief, nontechnical introduction to overfitting in regression-type models. | Michael A Babyak | Psychosom Med | 2004 | 15184705 | Yes |
3296 | 840 | 840.0 | 0.0 | 0.0 | Filter-paper partition chromatography of sugars: 1. General description and application to the qualitative analysis of sugars in apple juice, egg white and foetal blood of sheep. with a note by R. G. Westall. | S M Partridge | Biochem J | 1948 | 16748273 | Yes |
3297 | 2518 | 839.3 | 120.64 | 40.2 | Concurrent and predictive validity of a self-reported measure of medication adherence. | D E Morisky, L W Green, D M Levine | Med Care | 1986 | 3945130 | Yes |
3298 | 2518 | 839.3 | 69.76 | 23.3 | Astrocyte-endothelial interactions at the blood-brain barrier. | N Joan Abbott, Lars Rönnbäck, Elisabeth Hansson | Nat Rev Neurosci | 2006 | 16371949 | No |
3299 | 839 | 839.0 | 19.94 | 19.9 | Fluorescence spectroscopy of single biomolecules. | S Weiss | Science | 1999 | 10073925 | No |
3300 | 839 | 839.0 | 25.58 | 25.6 | Glutathione and its role in cellular functions. | H Sies | Free Radic Biol Med | 1999 | 10569624 | No |
3301 | 839 | 839.0 | 18.87 | 18.9 | The advantages and disadvantages of being polyploid. | Luca Comai | Nat Rev Genet | 2005 | 16304599 | No |
3302 | 2515 | 838.3 | 0.0 | 0.0 | High resolution two-dimensional electrophoresis of basic as well as acidic proteins. | P Z O'Farrell, H M Goodman, P H O'Farrell | Cell | 1977 | 23215 | Yes |
3303 | 1676 | 838.0 | 34.94 | 17.5 | Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. | J P Morgenstern, H Land | Nucleic Acids Res | 1990 | 2194165 | Yes |
3304 | 838 | 838.0 | 22.01 | 22.0 | The molecular biology of leukocyte chemoattractant receptors. | P M Murphy | Annu Rev Immunol | 1994 | 8011292 | No |
3305 | 838 | 838.0 | 32.68 | 32.7 | Properties of osteoconductive biomaterials: calcium phosphates. | Racquel Zapanta LeGeros | Clin Orthop Relat Res | 2002 | 11937868 | No |
3306 | 838 | 838.0 | 24.53 | 24.5 | Towards a neural basis of auditory sentence processing. | Angela D Friederici | Trends Cogn Sci | 2002 | 15866191 | Yes |
3307 | 838 | 838.0 | 30.19 | 30.2 | Models of speciation by sexual selection on polygenic traits. | R Lande | Proc Natl Acad Sci U S A | 1981 | 16593036 | Yes |
3308 | 838 | 838.0 | 0.0 | 0.0 | The free amino groups of insulin. | F Sanger | Biochem J | 1945 | 16747948 | Yes |
3309 | 838 | 838.0 | 78.54 | 78.5 | Making sense of implementation theories, models and frameworks. | Per Nilsen | Implement Sci | 2015 | 25895742 | Yes |
3310 | 2512 | 837.3 | 71.65 | 23.9 | Ghrelin induces adiposity in rodents. | M Tschöp, D L Smiley, M L Heiman | Nature | 2000 | 11057670 | Yes |
3311 | 2512 | 837.3 | 79.8 | 26.6 | Matrix metalloproteinases: regulators of the tumor microenvironment. | Kai Kessenbrock, Vicki Plaks, Zena Werb | Cell | 2010 | 20371345 | No |
3312 | 2512 | 837.3 | 139.13 | 46.4 | Scoping studies: advancing the methodology. | Danielle Levac, Heather Colquhoun, Kelly K O'Brien | Implement Sci | 2010 | 20854677 | Yes |
3313 | 837 | 837.0 | 29.96 | 30.0 | A human model of gastric carcinogenesis. | P Correa | Cancer Res | 1988 | 3288329 | No |
3314 | 837 | 837.0 | 17.54 | 17.5 | Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast. | L Guarente | Methods Enzymol | 1983 | 6310321 | Yes |
3315 | 837 | 837.0 | 17.31 | 17.3 | The lasso method for variable selection in the Cox model. | R Tibshirani | Stat Med | 1997 | 9044528 | Yes |
3316 | 837 | 837.0 | 21.33 | 21.3 | Angiogenesis. | Judah Folkman | Annu Rev Med | 2006 | 16409133 | No |
3317 | 1673 | 836.5 | 0.0 | 0.0 | Growth of a rat neuroblastoma cell line in serum-free supplemented medium. | J E Bottenstein, G H Sato | Proc Natl Acad Sci U S A | 1979 | 284369 | Yes |
3318 | 1673 | 836.5 | 86.16 | 43.1 | Tripartite model of anxiety and depression: psychometric evidence and taxonomic implications. | L A Clark, D Watson | J Abnorm Psychol | 1991 | 1918611 | No |
3319 | 1673 | 836.5 | 29.38 | 14.7 | Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. | Lee Zou, Stephen J Elledge | Science | 2003 | 12791985 | Yes |
3320 | 836 | 836.0 | 27.35 | 27.4 | Axonal growth-associated proteins. | J H Skene | Annu Rev Neurosci | 1989 | 2648946 | No |
3321 | 836 | 836.0 | 50.89 | 50.9 | Continuous improvement as an ideal in health care. | D M Berwick | N Engl J Med | 1989 | 2909878 | Yes |
3322 | 836 | 836.0 | 27.14 | 27.1 | Endothelial-leukocyte adhesion molecules. | M P Bevilacqua | Annu Rev Immunol | 1993 | 8476577 | No |
3323 | 836 | 836.0 | 16.86 | 16.9 | The Pezcoller lecture: cancer cell cycles revisited. | C J Sherr | Cancer Res | 2000 | 10919634 | No |
3324 | 1672 | 836.0 | 57.75 | 28.9 | Burden of major musculoskeletal conditions. | Anthony D Woolf, Bruce Pfleger | Bull World Health Organ | 2003 | 14710506 | No |
3325 | 836 | 836.0 | 21.25 | 21.2 | Oxygen, oxidative stress, hypoxia, and heart failure. | Frank J Giordano | J Clin Invest | 2005 | 15765131 | No |
3326 | 1672 | 836.0 | 40.63 | 20.3 | Angiogenesis as a therapeutic target. | Napoleone Ferrara, Robert S Kerbel | Nature | 2005 | 16355214 | No |
3327 | 836 | 836.0 | 0.0 | 0.0 | On the local reactions of the arterial wall to changes of internal pressure. | W M Bayliss | J Physiol | 1902 | 16992618 | Yes |
3328 | 1671 | 835.5 | 61.79 | 30.9 | Reactive oxygen species, cellular redox systems, and apoptosis. | Magdalena L Circu, Tak Yee Aw | Free Radic Biol Med | 2010 | 20045723 | No |
3329 | 835 | 835.0 | 0.0 | 0.0 | Letter: Grading of angina pectoris. | L Campeau | Circulation | 1976 | 947585 | Yes |
3330 | 1670 | 835.0 | 58.15 | 29.1 | Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. | C N Hales, D J Barker | Diabetologia | 1992 | 1644236 | No |
3331 | 835 | 835.0 | 48.13 | 48.1 | Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). | S Safe | Crit Rev Toxicol | 1990 | 2124811 | No |
3332 | 835 | 835.0 | 30.76 | 30.8 | Clinical practice. Preventing falls in elderly persons. | Mary E Tinetti | N Engl J Med | 2003 | 12510042 | No |
3333 | 835 | 835.0 | 0.0 | 0.0 | Voluntary strength and fatigue. | P A MERTON | J Physiol | 1954 | 13152698 | Yes |
3334 | 835 | 835.0 | 25.76 | 25.8 | The complex role of estrogens in inflammation. | Rainer H Straub | Endocr Rev | 2007 | 17640948 | No |
3335 | 3340 | 835.0 | 127.55 | 31.9 | Epidemiology and causes of preterm birth. | Robert L Goldenberg, Jennifer F Culhane, Jay D Iams, Roberto Romero | Lancet | 2008 | 18177778 | No |
3336 | 1670 | 835.0 | 60.01 | 30.0 | Type 2 diabetes as an inflammatory disease. | Marc Y Donath, Steven E Shoelson | Nat Rev Immunol | 2011 | 21233852 | No |
3337 | 3339 | 834.8 | 140.26 | 35.1 | Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. | S Pellow, P Chopin, S E File, M Briley | J Neurosci Methods | 1985 | 2864480 | Yes |
3338 | 1669 | 834.5 | 0.0 | 0.0 | Hearing lips and seeing voices. | H McGurk, J MacDonald | Nature | 1976 | 1012311 | Yes |
3339 | 834 | 834.0 | 0.0 | 0.0 | Structure of chromatin. | R D Kornberg | Annu Rev Biochem | 1977 | 332067 | No |
3340 | 834 | 834.0 | 40.39 | 40.4 | Omega-3 fatty acids in health and disease and in growth and development. | A P Simopoulos | Am J Clin Nutr | 1991 | 1908631 | No |
3341 | 1668 | 834.0 | 80.44 | 40.2 | Fingerprinting genomes using PCR with arbitrary primers. | J Welsh, M McClelland | Nucleic Acids Res | 1990 | 2259619 | Yes |
3342 | 834 | 834.0 | 30.78 | 30.8 | What is synergy? | M C Berenbaum | Pharmacol Rev | 1989 | 2692037 | No |
3343 | 1668 | 834.0 | 83.57 | 41.8 | Glutathione reductase. | I Carlberg, B Mannervik | Methods Enzymol | 1985 | 3003504 | Yes |
3344 | 834 | 834.0 | 27.09 | 27.1 | Receptors for epidermal growth factor and other polypeptide mitogens. | G Carpenter | Annu Rev Biochem | 1987 | 3039909 | No |
3345 | 834 | 834.0 | 23.14 | 23.1 | Variation in protection by BCG: implications of and for heterologous immunity. | P E Fine | Lancet | 1995 | 7475776 | No |
3346 | 834 | 834.0 | 32.03 | 32.0 | Perceptual load as a necessary condition for selective attention. | N Lavie | J Exp Psychol Hum Percept Perform | 1995 | 7790827 | Yes |
3347 | 834 | 834.0 | 27.61 | 27.6 | Apoptosis. | J J Cohen | Immunol Today | 1993 | 8466628 | No |
3348 | 834 | 834.0 | 27.45 | 27.4 | The stress response to trauma and surgery. | J P Desborough | Br J Anaesth | 2000 | 10927999 | No |
3349 | 5004 | 834.0 | 139.01 | 23.2 | Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. | D C Angus, W T Linde-Zwirble, J Lidicker, G Clermont, J Carcillo, M R Pinsky | Crit Care Med | 2001 | 11445675 | Yes |
3350 | 834 | 834.0 | 17.87 | 17.9 | The plasticity of aging: insights from long-lived mutants. | Cynthia Kenyon | Cell | 2005 | 15734678 | No |
3351 | 834 | 834.0 | 16.66 | 16.7 | Ubiquitin signalling in the NF-kappaB pathway. | Zhijian J Chen | Nat Cell Biol | 2005 | 16056267 | No |
3352 | 834 | 834.0 | 22.66 | 22.7 | A Population-Average, Landmark- and Surface-based (PALS) atlas of human cerebral cortex. | David C Van Essen | Neuroimage | 2005 | 16172003 | Yes |
3353 | 834 | 834.0 | 17.41 | 17.4 | Tetraspanin functions and associated microdomains. | Martin E Hemler | Nat Rev Mol Cell Biol | 2005 | 16314869 | No |
3354 | 3335 | 833.8 | 167.61 | 41.9 | Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010. | Katherine M Flegal, Margaret D Carroll, Brian K Kit, Cynthia L Ogden | JAMA | 2012 | 22253363 | Yes |
3355 | 2501 | 833.7 | 0.0 | 0.0 | Molecular weight estimation of polypeptide chains by electrophoresis in SDS-polyacrylamide gels. | A L Shapiro, E Viñuela, J V Maizel | Biochem Biophys Res Commun | 1967 | 4861258 | Yes |
3356 | 1667 | 833.5 | 0.0 | 0.0 | Immunization of dissociated spleen cell cultures from normal mice. | R I Mishell, R W Dutton | J Exp Med | 1967 | 6034749 | Yes |
3357 | 833 | 833.0 | 24.76 | 24.8 | Omega-3 fatty acids in inflammation and autoimmune diseases. | Artemis P Simopoulos | J Am Coll Nutr | 2002 | 12480795 | No |
3358 | 833 | 833.0 | 27.73 | 27.7 | Distracted and confused?: selective attention under load. | Nilli Lavie | Trends Cogn Sci | 2005 | 15668100 | No |
3359 | 1666 | 833.0 | 42.26 | 21.1 | Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. | William G Kaelin, Peter J Ratcliffe | Mol Cell | 2008 | 18498744 | No |
3360 | 833 | 833.0 | 22.79 | 22.8 | Solid-state nanopores. | Cees Dekker | Nat Nanotechnol | 2007 | 18654264 | No |
3361 | 2497 | 832.3 | 78.37 | 26.1 | The p53 tumour suppressor gene. | A J Levine, J Momand, C A Finlay | Nature | 1991 | 2046748 | No |
3362 | 4993 | 832.2 | 154.65 | 25.8 | Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. | D A Melton, P A Krieg, M R Rebagliati, T Maniatis, K Zinn, M R Green | Nucleic Acids Res | 1984 | 6091052 | Yes |
3363 | 4161 | 832.2 | 685.11 | 137.0 | MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms. | Sudhir Kumar, Glen Stecher, Michael Li, Christina Knyaz, Koichiro Tamura | Mol Biol Evol | 2018 | 29722887 | Yes |
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