No. | Citations | ECcit | RCR | ECRCR | Title | Authors | Journal | Year | PMID | Article(?) |
---|---|---|---|---|---|---|---|---|---|---|
1 | 224662 | 224662.0 | 4854.69 | 4854.7 | Cleavage of structural proteins during the assembly of the head of bacteriophage T4. | U K Laemmli | Nature | 1970 | 5432063 | Yes |
2 | 174035 | 174035.0 | 6866.6 | 6866.6 | A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. | M M Bradford | Anal Biochem | 1976 | 942051 | Yes |
3 | 286239 | 71559.8 | 0.0 | 0.0 | Protein measurement with the Folin phenol reagent. | O H Lowry, N J Rosebrough, A L Farr, R J Randall | J Biol Chem | 1951 | 14907713 | Yes |
4 | 125150 | 62575.0 | 3109.52 | 1554.8 | Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. | K J Livak, T D Schmittgen | Methods | 2001 | 11846609 | Yes |
5 | 45317 | 45317.0 | 1388.01 | 1388.0 | A short history of SHELX. | George M Sheldrick | Acta Crystallogr A | 2008 | 18156677 | Yes |
6 | 37029 | 37029.0 | 1195.07 | 1195.1 | Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. | T Mosmann | J Immunol Methods | 1983 | 6606682 | Yes |
7 | 64469 | 32234.5 | 1933.46 | 966.7 | Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. | P Chomczynski, N Sacchi | Anal Biochem | 1987 | 2440339 | Yes |
8 | 30235 | 30235.0 | 799.88 | 799.9 | Detection of specific sequences among DNA fragments separated by gel electrophoresis. | E M Southern | J Mol Biol | 1975 | 1195397 | Yes |
9 | 28019 | 28019.0 | 883.99 | 884.0 | The assessment and analysis of handedness: the Edinburgh inventory. | R C Oldfield | Neuropsychologia | 1971 | 5146491 | Yes |
10 | 27972 | 27972.0 | 614.56 | 614.6 | MicroRNAs: genomics, biogenesis, mechanism, and function. | David P Bartel | Cell | 2004 | 14744438 | No |
11 | 27481 | 27481.0 | 647.48 | 647.5 | MUSCLE: multiple sequence alignment with high accuracy and high throughput. | Robert C Edgar | Nucleic Acids Res | 2004 | 15034147 | Yes |
12 | 26186 | 26186.0 | 676.88 | 676.9 | A rating scale for depression. | M Hamilton | J Neurol Neurosurg Psychiatry | 1960 | 14399272 | Yes |
13 | 24981 | 24981.0 | 572.58 | 572.6 | A new mathematical model for relative quantification in real-time RT-PCR. | M W Pfaffl | Nucleic Acids Res | 2001 | 11328886 | Yes |
14 | 24586 | 24586.0 | 766.83 | 766.8 | Confidence Limits On Phylogenies: An Approach Using The Bootstrap. | Joseph Felsenstein | Evolution | 1985 | 28561359 | Yes |
15 | 66798 | 22266.0 | 2392.6 | 797.5 | "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. | M F Folstein, S E Folstein, P R McHugh | J Psychiatr Res | 1975 | 1202204 | Yes |
16 | 66046 | 22015.3 | 1641.99 | 547.3 | DNA sequencing with chain-terminating inhibitors. | F Sanger, S Nicklen, A R Coulson | Proc Natl Acad Sci U S A | 1977 | 271968 | Yes |
17 | 43521 | 21760.5 | 1343.99 | 672.0 | Hallmarks of cancer: the next generation. | Douglas Hanahan, Robert A Weinberg | Cell | 2011 | 21376230 | No |
18 | 40595 | 20297.5 | 1256.51 | 628.3 | The neighbor-joining method: a new method for reconstructing phylogenetic trees. | N Saitou, M Nei | Mol Biol Evol | 1987 | 3447015 | Yes |
19 | 20293 | 20293.0 | 204.71 | 204.7 | The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. | E S Reynolds | J Cell Biol | 1963 | 13986422 | Yes |
20 | 20077 | 20077.0 | 690.32 | 690.3 | Density-functional exchange-energy approximation with correct asymptotic behavior. | A D Becke | Phys Rev A Gen Phys | 1988 | 9900728 | Yes |
21 | 19633 | 19633.0 | 0.0 | 0.0 | Tissue sulfhydryl groups. | G L Ellman | Arch Biochem Biophys | 1959 | 13650640 | Yes |
22 | 18479 | 18479.0 | 514.62 | 514.6 | Projector augmented-wave method. | P E Blöchl | Phys Rev B Condens Matter | 1994 | 9976227 | Yes |
23 | 36830 | 18415.0 | 1526.4 | 763.2 | The measurement of observer agreement for categorical data. | J R Landis, G G Koch | Biometrics | 1977 | 843571 | Yes |
24 | 36813 | 18406.5 | 1735.28 | 867.6 | Statistical methods for assessing agreement between two methods of clinical measurement. | J M Bland, D G Altman | Lancet | 1986 | 2868172 | Yes |
25 | 53507 | 17835.7 | 1992.41 | 664.1 | Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. | H Towbin, T Staehelin, J Gordon | Proc Natl Acad Sci U S A | 1979 | 388439 | Yes |
26 | 17581 | 17581.0 | 738.5 | 738.5 | RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies. | Alexandros Stamatakis | Bioinformatics | 2014 | 24451623 | Yes |
27 | 17431 | 17431.0 | 641.47 | 641.5 | A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences. | M Kimura | J Mol Evol | 1980 | 7463489 | Yes |
28 | 17015 | 17015.0 | 426.53 | 426.5 | Atherosclerosis--an inflammatory disease. | R Ross | N Engl J Med | 1999 | 9887164 | No |
29 | 16817 | 16817.0 | 692.94 | 692.9 | A power primer. | J Cohen | Psychol Bull | 1992 | 19565683 | Yes |
30 | 16747 | 16747.0 | 282.98 | 283.0 | Disc Electrophoresis. Ii. Method And Application To Human Serum Proteins. | B J Davis | Ann N Y Acad Sci | 1964 | 14240539 | Yes |
31 | 49070 | 16356.7 | 1808.06 | 602.7 | Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. | Michael I Love, Wolfgang Huber, Simon Anders | Genome Biol | 2014 | 25516281 | Yes |
32 | 32619 | 16309.5 | 0.0 | 0.0 | A rapid method of total lipid extraction and purification. | E G Bligh, W J Dyer | Can J Biochem Physiol | 1959 | 13671378 | Yes |
33 | 32615 | 16307.5 | 1028.68 | 514.3 | Fast gapped-read alignment with Bowtie 2. | Ben Langmead, Steven L Salzberg | Nat Methods | 2012 | 22388286 | Yes |
34 | 16211 | 16211.0 | 435.63 | 435.6 | High resolution two-dimensional electrophoresis of proteins. | P H O'Farrell | J Biol Chem | 1975 | 236308 | Yes |
35 | 15922 | 15922.0 | 0.0 | 0.0 | A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. | K Burton | Biochem J | 1956 | 13293190 | Yes |
36 | 31505 | 15752.5 | 793.94 | 397.0 | Fast and accurate short read alignment with Burrows-Wheeler transform. | Heng Li, Richard Durbin | Bioinformatics | 2009 | 19451168 | Yes |
37 | 46984 | 15661.3 | 1391.25 | 463.8 | Generalized Gradient Approximation Made Simple. | J P Perdew, K Burke, M Ernzerhof | Phys Rev Lett | 1996 | 10062328 | Yes |
38 | 15483 | 15483.0 | 386.5 | 386.5 | MicroRNAs: target recognition and regulatory functions. | David P Bartel | Cell | 2009 | 19167326 | No |
39 | 30690 | 15345.0 | 1226.91 | 613.5 | The hospital anxiety and depression scale. | A S Zigmond, R P Snaith | Acta Psychiatr Scand | 1983 | 6880820 | Yes |
40 | 45499 | 15166.3 | 1298.61 | 432.9 | CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. | J D Thompson, D G Higgins, T J Gibson | Nucleic Acids Res | 1994 | 7984417 | Yes |
41 | 30046 | 15023.0 | 1125.84 | 562.9 | Meta-analysis in clinical trials. | R DerSimonian, N Laird | Control Clin Trials | 1986 | 3802833 | Yes |
42 | 14546 | 14546.0 | 567.44 | 567.4 | Catalase in vitro. | H Aebi | Methods Enzymol | 1984 | 6727660 | Yes |
43 | 42207 | 14069.0 | 0.0 | 0.0 | A simple method for the isolation and purification of total lipides from animal tissues. | J Folch, M Lees, G H Sloane Stanley | J Biol Chem | 1957 | 13428781 | Yes |
44 | 13215 | 13215.0 | 665.06 | 665.1 | Crystal structure refinement with SHELXL. | George M Sheldrick | Acta Crystallogr C Struct Chem | 2015 | 25567568 | Yes |
45 | 64326 | 12865.2 | 1847.67 | 369.5 | Basic local alignment search tool. | S F Altschul, W Gish, W Miller, E W Myers, D J Lipman | J Mol Biol | 1990 | 2231712 | Yes |
46 | 25543 | 12771.5 | 524.92 | 262.5 | Coot: model-building tools for molecular graphics. | Paul Emsley, Kevin Cowtan | Acta Crystallogr D Biol Crystallogr | 2004 | 15572765 | Yes |
47 | 25366 | 12683.0 | 695.12 | 347.6 | Efficient iterative schemes for ab initio total-energy calculations using a plane-wave basis set. | G Kresse, J Furthmüller | Phys Rev B Condens Matter | 1996 | 9984901 | Yes |
48 | 25277 | 12638.5 | 1035.31 | 517.7 | The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. | J E Ware, C D Sherbourne | Med Care | 1992 | 1593914 | Yes |
49 | 12633 | 12633.0 | 0.0 | 0.0 | Phosphorus assay in column chromatography. | G R Bartlett | J Biol Chem | 1959 | 13641241 | Yes |
50 | 12632 | 12632.0 | 320.73 | 320.7 | Xds. | Wolfgang Kabsch | Acta Crystallogr D Biol Crystallogr | 2010 | 20124692 | Yes |
51 | 12540 | 12540.0 | 399.13 | 399.1 | Search and clustering orders of magnitude faster than BLAST. | Robert C Edgar | Bioinformatics | 2010 | 20709691 | Yes |
52 | 12326 | 12326.0 | 566.6 | 566.6 | Self-efficacy: toward a unifying theory of behavioral change. | A Bandura | Psychol Rev | 1977 | 847061 | Yes |
53 | 12264 | 12264.0 | 370.43 | 370.4 | The Psychophysics Toolbox. | D H Brainard | Spat Vis | 1997 | 9176952 | Yes |
54 | 24314 | 12157.0 | 656.38 | 328.2 | Quantifying heterogeneity in a meta-analysis. | Julian P T Higgins, Simon G Thompson | Stat Med | 2002 | 12111919 | Yes |
55 | 12146 | 12146.0 | 139.04 | 139.0 | The genetics of Caenorhabditis elegans. | S Brenner | Genetics | 1974 | 4366476 | Yes |
56 | 36092 | 12030.7 | 1273.74 | 424.6 | Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density. | C Lee, W Yang, R G Parr | Phys Rev B Condens Matter | 1988 | 9944570 | Yes |
57 | 23927 | 11963.5 | 521.22 | 260.6 | Processing of X-ray diffraction data collected in oscillation mode. | Z Otwinowski, W Minor | Methods Enzymol | 1997 | 27754618 | Yes |
58 | 35658 | 11886.0 | 1378.89 | 459.6 | Trimmomatic: a flexible trimmer for Illumina sequence data. | Anthony M Bolger, Marc Lohse, Bjoern Usadel | Bioinformatics | 2014 | 24695404 | Yes |
59 | 11786 | 11786.0 | 388.78 | 388.8 | Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). | J F Kurtzke | Neurology | 1983 | 6685237 | Yes |
60 | 11583 | 11583.0 | 460.84 | 460.8 | Investigation of the freely available easy-to-use software 'EZR' for medical statistics. | Y Kanda | Bone Marrow Transplant | 2013 | 23208313 | Yes |
61 | 11427 | 11427.0 | 395.87 | 395.9 | Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. | Andreas Stang | Eur J Epidemiol | 2010 | 20652370 | Yes |
62 | 22581 | 11290.5 | 858.89 | 429.4 | MAFFT multiple sequence alignment software version 7: improvements in performance and usability. | Kazutaka Katoh, Daron M Standley | Mol Biol Evol | 2013 | 23329690 | Yes |
63 | 11152 | 11152.0 | 424.87 | 424.9 | A new method for measuring daytime sleepiness: the Epworth sleepiness scale. | M W Johns | Sleep | 1991 | 1798888 | Yes |
64 | 21686 | 10843.0 | 467.2 | 233.6 | KEGG: kyoto encyclopedia of genes and genomes. | M Kanehisa, S Goto | Nucleic Acids Res | 2000 | 10592173 | Yes |
65 | 21560 | 10780.0 | 558.45 | 279.2 | A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. | A P Feinberg, B Vogelstein | Anal Biochem | 1983 | 6312838 | Yes |
66 | 32248 | 10749.3 | 1078.67 | 359.6 | NIH Image to ImageJ: 25 years of image analysis. | Caroline A Schneider, Wayne S Rasband, Kevin W Eliceiri | Nat Methods | 2012 | 22930834 | No |
67 | 32043 | 10681.0 | 832.91 | 277.6 | VMD: visual molecular dynamics. | W Humphrey, A Dalke, K Schulten | J Mol Graph | 1996 | 8744570 | Yes |
68 | 21132 | 10566.0 | 901.51 | 450.8 | The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. | R M Baron, D A Kenny | J Pers Soc Psychol | 1986 | 3806354 | Yes |
69 | 10527 | 10527.0 | 362.98 | 363.0 | Structure validation in chemical crystallography. | Anthony L Spek | Acta Crystallogr D Biol Crystallogr | 2009 | 19171970 | Yes |
70 | 21033 | 10516.5 | 460.8 | 230.4 | [20] Processing of X-ray diffraction data collected in oscillation mode. | Zbyszek Otwinowski, Wladek Minor | Methods Enzymol | 1997 | 27799103 | Yes |
71 | 41975 | 10493.8 | 1197.4 | 299.4 | Measuring inconsistency in meta-analyses. | Julian P T Higgins, Simon G Thompson, Jonathan J Deeks, Douglas G Altman | BMJ | 2003 | 12958120 | No |
72 | 10319 | 10319.0 | 462.62 | 462.6 | Prokka: rapid prokaryotic genome annotation. | Torsten Seemann | Bioinformatics | 2014 | 24642063 | Yes |
73 | 10294 | 10294.0 | 201.71 | 201.7 | Improvements in epoxy resin embedding methods. | J H Luft | J Biophys Biochem Cytol | 1961 | 13764136 | Yes |
74 | 41027 | 10256.8 | 1576.87 | 394.2 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | PLoS Med | 2009 | 19621072 | No |
75 | 10054 | 10054.0 | 0.0 | 0.0 | On the origin of cancer cells. | O Warburg | Science | 1956 | 13298683 | Yes |
76 | 19800 | 9900.0 | 371.91 | 186.0 | The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. | K Weber, M Osborn | J Biol Chem | 1969 | 5806584 | Yes |
77 | 9821 | 9821.0 | 420.15 | 420.1 | Psychophysical bases of perceived exertion. | G A Borg | Med Sci Sports Exerc | 1982 | 7154893 | Yes |
78 | 9699 | 9699.0 | 273.69 | 273.7 | Evolutionary trees from DNA sequences: a maximum likelihood approach. | J Felsenstein | J Mol Evol | 1981 | 7288891 | Yes |
79 | 9656 | 9656.0 | 199.56 | 199.6 | Mfold web server for nucleic acid folding and hybridization prediction. | Michael Zuker | Nucleic Acids Res | 2003 | 12824337 | Yes |
80 | 9604 | 9604.0 | 253.54 | 253.5 | Semiempirical GGA-type density functional constructed with a long-range dispersion correction. | Stefan Grimme | J Comput Chem | 2006 | 16955487 | Yes |
81 | 19039 | 9519.5 | 491.05 | 245.5 | A simple method for displaying the hydropathic character of a protein. | J Kyte, R F Doolittle | J Mol Biol | 1982 | 7108955 | Yes |
82 | 9498 | 9498.0 | 275.08 | 275.1 | The blockade of immune checkpoints in cancer immunotherapy. | Drew M Pardoll | Nat Rev Cancer | 2012 | 22437870 | No |
83 | 9491 | 9491.0 | 317.75 | 317.8 | Banting lecture 1988. Role of insulin resistance in human disease. | G M Reaven | Diabetes | 1988 | 3056758 | No |
84 | 9396 | 9396.0 | 249.0 | 249.0 | Studies on transformation of Escherichia coli with plasmids. | D Hanahan | J Mol Biol | 1983 | 6345791 | Yes |
85 | 9385 | 9385.0 | 270.1 | 270.1 | Vitamin D deficiency. | Michael F Holick | N Engl J Med | 2007 | 17634462 | No |
86 | 37371 | 9342.8 | 1370.44 | 342.6 | A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. | M E Charlson, P Pompei, K L Ales, C R MacKenzie | J Chronic Dis | 1987 | 3558716 | Yes |
87 | 9332 | 9332.0 | 241.02 | 241.0 | RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. | Alexandros Stamatakis | Bioinformatics | 2006 | 16928733 | Yes |
88 | 9255 | 9255.0 | 262.88 | 262.9 | Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. | P S Thomas | Proc Natl Acad Sci U S A | 1980 | 6159641 | Yes |
89 | 18359 | 9179.5 | 383.04 | 191.5 | The hallmarks of cancer. | D Hanahan, R A Weinberg | Cell | 2000 | 10647931 | No |
90 | 9173 | 9173.0 | 258.86 | 258.9 | The pathogenesis of atherosclerosis: a perspective for the 1990s. | R Ross | Nature | 1993 | 8479518 | No |
91 | 9041 | 9041.0 | 232.92 | 232.9 | Integrins: versatility, modulation, and signaling in cell adhesion. | R O Hynes | Cell | 1992 | 1555235 | No |
92 | 9018 | 9018.0 | 217.24 | 217.2 | PAML 4: phylogenetic analysis by maximum likelihood. | Ziheng Yang | Mol Biol Evol | 2007 | 17483113 | Yes |
93 | 35903 | 8975.8 | 1160.85 | 290.2 | Bias in meta-analysis detected by a simple, graphical test. | M Egger, G Davey Smith, M Schneider, C Minder | BMJ | 1997 | 9310563 | Yes |
94 | 17910 | 8955.0 | 469.56 | 234.8 | Analyzing real-time PCR data by the comparative C(T) method. | Thomas D Schmittgen, Kenneth J Livak | Nat Protoc | 2008 | 18546601 | Yes |
95 | 26829 | 8943.0 | 682.7 | 227.6 | Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. | Da Wei Huang, Brad T Sherman, Richard A Lempicki | Nat Protoc | 2009 | 19131956 | Yes |
96 | 8846 | 8846.0 | 0.0 | 0.0 | Copper Enzymes In Isolated Chloroplasts. Polyphenoloxidase In Beta Vulgaris. | D I Arnon | Plant Physiol | 1949 | 16654194 | Yes |
97 | 52934 | 8822.3 | 3379.46 | 563.2 | Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. | Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal | CA Cancer J Clin | 2018 | 30207593 | Yes |
98 | 8791 | 8791.0 | 176.85 | 176.8 | Linear models and empirical bayes methods for assessing differential expression in microarray experiments. | Gordon K Smyth | Stat Appl Genet Mol Biol | 2004 | 16646809 | Yes |
99 | 8760 | 8760.0 | 227.56 | 227.6 | Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. | M C Hochberg | Arthritis Rheum | 1997 | 9324032 | Yes |
100 | 17471 | 8735.5 | 381.75 | 190.9 | Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. | Kazutoshi Takahashi, Shinya Yamanaka | Cell | 2006 | 16904174 | Yes |
101 | 25975 | 8658.3 | 687.59 | 229.2 | edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. | Mark D Robinson, Davis J McCarthy, Gordon K Smyth | Bioinformatics | 2010 | 19910308 | Yes |
102 | 8566 | 8566.0 | 181.03 | 181.0 | The functions of animal microRNAs. | Victor Ambros | Nature | 2004 | 15372042 | No |
103 | 8545 | 8545.0 | 222.97 | 223.0 | Canonical dynamics: Equilibrium phase-space distributions. | WG Hoover | Phys Rev A Gen Phys | 1985 | 9895674 | Yes |
104 | 8499 | 8499.0 | 357.86 | 357.9 | UPARSE: highly accurate OTU sequences from microbial amplicon reads. | Robert C Edgar | Nat Methods | 2013 | 23955772 | Yes |
105 | 8370 | 8370.0 | 218.32 | 218.3 | Apoptosis: a review of programmed cell death. | Susan Elmore | Toxicol Pathol | 2007 | 17562483 | No |
106 | 8350 | 8350.0 | 246.47 | 246.5 | AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. | R W Cox | Comput Biomed Res | 1996 | 8812068 | Yes |
107 | 8330 | 8330.0 | 0.0 | 0.0 | The assessment of anxiety states by rating. | M Hamilton | Br J Med Psychol | 1959 | 13638508 | Yes |
108 | 24980 | 8326.7 | 1368.87 | 456.3 | MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets. | Sudhir Kumar, Glen Stecher, Koichiro Tamura | Mol Biol Evol | 2016 | 27004904 | Yes |
109 | 8313 | 8313.0 | 407.39 | 407.4 | SHELXT - integrated space-group and crystal-structure determination. | George M Sheldrick | Acta Crystallogr A Found Adv | 2015 | 25537383 | Yes |
110 | 24928 | 8309.3 | 735.03 | 245.0 | The PHQ-9: validity of a brief depression severity measure. | K Kroenke, R L Spitzer, J B Williams | J Gen Intern Med | 2001 | 11556941 | Yes |
111 | 8100 | 8100.0 | 179.87 | 179.9 | Solvent content of protein crystals. | B W Matthews | J Mol Biol | 1968 | 5700707 | Yes |
112 | 7985 | 7985.0 | 370.31 | 370.3 | Comparative fit indexes in structural models. | P M Bentler | Psychol Bull | 1990 | 2320703 | Yes |
113 | 55862 | 7980.3 | 7378.71 | 1054.1 | Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. | Hyuna Sung, Jacques Ferlay, Rebecca L Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, Freddie Bray | CA Cancer J Clin | 2021 | 33538338 | Yes |
114 | 15907 | 7953.5 | 378.16 | 189.1 | BEDTools: a flexible suite of utilities for comparing genomic features. | Aaron R Quinlan, Ira M Hall | Bioinformatics | 2010 | 20110278 | Yes |
115 | 7891 | 7891.0 | 213.55 | 213.6 | Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. | F Tajima | Genetics | 1989 | 2513255 | Yes |
116 | 7869 | 7869.0 | 217.54 | 217.5 | "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. | W N Burnette | Anal Biochem | 1981 | 6266278 | Yes |
117 | 15730 | 7865.0 | 353.62 | 176.8 | Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana. | S J Clough, A F Bent | Plant J | 1998 | 10069079 | Yes |
118 | 15691 | 7845.5 | 382.18 | 191.1 | MrBayes 3: Bayesian phylogenetic inference under mixed models. | Fredrik Ronquist, John P Huelsenbeck | Bioinformatics | 2003 | 12912839 | Yes |
119 | 7800 | 7800.0 | 224.62 | 224.6 | A simplification of the protein assay method of Lowry et al. which is more generally applicable. | G L Peterson | Anal Biochem | 1977 | 603028 | Yes |
120 | 7786 | 7786.0 | 216.3 | 216.3 | The role of protein kinase C in cell surface signal transduction and tumour promotion. | Y Nishizuka | Nature | 1984 | 6232463 | No |
121 | 7747 | 7747.0 | 151.9 | 151.9 | Tumor angiogenesis: therapeutic implications. | J Folkman | N Engl J Med | 1971 | 4938153 | No |
122 | 15380 | 7690.0 | 515.99 | 258.0 | Three approaches to qualitative content analysis. | Hsiu-Fang Hsieh, Sarah E Shannon | Qual Health Res | 2005 | 16204405 | Yes |
123 | 7658 | 7658.0 | 188.68 | 188.7 | Fast robust automated brain extraction. | Stephen M Smith | Hum Brain Mapp | 2002 | 12391568 | No |
124 | 7642 | 7642.0 | 209.67 | 209.7 | Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. | A Böyum | Scand J Clin Lab Invest Suppl | 1968 | 4179068 | Yes |
125 | 7640 | 7640.0 | 219.43 | 219.4 | Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. | J R Vane | Nat New Biol | 1971 | 5284360 | Yes |
126 | 22913 | 7637.7 | 691.21 | 230.4 | Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. | Daniel Dindo, Nicolas Demartines, Pierre-Alain Clavien | Ann Surg | 2004 | 15273542 | Yes |
127 | 7621 | 7621.0 | 162.29 | 162.3 | Chromatin modifications and their function. | Tony Kouzarides | Cell | 2007 | 17320507 | No |
128 | 22695 | 7565.0 | 887.22 | 295.7 | Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. | W T Friedewald, R I Levy, D S Fredrickson | Clin Chem | 1972 | 4337382 | Yes |
129 | 7419 | 7419.0 | 234.35 | 234.3 | The Clinical Dementia Rating (CDR): current version and scoring rules. | J C Morris | Neurology | 1993 | 8232972 | Yes |
130 | 51782 | 7397.4 | 1332.79 | 190.4 | Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. | S F Altschul, T L Madden, A A Schäffer, J Zhang, Z Zhang, W Miller, D J Lipman | Nucleic Acids Res | 1997 | 9254694 | No |
131 | 14767 | 7383.5 | 451.79 | 225.9 | AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. | Oleg Trott, Arthur J Olson | J Comput Chem | 2010 | 19499576 | Yes |
132 | 7363 | 7363.0 | 124.06 | 124.1 | A low-viscosity epoxy resin embedding medium for electron microscopy. | A R Spurr | J Ultrastruct Res | 1969 | 4887011 | Yes |
133 | 29395 | 7348.8 | 961.55 | 240.4 | G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. | Franz Faul, Edgar Erdfelder, Albert-Georg Lang, Axel Buchner | Behav Res Methods | 2007 | 17695343 | Yes |
134 | 7325 | 7325.0 | 242.23 | 242.2 | Density-functional approximation for the correlation energy of the inhomogeneous electron gas. | J P Perdew | Phys Rev B Condens Matter | 1986 | 9938299 | Yes |
135 | 7324 | 7324.0 | 220.63 | 220.6 | The VideoToolbox software for visual psychophysics: transforming numbers into movies. | D G Pelli | Spat Vis | 1997 | 9176953 | Yes |
136 | 7093 | 7093.0 | 249.16 | 249.2 | The Strengths and Difficulties Questionnaire: a research note. | R Goodman | J Child Psychol Psychiatry | 1997 | 9255702 | Yes |
137 | 14182 | 7091.0 | 334.7 | 167.3 | WGCNA: an R package for weighted correlation network analysis. | Peter Langfelder, Steve Horvath | BMC Bioinformatics | 2008 | 19114008 | Yes |
138 | 7060 | 7060.0 | 192.29 | 192.3 | TreeView: an application to display phylogenetic trees on personal computers. | R D Page | Comput Appl Biosci | 1996 | 8902363 | Yes |
139 | 13770 | 6885.0 | 341.96 | 171.0 | Continuous cultures of fused cells secreting antibody of predefined specificity. | G Köhler, C Milstein | Nature | 1975 | 1172191 | Yes |
140 | 6842 | 6842.0 | 183.29 | 183.3 | The steroid and thyroid hormone receptor superfamily. | R M Evans | Science | 1988 | 3283939 | No |
141 | 6764 | 6764.0 | 177.91 | 177.9 | A modified poisson regression approach to prospective studies with binary data. | Guangyong Zou | Am J Epidemiol | 2004 | 15033648 | Yes |
142 | 13435 | 6717.5 | 728.48 | 364.2 | Intraclass correlations: uses in assessing rater reliability. | P E Shrout, J L Fleiss | Psychol Bull | 1979 | 18839484 | No |
143 | 6706 | 6706.0 | 0.0 | 0.0 | The thiobarbituric acid assay of sialic acids. | L Warren | J Biol Chem | 1959 | 13672998 | Yes |
144 | 6616 | 6616.0 | 0.0 | 0.0 | Index for rating diagnostic tests. | W J Youden | Cancer | 1950 | 15405679 | Yes |
145 | 13202 | 6601.0 | 0.0 | 0.0 | Statistical aspects of the analysis of data from retrospective studies of disease. | N Mantel, W Haenszel | J Natl Cancer Inst | 1959 | 13655060 | Yes |
146 | 13178 | 6589.0 | 308.74 | 154.4 | Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. | Y Cheng, W H Prusoff | Biochem Pharmacol | 1973 | 4202581 | Yes |
147 | 6567 | 6567.0 | 214.34 | 214.3 | Ethical guidelines for investigations of experimental pain in conscious animals. | Manfred Zimmermann | Pain | 1983 | 6877845 | No |
148 | 19693 | 6564.3 | 552.52 | 184.2 | A new generation of Ca2+ indicators with greatly improved fluorescence properties. | G Grynkiewicz, M Poenie, R Y Tsien | J Biol Chem | 1985 | 3838314 | Yes |
149 | 13105 | 6552.5 | 363.04 | 181.5 | EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis. | Arnaud Delorme, Scott Makeig | J Neurosci Methods | 2004 | 15102499 | Yes |
150 | 6552 | 6552.0 | 172.23 | 172.2 | Adhesion receptors of the immune system. | T A Springer | Nature | 1990 | 1974032 | No |
151 | 6545 | 6545.0 | 129.38 | 129.4 | Integrins: bidirectional, allosteric signaling machines. | Richard O Hynes | Cell | 2002 | 12297042 | No |
152 | 6521 | 6521.0 | 169.07 | 169.1 | Angiogenesis in cancer, vascular, rheumatoid and other disease. | J Folkman | Nat Med | 1995 | 7584949 | No |
153 | 12944 | 6472.0 | 358.6 | 179.3 | RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. | Bo Li, Colin N Dewey | BMC Bioinformatics | 2011 | 21816040 | Yes |
154 | 6423 | 6423.0 | 113.15 | 113.2 | A Self-Rating Depression Scale. | W W Zung | Arch Gen Psychiatry | 1965 | 14221692 | Yes |
155 | 12832 | 6416.0 | 859.72 | 429.9 | A Guideline of Selecting and Reporting Intraclass Correlation Coefficients for Reliability Research. | Terry K Koo, Mae Y Li | J Chiropr Med | 2016 | 27330520 | Yes |
156 | 6410 | 6410.0 | 219.09 | 219.1 | An Introduction to Propensity Score Methods for Reducing the Effects of Confounding in Observational Studies. | Peter C Austin | Multivariate Behav Res | 2011 | 21818162 | Yes |
157 | 6409 | 6409.0 | 150.64 | 150.6 | Inflammation, atherosclerosis, and coronary artery disease. | Göran K Hansson | N Engl J Med | 2005 | 15843671 | No |
158 | 6405 | 6405.0 | 129.24 | 129.2 | Rapid and efficient site-specific mutagenesis without phenotypic selection. | T A Kunkel | Proc Natl Acad Sci U S A | 1985 | 3881765 | Yes |
159 | 6367 | 6367.0 | 282.83 | 282.8 | Interrater reliability: the kappa statistic. | Mary L McHugh | Biochem Med (Zagreb) | 2012 | 23092060 | Yes |
160 | 19063 | 6354.3 | 668.59 | 222.9 | Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. | Allison Tong, Peter Sainsbury, Jonathan Craig | Int J Qual Health Care | 2007 | 17872937 | Yes |
161 | 6352 | 6352.0 | 135.04 | 135.0 | p53, the cellular gatekeeper for growth and division. | A J Levine | Cell | 1997 | 9039259 | No |
162 | 12657 | 6328.5 | 432.44 | 216.2 | The meaning and use of the area under a receiver operating characteristic (ROC) curve. | J A Hanley, B J McNeil | Radiology | 1982 | 7063747 | Yes |
163 | 12636 | 6318.0 | 505.05 | 252.5 | Prediction of creatinine clearance from serum creatinine. | D W Cockcroft, M H Gault | Nephron | 1976 | 1244564 | Yes |
164 | 6307 | 6307.0 | 296.31 | 296.3 | Minimap2: pairwise alignment for nucleotide sequences. | Heng Li | Bioinformatics | 2018 | 29750242 | Yes |
165 | 6267 | 6267.0 | 143.96 | 144.0 | Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis. | J Castresana | Mol Biol Evol | 2000 | 10742046 | Yes |
166 | 6255 | 6255.0 | 136.09 | 136.1 | Inflammation in atherosclerosis. | Peter Libby | Nature | 2002 | 12490960 | No |
167 | 6224 | 6224.0 | 146.52 | 146.5 | Biochemistry and molecular cell biology of diabetic complications. | M Brownlee | Nature | 2001 | 11742414 | Yes |
168 | 6189 | 6189.0 | 115.37 | 115.4 | BLAT--the BLAST-like alignment tool. | W James Kent | Genome Res | 2002 | 11932250 | Yes |
169 | 6170 | 6170.0 | 143.97 | 144.0 | Free radicals in the physiological control of cell function. | Wulf Dröge | Physiol Rev | 2002 | 11773609 | No |
170 | 18400 | 6133.3 | 915.14 | 305.0 | Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. | H Ohkawa, N Ohishi, K Yagi | Anal Biochem | 1979 | 36810 | Yes |
171 | 12252 | 6126.0 | 435.5 | 217.8 | A rapid alkaline extraction procedure for screening recombinant plasmid DNA. | H C Birnboim, J Doly | Nucleic Acids Res | 1979 | 388356 | Yes |
172 | 6093 | 6093.0 | 148.94 | 148.9 | Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. | T A Springer | Cell | 1994 | 7507411 | No |
173 | 6079 | 6079.0 | 146.36 | 146.4 | Inflammation and metabolic disorders. | Gökhan S Hotamisligil | Nature | 2006 | 17167474 | No |
174 | 6039 | 6039.0 | 152.44 | 152.4 | G proteins: transducers of receptor-generated signals. | A G Gilman | Annu Rev Biochem | 1987 | 3113327 | No |
175 | 6024 | 6024.0 | 151.66 | 151.7 | Inositol trisphosphate and calcium signalling. | M J Berridge | Nature | 1993 | 8381210 | No |
176 | 23967 | 5991.8 | 774.06 | 193.5 | Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. | J M Chirgwin, A E Przybyla, R J MacDonald, W J Rutter | Biochemistry | 1979 | 518835 | Yes |
177 | 11983 | 5991.5 | 291.61 | 145.8 | MRBAYES: Bayesian inference of phylogenetic trees. | J P Huelsenbeck, F Ronquist | Bioinformatics | 2001 | 11524383 | Yes |
178 | 5942 | 5942.0 | 136.95 | 136.9 | Antimicrobial peptides of multicellular organisms. | Michael Zasloff | Nature | 2002 | 11807545 | Yes |
179 | 11755 | 5877.5 | 255.51 | 127.8 | One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. | K A Datsenko, B L Wanner | Proc Natl Acad Sci U S A | 2000 | 10829079 | Yes |
180 | 11743 | 5871.5 | 320.11 | 160.1 | Neuropathological stageing of Alzheimer-related changes. | H Braak, E Braak | Acta Neuropathol | 1991 | 1759558 | No |
181 | 11720 | 5860.0 | 269.99 | 135.0 | Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features. | W Kabsch, C Sander | Biopolymers | 1983 | 6667333 | Yes |
182 | 11706 | 5853.0 | 308.2 | 154.1 | Balanced basis sets of split valence, triple zeta valence and quadruple zeta valence quality for H to Rn: Design and assessment of accuracy. | Florian Weigend, Reinhart Ahlrichs | Phys Chem Chem Phys | 2005 | 16240044 | Yes |
183 | 5844 | 5844.0 | 179.4 | 179.4 | Modification of seizure activity by electrical stimulation. II. Motor seizure. | R J Racine | Electroencephalogr Clin Neurophysiol | 1972 | 4110397 | Yes |
184 | 5832 | 5832.0 | 76.44 | 76.4 | The Environment And Disease: Association Or Causation? | A B Hill | Proc R Soc Med | 1965 | 14283879 | Yes |
185 | 5749 | 5749.0 | 188.15 | 188.2 | Whatever happened to qualitative description? | M Sandelowski | Res Nurs Health | 2000 | 10940958 | No |
186 | 5734 | 5734.0 | 126.76 | 126.8 | MUSCLE: a multiple sequence alignment method with reduced time and space complexity. | Robert C Edgar | BMC Bioinformatics | 2004 | 15318951 | Yes |
187 | 5722 | 5722.0 | 159.62 | 159.6 | A fast diffeomorphic image registration algorithm. | John Ashburner | Neuroimage | 2007 | 17761438 | Yes |
188 | 5703 | 5703.0 | 142.82 | 142.8 | Apoptosis in the pathogenesis and treatment of disease. | C B Thompson | Science | 1995 | 7878464 | No |
189 | 11403 | 5701.5 | 193.61 | 96.8 | The Carbon Monoxide-Binding Pigment Of Liver Microsomes. I. Evidence For Its Hemoprotein Nature. | T Omura, R Sato | J Biol Chem | 1964 | 14209971 | Yes |
190 | 11395 | 5697.5 | 250.73 | 125.4 | Dendritic cells and the control of immunity. | J Banchereau, R M Steinman | Nature | 1998 | 9521319 | No |
191 | 11286 | 5643.0 | 0.0 | 0.0 | A series of normal stages in the development of the chick embryo. | V Hamburger, H L Hamilton | J Morphol | 1951 | 24539719 | Yes |
192 | 5617 | 5617.0 | 177.61 | 177.6 | jModelTest: phylogenetic model averaging. | David Posada | Mol Biol Evol | 2008 | 18397919 | Yes |
193 | 5606 | 5606.0 | 118.77 | 118.8 | Evaluation of survival data and two new rank order statistics arising in its consideration. | N Mantel | Cancer Chemother Rep | 1966 | 5910392 | Yes |
194 | 5598 | 5598.0 | 137.99 | 138.0 | Development of a rating scale for primary depressive illness. | M Hamilton | Br J Soc Clin Psychol | 1967 | 6080235 | Yes |
195 | 5581 | 5581.0 | 0.0 | 0.0 | Aging: a theory based on free radical and radiation chemistry. | D Harman | J Gerontol | 1956 | 13332224 | Yes |
196 | 5558 | 5558.0 | 221.53 | 221.5 | Orienting of attention. | M I Posner | Q J Exp Psychol | 1980 | 7367577 | Yes |
197 | 5536 | 5536.0 | 92.72 | 92.7 | Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. | F Tietze | Anal Biochem | 1969 | 4388022 | Yes |
198 | 5528 | 5528.0 | 93.03 | 93.0 | Mutation and cancer: statistical study of retinoblastoma. | A G Knudson | Proc Natl Acad Sci U S A | 1971 | 5279523 | Yes |
199 | 11023 | 5511.5 | 365.82 | 182.9 | Operating characteristics of a rank correlation test for publication bias. | C B Begg, M Mazumdar | Biometrics | 1994 | 7786990 | Yes |
200 | 5505 | 5505.0 | 119.02 | 119.0 | The biochemistry of apoptosis. | M O Hengartner | Nature | 2000 | 11048727 | No |
201 | 11005 | 5502.5 | 255.0 | 127.5 | A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. | Stéphane Guindon, Olivier Gascuel | Syst Biol | 2003 | 14530136 | Yes |
202 | 5497 | 5497.0 | 124.5 | 124.5 | Tandem repeats finder: a program to analyze DNA sequences. | G Benson | Nucleic Acids Res | 1999 | 9862982 | Yes |
203 | 16469 | 5489.7 | 495.26 | 165.1 | A simple salting out procedure for extracting DNA from human nucleated cells. | S A Miller, D D Dykes, H F Polesky | Nucleic Acids Res | 1988 | 3344216 | Yes |
204 | 10968 | 5484.0 | 278.92 | 139.5 | Differential expression analysis for sequence count data. | Simon Anders, Wolfgang Huber | Genome Biol | 2010 | 20979621 | Yes |
205 | 10966 | 5483.0 | 231.74 | 115.9 | Inflammation and cancer. | Lisa M Coussens, Zena Werb | Nature | 2002 | 12490959 | No |
206 | 10923 | 5461.5 | 286.91 | 143.5 | Sequencing end-labeled DNA with base-specific chemical cleavages. | A M Maxam, W Gilbert | Methods Enzymol | 1980 | 6246368 | Yes |
207 | 5456 | 5456.0 | 166.57 | 166.6 | Prejudice, social stress, and mental health in lesbian, gay, and bisexual populations: conceptual issues and research evidence. | Ilan H Meyer | Psychol Bull | 2003 | 12956539 | No |
208 | 10886 | 5443.0 | 902.39 | 451.2 | Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. | Zunyou Wu, Jennifer M McGoogan | JAMA | 2020 | 32091533 | Yes |
209 | 5369 | 5369.0 | 141.14 | 141.1 | Mild cognitive impairment as a diagnostic entity. | R C Petersen | J Intern Med | 2004 | 15324362 | No |
210 | 10704 | 5352.0 | 299.61 | 149.8 | MODELTEST: testing the model of DNA substitution. | D Posada, K A Crandall | Bioinformatics | 1998 | 9918953 | Yes |
211 | 5343 | 5343.0 | 202.92 | 202.9 | Revisiting the behavioral model and access to medical care: does it matter? | R M Andersen | J Health Soc Behav | 1995 | 7738325 | Yes |
212 | 5333 | 5333.0 | 157.76 | 157.8 | Developments of a water-maze procedure for studying spatial learning in the rat. | R Morris | J Neurosci Methods | 1984 | 6471907 | Yes |
213 | 5332 | 5332.0 | 136.6 | 136.6 | The Cambridge Structural Database: a quarter of a million crystal structures and rising. | Frank H Allen | Acta Crystallogr B | 2002 | 12037359 | Yes |
214 | 10626 | 5313.0 | 231.54 | 115.8 | MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. | Jürgen Cox, Matthias Mann | Nat Biotechnol | 2008 | 19029910 | Yes |
215 | 15930 | 5310.0 | 596.41 | 198.8 | The positive and negative syndrome scale (PANSS) for schizophrenia. | S R Kay, A Fiszbein, L A Opler | Schizophr Bull | 1987 | 3616518 | Yes |
216 | 5304 | 5304.0 | 102.82 | 102.8 | Epithelial-mesenchymal transitions in tumour progression. | Jean Paul Thiery | Nat Rev Cancer | 2002 | 12189386 | No |
217 | 10605 | 5302.5 | 496.61 | 248.3 | A new depression scale designed to be sensitive to change. | S A Montgomery, M Asberg | Br J Psychiatry | 1979 | 444788 | Yes |
218 | 5299 | 5299.0 | 135.09 | 135.1 | New M13 vectors for cloning. | J Messing | Methods Enzymol | 1983 | 6310323 | Yes |
219 | 10593 | 5296.5 | 0.0 | 0.0 | A quantitative description of membrane current and its application to conduction and excitation in nerve. | A L Hodgkin, A F Huxley | J Physiol | 1952 | 12991237 | Yes |
220 | 26471 | 5294.2 | 714.65 | 142.9 | The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. | J D Thompson, T J Gibson, F Plewniak, F Jeanmougin, D G Higgins | Nucleic Acids Res | 1997 | 9396791 | Yes |
221 | 5291 | 5291.0 | 143.26 | 143.3 | How mitochondria produce reactive oxygen species. | Michael P Murphy | Biochem J | 2009 | 19061483 | No |
222 | 5277 | 5277.0 | 127.45 | 127.5 | The NF-kappa B and I kappa B proteins: new discoveries and insights. | A S Baldwin | Annu Rev Immunol | 1996 | 8717528 | No |
223 | 5261 | 5261.0 | 152.01 | 152.0 | Studies and perspectives of protein kinase C. | Y Nishizuka | Science | 1986 | 3014651 | No |
224 | 31517 | 5252.8 | 1099.88 | 183.3 | Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support. | Paul A Harris, Robert Taylor, Robert Thielke, Jonathon Payne, Nathaniel Gonzalez, Jose G Conde | J Biomed Inform | 2009 | 18929686 | Yes |
225 | 15688 | 5229.3 | 385.97 | 128.7 | Inference of population structure using multilocus genotype data. | J K Pritchard, M Stephens, P Donnelly | Genetics | 2000 | 10835412 | Yes |
226 | 5221 | 5221.0 | 0.0 | 0.0 | [A micro-method of immuno-electrophoresis]. | J J Scheidegger | Int Arch Allergy Appl Immunol | 1955 | 13262900 | Yes |
227 | 5218 | 5218.0 | 53.69 | 53.7 | The Two Histological Main Types Of Gastric Carcinoma: Diffuse And So-Called Intestinal-Type Carcinoma. An Attempt At A Histo-Clinical Classification. | P Lauren | Acta Pathol Microbiol Scand | 1965 | 14320675 | Yes |
228 | 20848 | 5212.0 | 529.66 | 132.4 | Features and development of Coot. | P Emsley, B Lohkamp, W G Scott, K Cowtan | Acta Crystallogr D Biol Crystallogr | 2010 | 20383002 | Yes |
229 | 5203 | 5203.0 | 188.94 | 188.9 | Oxygen-derived free radicals in postischemic tissue injury. | J M McCord | N Engl J Med | 1985 | 2981404 | No |
230 | 5192 | 5192.0 | 68.26 | 68.3 | Selective extraction of polyoma DNA from infected mouse cell cultures. | B Hirt | J Mol Biol | 1967 | 4291934 | Yes |
231 | 10302 | 5151.0 | 365.52 | 182.8 | The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. | R F Furchgott, J V Zawadzki | Nature | 1980 | 6253831 | Yes |
232 | 5142 | 5142.0 | 124.68 | 124.7 | Emotion circuits in the brain. | J E LeDoux | Annu Rev Neurosci | 2000 | 10845062 | No |
233 | 10208 | 5104.0 | 242.17 | 121.1 | Comparative protein modelling by satisfaction of spatial restraints. | A Sali, T L Blundell | J Mol Biol | 1993 | 8254673 | Yes |
234 | 5102 | 5102.0 | 101.45 | 101.5 | Rho GTPases and the actin cytoskeleton. | A Hall | Science | 1998 | 9438836 | No |
235 | 5102 | 5102.0 | 102.05 | 102.0 | Targeting HIF-1 for cancer therapy. | Gregg L Semenza | Nat Rev Cancer | 2003 | 13130303 | No |
236 | 5100 | 5100.0 | 235.39 | 235.4 | Executive functions. | Adele Diamond | Annu Rev Psychol | 2013 | 23020641 | No |
237 | 5097 | 5097.0 | 198.17 | 198.2 | The need for a new medical model: a challenge for biomedicine. | G L Engel | Science | 1977 | 847460 | Yes |
238 | 10194 | 5097.0 | 270.6 | 135.3 | Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. | H Schägger, G von Jagow | Anal Biochem | 1987 | 2449095 | Yes |
239 | 5080 | 5080.0 | 187.15 | 187.2 | Analyzing Tables Of Statistical Tests. | William R Rice | Evolution | 1989 | 28568501 | Yes |
240 | 10158 | 5079.0 | 219.62 | 109.8 | The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. | John Hardy, Dennis J Selkoe | Science | 2002 | 12130773 | No |
241 | 5042 | 5042.0 | 184.04 | 184.0 | FreeSurfer. | Bruce Fischl | Neuroimage | 2012 | 22248573 | No |
242 | 14932 | 4977.3 | 539.78 | 179.9 | Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. | S M Hsu, L Raine, H Fanger | J Histochem Cytochem | 1981 | 6166661 | Yes |
243 | 24854 | 4970.8 | 1071.24 | 214.2 | MEGA6: Molecular Evolutionary Genetics Analysis version 6.0. | Koichiro Tamura, Glen Stecher, Daniel Peterson, Alan Filipski, Sudhir Kumar | Mol Biol Evol | 2013 | 24132122 | Yes |
244 | 14904 | 4968.0 | 994.52 | 331.5 | Cancer statistics, 2019. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2019 | 30620402 | Yes |
245 | 9915 | 4957.5 | 235.8 | 117.9 | A genetic model for colorectal tumorigenesis. | E R Fearon, B Vogelstein | Cell | 1990 | 2188735 | No |
246 | 4951 | 4951.0 | 127.79 | 127.8 | A protein binding assay for adenosine 3':5'-cyclic monophosphate. | A G Gilman | Proc Natl Acad Sci U S A | 1970 | 4318781 | Yes |
247 | 4930 | 4930.0 | 111.33 | 111.3 | The clonal evolution of tumor cell populations. | P C Nowell | Science | 1976 | 959840 | Yes |
248 | 14734 | 4911.3 | 583.6 | 194.5 | A global measure of perceived stress. | S Cohen, T Kamarck, R Mermelstein | J Health Soc Behav | 1983 | 6668417 | Yes |
249 | 4909 | 4909.0 | 156.11 | 156.1 | Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies. | C B Laurell | Anal Biochem | 1966 | 5959431 | Yes |
250 | 9796 | 4898.0 | 350.78 | 175.4 | Ligand: a versatile computerized approach for characterization of ligand-binding systems. | P J Munson, D Rodbard | Anal Biochem | 1980 | 6254391 | Yes |
251 | 4880 | 4880.0 | 148.1 | 148.1 | Traumatic arthritis of the hip after dislocation and acetabular fractures: treatment by mold arthroplasty. An end-result study using a new method of result evaluation. | W H Harris | J Bone Joint Surg Am | 1969 | 5783851 | Yes |
252 | 9751 | 4875.5 | 161.6 | 80.8 | Functional Evaluation: The Barthel Index. | F I Mahoney, D W Barthel | Md State Med J | 1965 | 14258950 | Yes |
253 | 14610 | 4870.0 | 394.01 | 131.3 | Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. | C Yanisch-Perron, J Vieira, J Messing | Gene | 1985 | 2985470 | Yes |
254 | 14598 | 4866.0 | 1207.92 | 402.6 | Cancer statistics, 2020. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2020 | 31912902 | Yes |
255 | 9709 | 4854.5 | 398.09 | 199.0 | phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data. | Paul J McMurdie, Susan Holmes | PLoS One | 2013 | 23630581 | Yes |
256 | 4852 | 4852.0 | 97.84 | 97.8 | An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs. | M Kozak | Nucleic Acids Res | 1987 | 3313277 | No |
257 | 9704 | 4852.0 | 177.65 | 88.8 | Assessment of older people: self-maintaining and instrumental activities of daily living. | M P Lawton, E M Brody | Gerontologist | 1969 | 5349366 | Yes |
258 | 4845 | 4845.0 | 90.17 | 90.2 | DNA methylation patterns and epigenetic memory. | Adrian Bird | Genes Dev | 2002 | 11782440 | No |
259 | 24208 | 4841.6 | 410.97 | 82.2 | An inventory for measuring depression. | A T Beck, C H Ward, M Mendelson, J Mock, J Erbaugh | Arch Gen Psychiatry | 1961 | 13688369 | Yes |
260 | 14446 | 4815.3 | 357.04 | 119.0 | A comprehensive set of sequence analysis programs for the VAX. | J Devereux, P Haeberli, O Smithies | Nucleic Acids Res | 1984 | 6546423 | Yes |
261 | 9615 | 4807.5 | 259.47 | 129.7 | The rise of graphene. | A K Geim, K S Novoselov | Nat Mater | 2007 | 17330084 | Yes |
262 | 9613 | 4806.5 | 326.16 | 163.1 | Qualitative content analysis in nursing research: concepts, procedures and measures to achieve trustworthiness. | U H Graneheim, B Lundman | Nurse Educ Today | 2004 | 14769454 | No |
263 | 14402 | 4800.7 | 0.0 | 0.0 | Determination of serum proteins by means of the biuret reaction. | A G Gornall, C J Bardawill, M M David | J Biol Chem | 1949 | 18110453 | Yes |
264 | 4789 | 4789.0 | 57.49 | 57.5 | Metabolism Of Isolated Fat Cells. I. Effects Of Hormones On Glucose Metabolism And Lipolysis. | M Rodbell | J Biol Chem | 1964 | 14169133 | Yes |
265 | 4785 | 4785.0 | 107.25 | 107.2 | ras oncogenes in human cancer: a review. | J L Bos | Cancer Res | 1989 | 2547513 | No |
266 | 9538 | 4769.0 | 219.09 | 109.5 | Parkinsonism: onset, progression and mortality. | M M Hoehn, M D Yahr | Neurology | 1967 | 6067254 | Yes |
267 | 4765 | 4765.0 | 104.82 | 104.8 | Cancer cell cycles. | C J Sherr | Science | 1996 | 8939849 | No |
268 | 9502 | 4751.0 | 158.5 | 79.2 | A new technique for the assay of infectivity of human adenovirus 5 DNA. | F L Graham, A J van der Eb | Virology | 1973 | 4705382 | Yes |
269 | 9420 | 4710.0 | 236.88 | 118.4 | Improved tools for biological sequence comparison. | W R Pearson, D J Lipman | Proc Natl Acad Sci U S A | 1988 | 3162770 | Yes |
270 | 4699 | 4699.0 | 156.99 | 157.0 | The pathogenesis of atherosclerosis--an update. | R Ross | N Engl J Med | 1986 | 3511384 | No |
271 | 14081 | 4693.7 | 307.08 | 102.4 | Refinement of macromolecular structures by the maximum-likelihood method. | G N Murshudov, A A Vagin, E J Dodson | Acta Crystallogr D Biol Crystallogr | 1997 | 15299926 | Yes |
272 | 4693 | 4693.0 | 199.03 | 199.0 | The McGill Pain Questionnaire: major properties and scoring methods. | Ronald Melzack | Pain | 1975 | 1235985 | Yes |
273 | 14062 | 4687.3 | 485.1 | 161.7 | Nitric oxide: physiology, pathophysiology, and pharmacology. | S Moncada, R M Palmer, E A Higgs | Pharmacol Rev | 1991 | 1852778 | No |
274 | 4682 | 4682.0 | 102.93 | 102.9 | Alzheimer's disease: genes, proteins, and therapy. | D J Selkoe | Physiol Rev | 2001 | 11274343 | No |
275 | 14035 | 4678.3 | 615.82 | 205.3 | Development and validation of brief measures of positive and negative affect: the PANAS scales. | D Watson, L A Clark, A Tellegen | J Pers Soc Psychol | 1988 | 3397865 | Yes |
276 | 4674 | 4674.0 | 261.55 | 261.6 | Aggregation of blood platelets by adenosine diphosphate and its reversal. | G V Born | Nature | 1962 | 13871375 | Yes |
277 | 4673 | 4673.0 | 129.94 | 129.9 | Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes. | P Matsudaira | J Biol Chem | 1987 | 3611052 | Yes |
278 | 4665 | 4665.0 | 40.55 | 40.5 | The Limited In Vitro Lifetime Of Human Diploid Cell Strains. | L Hayflick | Exp Cell Res | 1965 | 14315085 | Yes |
279 | 9313 | 4656.5 | 253.06 | 126.5 | Ab initio molecular dynamics for liquid metals. | G Kresse, J Hafner | Phys Rev B Condens Matter | 1993 | 10004490 | Yes |
280 | 4651 | 4651.0 | 102.86 | 102.9 | Prions. | S B Prusiner | Proc Natl Acad Sci U S A | 1998 | 9811807 | No |
281 | 9289 | 4644.5 | 338.7 | 169.3 | Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models. | Kristopher J Preacher, Andrew F Hayes | Behav Res Methods | 2008 | 18697684 | Yes |
282 | 4642 | 4642.0 | 120.41 | 120.4 | A rapid banding technique for human chromosomes. | M Seabright | Lancet | 1971 | 4107917 | Yes |
283 | 18555 | 4638.8 | 531.86 | 133.0 | MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. | Koichiro Tamura, Joel Dudley, Masatoshi Nei, Sudhir Kumar | Mol Biol Evol | 2007 | 17488738 | Yes |
284 | 13914 | 4638.0 | 454.61 | 151.5 | featureCounts: an efficient general purpose program for assigning sequence reads to genomic features. | Yang Liao, Gordon K Smyth, Wei Shi | Bioinformatics | 2014 | 24227677 | Yes |
285 | 18539 | 4634.8 | 555.13 | 138.8 | clusterProfiler: an R package for comparing biological themes among gene clusters. | Guangchuang Yu, Li-Gen Wang, Yanyan Han, Qing-Yu He | OMICS | 2012 | 22455463 | Yes |
286 | 18485 | 4621.2 | 299.91 | 75.0 | A new and rapid colorimetric determination of acetylcholinesterase activity. | G L Ellman, K D Courtney, V Andres, R M Feather-Stone | Biochem Pharmacol | 1961 | 13726518 | Yes |
287 | 9167 | 4583.5 | 140.35 | 70.2 | Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). | J M McCord, I Fridovich | J Biol Chem | 1969 | 5389100 | Yes |
288 | 4579 | 4579.0 | 93.55 | 93.5 | Alternative activation of macrophages. | Siamon Gordon | Nat Rev Immunol | 2003 | 12511873 | No |
289 | 9153 | 4576.5 | 202.88 | 101.4 | Primer3 on the WWW for general users and for biologist programmers. | S Rozen, H Skaletsky | Methods Mol Biol | 2000 | 10547847 | Yes |
290 | 13692 | 4564.0 | 436.91 | 145.6 | Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. | E R DeLong, D M DeLong, D L Clarke-Pearson | Biometrics | 1988 | 3203132 | Yes |
291 | 4554 | 4554.0 | 141.61 | 141.6 | Updating P300: an integrative theory of P3a and P3b. | John Polich | Clin Neurophysiol | 2007 | 17573239 | No |
292 | 13649 | 4549.7 | 485.2 | 161.7 | HTSeq--a Python framework to work with high-throughput sequencing data. | Simon Anders, Paul Theodor Pyl, Wolfgang Huber | Bioinformatics | 2015 | 25260700 | Yes |
293 | 4521 | 4521.0 | 96.84 | 96.8 | ras genes. | M Barbacid | Annu Rev Biochem | 1987 | 3304147 | No |
294 | 4509 | 4509.0 | 47.36 | 47.4 | The genetical evolution of social behaviour. I. | W D Hamilton | J Theor Biol | 1964 | 5875341 | Yes |
295 | 9017 | 4508.5 | 215.25 | 107.6 | Collective dynamics of 'small-world' networks. | D J Watts, S H Strogatz | Nature | 1998 | 9623998 | Yes |
296 | 4497 | 4497.0 | 103.01 | 103.0 | Cancer. p53, guardian of the genome. | D P Lane | Nature | 1992 | 1614522 | No |
297 | 4491 | 4491.0 | 106.59 | 106.6 | Why most published research findings are false. | John P A Ioannidis | PLoS Med | 2005 | 16060722 | Yes |
298 | 13449 | 4483.0 | 575.8 | 191.9 | Deep learning. | Yann LeCun, Yoshua Bengio, Geoffrey Hinton | Nature | 2015 | 26017442 | No |
299 | 4481 | 4481.0 | 90.43 | 90.4 | Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. | M Kozak | Cell | 1986 | 3943125 | Yes |
300 | 8961 | 4480.5 | 0.0 | 0.0 | A simplified method of evaluating dose-effect experiments. | J T Litchfield, F Wilcoxon | J Pharmacol Exp Ther | 1949 | 18152921 | Yes |
301 | 26756 | 4459.3 | 917.17 | 152.9 | Global cancer statistics. | Ahmedin Jemal, Freddie Bray, Melissa M Center, Jacques Ferlay, Elizabeth Ward, David Forman | CA Cancer J Clin | 2011 | 21296855 | Yes |
302 | 8881 | 4440.5 | 237.63 | 118.8 | A synaptic model of memory: long-term potentiation in the hippocampus. | T V Bliss, G L Collingridge | Nature | 1993 | 8421494 | No |
303 | 4435 | 4435.0 | 107.58 | 107.6 | A new method for predicting signal sequence cleavage sites. | G von Heijne | Nucleic Acids Res | 1986 | 3714490 | Yes |
304 | 4415 | 4415.0 | 90.38 | 90.4 | Wnt/beta-catenin signaling in development and disease. | Hans Clevers | Cell | 2006 | 17081971 | No |
305 | 8829 | 4414.5 | 328.79 | 164.4 | The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay. | I F Benzie, J J Strain | Anal Biochem | 1996 | 8660627 | Yes |
306 | 17657 | 4414.2 | 551.83 | 138.0 | A consistent and accurate ab initio parametrization of density functional dispersion correction (DFT-D) for the 94 elements H-Pu. | Stefan Grimme, Jens Antony, Stephan Ehrlich, Helge Krieg | J Chem Phys | 2010 | 20423165 | Yes |
307 | 8793 | 4396.5 | 203.09 | 101.5 | SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. | N Guex, M C Peitsch | Electrophoresis | 1997 | 9504803 | Yes |
308 | 8791 | 4395.5 | 254.47 | 127.2 | Estimating F-Statistics For The Analysis Of Population Structure. | B S Weir, C Clark Cockerham | Evolution | 1984 | 28563791 | Yes |
309 | 4395 | 4395.0 | 85.21 | 85.2 | The detection of disease clustering and a generalized regression approach. | N Mantel | Cancer Res | 1967 | 6018555 | Yes |
310 | 8784 | 4392.0 | 220.02 | 110.0 | Assessment of coma and impaired consciousness. A practical scale. | G Teasdale, B Jennett | Lancet | 1974 | 4136544 | Yes |
311 | 8766 | 4383.0 | 319.32 | 159.7 | Multiwfn: a multifunctional wavefunction analyzer. | Tian Lu, Feiwu Chen | J Comput Chem | 2012 | 22162017 | Yes |
312 | 8765 | 4382.5 | 161.0 | 80.5 | A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels. | W M Bonner, R A Laskey | Eur J Biochem | 1974 | 4850204 | Yes |
313 | 4374 | 4374.0 | 159.46 | 159.5 | EuroQol: the current state of play. | R Brooks | Health Policy | 1996 | 10158943 | No |
314 | 4372 | 4372.0 | 83.18 | 83.2 | The phosphoinositide 3-kinase pathway. | Lewis C Cantley | Science | 2002 | 12040186 | No |
315 | 8733 | 4366.5 | 361.09 | 180.5 | The timed "Up & Go": a test of basic functional mobility for frail elderly persons. | D Podsiadlo, S Richardson | J Am Geriatr Soc | 1991 | 1991946 | Yes |
316 | 4350 | 4350.0 | 221.5 | 221.5 | Tetramethyl benzidine for horseradish peroxidase neurohistochemistry: a non-carcinogenic blue reaction product with superior sensitivity for visualizing neural afferents and efferents. | M M Mesulam | J Histochem Cytochem | 1978 | 24068 | Yes |
317 | 8699 | 4349.5 | 0.0 | 0.0 | Radiological assessment of osteo-arthrosis. | J H Kellgren, J S Lawrence | Ann Rheum Dis | 1957 | 13498604 | Yes |
318 | 26061 | 4343.5 | 949.28 | 158.2 | MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. | Koichiro Tamura, Daniel Peterson, Nicholas Peterson, Glen Stecher, Masatoshi Nei, Sudhir Kumar | Mol Biol Evol | 2011 | 21546353 | Yes |
319 | 12993 | 4331.0 | 621.4 | 207.1 | Cancer statistics, 2016. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2016 | 26742998 | Yes |
320 | 4330 | 4330.0 | 111.67 | 111.7 | Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. | Y Nishizuka | Science | 1992 | 1411571 | No |
321 | 4324 | 4324.0 | 91.67 | 91.7 | Protein production by auto-induction in high density shaking cultures. | F William Studier | Protein Expr Purif | 2005 | 15915565 | Yes |
322 | 4316 | 4316.0 | 101.14 | 101.1 | Mechanisms of angiogenesis. | W Risau | Nature | 1997 | 9109485 | No |
323 | 4315 | 4315.0 | 161.29 | 161.3 | Measuring the accuracy of diagnostic systems. | J A Swets | Science | 1988 | 3287615 | No |
324 | 12917 | 4305.7 | 736.56 | 245.5 | Cancer statistics, 2018. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2018 | 29313949 | Yes |
325 | 4301 | 4301.0 | 128.47 | 128.5 | Glutamate neurotoxicity and diseases of the nervous system. | D W Choi | Neuron | 1988 | 2908446 | No |
326 | 8581 | 4290.5 | 461.13 | 230.6 | Preparation of iodine-131 labelled human growth hormone of high specific activity. | W M Hunter, F C Greenwood | Nature | 1962 | 14450081 | Yes |
327 | 4288 | 4288.0 | 201.51 | 201.5 | Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs. | Daniël Lakens | Front Psychol | 2013 | 24324449 | No |
328 | 4276 | 4276.0 | 0.0 | 0.0 | New methods for calculating metabolic rate with special reference to protein metabolism. | J B De B Weir | J Physiol | 1949 | 15394301 | Yes |
329 | 4272 | 4272.0 | 113.23 | 113.2 | The molecular heterogeneity of protein kinase C and its implications for cellular regulation. | Y Nishizuka | Nature | 1988 | 3045562 | No |
330 | 4264 | 4264.0 | 0.0 | 0.0 | Evolution in Mendelian Populations. | S Wright | Genetics | 1931 | 17246615 | Yes |
331 | 29847 | 4263.9 | 655.7 | 93.7 | UCSF Chimera--a visualization system for exploratory research and analysis. | Eric F Pettersen, Thomas D Goddard, Conrad C Huang, Gregory S Couch, Daniel M Greenblatt, Elaine C Meng, Thomas E Ferrin | J Comput Chem | 2004 | 15264254 | Yes |
332 | 4262 | 4262.0 | 92.29 | 92.3 | Apoptosis by death factor. | S Nagata | Cell | 1997 | 9039262 | No |
333 | 25548 | 4258.0 | 835.3 | 139.2 | Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. | D R Matthews, J P Hosker, A S Rudenski, B A Naylor, D F Treacher, R C Turner | Diabetologia | 1985 | 3899825 | Yes |
334 | 4240 | 4240.0 | 0.0 | 0.0 | Estimation of nuclear population from microtome sections. | M Abercrombie | Anat Rec | 1946 | 21015608 | Yes |
335 | 4237 | 4237.0 | 0.0 | 0.0 | The colorimetric estimation of formaldehyde by means of the Hantzsch reaction. | T Nash | Biochem J | 1953 | 13105648 | Yes |
336 | 4235 | 4235.0 | 87.52 | 87.5 | The retinoblastoma protein and cell cycle control. | R A Weinberg | Cell | 1995 | 7736585 | No |
337 | 12696 | 4232.0 | 477.2 | 159.1 | HISAT: a fast spliced aligner with low memory requirements. | Daehwan Kim, Ben Langmead, Steven L Salzberg | Nat Methods | 2015 | 25751142 | Yes |
338 | 4228 | 4228.0 | 0.0 | 0.0 | Amino acid metabolism in mammalian cell cultures. | H Eagle | Science | 1959 | 13675766 | Yes |
339 | 4223 | 4223.0 | 131.19 | 131.2 | Emerging adulthood. A theory of development from the late teens through the twenties. | J J Arnett | Am Psychol | 2000 | 10842426 | Yes |
340 | 4221 | 4221.0 | 91.18 | 91.2 | Atherosclerosis. | A J Lusis | Nature | 2000 | 11001066 | No |
341 | 4218 | 4218.0 | 109.65 | 109.7 | Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. | A H Wyllie | Nature | 1980 | 6245367 | Yes |
342 | 12648 | 4216.0 | 469.31 | 156.4 | A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. | J Ware, M Kosinski, S D Keller | Med Care | 1996 | 8628042 | Yes |
343 | 4215 | 4215.0 | 93.85 | 93.8 | Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing. | S Henikoff | Gene | 1984 | 6235151 | Yes |
344 | 4214 | 4214.0 | 75.97 | 76.0 | Generalized lacZ expression with the ROSA26 Cre reporter strain. | P Soriano | Nat Genet | 1999 | 9916792 | Yes |
345 | 37782 | 4198.0 | 954.41 | 106.0 | The Sequence Alignment/Map format and SAMtools. | Heng Li, Bob Handsaker, Alec Wysoker, Tim Fennell, Jue Ruan, Nils Homer, Gabor Marth, Goncalo Abecasis, Richard Durbin | Bioinformatics | 2009 | 19505943 | Yes |
346 | 4196 | 4196.0 | 0.0 | 0.0 | A relation between non-esterified fatty acids in plasma and the metabolism of glucose. | V P Dole | J Clin Invest | 1956 | 13286333 | Yes |
347 | 8387 | 4193.5 | 223.37 | 111.7 | Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. | D E Paglia, W N Valentine | J Lab Clin Med | 1967 | 6066618 | Yes |
348 | 4193 | 4193.0 | 92.89 | 92.9 | PAML: a program package for phylogenetic analysis by maximum likelihood. | Z Yang | Comput Appl Biosci | 1997 | 9367129 | Yes |
349 | 4186 | 4186.0 | 154.25 | 154.2 | A concordance correlation coefficient to evaluate reproducibility. | L I Lin | Biometrics | 1989 | 2720055 | Yes |
350 | 4185 | 4185.0 | 109.05 | 109.0 | Staphylococcus aureus infections. | F D Lowy | N Engl J Med | 1998 | 9709046 | No |
351 | 4179 | 4179.0 | 86.97 | 87.0 | Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. | C J Marshall | Cell | 1995 | 7834738 | No |
352 | 16681 | 4170.2 | 622.65 | 155.7 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | Ann Intern Med | 2009 | 19622511 | No |
353 | 8326 | 4163.0 | 222.48 | 111.2 | Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetii. | Daniel E Voth, Robert A Heinzen | Cell Microbiol | 2007 | 17381428 | No |
354 | 4153 | 4153.0 | 50.75 | 50.8 | Bone: formation by autoinduction. | M R Urist | Science | 1965 | 5319761 | Yes |
355 | 4146 | 4146.0 | 173.21 | 173.2 | Determination of protein: a modification of the Lowry method that gives a linear photometric response. | E F Hartree | Anal Biochem | 1972 | 4115981 | Yes |
356 | 8292 | 4146.0 | 263.99 | 132.0 | DnaSP v5: a software for comprehensive analysis of DNA polymorphism data. | P Librado, J Rozas | Bioinformatics | 2009 | 19346325 | Yes |
357 | 8280 | 4140.0 | 177.66 | 88.8 | Genomic sequencing. | G M Church, W Gilbert | Proc Natl Acad Sci U S A | 1984 | 6326095 | Yes |
358 | 4136 | 4136.0 | 0.0 | 0.0 | The determination of enzyme inhibitor constants. | M Dixon | Biochem J | 1953 | 13093635 | Yes |
359 | 8228 | 4114.0 | 210.97 | 105.5 | tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence. | T M Lowe, S R Eddy | Nucleic Acids Res | 1997 | 9023104 | Yes |
360 | 4099 | 4099.0 | 128.44 | 128.4 | Bacterial evolution. | C R Woese | Microbiol Rev | 1987 | 2439888 | No |
361 | 4090 | 4090.0 | 165.37 | 165.4 | A short portable mental status questionnaire for the assessment of organic brain deficit in elderly patients. | E Pfeiffer | J Am Geriatr Soc | 1975 | 1159263 | Yes |
362 | 4086 | 4086.0 | 84.85 | 84.8 | The green fluorescent protein. | R Y Tsien | Annu Rev Biochem | 1998 | 9759496 | No |
363 | 4067 | 4067.0 | 127.65 | 127.7 | How do you feel--now? The anterior insula and human awareness. | A D Bud Craig | Nat Rev Neurosci | 2009 | 19096369 | No |
364 | 4061 | 4061.0 | 113.15 | 113.2 | The Scree Test For The Number Of Factors. | R B Cattell | Multivariate Behav Res | 1966 | 26828106 | Yes |
365 | 4055 | 4055.0 | 79.19 | 79.2 | Hypoxia--a key regulatory factor in tumour growth. | Adrian L Harris | Nat Rev Cancer | 2002 | 11902584 | No |
366 | 4053 | 4053.0 | 135.68 | 135.7 | Weighted kappa: nominal scale agreement with provision for scaled disagreement or partial credit. | J Cohen | Psychol Bull | 1968 | 19673146 | Yes |
367 | 8080 | 4040.0 | 223.9 | 112.0 | Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. | S Duval, R Tweedie | Biometrics | 2000 | 10877304 | Yes |
368 | 4034 | 4034.0 | 109.49 | 109.5 | Mesenchymal stem cells. | A I Caplan | J Orthop Res | 1991 | 1870029 | Yes |
369 | 12092 | 4030.7 | 609.71 | 203.2 | Cancer Statistics, 2017. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2017 | 28055103 | Yes |
370 | 4010 | 4010.0 | 70.51 | 70.5 | Principles that govern the folding of protein chains. | C B Anfinsen | Science | 1973 | 4124164 | Yes |
371 | 4003 | 4003.0 | 103.59 | 103.6 | Integrins: a family of cell surface receptors. | R O Hynes | Cell | 1987 | 3028640 | No |
372 | 7981 | 3990.5 | 196.09 | 98.0 | Fast and accurate long-read alignment with Burrows-Wheeler transform. | Heng Li, Richard Durbin | Bioinformatics | 2010 | 20080505 | Yes |
373 | 3988 | 3988.0 | 107.21 | 107.2 | What is the evidence that tumors are angiogenesis dependent? | J Folkman | J Natl Cancer Inst | 1990 | 1688381 | No |
374 | 11950 | 3983.3 | 305.42 | 101.8 | Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. | W H Habig, M J Pabst, W B Jakoby | J Biol Chem | 1974 | 4436300 | Yes |
375 | 3983 | 3983.0 | 100.65 | 100.7 | Oxidative stress, antioxidants and stress tolerance. | Ron Mittler | Trends Plant Sci | 2002 | 12234732 | No |
376 | 3981 | 3981.0 | 97.76 | 97.8 | Multiple sequence alignment with hierarchical clustering. | F Corpet | Nucleic Acids Res | 1988 | 2849754 | Yes |
377 | 15922 | 3980.5 | 577.6 | 144.4 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | BMJ | 2009 | 19622551 | No |
378 | 3972 | 3972.0 | 128.43 | 128.4 | Tissue destruction by neutrophils. | S J Weiss | N Engl J Med | 1989 | 2536474 | No |
379 | 3971 | 3971.0 | 105.18 | 105.2 | Observational study of behavior: sampling methods. | J Altmann | Behaviour | 1974 | 4597405 | No |
380 | 7935 | 3967.5 | 150.08 | 75.0 | A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. | R S Sikorski, P Hieter | Genetics | 1989 | 2659436 | Yes |
381 | 3964 | 3964.0 | 0.0 | 0.0 | Staining of tissue sections for electron microscopy with heavy metals. | M L Watson | J Biophys Biochem Cytol | 1958 | 13563554 | Yes |
382 | 19788 | 3957.6 | 769.94 | 154.0 | The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. | D J Buysse, C F Reynolds, T H Monk, S R Berman, D J Kupfer | Psychiatry Res | 1989 | 2748771 | Yes |
383 | 7908 | 3954.0 | 200.99 | 100.5 | Control of goal-directed and stimulus-driven attention in the brain. | Maurizio Corbetta, Gordon L Shulman | Nat Rev Neurosci | 2002 | 11994752 | No |
384 | 3948 | 3948.0 | 104.76 | 104.8 | Propensity score methods for bias reduction in the comparison of a treatment to a non-randomized control group. | R B D'Agostino | Stat Med | 1998 | 9802183 | Yes |
385 | 3943 | 3943.0 | 114.8 | 114.8 | Soft self-consistent pseudopotentials in a generalized eigenvalue formalism. | D Vanderbilt | Phys Rev B Condens Matter | 1990 | 9993096 | Yes |
386 | 3938 | 3938.0 | 85.34 | 85.3 | Folding DNA to create nanoscale shapes and patterns. | Paul W K Rothemund | Nature | 2006 | 16541064 | Yes |
387 | 3930 | 3930.0 | 103.57 | 103.6 | Drug combination studies and their synergy quantification using the Chou-Talalay method. | Ting-Chao Chou | Cancer Res | 2010 | 20068163 | Yes |
388 | 3925 | 3925.0 | 84.18 | 84.2 | Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. | Rakesh K Jain | Science | 2005 | 15637262 | No |
389 | 3925 | 3925.0 | 110.25 | 110.2 | Functions of DNA methylation: islands, start sites, gene bodies and beyond. | Peter A Jones | Nat Rev Genet | 2012 | 22641018 | No |
390 | 7849 | 3924.5 | 261.2 | 130.6 | FLASH: fast length adjustment of short reads to improve genome assemblies. | Tanja Magoč, Steven L Salzberg | Bioinformatics | 2011 | 21903629 | Yes |
391 | 7848 | 3924.0 | 218.97 | 109.5 | Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose. | H Aviv, P Leder | Proc Natl Acad Sci U S A | 1972 | 4504350 | Yes |
392 | 3922 | 3922.0 | 103.93 | 103.9 | A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data. | Heng Li | Bioinformatics | 2011 | 21903627 | Yes |
393 | 11743 | 3914.3 | 315.92 | 105.3 | Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. | J F Kerr, A H Wyllie, A R Currie | Br J Cancer | 1972 | 4561027 | No |
394 | 3909 | 3909.0 | 63.83 | 63.8 | Disc Electrophoresis. I. Background And Theory. | L Ornstein | Ann N Y Acad Sci | 1964 | 14240533 | Yes |
395 | 3907 | 3907.0 | 120.55 | 120.5 | Nitric oxide as a secretory product of mammalian cells. | C Nathan | FASEB J | 1992 | 1381691 | No |
396 | 3907 | 3907.0 | 80.59 | 80.6 | Protein secondary structure prediction based on position-specific scoring matrices. | D T Jones | J Mol Biol | 1999 | 10493868 | Yes |
397 | 7793 | 3896.5 | 147.1 | 73.5 | Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. | A H Brand, N Perrimon | Development | 1993 | 8223268 | Yes |
398 | 15580 | 3895.0 | 361.29 | 90.3 | Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. | Ben Langmead, Cole Trapnell, Mihai Pop, Steven L Salzberg | Genome Biol | 2009 | 19261174 | Yes |
399 | 3879 | 3879.0 | 123.11 | 123.1 | Pharmacological implications of microsomal enzyme induction. | A H Conney | Pharmacol Rev | 1967 | 4383307 | Yes |
400 | 15512 | 3878.0 | 496.92 | 124.2 | A brief measure for assessing generalized anxiety disorder: the GAD-7. | Robert L Spitzer, Kurt Kroenke, Janet B W Williams, Bernd Löwe | Arch Intern Med | 2006 | 16717171 | Yes |
401 | 7756 | 3878.0 | 309.85 | 154.9 | The qualitative content analysis process. | Satu Elo, Helvi Kyngäs | J Adv Nurs | 2008 | 18352969 | Yes |
402 | 3878 | 3878.0 | 112.19 | 112.2 | Accelerated Profile HMM Searches. | Sean R Eddy | PLoS Comput Biol | 2011 | 22039361 | Yes |
403 | 3877 | 3877.0 | 95.37 | 95.4 | Origin and physiological roles of inflammation. | Ruslan Medzhitov | Nature | 2008 | 18650913 | No |
404 | 3862 | 3862.0 | 128.19 | 128.2 | Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD. | Russell A Barkley | Psychol Bull | 1997 | 9000892 | No |
405 | 3852 | 3852.0 | 119.18 | 119.2 | DNA methylation age of human tissues and cell types. | Steve Horvath | Genome Biol | 2013 | 24138928 | Yes |
406 | 3848 | 3848.0 | 124.96 | 125.0 | Preparation of isolated rat liver cells. | P O Seglen | Methods Cell Biol | 1976 | 177845 | No |
407 | 3842 | 3842.0 | 97.93 | 97.9 | Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? | Kim A Brogden | Nat Rev Microbiol | 2005 | 15703760 | No |
408 | 7683 | 3841.5 | 169.67 | 84.8 | Inference of macromolecular assemblies from crystalline state. | Evgeny Krissinel, Kim Henrick | J Mol Biol | 2007 | 17681537 | Yes |
409 | 3840 | 3840.0 | 95.75 | 95.8 | The origins and the future of microfluidics. | George M Whitesides | Nature | 2006 | 16871203 | No |
410 | 3836 | 3836.0 | 96.54 | 96.5 | Sequencing technologies - the next generation. | Michael L Metzker | Nat Rev Genet | 2010 | 19997069 | No |
411 | 3822 | 3822.0 | 84.79 | 84.8 | Instability and decay of the primary structure of DNA. | T Lindahl | Nature | 1993 | 8469282 | No |
412 | 3820 | 3820.0 | 80.99 | 81.0 | Scaling and assessment of data quality. | Philip Evans | Acta Crystallogr D Biol Crystallogr | 2006 | 16369096 | No |
413 | 3815 | 3815.0 | 103.19 | 103.2 | Revisions in the International System for Staging Lung Cancer. | C F Mountain | Chest | 1997 | 9187198 | Yes |
414 | 3807 | 3807.0 | 90.63 | 90.6 | Caspases: the executioners of apoptosis. | G M Cohen | Biochem J | 1997 | 9337844 | No |
415 | 3806 | 3806.0 | 109.04 | 109.0 | Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity-score matched samples. | Peter C Austin | Stat Med | 2009 | 19757444 | Yes |
416 | 3802 | 3802.0 | 74.49 | 74.5 | Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. | G R Martin | Proc Natl Acad Sci U S A | 1981 | 6950406 | Yes |
417 | 3798 | 3798.0 | 141.41 | 141.4 | Generalized expectancies for internal versus external control of reinforcement. | J B Rotter | Psychol Monogr | 1966 | 5340840 | No |
418 | 3793 | 3793.0 | 79.64 | 79.6 | A catalogue of splice junction sequences. | S M Mount | Nucleic Acids Res | 1982 | 7063411 | Yes |
419 | 3792 | 3792.0 | 119.66 | 119.7 | genepop'007: a complete re-implementation of the genepop software for Windows and Linux. | François Rousset | Mol Ecol Resour | 2008 | 21585727 | Yes |
420 | 7578 | 3789.0 | 190.03 | 95.0 | The basics of epithelial-mesenchymal transition. | Raghu Kalluri, Robert A Weinberg | J Clin Invest | 2009 | 19487818 | No |
421 | 7566 | 3783.0 | 181.68 | 90.8 | The plant immune system. | Jonathan D G Jones, Jeffery L Dangl | Nature | 2006 | 17108957 | No |
422 | 7559 | 3779.5 | 209.33 | 104.7 | BEAST: Bayesian evolutionary analysis by sampling trees. | Alexei J Drummond, Andrew Rambaut | BMC Evol Biol | 2007 | 17996036 | Yes |
423 | 3777 | 3777.0 | 87.52 | 87.5 | Novel proteinaceous infectious particles cause scrapie. | S B Prusiner | Science | 1982 | 6801762 | Yes |
424 | 3772 | 3772.0 | 77.54 | 77.5 | TGF-beta signal transduction. | J Massagué | Annu Rev Biochem | 1998 | 9759503 | No |
425 | 3759 | 3759.0 | 94.69 | 94.7 | RELION: implementation of a Bayesian approach to cryo-EM structure determination. | Sjors H W Scheres | J Struct Biol | 2012 | 23000701 | Yes |
426 | 3757 | 3757.0 | 65.34 | 65.3 | Estimation of the molecular weights of proteins by Sephadex gel-filtration. | P Andrews | Biochem J | 1964 | 4158310 | Yes |
427 | 7514 | 3757.0 | 180.95 | 90.5 | Mitochondria and apoptosis. | D R Green, J C Reed | Science | 1998 | 9721092 | No |
428 | 3755 | 3755.0 | 108.4 | 108.4 | What's wrong with Bonferroni adjustments. | T V Perneger | BMJ | 1998 | 9553006 | No |
429 | 3752 | 3752.0 | 89.22 | 89.2 | Free R value: a novel statistical quantity for assessing the accuracy of crystal structures. | A T Brünger | Nature | 1992 | 18481394 | Yes |
430 | 3750 | 3750.0 | 170.16 | 170.2 | Basic principles of ROC analysis. | C E Metz | Semin Nucl Med | 1978 | 112681 | Yes |
431 | 3746 | 3746.0 | 107.19 | 107.2 | Silver stain for proteins in polyacrylamide gels: a modified procedure with enhanced uniform sensitivity. | J H Morrissey | Anal Biochem | 1981 | 6172996 | Yes |
432 | 11229 | 3743.0 | 215.48 | 71.8 | Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. | J D Dignam, R M Lebovitz, R G Roeder | Nucleic Acids Res | 1983 | 6828386 | Yes |
433 | 7465 | 3732.5 | 255.49 | 127.7 | Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. | Laurent Excoffier, Heidi E L Lischer | Mol Ecol Resour | 2010 | 21565059 | Yes |
434 | 14899 | 3724.8 | 383.35 | 95.8 | Global cancer statistics, 2002. | D Max Parkin, Freddie Bray, J Ferlay, Paola Pisani | CA Cancer J Clin | 2005 | 15761078 | Yes |
435 | 3709 | 3709.0 | 86.27 | 86.3 | Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. | Ting-Chao Chou | Pharmacol Rev | 2006 | 16968952 | No |
436 | 3703 | 3703.0 | 68.34 | 68.3 | A membrane-filter technique for the detection of complementary DNA. | D T Denhardt | Biochem Biophys Res Commun | 1966 | 5963888 | Yes |
437 | 7394 | 3697.0 | 185.4 | 92.7 | An integrative theory of prefrontal cortex function. | E K Miller, J D Cohen | Annu Rev Neurosci | 2001 | 11283309 | No |
438 | 3696 | 3696.0 | 106.03 | 106.0 | Protective and damaging effects of stress mediators. | B S McEwen | N Engl J Med | 1998 | 9428819 | No |
439 | 3694 | 3694.0 | 535.65 | 535.6 | Hallmarks of Cancer: New Dimensions. | Douglas Hanahan | Cancer Discov | 2022 | 35022204 | No |
440 | 3688 | 3688.0 | 66.21 | 66.2 | Somatic generation of antibody diversity. | S Tonegawa | Nature | 1983 | 6300689 | No |
441 | 3687 | 3687.0 | 103.74 | 103.7 | EEG alpha and theta oscillations reflect cognitive and memory performance: a review and analysis. | W Klimesch | Brain Res Brain Res Rev | 1999 | 10209231 | No |
442 | 7352 | 3676.0 | 161.69 | 80.8 | Functional rafts in cell membranes. | K Simons, E Ikonen | Nature | 1997 | 9177342 | No |
443 | 3672 | 3672.0 | 88.62 | 88.6 | I-TASSER server for protein 3D structure prediction. | Yang Zhang | BMC Bioinformatics | 2008 | 18215316 | Yes |
444 | 7317 | 3658.5 | 184.42 | 92.2 | Long short-term memory. | S Hochreiter, J Schmidhuber | Neural Comput | 1997 | 9377276 | Yes |
445 | 3654 | 3654.0 | 102.93 | 102.9 | Graphene: status and prospects. | A K Geim | Science | 2009 | 19541989 | Yes |
446 | 3650 | 3650.0 | 95.02 | 95.0 | The adolescent brain and age-related behavioral manifestations. | L P Spear | Neurosci Biobehav Rev | 2000 | 10817843 | No |
447 | 3641 | 3641.0 | 100.67 | 100.7 | Biological roles of oligosaccharides: all of the theories are correct. | A Varki | Glycobiology | 1993 | 8490246 | No |
448 | 7235 | 3617.5 | 203.66 | 101.8 | The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique. | R C Graham, M J Karnovsky | J Histochem Cytochem | 1966 | 5962951 | Yes |
449 | 21651 | 3608.5 | 967.38 | 161.2 | Global cancer statistics, 2012. | Lindsey A Torre, Freddie Bray, Rebecca L Siegel, Jacques Ferlay, Joannie Lortet-Tieulent, Ahmedin Jemal | CA Cancer J Clin | 2015 | 25651787 | Yes |
450 | 3605 | 3605.0 | 84.72 | 84.7 | Marrow stromal cells as stem cells for nonhematopoietic tissues. | D J Prockop | Science | 1997 | 9082988 | No |
451 | 3602 | 3602.0 | 107.97 | 108.0 | Inositol trisphosphate and diacylglycerol as second messengers. | M J Berridge | Biochem J | 1984 | 6146314 | No |
452 | 17937 | 3587.4 | 1206.96 | 241.4 | MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms. | Sudhir Kumar, Glen Stecher, Michael Li, Christina Knyaz, Koichiro Tamura | Mol Biol Evol | 2018 | 29722887 | Yes |
453 | 3584 | 3584.0 | 85.53 | 85.5 | Neural networks and physical systems with emergent collective computational abilities. | J J Hopfield | Proc Natl Acad Sci U S A | 1982 | 6953413 | Yes |
454 | 3581 | 3581.0 | 74.86 | 74.9 | Profile hidden Markov models. | S R Eddy | Bioinformatics | 1998 | 9918945 | No |
455 | 10732 | 3577.3 | 258.24 | 86.1 | Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. | Da Wei Huang, Brad T Sherman, Richard A Lempicki | Nucleic Acids Res | 2009 | 19033363 | Yes |
456 | 3575 | 3575.0 | 97.48 | 97.5 | Non-coding RNAs in human disease. | Manel Esteller | Nat Rev Genet | 2011 | 22094949 | No |
457 | 3569 | 3569.0 | 109.08 | 109.1 | Health promotion by social cognitive means. | Albert Bandura | Health Educ Behav | 2004 | 15090118 | Yes |
458 | 10685 | 3561.7 | 262.38 | 87.5 | Understanding the Warburg effect: the metabolic requirements of cell proliferation. | Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson | Science | 2009 | 19460998 | No |
459 | 3553 | 3553.0 | 70.92 | 70.9 | Mammalian neural stem cells. | F H Gage | Science | 2000 | 10688783 | No |
460 | 3549 | 3549.0 | 164.59 | 164.6 | Estimation of average heterozygosity and genetic distance from a small number of individuals. | M Nei | Genetics | 1978 | 17248844 | Yes |
461 | 3543 | 3543.0 | 109.77 | 109.8 | Psychometric properties of the strengths and difficulties questionnaire. | R Goodman | J Am Acad Child Adolesc Psychiatry | 2001 | 11699809 | Yes |
462 | 7079 | 3539.5 | 127.4 | 63.7 | Translating the histone code. | T Jenuwein, C D Allis | Science | 2001 | 11498575 | No |
463 | 3533 | 3533.0 | 80.09 | 80.1 | Nonalcoholic fatty liver disease. | Paul Angulo | N Engl J Med | 2002 | 11961152 | No |
464 | 3525 | 3525.0 | 113.6 | 113.6 | Modeling valuations for EuroQol health states. | P Dolan | Med Care | 1997 | 9366889 | Yes |
465 | 3525 | 3525.0 | 87.01 | 87.0 | How do you feel? Interoception: the sense of the physiological condition of the body. | A D Craig | Nat Rev Neurosci | 2002 | 12154366 | No |
466 | 3524 | 3524.0 | 54.21 | 54.2 | Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. | J D Rowley | Nature | 1973 | 4126434 | Yes |
467 | 3523 | 3523.0 | 66.7 | 66.7 | Signal transduction by the JNK group of MAP kinases. | R J Davis | Cell | 2000 | 11057897 | No |
468 | 7039 | 3519.5 | 350.29 | 175.1 | Receptive fields, binocular interaction and functional architecture in the cat's visual cortex. | D H Hubel, T N Wiesel | J Physiol | 1962 | 14449617 | Yes |
469 | 3517 | 3517.0 | 105.02 | 105.0 | Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans. | L R Squire | Psychol Rev | 1992 | 1594723 | No |
470 | 7031 | 3515.5 | 145.24 | 72.6 | A new method for sequencing DNA. | A M Maxam, W Gilbert | Proc Natl Acad Sci U S A | 1977 | 265521 | Yes |
471 | 3513 | 3513.0 | 80.13 | 80.1 | Glutamate uptake. | N C Danbolt | Prog Neurobiol | 2001 | 11369436 | No |
472 | 3513 | 3513.0 | 61.75 | 61.8 | Automated electron microscope tomography using robust prediction of specimen movements. | David N Mastronarde | J Struct Biol | 2005 | 16182563 | Yes |
473 | 7024 | 3512.0 | 359.0 | 179.5 | Microsomal lipid peroxidation. | J A Buege, S D Aust | Methods Enzymol | 1978 | 672633 | Yes |
474 | 3512 | 3512.0 | 129.11 | 129.1 | You want to measure coping but your protocol's too long: consider the brief COPE. | C S Carver | Int J Behav Med | 1997 | 16250744 | Yes |
475 | 3508 | 3508.0 | 87.24 | 87.2 | The pathobiology of diabetic complications: a unifying mechanism. | Michael Brownlee | Diabetes | 2005 | 15919781 | No |
476 | 17535 | 3507.0 | 496.04 | 99.2 | Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. | O P Hamill, A Marty, E Neher, B Sakmann, F J Sigworth | Pflugers Arch | 1981 | 6270629 | Yes |
477 | 3503 | 3503.0 | 90.99 | 91.0 | Microglia: a sensor for pathological events in the CNS. | G W Kreutzberg | Trends Neurosci | 1996 | 8843599 | No |
478 | 3500 | 3500.0 | 0.0 | 0.0 | The magical number seven plus or minus two: some limits on our capacity for processing information. | G A Miller | Psychol Rev | 1956 | 13310704 | Yes |
479 | 3499 | 3499.0 | 157.01 | 157.0 | The quality of care. How can it be assessed? | A Donabedian | JAMA | 1988 | 3045356 | No |
480 | 3499 | 3499.0 | 56.79 | 56.8 | Spectroscopic determination of tryptophan and tyrosine in proteins. | H Edelhoch | Biochemistry | 1967 | 6049437 | Yes |
481 | 3498 | 3498.0 | 103.89 | 103.9 | adegenet: a R package for the multivariate analysis of genetic markers. | Thibaut Jombart | Bioinformatics | 2008 | 18397895 | Yes |
482 | 3488 | 3488.0 | 58.9 | 58.9 | Statistical estimations in enzyme kinetics. | G N Wilkinson | Biochem J | 1961 | 13785321 | Yes |
483 | 3482 | 3482.0 | 84.86 | 84.9 | The heat-shock response. | S Lindquist | Annu Rev Biochem | 1986 | 2427013 | No |
484 | 3478 | 3478.0 | 51.85 | 51.9 | The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. | J F Woessner | Arch Biochem Biophys | 1961 | 13786180 | Yes |
485 | 10432 | 3477.3 | 389.94 | 130.0 | Cancer statistics, 2013. | Rebecca Siegel, Deepa Naishadham, Ahmedin Jemal | CA Cancer J Clin | 2013 | 23335087 | Yes |
486 | 3471 | 3471.0 | 80.82 | 80.8 | The dendritic cell system and its role in immunogenicity. | R M Steinman | Annu Rev Immunol | 1991 | 1910679 | No |
487 | 3470 | 3470.0 | 135.43 | 135.4 | Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. | O W Griffith | Anal Biochem | 1980 | 7416462 | Yes |
488 | 6914 | 3457.0 | 135.82 | 67.9 | Statistical significance for genomewide studies. | John D Storey, Robert Tibshirani | Proc Natl Acad Sci U S A | 2003 | 12883005 | Yes |
489 | 3454 | 3454.0 | 75.02 | 75.0 | Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. | H F Dvorak | N Engl J Med | 1986 | 3537791 | No |
490 | 3453 | 3453.0 | 93.95 | 94.0 | Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. | R W Mahley | Science | 1988 | 3283935 | No |
491 | 3453 | 3453.0 | 87.04 | 87.0 | Biologic basis for interleukin-1 in disease. | C A Dinarello | Blood | 1996 | 8630372 | No |
492 | 3441 | 3441.0 | 110.42 | 110.4 | No adjustments are needed for multiple comparisons. | K J Rothman | Epidemiology | 1990 | 2081237 | Yes |
493 | 6871 | 3435.5 | 162.64 | 81.3 | "A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum. | A P Feinberg, B Vogelstein | Anal Biochem | 1984 | 6329026 | Yes |
494 | 10272 | 3424.0 | 445.86 | 148.6 | Cancer statistics, 2015. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2015 | 25559415 | Yes |
495 | 6810 | 3405.0 | 172.36 | 86.2 | TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. | T R Mosmann, R L Coffman | Annu Rev Immunol | 1989 | 2523712 | No |
496 | 3394 | 3394.0 | 82.7 | 82.7 | The basis of anisotropic water diffusion in the nervous system - a technical review. | Christian Beaulieu | NMR Biomed | 2002 | 12489094 | No |
497 | 6778 | 3389.0 | 184.81 | 92.4 | Velvet: algorithms for de novo short read assembly using de Bruijn graphs. | Daniel R Zerbino, Ewan Birney | Genome Res | 2008 | 18349386 | Yes |
498 | 3384 | 3384.0 | 0.0 | 0.0 | Some factors in the interpretation of protein denaturation. | W Kauzmann | Adv Protein Chem | 1959 | 14404936 | Yes |
499 | 10139 | 3379.7 | 98.21 | 32.7 | The Preparation Of I-131-Labelled Human Growth Hormone Of High Specific Radioactivity. | F C Greenwood, W M Hunter, J S Glover | Biochem J | 1963 | 14097352 | Yes |
500 | 6746 | 3373.0 | 207.59 | 103.8 | The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. | Stephen B Edge, Carolyn C Compton | Ann Surg Oncol | 2010 | 20180029 | No |
501 | 6744 | 3372.0 | 159.66 | 79.8 | Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. | C Tuerk, L Gold | Science | 1990 | 2200121 | Yes |
502 | 6744 | 3372.0 | 129.13 | 64.6 | The ubiquitin system. | A Hershko, A Ciechanover | Annu Rev Biochem | 1998 | 9759494 | No |
503 | 10102 | 3367.3 | 356.98 | 119.0 | Cancer statistics, 2012. | Rebecca Siegel, Deepa Naishadham, Ahmedin Jemal | CA Cancer J Clin | 2012 | 22237781 | Yes |
504 | 3366 | 3366.0 | 76.64 | 76.6 | Tolerance, danger, and the extended family. | P Matzinger | Annu Rev Immunol | 1994 | 8011301 | No |
505 | 3353 | 3353.0 | 68.69 | 68.7 | The scanning model for translation: an update. | M Kozak | J Cell Biol | 1989 | 2645293 | No |
506 | 3347 | 3347.0 | 94.12 | 94.1 | Room-Temperature Ionic Liquids. Solvents for Synthesis and Catalysis. | Thomas Welton | Chem Rev | 1999 | 11849019 | Yes |
507 | 6680 | 3340.0 | 141.81 | 70.9 | Angiogenesis in cancer and other diseases. | P Carmeliet, R K Jain | Nature | 2000 | 11001068 | No |
508 | 6675 | 3337.5 | 159.58 | 79.8 | Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. | Weizhong Li, Adam Godzik | Bioinformatics | 2006 | 16731699 | Yes |
509 | 3325 | 3325.0 | 68.0 | 68.0 | Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs. | M Kozak | Nucleic Acids Res | 1984 | 6694911 | Yes |
510 | 3325 | 3325.0 | 80.13 | 80.1 | Wound healing--aiming for perfect skin regeneration. | P Martin | Science | 1997 | 9082989 | No |
511 | 3303 | 3303.0 | 83.95 | 84.0 | Gene regulation by steroid hormones. | M Beato | Cell | 1989 | 2644044 | No |
512 | 3302 | 3302.0 | 89.57 | 89.6 | Hay fever, hygiene, and household size. | D P Strachan | BMJ | 1989 | 2513902 | Yes |
513 | 3301 | 3301.0 | 64.4 | 64.4 | The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. | Isaiah J Fidler | Nat Rev Cancer | 2003 | 12778135 | No |
514 | 6601 | 3300.5 | 205.64 | 102.8 | Complex network measures of brain connectivity: uses and interpretations. | Mikail Rubinov, Olaf Sporns | Neuroimage | 2010 | 19819337 | Yes |
515 | 3300 | 3300.0 | 46.33 | 46.3 | Equilibrium Ultracentrifugation Of Dilute Solutions. | D A Yphantis | Biochemistry | 1964 | 14155091 | Yes |
516 | 6594 | 3297.0 | 206.88 | 103.4 | Human malaria parasites in continuous culture. | W Trager, J B Jensen | Science | 1976 | 781840 | Yes |
517 | 3294 | 3294.0 | 117.85 | 117.8 | Quantifying test-retest reliability using the intraclass correlation coefficient and the SEM. | Joseph P Weir | J Strength Cond Res | 2005 | 15705040 | No |
518 | 3288 | 3288.0 | 85.87 | 85.9 | Accurate Coulomb-fitting basis sets for H to Rn. | Florian Weigend | Phys Chem Chem Phys | 2006 | 16633586 | Yes |
519 | 3285 | 3285.0 | 67.01 | 67.0 | Alzheimer's disease is a synaptic failure. | Dennis J Selkoe | Science | 2002 | 12399581 | No |
520 | 6566 | 3283.0 | 178.3 | 89.2 | Projections of global mortality and burden of disease from 2002 to 2030. | Colin D Mathers, Dejan Loncar | PLoS Med | 2006 | 17132052 | Yes |
521 | 6561 | 3280.5 | 216.93 | 108.5 | Management of hepatocellular carcinoma: an update. | Jordi Bruix, Morris Sherman | Hepatology | 2011 | 21374666 | No |
522 | 29462 | 3273.6 | 633.09 | 70.3 | Cytoscape: a software environment for integrated models of biomolecular interaction networks. | Paul Shannon, Andrew Markiel, Owen Ozier, Nitin S Baliga, Jonathan T Wang, Daniel Ramage, Nada Amin, Benno Schwikowski, Trey Ideker | Genome Res | 2003 | 14597658 | Yes |
523 | 3270 | 3270.0 | 86.97 | 87.0 | ABC transporters: from microorganisms to man. | C F Higgins | Annu Rev Cell Biol | 1992 | 1282354 | No |
524 | 3270 | 3270.0 | 109.92 | 109.9 | Transformed up-down methods in psychoacoustics. | H Levitt | J Acoust Soc Am | 1971 | 5541744 | Yes |
525 | 3270 | 3270.0 | 73.94 | 73.9 | Mitochondrial formation of reactive oxygen species. | Julio F Turrens | J Physiol | 2003 | 14561818 | No |
526 | 3267 | 3267.0 | 59.91 | 59.9 | Cell signaling by receptor tyrosine kinases. | J Schlessinger | Cell | 2000 | 11057895 | No |
527 | 6531 | 3265.5 | 197.31 | 98.7 | Superoxide dismutase: improved assays and an assay applicable to acrylamide gels. | C Beauchamp, I Fridovich | Anal Biochem | 1971 | 4943714 | Yes |
528 | 3253 | 3253.0 | 76.15 | 76.2 | Photoelectrochemical cells. | M Grätzel | Nature | 2001 | 11713540 | Yes |
529 | 3253 | 3253.0 | 104.09 | 104.1 | Essential oils: their antibacterial properties and potential applications in foods--a review. | Sara Burt | Int J Food Microbiol | 2004 | 15246235 | No |
530 | 13008 | 3252.0 | 300.67 | 75.2 | Improved methods for building protein models in electron density maps and the location of errors in these models. | T A Jones, J Y Zou, S W Cowan, M Kjeldgaard | Acta Crystallogr A | 1991 | 2025413 | Yes |
531 | 3248 | 3248.0 | 68.07 | 68.1 | Cardiac excitation-contraction coupling. | Donald M Bers | Nature | 2002 | 11805843 | No |
532 | 3247 | 3247.0 | 98.68 | 98.7 | Development of a classification system for periodontal diseases and conditions. | G C Armitage | Ann Periodontol | 1999 | 10863370 | No |
533 | 3239 | 3239.0 | 93.82 | 93.8 | Inositol trisphosphate and diacylglycerol: two interacting second messengers. | M J Berridge | Annu Rev Biochem | 1987 | 3304132 | No |
534 | 3236 | 3236.0 | 120.18 | 120.2 | KDIGO clinical practice guidelines for acute kidney injury. | Arif Khwaja | Nephron Clin Pract | 2012 | 22890468 | No |
535 | 3233 | 3233.0 | 63.79 | 63.8 | STATs and gene regulation. | J E Darnell | Science | 1997 | 9287210 | No |
536 | 3225 | 3225.0 | 69.26 | 69.3 | Activators and target genes of Rel/NF-kappaB transcription factors. | H L Pahl | Oncogene | 1999 | 10602461 | No |
537 | 6447 | 3223.5 | 201.33 | 100.7 | Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees. | K Tamura, M Nei | Mol Biol Evol | 1993 | 8336541 | Yes |
538 | 9631 | 3210.3 | 234.73 | 78.2 | ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. | Kai Wang, Mingyao Li, Hakon Hakonarson | Nucleic Acids Res | 2010 | 20601685 | Yes |
539 | 6412 | 3206.0 | 154.29 | 77.1 | Exploring the full spectrum of macrophage activation. | David M Mosser, Justin P Edwards | Nat Rev Immunol | 2008 | 19029990 | No |
540 | 3200 | 3200.0 | 65.35 | 65.3 | CpG-rich islands and the function of DNA methylation. | A P Bird | Nature | 1986 | 2423876 | No |
541 | 3198 | 3198.0 | 92.46 | 92.5 | Improving the quality of Web surveys: the Checklist for Reporting Results of Internet E-Surveys (CHERRIES). | Gunther Eysenbach | J Med Internet Res | 2004 | 15471760 | No |
542 | 3193 | 3193.0 | 110.76 | 110.8 | The Danish Civil Registration System. | Carsten Bøcker Pedersen | Scand J Public Health | 2011 | 21775345 | Yes |
543 | 3190 | 3190.0 | 66.09 | 66.1 | Protein folding and misfolding. | Christopher M Dobson | Nature | 2003 | 14685248 | No |
544 | 6377 | 3188.5 | 185.16 | 92.6 | Complex brain networks: graph theoretical analysis of structural and functional systems. | Ed Bullmore, Olaf Sporns | Nat Rev Neurosci | 2009 | 19190637 | No |
545 | 3183 | 3183.0 | 91.62 | 91.6 | Statistical tests of neutrality of mutations against population growth, hitchhiking and background selection. | Y X Fu | Genetics | 1997 | 9335623 | Yes |
546 | 12705 | 3176.2 | 462.05 | 115.5 | Statistical power analyses using G*Power 3.1: tests for correlation and regression analyses. | Franz Faul, Edgar Erdfelder, Axel Buchner, Albert-Georg Lang | Behav Res Methods | 2009 | 19897823 | Yes |
547 | 6350 | 3175.0 | 201.25 | 100.6 | Self-determination theory and the facilitation of intrinsic motivation, social development, and well-being. | R M Ryan, E L Deci | Am Psychol | 2000 | 11392867 | Yes |
548 | 28541 | 3171.2 | 900.38 | 100.0 | STAR: ultrafast universal RNA-seq aligner. | Alexander Dobin, Carrie A Davis, Felix Schlesinger, Jorg Drenkow, Chris Zaleski, Sonali Jha, Philippe Batut, Mark Chaisson, Thomas R Gingeras | Bioinformatics | 2013 | 23104886 | Yes |
549 | 3171 | 3171.0 | 85.14 | 85.1 | The nuclear factor NF-kappaB pathway in inflammation. | Toby Lawrence | Cold Spring Harb Perspect Biol | 2009 | 20457564 | No |
550 | 12662 | 3165.5 | 480.63 | 120.2 | APACHE II: a severity of disease classification system. | W A Knaus, E A Draper, D P Wagner, J E Zimmerman | Crit Care Med | 1985 | 3928249 | Yes |
551 | 6330 | 3165.0 | 133.18 | 66.6 | Toll-like receptor signalling. | Shizuo Akira, Kiyoshi Takeda | Nat Rev Immunol | 2004 | 15229469 | No |
552 | 9492 | 3164.0 | 267.8 | 89.3 | Detecting the number of clusters of individuals using the software STRUCTURE: a simulation study. | G Evanno, S Regnaut, J Goudet | Mol Ecol | 2005 | 15969739 | Yes |
553 | 3158 | 3158.0 | 78.1 | 78.1 | The transforming growth factor-beta family. | J Massagué | Annu Rev Cell Biol | 1990 | 2177343 | No |
554 | 6312 | 3156.0 | 207.37 | 103.7 | Measuring agreement in method comparison studies. | J M Bland, D G Altman | Stat Methods Med Res | 1999 | 10501650 | No |
555 | 3155 | 3155.0 | 96.55 | 96.5 | Expert committee recommendations regarding the prevention, assessment, and treatment of child and adolescent overweight and obesity: summary report. | Sarah E Barlow | Pediatrics | 2007 | 18055651 | Yes |
556 | 6306 | 3153.0 | 54.43 | 27.2 | The serial cultivation of human diploid cell strains. | L Hayflick, P S Moorhead | Exp Cell Res | 1961 | 13905658 | Yes |
557 | 3153 | 3153.0 | 78.43 | 78.4 | Cellular and molecular mechanisms of fibrosis. | T A Wynn | J Pathol | 2008 | 18161745 | No |
558 | 3148 | 3148.0 | 90.67 | 90.7 | Efficient methods to compute genomic predictions. | P M VanRaden | J Dairy Sci | 2008 | 18946147 | Yes |
559 | 22018 | 3145.4 | 816.58 | 116.7 | limma powers differential expression analyses for RNA-sequencing and microarray studies. | Matthew E Ritchie, Belinda Phipson, Di Wu, Yifang Hu, Charity W Law, Wei Shi, Gordon K Smyth | Nucleic Acids Res | 2015 | 25605792 | Yes |
560 | 6290 | 3145.0 | 102.11 | 51.1 | Pain mechanisms: a new theory. | R Melzack, P D Wall | Science | 1965 | 5320816 | No |
561 | 3139 | 3139.0 | 121.9 | 121.9 | Half a century of research on the Stroop effect: an integrative review. | C M MacLeod | Psychol Bull | 1991 | 2034749 | No |
562 | 3139 | 3139.0 | 26.9 | 26.9 | Gene action in the X-chromosome of the mouse (Mus musculus L.). | M F Lyon | Nature | 1961 | 13764598 | Yes |
563 | 6278 | 3139.0 | 268.73 | 134.4 | GenAlEx 6.5: genetic analysis in Excel. Population genetic software for teaching and research--an update. | Rod Peakall, Peter E Smouse | Bioinformatics | 2012 | 22820204 | Yes |
564 | 6276 | 3138.0 | 152.34 | 76.2 | In vitro selection of RNA molecules that bind specific ligands. | A D Ellington, J W Szostak | Nature | 1990 | 1697402 | Yes |
565 | 3138 | 3138.0 | 65.62 | 65.6 | Angiogenesis in health and disease. | Peter Carmeliet | Nat Med | 2003 | 12778163 | No |
566 | 3138 | 3138.0 | 0.0 | 0.0 | Diffusion-in-gel methods for immunological analysis. | O Ouchterlony | Prog Allergy | 1958 | 13578996 | Yes |
567 | 3137 | 3137.0 | 74.0 | 74.0 | WHAT IF: a molecular modeling and drug design program. | G Vriend | J Mol Graph | 1990 | 2268628 | Yes |
568 | 3129 | 3129.0 | 65.87 | 65.9 | Mechanisms of angiogenesis and arteriogenesis. | P Carmeliet | Nat Med | 2000 | 10742145 | No |
569 | 6256 | 3128.0 | 164.36 | 82.2 | The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. | Taro Kawai, Shizuo Akira | Nat Immunol | 2010 | 20404851 | No |
570 | 6241 | 3120.5 | 157.09 | 78.5 | Voxel-based morphometry--the methods. | J Ashburner, K J Friston | Neuroimage | 2000 | 10860804 | No |
571 | 9345 | 3115.0 | 194.17 | 64.7 | Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. | Benjamin P Lewis, Christopher B Burge, David P Bartel | Cell | 2005 | 15652477 | Yes |
572 | 3109 | 3109.0 | 125.16 | 125.2 | Adolescence-limited and life-course-persistent antisocial behavior: a developmental taxonomy. | T E Moffitt | Psychol Rev | 1993 | 8255953 | No |
573 | 3099 | 3099.0 | 75.98 | 76.0 | Recent advances with liposomes as pharmaceutical carriers. | Vladimir P Torchilin | Nat Rev Drug Discov | 2005 | 15688077 | No |
574 | 3098 | 3098.0 | 88.62 | 88.6 | Hepatocellular carcinoma. | Hashem B El-Serag | N Engl J Med | 2011 | 21992124 | No |
575 | 3097 | 3097.0 | 106.13 | 106.1 | The processing-speed theory of adult age differences in cognition. | T A Salthouse | Psychol Rev | 1996 | 8759042 | No |
576 | 9283 | 3094.3 | 311.95 | 104.0 | Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. | R M Palmer, A G Ferrige, S Moncada | Nature | 1987 | 3495737 | Yes |
577 | 6181 | 3090.5 | 136.4 | 68.2 | MicroRNA signatures in human cancers. | George A Calin, Carlo M Croce | Nat Rev Cancer | 2006 | 17060945 | No |
578 | 6180 | 3090.0 | 180.7 | 90.3 | mTOR signaling in growth control and disease. | Mathieu Laplante, David M Sabatini | Cell | 2012 | 22500797 | No |
579 | 6179 | 3089.5 | 108.75 | 54.4 | The language of covalent histone modifications. | B D Strahl, C D Allis | Nature | 2000 | 10638745 | Yes |
580 | 3089 | 3089.0 | 72.73 | 72.7 | Obesity as a medical problem. | P G Kopelman | Nature | 2000 | 10766250 | No |
581 | 24672 | 3084.0 | 532.79 | 66.6 | The Protein Data Bank. | H M Berman, J Westbrook, Z Feng, G Gilliland, T N Bhat, H Weissig, I N Shindyalov, P E Bourne | Nucleic Acids Res | 2000 | 10592235 | Yes |
582 | 3074 | 3074.0 | 57.23 | 57.2 | Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and lamm equation modeling. | P Schuck | Biophys J | 2000 | 10692345 | Yes |
583 | 3066 | 3066.0 | 83.36 | 83.4 | Rapid isolation of antigens from cells with a staphylococcal protein A-antibody adsorbent: parameters of the interaction of antibody-antigen complexes with protein A. | S W Kessler | J Immunol | 1975 | 1102604 | Yes |
584 | 3064 | 3064.0 | 103.23 | 103.2 | What is value in health care? | Michael E Porter | N Engl J Med | 2010 | 21142528 | Yes |
585 | 33696 | 3063.3 | 702.08 | 63.8 | Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. | Aravind Subramanian, Pablo Tamayo, Vamsi K Mootha, Sayan Mukherjee, Benjamin L Ebert, Michael A Gillette, Amanda Paulovich, Scott L Pomeroy, Todd R Golub, Eric S Lander, Jill P Mesirov | Proc Natl Acad Sci U S A | 2005 | 16199517 | Yes |
586 | 3063 | 3063.0 | 65.12 | 65.1 | TGFbeta in Cancer. | Joan Massagué | Cell | 2008 | 18662538 | No |
587 | 12218 | 3054.5 | 536.49 | 134.1 | IQ-TREE: a fast and effective stochastic algorithm for estimating maximum-likelihood phylogenies. | Lam-Tung Nguyen, Heiko A Schmidt, Arndt von Haeseler, Bui Quang Minh | Mol Biol Evol | 2015 | 25371430 | Yes |
588 | 9157 | 3052.3 | 172.57 | 57.5 | Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. | Ron Edgar, Michael Domrachev, Alex E Lash | Nucleic Acids Res | 2002 | 11752295 | Yes |
589 | 3046 | 3046.0 | 137.39 | 137.4 | The short-form McGill Pain Questionnaire. | Ronald Melzack | Pain | 1987 | 3670870 | Yes |
590 | 6087 | 3043.5 | 226.2 | 113.1 | The structure of negative emotional states: comparison of the Depression Anxiety Stress Scales (DASS) with the Beck Depression and Anxiety Inventories. | P F Lovibond, S H Lovibond | Behav Res Ther | 1995 | 7726811 | Yes |
591 | 6087 | 3043.5 | 0.0 | 0.0 | A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. | S Reitman, S Frankel | Am J Clin Pathol | 1957 | 13458125 | Yes |
592 | 3042 | 3042.0 | 70.5 | 70.5 | Cadherin cell adhesion receptors as a morphogenetic regulator. | M Takeichi | Science | 1991 | 2006419 | No |
593 | 3042 | 3042.0 | 48.34 | 48.3 | A Rapid Permethylation Of Glycolipid, And Polysaccharide Catalyzed By Methylsulfinyl Carbanion In Dimethyl Sulfoxide. | S Hakomori | J Biochem | 1964 | 14135466 | Yes |
594 | 3038 | 3038.0 | 102.73 | 102.7 | Measurement of pain. | E C Huskisson | Lancet | 1974 | 4139420 | Yes |
595 | 3037 | 3037.0 | 72.52 | 72.5 | The resurgence of platinum-based cancer chemotherapy. | Lloyd Kelland | Nat Rev Cancer | 2007 | 17625587 | No |
596 | 6059 | 3029.5 | 185.95 | 93.0 | Electrochemical photolysis of water at a semiconductor electrode. | A Fujishima, K Honda | Nature | 1972 | 12635268 | Yes |
597 | 6057 | 3028.5 | 143.51 | 71.8 | Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. | T C Chou, P Talalay | Adv Enzyme Regul | 1984 | 6382953 | Yes |
598 | 12077 | 3019.2 | 284.52 | 71.1 | Haploview: analysis and visualization of LD and haplotype maps. | J C Barrett, B Fry, J Maller, M J Daly | Bioinformatics | 2005 | 15297300 | Yes |
599 | 9030 | 3010.0 | 176.96 | 59.0 | Significance analysis of microarrays applied to the ionizing radiation response. | V G Tusher, R Tibshirani, G Chu | Proc Natl Acad Sci U S A | 2001 | 11309499 | Yes |
600 | 3008 | 3008.0 | 0.0 | 0.0 | A study of fixation for electron microscopy. | G E Palade | J Exp Med | 1952 | 14927794 | Yes |
601 | 3001 | 3001.0 | 126.24 | 126.2 | Statistics corner: A guide to appropriate use of correlation coefficient in medical research. | M M Mukaka | Malawi Med J | 2012 | 23638278 | Yes |
602 | 6001 | 3000.5 | 134.94 | 67.5 | Oxidants, oxidative stress and the biology of ageing. | T Finkel, N J Holbrook | Nature | 2000 | 11089981 | No |
603 | 8993 | 2997.7 | 206.17 | 68.7 | TopHat: discovering splice junctions with RNA-Seq. | Cole Trapnell, Lior Pachter, Steven L Salzberg | Bioinformatics | 2009 | 19289445 | Yes |
604 | 2990 | 2990.0 | 70.35 | 70.3 | MapChart: software for the graphical presentation of linkage maps and QTLs. | R E Voorrips | J Hered | 2002 | 12011185 | Yes |
605 | 2987 | 2987.0 | 90.63 | 90.6 | Estimation of metabolite concentrations from localized in vivo proton NMR spectra. | S W Provencher | Magn Reson Med | 1993 | 8139448 | Yes |
606 | 2985 | 2985.0 | 59.02 | 59.0 | Toll-like receptors and innate immunity. | R Medzhitov | Nat Rev Immunol | 2001 | 11905821 | No |
607 | 8953 | 2984.3 | 450.23 | 150.1 | Methods for dietary fiber, neutral detergent fiber, and nonstarch polysaccharides in relation to animal nutrition. | P J Van Soest, J B Robertson, B A Lewis | J Dairy Sci | 1991 | 1660498 | No |
608 | 2984 | 2984.0 | 0.0 | 0.0 | Catheter replacement of the needle in percutaneous arteriography; a new technique. | S I Seldinger | Acta Radiol (Stockh) | 1953 | 13057644 | Yes |
609 | 2981 | 2981.0 | 73.51 | 73.5 | Optimal two-stage designs for phase II clinical trials. | R Simon | Control Clin Trials | 1989 | 2702835 | Yes |
610 | 2979 | 2979.0 | 54.76 | 54.8 | RNA interference. | Gregory J Hannon | Nature | 2002 | 12110901 | No |
611 | 2975 | 2975.0 | 68.67 | 68.7 | Chemokines--chemotactic cytokines that mediate inflammation. | A D Luster | N Engl J Med | 1998 | 9459648 | No |
612 | 5947 | 2973.5 | 125.08 | 62.5 | Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. | D B Smith, K S Johnson | Gene | 1988 | 3047011 | Yes |
613 | 5947 | 2973.5 | 153.87 | 76.9 | Pattern recognition receptors and inflammation. | Osamu Takeuchi, Shizuo Akira | Cell | 2010 | 20303872 | No |
614 | 2973 | 2973.0 | 52.91 | 52.9 | The gel-filtration behaviour of proteins related to their molecular weights over a wide range. | P Andrews | Biochem J | 1965 | 5862401 | Yes |
615 | 8916 | 2972.0 | 289.95 | 96.6 | Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. | R A Deyo, D C Cherkin, M A Ciol | J Clin Epidemiol | 1992 | 1607900 | Yes |
616 | 5937 | 2968.5 | 125.23 | 62.6 | Emergence of scaling in random networks | A L Barabasi, R Albert | Science | 1999 | 10521342 | Yes |
617 | 2965 | 2965.0 | 94.35 | 94.3 | An empirical correction for absorption anisotropy. | R H Blessing | Acta Crystallogr A | 1995 | 7702794 | Yes |
618 | 2962 | 2962.0 | 91.32 | 91.3 | Matrix metalloproteinases and their inhibitors in connective tissue remodeling. | J F Woessner | FASEB J | 1991 | 1850705 | No |
619 | 2958 | 2958.0 | 66.54 | 66.5 | Calcium signaling. | David E Clapham | Cell | 2007 | 18083096 | No |
620 | 2956 | 2956.0 | 66.35 | 66.3 | Autophagy: process and function. | Noboru Mizushima | Genes Dev | 2007 | 18006683 | No |
621 | 2953 | 2953.0 | 103.27 | 103.3 | Measures of reliability in sports medicine and science. | W G Hopkins | Sports Med | 2000 | 10907753 | Yes |
622 | 8829 | 2943.0 | 242.02 | 80.7 | Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. | Y Gavrieli, Y Sherman, S A Ben-Sasson | J Cell Biol | 1992 | 1400587 | Yes |
623 | 8820 | 2940.0 | 203.68 | 67.9 | The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. | R C Lee, R L Feinbaum, V Ambros | Cell | 1993 | 8252621 | Yes |
624 | 5876 | 2938.0 | 184.59 | 92.3 | Tissue engineering. | R Langer, J P Vacanti | Science | 1993 | 8493529 | No |
625 | 5876 | 2938.0 | 122.83 | 61.4 | Inflammation and cancer: back to Virchow? | F Balkwill, A Mantovani | Lancet | 2001 | 11229684 | No |
626 | 11749 | 2937.2 | 344.54 | 86.1 | Naive Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy. | Qiong Wang, George M Garrity, James M Tiedje, James R Cole | Appl Environ Microbiol | 2007 | 17586664 | Yes |
627 | 5872 | 2936.0 | 231.15 | 115.6 | Assessment of outcome after severe brain damage. | B Jennett, M Bond | Lancet | 1975 | 46957 | Yes |
628 | 2936 | 2936.0 | 47.66 | 47.7 | A Rationale And Test For The Number Of Factors In Factor Analysis. | J L Horn | Psychometrika | 1965 | 14306381 | Yes |
629 | 2933 | 2933.0 | 107.93 | 107.9 | Role of nrf2 in oxidative stress and toxicity. | Qiang Ma | Annu Rev Pharmacol Toxicol | 2013 | 23294312 | No |
630 | 5859 | 2929.5 | 154.32 | 77.2 | Unified segmentation. | John Ashburner, Karl J Friston | Neuroimage | 2005 | 15955494 | Yes |
631 | 2920 | 2920.0 | 43.87 | 43.9 | Towards a network theory of the immune system. | N K Jerne | Ann Immunol (Paris) | 1974 | 4142565 | No |
632 | 2918 | 2918.0 | 67.73 | 67.7 | Modularity and community structure in networks. | M E J Newman | Proc Natl Acad Sci U S A | 2006 | 16723398 | Yes |
633 | 2918 | 2918.0 | 0.0 | 0.0 | The genetical structure of populations. | S Wright | Ann Eugen | 1951 | 24540312 | Yes |
634 | 2910 | 2910.0 | 68.77 | 68.8 | Structure and function of telomeres. | E H Blackburn | Nature | 1991 | 1708110 | No |
635 | 2907 | 2907.0 | 29.35 | 29.4 | Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism. | P Mitchell | Nature | 1961 | 13771349 | Yes |
636 | 8698 | 2899.3 | 0.0 | 0.0 | The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. | R J Havel, H A Eder, J H Bragdon | J Clin Invest | 1955 | 13252080 | Yes |
637 | 2898 | 2898.0 | 70.66 | 70.7 | Phase separation of integral membrane proteins in Triton X-114 solution. | C Bordier | J Biol Chem | 1981 | 6257680 | Yes |
638 | 5793 | 2896.5 | 161.85 | 80.9 | Inositol trisphosphate, a novel second messenger in cellular signal transduction. | M J Berridge, R F Irvine | Nature | 1984 | 6095092 | No |
639 | 2894 | 2894.0 | 61.91 | 61.9 | Inflammatory bowel disease. | Daniel K Podolsky | N Engl J Med | 2002 | 12167685 | No |
640 | 5787 | 2893.5 | 178.18 | 89.1 | The fluid mosaic model of the structure of cell membranes. | S J Singer, G L Nicolson | Science | 1972 | 4333397 | Yes |
641 | 2888 | 2888.0 | 59.82 | 59.8 | Principles of CDK regulation. | D O Morgan | Nature | 1995 | 7877684 | No |
642 | 5772 | 2886.0 | 126.69 | 63.3 | Oncomirs - microRNAs with a role in cancer. | Aurora Esquela-Kerscher, Frank J Slack | Nat Rev Cancer | 2006 | 16557279 | No |
643 | 2881 | 2881.0 | 154.06 | 154.1 | Hepatocellular Carcinoma. | Augusto Villanueva | N Engl J Med | 2019 | 30970190 | No |
644 | 2877 | 2877.0 | 86.01 | 86.0 | Implications of normal brain development for the pathogenesis of schizophrenia. | D R Weinberger | Arch Gen Psychiatry | 1987 | 3606332 | Yes |
645 | 2875 | 2875.0 | 55.99 | 56.0 | Interleukin-12 and the regulation of innate resistance and adaptive immunity. | Giorgio Trinchieri | Nat Rev Immunol | 2003 | 12563297 | No |
646 | 5744 | 2872.0 | 272.99 | 136.5 | Stress, social support, and the buffering hypothesis. | S Cohen, T A Wills | Psychol Bull | 1985 | 3901065 | No |
647 | 2872 | 2872.0 | 72.39 | 72.4 | Analysis of gene diversity in subdivided populations. | M Nei | Proc Natl Acad Sci U S A | 1973 | 4519626 | Yes |
648 | 2872 | 2872.0 | 50.46 | 50.5 | A Generalized Wilcoxon Test For Comparing Arbitrarily Singly-Censored Samples. | E A Gehan | Biometrika | 1965 | 14341275 | Yes |
649 | 2869 | 2869.0 | 56.36 | 56.4 | A gene complex controlling segmentation in Drosophila. | E B Lewis | Nature | 1978 | 103000 | Yes |
650 | 2869 | 2869.0 | 63.94 | 63.9 | Salt and drought stress signal transduction in plants. | Jian-Kang Zhu | Annu Rev Plant Biol | 2002 | 12221975 | No |
651 | 2864 | 2864.0 | 50.79 | 50.8 | One-step gene disruption in yeast. | R J Rothstein | Methods Enzymol | 1983 | 6310324 | Yes |
652 | 2864 | 2864.0 | 56.46 | 56.5 | Papillomaviruses and cancer: from basic studies to clinical application. | Harald zur Hausen | Nat Rev Cancer | 2002 | 12044010 | No |
653 | 2862 | 2862.0 | 0.0 | 0.0 | Notes on sugar determination. | M Smogyi | J Biol Chem | 1952 | 14938350 | Yes |
654 | 2862 | 2862.0 | 61.17 | 61.2 | Nuclear factor-kappaB in cancer development and progression. | Michael Karin | Nature | 2006 | 16724054 | No |
655 | 2861 | 2861.0 | 0.0 | 0.0 | Phosphorus compounds in animal tissues; extraction and estimation of desoxypentose nucleic acid and of pentose nucleic acid. | W C Schneider | J Biol Chem | 1945 | 21005736 | Yes |
656 | 2860 | 2860.0 | 95.53 | 95.5 | Role of oxidative stress in development of complications in diabetes. | J W Baynes | Diabetes | 1991 | 2010041 | No |
657 | 2860 | 2860.0 | 52.38 | 52.4 | Genome maintenance mechanisms for preventing cancer. | J H Hoeijmakers | Nature | 2001 | 11357144 | No |
658 | 8577 | 2859.0 | 209.19 | 69.7 | Canonical sampling through velocity rescaling. | Giovanni Bussi, Davide Donadio, Michele Parrinello | J Chem Phys | 2007 | 17212484 | Yes |
659 | 8570 | 2856.7 | 368.9 | 123.0 | Detection of postnatal depression. Development of the 10-item Edinburgh Postnatal Depression Scale. | J L Cox, J M Holden, R Sagovsky | Br J Psychiatry | 1987 | 3651732 | Yes |
660 | 5709 | 2854.5 | 248.39 | 124.2 | Revised methods for the Salmonella mutagenicity test. | D M Maron, B N Ames | Mutat Res | 1983 | 6341825 | Yes |
661 | 2852 | 2852.0 | 67.16 | 67.2 | T cell exhaustion. | E John Wherry | Nat Immunol | 2011 | 21739672 | No |
662 | 8544 | 2848.0 | 246.81 | 82.3 | Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane. | G Fairbanks, T L Steck, D F Wallach | Biochemistry | 1971 | 4326772 | Yes |
663 | 8541 | 2847.0 | 250.31 | 83.4 | FastTree 2--approximately maximum-likelihood trees for large alignments. | Morgan N Price, Paramvir S Dehal, Adam P Arkin | PLoS One | 2010 | 20224823 | Yes |
664 | 2836 | 2836.0 | 96.76 | 96.8 | Some studies of the protein-binding of steroids and their application to the routine micro and ultramicro measurement of various steroids in body fluids by competitive protein-binding radioassay. | B E Murphy | J Clin Endocrinol Metab | 1967 | 4291524 | Yes |
665 | 2835 | 2835.0 | 78.61 | 78.6 | Separation of leukocytes from blood and bone marrow. Introduction. | A Böyum | Scand J Clin Lab Invest Suppl | 1968 | 5707208 | Yes |
666 | 2835 | 2835.0 | 0.0 | 0.0 | A study of the adrenotropic receptors. | R P Ahlquist | Am J Physiol | 1948 | 18882199 | Yes |
667 | 2832 | 2832.0 | 85.72 | 85.7 | Primate models of movement disorders of basal ganglia origin. | M R DeLong | Trends Neurosci | 1990 | 1695404 | No |
668 | 2822 | 2822.0 | 53.83 | 53.8 | Elastic properties of lipid bilayers: theory and possible experiments. | W Helfrich | Z Naturforsch C | 1973 | 4273690 | Yes |
669 | 5643 | 2821.5 | 174.02 | 87.0 | Computed tomography--an increasing source of radiation exposure. | David J Brenner, Eric J Hall | N Engl J Med | 2007 | 18046031 | No |
670 | 5642 | 2821.0 | 158.88 | 79.4 | Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain. | J Glowinski, L L Iversen | J Neurochem | 1966 | 5950056 | Yes |
671 | 11282 | 2820.5 | 1275.86 | 319.0 | Cancer Statistics, 2021. | Rebecca L Siegel, Kimberly D Miller, Hannah E Fuchs, Ahmedin Jemal | CA Cancer J Clin | 2021 | 33433946 | Yes |
672 | 2820 | 2820.0 | 78.97 | 79.0 | Parkinson's disease: clinical features and diagnosis. | J Jankovic | J Neurol Neurosurg Psychiatry | 2008 | 18344392 | No |
673 | 2817 | 2817.0 | 121.75 | 121.8 | Colorimetric assay of catalase. | A K Sinha | Anal Biochem | 1972 | 4556490 | Yes |
674 | 2814 | 2814.0 | 126.66 | 126.7 | Detecting alcoholism. The CAGE questionnaire. | J A Ewing | JAMA | 1984 | 6471323 | Yes |
675 | 2814 | 2814.0 | 70.41 | 70.4 | Dietary pattern analysis: a new direction in nutritional epidemiology. | Frank B Hu | Curr Opin Lipidol | 2002 | 11790957 | No |
676 | 2812 | 2812.0 | 47.73 | 47.7 | Mechanisms underlying ubiquitination. | C M Pickart | Annu Rev Biochem | 2001 | 11395416 | No |
677 | 5620 | 2810.0 | 113.23 | 56.6 | Establishment in culture of pluripotential cells from mouse embryos. | M J Evans, M H Kaufman | Nature | 1981 | 7242681 | Yes |
678 | 8428 | 2809.3 | 283.07 | 94.4 | Effect of the damping function in dispersion corrected density functional theory. | Stefan Grimme, Stephan Ehrlich, Lars Goerigk | J Comput Chem | 2011 | 21370243 | Yes |
679 | 5612 | 2806.0 | 193.14 | 96.6 | A method of comparing the areas under receiver operating characteristic curves derived from the same cases. | J A Hanley, B J McNeil | Radiology | 1983 | 6878708 | Yes |
680 | 5606 | 2803.0 | 135.13 | 67.6 | Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. | S Marklund, G Marklund | Eur J Biochem | 1974 | 4215654 | Yes |
681 | 2802 | 2802.0 | 70.5 | 70.5 | The genetic legacy of the Quaternary ice ages. | G Hewitt | Nature | 2000 | 10879524 | No |
682 | 8404 | 2801.3 | 190.44 | 63.5 | Pathogen recognition and innate immunity. | Shizuo Akira, Satoshi Uematsu, Osamu Takeuchi | Cell | 2006 | 16497588 | No |
683 | 2801 | 2801.0 | 80.72 | 80.7 | The unfolded protein response: controlling cell fate decisions under ER stress and beyond. | Claudio Hetz | Nat Rev Mol Cell Biol | 2012 | 22251901 | No |
684 | 5601 | 2800.5 | 152.34 | 76.2 | The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers. | J Vieira, J Messing | Gene | 1982 | 6295879 | Yes |
685 | 5598 | 2799.0 | 183.92 | 92.0 | Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. | J Sedlak, R H Lindsay | Anal Biochem | 1968 | 4973948 | Yes |
686 | 5591 | 2795.5 | 110.2 | 55.1 | Innate immune recognition. | Charles A Janeway, Ruslan Medzhitov | Annu Rev Immunol | 2002 | 11861602 | No |
687 | 2792 | 2792.0 | 89.54 | 89.5 | Stereotaxic mapping of the monoamine pathways in the rat brain. | U Ungerstedt | Acta Physiol Scand Suppl | 1971 | 4109331 | Yes |
688 | 2791 | 2791.0 | 70.12 | 70.1 | Models for the specific adhesion of cells to cells. | G I Bell | Science | 1978 | 347575 | No |
689 | 5580 | 2790.0 | 77.82 | 38.9 | A method for determining the sedimentation behavior of enzymes: application to protein mixtures. | R G Martin, B N Ames | J Biol Chem | 1961 | 13767412 | Yes |
690 | 5578 | 2789.0 | 126.34 | 63.2 | Caspases: enemies within. | N A Thornberry, Y Lazebnik | Science | 1998 | 9721091 | No |
691 | 11135 | 2783.8 | 295.38 | 73.8 | Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. | P W Rigby, M Dieckmann, C Rhodes, P Berg | J Mol Biol | 1977 | 881736 | Yes |
692 | 5567 | 2783.5 | 200.91 | 100.5 | Longitudinal data analysis for discrete and continuous outcomes. | S L Zeger, K Y Liang | Biometrics | 1986 | 3719049 | Yes |
693 | 2783 | 2783.0 | 83.57 | 83.6 | SF-36 health survey update. | J E Ware | Spine (Phila Pa 1976) | 2000 | 11124729 | No |
694 | 2780 | 2780.0 | 65.16 | 65.2 | Molecular chaperones in cellular protein folding. | F U Hartl | Nature | 1996 | 8637592 | No |
695 | 5560 | 2780.0 | 187.03 | 93.5 | Extracellular vesicles: exosomes, microvesicles, and friends. | Graça Raposo, Willem Stoorvogel | J Cell Biol | 2013 | 23420871 | No |
696 | 2779 | 2779.0 | 112.54 | 112.5 | Microplastics in the marine environment. | Anthony L Andrady | Mar Pollut Bull | 2011 | 21742351 | No |
697 | 2777 | 2777.0 | 108.94 | 108.9 | A simple technique for demonstrating centromeric heterochromatin. | A T Sumner | Exp Cell Res | 1972 | 4117921 | Yes |
698 | 5547 | 2773.5 | 152.93 | 76.5 | Adherence to medication. | Lars Osterberg, Terrence Blaschke | N Engl J Med | 2005 | 16079372 | No |
699 | 11089 | 2772.2 | 334.87 | 83.7 | Cancer statistics, 2010. | Ahmedin Jemal, Rebecca Siegel, Jiaquan Xu, Elizabeth Ward | CA Cancer J Clin | 2010 | 20610543 | Yes |
700 | 2770 | 2770.0 | 0.0 | 0.0 | Efficient trace-labelling of proteins with iodine. | A S McFARLANE | Nature | 1958 | 13566175 | Yes |
701 | 5537 | 2768.5 | 130.68 | 65.3 | Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. | F W Studier, B A Moffatt | J Mol Biol | 1986 | 3537305 | Yes |
702 | 5527 | 2763.5 | 161.06 | 80.5 | Long-range corrected hybrid density functionals with damped atom-atom dispersion corrections. | Jeng-Da Chai, Martin Head-Gordon | Phys Chem Chem Phys | 2008 | 18989472 | Yes |
703 | 5523 | 2761.5 | 127.77 | 63.9 | Autophagy in the pathogenesis of disease. | Beth Levine, Guido Kroemer | Cell | 2008 | 18191218 | No |
704 | 5517 | 2758.5 | 133.86 | 66.9 | Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. | D Hanahan, J Folkman | Cell | 1996 | 8756718 | No |
705 | 2751 | 2751.0 | 59.17 | 59.2 | Bone resorption by osteoclasts. | S L Teitelbaum | Science | 2000 | 10968780 | No |
706 | 2749 | 2749.0 | 70.62 | 70.6 | Predictive reward signal of dopamine neurons. | W Schultz | J Neurophysiol | 1998 | 9658025 | No |
707 | 5498 | 2749.0 | 309.55 | 154.8 | A modified uronic acid carbazole reaction. | T Bitter, H M Muir | Anal Biochem | 1962 | 13971270 | Yes |
708 | 2745 | 2745.0 | 86.5 | 86.5 | Social cognitive theory: an agentic perspective. | A Bandura | Annu Rev Psychol | 2001 | 11148297 | Yes |
709 | 2745 | 2745.0 | 0.0 | 0.0 | Quantitative estimation of sialic acids. II. A colorimetric resorcinol-hydrochloric acid method. | L Svennerholm | Biochim Biophys Acta | 1957 | 13436486 | Yes |
710 | 2741 | 2741.0 | 65.96 | 66.0 | Cell death during development of the nervous system. | R W Oppenheim | Annu Rev Neurosci | 1991 | 2031577 | No |
711 | 2741 | 2741.0 | 72.55 | 72.5 | The magical number 4 in short-term memory: a reconsideration of mental storage capacity. | N Cowan | Behav Brain Sci | 2001 | 11515286 | Yes |
712 | 2740 | 2740.0 | 61.72 | 61.7 | Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. | S A Bustin | J Mol Endocrinol | 2000 | 11013345 | No |
713 | 2735 | 2735.0 | 52.98 | 53.0 | The danger model: a renewed sense of self. | Polly Matzinger | Science | 2002 | 11951032 | Yes |
714 | 5469 | 2734.5 | 167.08 | 83.5 | Glutathione. | A Meister, M E Anderson | Annu Rev Biochem | 1983 | 6137189 | No |
715 | 5451 | 2725.5 | 107.67 | 53.8 | High-efficiency transformation of mammalian cells by plasmid DNA. | C Chen, H Okayama | Mol Cell Biol | 1987 | 3670292 | Yes |
716 | 5430 | 2715.0 | 185.71 | 92.9 | The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions. | S H Downs, N Black | J Epidemiol Community Health | 1998 | 9764259 | Yes |
717 | 8144 | 2714.7 | 175.05 | 58.4 | Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. | C M Gorman, L F Moffat, B H Howard | Mol Cell Biol | 1982 | 6960240 | Yes |
718 | 16277 | 2712.8 | 362.71 | 60.5 | Phaser crystallographic software. | Airlie J McCoy, Ralf W Grosse-Kunstleve, Paul D Adams, Martyn D Winn, Laurent C Storoni, Randy J Read | J Appl Crystallogr | 2007 | 19461840 | Yes |
719 | 2711 | 2711.0 | 62.69 | 62.7 | Memory--a century of consolidation. | J L McGaugh | Science | 2000 | 10634773 | No |
720 | 2710 | 2710.0 | 61.05 | 61.0 | Cell adhesion: the molecular basis of tissue architecture and morphogenesis. | B M Gumbiner | Cell | 1996 | 8608588 | No |
721 | 2707 | 2707.0 | 84.95 | 85.0 | A rating instrument for anxiety disorders. | W W Zung | Psychosomatics | 1971 | 5172928 | Yes |
722 | 2702 | 2702.0 | 65.19 | 65.2 | Molecular basis of bacterial outer membrane permeability revisited. | Hiroshi Nikaido | Microbiol Mol Biol Rev | 2003 | 14665678 | No |
723 | 2701 | 2701.0 | 105.0 | 105.0 | Central sensitization: implications for the diagnosis and treatment of pain. | Clifford J Woolf | Pain | 2011 | 20961685 | No |
724 | 2700 | 2700.0 | 60.57 | 60.6 | Prostaglandins and leukotrienes: advances in eicosanoid biology. | C D Funk | Science | 2001 | 11729303 | No |
725 | 10795 | 2698.8 | 317.38 | 79.3 | Establishing a standard definition for child overweight and obesity worldwide: international survey. | T J Cole, M C Bellizzi, K M Flegal, W H Dietz | BMJ | 2000 | 10797032 | Yes |
726 | 5396 | 2698.0 | 158.62 | 79.3 | The Social Readjustment Rating Scale. | T H Holmes, R H Rahe | J Psychosom Res | 1967 | 6059863 | Yes |
727 | 2694 | 2694.0 | 82.88 | 82.9 | The free-energy principle: a unified brain theory? | Karl Friston | Nat Rev Neurosci | 2010 | 20068583 | No |
728 | 2690 | 2690.0 | 57.81 | 57.8 | On the number of segregating sites in genetical models without recombination. | G A Watterson | Theor Popul Biol | 1975 | 1145509 | Yes |
729 | 2690 | 2690.0 | 23.54 | 23.5 | Satellite cell of skeletal muscle fibers. | A Mauro | J Biophys Biochem Cytol | 1961 | 13768451 | Yes |
730 | 2687 | 2687.0 | 135.43 | 135.4 | Conservation of resources. A new attempt at conceptualizing stress. | S E Hobfoll | Am Psychol | 1989 | 2648906 | No |
731 | 8060 | 2686.7 | 199.07 | 66.4 | MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment. | Sudhir Kumar, Koichiro Tamura, Masatoshi Nei | Brief Bioinform | 2004 | 15260895 | Yes |
732 | 5370 | 2685.0 | 165.21 | 82.6 | Rapid isolation of high molecular weight plant DNA. | M G Murray, W F Thompson | Nucleic Acids Res | 1980 | 7433111 | Yes |
733 | 10737 | 2684.2 | 227.33 | 56.8 | Cluster analysis and display of genome-wide expression patterns. | M B Eisen, P T Spellman, P O Brown, D Botstein | Proc Natl Acad Sci U S A | 1998 | 9843981 | Yes |
734 | 2678 | 2678.0 | 61.22 | 61.2 | Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface. | G P Smith | Science | 1985 | 4001944 | Yes |
735 | 2674 | 2674.0 | 51.38 | 51.4 | Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. | Shimon Sakaguchi | Annu Rev Immunol | 2004 | 15032588 | No |
736 | 2666 | 2666.0 | 59.79 | 59.8 | Vascular endothelial growth factor: basic science and clinical progress. | Napoleone Ferrara | Endocr Rev | 2004 | 15294883 | No |
737 | 5330 | 2665.0 | 0.0 | 0.0 | Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid. | J D Watson, F H Crick | Nature | 1953 | 13054692 | Yes |
738 | 2662 | 2662.0 | 91.15 | 91.2 | A computational approach to edge detection. | J Canny | IEEE Trans Pattern Anal Mach Intell | 1986 | 21869365 | Yes |
739 | 2662 | 2662.0 | 99.32 | 99.3 | The biology and function of fibroblasts in cancer. | Raghu Kalluri | Nat Rev Cancer | 2016 | 27550820 | No |
740 | 7984 | 2661.3 | 208.51 | 69.5 | Regularization Paths for Generalized Linear Models via Coordinate Descent. | Jerome Friedman, Trevor Hastie, Rob Tibshirani | J Stat Softw | 2010 | 20808728 | Yes |
741 | 2660 | 2660.0 | 61.34 | 61.3 | Protein purification by affinity chromatography. Derivatizations of agarose and polyacrylamide beads. | P Cuatrecasas | J Biol Chem | 1970 | 5432796 | Yes |
742 | 2653 | 2653.0 | 75.81 | 75.8 | Stress, adaptation, and disease. Allostasis and allostatic load. | B S McEwen | Ann N Y Acad Sci | 1998 | 9629234 | No |
743 | 5299 | 2649.5 | 164.1 | 82.0 | Accurate and simple analytic representation of the electron-gas correlation energy. | J P Perdew, Y Wang | Phys Rev B Condens Matter | 1992 | 10001404 | Yes |
744 | 5286 | 2643.0 | 210.44 | 105.2 | A feature-integration theory of attention. | A M Treisman, G Gelade | Cogn Psychol | 1980 | 7351125 | Yes |
745 | 2643 | 2643.0 | 107.04 | 107.0 | Qualitative research. Introducing focus groups. | J Kitzinger | BMJ | 1995 | 7633241 | Yes |
746 | 2642 | 2642.0 | 82.11 | 82.1 | What are the functional consequences of neurocognitive deficits in schizophrenia? | M F Green | Am J Psychiatry | 1996 | 8610818 | No |
747 | 5269 | 2634.5 | 107.97 | 54.0 | MicroRNAs: small RNAs with a big role in gene regulation. | Lin He, Gregory J Hannon | Nat Rev Genet | 2004 | 15211354 | No |
748 | 5255 | 2627.5 | 102.12 | 51.1 | Untangling the ErbB signalling network. | Y Yarden, M X Sliwkowski | Nat Rev Mol Cell Biol | 2001 | 11252954 | No |
749 | 5255 | 2627.5 | 106.04 | 53.0 | Periodontal Disease In Pregnancy. Ii. Correlation Between Oral Hygiene And Periodontal Condtion. | J Silness, H Loe | Acta Odontol Scand | 1964 | 14158464 | Yes |
750 | 2625 | 2625.0 | 65.4 | 65.4 | The nerve growth factor 35 years later. | R Levi-Montalcini | Science | 1987 | 3306916 | No |
751 | 2622 | 2622.0 | 105.9 | 105.9 | The biology of oxygen radicals. | I Fridovich | Science | 1978 | 210504 | Yes |
752 | 5242 | 2621.0 | 137.25 | 68.6 | Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. | L A Greene, A S Tischler | Proc Natl Acad Sci U S A | 1976 | 1065897 | Yes |
753 | 2619 | 2619.0 | 72.99 | 73.0 | Two-sided confidence intervals for the single proportion: comparison of seven methods. | R G Newcombe | Stat Med | 1998 | 9595616 | Yes |
754 | 2619 | 2619.0 | 81.16 | 81.2 | The role of positive emotions in positive psychology. The broaden-and-build theory of positive emotions. | B L Fredrickson | Am Psychol | 2001 | 11315248 | Yes |
755 | 10476 | 2619.0 | 538.34 | 134.6 | fastp: an ultra-fast all-in-one FASTQ preprocessor. | Shifu Chen, Yanqing Zhou, Yaru Chen, Jia Gu | Bioinformatics | 2018 | 30423086 | Yes |
756 | 2618 | 2618.0 | 72.79 | 72.8 | Human gastric carcinogenesis: a multistep and multifactorial process--First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. | P Correa | Cancer Res | 1992 | 1458460 | No |
757 | 2618 | 2618.0 | 127.85 | 127.8 | The antibiotic resistance crisis: part 1: causes and threats. | C Lee Ventola | P T | 2015 | 25859123 | Yes |
758 | 2614 | 2614.0 | 122.59 | 122.6 | The membrane actions of anesthetics and tranquilizers. | P Seeman | Pharmacol Rev | 1972 | 4565956 | No |
759 | 5223 | 2611.5 | 0.0 | 0.0 | Some quantitative uses of drug antagonists. | O Arunlakshana, H O Schild | Br J Pharmacol Chemother | 1959 | 13651579 | Yes |
760 | 7831 | 2610.3 | 225.25 | 75.1 | GSVA: gene set variation analysis for microarray and RNA-seq data. | Sonja Hänzelmann, Robert Castelo, Justin Guinney | BMC Bioinformatics | 2013 | 23323831 | Yes |
761 | 5220 | 2610.0 | 117.11 | 58.6 | Signal transduction by receptors with tyrosine kinase activity. | A Ullrich, J Schlessinger | Cell | 1990 | 2158859 | No |
762 | 5215 | 2607.5 | 128.43 | 64.2 | Reactive oxygen species: metabolism, oxidative stress, and signal transduction. | Klaus Apel, Heribert Hirt | Annu Rev Plant Biol | 2004 | 15377225 | No |
763 | 5213 | 2606.5 | 180.5 | 90.2 | A simple, rapid, and sensitive DNA assay procedure. | C Labarca, K Paigen | Anal Biochem | 1980 | 6158890 | Yes |
764 | 2606 | 2606.0 | 50.81 | 50.8 | Tumour-educated macrophages promote tumour progression and metastasis. | Jeffrey W Pollard | Nat Rev Cancer | 2004 | 14708027 | No |
765 | 10411 | 2602.8 | 1851.74 | 462.9 | Cancer statistics, 2022. | Rebecca L Siegel, Kimberly D Miller, Hannah E Fuchs, Ahmedin Jemal | CA Cancer J Clin | 2022 | 35020204 | Yes |
766 | 2601 | 2601.0 | 52.93 | 52.9 | Telomere measurement by quantitative PCR. | Richard M Cawthon | Nucleic Acids Res | 2002 | 12000852 | Yes |
767 | 2601 | 2601.0 | 56.52 | 56.5 | Epigenetics in cancer. | Manel Esteller | N Engl J Med | 2008 | 18337604 | No |
768 | 5197 | 2598.5 | 73.07 | 36.5 | A general method applicable to the search for similarities in the amino acid sequence of two proteins. | S B Needleman, C D Wunsch | J Mol Biol | 1970 | 5420325 | Yes |
769 | 2596 | 2596.0 | 71.55 | 71.5 | Physiology and neurobiology of stress and adaptation: central role of the brain. | Bruce S McEwen | Physiol Rev | 2007 | 17615391 | No |
770 | 2588 | 2588.0 | 53.72 | 53.7 | Evolving concepts of rheumatoid arthritis. | Gary S Firestein | Nature | 2003 | 12748655 | No |
771 | 2587 | 2587.0 | 61.56 | 61.6 | Cancer nanotechnology: opportunities and challenges. | Mauro Ferrari | Nat Rev Cancer | 2005 | 15738981 | No |
772 | 2585 | 2585.0 | 55.29 | 55.3 | G1 phase progression: cycling on cue. | C J Sherr | Cell | 1994 | 7954821 | No |
773 | 2585 | 2585.0 | 73.13 | 73.1 | Formation and Structure of Self-Assembled Monolayers. | Abraham Ulman | Chem Rev | 1996 | 11848802 | Yes |
774 | 5170 | 2585.0 | 160.61 | 80.3 | Microenvironmental regulation of tumor progression and metastasis. | Daniela F Quail, Johanna A Joyce | Nat Med | 2013 | 24202395 | No |
775 | 5162 | 2581.0 | 167.64 | 83.8 | The neural basis of drug craving: an incentive-sensitization theory of addiction. | T E Robinson, K C Berridge | Brain Res Brain Res Rev | 1993 | 8401595 | No |
776 | 2580 | 2580.0 | 80.73 | 80.7 | Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. | B Samuelsson | Science | 1983 | 6301011 | Yes |
777 | 2578 | 2578.0 | 0.0 | 0.0 | The Estimation Of Pepsin, Trypsin, Papain, And Cathepsin With Hemoglobin. | M L Anson | J Gen Physiol | 1938 | 19873094 | Yes |
778 | 5151 | 2575.5 | 160.38 | 80.2 | The L-arginine-nitric oxide pathway. | S Moncada, A Higgs | N Engl J Med | 1993 | 7504210 | No |
779 | 2573 | 2573.0 | 68.66 | 68.7 | Dominant forces in protein folding. | K A Dill | Biochemistry | 1990 | 2207096 | No |
780 | 2572 | 2572.0 | 73.33 | 73.3 | Delayed neuronal death in the gerbil hippocampus following ischemia. | T Kirino | Brain Res | 1982 | 7093691 | Yes |
781 | 2567 | 2567.0 | 61.7 | 61.7 | Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. | E C Butcher | Cell | 1991 | 1760836 | No |
782 | 2565 | 2565.0 | 36.16 | 36.2 | The catecholamine hypothesis of affective disorders: a review of supporting evidence. | J J Schildkraut | Am J Psychiatry | 1965 | 5319766 | No |
783 | 2565 | 2565.0 | 83.54 | 83.5 | Gctf: Real-time CTF determination and correction. | Kai Zhang | J Struct Biol | 2016 | 26592709 | Yes |
784 | 2561 | 2561.0 | 75.31 | 75.3 | Evaluating the quality of medical care. | A Donabedian | Milbank Mem Fund Q | 1966 | 5338568 | No |
785 | 2558 | 2558.0 | 0.0 | 0.0 | The hydrolysis of rabbit y-globulin and antibodies with crystalline papain. | R R Porter | Biochem J | 1959 | 14434282 | Yes |
786 | 5102 | 2551.0 | 224.65 | 112.3 | Clinical significance: a statistical approach to defining meaningful change in psychotherapy research. | N S Jacobson, P Truax | J Consult Clin Psychol | 1991 | 2002127 | Yes |
787 | 2548 | 2548.0 | 54.95 | 55.0 | Angiogenesis in life, disease and medicine. | Peter Carmeliet | Nature | 2005 | 16355210 | No |
788 | 2546 | 2546.0 | 62.12 | 62.1 | A mechanism for cognitive dynamics: neuronal communication through neuronal coherence. | Pascal Fries | Trends Cogn Sci | 2005 | 16150631 | No |
789 | 2544 | 2544.0 | 0.0 | 0.0 | Zone electrophoresis in starch gels: group variations in the serum proteins of normal human adults. | O Smithies | Biochem J | 1955 | 13276348 | Yes |
790 | 7615 | 2538.3 | 199.52 | 66.5 | Immunity, inflammation, and cancer. | Sergei I Grivennikov, Florian R Greten, Michael Karin | Cell | 2010 | 20303878 | No |
791 | 2536 | 2536.0 | 55.64 | 55.6 | The distribution of secondary growths in cancer of the breast. 1889. | S Paget | Cancer Metastasis Rev | 1989 | 2673568 | No |
792 | 2534 | 2534.0 | 73.23 | 73.2 | Perceived exertion as an indicator of somatic stress. | G Borg | Scand J Rehabil Med | 1970 | 5523831 | Yes |
793 | 5068 | 2534.0 | 116.34 | 58.2 | Myeloid-derived suppressor cells as regulators of the immune system. | Dmitry I Gabrilovich, Srinivas Nagaraj | Nat Rev Immunol | 2009 | 19197294 | No |
794 | 5067 | 2533.5 | 276.0 | 138.0 | A diagnostic interview: the schedule for affective disorders and schizophrenia. | J Endicott, R L Spitzer | Arch Gen Psychiatry | 1978 | 678037 | Yes |
795 | 2533 | 2533.0 | 51.06 | 51.1 | Universal control mechanism regulating onset of M-phase. | P Nurse | Nature | 1990 | 2138713 | No |
796 | 5058 | 2529.0 | 130.85 | 65.4 | UniFrac: a new phylogenetic method for comparing microbial communities. | Catherine Lozupone, Rob Knight | Appl Environ Microbiol | 2005 | 16332807 | Yes |
797 | 7583 | 2527.7 | 188.2 | 62.7 | RNA-Seq: a revolutionary tool for transcriptomics. | Zhong Wang, Mark Gerstein, Michael Snyder | Nat Rev Genet | 2009 | 19015660 | No |
798 | 2525 | 2525.0 | 122.53 | 122.5 | The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes. | S Boyden | J Exp Med | 1962 | 13872176 | Yes |
799 | 7554 | 2518.0 | 204.47 | 68.2 | Quantum mechanical continuum solvation models. | Jacopo Tomasi, Benedetta Mennucci, Roberto Cammi | Chem Rev | 2005 | 16092826 | Yes |
800 | 7543 | 2514.3 | 195.07 | 65.0 | Cortical surface-based analysis. I. Segmentation and surface reconstruction. | A M Dale, B Fischl, M I Sereno | Neuroimage | 1999 | 9931268 | Yes |
801 | 2513 | 2513.0 | 77.22 | 77.2 | Secretory products of macrophages. | C F Nathan | J Clin Invest | 1987 | 3543052 | No |
802 | 2508 | 2508.0 | 62.06 | 62.1 | Immunological and inflammatory functions of the interleukin-1 family. | Charles A Dinarello | Annu Rev Immunol | 2009 | 19302047 | No |
803 | 5015 | 2507.5 | 100.32 | 50.2 | Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. | D Bonnet, J E Dick | Nat Med | 1997 | 9212098 | Yes |
804 | 2506 | 2506.0 | 44.91 | 44.9 | Wnt signaling and cancer. | P Polakis | Genes Dev | 2000 | 10921899 | No |
805 | 2505 | 2505.0 | 62.81 | 62.8 | Inferring the historical patterns of biological evolution. | M Pagel | Nature | 1999 | 10553904 | Yes |
806 | 10019 | 2504.8 | 399.35 | 99.8 | Cancer statistics, 2014. | Rebecca Siegel, Jiemin Ma, Zhaohui Zou, Ahmedin Jemal | CA Cancer J Clin | 2014 | 24399786 | Yes |
807 | 5007 | 2503.5 | 124.2 | 62.1 | A global optimisation method for robust affine registration of brain images. | M Jenkinson, S Smith | Med Image Anal | 2001 | 11516708 | Yes |
808 | 2500 | 2500.0 | 47.5 | 47.5 | Mechanisms of type-I- and type-II-interferon-mediated signalling. | Leonidas C Platanias | Nat Rev Immunol | 2005 | 15864272 | No |
809 | 4986 | 2493.0 | 141.43 | 70.7 | Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. | J V Durnin, J Womersley | Br J Nutr | 1974 | 4843734 | Yes |
810 | 4983 | 2491.5 | 147.71 | 73.9 | SPSS and SAS procedures for estimating indirect effects in simple mediation models. | Kristopher J Preacher, Andrew F Hayes | Behav Res Methods Instrum Comput | 2004 | 15641418 | Yes |
811 | 4981 | 2490.5 | 181.22 | 90.6 | Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril. | P J Fraker, J C Speck | Biochem Biophys Res Commun | 1978 | 637870 | Yes |
812 | 4973 | 2486.5 | 119.91 | 60.0 | Calculation of protein extinction coefficients from amino acid sequence data. | S C Gill, P H von Hippel | Anal Biochem | 1989 | 2610349 | Yes |
813 | 4972 | 2486.0 | 143.56 | 71.8 | Nonparametric statistical testing of EEG- and MEG-data. | Eric Maris, Robert Oostenveld | J Neurosci Methods | 2007 | 17517438 | Yes |
814 | 4970 | 2485.0 | 96.34 | 48.2 | CDK inhibitors: positive and negative regulators of G1-phase progression. | C J Sherr, J M Roberts | Genes Dev | 1999 | 10385618 | No |
815 | 2477 | 2477.0 | 132.71 | 132.7 | Determination and quantification of content validity. | M R Lynn | Nurs Res | 1986 | 3640358 | Yes |
816 | 2477 | 2477.0 | 59.41 | 59.4 | An index to quantify an individual's scientific research output. | J E Hirsch | Proc Natl Acad Sci U S A | 2005 | 16275915 | Yes |
817 | 2473 | 2473.0 | 91.95 | 92.0 | Missing data analysis: making it work in the real world. | John W Graham | Annu Rev Psychol | 2009 | 18652544 | No |
818 | 4942 | 2471.0 | 131.75 | 65.9 | Alzheimer's disease: the amyloid cascade hypothesis. | J A Hardy, G A Higgins | Science | 1992 | 1566067 | No |
819 | 2470 | 2470.0 | 111.94 | 111.9 | Oxygen-dependent microbial killing by phagocytes (first of two parts). | B M Babior | N Engl J Med | 1978 | 24176 | Yes |
820 | 2469 | 2469.0 | 53.77 | 53.8 | Rab GTPases as coordinators of vesicle traffic. | Harald Stenmark | Nat Rev Mol Cell Biol | 2009 | 19603039 | No |
821 | 9875 | 2468.8 | 236.03 | 59.0 | Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. | C A Lipinski, F Lombardo, B W Dominy, P J Feeney | Adv Drug Deliv Rev | 2001 | 11259830 | No |
822 | 2465 | 2465.0 | 0.0 | 0.0 | Transduction of linked genetic characters of the host by bacteriophage P1. | E S Lennox | Virology | 1955 | 13267987 | Yes |
823 | 2460 | 2460.0 | 82.99 | 83.0 | Doxil®--the first FDA-approved nano-drug: lessons learned. | Yechezkel Barenholz | J Control Release | 2012 | 22484195 | No |
824 | 4916 | 2458.0 | 104.21 | 52.1 | Judgment under Uncertainty: Heuristics and Biases. | A Tversky, D Kahneman | Science | 1974 | 17835457 | Yes |
825 | 7352 | 2450.7 | 209.31 | 69.8 | Bacterial biofilms: a common cause of persistent infections. | J W Costerton, P S Stewart, E P Greenberg | Science | 1999 | 10334980 | No |
826 | 4901 | 2450.5 | 108.53 | 54.3 | Signal integration in the endoplasmic reticulum unfolded protein response. | David Ron, Peter Walter | Nat Rev Mol Cell Biol | 2007 | 17565364 | No |
827 | 2450 | 2450.0 | 78.55 | 78.5 | Plant products as antimicrobial agents. | M M Cowan | Clin Microbiol Rev | 1999 | 10515903 | No |
828 | 2446 | 2446.0 | 0.0 | 0.0 | The information capacity of the human motor system in controlling the amplitude of movement. | P M Fitts | J Exp Psychol | 1954 | 13174710 | Yes |
829 | 4888 | 2444.0 | 69.16 | 34.6 | Periodontal Disease In Pregnancy. I. Prevalence And Severity. | H Loe, J Silness | Acta Odontol Scand | 1963 | 14121956 | Yes |
830 | 2444 | 2444.0 | 111.0 | 111.0 | Structural Model Evaluation and Modification: An Interval Estimation Approach. | J H Steiger | Multivariate Behav Res | 1990 | 26794479 | Yes |
831 | 4887 | 2443.5 | 121.39 | 60.7 | The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. | Karen Bedard, Karl-Heinz Krause | Physiol Rev | 2007 | 17237347 | No |
832 | 2440 | 2440.0 | 57.75 | 57.8 | Causes and consequences of microRNA dysregulation in cancer. | Carlo M Croce | Nat Rev Genet | 2009 | 19763153 | No |
833 | 2439 | 2439.0 | 47.19 | 47.2 | Getting started with yeast. | F Sherman | Methods Enzymol | 1991 | 2005794 | Yes |
834 | 2437 | 2437.0 | 54.09 | 54.1 | Social controls on cell survival and cell death. | M C Raff | Nature | 1992 | 1557121 | No |
835 | 4873 | 2436.5 | 116.19 | 58.1 | A scaling normalization method for differential expression analysis of RNA-seq data. | Mark D Robinson, Alicia Oshlack | Genome Biol | 2010 | 20196867 | Yes |
836 | 2436 | 2436.0 | 65.31 | 65.3 | Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication. | H G Gratzner | Science | 1982 | 7123245 | Yes |
837 | 9729 | 2432.2 | 252.82 | 63.2 | GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation. | Berk Hess, Carsten Kutzner, David van der Spoel, Erik Lindahl | J Chem Theory Comput | 2008 | 26620784 | Yes |
838 | 4861 | 2430.5 | 352.7 | 176.3 | The biology, function, and biomedical applications of exosomes. | Raghu Kalluri, Valerie S LeBleu | Science | 2020 | 32029601 | No |
839 | 2429 | 2429.0 | 80.73 | 80.7 | Working memory. | A Baddeley | Science | 1992 | 1736359 | No |
840 | 2429 | 2429.0 | 54.0 | 54.0 | The inflammatory reflex. | Kevin J Tracey | Nature | 2002 | 12490958 | No |
841 | 2428 | 2428.0 | 61.34 | 61.3 | Network pharmacology: the next paradigm in drug discovery. | Andrew L Hopkins | Nat Chem Biol | 2008 | 18936753 | No |
842 | 4853 | 2426.5 | 143.03 | 71.5 | Missing data: our view of the state of the art. | Joseph L Schafer, John W Graham | Psychol Methods | 2002 | 12090408 | Yes |
843 | 4847 | 2423.5 | 158.06 | 79.0 | Random-effects models for longitudinal data. | N M Laird, J H Ware | Biometrics | 1982 | 7168798 | Yes |
844 | 2422 | 2422.0 | 75.52 | 75.5 | Epidemiology of viral hepatitis and hepatocellular carcinoma. | Hashem B El-Serag | Gastroenterology | 2012 | 22537432 | No |
845 | 4830 | 2415.0 | 92.92 | 46.5 | The phosphatidylinositol 3-Kinase AKT pathway in human cancer. | Igor Vivanco, Charles L Sawyers | Nat Rev Cancer | 2002 | 12094235 | No |
846 | 2413 | 2413.0 | 43.82 | 43.8 | Java Treeview--extensible visualization of microarray data. | Alok J Saldanha | Bioinformatics | 2004 | 15180930 | Yes |
847 | 2412 | 2412.0 | 52.59 | 52.6 | Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. | T Hunter | Cell | 1995 | 7834742 | No |
848 | 2412 | 2412.0 | 154.95 | 154.9 | Obesity: global epidemiology and pathogenesis. | Matthias Blüher | Nat Rev Endocrinol | 2019 | 30814686 | No |
849 | 2411 | 2411.0 | 0.0 | 0.0 | Isolation by Distance. | S Wright | Genetics | 1943 | 17247074 | Yes |
850 | 4815 | 2407.5 | 163.65 | 81.8 | The biofilm matrix. | Hans-Curt Flemming, Jost Wingender | Nat Rev Microbiol | 2010 | 20676145 | No |
851 | 2407 | 2407.0 | 64.11 | 64.1 | Intestinal mucosal barrier function in health and disease. | Jerrold R Turner | Nat Rev Immunol | 2009 | 19855405 | No |
852 | 4811 | 2405.5 | 208.81 | 104.4 | The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. | H P Misra, I Fridovich | J Biol Chem | 1972 | 4623845 | Yes |
853 | 2405 | 2405.0 | 99.03 | 99.0 | The validity and practicality of sun-reactive skin types I through VI. | T B Fitzpatrick | Arch Dermatol | 1988 | 3377516 | Yes |
854 | 2405 | 2405.0 | 50.26 | 50.3 | Cisplatin: mode of cytotoxic action and molecular basis of resistance. | Zahid H Siddik | Oncogene | 2003 | 14576837 | No |
855 | 4803 | 2401.5 | 143.3 | 71.7 | Neural mechanisms of selective visual attention. | R Desimone, J Duncan | Annu Rev Neurosci | 1995 | 7605061 | No |
856 | 4803 | 2401.5 | 94.09 | 47.0 | Lipid rafts and signal transduction. | K Simons, D Toomre | Nat Rev Mol Cell Biol | 2000 | 11413487 | No |
857 | 2401 | 2401.0 | 72.85 | 72.8 | A two process model of sleep regulation. | A A Borbély | Hum Neurobiol | 1982 | 7185792 | Yes |
858 | 2400 | 2400.0 | 139.24 | 139.2 | Toward understanding the origin and evolution of cellular organisms. | Minoru Kanehisa | Protein Sci | 2019 | 31441146 | No |
859 | 4790 | 2395.0 | 134.21 | 67.1 | The number of people with glaucoma worldwide in 2010 and 2020. | H A Quigley, A T Broman | Br J Ophthalmol | 2006 | 16488940 | Yes |
860 | 2390 | 2390.0 | 93.34 | 93.3 | Effective physician-patient communication and health outcomes: a review. | M A Stewart | CMAJ | 1995 | 7728691 | Yes |
861 | 2390 | 2390.0 | 54.67 | 54.7 | A decade of molecular biology of retinoic acid receptors. | P Chambon | FASEB J | 1996 | 8801176 | No |
862 | 2387 | 2387.0 | 43.3 | 43.3 | Targeting RAS signalling pathways in cancer therapy. | Julian Downward | Nat Rev Cancer | 2003 | 12509763 | No |
863 | 2386 | 2386.0 | 61.07 | 61.1 | MYC on the path to cancer. | Chi V Dang | Cell | 2012 | 22464321 | No |
864 | 4768 | 2384.0 | 120.02 | 60.0 | Management of hepatocellular carcinoma. | Jordi Bruix, Morris Sherman | Hepatology | 2005 | 16250051 | No |
865 | 2384 | 2384.0 | 57.15 | 57.1 | Lead- and drug-like compounds: the rule-of-five revolution. | Christopher A Lipinski | Drug Discov Today Technol | 2004 | 24981612 | Yes |
866 | 4764 | 2382.0 | 128.08 | 64.0 | Ab initio molecular-dynamics simulation of the liquid-metal-amorphous-semiconductor transition in germanium. | G Kresse, J Hafner | Phys Rev B Condens Matter | 1994 | 10010505 | Yes |
867 | 2381 | 2381.0 | 113.14 | 113.1 | Abiotic Stress Signaling and Responses in Plants. | Jian-Kang Zhu | Cell | 2016 | 27716505 | No |
868 | 2379 | 2379.0 | 0.0 | 0.0 | Muscle structure and theories of contraction. | A F Huxley | Prog Biophys Biophys Chem | 1957 | 13485191 | Yes |
869 | 2379 | 2379.0 | 51.49 | 51.5 | A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. | Douglas C Wallace | Annu Rev Genet | 2005 | 16285865 | No |
870 | 4751 | 2375.5 | 567.21 | 283.6 | Interactive Tree Of Life (iTOL) v5: an online tool for phylogenetic tree display and annotation. | Ivica Letunic, Peer Bork | Nucleic Acids Res | 2021 | 33885785 | Yes |
871 | 7125 | 2375.0 | 154.66 | 51.6 | The biology of VEGF and its receptors. | Napoleone Ferrara, Hans-Peter Gerber, Jennifer LeCouter | Nat Med | 2003 | 12778165 | No |
872 | 2373 | 2373.0 | 62.29 | 62.3 | A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. | P Chomczynski | Biotechniques | 1993 | 7692896 | Yes |
873 | 2372 | 2372.0 | 49.29 | 49.3 | Molecular physiology of P2X receptors. | R Alan North | Physiol Rev | 2002 | 12270951 | No |
874 | 2368 | 2368.0 | 59.72 | 59.7 | A theory of cortical responses. | Karl Friston | Philos Trans R Soc Lond B Biol Sci | 2005 | 15937014 | No |
875 | 2364 | 2364.0 | 77.29 | 77.3 | A rapid radiochemical method for the determination of choline acetyltransferase. | F Fonnum | J Neurochem | 1975 | 1113118 | Yes |
876 | 2364 | 2364.0 | 51.69 | 51.7 | Mitochondrial diseases in man and mouse. | D C Wallace | Science | 1999 | 10066162 | No |
877 | 2362 | 2362.0 | 97.89 | 97.9 | The Michigan alcoholism screening test: the quest for a new diagnostic instrument. | M L Selzer | Am J Psychiatry | 1971 | 5565851 | Yes |
878 | 2360 | 2360.0 | 57.3 | 57.3 | P-LINCS: A Parallel Linear Constraint Solver for Molecular Simulation. | Berk Hess | J Chem Theory Comput | 2008 | 26619985 | Yes |
879 | 2359 | 2359.0 | 60.08 | 60.1 | Standardized low-resolution brain electromagnetic tomography (sLORETA): technical details. | R D Pascual-Marqui | Methods Find Exp Clin Pharmacol | 2002 | 12575463 | No |
880 | 4717 | 2358.5 | 127.95 | 64.0 | Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. | Michael D Fox, Marcus E Raichle | Nat Rev Neurosci | 2007 | 17704812 | No |
881 | 4714 | 2357.0 | 97.43 | 48.7 | New functions for the matrix metalloproteinases in cancer progression. | Mikala Egeblad, Zena Werb | Nat Rev Cancer | 2002 | 11990853 | No |
882 | 4706 | 2353.0 | 118.14 | 59.1 | Acute-phase proteins and other systemic responses to inflammation. | C Gabay, I Kushner | N Engl J Med | 1999 | 9971870 | No |
883 | 4705 | 2352.5 | 103.61 | 51.8 | AKT/PKB signaling: navigating downstream. | Brendan D Manning, Lewis C Cantley | Cell | 2007 | 17604717 | No |
884 | 7045 | 2348.3 | 69.93 | 23.3 | On The Nature Of Allosteric Transitions: A Plausible Model. | J Monod, J Wyman, J P Changeux | J Mol Biol | 1965 | 14343300 | Yes |
885 | 4696 | 2348.0 | 103.0 | 51.5 | Death receptors: signaling and modulation. | A Ashkenazi, V M Dixit | Science | 1998 | 9721089 | No |
886 | 2347 | 2347.0 | 80.24 | 80.2 | Large-scale brain networks and psychopathology: a unifying triple network model. | Vinod Menon | Trends Cogn Sci | 2011 | 21908230 | No |
887 | 2344 | 2344.0 | 66.56 | 66.6 | Scaffolds in tissue engineering bone and cartilage. | D W Hutmacher | Biomaterials | 2000 | 11071603 | Yes |
888 | 2344 | 2344.0 | 103.41 | 103.4 | Deep learning in neural networks: an overview. | Jürgen Schmidhuber | Neural Netw | 2015 | 25462637 | No |
889 | 4687 | 2343.5 | 172.06 | 86.0 | Self-rated health and mortality: a review of twenty-seven community studies. | E L Idler, Y Benyamini | J Health Soc Behav | 1997 | 9097506 | No |
890 | 4681 | 2340.5 | 124.81 | 62.4 | Application of phylogenetic networks in evolutionary studies. | Daniel H Huson, David Bryant | Mol Biol Evol | 2006 | 16221896 | Yes |
891 | 2339 | 2339.0 | 106.11 | 106.1 | Metazoan MicroRNAs. | David P Bartel | Cell | 2018 | 29570994 | No |
892 | 4677 | 2338.5 | 118.19 | 59.1 | Gold nanoparticles: assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology. | Marie-Christine Daniel, Didier Astruc | Chem Rev | 2004 | 14719978 | No |
893 | 2337 | 2337.0 | 78.11 | 78.1 | Simplified calculation of body-surface area. | R D Mosteller | N Engl J Med | 1987 | 3657876 | Yes |
894 | 4673 | 2336.5 | 88.02 | 44.0 | A novel genetic system to detect protein-protein interactions. | S Fields, O Song | Nature | 1989 | 2547163 | Yes |
895 | 2336 | 2336.0 | 51.97 | 52.0 | The structure and regulation of protein phosphatases. | P Cohen | Annu Rev Biochem | 1989 | 2549856 | No |
896 | 2336 | 2336.0 | 50.21 | 50.2 | Nitric oxide and the immune response. | C Bogdan | Nat Immunol | 2001 | 11577346 | No |
897 | 4670 | 2335.0 | 102.9 | 51.5 | Screening lambdagt recombinant clones by hybridization to single plaques in situ. | W D Benton, R W Davis | Science | 1977 | 322279 | Yes |
898 | 2334 | 2334.0 | 76.0 | 76.0 | Qualitative research: standards, challenges, and guidelines. | K Malterud | Lancet | 2001 | 11513933 | Yes |
899 | 14004 | 2334.0 | 744.0 | 124.0 | DADA2: High-resolution sample inference from Illumina amplicon data. | Benjamin J Callahan, Paul J McMurdie, Michael J Rosen, Andrew W Han, Amy Jo A Johnson, Susan P Holmes | Nat Methods | 2016 | 27214047 | Yes |
900 | 4660 | 2330.0 | 122.74 | 61.4 | Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. | C W Elston, I O Ellis | Histopathology | 1991 | 1757079 | Yes |
901 | 2330 | 2330.0 | 57.3 | 57.3 | Contrasting mechanisms of defense against biotrophic and necrotrophic pathogens. | Jane Glazebrook | Annu Rev Phytopathol | 2005 | 16078883 | No |
902 | 4658 | 2329.0 | 113.58 | 56.8 | Nonparametric permutation tests for functional neuroimaging: a primer with examples. | Thomas E Nichols, Andrew P Holmes | Hum Brain Mapp | 2002 | 11747097 | Yes |
903 | 2326 | 2326.0 | 84.26 | 84.3 | Calmodulin plays a pivotal role in cellular regulation. | W Y Cheung | Science | 1980 | 6243188 | No |
904 | 2325 | 2325.0 | 57.45 | 57.5 | A model for receptor-regulated calcium entry. | J W Putney | Cell Calcium | 1986 | 2420465 | No |
905 | 2325 | 2325.0 | 0.0 | 0.0 | Studies on lysogenesis. I. The mode of phage liberation by lysogenic Escherichia coli. | G Bertani | J Bacteriol | 1951 | 14888646 | Yes |
906 | 2324 | 2324.0 | 65.22 | 65.2 | TGFβ signalling in context. | Joan Massagué | Nat Rev Mol Cell Biol | 2012 | 22992590 | No |
907 | 2323 | 2323.0 | 55.44 | 55.4 | Ischemic cell death in brain neurons. | P Lipton | Physiol Rev | 1999 | 10508238 | No |
908 | 9292 | 2323.0 | 202.68 | 50.7 | Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. | A Krogh, B Larsson, G von Heijne, E L Sonnhammer | J Mol Biol | 2001 | 11152613 | Yes |
909 | 4646 | 2323.0 | 89.84 | 44.9 | Mechanisms of TGF-beta signaling from cell membrane to the nucleus. | Yigong Shi, Joan Massagué | Cell | 2003 | 12809600 | No |
910 | 2322 | 2322.0 | 41.45 | 41.5 | Stereochemistry of cooperative effects in haemoglobin. | M F Perutz | Nature | 1970 | 5528785 | Yes |
911 | 2321 | 2321.0 | 78.43 | 78.4 | Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. | F F Jöbsis | Science | 1977 | 929199 | Yes |
912 | 2321 | 2321.0 | 66.01 | 66.0 | Interleukin-1 and interleukin-1 antagonism. | C A Dinarello | Blood | 1991 | 1826616 | No |
913 | 2319 | 2319.0 | 53.72 | 53.7 | Specification of cerebral cortical areas. | P Rakic | Science | 1988 | 3291116 | No |
914 | 2319 | 2319.0 | 59.09 | 59.1 | The blood-brain barrier in health and chronic neurodegenerative disorders. | Berislav V Zlokovic | Neuron | 2008 | 18215617 | No |
915 | 4636 | 2318.0 | 126.12 | 63.1 | Quantitative film detection of 3H and 14C in polyacrylamide gels by fluorography. | R A Laskey, A D Mills | Eur J Biochem | 1975 | 1175627 | Yes |
916 | 2314 | 2314.0 | 48.62 | 48.6 | NOX enzymes and the biology of reactive oxygen. | J David Lambeth | Nat Rev Immunol | 2004 | 15039755 | No |
917 | 2314 | 2314.0 | 96.05 | 96.0 | What's in a name? Qualitative description revisited. | Margarete Sandelowski | Res Nurs Health | 2010 | 20014004 | Yes |
918 | 2313 | 2313.0 | 27.45 | 27.4 | Mechanism Of Sustained-Action Medication. Theoretical Analysis Of Rate Of Release Of Solid Drugs Dispersed In Solid Matrices. | T Higuchi | J Pharm Sci | 1963 | 14088963 | Yes |
919 | 4621 | 2310.5 | 124.18 | 62.1 | A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. | Y Matsumura, H Maeda | Cancer Res | 1986 | 2946403 | Yes |
920 | 2310 | 2310.0 | 56.29 | 56.3 | Animal mitochondrial genomes. | J L Boore | Nucleic Acids Res | 1999 | 10101183 | No |
921 | 2308 | 2308.0 | 55.81 | 55.8 | The anatomy and taxonomy of protein structure. | J S Richardson | Adv Protein Chem | 1981 | 7020376 | No |
922 | 4611 | 2305.5 | 76.24 | 38.1 | On the size of the active site in proteases. I. Papain. | I Schechter, A Berger | Biochem Biophys Res Commun | 1967 | 6035483 | Yes |
923 | 2305 | 2305.0 | 63.64 | 63.6 | Inositol phospholipids and cell surface receptor function. | R H Michell | Biochim Biophys Acta | 1975 | 164246 | No |
924 | 4610 | 2305.0 | 169.29 | 84.6 | The attention system of the human brain. | M I Posner, S E Petersen | Annu Rev Neurosci | 1990 | 2183676 | No |
925 | 2304 | 2304.0 | 73.24 | 73.2 | Spinal and supraspinal factors in human muscle fatigue. | S C Gandevia | Physiol Rev | 2001 | 11581501 | No |
926 | 4603 | 2301.5 | 72.07 | 36.0 | High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study. | M N Berry, D S Friend | J Cell Biol | 1969 | 4900611 | Yes |
927 | 4598 | 2299.0 | 86.86 | 43.4 | The interpretation of protein structures: estimation of static accessibility. | B Lee, F M Richards | J Mol Biol | 1971 | 5551392 | Yes |
928 | 2299 | 2299.0 | 57.04 | 57.0 | Bcl-2 and the regulation of programmed cell death. | J C Reed | J Cell Biol | 1994 | 8294493 | No |
929 | 2298 | 2298.0 | 74.68 | 74.7 | Eye movements in reading and information processing: 20 years of research. | K Rayner | Psychol Bull | 1998 | 9849112 | No |
930 | 2298 | 2298.0 | 71.43 | 71.4 | Human error: models and management. | J Reason | BMJ | 2000 | 10720363 | Yes |
931 | 2294 | 2294.0 | 60.32 | 60.3 | The importance of selenium to human health. | M P Rayman | Lancet | 2000 | 10963212 | No |
932 | 4582 | 2291.0 | 115.2 | 57.6 | A receptor-mediated pathway for cholesterol homeostasis. | M S Brown, J L Goldstein | Science | 1986 | 3513311 | No |
933 | 2291 | 2291.0 | 68.16 | 68.2 | PsychoPy--Psychophysics software in Python. | Jonathan W Peirce | J Neurosci Methods | 2007 | 17254636 | Yes |
934 | 4577 | 2288.5 | 106.61 | 53.3 | Protein misfolding, functional amyloid, and human disease. | Fabrizio Chiti, Christopher M Dobson | Annu Rev Biochem | 2006 | 16756495 | No |
935 | 2285 | 2285.0 | 60.01 | 60.0 | Epidemiology of insomnia: what we know and what we still need to learn. | Maurice M Ohayon | Sleep Med Rev | 2002 | 12531146 | Yes |
936 | 2285 | 2285.0 | 60.21 | 60.2 | Carbonic anhydrases: novel therapeutic applications for inhibitors and activators. | Claudiu T Supuran | Nat Rev Drug Discov | 2008 | 18167490 | No |
937 | 2282 | 2282.0 | 45.29 | 45.3 | SV40-transformed simian cells support the replication of early SV40 mutants. | Y Gluzman | Cell | 1981 | 6260373 | Yes |
938 | 4563 | 2281.5 | 94.92 | 47.5 | Mass spectrometry-based proteomics. | Ruedi Aebersold, Matthias Mann | Nature | 2003 | 12634793 | No |
939 | 2281 | 2281.0 | 42.61 | 42.6 | Histone acetylation in chromatin structure and transcription. | M Grunstein | Nature | 1997 | 9311776 | No |
940 | 2280 | 2280.0 | 71.18 | 71.2 | Reactive oxygen species and the central nervous system. | B Halliwell | J Neurochem | 1992 | 1402908 | No |
941 | 4557 | 2278.5 | 129.96 | 65.0 | Distributed hierarchical processing in the primate cerebral cortex. | D J Felleman, D C Van Essen | Cereb Cortex | 1991 | 1822724 | No |
942 | 2278 | 2278.0 | 76.27 | 76.3 | Glutamate, nitric oxide and cell-cell signalling in the nervous system. | J Garthwaite | Trends Neurosci | 1991 | 1708538 | No |
943 | 2278 | 2278.0 | 66.02 | 66.0 | Social determinants of health inequalities. | Michael Marmot | Lancet | 2005 | 15781105 | Yes |
944 | 4553 | 2276.5 | 101.46 | 50.7 | Brown adipose tissue: function and physiological significance. | Barbara Cannon, Jan Nedergaard | Physiol Rev | 2004 | 14715917 | No |
945 | 4549 | 2274.5 | 116.39 | 58.2 | ATHENA, ARTEMIS, HEPHAESTUS: data analysis for X-ray absorption spectroscopy using IFEFFIT. | B Ravel, M Newville | J Synchrotron Radiat | 2005 | 15968136 | Yes |
946 | 2273 | 2273.0 | 44.57 | 44.6 | The molecular biology of memory storage: a dialogue between genes and synapses. | E R Kandel | Science | 2001 | 11691980 | No |
947 | 9080 | 2270.0 | 570.88 | 142.7 | Rayyan-a web and mobile app for systematic reviews. | Mourad Ouzzani, Hossam Hammady, Zbys Fedorowicz, Ahmed Elmagarmid | Syst Rev | 2016 | 27919275 | Yes |
948 | 2268 | 2268.0 | 58.68 | 58.7 | Working memory: looking back and looking forward. | Alan Baddeley | Nat Rev Neurosci | 2003 | 14523382 | No |
949 | 2265 | 2265.0 | 65.63 | 65.6 | Hazards of heavy metal contamination. | Lars Järup | Br Med Bull | 2003 | 14757716 | No |
950 | 9043 | 2260.8 | 182.77 | 45.7 | WebLogo: a sequence logo generator. | Gavin E Crooks, Gary Hon, John-Marc Chandonia, Steven E Brenner | Genome Res | 2004 | 15173120 | Yes |
951 | 2260 | 2260.0 | 48.8 | 48.8 | Chemokines and leukocyte traffic. | M Baggiolini | Nature | 1998 | 9560152 | No |
952 | 2260 | 2260.0 | 0.0 | 0.0 | [Rapid physiological coagulation method in determination of fibrinogen]. | A Clauss | Acta Haematol | 1957 | 13434757 | Yes |
953 | 2259 | 2259.0 | 139.29 | 139.3 | Application of a microtechnique to viral serological investigations. | J L Sever | J Immunol | 1962 | 13910995 | Yes |
954 | 2258 | 2258.0 | 68.68 | 68.7 | Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM. | R A DeFronzo | Diabetes | 1988 | 3289989 | No |
955 | 4513 | 2256.5 | 114.92 | 57.5 | Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. | M Matsuda, R A DeFronzo | Diabetes Care | 1999 | 10480510 | Yes |
956 | 2255 | 2255.0 | 135.69 | 135.7 | Presidential Address-1976. Social support as a moderator of life stress. | S Cobb | Psychosom Med | 1976 | 981490 | Yes |
957 | 2251 | 2251.0 | 70.69 | 70.7 | Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. | W A Craig | Clin Infect Dis | 1998 | 9455502 | No |
958 | 2250 | 2250.0 | 56.07 | 56.1 | RGD and other recognition sequences for integrins. | E Ruoslahti | Annu Rev Cell Dev Biol | 1996 | 8970741 | No |
959 | 2250 | 2250.0 | 89.55 | 89.5 | Comments on 'KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease'. | Konrad M Andrassy | Kidney Int | 2013 | 23989362 | Yes |
960 | 2249 | 2249.0 | 115.98 | 116.0 | Electroimmuno assay. | C B Laurell | Scand J Clin Lab Invest Suppl | 1972 | 4114358 | Yes |
961 | 2248 | 2248.0 | 84.01 | 84.0 | Specific impairments of planning. | T Shallice | Philos Trans R Soc Lond B Biol Sci | 1982 | 6125971 | Yes |
962 | 4496 | 2248.0 | 102.91 | 51.5 | A simple and very efficient method for generating cDNA libraries. | U Gubler, B J Hoffman | Gene | 1983 | 6198242 | Yes |
963 | 4493 | 2246.5 | 108.36 | 54.2 | Regulation of the mevalonate pathway. | J L Goldstein, M S Brown | Nature | 1990 | 1967820 | No |
964 | 2245 | 2245.0 | 53.15 | 53.1 | Protein kinase C and lipid signaling for sustained cellular responses. | Y Nishizuka | FASEB J | 1995 | 7737456 | No |
965 | 2244 | 2244.0 | 61.39 | 61.4 | Molecular diversity of glutamate receptors and implications for brain function. | S Nakanishi | Science | 1992 | 1329206 | No |
966 | 4488 | 2244.0 | 88.5 | 44.2 | Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. | T V Bliss, T Lomo | J Physiol | 1973 | 4727084 | Yes |
967 | 2242 | 2242.0 | 57.17 | 57.2 | Pancreatic cancer. | Manuel Hidalgo | N Engl J Med | 2010 | 20427809 | No |
968 | 4483 | 2241.5 | 88.86 | 44.4 | The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin. | J A Spudich, S Watt | J Biol Chem | 1971 | 4254541 | Yes |
969 | 2240 | 2240.0 | 60.39 | 60.4 | Biofilms: microbial life on surfaces. | Rodney M Donlan | Emerg Infect Dis | 2002 | 12194761 | No |
970 | 2239 | 2239.0 | 41.76 | 41.8 | Shelterin: the protein complex that shapes and safeguards human telomeres. | Titia de Lange | Genes Dev | 2005 | 16166375 | No |
971 | 4474 | 2237.0 | 39.38 | 19.7 | A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. | J E TILL, E A McCULLOCH | Radiat Res | 1961 | 13776896 | Yes |
972 | 2236 | 2236.0 | 54.84 | 54.8 | Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide to nitrocellulose. | J Kyhse-Andersen | J Biochem Biophys Methods | 1984 | 6530509 | Yes |
973 | 2235 | 2235.0 | 110.08 | 110.1 | Mechanisms of action of transmitters and other substances on smooth muscle. | T B Bolton | Physiol Rev | 1979 | 37533 | No |
974 | 2235 | 2235.0 | 72.7 | 72.7 | Keratoconus. | Y S Rabinowitz | Surv Ophthalmol | 1998 | 9493273 | No |
975 | 4469 | 2234.5 | 129.05 | 64.5 | Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. | C J Murray, A D Lopez | Lancet | 1997 | 9167458 | Yes |
976 | 17874 | 2234.2 | 562.48 | 70.3 | The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. | D M Nathan, S Genuth, J Lachin, P Cleary, O Crofford, M Davis, L Rand, C Siebert | N Engl J Med | 1993 | 8366922 | Yes |
977 | 2234 | 2234.0 | 63.76 | 63.8 | Hypoxia-inducible factors in physiology and medicine. | Gregg L Semenza | Cell | 2012 | 22304911 | No |
978 | 2233 | 2233.0 | 62.59 | 62.6 | Infrared spectroscopy of proteins. | Andreas Barth | Biochim Biophys Acta | 2007 | 17692815 | No |
979 | 2232 | 2232.0 | 77.22 | 77.2 | Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases. | B N Ames | Science | 1983 | 6351251 | No |
980 | 6680 | 2226.7 | 258.05 | 86.0 | Glucose clamp technique: a method for quantifying insulin secretion and resistance. | R A DeFronzo, J D Tobin, R Andres | Am J Physiol | 1979 | 382871 | Yes |
981 | 2226 | 2226.0 | 49.01 | 49.0 | The regulation of AP-1 activity by mitogen-activated protein kinases. | M Karin | J Biol Chem | 1995 | 7622446 | No |
982 | 6677 | 2225.7 | 184.83 | 61.6 | Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. | F E Harrell, K L Lee, D B Mark | Stat Med | 1996 | 8668867 | No |
983 | 8902 | 2225.5 | 190.9 | 47.7 | MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform. | Kazutaka Katoh, Kazuharu Misawa, Kei-ichi Kuma, Takashi Miyata | Nucleic Acids Res | 2002 | 12136088 | Yes |
984 | 2225 | 2225.0 | 90.1 | 90.1 | Role of Streptococcus mutans in human dental decay. | W J Loesche | Microbiol Rev | 1986 | 3540569 | No |
985 | 4448 | 2224.0 | 98.25 | 49.1 | Organization and expression of eucaryotic split genes coding for proteins. | R Breathnach, P Chambon | Annu Rev Biochem | 1981 | 6791577 | No |
986 | 2224 | 2224.0 | 88.0 | 88.0 | Approximate entropy as a measure of system complexity. | S M Pincus | Proc Natl Acad Sci U S A | 1991 | 11607165 | Yes |
987 | 2224 | 2224.0 | 56.86 | 56.9 | The physiology of glucagon-like peptide 1. | Jens Juul Holst | Physiol Rev | 2007 | 17928588 | No |
988 | 35559 | 2222.4 | 1138.38 | 71.1 | Fiji: an open-source platform for biological-image analysis. | Johannes Schindelin, Ignacio Arganda-Carreras, Erwin Frise, Verena Kaynig, Mark Longair, Tobias Pietzsch, Stephan Preibisch, Curtis Rueden, Stephan Saalfeld, Benjamin Schmid, Jean-Yves Tinevez, Daniel James White, Volker Hartenstein, Kevin Eliceiri, Pavel Tomancak, Albert Cardona | Nat Methods | 2012 | 22743772 | Yes |
989 | 2220 | 2220.0 | 68.05 | 68.0 | Biodiesel from microalgae. | Yusuf Chisti | Biotechnol Adv | 2007 | 17350212 | No |
990 | 19955 | 2217.2 | 908.95 | 101.0 | Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. | Jacques Ferlay, Isabelle Soerjomataram, Rajesh Dikshit, Sultan Eser, Colin Mathers, Marise Rebelo, Donald Maxwell Parkin, David Forman, Freddie Bray | Int J Cancer | 2015 | 25220842 | Yes |
991 | 2217 | 2217.0 | 52.52 | 52.5 | Mechanisms and genes of cellular suicide. | H Steller | Science | 1995 | 7878463 | No |
992 | 2214 | 2214.0 | 65.75 | 65.8 | Diagnosis of Alzheimer's disease. | Z S Khachaturian | Arch Neurol | 1985 | 2864910 | Yes |
993 | 2213 | 2213.0 | 54.86 | 54.9 | The extracellular matrix: not just pretty fibrils. | Richard O Hynes | Science | 2009 | 19965464 | No |
994 | 2209 | 2209.0 | 47.67 | 47.7 | Intracellular aspects of the process of protein synthesis. | G Palade | Science | 1975 | 1096303 | No |
995 | 2208 | 2208.0 | 47.02 | 47.0 | Complement. First of two parts. | M J Walport | N Engl J Med | 2001 | 11287977 | No |
996 | 4414 | 2207.0 | 98.99 | 49.5 | The Bcl-2 protein family: arbiters of cell survival. | J M Adams, S Cory | Science | 1998 | 9735050 | No |
997 | 2204 | 2204.0 | 83.69 | 83.7 | Role of endothelium in responses of vascular smooth muscle. | R F Furchgott | Circ Res | 1983 | 6313250 | No |
998 | 4408 | 2204.0 | 105.6 | 52.8 | Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. | Michael T Lin, M Flint Beal | Nature | 2006 | 17051205 | No |
999 | 6607 | 2202.3 | 205.8 | 68.6 | Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire. | R L Spitzer, K Kroenke, J B Williams | JAMA | 1999 | 10568646 | Yes |
1000 | 2201 | 2201.0 | 56.72 | 56.7 | Removal of fatty acids from serum albumin by charcoal treatment. | R F Chen | J Biol Chem | 1967 | 6016603 | Yes |
1001 | 2201 | 2201.0 | 70.81 | 70.8 | Optimal caliper widths for propensity-score matching when estimating differences in means and differences in proportions in observational studies. | Peter C Austin | Pharm Stat | 2011 | 20925139 | Yes |
1002 | 4401 | 2200.5 | 148.4 | 74.2 | Shifting the genomic gold standard for the prokaryotic species definition. | Michael Richter, Ramon Rosselló-Móra | Proc Natl Acad Sci U S A | 2009 | 19855009 | Yes |
1003 | 2200 | 2200.0 | 80.06 | 80.1 | UCLA Loneliness Scale (Version 3): reliability, validity, and factor structure. | D W Russell | J Pers Assess | 1996 | 8576833 | Yes |
1004 | 6598 | 2199.3 | 195.2 | 65.1 | The brain's default network: anatomy, function, and relevance to disease. | Randy L Buckner, Jessica R Andrews-Hanna, Daniel L Schacter | Ann N Y Acad Sci | 2008 | 18400922 | No |
1005 | 2197 | 2197.0 | 67.97 | 68.0 | Prooxidant states and tumor promotion. | P A Cerutti | Science | 1985 | 2981433 | No |
1006 | 2197 | 2197.0 | 53.89 | 53.9 | Using circular dichroism spectra to estimate protein secondary structure. | Norma J Greenfield | Nat Protoc | 2006 | 17406547 | Yes |
1007 | 4392 | 2196.0 | 76.67 | 38.3 | Variations in pattern of pubertal changes in girls. | W A Marshall, J M Tanner | Arch Dis Child | 1969 | 5785179 | Yes |
1008 | 4389 | 2194.5 | 95.51 | 47.8 | Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. | F Sallusto, A Lanzavecchia | J Exp Med | 1994 | 8145033 | Yes |
1009 | 2194 | 2194.0 | 48.61 | 48.6 | Chemokines. | B J Rollins | Blood | 1997 | 9242519 | No |
1010 | 2194 | 2194.0 | 61.06 | 61.1 | Hybrid porous solids: past, present, future. | Gérard Férey | Chem Soc Rev | 2008 | 18197340 | Yes |
1011 | 2193 | 2193.0 | 79.07 | 79.1 | Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminals. | H W Steinbusch | Neuroscience | 1981 | 7017455 | Yes |
1012 | 2188 | 2188.0 | 52.71 | 52.7 | Breast cancer and hormone-replacement therapy in the Million Women Study. | Valerie Beral | Lancet | 2003 | 12927427 | Yes |
1013 | 2187 | 2187.0 | 66.5 | 66.5 | Fetal origins of coronary heart disease. | D J Barker | BMJ | 1995 | 7613432 | No |
1014 | 4373 | 2186.5 | 103.72 | 51.9 | Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. | Hashem B El-Serag, K Lenhard Rudolph | Gastroenterology | 2007 | 17570226 | No |
1015 | 2184 | 2184.0 | 48.49 | 48.5 | A clearer vision for in vivo imaging. | R Weissleder | Nat Biotechnol | 2001 | 11283581 | No |
1016 | 8734 | 2183.5 | 209.03 | 52.3 | Matrix elasticity directs stem cell lineage specification. | Adam J Engler, Shamik Sen, H Lee Sweeney, Dennis E Discher | Cell | 2006 | 16923388 | Yes |
1017 | 2183 | 2183.0 | 90.84 | 90.8 | A systematic method for clinical description and classification of personality variants. A proposal. | C R Cloninger | Arch Gen Psychiatry | 1987 | 3579504 | Yes |
1018 | 4365 | 2182.5 | 118.99 | 59.5 | Autophagy: renovation of cells and tissues. | Noboru Mizushima, Masaaki Komatsu | Cell | 2011 | 22078875 | No |
1019 | 4365 | 2182.5 | 152.06 | 76.0 | Deciphering key features in protein structures with the new ENDscript server. | Xavier Robert, Patrice Gouet | Nucleic Acids Res | 2014 | 24753421 | Yes |
1020 | 4364 | 2182.0 | 0.0 | 0.0 | Loss of recent memory after bilateral hippocampal lesions. | W B Scoville, B Milner | J Neurol Neurosurg Psychiatry | 1957 | 13406589 | Yes |
1021 | 2181 | 2181.0 | 65.99 | 66.0 | Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. | Leonardo Pantoni | Lancet Neurol | 2010 | 20610345 | No |
1022 | 6541 | 2180.3 | 285.62 | 95.2 | Fast and sensitive protein alignment using DIAMOND. | Benjamin Buchfink, Chao Xie, Daniel H Huson | Nat Methods | 2015 | 25402007 | Yes |
1023 | 2179 | 2179.0 | 58.79 | 58.8 | The episodic buffer: a new component of working memory? | A Baddeley | Trends Cogn Sci | 2000 | 11058819 | Yes |
1024 | 2173 | 2173.0 | 56.69 | 56.7 | The molecular pathology of Alzheimer's disease. | D J Selkoe | Neuron | 1991 | 1673054 | No |
1025 | 2170 | 2170.0 | 60.36 | 60.4 | Superoxide radical and superoxide dismutases. | I Fridovich | Annu Rev Biochem | 1995 | 7574505 | No |
1026 | 2169 | 2169.0 | 55.14 | 55.1 | Descending control of pain. | Mark J Millan | Prog Neurobiol | 2002 | 12034378 | No |
1027 | 2168 | 2168.0 | 46.11 | 46.1 | Theta oscillations in the hippocampus. | György Buzsáki | Neuron | 2002 | 11832222 | No |
1028 | 4334 | 2167.0 | 182.16 | 91.1 | The Health Belief Model: a decade later. | N K Janz, M H Becker | Health Educ Q | 1984 | 6392204 | No |
1029 | 6500 | 2166.7 | 197.19 | 65.7 | Universal solvation model based on solute electron density and on a continuum model of the solvent defined by the bulk dielectric constant and atomic surface tensions. | Aleksandr V Marenich, Christopher J Cramer, Donald G Truhlar | J Phys Chem B | 2009 | 19366259 | Yes |
1030 | 2166 | 2166.0 | 93.56 | 93.6 | The Children's Depression, Inventory (CDI). | M Kovacs | Psychopharmacol Bull | 1985 | 4089116 | Yes |
1031 | 4326 | 2163.0 | 147.83 | 73.9 | Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method. | R B Devereux, N Reichek | Circulation | 1977 | 138494 | Yes |
1032 | 6485 | 2161.7 | 132.49 | 44.2 | EMBOSS: the European Molecular Biology Open Software Suite. | P Rice, I Longden, A Bleasby | Trends Genet | 2000 | 10827456 | Yes |
1033 | 2159 | 2159.0 | 41.76 | 41.8 | Protein modules and signalling networks. | T Pawson | Nature | 1995 | 7531822 | No |
1034 | 2158 | 2158.0 | 71.2 | 71.2 | A classification of glycosyl hydrolases based on amino acid sequence similarities. | B Henrissat | Biochem J | 1991 | 1747104 | Yes |
1035 | 6470 | 2156.7 | 186.89 | 62.3 | Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. | C E Murry, R B Jennings, K A Reimer | Circulation | 1986 | 3769170 | Yes |
1036 | 4311 | 2155.5 | 128.98 | 64.5 | Macrophage plasticity and polarization: in vivo veritas. | Antonio Sica, Alberto Mantovani | J Clin Invest | 2012 | 22378047 | No |
1037 | 12932 | 2155.3 | 288.79 | 48.1 | NMRPipe: a multidimensional spectral processing system based on UNIX pipes. | F Delaglio, S Grzesiek, G W Vuister, G Zhu, J Pfeifer, A Bax | J Biomol NMR | 1995 | 8520220 | Yes |
1038 | 2153 | 2153.0 | 47.68 | 47.7 | Comparison of the predicted and observed secondary structure of T4 phage lysozyme. | B W Matthews | Biochim Biophys Acta | 1975 | 1180967 | Yes |
1039 | 2153 | 2153.0 | 39.83 | 39.8 | NK cell recognition. | Lewis L Lanier | Annu Rev Immunol | 2005 | 15771571 | No |
1040 | 4305 | 2152.5 | 111.5 | 55.8 | The inflammasomes. | Kate Schroder, Jurg Tschopp | Cell | 2010 | 20303873 | No |
1041 | 2152 | 2152.0 | 49.92 | 49.9 | Metabolomics--the link between genotypes and phenotypes. | Oliver Fiehn | Plant Mol Biol | 2002 | 11860207 | No |
1042 | 2152 | 2152.0 | 31.19 | 31.2 | Sedimentation Studies Of The Size And Shape Of Dna. | F W Studier | J Mol Biol | 1965 | 14290352 | Yes |
1043 | 2152 | 2152.0 | 0.0 | 0.0 | Analysis of tissue and arterial blood temperatures in the resting human forearm. | H H Pennes | J Appl Physiol | 1948 | 18887578 | Yes |
1044 | 2151 | 2151.0 | 49.68 | 49.7 | Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. | G Trinchieri | Annu Rev Immunol | 1995 | 7612223 | No |
1045 | 6448 | 2149.3 | 272.95 | 91.0 | Scoping studies: advancing the methodology. | Danielle Levac, Heather Colquhoun, Kelly K O'Brien | Implement Sci | 2010 | 20854677 | Yes |
1046 | 4297 | 2148.5 | 104.0 | 52.0 | Measuring the thickness of the human cerebral cortex from magnetic resonance images. | B Fischl, A M Dale | Proc Natl Acad Sci U S A | 2000 | 10984517 | Yes |
1047 | 2148 | 2148.0 | 48.68 | 48.7 | Pathways towards and away from Alzheimer's disease. | Mark P Mattson | Nature | 2004 | 15295589 | No |
1048 | 4294 | 2147.0 | 83.7 | 41.9 | Smad-dependent and Smad-independent pathways in TGF-beta family signalling. | Rik Derynck, Ying E Zhang | Nature | 2003 | 14534577 | No |
1049 | 2147 | 2147.0 | 51.5 | 51.5 | Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences. | Edward V Loftus | Gastroenterology | 2004 | 15168363 | Yes |
1050 | 2143 | 2143.0 | 115.75 | 115.8 | The assessment of clinical skills/competence/performance. | G E Miller | Acad Med | 1990 | 2400509 | Yes |
1051 | 4284 | 2142.0 | 100.68 | 50.3 | Assembly of asparagine-linked oligosaccharides. | R Kornfeld, S Kornfeld | Annu Rev Biochem | 1985 | 3896128 | No |
1052 | 4280 | 2140.0 | 80.48 | 40.2 | The fundamental role of epigenetic events in cancer. | Peter A Jones, Stephen B Baylin | Nat Rev Genet | 2002 | 12042769 | No |
1053 | 2140 | 2140.0 | 0.0 | 0.0 | A new specific color reaction of hexuronic acids. | Z Dische | J Biol Chem | 1947 | 20281638 | Yes |
1054 | 2139 | 2139.0 | 133.64 | 133.6 | High-performance medicine: the convergence of human and artificial intelligence. | Eric J Topol | Nat Med | 2019 | 30617339 | No |
1055 | 4277 | 2138.5 | 73.29 | 36.6 | A Simplified Lead Citrate Stain For Use In Electron Microscopy. | J H Venable, R Coggeshall | J Cell Biol | 1965 | 14287192 | Yes |
1056 | 6414 | 2138.0 | 149.98 | 50.0 | APE: Analyses of Phylogenetics and Evolution in R language. | Emmanuel Paradis, Julien Claude, Korbinian Strimmer | Bioinformatics | 2004 | 14734327 | Yes |
1057 | 2136 | 2136.0 | 62.44 | 62.4 | The energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers. | D E Atkinson | Biochemistry | 1968 | 4972613 | Yes |
1058 | 6407 | 2135.7 | 162.51 | 54.2 | GUS fusions: beta-glucuronidase as a sensitive and versatile gene fusion marker in higher plants. | R A Jefferson, T A Kavanagh, M W Bevan | EMBO J | 1987 | 3327686 | Yes |
1059 | 4270 | 2135.0 | 106.95 | 53.5 | Function and activation of NF-kappa B in the immune system. | P A Baeuerle, T Henkel | Annu Rev Immunol | 1994 | 8011280 | No |
1060 | 2135 | 2135.0 | 58.75 | 58.8 | Japanese Classification of Gastric Carcinoma - 2nd English Edition - | Japanese Gastric Cancer Association | Gastric Cancer | 1998 | 11957040 | Yes |
1061 | 6403 | 2134.3 | 131.34 | 43.8 | Immunochemical quantitation of antigens by single radial immunodiffusion. | G Mancini, A O Carbonara, J F Heremans | Immunochemistry | 1965 | 4956917 | Yes |
1062 | 4261 | 2130.5 | 135.18 | 67.6 | A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. | Gary J Bennett, Y-K Xie | Pain | 1988 | 2837713 | Yes |
1063 | 6385 | 2128.3 | 146.19 | 48.7 | MOLMOL: a program for display and analysis of macromolecular structures. | R Koradi, M Billeter, K Wüthrich | J Mol Graph | 1996 | 8744573 | Yes |
1064 | 4254 | 2127.0 | 122.45 | 61.2 | Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. | J S Beckman, W H Koppenol | Am J Physiol | 1996 | 8944624 | No |
1065 | 2126 | 2126.0 | 41.99 | 42.0 | Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. | Shimon Sakaguchi | Nat Immunol | 2005 | 15785760 | No |
1066 | 4250 | 2125.0 | 82.64 | 41.3 | Network biology: understanding the cell's functional organization. | Albert-László Barabási, Zoltán N Oltvai | Nat Rev Genet | 2004 | 14735121 | No |
1067 | 6358 | 2119.3 | 264.97 | 88.3 | Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test. | B N Ames, J Mccann, E Yamasaki | Mutat Res | 1975 | 768755 | Yes |
1068 | 4237 | 2118.5 | 179.9 | 90.0 | The MOS social support survey. | C D Sherbourne, A L Stewart | Soc Sci Med | 1991 | 2035047 | Yes |
1069 | 4236 | 2118.0 | 121.89 | 60.9 | Oncology meets immunology: the cancer-immunity cycle. | Daniel S Chen, Ira Mellman | Immunity | 2013 | 23890059 | No |
1070 | 2117 | 2117.0 | 64.07 | 64.1 | The unbiased estimation of number and sizes of arbitrary particles using the disector. | D C Sterio | J Microsc | 1984 | 6737468 | Yes |
1071 | 2115 | 2115.0 | 35.23 | 35.2 | Methods for the quantitative estimation of N-acetylneuraminic acid and their application to hydrolysates of sialomucoids. | D Aminoff | Biochem J | 1961 | 13860975 | Yes |
1072 | 4229 | 2114.5 | 121.52 | 60.8 | Angiogenic factors. | J Folkman, M Klagsbrun | Science | 1987 | 2432664 | No |
1073 | 2114 | 2114.0 | 50.93 | 50.9 | Dopamine, learning and motivation. | Roy A Wise | Nat Rev Neurosci | 2004 | 15152198 | No |
1074 | 2112 | 2112.0 | 75.02 | 75.0 | International experiences with the Hospital Anxiety and Depression Scale--a review of validation data and clinical results. | C Herrmann | J Psychosom Res | 1997 | 9055211 | No |
1075 | 2111 | 2111.0 | 94.5 | 94.5 | The brain's default mode network. | Marcus E Raichle | Annu Rev Neurosci | 2015 | 25938726 | No |
1076 | 6331 | 2110.3 | 117.82 | 39.3 | Control of regulatory T cell development by the transcription factor Foxp3. | Shohei Hori, Takashi Nomura, Shimon Sakaguchi | Science | 2003 | 12522256 | Yes |
1077 | 2110 | 2110.0 | 42.43 | 42.4 | Chemiosmotic coupling in oxidative and photosynthetic phosphorylation. | P Mitchell | Biol Rev Camb Philos Soc | 1966 | 5329743 | No |
1078 | 2110 | 2110.0 | 44.43 | 44.4 | Mammalian G1 cyclins. | C J Sherr | Cell | 1993 | 8513492 | No |
1079 | 4214 | 2107.0 | 106.8 | 53.4 | Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. | E Lander, L Kruglyak | Nat Genet | 1995 | 7581446 | Yes |
1080 | 2105 | 2105.0 | 43.07 | 43.1 | The lasso method for variable selection in the Cox model. | R Tibshirani | Stat Med | 1997 | 9044528 | Yes |
1081 | 8411 | 2102.8 | 400.77 | 100.2 | The Satisfaction With Life Scale. | E Diener, R A Emmons, R J Larsen, S Griffin | J Pers Assess | 1985 | 16367493 | Yes |
1082 | 2102 | 2102.0 | 57.73 | 57.7 | The plasma lecithins:cholesterol acyltransferase reaction. | J A Glomset | J Lipid Res | 1968 | 4868699 | No |
1083 | 2099 | 2099.0 | 42.45 | 42.5 | Role of angiogenesis in tumor growth and metastasis. | Judah Folkman | Semin Oncol | 2002 | 12516034 | No |
1084 | 2098 | 2098.0 | 49.43 | 49.4 | Patterns of amino acids near signal-sequence cleavage sites. | G von Heijne | Eur J Biochem | 1983 | 6852022 | Yes |
1085 | 2098 | 2098.0 | 47.35 | 47.4 | Follicular helper CD4 T cells (TFH). | Shane Crotty | Annu Rev Immunol | 2011 | 21314428 | No |
1086 | 2097 | 2097.0 | 83.67 | 83.7 | A clinically based classification system for acute pancreatitis. Summary of the International Symposium on Acute Pancreatitis, Atlanta, Ga, September 11 through 13, 1992. | E L Bradley | Arch Surg | 1993 | 8489394 | No |
1087 | 4188 | 2094.0 | 110.31 | 55.2 | The unfolded protein response: from stress pathway to homeostatic regulation. | Peter Walter, David Ron | Science | 2011 | 22116877 | No |
1088 | 4183 | 2091.5 | 125.08 | 62.5 | Development of a new resilience scale: the Connor-Davidson Resilience Scale (CD-RISC). | Kathryn M Connor, Jonathan R T Davidson | Depress Anxiety | 2003 | 12964174 | Yes |
1089 | 2091 | 2091.0 | 50.95 | 51.0 | Drug-like properties and the causes of poor solubility and poor permeability. | C A Lipinski | J Pharmacol Toxicol Methods | 2000 | 11274893 | No |
1090 | 4180 | 2090.0 | 101.02 | 50.5 | Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. | G G Glenner, C W Wong | Biochem Biophys Res Commun | 1984 | 6375662 | Yes |
1091 | 4180 | 2090.0 | 186.67 | 93.3 | Stages and processes of self-change of smoking: toward an integrative model of change. | J O Prochaska, C C DiClemente | J Consult Clin Psychol | 1983 | 6863699 | Yes |
1092 | 4179 | 2089.5 | 109.48 | 54.7 | The heat-shock proteins. | S Lindquist, E A Craig | Annu Rev Genet | 1988 | 2853609 | No |
1093 | 6267 | 2089.0 | 185.81 | 61.9 | Arlequin (version 3.0): an integrated software package for population genetics data analysis. | Laurent Excoffier, Guillaume Laval, Stefan Schneider | Evol Bioinform Online | 2007 | 19325852 | Yes |
1094 | 4178 | 2089.0 | 118.53 | 59.3 | Wnt/β-catenin signaling and disease. | Hans Clevers, Roel Nusse | Cell | 2012 | 22682243 | No |
1095 | 2087 | 2087.0 | 52.02 | 52.0 | Accurate description of van der Waals complexes by density functional theory including empirical corrections. | Stefan Grimme | J Comput Chem | 2004 | 15224390 | Yes |
1096 | 4173 | 2086.5 | 78.87 | 39.4 | SIFT: Predicting amino acid changes that affect protein function. | Pauline C Ng, Steven Henikoff | Nucleic Acids Res | 2003 | 12824425 | Yes |
1097 | 2086 | 2086.0 | 45.27 | 45.3 | Defensins: antimicrobial peptides of innate immunity. | Tomas Ganz | Nat Rev Immunol | 2003 | 12949495 | No |
1098 | 2086 | 2086.0 | 65.24 | 65.2 | Receiver operating characteristic curve in diagnostic test assessment. | Jayawant N Mandrekar | J Thorac Oncol | 2010 | 20736804 | No |
1099 | 8336 | 2084.0 | 302.66 | 75.7 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | J Clin Epidemiol | 2009 | 19631508 | No |
1100 | 2082 | 2082.0 | 53.0 | 53.0 | Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. | Gökhan S Hotamisligil | Cell | 2010 | 20303879 | No |
1101 | 2081 | 2081.0 | 39.94 | 39.9 | Method For Assay Of Intestinal Disaccharidases. | A Dahlqvist | Anal Biochem | 1964 | 14106916 | Yes |
1102 | 10395 | 2079.0 | 240.7 | 48.1 | Development and testing of a general amber force field. | Junmei Wang, Romain M Wolf, James W Caldwell, Peter A Kollman, David A Case | J Comput Chem | 2004 | 15116359 | Yes |
1103 | 4155 | 2077.5 | 81.89 | 40.9 | Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. | M Gossen, H Bujard | Proc Natl Acad Sci U S A | 1992 | 1319065 | Yes |
1104 | 2077 | 2077.0 | 71.87 | 71.9 | Purinergic nerves. | G Burnstock | Pharmacol Rev | 1972 | 4404211 | No |
1105 | 4153 | 2076.5 | 82.04 | 41.0 | Mammalian MAP kinase signalling cascades. | L Chang, M Karin | Nature | 2001 | 11242034 | No |
1106 | 8304 | 2076.0 | 272.74 | 68.2 | Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. | A J Hughes, S E Daniel, L Kilford, A J Lees | J Neurol Neurosurg Psychiatry | 1992 | 1564476 | Yes |
1107 | 2076 | 2076.0 | 52.78 | 52.8 | What is cognitive reserve? Theory and research application of the reserve concept. | Yaakov Stern | J Int Neuropsychol Soc | 2002 | 11939702 | No |
1108 | 4149 | 2074.5 | 35.9 | 17.9 | Genetic regulatory mechanisms in the synthesis of proteins. | F Jacob, J Monod | J Mol Biol | 1961 | 13718526 | Yes |
1109 | 4148 | 2074.0 | 80.83 | 40.4 | Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. | Rudolf Jaenisch, Adrian Bird | Nat Genet | 2003 | 12610534 | No |
1110 | 2073 | 2073.0 | 50.74 | 50.7 | Mechanisms of hepatic fibrogenesis. | Scott L Friedman | Gastroenterology | 2008 | 18471545 | No |
1111 | 4143 | 2071.5 | 126.19 | 63.1 | Polymyositis and dermatomyositis (first of two parts). | A Bohan, J B Peter | N Engl J Med | 1975 | 1090839 | No |
1112 | 2069 | 2069.0 | 59.89 | 59.9 | ATP-regulated K+ channels in cardiac muscle. | A Noma | Nature | 1983 | 6310409 | Yes |
1113 | 2067 | 2067.0 | 39.81 | 39.8 | Signalling pathways of the TNF superfamily: a double-edged sword. | Bharat B Aggarwal | Nat Rev Immunol | 2003 | 12949498 | No |
1114 | 2065 | 2065.0 | 41.43 | 41.4 | Metastasis to bone: causes, consequences and therapeutic opportunities. | Gregory R Mundy | Nat Rev Cancer | 2002 | 12154351 | No |
1115 | 2065 | 2065.0 | 37.76 | 37.8 | Enzymatic Basis For Active Transport Of Na+ And K+ Across Cell Membrane. | J C Skou | Physiol Rev | 1965 | 14337569 | No |
1116 | 2065 | 2065.0 | 60.82 | 60.8 | Global epidemiology of oral and oropharyngeal cancer. | Saman Warnakulasuriya | Oral Oncol | 2009 | 18804401 | No |
1117 | 4126 | 2063.0 | 86.02 | 43.0 | A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation. | G Shaw, R Kamen | Cell | 1986 | 3488815 | Yes |
1118 | 2062 | 2062.0 | 52.77 | 52.8 | The heme oxygenase system: a regulator of second messenger gases. | M D Maines | Annu Rev Pharmacol Toxicol | 1997 | 9131263 | No |
1119 | 6182 | 2060.7 | 202.57 | 67.5 | Parallel organization of functionally segregated circuits linking basal ganglia and cortex. | G E Alexander, M R DeLong, P L Strick | Annu Rev Neurosci | 1986 | 3085570 | No |
1120 | 2060 | 2060.0 | 42.6 | 42.6 | G1 events and regulation of cell proliferation. | A B Pardee | Science | 1989 | 2683075 | No |
1121 | 2057 | 2057.0 | 47.84 | 47.8 | Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. | Scott L Friedman | Physiol Rev | 2008 | 18195085 | No |
1122 | 4113 | 2056.5 | 177.8 | 88.9 | The Brief Symptom Inventory: an introductory report. | L R Derogatis, N Melisaratos | Psychol Med | 1983 | 6622612 | Yes |
1123 | 2056 | 2056.0 | 42.04 | 42.0 | Molecular bases for circadian clocks. | J C Dunlap | Cell | 1999 | 9988221 | No |
1124 | 4109 | 2054.5 | 101.39 | 50.7 | Cutaneous wound healing. | A J Singer, R A Clark | N Engl J Med | 1999 | 10471461 | No |
1125 | 4107 | 2053.5 | 0.0 | 0.0 | Plaque formation and isolation of pure lines with poliomyelitis viruses. | R Dulbecco, M Vogt | J Exp Med | 1954 | 13130792 | Yes |
1126 | 2053 | 2053.0 | 18.78 | 18.8 | The kinetics of enzyme-catalyzed reactions with two or more substrates or products. I. Nomenclature and rate equations. | W W Cleland | Biochim Biophys Acta | 1963 | 14021667 | Yes |
1127 | 4104 | 2052.0 | 0.0 | 0.0 | A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. | R F Beers, I W Sizer | J Biol Chem | 1952 | 14938361 | Yes |
1128 | 2051 | 2051.0 | 23.79 | 23.8 | Selection Of Hybrids From Matings Of Fibroblasts In Vitro And Their Presumed Recombinants. | J W Littlefield | Science | 1964 | 14168277 | Yes |
1129 | 2049 | 2049.0 | 47.8 | 47.8 | Interleukin-2: inception, impact, and implications. | K A Smith | Science | 1988 | 3131876 | No |
1130 | 6146 | 2048.7 | 165.56 | 55.2 | trimAl: a tool for automated alignment trimming in large-scale phylogenetic analyses. | Salvador Capella-Gutiérrez, José M Silla-Martínez, Toni Gabaldón | Bioinformatics | 2009 | 19505945 | Yes |
1131 | 6145 | 2048.3 | 198.12 | 66.0 | Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. | C Lord, M Rutter, A Le Couteur | J Autism Dev Disord | 1994 | 7814313 | Yes |
1132 | 2048 | 2048.0 | 120.44 | 120.4 | Understanding Bland Altman analysis. | Davide Giavarina | Biochem Med (Zagreb) | 2015 | 26110027 | No |
1133 | 4090 | 2045.0 | 98.28 | 49.1 | Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions. | M Nei, T Gojobori | Mol Biol Evol | 1986 | 3444411 | Yes |
1134 | 2045 | 2045.0 | 56.64 | 56.6 | Estimating causal effects from large data sets using propensity scores. | D B Rubin | Ann Intern Med | 1997 | 9382394 | No |
1135 | 4088 | 2044.0 | 110.46 | 55.2 | New perspectives in cell adhesion: RGD and integrins. | E Ruoslahti, M D Pierschbacher | Science | 1987 | 2821619 | No |
1136 | 4079 | 2039.5 | 104.2 | 52.1 | Building better batteries. | M Armand, J-M Tarascon | Nature | 2008 | 18256660 | No |
1137 | 2039 | 2039.0 | 61.2 | 61.2 | Loss, trauma, and human resilience: have we underestimated the human capacity to thrive after extremely aversive events? | George A Bonanno | Am Psychol | 2004 | 14736317 | No |
1138 | 2039 | 2039.0 | 44.65 | 44.6 | Gene finding in novel genomes. | Ian Korf | BMC Bioinformatics | 2004 | 15144565 | Yes |
1139 | 4076 | 2038.0 | 137.05 | 68.5 | PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data. | Daniel R Roe, Thomas E Cheatham | J Chem Theory Comput | 2013 | 26583988 | Yes |
1140 | 6113 | 2037.7 | 827.63 | 275.9 | MEGA11: Molecular Evolutionary Genetics Analysis Version 11. | Koichiro Tamura, Glen Stecher, Sudhir Kumar | Mol Biol Evol | 2021 | 33892491 | Yes |
1141 | 6106 | 2035.3 | 184.12 | 61.4 | Estimating the mean and variance from the median, range, and the size of a sample. | Stela Pudar Hozo, Benjamin Djulbegovic, Iztok Hozo | BMC Med Res Methodol | 2005 | 15840177 | Yes |
1142 | 2034 | 2034.0 | 80.47 | 80.5 | Perception of risk. | P Slovic | Science | 1987 | 3563507 | Yes |
1143 | 22370 | 2033.6 | 555.38 | 50.5 | PLINK: a tool set for whole-genome association and population-based linkage analyses. | Shaun Purcell, Benjamin Neale, Kathe Todd-Brown, Lori Thomas, Manuel A R Ferreira, David Bender, Julian Maller, Pamela Sklar, Paul I W de Bakker, Mark J Daly, Pak C Sham | Am J Hum Genet | 2007 | 17701901 | Yes |
1144 | 2033 | 2033.0 | 72.46 | 72.5 | Determination of glutathione and glutathione disulfide in biological samples. | M E Anderson | Methods Enzymol | 1985 | 4088074 | Yes |
1145 | 2033 | 2033.0 | 0.0 | 0.0 | On respiratory impairment in cancer cells. | O Warburg | Science | 1956 | 13351639 | Yes |
1146 | 4062 | 2031.0 | 98.35 | 49.2 | Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. | P Liang, A B Pardee | Science | 1992 | 1354393 | Yes |
1147 | 4062 | 2031.0 | 79.57 | 39.8 | The Wnt signaling pathway in development and disease. | Catriona Y Logan, Roel Nusse | Annu Rev Cell Dev Biol | 2004 | 15473860 | No |
1148 | 2030 | 2030.0 | 39.05 | 39.0 | CpG motifs in bacterial DNA and their immune effects. | Arthur M Krieg | Annu Rev Immunol | 2002 | 11861616 | No |
1149 | 2029 | 2029.0 | 47.67 | 47.7 | Calcium signaling. | D E Clapham | Cell | 1995 | 7834745 | No |
1150 | 8114 | 2028.5 | 305.03 | 76.3 | The Fagerström Test for Nicotine Dependence: a revision of the Fagerström Tolerance Questionnaire. | T F Heatherton, L T Kozlowski, R C Frecker, K O Fagerström | Br J Addict | 1991 | 1932883 | Yes |
1151 | 2026 | 2026.0 | 55.39 | 55.4 | Trail Making Test A and B: normative data stratified by age and education. | Tom N Tombaugh | Arch Clin Neuropsychol | 2004 | 15010086 | Yes |
1152 | 4051 | 2025.5 | 119.16 | 59.6 | Mechanisms of salinity tolerance. | Rana Munns, Mark Tester | Annu Rev Plant Biol | 2008 | 18444910 | No |
1153 | 12152 | 2025.3 | 374.61 | 62.4 | Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. | Jacques Ferlay, Hai-Rim Shin, Freddie Bray, David Forman, Colin Mathers, Donald Maxwell Parkin | Int J Cancer | 2010 | 21351269 | Yes |
1154 | 4050 | 2025.0 | 94.68 | 47.3 | Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. | B A Reynolds, S Weiss | Science | 1992 | 1553558 | Yes |
1155 | 2024 | 2024.0 | 61.96 | 62.0 | Ethical authorship and publishing. | Andrew J S Coats | Int J Cardiol | 2009 | 19046787 | No |
1156 | 4045 | 2022.5 | 120.21 | 60.1 | Individual differences in two emotion regulation processes: implications for affect, relationships, and well-being. | James J Gross, Oliver P John | J Pers Soc Psychol | 2003 | 12916575 | Yes |
1157 | 2022 | 2022.0 | 48.71 | 48.7 | Python: a programming language for software integration and development. | M F Sanner | J Mol Graph Model | 1999 | 10660911 | Yes |
1158 | 2022 | 2022.0 | 42.58 | 42.6 | Developmental regulation of the growth plate. | Henry M Kronenberg | Nature | 2003 | 12748651 | No |
1159 | 2022 | 2022.0 | 62.67 | 62.7 | A new automated colorimetric method for measuring total oxidant status. | Ozcan Erel | Clin Biochem | 2005 | 16214125 | Yes |
1160 | 2021 | 2021.0 | 52.51 | 52.5 | Analysis of bacteriophage T7 early RNAs and proteins on slab gels. | F W Studier | J Mol Biol | 1973 | 4760132 | Yes |
1161 | 8084 | 2021.0 | 329.37 | 82.3 | jModelTest 2: more models, new heuristics and parallel computing. | Diego Darriba, Guillermo L Taboada, Ramón Doallo, David Posada | Nat Methods | 2012 | 22847109 | Yes |
1162 | 2020 | 2020.0 | 38.94 | 38.9 | Antiviral actions of interferons. | C E Samuel | Clin Microbiol Rev | 2001 | 11585785 | No |
1163 | 6059 | 2019.7 | 228.35 | 76.1 | Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA. | G Muyzer, E C de Waal, A G Uitterlinden | Appl Environ Microbiol | 1993 | 7683183 | Yes |
1164 | 2019 | 2019.0 | 96.76 | 96.8 | Performance-oriented assessment of mobility problems in elderly patients. | M E Tinetti | J Am Geriatr Soc | 1986 | 3944402 | Yes |
1165 | 2019 | 2019.0 | 117.67 | 117.7 | Making sense of implementation theories, models and frameworks. | Per Nilsen | Implement Sci | 2015 | 25895742 | Yes |
1166 | 2016 | 2016.0 | 46.81 | 46.8 | DAMPs, PAMPs and alarmins: all we need to know about danger. | Marco E Bianchi | J Leukoc Biol | 2007 | 17032697 | No |
1167 | 8063 | 2015.8 | 195.32 | 48.8 | Cancer-related inflammation. | Alberto Mantovani, Paola Allavena, Antonio Sica, Frances Balkwill | Nature | 2008 | 18650914 | No |
1168 | 2014 | 2014.0 | 58.4 | 58.4 | Protein oxidation and aging. | E R Stadtman | Science | 1992 | 1355616 | No |
1169 | 2014 | 2014.0 | 97.41 | 97.4 | Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? | J V Neel | Am J Hum Genet | 1962 | 13937884 | Yes |
1170 | 2013 | 2013.0 | 43.93 | 43.9 | Biology of natural killer cells. | G Trinchieri | Adv Immunol | 1989 | 2683611 | No |
1171 | 2010 | 2010.0 | 83.7 | 83.7 | A rating scale for drug-induced akathisia. | T R Barnes | Br J Psychiatry | 1989 | 2574607 | Yes |
1172 | 8040 | 2010.0 | 263.18 | 65.8 | Antibiotic susceptibility testing by a standardized single disk method. | A W Bauer, W M Kirby, J C Sherris, M Turck | Am J Clin Pathol | 1966 | 5325707 | Yes |
1173 | 2010 | 2010.0 | 101.93 | 101.9 | Subjective well-being. | E Diener | Psychol Bull | 1984 | 6399758 | No |
1174 | 2009 | 2009.0 | 51.16 | 51.2 | Flow-mediated endothelial mechanotransduction. | P F Davies | Physiol Rev | 1995 | 7624393 | No |
1175 | 2009 | 2009.0 | 56.15 | 56.1 | Flavonoids as antioxidants. | P G Pietta | J Nat Prod | 2000 | 10924197 | No |
1176 | 2009 | 2009.0 | 43.6 | 43.6 | Neutrophils and immunity: challenges and opportunities. | Carl Nathan | Nat Rev Immunol | 2006 | 16498448 | No |
1177 | 2009 | 2009.0 | 0.0 | 0.0 | Antigen-antibody reactions in gels. | O Ouchterlony | Acta Pathol Microbiol Scand | 1949 | 18143039 | Yes |
1178 | 2008 | 2008.0 | 41.55 | 41.5 | XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density. | D E McRee | J Struct Biol | 1999 | 10222271 | Yes |
1179 | 2008 | 2008.0 | 39.59 | 39.6 | DNA topoisomerases: structure, function, and mechanism. | J J Champoux | Annu Rev Biochem | 2001 | 11395412 | No |
1180 | 2007 | 2007.0 | 34.6 | 34.6 | ATM and related protein kinases: safeguarding genome integrity. | Yosef Shiloh | Nat Rev Cancer | 2003 | 12612651 | No |
1181 | 2007 | 2007.0 | 68.23 | 68.2 | The emerging role of lncRNAs in cancer. | Maite Huarte | Nat Med | 2015 | 26540387 | No |
1182 | 14035 | 2005.0 | 308.41 | 44.1 | Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. | Jo Vandesompele, Katleen De Preter, Filip Pattyn, Bruce Poppe, Nadine Van Roy, Anne De Paepe, Frank Speleman | Genome Biol | 2002 | 12184808 | Yes |
1183 | 4010 | 2005.0 | 88.3 | 44.1 | The DNA-damage response in human biology and disease. | Stephen P Jackson, Jiri Bartek | Nature | 2009 | 19847258 | No |
1184 | 2004 | 2004.0 | 36.71 | 36.7 | In situ hybridization: an improved whole-mount method for Xenopus embryos. | R M Harland | Methods Cell Biol | 1991 | 1811161 | Yes |
1185 | 2003 | 2003.0 | 55.15 | 55.1 | Determination of minimum inhibitory concentrations. | J M Andrews | J Antimicrob Chemother | 2001 | 11420333 | Yes |
1186 | 2000 | 2000.0 | 39.4 | 39.4 | DNA methylation and human disease. | Keith D Robertson | Nat Rev Genet | 2005 | 16136652 | No |
1187 | 1999 | 1999.0 | 43.76 | 43.8 | Structural design and molecular evolution of a cytokine receptor superfamily. | J F Bazan | Proc Natl Acad Sci U S A | 1990 | 2169613 | Yes |
1188 | 3998 | 1999.0 | 91.52 | 45.8 | Base-calling of automated sequencer traces using phred. II. Error probabilities. | B Ewing, P Green | Genome Res | 1998 | 9521922 | Yes |
1189 | 3996 | 1998.0 | 138.26 | 69.1 | Reactive oxygen species and antioxidant machinery in abiotic stress tolerance in crop plants. | Sarvajeet Singh Gill, Narendra Tuteja | Plant Physiol Biochem | 2010 | 20870416 | No |
1190 | 3995 | 1997.5 | 142.88 | 71.4 | ITS primers with enhanced specificity for basidiomycetes--application to the identification of mycorrhizae and rusts. | M Gardes, T D Bruns | Mol Ecol | 1993 | 8180733 | Yes |
1191 | 3993 | 1996.5 | 90.17 | 45.1 | Liver fibrosis. | Ramón Bataller, David A Brenner | J Clin Invest | 2005 | 15690074 | No |
1192 | 1996 | 1996.0 | 50.32 | 50.3 | Determination and analysis of urea and guanidine hydrochloride denaturation curves. | C N Pace | Methods Enzymol | 1986 | 3773761 | Yes |
1193 | 1996 | 1996.0 | 48.6 | 48.6 | Negative refraction makes a perfect lens | J B Pendry | Phys Rev Lett | 2000 | 11041972 | Yes |
1194 | 1996 | 1996.0 | 41.59 | 41.6 | TRP channels as cellular sensors. | David E Clapham | Nature | 2003 | 14654832 | No |
1195 | 1995 | 1995.0 | 62.82 | 62.8 | Health consequences of intimate partner violence. | Jacquelyn C Campbell | Lancet | 2002 | 11965295 | No |
1196 | 1993 | 1993.0 | 38.79 | 38.8 | Approaching the asymptote? Evolution and revolution in immunology. | C A Janeway | Cold Spring Harb Symp Quant Biol | 1989 | 2700931 | No |
1197 | 1992 | 1992.0 | 66.13 | 66.1 | The use of a plus-maze to measure anxiety in the mouse. | R G Lister | Psychopharmacology (Berl) | 1987 | 3110839 | Yes |
1198 | 3984 | 1992.0 | 89.87 | 44.9 | The acute respiratory distress syndrome. | L B Ware, M A Matthay | N Engl J Med | 2000 | 10793167 | No |
1199 | 3984 | 1992.0 | 88.11 | 44.1 | Issues and challenges facing rechargeable lithium batteries. | J M Tarascon, M Armand | Nature | 2001 | 11713543 | Yes |
1200 | 1992 | 1992.0 | 70.34 | 70.3 | Pro-resolving lipid mediators are leads for resolution physiology. | Charles N Serhan | Nature | 2014 | 24899309 | No |
1201 | 1991 | 1991.0 | 43.85 | 43.9 | The fractionation of high-molecular-weight ribonucleic acid by polyacrylamide-gel electrophoresis. | U E Loening | Biochem J | 1967 | 5339944 | Yes |
1202 | 3981 | 1990.5 | 85.57 | 42.8 | Lessons from hereditary colorectal cancer. | K W Kinzler, B Vogelstein | Cell | 1996 | 8861899 | No |
1203 | 1990 | 1990.0 | 54.81 | 54.8 | The biology of interleukin-6. | T Kishimoto | Blood | 1989 | 2473791 | No |
1204 | 1989 | 1989.0 | 47.59 | 47.6 | Interfaces and the driving force of hydrophobic assembly. | David Chandler | Nature | 2005 | 16193038 | No |
1205 | 13909 | 1987.0 | 316.79 | 45.3 | Induction of pluripotent stem cells from adult human fibroblasts by defined factors. | Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda, Shinya Yamanaka | Cell | 2007 | 18035408 | Yes |
1206 | 3973 | 1986.5 | 86.32 | 43.2 | The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. | A J Ridley, A Hall | Cell | 1992 | 1643657 | Yes |
1207 | 1985 | 1985.0 | 40.63 | 40.6 | Mechanisms of intracellular protein transport. | J E Rothman | Nature | 1994 | 7969419 | No |
1208 | 1985 | 1985.0 | 62.74 | 62.7 | Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. | Sergio Pecorelli | Int J Gynaecol Obstet | 2009 | 19367689 | No |
1209 | 1984 | 1984.0 | 37.77 | 37.8 | Notch signalling: a simple pathway becomes complex. | Sarah J Bray | Nat Rev Mol Cell Biol | 2006 | 16921404 | No |
1210 | 1984 | 1984.0 | 48.43 | 48.4 | Pathogen recognition and inflammatory signaling in innate immune defenses. | Trine H Mogensen | Clin Microbiol Rev | 2009 | 19366914 | No |
1211 | 3958 | 1979.0 | 110.69 | 55.3 | Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. | B J Marshall, J R Warren | Lancet | 1984 | 6145023 | Yes |
1212 | 3957 | 1978.5 | 98.15 | 49.1 | Leptin and the regulation of body weight in mammals. | J M Friedman, J L Halaas | Nature | 1998 | 9796811 | No |
1213 | 1978 | 1978.0 | 49.26 | 49.3 | Hydrogels for biomedical applications. | Allan S Hoffman | Adv Drug Deliv Rev | 2002 | 11755703 | No |
1214 | 1977 | 1977.0 | 60.51 | 60.5 | Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders. | Berislav V Zlokovic | Nat Rev Neurosci | 2011 | 22048062 | No |
1215 | 1976 | 1976.0 | 63.06 | 63.1 | Grounded cognition. | Lawrence W Barsalou | Annu Rev Psychol | 2008 | 17705682 | No |
1216 | 3946 | 1973.0 | 108.35 | 54.2 | Insulin-like growth factors and their binding proteins: biological actions. | J I Jones, D R Clemmons | Endocr Rev | 1995 | 7758431 | No |
1217 | 1972 | 1972.0 | 62.57 | 62.6 | Calculation of substrate oxidation rates in vivo from gaseous exchange. | K N Frayn | J Appl Physiol Respir Environ Exerc Physiol | 1983 | 6618956 | Yes |
1218 | 1972 | 1972.0 | 119.61 | 119.6 | The Global Epidemic of the Metabolic Syndrome. | Mohammad G Saklayen | Curr Hypertens Rep | 2018 | 29480368 | No |
1219 | 5913 | 1971.0 | 192.11 | 64.0 | AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. | P G Reeves, F H Nielsen, G C Fahey | J Nutr | 1993 | 8229312 | No |
1220 | 1970 | 1970.0 | 52.62 | 52.6 | Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis. | J Folkman | N Engl J Med | 1995 | 7491141 | No |
1221 | 1970 | 1970.0 | 61.65 | 61.6 | Epidemiological features of chronic low-back pain. | G B Andersson | Lancet | 1999 | 10470716 | No |
1222 | 3938 | 1969.0 | 122.14 | 61.1 | Photoperoxidation in isolated chloroplasts. I. Kinetics and stoichiometry of fatty acid peroxidation. | R L Heath, L Packer | Arch Biochem Biophys | 1968 | 5655425 | Yes |
1223 | 1968 | 1968.0 | 0.0 | 0.0 | Crystalline Soybean Trypsin Inhibitor : Ii. General Properties. | M Kunitz | J Gen Physiol | 1947 | 19873496 | Yes |
1224 | 1965 | 1965.0 | 86.74 | 86.7 | A modified card sorting test sensitive to frontal lobe defects. | H E Nelson | Cortex | 1976 | 1009768 | Yes |
1225 | 1965 | 1965.0 | 45.28 | 45.3 | Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. | B L Wajchenberg | Endocr Rev | 2000 | 11133069 | No |
1226 | 1964 | 1964.0 | 34.72 | 34.7 | Signaling--2000 and beyond. | T Hunter | Cell | 2000 | 10647936 | No |
1227 | 1964 | 1964.0 | 41.15 | 41.1 | The immunopathogenesis of sepsis. | Jonathan Cohen | Nature | 2002 | 12490963 | No |
1228 | 3924 | 1962.0 | 96.44 | 48.2 | Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. | P J Barnes, M Karin | N Engl J Med | 1997 | 9091804 | No |
1229 | 1962 | 1962.0 | 45.8 | 45.8 | The global health burden of infection-associated cancers in the year 2002. | Donald Maxwell Parkin | Int J Cancer | 2006 | 16404738 | Yes |
1230 | 5885 | 1961.7 | 170.46 | 56.8 | Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration. | Helga Thorvaldsdóttir, James T Robinson, Jill P Mesirov | Brief Bioinform | 2013 | 22517427 | Yes |
1231 | 1961 | 1961.0 | 34.12 | 34.1 | Mechanisms of alternative pre-messenger RNA splicing. | Douglas L Black | Annu Rev Biochem | 2003 | 12626338 | No |
1232 | 1961 | 1961.0 | 0.0 | 0.0 | Dendritic organization in the neurons of the visual and motor cortices of the cat. | D A Sholl | J Anat | 1953 | 13117757 | Yes |
1233 | 3918 | 1959.0 | 125.8 | 62.9 | Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid. | A C Chang, S N Cohen | J Bacteriol | 1978 | 149110 | Yes |
1234 | 1959 | 1959.0 | 57.88 | 57.9 | Intracellular calcium homeostasis. | E Carafoli | Annu Rev Biochem | 1987 | 3304139 | No |
1235 | 3917 | 1958.5 | 132.78 | 66.4 | Mathematical model for studying genetic variation in terms of restriction endonucleases. | M Nei, W H Li | Proc Natl Acad Sci U S A | 1979 | 291943 | Yes |
1236 | 3917 | 1958.5 | 122.96 | 61.5 | Understanding interobserver agreement: the kappa statistic. | Anthony J Viera, Joanne M Garrett | Fam Med | 2005 | 15883903 | Yes |
1237 | 1958 | 1958.0 | 40.63 | 40.6 | Maintenance of C. elegans. | Theresa Stiernagle | WormBook | 2006 | 18050451 | No |
1238 | 1957 | 1957.0 | 61.71 | 61.7 | Sick individuals and sick populations. | G Rose | Int J Epidemiol | 1985 | 3872850 | Yes |
1239 | 1955 | 1955.0 | 39.51 | 39.5 | The expanding role of mitochondria in apoptosis. | X Wang | Genes Dev | 2001 | 11711427 | No |
1240 | 3909 | 1954.5 | 59.31 | 29.7 | Preparation Of Fatty Acid Methyl Esters And Dimethylacetals From Lipids With Boron Fluoride--Methanol. | W R Morrison, L M Smith | J Lipid Res | 1964 | 14221106 | Yes |
1241 | 1953 | 1953.0 | 62.74 | 62.7 | The Gingival Index, the Plaque Index and the Retention Index Systems. | H Löe | J Periodontol | 1967 | 5237684 | Yes |
1242 | 1953 | 1953.0 | 0.0 | 0.0 | Influences of glucose loading and of injected insulin on hepatic glucose output. | R Steele | Ann N Y Acad Sci | 1959 | 13833973 | Yes |
1243 | 1953 | 1953.0 | 39.04 | 39.0 | The complex language of chromatin regulation during transcription. | Shelley L Berger | Nature | 2007 | 17522673 | No |
1244 | 1952 | 1952.0 | 37.58 | 37.6 | Systems biology: a brief overview. | Hiroaki Kitano | Science | 2002 | 11872829 | No |
1245 | 3902 | 1951.0 | 92.5 | 46.2 | Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. | J G Rheinwald, H Green | Cell | 1975 | 1052771 | Yes |
1246 | 15601 | 1950.1 | 644.93 | 80.6 | The SILVA ribosomal RNA gene database project: improved data processing and web-based tools. | Christian Quast, Elmar Pruesse, Pelin Yilmaz, Jan Gerken, Timmy Schweer, Pablo Yarza, Jörg Peplies, Frank Oliver Glöckner | Nucleic Acids Res | 2013 | 23193283 | Yes |
1247 | 5850 | 1950.0 | 107.06 | 35.7 | Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. | Jason D Fontenot, Marc A Gavin, Alexander Y Rudensky | Nat Immunol | 2003 | 12612578 | Yes |
1248 | 7796 | 1949.0 | 188.26 | 47.1 | Improved optimization for the robust and accurate linear registration and motion correction of brain images. | Mark Jenkinson, Peter Bannister, Michael Brady, Stephen Smith | Neuroimage | 2002 | 12377157 | Yes |
1249 | 1946 | 1946.0 | 79.1 | 79.1 | Specific pharmacology of calcium in myocardium, cardiac pacemakers, and vascular smooth muscle. | A Fleckenstein | Annu Rev Pharmacol Toxicol | 1977 | 326161 | No |
1250 | 1946 | 1946.0 | 50.11 | 50.1 | Dengue and dengue hemorrhagic fever. | D J Gubler | Clin Microbiol Rev | 1998 | 9665979 | No |
1251 | 3891 | 1945.5 | 65.19 | 32.6 | Periodate-lysine-paraformaldehyde fixative. A new fixation for immunoelectron microscopy. | I W McLean, P K Nakane | J Histochem Cytochem | 1974 | 4374474 | Yes |
1252 | 3891 | 1945.5 | 90.78 | 45.4 | Neuronal oscillations in cortical networks. | György Buzsáki, Andreas Draguhn | Science | 2004 | 15218136 | No |
1253 | 1944 | 1944.0 | 0.0 | 0.0 | On estimating the relation between blood group and disease. | B Woolf | Ann Hum Genet | 1955 | 14388528 | Yes |
1254 | 5828 | 1942.7 | 120.01 | 40.0 | Rapid and efficient site-specific mutagenesis without phenotypic selection. | T A Kunkel, J D Roberts, R A Zakour | Methods Enzymol | 1987 | 3323813 | Yes |
1255 | 1941 | 1941.0 | 39.73 | 39.7 | Thrombin signalling and protease-activated receptors. | S R Coughlin | Nature | 2000 | 11001069 | No |
1256 | 1940 | 1940.0 | 40.15 | 40.1 | Thickness, cross-sectional areas and depth of invasion in the prognosis of cutaneous melanoma. | A Breslow | Ann Surg | 1970 | 5477666 | Yes |
1257 | 1940 | 1940.0 | 0.0 | 0.0 | The adsorption of proteins on erythrocytes treated with tannic acid and subsequent hemagglutination by antiprotein sera. | S V Boyden | J Exp Med | 1951 | 14803635 | Yes |
1258 | 1940 | 1940.0 | 44.79 | 44.8 | The retinal pigment epithelium in visual function. | Olaf Strauss | Physiol Rev | 2005 | 15987797 | No |
1259 | 1939 | 1939.0 | 23.28 | 23.3 | A theory of cerebellar cortex. | D Marr | J Physiol | 1969 | 5784296 | Yes |
1260 | 1936 | 1936.0 | 64.37 | 64.4 | Intermediate filaments as mechanical integrators of cellular space. | E Lazarides | Nature | 1980 | 7188712 | Yes |
1261 | 1936 | 1936.0 | 42.24 | 42.2 | The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. | Michael R Lieber | Annu Rev Biochem | 2010 | 20192759 | No |
1262 | 1935 | 1935.0 | 41.91 | 41.9 | A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics. | J SantaLucia | Proc Natl Acad Sci U S A | 1998 | 9465037 | Yes |
1263 | 1935 | 1935.0 | 46.67 | 46.7 | Episodic memory: from mind to brain. | Endel Tulving | Annu Rev Psychol | 2002 | 11752477 | Yes |
1264 | 1934 | 1934.0 | 58.72 | 58.7 | Matching methods for causal inference: A review and a look forward. | Elizabeth A Stuart | Stat Sci | 2010 | 20871802 | Yes |
1265 | 1933 | 1933.0 | 55.27 | 55.3 | Excitotoxic cell death. | D W Choi | J Neurobiol | 1992 | 1361523 | No |
1266 | 1932 | 1932.0 | 57.6 | 57.6 | Calbindin D-28k and parvalbumin in the rat nervous system. | M R Celio | Neuroscience | 1990 | 2199841 | Yes |
1267 | 3864 | 1932.0 | 158.09 | 79.0 | Cancer immunotherapy using checkpoint blockade. | Antoni Ribas, Jedd D Wolchok | Science | 2018 | 29567705 | No |
1268 | 1931 | 1931.0 | 60.47 | 60.5 | Fluorographic detection of radioactivity in polyacrylamide gels with the water-soluble fluor, sodium salicylate. | J P Chamberlain | Anal Biochem | 1979 | 543547 | Yes |
1269 | 1931 | 1931.0 | 47.99 | 48.0 | High-speed scanning in human memory. | S Sternberg | Science | 1966 | 5939936 | Yes |
1270 | 1929 | 1929.0 | 42.8 | 42.8 | Signal sequences. The limits of variation. | G von Heijne | J Mol Biol | 1985 | 4032478 | Yes |
1271 | 3857 | 1928.5 | 73.69 | 36.8 | Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. | M Karin, Y Ben-Neriah | Annu Rev Immunol | 2000 | 10837071 | No |
1272 | 1928 | 1928.0 | 50.66 | 50.7 | DNA topoisomerase poisons as antitumor drugs. | L F Liu | Annu Rev Biochem | 1989 | 2549853 | No |
1273 | 1928 | 1928.0 | 75.09 | 75.1 | Predicting basal metabolic rate, new standards and review of previous work. | W N Schofield | Hum Nutr Clin Nutr | 1985 | 4044297 | Yes |
1274 | 5782 | 1927.3 | 190.99 | 63.7 | Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction data. | L Excoffier, P E Smouse, J M Quattro | Genetics | 1992 | 1644282 | Yes |
1275 | 1927 | 1927.0 | 70.54 | 70.5 | Cognitive reserve in ageing and Alzheimer's disease. | Yaakov Stern | Lancet Neurol | 2012 | 23079557 | No |
1276 | 3852 | 1926.0 | 122.04 | 61.0 | Oxygen toxicity, oxygen radicals, transition metals and disease. | B Halliwell, J M Gutteridge | Biochem J | 1984 | 6326753 | No |
1277 | 3850 | 1925.0 | 94.31 | 47.2 | The endophenotype concept in psychiatry: etymology and strategic intentions. | Irving I Gottesman, Todd D Gould | Am J Psychiatry | 2003 | 12668349 | No |
1278 | 3849 | 1924.5 | 102.66 | 51.3 | Inositol phosphates and cell signalling. | M J Berridge, R F Irvine | Nature | 1989 | 2550825 | No |
1279 | 3849 | 1924.5 | 130.72 | 65.4 | Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. | M H Zweig, G Campbell | Clin Chem | 1993 | 8472349 | No |
1280 | 1924 | 1924.0 | 53.68 | 53.7 | Cell biology and molecular basis of denitrification. | W G Zumft | Microbiol Mol Biol Rev | 1997 | 9409151 | No |
1281 | 1924 | 1924.0 | 39.18 | 39.2 | Mechanisms of cancer drug resistance. | Michael M Gottesman | Annu Rev Med | 2002 | 11818492 | No |
1282 | 1922 | 1922.0 | 83.58 | 83.6 | Brain dopamine receptors. | P Seeman | Pharmacol Rev | 1980 | 6117090 | No |
1283 | 3841 | 1920.5 | 154.44 | 77.2 | mTOR Signaling in Growth, Metabolism, and Disease. | Robert A Saxton, David M Sabatini | Cell | 2017 | 28283069 | No |
1284 | 3840 | 1920.0 | 138.16 | 69.1 | Pain assessment: global use of the Brief Pain Inventory. | C S Cleeland, K M Ryan | Ann Acad Med Singap | 1994 | 8080219 | No |
1285 | 1920 | 1920.0 | 33.83 | 33.8 | The regulation of E2F by pRB-family proteins. | N Dyson | Genes Dev | 1998 | 9694791 | No |
1286 | 3839 | 1919.5 | 85.07 | 42.5 | Parkinson's disease: mechanisms and models. | William Dauer, Serge Przedborski | Neuron | 2003 | 12971891 | No |
1287 | 1919 | 1919.0 | 45.56 | 45.6 | The genetics of ageing. | Cynthia J Kenyon | Nature | 2010 | 20336132 | No |
1288 | 1918 | 1918.0 | 63.03 | 63.0 | Physiological actions of taurine. | R J Huxtable | Physiol Rev | 1992 | 1731369 | No |
1289 | 1918 | 1918.0 | 43.11 | 43.1 | Targeting PI3K signalling in cancer: opportunities, challenges and limitations. | Jeffrey A Engelman | Nat Rev Cancer | 2009 | 19629070 | No |
1290 | 3835 | 1917.5 | 115.41 | 57.7 | Threshold-free cluster enhancement: addressing problems of smoothing, threshold dependence and localisation in cluster inference. | Stephen M Smith, Thomas E Nichols | Neuroimage | 2009 | 18501637 | Yes |
1291 | 3835 | 1917.5 | 130.66 | 65.3 | Regulation of microRNA biogenesis. | Minju Ha, V Narry Kim | Nat Rev Mol Cell Biol | 2014 | 25027649 | No |
1292 | 1917 | 1917.0 | 46.94 | 46.9 | DNA topoisomerases. | J C Wang | Annu Rev Biochem | 1985 | 2992360 | No |
1293 | 3834 | 1917.0 | 98.85 | 49.4 | Probing Single Molecules and Single Nanoparticles by Surface-Enhanced Raman Scattering | S Nie, S R Emory | Science | 1997 | 9027306 | Yes |
1294 | 7668 | 1917.0 | 185.82 | 46.5 | Epithelial-mesenchymal transitions in development and disease. | Jean Paul Thiery, Hervé Acloque, Ruby Y J Huang, M Angela Nieto | Cell | 2009 | 19945376 | No |
1295 | 1916 | 1916.0 | 56.34 | 56.3 | Inhibited spontaneous emission in solid-state physics and electronics. | E Yablonovitch | Phys Rev Lett | 1987 | 10034639 | Yes |
1296 | 3832 | 1916.0 | 0.0 | 0.0 | Acetylornithinase of Escherichia coli: partial purification and some properties. | H J Vogel, D M Bonner | J Biol Chem | 1956 | 13278318 | Yes |
1297 | 1916 | 1916.0 | 46.18 | 46.2 | Cancer chemoprevention with dietary phytochemicals. | Young-Joon Surh | Nat Rev Cancer | 2003 | 14570043 | No |
1298 | 5747 | 1915.7 | 198.42 | 66.1 | Molecular mechanisms of epithelial-mesenchymal transition. | Samy Lamouille, Jian Xu, Rik Derynck | Nat Rev Mol Cell Biol | 2014 | 24556840 | No |
1299 | 1915 | 1915.0 | 54.82 | 54.8 | The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. | G P Chrousos | N Engl J Med | 1995 | 7715646 | No |
1300 | 1914 | 1914.0 | 39.97 | 40.0 | A cell culture model for T lymphocyte clonal anergy. | R H Schwartz | Science | 1990 | 2113314 | Yes |
1301 | 3827 | 1913.5 | 105.87 | 52.9 | EQ-5D: a measure of health status from the EuroQol Group. | R Rabin, F de Charro | Ann Med | 2001 | 11491192 | No |
1302 | 1913 | 1913.0 | 44.81 | 44.8 | The dawning era of polymer therapeutics. | Ruth Duncan | Nat Rev Drug Discov | 2003 | 12750738 | No |
1303 | 7651 | 1912.8 | 188.38 | 47.1 | p53 mutations in human cancers. | M Hollstein, D Sidransky, B Vogelstein, C C Harris | Science | 1991 | 1905840 | No |
1304 | 7648 | 1912.0 | 298.09 | 74.5 | A simple technique for quantitation of low levels of DNA damage in individual cells. | N P Singh, M T McCoy, R R Tice, E L Schneider | Exp Cell Res | 1988 | 3345800 | Yes |
1305 | 1911 | 1911.0 | 51.36 | 51.4 | Systemic lupus erythematosus. | George C Tsokos | N Engl J Med | 2011 | 22129255 | No |
1306 | 1910 | 1910.0 | 53.8 | 53.8 | Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis. | A Dunaif | Endocr Rev | 1997 | 9408743 | No |
1307 | 1909 | 1909.0 | 53.42 | 53.4 | Introduction and General Overview of Cyclodextrin Chemistry. | József Szejtli | Chem Rev | 1998 | 11848947 | Yes |
1308 | 1908 | 1908.0 | 46.23 | 46.2 | Thioredoxin. | A Holmgren | Annu Rev Biochem | 1985 | 3896121 | No |
1309 | 3811 | 1905.5 | 138.51 | 69.3 | The need to belong: desire for interpersonal attachments as a fundamental human motivation. | R F Baumeister, M R Leary | Psychol Bull | 1995 | 7777651 | No |
1310 | 1905 | 1905.0 | 53.83 | 53.8 | In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain. | T R Chen | Exp Cell Res | 1977 | 65285 | Yes |
1311 | 5715 | 1905.0 | 145.29 | 48.4 | Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. | G S Hotamisligil, N S Shargill, B M Spiegelman | Science | 1993 | 7678183 | Yes |
1312 | 1901 | 1901.0 | 62.8 | 62.8 | The molecular theory of polyelectrolyte solutions with applications to the electrostatic properties of polynucleotides. | G S Manning | Q Rev Biophys | 1978 | 353876 | No |
1313 | 1900 | 1900.0 | 0.0 | 0.0 | The oxidation of ribonuclease with performic acid. | C H Hirs | J Biol Chem | 1956 | 13319283 | Yes |
1314 | 3797 | 1898.5 | 107.89 | 53.9 | Event-related EEG/MEG synchronization and desynchronization: basic principles. | G Pfurtscheller, F H Lopes da Silva | Clin Neurophysiol | 1999 | 10576479 | No |
1315 | 3794 | 1897.0 | 330.43 | 165.2 | WHO Declares COVID-19 a Pandemic. | Domenico Cucinotta, Maurizio Vanelli | Acta Biomed | 2020 | 32191675 | Yes |
1316 | 1896 | 1896.0 | 65.3 | 65.3 | Guided Search 2.0 A revised model of visual search. | J M Wolfe | Psychon Bull Rev | 1994 | 24203471 | Yes |
1317 | 5684 | 1894.7 | 341.67 | 113.9 | Research diagnostic criteria: rationale and reliability. | R L Spitzer, J Endicott, E Robins | Arch Gen Psychiatry | 1978 | 655775 | Yes |
1318 | 1894 | 1894.0 | 50.06 | 50.1 | Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic. | Robert E Marx | J Oral Maxillofac Surg | 2003 | 12966493 | Yes |
1319 | 1893 | 1893.0 | 69.36 | 69.4 | Recognition-by-components: a theory of human image understanding. | Irving Biederman | Psychol Rev | 1987 | 3575582 | Yes |
1320 | 1893 | 1893.0 | 55.36 | 55.4 | phangorn: phylogenetic analysis in R. | Klaus Peter Schliep | Bioinformatics | 2011 | 21169378 | Yes |
1321 | 1892 | 1892.0 | 41.04 | 41.0 | The mitogen-activated protein kinase signal transduction pathway. | R J Davis | J Biol Chem | 1993 | 8325833 | No |
1322 | 1892 | 1892.0 | 45.49 | 45.5 | The hydrogen bond in the solid state. | Thomas Steiner | Angew Chem Int Ed Engl | 2002 | 12491444 | Yes |
1323 | 1892 | 1892.0 | 40.37 | 40.4 | The etiology of chondromalacia patellae. | R E Outerbridge | J Bone Joint Surg Br | 1961 | 14038135 | Yes |
1324 | 3783 | 1891.5 | 84.93 | 42.5 | Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. | T Miyashita, J C Reed | Cell | 1995 | 7834749 | Yes |
1325 | 1891 | 1891.0 | 48.35 | 48.4 | From sensation to cognition. | M M Mesulam | Brain | 1998 | 9648540 | No |
1326 | 3780 | 1890.0 | 68.57 | 34.3 | Rho GTPases in cell biology. | Sandrine Etienne-Manneville, Alan Hall | Nature | 2002 | 12478284 | No |
1327 | 1889 | 1889.0 | 16.07 | 16.1 | Positional information and the spatial pattern of cellular differentiation. | L Wolpert | J Theor Biol | 1969 | 4390734 | Yes |
1328 | 5666 | 1888.7 | 238.39 | 79.5 | The behaviour change wheel: a new method for characterising and designing behaviour change interventions. | Susan Michie, Maartje M van Stralen, Robert West | Implement Sci | 2011 | 21513547 | No |
1329 | 3776 | 1888.0 | 117.65 | 58.8 | Efficient pseudopotentials for plane-wave calculations. | N Troullier, J L Martins | Phys Rev B Condens Matter | 1991 | 9997467 | Yes |
1330 | 1888 | 1888.0 | 41.22 | 41.2 | Cellular mechanisms of insulin resistance. | G I Shulman | J Clin Invest | 2000 | 10903330 | No |
1331 | 1887 | 1887.0 | 60.16 | 60.2 | Complete nucleotide sequence of the Escherichia coli plasmid pBR322. | J G Sutcliffe | Cold Spring Harb Symp Quant Biol | 1979 | 383387 | Yes |
1332 | 1886 | 1886.0 | 79.41 | 79.4 | The drug abuse screening test. | H A Skinner | Addict Behav | 1982 | 7183189 | Yes |
1333 | 7539 | 1884.8 | 252.4 | 63.1 | Reporting results of cancer treatment. | A B Miller, B Hoogstraten, M Staquet, A Winkler | Cancer | 1981 | 7459811 | Yes |
1334 | 3769 | 1884.5 | 112.69 | 56.3 | An efficient mRNA-dependent translation system from reticulocyte lysates. | H R Pelham, R J Jackson | Eur J Biochem | 1976 | 823012 | Yes |
1335 | 15065 | 1883.1 | 367.35 | 45.9 | Electric field effect in atomically thin carbon films. | K S Novoselov, A K Geim, S V Morozov, D Jiang, Y Zhang, S V Dubonos, I V Grigorieva, A A Firsov | Science | 2004 | 15499015 | Yes |
1336 | 1883 | 1883.0 | 53.68 | 53.7 | Multiple imputation: a primer. | J L Schafer | Stat Methods Med Res | 1999 | 10347857 | No |
1337 | 9407 | 1881.4 | 221.88 | 44.4 | Mapping and quantifying mammalian transcriptomes by RNA-Seq. | Ali Mortazavi, Brian A Williams, Kenneth McCue, Lorian Schaeffer, Barbara Wold | Nat Methods | 2008 | 18516045 | Yes |
1338 | 1881 | 1881.0 | 40.15 | 40.1 | Exploring complex networks. | S H Strogatz | Nature | 2001 | 11258382 | No |
1339 | 3761 | 1880.5 | 78.77 | 39.4 | Monocyte and macrophage heterogeneity. | Siamon Gordon, Philip R Taylor | Nat Rev Immunol | 2005 | 16322748 | No |
1340 | 3760 | 1880.0 | 143.74 | 71.9 | ROS function in redox signaling and oxidative stress. | Michael Schieber, Navdeep S Chandel | Curr Biol | 2014 | 24845678 | No |
1341 | 1879 | 1879.0 | 68.79 | 68.8 | Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury. | D R Janero | Free Radic Biol Med | 1990 | 2079232 | No |
1342 | 3758 | 1879.0 | 86.1 | 43.0 | The Fas death factor. | S Nagata, P Golstein | Science | 1995 | 7533326 | No |
1343 | 1878 | 1878.0 | 44.67 | 44.7 | Integration, scaling, space-group assignment and post-refinement. | Wolfgang Kabsch | Acta Crystallogr D Biol Crystallogr | 2010 | 20124693 | Yes |
1344 | 3754 | 1877.0 | 89.5 | 44.8 | The future of genetic studies of complex human diseases. | N Risch, K Merikangas | Science | 1996 | 8801636 | Yes |
1345 | 1876 | 1876.0 | 49.07 | 49.1 | Molecular dissection of reactive astrogliosis and glial scar formation. | Michael V Sofroniew | Trends Neurosci | 2009 | 19782411 | No |
1346 | 1875 | 1875.0 | 42.05 | 42.0 | Integrating cell-signalling pathways with NF-kappaB and IKK function. | Neil D Perkins | Nat Rev Mol Cell Biol | 2007 | 17183360 | No |
1347 | 1875 | 1875.0 | 60.19 | 60.2 | Cognitive reserve. | Yaakov Stern | Neuropsychologia | 2009 | 19467352 | No |
1348 | 1874 | 1874.0 | 86.26 | 86.3 | A simple fluorometric assay for lipoperoxide in blood plasma. | K Yagi | Biochem Med | 1976 | 962904 | Yes |
1349 | 3748 | 1874.0 | 77.82 | 38.9 | Identification of common molecular subsequences. | T F Smith, M S Waterman | J Mol Biol | 1981 | 7265238 | Yes |
1350 | 3745 | 1872.5 | 125.82 | 62.9 | Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. | G Di Chiara, A Imperato | Proc Natl Acad Sci U S A | 1988 | 2899326 | Yes |
1351 | 1872 | 1872.0 | 50.94 | 50.9 | A computational procedure for determining energetically favorable binding sites on biologically important macromolecules. | P J Goodford | J Med Chem | 1985 | 3892003 | Yes |
1352 | 1872 | 1872.0 | 0.0 | 0.0 | Cognitive maps in rats and men. | E C Tolman | Psychol Rev | 1948 | 18870876 | Yes |
1353 | 13073 | 1867.6 | 465.4 | 66.5 | Assessing the quality of reports of randomized clinical trials: is blinding necessary? | A R Jadad, R A Moore, D Carroll, C Jenkinson, D J Reynolds, D J Gavaghan, H J McQuay | Control Clin Trials | 1996 | 8721797 | Yes |
1354 | 1867 | 1867.0 | 54.54 | 54.5 | Aging, cellular senescence, and cancer. | Judith Campisi | Annu Rev Physiol | 2013 | 23140366 | No |
1355 | 5600 | 1866.7 | 420.25 | 140.1 | An interactive web-based dashboard to track COVID-19 in real time. | Ensheng Dong, Hongru Du, Lauren Gardner | Lancet Infect Dis | 2020 | 32087114 | Yes |
1356 | 3733 | 1866.5 | 82.92 | 41.5 | Amino acid substitution matrices from protein blocks. | S Henikoff, J G Henikoff | Proc Natl Acad Sci U S A | 1992 | 1438297 | Yes |
1357 | 1866 | 1866.0 | 37.4 | 37.4 | Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. | R J Kaufman | Genes Dev | 1999 | 10346810 | No |
1358 | 1866 | 1866.0 | 43.93 | 43.9 | The mitochondrial permeability transition pore and its role in cell death. | M Crompton | Biochem J | 1999 | 10393078 | No |
1359 | 3732 | 1866.0 | 85.63 | 42.8 | PRODRG: a tool for high-throughput crystallography of protein-ligand complexes. | Alexander W Schüttelkopf, Daan M F van Aalten | Acta Crystallogr D Biol Crystallogr | 2004 | 15272157 | Yes |
1360 | 5596 | 1865.3 | 125.3 | 41.8 | A new statistical method for haplotype reconstruction from population data. | M Stephens, N J Smith, P Donnelly | Am J Hum Genet | 2001 | 11254454 | Yes |
1361 | 1865 | 1865.0 | 50.58 | 50.6 | Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus. | Ralph A Defronzo | Diabetes | 2009 | 19336687 | No |
1362 | 1859 | 1859.0 | 48.68 | 48.7 | Hepatitis B virus infection. | W M Lee | N Engl J Med | 1997 | 9392700 | No |
1363 | 1859 | 1859.0 | 41.21 | 41.2 | Fabrication of novel biomaterials through molecular self-assembly. | Shuguang Zhang | Nat Biotechnol | 2003 | 14520402 | No |
1364 | 3718 | 1859.0 | 78.59 | 39.3 | Raster3D: photorealistic molecular graphics. | E A Merritt, D J Bacon | Methods Enzymol | 1997 | 18488322 | Yes |
1365 | 1858 | 1858.0 | 56.13 | 56.1 | The atom economy--a search for synthetic efficiency. | B M Trost | Science | 1991 | 1962206 | Yes |
1366 | 1858 | 1858.0 | 52.08 | 52.1 | Molecular weight determination of protein-dodecyl sulfate complexes by gel electrophoresis in a discontinuous buffer system. | D M Neville | J Biol Chem | 1971 | 5127429 | Yes |
1367 | 1857 | 1857.0 | 41.69 | 41.7 | Global cancer statistics in the year 2000. | D M Parkin | Lancet Oncol | 2001 | 11905707 | No |
1368 | 1856 | 1856.0 | 45.47 | 45.5 | Evolutionary relationship of DNA sequences in finite populations. | F Tajima | Genetics | 1983 | 6628982 | Yes |
1369 | 1855 | 1855.0 | 77.28 | 77.3 | Optical properties of biological tissues: a review. | Steven L Jacques | Phys Med Biol | 2013 | 23666068 | No |
1370 | 7418 | 1854.5 | 205.87 | 51.5 | Comorbidity measures for use with administrative data. | A Elixhauser, C Steiner, D R Harris, R M Coffey | Med Care | 1998 | 9431328 | Yes |
1371 | 3708 | 1854.0 | 105.54 | 52.8 | Molecular mechanisms and clinical applications of angiogenesis. | Peter Carmeliet, Rakesh K Jain | Nature | 2011 | 21593862 | No |
1372 | 1853 | 1853.0 | 53.2 | 53.2 | Perceptual symbol systems. | L W Barsalou | Behav Brain Sci | 1999 | 11301525 | No |
1373 | 1852 | 1852.0 | 37.27 | 37.3 | Evolutionary rate at the molecular level. | M Kimura | Nature | 1968 | 5637732 | Yes |
1374 | 5556 | 1852.0 | 138.93 | 46.3 | Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. | Z N Oltvai, C L Milliman, S J Korsmeyer | Cell | 1993 | 8358790 | Yes |
1375 | 7407 | 1851.8 | 179.0 | 44.8 | Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. | A Shevchenko, M Wilm, O Vorm, M Mann | Anal Chem | 1996 | 8779443 | Yes |
1376 | 3703 | 1851.5 | 100.13 | 50.1 | Biofilms: survival mechanisms of clinically relevant microorganisms. | Rodney M Donlan, J William Costerton | Clin Microbiol Rev | 2002 | 11932229 | No |
1377 | 1851 | 1851.0 | 85.11 | 85.1 | Determinants of low birth weight: methodological assessment and meta-analysis. | M S Kramer | Bull World Health Organ | 1987 | 3322602 | No |
1378 | 3702 | 1851.0 | 76.68 | 38.3 | Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. | C D Nobes, A Hall | Cell | 1995 | 7536630 | Yes |
1379 | 14783 | 1847.9 | 415.03 | 51.9 | Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. | R K Saiki, D H Gelfand, S Stoffel, S J Scharf, R Higuchi, G T Horn, K B Mullis, H A Erlich | Science | 1988 | 2448875 | Yes |
1380 | 5540 | 1846.7 | 122.16 | 40.7 | Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. | Michael W Pfaffl, Graham W Horgan, Leo Dempfle | Nucleic Acids Res | 2002 | 11972351 | Yes |
1381 | 1846 | 1846.0 | 48.43 | 48.4 | The comet assay for DNA damage and repair: principles, applications, and limitations. | Andrew R Collins | Mol Biotechnol | 2004 | 15004294 | No |
1382 | 3691 | 1845.5 | 128.45 | 64.2 | miRBase: annotating high confidence microRNAs using deep sequencing data. | Ana Kozomara, Sam Griffiths-Jones | Nucleic Acids Res | 2014 | 24275495 | Yes |
1383 | 3690 | 1845.0 | 112.59 | 56.3 | Genome editing. The new frontier of genome engineering with CRISPR-Cas9. | Jennifer A Doudna, Emmanuelle Charpentier | Science | 2014 | 25430774 | No |
1384 | 1845 | 1845.0 | 138.64 | 138.6 | User's guide to correlation coefficients. | Haldun Akoglu | Turk J Emerg Med | 2018 | 30191186 | No |
1385 | 3689 | 1844.5 | 53.02 | 26.5 | Immunoassay of insulin with insulin-antibody precipitate. | C N Hales, P J Randle | Biochem J | 1963 | 13952078 | Yes |
1386 | 3688 | 1844.0 | 126.25 | 63.1 | The Oswestry Disability Index. | J C Fairbank, P B Pynsent | Spine (Phila Pa 1976) | 2000 | 11074683 | No |
1387 | 1841 | 1841.0 | 56.96 | 57.0 | The inverse care law. | J T Hart | Lancet | 1971 | 4100731 | Yes |
1388 | 1841 | 1841.0 | 45.01 | 45.0 | Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials. | Fiona Turnbull | Lancet | 2003 | 14615107 | Yes |
1389 | 3679 | 1839.5 | 120.4 | 60.2 | Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. | R A DeFronzo, E Ferrannini | Diabetes Care | 1991 | 2044434 | No |
1390 | 11032 | 1838.7 | 321.91 | 53.7 | Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. | Ronald C Kessler, Patricia Berglund, Olga Demler, Robert Jin, Kathleen R Merikangas, Ellen E Walters | Arch Gen Psychiatry | 2005 | 15939837 | Yes |
1391 | 3677 | 1838.5 | 244.49 | 122.2 | Interactive Tree Of Life (iTOL) v4: recent updates and new developments. | Ivica Letunic, Peer Bork | Nucleic Acids Res | 2019 | 30931475 | Yes |
1392 | 3676 | 1838.0 | 76.27 | 38.1 | Cell death: critical control points. | Nika N Danial, Stanley J Korsmeyer | Cell | 2004 | 14744432 | No |
1393 | 3674 | 1837.0 | 110.66 | 55.3 | New method for quantitative determination of uronic acids. | N Blumenkrantz, G Asboe-Hansen | Anal Biochem | 1973 | 4269305 | Yes |
1394 | 1837 | 1837.0 | 41.35 | 41.4 | DNA topoisomerases. | J C Wang | Annu Rev Biochem | 1996 | 8811192 | No |
1395 | 1837 | 1837.0 | 36.69 | 36.7 | Molecular regulation of vessel maturation. | Rakesh K Jain | Nat Med | 2003 | 12778167 | No |
1396 | 7344 | 1836.0 | 339.76 | 84.9 | Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. | D J Sahn, A DeMaria, J Kisslo, A Weyman | Circulation | 1978 | 709763 | Yes |
1397 | 1836 | 1836.0 | 44.04 | 44.0 | A classification of hand preference by association analysis. | M Annett | Br J Psychol | 1970 | 5457503 | Yes |
1398 | 1836 | 1836.0 | 17.8 | 17.8 | A Method Of Measuring Eye Movement Using A Scleral Search Coil In A Magnetic Field. | D A Robinson | IEEE Trans Biomed Eng | 1963 | 14121113 | Yes |
1399 | 3671 | 1835.5 | 87.09 | 43.5 | Variations in the pattern of pubertal changes in boys. | W A Marshall, J M Tanner | Arch Dis Child | 1970 | 5440182 | Yes |
1400 | 1833 | 1833.0 | 67.9 | 67.9 | Physiological aspects of primary hypertension. | B Folkow | Physiol Rev | 1982 | 6461865 | No |
1401 | 1833 | 1833.0 | 45.82 | 45.8 | Flavonoid biosynthesis. A colorful model for genetics, biochemistry, cell biology, and biotechnology. | B Winkel-Shirley | Plant Physiol | 2001 | 11402179 | No |
1402 | 5496 | 1832.0 | 121.17 | 40.4 | A rapid method for the isolation of functional thymus-derived murine lymphocytes. | M H Julius, E Simpson, L A Herzenberg | Eur J Immunol | 1973 | 4587740 | Yes |
1403 | 1832 | 1832.0 | 36.22 | 36.2 | MicroRNA biogenesis: coordinated cropping and dicing. | V Narry Kim | Nat Rev Mol Cell Biol | 2005 | 15852042 | No |
1404 | 1830 | 1830.0 | 35.19 | 35.2 | Cancer and the chemokine network. | Fran Balkwill | Nat Rev Cancer | 2004 | 15229479 | No |
1405 | 1827 | 1827.0 | 65.99 | 66.0 | Why patients use alternative medicine: results of a national study. | J A Astin | JAMA | 1998 | 9605899 | Yes |
1406 | 3650 | 1825.0 | 87.43 | 43.7 | Macrophage diversity enhances tumor progression and metastasis. | Bin-Zhi Qian, Jeffrey W Pollard | Cell | 2010 | 20371344 | No |
1407 | 1824 | 1824.0 | 51.28 | 51.3 | Oxidative stress: oxidants and antioxidants. | H Sies | Exp Physiol | 1997 | 9129943 | No |
1408 | 3648 | 1824.0 | 93.92 | 47.0 | Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation. | M A Nitsche, W Paulus | J Physiol | 2000 | 10990547 | Yes |
1409 | 1822 | 1822.0 | 47.03 | 47.0 | Protein denaturation. | C Tanford | Adv Protein Chem | 1968 | 4882248 | No |
1410 | 1822 | 1822.0 | 69.74 | 69.7 | Reliability and validity studies of the WHO--Composite International Diagnostic Interview (CIDI): a critical review. | H U Wittchen | J Psychiatr Res | 1994 | 8064641 | No |
1411 | 1822 | 1822.0 | 48.9 | 48.9 | Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution. | H LeVine | Protein Sci | 1993 | 8453378 | Yes |
1412 | 1822 | 1822.0 | 39.99 | 40.0 | Recognition of microorganisms and activation of the immune response. | Ruslan Medzhitov | Nature | 2007 | 17943118 | No |
1413 | 1819 | 1819.0 | 48.49 | 48.5 | What we can do and what we cannot do with fMRI. | Nikos K Logothetis | Nature | 2008 | 18548064 | No |
1414 | 5449 | 1816.3 | 167.04 | 55.7 | Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. | P A Wolf, R D Abbott, W B Kannel | Stroke | 1991 | 1866765 | Yes |
1415 | 1816 | 1816.0 | 49.29 | 49.3 | Leptospirosis. | P N Levett | Clin Microbiol Rev | 2001 | 11292640 | No |
1416 | 5447 | 1815.7 | 102.54 | 34.2 | Surfing the p53 network. | B Vogelstein, D Lane, A J Levine | Nature | 2000 | 11099028 | No |
1417 | 3629 | 1814.5 | 92.48 | 46.2 | Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. | K D McCarthy, J de Vellis | J Cell Biol | 1980 | 6248568 | Yes |
1418 | 5443 | 1814.3 | 143.88 | 48.0 | Median-joining networks for inferring intraspecific phylogenies. | H J Bandelt, P Forster, A Röhl | Mol Biol Evol | 1999 | 10331250 | Yes |
1419 | 5443 | 1814.3 | 113.24 | 37.7 | A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays. | J H Zhang, T D Chung, K R Oldenburg | J Biomol Screen | 1999 | 10838414 | Yes |
1420 | 3628 | 1814.0 | 96.85 | 48.4 | Receptive fields and functional architecture of monkey striate cortex. | D H Hubel, T N Wiesel | J Physiol | 1968 | 4966457 | Yes |
1421 | 1813 | 1813.0 | 65.52 | 65.5 | The Resonating Valence Bond State in La2CuO4 and Superconductivity. | P W Anderson | Science | 1987 | 17818979 | Yes |
1422 | 1812 | 1812.0 | 0.0 | 0.0 | The influence of some cations on an adenosine triphosphatase from peripheral nerves. | J C Skou | Biochim Biophys Acta | 1957 | 13412736 | Yes |
1423 | 1811 | 1811.0 | 54.97 | 55.0 | Social relationships and health. | Sheldon Cohen | Am Psychol | 2004 | 15554821 | No |
1424 | 1810 | 1810.0 | 53.69 | 53.7 | An overview of brominated flame retardants in the environment. | Cynthia A de Wit | Chemosphere | 2002 | 11999784 | No |
1425 | 1809 | 1809.0 | 87.05 | 87.0 | Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal. | S Cohen | J Biol Chem | 1962 | 13880319 | Yes |
1426 | 3618 | 1809.0 | 71.8 | 35.9 | A guided tour into subcellular colocalization analysis in light microscopy. | S Bolte, F P Cordelières | J Microsc | 2006 | 17210054 | Yes |
1427 | 3618 | 1809.0 | 159.16 | 79.6 | The amyloid hypothesis of Alzheimer's disease at 25 years. | Dennis J Selkoe, John Hardy | EMBO Mol Med | 2016 | 27025652 | No |
1428 | 1808 | 1808.0 | 59.06 | 59.1 | Heavy metal intensification of DAB-based HRP reaction product. | J C Adams | J Histochem Cytochem | 1981 | 7252134 | Yes |
1429 | 1808 | 1808.0 | 43.41 | 43.4 | Growth of the plant cell wall. | Daniel J Cosgrove | Nat Rev Mol Cell Biol | 2005 | 16261190 | No |
1430 | 9040 | 1808.0 | 299.92 | 60.0 | The hallmarks of aging. | Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer | Cell | 2013 | 23746838 | No |
1431 | 3615 | 1807.5 | 127.7 | 63.9 | The transtheoretical model of health behavior change. | J O Prochaska, W F Velicer | Am J Health Promot | 1997 | 10170434 | No |
1432 | 7230 | 1807.5 | 274.01 | 68.5 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | Int J Surg | 2010 | 20171303 | No |
1433 | 3615 | 1807.5 | 116.62 | 58.3 | Saliency, switching, attention and control: a network model of insula function. | Vinod Menon, Lucina Q Uddin | Brain Struct Funct | 2010 | 20512370 | No |
1434 | 9036 | 1807.2 | 235.45 | 47.1 | Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. | Sarah Wild, Gojka Roglic, Anders Green, Richard Sicree, Hilary King | Diabetes Care | 2004 | 15111519 | Yes |
1435 | 1806 | 1806.0 | 18.81 | 18.8 | Chromatin structure: a repeating unit of histones and DNA. | R D Kornberg | Science | 1974 | 4825889 | Yes |
1436 | 1806 | 1806.0 | 42.57 | 42.6 | Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. | D Lavanchy | J Viral Hepat | 2004 | 14996343 | No |
1437 | 1806 | 1806.0 | 59.92 | 59.9 | Functional and effective connectivity: a review. | Karl J Friston | Brain Connect | 2011 | 22432952 | No |
1438 | 7224 | 1806.0 | 2527.84 | 632.0 | Cancer statistics, 2023. | Rebecca L Siegel, Kimberly D Miller, Nikita Sandeep Wagle, Ahmedin Jemal | CA Cancer J Clin | 2023 | 36633525 | Yes |
1439 | 3611 | 1805.5 | 86.89 | 43.4 | Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. | Christian Haass, Dennis J Selkoe | Nat Rev Mol Cell Biol | 2007 | 17245412 | No |
1440 | 1805 | 1805.0 | 56.53 | 56.5 | Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. | M Zasloff | Proc Natl Acad Sci U S A | 1987 | 3299384 | Yes |
1441 | 1804 | 1804.0 | 35.53 | 35.5 | The effect of infections on susceptibility to autoimmune and allergic diseases. | Jean-Francois Bach | N Engl J Med | 2002 | 12239261 | No |
1442 | 1804 | 1804.0 | 72.02 | 72.0 | Whatever next? Predictive brains, situated agents, and the future of cognitive science. | Andy Clark | Behav Brain Sci | 2013 | 23663408 | No |
1443 | 10819 | 1803.2 | 322.81 | 53.8 | New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. | Stéphane Guindon, Jean-François Dufayard, Vincent Lefort, Maria Anisimova, Wim Hordijk, Olivier Gascuel | Syst Biol | 2010 | 20525638 | Yes |
1444 | 3606 | 1803.0 | 83.65 | 41.8 | The incidence of congenital heart disease. | Julien I E Hoffman, Samuel Kaplan | J Am Coll Cardiol | 2002 | 12084585 | No |
1445 | 1803 | 1803.0 | 39.07 | 39.1 | The hippo signaling pathway in development and cancer. | Duojia Pan | Dev Cell | 2010 | 20951342 | No |
1446 | 1801 | 1801.0 | 48.1 | 48.1 | New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. | R Y Tsien | Biochemistry | 1980 | 6770893 | Yes |
1447 | 1801 | 1801.0 | 43.92 | 43.9 | Adipose tissue, adipokines, and inflammation. | Giamila Fantuzzi | J Allergy Clin Immunol | 2005 | 15867843 | No |
1448 | 3602 | 1801.0 | 99.72 | 49.9 | The precuneus: a review of its functional anatomy and behavioural correlates. | Andrea E Cavanna, Michael R Trimble | Brain | 2006 | 16399806 | No |
1449 | 1800 | 1800.0 | 36.35 | 36.4 | Points of control in inflammation. | Carl Nathan | Nature | 2002 | 12490957 | No |
1450 | 1800 | 1800.0 | 72.09 | 72.1 | Macrophage Polarization. | Peter J Murray | Annu Rev Physiol | 2017 | 27813830 | No |
1451 | 7198 | 1799.5 | 237.31 | 59.3 | Common method biases in behavioral research: a critical review of the literature and recommended remedies. | Philip M Podsakoff, Scott B MacKenzie, Jeong-Yeon Lee, Nathan P Podsakoff | J Appl Psychol | 2003 | 14516251 | No |
1452 | 1799 | 1799.0 | 42.54 | 42.5 | Type III protein secretion systems in bacterial pathogens of animals and plants. | C J Hueck | Microbiol Mol Biol Rev | 1998 | 9618447 | No |
1453 | 1797 | 1797.0 | 49.57 | 49.6 | Porous scaffold design for tissue engineering. | Scott J Hollister | Nat Mater | 2005 | 16003400 | No |
1454 | 3592 | 1796.0 | 143.25 | 71.6 | Dermatology Life Quality Index (DLQI)--a simple practical measure for routine clinical use. | A Y Finlay, G K Khan | Clin Exp Dermatol | 1994 | 8033378 | Yes |
1455 | 3592 | 1796.0 | 168.09 | 84.0 | Making sense of Cronbach's alpha. | Mohsen Tavakol, Reg Dennick | Int J Med Educ | 2011 | 28029643 | No |
1456 | 3588 | 1794.0 | 181.35 | 90.7 | Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. | M Mihara, M Uchiyama | Anal Biochem | 1978 | 655387 | Yes |
1457 | 1794 | 1794.0 | 0.0 | 0.0 | The measurement of volume changes in human limbs. | R J Whitney | J Physiol | 1953 | 13085295 | Yes |
1458 | 5380 | 1793.3 | 140.83 | 46.9 | The metabolic syndrome--a new worldwide definition. | K George M M Alberti, Paul Zimmet, Jonathan Shaw | Lancet | 2005 | 16182882 | Yes |
1459 | 1793 | 1793.0 | 36.56 | 36.6 | Structure and regulation of voltage-gated Ca2+ channels. | W A Catterall | Annu Rev Cell Dev Biol | 2000 | 11031246 | No |
1460 | 12548 | 1792.6 | 419.55 | 59.9 | GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. | Gordon H Guyatt, Andrew D Oxman, Gunn E Vist, Regina Kunz, Yngve Falck-Ytter, Pablo Alonso-Coello, Holger J Schünemann | BMJ | 2008 | 18436948 | Yes |
1461 | 1792 | 1792.0 | 97.63 | 97.6 | Estimability and estimation in case-referent studies. | O Miettinen | Am J Epidemiol | 1976 | 1251836 | Yes |
1462 | 7164 | 1791.0 | 138.98 | 34.7 | Stem cells, cancer, and cancer stem cells. | T Reya, S J Morrison, M F Clarke, I L Weissman | Nature | 2001 | 11689955 | No |
1463 | 1791 | 1791.0 | 36.42 | 36.4 | Protein homology detection by HMM-HMM comparison. | Johannes Söding | Bioinformatics | 2005 | 15531603 | Yes |
1464 | 3581 | 1790.5 | 129.13 | 64.6 | The integrative review: updated methodology. | Robin Whittemore, Kathleen Knafl | J Adv Nurs | 2005 | 16268861 | Yes |
1465 | 3579 | 1789.5 | 70.67 | 35.3 | An automated method for finding molecular complexes in large protein interaction networks. | Gary D Bader, Christopher W V Hogue | BMC Bioinformatics | 2003 | 12525261 | Yes |
1466 | 3579 | 1789.5 | 135.34 | 67.7 | The Emerging Hallmarks of Cancer Metabolism. | Natalya N Pavlova, Craig B Thompson | Cell Metab | 2016 | 26771115 | No |
1467 | 3578 | 1789.0 | 160.6 | 80.3 | Multiple receptors for dopamine. | J W Kebabian, D B Calne | Nature | 1979 | 215920 | No |
1468 | 1789 | 1789.0 | 62.42 | 62.4 | A cortical network for directed attention and unilateral neglect. | M M Mesulam | Ann Neurol | 1981 | 7032417 | No |
1469 | 1789 | 1789.0 | 73.86 | 73.9 | Adverse health effects of high-effort/low-reward conditions. | J Siegrist | J Occup Health Psychol | 1996 | 9547031 | No |
1470 | 3576 | 1788.0 | 85.85 | 42.9 | Protein folding in the cell. | M J Gething, J Sambrook | Nature | 1992 | 1731198 | No |
1471 | 1788 | 1788.0 | 61.1 | 61.1 | Falls in older people: epidemiology, risk factors and strategies for prevention. | Laurence Z Rubenstein | Age Ageing | 2006 | 16926202 | No |
1472 | 12512 | 1787.4 | 301.28 | 43.0 | Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. | William C Knowler, Elizabeth Barrett-Connor, Sarah E Fowler, Richard F Hamman, John M Lachin, Elizabeth A Walker, David M Nathan | N Engl J Med | 2002 | 11832527 | Yes |
1473 | 3572 | 1786.0 | 91.08 | 45.5 | Regulation of chromatin by histone modifications. | Andrew J Bannister, Tony Kouzarides | Cell Res | 2011 | 21321607 | No |
1474 | 7138 | 1784.5 | 300.73 | 75.2 | An inventory for measuring clinical anxiety: psychometric properties. | A T Beck, N Epstein, G Brown, R A Steer | J Consult Clin Psychol | 1988 | 3204199 | Yes |
1475 | 1783 | 1783.0 | 59.41 | 59.4 | Large-scale neurocognitive networks and distributed processing for attention, language, and memory. | M M Mesulam | Ann Neurol | 1990 | 2260847 | No |
1476 | 1783 | 1783.0 | 32.66 | 32.7 | Cellular roles of DNA topoisomerases: a molecular perspective. | James C Wang | Nat Rev Mol Cell Biol | 2002 | 12042765 | No |
1477 | 1782 | 1782.0 | 58.41 | 58.4 | The crisis in antibiotic resistance. | H C Neu | Science | 1992 | 1509257 | No |
1478 | 1782 | 1782.0 | 54.19 | 54.2 | Postsynaptic supersensitivity after 6-hydroxy-dopamine induced degeneration of the nigro-striatal dopamine system. | U Ungerstedt | Acta Physiol Scand Suppl | 1971 | 4332693 | Yes |
1479 | 3563 | 1781.5 | 80.15 | 40.1 | Shared principles in NF-kappaB signaling. | Matthew S Hayden, Sankar Ghosh | Cell | 2008 | 18267068 | No |
1480 | 1781 | 1781.0 | 36.31 | 36.3 | An extensively modified version of MolScript that includes greatly enhanced coloring capabilities. | R M Esnouf | J Mol Graph Model | 1997 | 9385560 | Yes |
1481 | 1780 | 1780.0 | 36.07 | 36.1 | Oxidative stress shortens telomeres. | Thomas von Zglinicki | Trends Biochem Sci | 2002 | 12114022 | Yes |
1482 | 1778 | 1778.0 | 36.75 | 36.8 | Excitatory actions of gaba during development: the nature of the nurture. | Yehezkel Ben-Ari | Nat Rev Neurosci | 2002 | 12209121 | No |
1483 | 3555 | 1777.5 | 89.43 | 44.7 | Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients. | S Schulman, C Kearon | J Thromb Haemost | 2005 | 15842354 | Yes |
1484 | 3554 | 1777.0 | 88.1 | 44.0 | Maturation of the head of bacteriophage T4. I. DNA packaging events. | U K Laemmli, M Favre | J Mol Biol | 1973 | 4204102 | Yes |
1485 | 3551 | 1775.5 | 73.81 | 36.9 | Why do cancers have high aerobic glycolysis? | Robert A Gatenby, Robert J Gillies | Nat Rev Cancer | 2004 | 15516961 | No |
1486 | 1775 | 1775.0 | 55.88 | 55.9 | The stress response in fish. | S E Wendelaar Bonga | Physiol Rev | 1997 | 9234959 | No |
1487 | 3547 | 1773.5 | 109.71 | 54.9 | Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. | F Denizot, R Lang | J Immunol Methods | 1986 | 3486233 | Yes |
1488 | 3547 | 1773.5 | 96.67 | 48.3 | Protective and pathogenic functions of macrophage subsets. | Peter J Murray, Thomas A Wynn | Nat Rev Immunol | 2011 | 21997792 | No |
1489 | 1771 | 1771.0 | 42.45 | 42.5 | Clinical application of C-reactive protein for cardiovascular disease detection and prevention. | Paul M Ridker | Circulation | 2003 | 12551853 | No |
1490 | 1771 | 1771.0 | 46.53 | 46.5 | Oxidative stress and neurodegeneration: where are we now? | Barry Halliwell | J Neurochem | 2006 | 16805774 | No |
1491 | 1771 | 1771.0 | 0.0 | 0.0 | The reaction of acetylcholine and other carboxylic acid derivatives with hydroxylamine, and its analytical application. | S Hestrin | J Biol Chem | 1949 | 18133390 | Yes |
1492 | 14162 | 1770.2 | 408.45 | 51.1 | The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. | Ziad S Nasreddine, Natalie A Phillips, Valérie Bédirian, Simon Charbonneau, Victor Whitehead, Isabelle Collin, Jeffrey L Cummings, Howard Chertkow | J Am Geriatr Soc | 2005 | 15817019 | Yes |
1493 | 1770 | 1770.0 | 66.37 | 66.4 | Simple proton spectroscopic imaging. | W T Dixon | Radiology | 1984 | 6089263 | Yes |
1494 | 3540 | 1770.0 | 88.54 | 44.3 | The biology of vascular endothelial growth factor. | N Ferrara, T Davis-Smyth | Endocr Rev | 1997 | 9034784 | No |
1495 | 1770 | 1770.0 | 63.15 | 63.1 | Modeling Development and Disease with Organoids. | Hans Clevers | Cell | 2016 | 27315476 | No |
1496 | 3539 | 1769.5 | 104.55 | 52.3 | The pathogenesis of rheumatoid arthritis. | Iain B McInnes, Georg Schett | N Engl J Med | 2011 | 22150039 | No |
1497 | 1769 | 1769.0 | 44.08 | 44.1 | Cellular basis of working memory. | P S Goldman-Rakic | Neuron | 1995 | 7695894 | No |
1498 | 1768 | 1768.0 | 42.25 | 42.2 | The relationship between the spleen colony-forming cell and the haemopoietic stem cell. | R Schofield | Blood Cells | 1978 | 747780 | Yes |
1499 | 1768 | 1768.0 | 58.66 | 58.7 | Drugs of abuse: anatomy, pharmacology and function of reward pathways. | G F Koob | Trends Pharmacol Sci | 1992 | 1604710 | No |
1500 | 3536 | 1768.0 | 74.9 | 37.5 | Insulin signalling and the regulation of glucose and lipid metabolism. | A R Saltiel, C R Kahn | Nature | 2001 | 11742412 | Yes |
1501 | 1767 | 1767.0 | 66.55 | 66.5 | Selenium and human health. | Margaret P Rayman | Lancet | 2012 | 22381456 | No |
1502 | 1766 | 1766.0 | 57.43 | 57.4 | Pineal melatonin: cell biology of its synthesis and of its physiological interactions. | R J Reiter | Endocr Rev | 1991 | 1649044 | No |
1503 | 1766 | 1766.0 | 33.19 | 33.2 | Network motifs: theory and experimental approaches. | Uri Alon | Nat Rev Genet | 2007 | 17510665 | No |
1504 | 17646 | 1764.6 | 553.29 | 55.3 | Measurement of protein using bicinchoninic acid. | P K Smith, R I Krohn, G T Hermanson, A K Mallia, F H Gartner, M D Provenzano, E K Fujimoto, N M Goeke, B J Olson, D C Klenk | Anal Biochem | 1985 | 3843705 | Yes |
1505 | 3529 | 1764.5 | 0.0 | 0.0 | Convergent and discriminant validation by the multitrait-multimethod matrix. | D T Campbell, D W Fiske | Psychol Bull | 1959 | 13634291 | Yes |
1506 | 3529 | 1764.5 | 71.03 | 35.5 | A general framework for weighted gene co-expression network analysis. | Bin Zhang, Steve Horvath | Stat Appl Genet Mol Biol | 2005 | 16646834 | Yes |
1507 | 1764 | 1764.0 | 49.22 | 49.2 | Transposition and fusion of the lac genes to selected promoters in Escherichia coli using bacteriophage lambda and Mu. | M J Casadaban | J Mol Biol | 1976 | 781293 | Yes |
1508 | 1764 | 1764.0 | 53.17 | 53.2 | Genetic differentiation and estimation of gene flow from F-statistics under isolation by distance. | F Rousset | Genetics | 1997 | 9093870 | Yes |
1509 | 1763 | 1763.0 | 57.19 | 57.2 | Validation of a decisional conflict scale. | A M O'Connor | Med Decis Making | 1995 | 7898294 | Yes |
1510 | 1763 | 1763.0 | 0.0 | 0.0 | The recurrence of intracranial meningiomas after surgical treatment. | D Simpson | J Neurol Neurosurg Psychiatry | 1957 | 13406590 | Yes |
1511 | 1763 | 1763.0 | 80.73 | 80.7 | Neutrophil extracellular traps in immunity and disease. | Venizelos Papayannopoulos | Nat Rev Immunol | 2018 | 28990587 | No |
1512 | 1761 | 1761.0 | 39.02 | 39.0 | Oogenesis in Xenopus laevis (Daudin). I. Stages of oocyte development in laboratory maintained animals. | J N Dumont | J Morphol | 1972 | 4109871 | Yes |
1513 | 1761 | 1761.0 | 47.28 | 47.3 | G proteins and dual control of adenylate cyclase. | A G Gilman | Cell | 1984 | 6321035 | Yes |
1514 | 1761 | 1761.0 | 46.15 | 46.1 | Chlorpromazine equivalent doses for the newer atypical antipsychotics. | Scott W Woods | J Clin Psychiatry | 2003 | 12823080 | No |
1515 | 3521 | 1760.5 | 45.62 | 22.8 | A complementation analysis of the restriction and modification of DNA in Escherichia coli. | H W Boyer, D Roulland-Dussoix | J Mol Biol | 1969 | 4896022 | Yes |
1516 | 3521 | 1760.5 | 140.99 | 70.5 | Methods for the thematic synthesis of qualitative research in systematic reviews. | James Thomas, Angela Harden | BMC Med Res Methodol | 2008 | 18616818 | Yes |
1517 | 3520 | 1760.0 | 82.91 | 41.5 | Origins and Mechanisms of miRNAs and siRNAs. | Richard W Carthew, Erik J Sontheimer | Cell | 2009 | 19239886 | No |
1518 | 5280 | 1760.0 | 303.06 | 101.0 | SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules. | Antoine Daina, Olivier Michielin, Vincent Zoete | Sci Rep | 2017 | 28256516 | Yes |
1519 | 1759 | 1759.0 | 41.63 | 41.6 | Tricine-SDS-PAGE. | Hermann Schägger | Nat Protoc | 2006 | 17406207 | Yes |
1520 | 1758 | 1758.0 | 42.65 | 42.6 | Why genes in pieces? | W Gilbert | Nature | 1978 | 622185 | Yes |
1521 | 3516 | 1758.0 | 86.46 | 43.2 | Matrix metalloproteinases. | H Nagase, J F Woessner | J Biol Chem | 1999 | 10419448 | No |
1522 | 1757 | 1757.0 | 40.79 | 40.8 | Areas, volumes, packing and protein structure. | F M Richards | Annu Rev Biophys Bioeng | 1977 | 326146 | No |
1523 | 1757 | 1757.0 | 46.47 | 46.5 | Interleukin-6: an overview. | J Van Snick | Annu Rev Immunol | 1990 | 2188664 | No |
1524 | 1756 | 1756.0 | 40.17 | 40.2 | Steroid receptor regulated transcription of specific genes and gene networks. | K R Yamamoto | Annu Rev Genet | 1985 | 3909942 | No |
1525 | 3508 | 1754.0 | 180.8 | 90.4 | Interrater reliability of a modified Ashworth scale of muscle spasticity. | R W Bohannon, M B Smith | Phys Ther | 1987 | 3809245 | Yes |
1526 | 1754 | 1754.0 | 42.45 | 42.5 | Maximum likelihood phylogenetic estimation from DNA sequences with variable rates over sites: approximate methods. | Z Yang | J Mol Evol | 1994 | 7932792 | Yes |
1527 | 5260 | 1753.3 | 118.25 | 39.4 | Inflammation and atherosclerosis. | Peter Libby, Paul M Ridker, Attilio Maseri | Circulation | 2002 | 11877368 | No |
1528 | 3503 | 1751.5 | 92.94 | 46.5 | Prediction of protein antigenic determinants from amino acid sequences. | T P Hopp, K R Woods | Proc Natl Acad Sci U S A | 1981 | 6167991 | Yes |
1529 | 1751 | 1751.0 | 61.03 | 61.0 | The role of hormone receptors and GTP-regulatory proteins in membrane transduction. | M Rodbell | Nature | 1980 | 6101906 | Yes |
1530 | 1750 | 1750.0 | 33.64 | 33.6 | Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. | Judith Campisi | Cell | 2005 | 15734683 | No |
1531 | 3499 | 1749.5 | 92.55 | 46.3 | The mirror-neuron system. | Giacomo Rizzolatti, Laila Craighero | Annu Rev Neurosci | 2004 | 15217330 | No |
1532 | 1749 | 1749.0 | 69.55 | 69.5 | Sample size in qualitative research. | M Sandelowski | Res Nurs Health | 1995 | 7899572 | Yes |
1533 | 5246 | 1748.7 | 135.51 | 45.2 | The rapid generation of mutation data matrices from protein sequences. | D T Jones, W R Taylor, J M Thornton | Comput Appl Biosci | 1992 | 1633570 | Yes |
1534 | 1748 | 1748.0 | 39.16 | 39.2 | ATPase activity of myosin correlated with speed of muscle shortening. | M Bárány | J Gen Physiol | 1967 | 4227924 | Yes |
1535 | 1748 | 1748.0 | 38.59 | 38.6 | The synaptic vesicle cycle: a cascade of protein-protein interactions. | T C Südhof | Nature | 1995 | 7791897 | No |
1536 | 3495 | 1747.5 | 150.89 | 75.4 | A standardized set of 260 pictures: norms for name agreement, image agreement, familiarity, and visual complexity. | J G Snodgrass, M Vanderwart | J Exp Psychol Hum Learn | 1980 | 7373248 | Yes |
1537 | 1747 | 1747.0 | 44.45 | 44.5 | The pathophysiology of tumor necrosis factors. | P Vassalli | Annu Rev Immunol | 1992 | 1590993 | No |
1538 | 3493 | 1746.5 | 98.58 | 49.3 | Alzheimer's disease. | Henry W Querfurth, Frank M LaFerla | N Engl J Med | 2010 | 20107219 | No |
1539 | 1746 | 1746.0 | 0.0 | 0.0 | A personality scale of manifest anxiety. | J A Taylor | J Abnorm Psychol | 1953 | 13052352 | Yes |
1540 | 1745 | 1745.0 | 56.83 | 56.8 | The polyvagal perspective. | Stephen W Porges | Biol Psychol | 2007 | 17049418 | No |
1541 | 3489 | 1744.5 | 114.09 | 57.0 | Neutrophil recruitment and function in health and inflammation. | Elzbieta Kolaczkowska, Paul Kubes | Nat Rev Immunol | 2013 | 23435331 | No |
1542 | 1744 | 1744.0 | 40.77 | 40.8 | Solvent-accessible surfaces of proteins and nucleic acids. | M L Connolly | Science | 1983 | 6879170 | Yes |
1543 | 8716 | 1743.2 | 198.31 | 39.7 | Stages of embryonic development of the zebrafish. | C B Kimmel, W W Ballard, S R Kimmel, B Ullmann, T F Schilling | Dev Dyn | 1995 | 8589427 | Yes |
1544 | 1743 | 1743.0 | 46.9 | 46.9 | Oxidative stress hypothesis in Alzheimer's disease. | W R Markesbery | Free Radic Biol Med | 1997 | 9165306 | No |
1545 | 5229 | 1743.0 | 156.55 | 52.2 | Simultaneous inference in general parametric models. | Torsten Hothorn, Frank Bretz, Peter Westfall | Biom J | 2008 | 18481363 | No |
1546 | 5229 | 1743.0 | 187.04 | 62.3 | Multiple imputation using chained equations: Issues and guidance for practice. | Ian R White, Patrick Royston, Angela M Wood | Stat Med | 2011 | 21225900 | Yes |
1547 | 3485 | 1742.5 | 135.86 | 67.9 | Assays of glutathione peroxidase. | L Flohé, W A Günzler | Methods Enzymol | 1984 | 6727659 | Yes |
1548 | 3483 | 1741.5 | 74.48 | 37.2 | Fibroblasts in cancer. | Raghu Kalluri, Michael Zeisberg | Nat Rev Cancer | 2006 | 16572188 | No |
1549 | 3481 | 1740.5 | 72.8 | 36.4 | Integrin signaling. | F G Giancotti, E Ruoslahti | Science | 1999 | 10446041 | No |
1550 | 3481 | 1740.5 | 71.15 | 35.6 | 'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease? | George Davey Smith, Shah Ebrahim | Int J Epidemiol | 2003 | 12689998 | No |
1551 | 8702 | 1740.4 | 214.26 | 42.9 | Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. | Alan S Go, Glenn M Chertow, Dongjie Fan, Charles E McCulloch, Chi-yuan Hsu | N Engl J Med | 2004 | 15385656 | Yes |
1552 | 6960 | 1740.0 | 136.07 | 34.0 | Transformation of intact yeast cells treated with alkali cations. | H Ito, Y Fukuda, K Murata, A Kimura | J Bacteriol | 1983 | 6336730 | Yes |
1553 | 1739 | 1739.0 | 73.98 | 74.0 | Dynamic properties of mammalian skeletal muscles. | R I Close | Physiol Rev | 1972 | 4256989 | No |
1554 | 1739 | 1739.0 | 50.12 | 50.1 | Risk and safety of repetitive transcranial magnetic stimulation: report and suggested guidelines from the International Workshop on the Safety of Repetitive Transcranial Magnetic Stimulation, June 5-7, 1996. | E M Wassermann | Electroencephalogr Clin Neurophysiol | 1998 | 9474057 | No |
1555 | 1737 | 1737.0 | 37.33 | 37.3 | Trastuzumab--mechanism of action and use in clinical practice. | Clifford A Hudis | N Engl J Med | 2007 | 17611206 | No |
1556 | 5209 | 1736.3 | 136.04 | 45.3 | A neural substrate of prediction and reward. | W Schultz, P Dayan, P R Montague | Science | 1997 | 9054347 | No |
1557 | 1736 | 1736.0 | 56.81 | 56.8 | Serum albumin. | T Peters | Adv Protein Chem | 1985 | 3904348 | No |
1558 | 1736 | 1736.0 | 38.83 | 38.8 | Tumor angiogenesis. | Robert S Kerbel | N Engl J Med | 2008 | 18463380 | No |
1559 | 1735 | 1735.0 | 39.48 | 39.5 | Mode of cell migration to the superficial layers of fetal monkey neocortex. | P Rakic | J Comp Neurol | 1972 | 4624784 | Yes |
1560 | 3468 | 1734.0 | 127.48 | 63.7 | A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms. | J A Horne, O Ostberg | Int J Chronobiol | 1976 | 1027738 | Yes |
1561 | 1734 | 1734.0 | 45.95 | 46.0 | THE WATER-WATER CYCLE IN CHLOROPLASTS: Scavenging of Active Oxygens and Dissipation of Excess Photons. | Kozi Asada | Annu Rev Plant Physiol Plant Mol Biol | 1999 | 15012221 | Yes |
1562 | 1734 | 1734.0 | 83.59 | 83.6 | International classification of sleep disorders-third edition: highlights and modifications. | Michael J Sateia | Chest | 2014 | 25367475 | No |
1563 | 6933 | 1733.2 | 198.66 | 49.7 | The validity of the Hospital Anxiety and Depression Scale. An updated literature review. | Ingvar Bjelland, Alv A Dahl, Tone Tangen Haug, Dag Neckelmann | J Psychosom Res | 2002 | 11832252 | No |
1564 | 1733 | 1733.0 | 62.58 | 62.6 | Cyclosporine. | B D Kahan | N Engl J Med | 1989 | 2687689 | No |
1565 | 1733 | 1733.0 | 54.14 | 54.1 | Glutamate: a neurotransmitter in mammalian brain. | F Fonnum | J Neurochem | 1984 | 6139418 | No |
1566 | 8660 | 1732.0 | 325.31 | 65.1 | UCHIME improves sensitivity and speed of chimera detection. | Robert C Edgar, Brian J Haas, Jose C Clemente, Christopher Quince, Rob Knight | Bioinformatics | 2011 | 21700674 | Yes |
1567 | 1731 | 1731.0 | 47.15 | 47.1 | The origins of the developmental origins theory. | D J P Barker | J Intern Med | 2007 | 17444880 | No |
1568 | 1730 | 1730.0 | 59.4 | 59.4 | Free radicals, antioxidants, and human disease: curiosity, cause, or consequence? | B Halliwell | Lancet | 1994 | 7915779 | No |
1569 | 1730 | 1730.0 | 45.91 | 45.9 | Synergy, antagonism, and what the chequerboard puts between them. | F C Odds | J Antimicrob Chemother | 2003 | 12805255 | No |
1570 | 3459 | 1729.5 | 90.64 | 45.3 | Cloned glutamate receptors. | M Hollmann, S Heinemann | Annu Rev Neurosci | 1994 | 8210177 | No |
1571 | 1729 | 1729.0 | 71.11 | 71.1 | Responses to depression and their effects on the duration of depressive episodes. | S Nolen-Hoeksema | J Abnorm Psychol | 1991 | 1757671 | No |
1572 | 5187 | 1729.0 | 112.17 | 37.4 | Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. | A Nicholls, K A Sharp, B Honig | Proteins | 1991 | 1758883 | Yes |
1573 | 1729 | 1729.0 | 40.74 | 40.7 | Two pathogenetic types of endometrial carcinoma. | J V Bokhman | Gynecol Oncol | 1983 | 6822361 | Yes |
1574 | 1729 | 1729.0 | 64.48 | 64.5 | Antibiotics in the aquatic environment--a review--part I. | Klaus Kümmerer | Chemosphere | 2009 | 19185900 | No |
1575 | 1728 | 1728.0 | 41.65 | 41.6 | Determination of free amino groups in proteins by trinitrobenzenesulfonic acid. | A F Habeeb | Anal Biochem | 1966 | 4161471 | Yes |
1576 | 3455 | 1727.5 | 93.98 | 47.0 | Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. | K B Mullis, F A Faloona | Methods Enzymol | 1987 | 3431465 | Yes |
1577 | 1727 | 1727.0 | 39.8 | 39.8 | Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining. | A Krishan | J Cell Biol | 1975 | 49354 | Yes |
1578 | 1727 | 1727.0 | 0.0 | 0.0 | Transformation Of Biochemically Deficient Strains Of Bacillus Subtilis By Deoxyribonucleate. | J Spizizen | Proc Natl Acad Sci U S A | 1958 | 16590310 | Yes |
1579 | 1726 | 1726.0 | 61.23 | 61.2 | Changes in the visual system of monocularly sutured or enucleated cats demonstrable with cytochrome oxidase histochemistry. | M Wong-Riley | Brain Res | 1979 | 223730 | Yes |
1580 | 3452 | 1726.0 | 103.29 | 51.6 | The benefits of being present: mindfulness and its role in psychological well-being. | Kirk Warren Brown, Richard M Ryan | J Pers Soc Psychol | 2003 | 12703651 | Yes |
1581 | 1726 | 1726.0 | 37.57 | 37.6 | AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. | D Grahame Hardie | Nat Rev Mol Cell Biol | 2007 | 17712357 | No |
1582 | 3450 | 1725.0 | 141.83 | 70.9 | Parkinson's disease. | Lorraine V Kalia, Anthony E Lang | Lancet | 2015 | 25904081 | No |
1583 | 3449 | 1724.5 | 131.18 | 65.6 | The three-factor eating questionnaire to measure dietary restraint, disinhibition and hunger. | A J Stunkard, S Messick | J Psychosom Res | 1985 | 3981480 | Yes |
1584 | 1724 | 1724.0 | 56.4 | 56.4 | Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli. | E M Witkin | Bacteriol Rev | 1976 | 795416 | No |
1585 | 3445 | 1722.5 | 96.55 | 48.3 | Astrocytes: biology and pathology. | Michael V Sofroniew, Harry V Vinters | Acta Neuropathol | 2010 | 20012068 | No |
1586 | 1721 | 1721.0 | 32.92 | 32.9 | Generating samples under a Wright-Fisher neutral model of genetic variation. | Richard R Hudson | Bioinformatics | 2002 | 11847089 | Yes |
1587 | 1721 | 1721.0 | 31.0 | 31.0 | CD4+ CD25+ suppressor T cells: more questions than answers. | Ethan M Shevach | Nat Rev Immunol | 2002 | 12093005 | No |
1588 | 3441 | 1720.5 | 86.58 | 43.3 | Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. | Steven E Nissen, Kathy Wolski | N Engl J Med | 2007 | 17517853 | Yes |
1589 | 5161 | 1720.3 | 230.95 | 77.0 | Some statistical methods useful in circulation research. | S Wallenstein, C L Zucker, J L Fleiss | Circ Res | 1980 | 7379260 | Yes |
1590 | 5159 | 1719.7 | 168.76 | 56.3 | A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. | J R Le Gall, S Lemeshow, F Saulnier | JAMA | 1993 | 8254858 | Yes |
1591 | 3438 | 1719.0 | 110.78 | 55.4 | Separate visual pathways for perception and action. | M A Goodale, A D Milner | Trends Neurosci | 1992 | 1374953 | No |
1592 | 1719 | 1719.0 | 56.51 | 56.5 | Microalbuminuria predicts clinical proteinuria and early mortality in maturity-onset diabetes. | C E Mogensen | N Engl J Med | 1984 | 6690964 | Yes |
1593 | 5156 | 1718.7 | 161.75 | 53.9 | Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. | H Esterbauer, R J Schaur, H Zollner | Free Radic Biol Med | 1991 | 1937131 | No |
1594 | 3437 | 1718.5 | 93.02 | 46.5 | Bronchopulmonary dysplasia. | A H Jobe, E Bancalari | Am J Respir Crit Care Med | 2001 | 11401896 | No |
1595 | 1717 | 1717.0 | 59.66 | 59.7 | Computerized transverse axial scanning (tomography). 1. Description of system. | G N Hounsfield | Br J Radiol | 1973 | 4757352 | Yes |
1596 | 1717 | 1717.0 | 52.59 | 52.6 | Stress and disorders of the stress system. | George P Chrousos | Nat Rev Endocrinol | 2009 | 19488073 | No |
1597 | 1716 | 1716.0 | 51.31 | 51.3 | Constructions of masculinity and their influence on men's well-being: a theory of gender and health. | W H Courtenay | Soc Sci Med | 2000 | 10741575 | No |
1598 | 5146 | 1715.3 | 113.11 | 37.7 | An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. | J K Eng, A L McCormack, J R Yates | J Am Soc Mass Spectrom | 1994 | 24226387 | Yes |
1599 | 1714 | 1714.0 | 44.56 | 44.6 | Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli. | G C Walker | Microbiol Rev | 1984 | 6371470 | No |
1600 | 1714 | 1714.0 | 33.53 | 33.5 | The synaptic vesicle cycle. | Thomas C Sudhof | Annu Rev Neurosci | 2004 | 15217342 | No |
1601 | 1713 | 1713.0 | 53.52 | 53.5 | Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances. | Joseph J Volpe | Lancet Neurol | 2009 | 19081519 | No |
1602 | 3425 | 1712.5 | 108.43 | 54.2 | Neurocircuitry of addiction. | George F Koob, Nora D Volkow | Neuropsychopharmacology | 2010 | 19710631 | No |
1603 | 1712 | 1712.0 | 41.92 | 41.9 | The smooth muscle cell. II. Growth of smooth muscle in culture and formation of elastic fibers. | R Ross | J Cell Biol | 1971 | 4327464 | Yes |
1604 | 1712 | 1712.0 | 0.0 | 0.0 | Note on the sampling error of the difference between correlated proportions or percentages. | Q McNEMAR | Psychometrika | 1947 | 20254758 | Yes |
1605 | 1712 | 1712.0 | 81.9 | 81.9 | Hydrogel: Preparation, characterization, and applications: A review. | Enas M Ahmed | J Adv Res | 2015 | 25750745 | No |
1606 | 3423 | 1711.5 | 78.58 | 39.3 | The BCL-2 protein family: opposing activities that mediate cell death. | Richard J Youle, Andreas Strasser | Nat Rev Mol Cell Biol | 2008 | 18097445 | No |
1607 | 1711 | 1711.0 | 68.78 | 68.8 | Negative symptoms in schizophrenia. Definition and reliability. | N C Andreasen | Arch Gen Psychiatry | 1982 | 7165477 | Yes |
1608 | 17108 | 1710.8 | 542.92 | 54.3 | The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. | F C Arnett, S M Edworthy, D A Bloch, D J McShane, J F Fries, N S Cooper, L A Healey, S R Kaplan, M H Liang, H S Luthra | Arthritis Rheum | 1988 | 3358796 | Yes |
1609 | 5132 | 1710.7 | 120.12 | 40.0 | Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. | Prateek Kumar, Steven Henikoff, Pauline C Ng | Nat Protoc | 2009 | 19561590 | Yes |
1610 | 3421 | 1710.5 | 71.3 | 35.6 | Fitting a mixture model by expectation maximization to discover motifs in biopolymers. | T L Bailey, C Elkan | Proc Int Conf Intell Syst Mol Biol | 1994 | 7584402 | Yes |
1611 | 3420 | 1710.0 | 223.06 | 111.5 | The structure of coping. | L I Pearlin, C Schooler | J Health Soc Behav | 1978 | 649936 | Yes |
1612 | 1710 | 1710.0 | 31.35 | 31.4 | How eukaryotic transcriptional activators work. | M Ptashne | Nature | 1988 | 3050531 | No |
1613 | 1710 | 1710.0 | 38.54 | 38.5 | Effects of cytochalasin and phalloidin on actin. | J A Cooper | J Cell Biol | 1987 | 3312229 | No |
1614 | 1709 | 1709.0 | 64.82 | 64.8 | Modeling and variable selection in epidemiologic analysis. | S Greenland | Am J Public Health | 1989 | 2916724 | Yes |
1615 | 3418 | 1709.0 | 86.35 | 43.2 | Quantum dot bioconjugates for ultrasensitive nonisotopic detection. | W C Chan, S Nie | Science | 1998 | 9748158 | Yes |
1616 | 1709 | 1709.0 | 0.0 | 0.0 | The general adaptation syndrome and the diseases of adaptation. | H Selye | J Clin Endocrinol Metab | 1946 | 21025115 | Yes |
1617 | 3416 | 1708.0 | 145.96 | 73.0 | A fluorometric method for determination of oxidized and reduced glutathione in tissues. | P J Hissin, R Hilf | Anal Biochem | 1976 | 962076 | Yes |
1618 | 3416 | 1708.0 | 82.44 | 41.2 | The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. | A E Bolton, W M Hunter | Biochem J | 1973 | 4733239 | Yes |
1619 | 1708 | 1708.0 | 39.32 | 39.3 | PLANT COLD ACCLIMATION: Freezing Tolerance Genes and Regulatory Mechanisms. | Michael F. Thomashow | Annu Rev Plant Physiol Plant Mol Biol | 1999 | 15012220 | Yes |
1620 | 1707 | 1707.0 | 43.18 | 43.2 | The importance of the ratio of omega-6/omega-3 essential fatty acids. | A P Simopoulos | Biomed Pharmacother | 2002 | 12442909 | No |
1621 | 1707 | 1707.0 | 34.51 | 34.5 | Neurotrophins and their receptors: a convergence point for many signalling pathways. | Moses V Chao | Nat Rev Neurosci | 2003 | 12671646 | No |
1622 | 1706 | 1706.0 | 36.81 | 36.8 | The NCI60 human tumour cell line anticancer drug screen. | Robert H Shoemaker | Nat Rev Cancer | 2006 | 16990858 | No |
1623 | 1706 | 1706.0 | 56.14 | 56.1 | Carboxylate-assisted transition-metal-catalyzed C-H bond functionalizations: mechanism and scope. | Lutz Ackermann | Chem Rev | 2011 | 21391562 | Yes |
1624 | 1705 | 1705.0 | 52.36 | 52.4 | A measure of population subdivision based on microsatellite allele frequencies. | M Slatkin | Genetics | 1995 | 7705646 | Yes |
1625 | 1705 | 1705.0 | 38.38 | 38.4 | Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): trends and problems. | S A Bustin | J Mol Endocrinol | 2002 | 12200227 | No |
1626 | 6816 | 1704.0 | 143.43 | 35.9 | Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. | E A Jaffe, R L Nachman, C G Becker, C R Minick | J Clin Invest | 1973 | 4355998 | Yes |
1627 | 6816 | 1704.0 | 196.84 | 49.2 | Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. | B Biswal, F Z Yetkin, V M Haughton, J S Hyde | Magn Reson Med | 1995 | 8524021 | Yes |
1628 | 1703 | 1703.0 | 58.76 | 58.8 | Cytokines in inflammatory bowel disease. | Markus F Neurath | Nat Rev Immunol | 2014 | 24751956 | No |
1629 | 10207 | 1701.2 | 284.88 | 47.5 | Positional cloning of the mouse obese gene and its human homologue. | Y Zhang, R Proenca, M Maffei, M Barone, L Leopold, J M Friedman | Nature | 1994 | 7984236 | Yes |
1630 | 3401 | 1700.5 | 49.65 | 24.8 | A "Direct-Coloring" Thiocholine Method For Cholinesterases. | M J Karnovsky, L Roots | J Histochem Cytochem | 1964 | 14187330 | Yes |
1631 | 1700 | 1700.0 | 46.76 | 46.8 | Multiple imputation of discrete and continuous data by fully conditional specification. | Stef van Buuren | Stat Methods Med Res | 2007 | 17621469 | Yes |
1632 | 3400 | 1700.0 | 87.53 | 43.8 | Multiple sclerosis. | Alastair Compston, Alasdair Coles | Lancet | 2008 | 18970977 | Yes |
1633 | 1699 | 1699.0 | 42.69 | 42.7 | The statistical analysis of enzyme kinetic data. | W W Cleland | Adv Enzymol Relat Areas Mol Biol | 1967 | 4881884 | No |
1634 | 1699 | 1699.0 | 36.04 | 36.0 | Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. | S L Friedman | J Biol Chem | 2000 | 10644669 | No |
1635 | 8495 | 1699.0 | 92.0 | 18.4 | Studies Of Illness In The Aged. The Index Of Adl: A Standardized Measure Of Biological And Psychosocial Function. | S Katz, A B Ford, R W Moskowitz, B A Jackson, M W Jaffe | JAMA | 1963 | 14044222 | Yes |
1636 | 3397 | 1698.5 | 92.67 | 46.3 | A perspective on cancer cell metastasis. | Christine L Chaffer, Robert A Weinberg | Science | 2011 | 21436443 | No |
1637 | 3396 | 1698.0 | 81.27 | 40.6 | CAP3: A DNA sequence assembly program. | X Huang, A Madan | Genome Res | 1999 | 10508846 | Yes |
1638 | 1698 | 1698.0 | 39.12 | 39.1 | A revolution in optical manipulation. | David G Grier | Nature | 2003 | 12917694 | No |
1639 | 1697 | 1697.0 | 55.32 | 55.3 | Synaptic density in human frontal cortex - developmental changes and effects of aging. | P R Huttenlocher | Brain Res | 1979 | 427544 | Yes |
1640 | 1697 | 1697.0 | 36.82 | 36.8 | Perceptions of epigenetics. | Adrian Bird | Nature | 2007 | 17522671 | Yes |
1641 | 1696 | 1696.0 | 31.17 | 31.2 | Cyclin-dependent kinases: engines, clocks, and microprocessors. | D O Morgan | Annu Rev Cell Dev Biol | 1997 | 9442875 | No |
1642 | 1696 | 1696.0 | 39.36 | 39.4 | Angiogenesis: an organizing principle for drug discovery? | Judah Folkman | Nat Rev Drug Discov | 2007 | 17396134 | No |
1643 | 18647 | 1695.2 | 582.44 | 52.9 | A new equation to estimate glomerular filtration rate. | Andrew S Levey, Lesley A Stevens, Christopher H Schmid, Yaping Lucy Zhang, Alejandro F Castro, Harold I Feldman, John W Kusek, Paul Eggers, Frederick Van Lente, Tom Greene, Josef Coresh | Ann Intern Med | 2009 | 19414839 | Yes |
1644 | 1695 | 1695.0 | 31.28 | 31.3 | Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy. | M G Gustafsson | J Microsc | 2000 | 10810003 | Yes |
1645 | 1695 | 1695.0 | 40.01 | 40.0 | The failing heart--an engine out of fuel. | Stefan Neubauer | N Engl J Med | 2007 | 17360992 | No |
1646 | 1695 | 1695.0 | 18.33 | 18.3 | Impulses and Physiological States in Theoretical Models of Nerve Membrane. | R Fitzhugh | Biophys J | 1961 | 19431309 | Yes |
1647 | 1694 | 1694.0 | 71.48 | 71.5 | The micronucleus test. | W Schmid | Mutat Res | 1975 | 48190 | Yes |
1648 | 6776 | 1694.0 | 266.85 | 66.7 | 16S ribosomal DNA amplification for phylogenetic study. | W G Weisburg, S M Barns, D A Pelletier, D J Lane | J Bacteriol | 1991 | 1987160 | Yes |
1649 | 1694 | 1694.0 | 51.65 | 51.6 | Pedigrees of some mutant strains of Escherichia coli K-12. | B J Bachmann | Bacteriol Rev | 1972 | 4568763 | No |
1650 | 6776 | 1694.0 | 206.68 | 51.7 | The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. | S P Baker, B O'Neill, W Haddon, W B Long | J Trauma | 1974 | 4814394 | Yes |
1651 | 1694 | 1694.0 | 44.19 | 44.2 | Carbonic anhydrase: chemistry, physiology, and inhibition. | T H Maren | Physiol Rev | 1967 | 4964060 | No |
1652 | 1694 | 1694.0 | 40.08 | 40.1 | A graphic method for the determination and presentation of binding parameters in a complex system. | H E Rosenthal | Anal Biochem | 1967 | 6048188 | Yes |
1653 | 5082 | 1694.0 | 109.47 | 36.5 | Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. | J E Darnell, I M Kerr, G R Stark | Science | 1994 | 8197455 | No |
1654 | 1693 | 1693.0 | 30.97 | 31.0 | Transplacental carcinogenesis by stilbestrol. | J Folkman | N Engl J Med | 1971 | 5556579 | Yes |
1655 | 3386 | 1693.0 | 93.5 | 46.8 | Biochemistry of multidrug resistance mediated by the multidrug transporter. | M M Gottesman, I Pastan | Annu Rev Biochem | 1993 | 8102521 | No |
1656 | 1693 | 1693.0 | 50.53 | 50.5 | Stress signalling pathways that impair prefrontal cortex structure and function. | Amy F T Arnsten | Nat Rev Neurosci | 2009 | 19455173 | No |
1657 | 3385 | 1692.5 | 219.74 | 109.9 | A clinical method of functional assessment of the shoulder. | C R Constant, A H Murley | Clin Orthop Relat Res | 1987 | 3791738 | Yes |
1658 | 3385 | 1692.5 | 71.82 | 35.9 | The epigenomics of cancer. | Peter A Jones, Stephen B Baylin | Cell | 2007 | 17320506 | No |
1659 | 1692 | 1692.0 | 20.22 | 20.2 | Amino acid difference formula to help explain protein evolution. | R Grantham | Science | 1974 | 4843792 | Yes |
1660 | 1692 | 1692.0 | 50.98 | 51.0 | Apoptosis in cancer: from pathogenesis to treatment. | Rebecca S Y Wong | J Exp Clin Cancer Res | 2011 | 21943236 | No |
1661 | 3383 | 1691.5 | 99.09 | 49.5 | An information-maximization approach to blind separation and blind deconvolution. | A J Bell, T J Sejnowski | Neural Comput | 1995 | 7584893 | Yes |
1662 | 1691 | 1691.0 | 39.75 | 39.8 | Five rules for the evolution of cooperation. | Martin A Nowak | Science | 2006 | 17158317 | No |
1663 | 1691 | 1691.0 | 51.23 | 51.2 | Chlorophyll fluorescence: a probe of photosynthesis in vivo. | Neil R Baker | Annu Rev Plant Biol | 2008 | 18444897 | No |
1664 | 1690 | 1690.0 | 45.25 | 45.2 | Integrins. | E Ruoslahti | J Clin Invest | 1991 | 1985087 | No |
1665 | 3380 | 1690.0 | 70.09 | 35.0 | A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids. | D Wessel, U I Flügge | Anal Biochem | 1984 | 6731838 | Yes |
1666 | 1688 | 1688.0 | 29.42 | 29.4 | Plastic Embedding Mixtures For Use In Electron Microscopy. | H H Mollenhauer | Stain Technol | 1964 | 14127791 | Yes |
1667 | 3375 | 1687.5 | 125.61 | 62.8 | The mini-mental state examination: a comprehensive review. | T N Tombaugh, N J McIntyre | J Am Geriatr Soc | 1992 | 1512391 | No |
1668 | 1687 | 1687.0 | 0.0 | 0.0 | The theory and applications of the exchange of inert gas at the lungs and tissues. | S S Kety | Pharmacol Rev | 1951 | 14833874 | Yes |
1669 | 1686 | 1686.0 | 40.22 | 40.2 | The molecular genetics of cancer. | J M Bishop | Science | 1987 | 3541204 | No |
1670 | 3372 | 1686.0 | 83.51 | 41.8 | Receptors for purines and pyrimidines. | V Ralevic, G Burnstock | Pharmacol Rev | 1998 | 9755289 | No |
1671 | 1686 | 1686.0 | 36.14 | 36.1 | Hematopoietic stem-cell transplantation. | Edward A Copelan | N Engl J Med | 2006 | 16641398 | No |
1672 | 3372 | 1686.0 | 82.81 | 41.4 | Protein structure prediction on the Web: a case study using the Phyre server. | Lawrence A Kelley, Michael J E Sternberg | Nat Protoc | 2009 | 19247286 | Yes |
1673 | 6739 | 1684.8 | 222.23 | 55.6 | SignalP 4.0: discriminating signal peptides from transmembrane regions. | Thomas Nordahl Petersen, Søren Brunak, Gunnar von Heijne, Henrik Nielsen | Nat Methods | 2011 | 21959131 | Yes |
1674 | 1684 | 1684.0 | 41.24 | 41.2 | Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia. | Shitij Kapur | Am J Psychiatry | 2003 | 12505794 | No |
1675 | 1683 | 1683.0 | 64.84 | 64.8 | Probiotics in man and animals. | R Fuller | J Appl Bacteriol | 1989 | 2666378 | No |
1676 | 3366 | 1683.0 | 78.52 | 39.3 | Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. | Robert Visse, Hideaki Nagase | Circ Res | 2003 | 12730128 | No |
1677 | 1682 | 1682.0 | 32.93 | 32.9 | Hox genes in vertebrate development. | R Krumlauf | Cell | 1994 | 7913880 | No |
1678 | 1682 | 1682.0 | 38.56 | 38.6 | NADPH oxidase: an update. | B M Babior | Blood | 1999 | 10029572 | No |
1679 | 5044 | 1681.3 | 199.1 | 66.4 | The MOS 36-Item Short-Form Health Survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. | C A McHorney, J E Ware, A E Raczek | Med Care | 1993 | 8450681 | Yes |
1680 | 1681 | 1681.0 | 42.98 | 43.0 | Understanding biofilm resistance to antibacterial agents. | David Davies | Nat Rev Drug Discov | 2003 | 12563302 | No |
1681 | 1681 | 1681.0 | 46.55 | 46.5 | Understanding organofluorine chemistry. An introduction to the C-F bond. | David O'Hagan | Chem Soc Rev | 2008 | 18197347 | No |
1682 | 10083 | 1680.5 | 205.53 | 34.3 | Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. | A Fire, S Xu, M K Montgomery, S A Kostas, S E Driver, C C Mello | Nature | 1998 | 9486653 | Yes |
1683 | 1680 | 1680.0 | 62.13 | 62.1 | Paced auditory serial-addition task: a measure of recovery from concussion. | D M Gronwall | Percept Mot Skills | 1977 | 866038 | Yes |
1684 | 1680 | 1680.0 | 58.43 | 58.4 | Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture. | A H Conney | Cancer Res | 1982 | 6814745 | No |
1685 | 1680 | 1680.0 | 37.3 | 37.3 | Introduction to NF-kappaB: players, pathways, perspectives. | T D Gilmore | Oncogene | 2006 | 17072321 | No |
1686 | 1680 | 1680.0 | 53.64 | 53.6 | The global impact of pre-eclampsia and eclampsia. | Lelia Duley | Semin Perinatol | 2009 | 19464502 | No |
1687 | 11757 | 1679.6 | 346.58 | 49.5 | AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility. | Garrett M Morris, Ruth Huey, William Lindstrom, Michel F Sanner, Richard K Belew, David S Goodsell, Arthur J Olson | J Comput Chem | 2009 | 19399780 | Yes |
1688 | 3358 | 1679.0 | 74.9 | 37.5 | ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking. | Matthew D Wilkerson, D Neil Hayes | Bioinformatics | 2010 | 20427518 | Yes |
1689 | 3357 | 1678.5 | 78.99 | 39.5 | The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. | P Angel, M Karin | Biochim Biophys Acta | 1991 | 1751545 | No |
1690 | 1678 | 1678.0 | 31.99 | 32.0 | Simple memory: a theory for archicortex. | D Marr | Philos Trans R Soc Lond B Biol Sci | 1971 | 4399412 | Yes |
1691 | 1677 | 1677.0 | 49.2 | 49.2 | Drugs which inhibit prostaglandin biosynthesis. | R J Flower | Pharmacol Rev | 1974 | 4208101 | Yes |
1692 | 1676 | 1676.0 | 30.71 | 30.7 | Neuroblastoma: biological insights into a clinical enigma. | Garrett M Brodeur | Nat Rev Cancer | 2003 | 12612655 | No |
1693 | 1676 | 1676.0 | 14.05 | 14.1 | Chromatographic Separation Of Human Brain Gangliosides. | L Svennerholm | J Neurochem | 1963 | 14066623 | Yes |
1694 | 1676 | 1676.0 | 46.94 | 46.9 | The many roles for fluorine in medicinal chemistry. | William K Hagmann | J Med Chem | 2008 | 18570365 | Yes |
1695 | 3351 | 1675.5 | 78.64 | 39.3 | Adipose tissue as an endocrine organ. | Erin E Kershaw, Jeffrey S Flier | J Clin Endocrinol Metab | 2004 | 15181022 | No |
1696 | 5023 | 1674.3 | 105.61 | 35.2 | Adjusting batch effects in microarray expression data using empirical Bayes methods. | W Evan Johnson, Cheng Li, Ariel Rabinovic | Biostatistics | 2007 | 16632515 | Yes |
1697 | 1674 | 1674.0 | 44.5 | 44.5 | Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture. | J A Miller | Cancer Res | 1970 | 4915745 | No |
1698 | 5021 | 1673.7 | 264.74 | 88.2 | Impact of Event Scale: a measure of subjective stress. | M Horowitz, N Wilner, W Alvarez | Psychosom Med | 1979 | 472086 | Yes |
1699 | 3346 | 1673.0 | 84.71 | 42.4 | ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins. | Markus Wiederstein, Manfred J Sippl | Nucleic Acids Res | 2007 | 17517781 | Yes |
1700 | 1672 | 1672.0 | 68.1 | 68.1 | A comparison of the two one-sided tests procedure and the power approach for assessing the equivalence of average bioavailability. | D J Schuirmann | J Pharmacokinet Biopharm | 1987 | 3450848 | Yes |
1701 | 1672 | 1672.0 | 58.45 | 58.5 | Amyloid deposits and amyloidosis. The beta-fibrilloses (first of two parts). | G G Glenner | N Engl J Med | 1980 | 6154243 | No |
1702 | 1672 | 1672.0 | 38.25 | 38.2 | The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. | D M Kingsley | Genes Dev | 1994 | 8299934 | No |
1703 | 1672 | 1672.0 | 46.94 | 46.9 | The in vitro micronucleus technique. | M Fenech | Mutat Res | 2000 | 11113469 | No |
1704 | 1672 | 1672.0 | 50.6 | 50.6 | Ordinary magic. Resilience processes in development. | A S Masten | Am Psychol | 2001 | 11315249 | Yes |
1705 | 1672 | 1672.0 | 0.0 | 0.0 | Axo-somatic and axo-dendritic synapses of the cerebral cortex: an electron microscope study. | E G Gray | J Anat | 1959 | 13829103 | Yes |
1706 | 1670 | 1670.0 | 82.3 | 82.3 | Measuring degree of physical dependence to tobacco smoking with reference to individualization of treatment. | K O Fagerström | Addict Behav | 1978 | 735910 | Yes |
1707 | 1670 | 1670.0 | 35.73 | 35.7 | An approximately unbiased test of phylogenetic tree selection. | Hidetoshi Shimodaira | Syst Biol | 2002 | 12079646 | Yes |
1708 | 1670 | 1670.0 | 37.72 | 37.7 | In vivo near-infrared fluorescence imaging. | John V Frangioni | Curr Opin Chem Biol | 2003 | 14580568 | No |
1709 | 1669 | 1669.0 | 53.69 | 53.7 | The role of senescent cells in ageing. | Jan M van Deursen | Nature | 2014 | 24848057 | No |
1710 | 3338 | 1669.0 | 155.04 | 77.5 | Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees. | Ivica Letunic, Peer Bork | Nucleic Acids Res | 2016 | 27095192 | Yes |
1711 | 3337 | 1668.5 | 109.81 | 54.9 | Role of free radicals and catalytic metal ions in human disease: an overview. | B Halliwell, J M Gutteridge | Methods Enzymol | 1990 | 2172697 | No |
1712 | 1668 | 1668.0 | 59.78 | 59.8 | Dual-task interference in simple tasks: data and theory. | H Pashler | Psychol Bull | 1994 | 7972591 | No |
1713 | 1668 | 1668.0 | 32.24 | 32.2 | Cell cycle checkpoints: preventing an identity crisis. | S J Elledge | Science | 1996 | 8939848 | No |
1714 | 1667 | 1667.0 | 74.68 | 74.7 | The structure and properties of the sense of coherence scale. | A Antonovsky | Soc Sci Med | 1993 | 8480217 | Yes |
1715 | 1667 | 1667.0 | 0.0 | 0.0 | Method for the determination of hexosamines in tissues. | N F Boas | J Biol Chem | 1953 | 13117829 | Yes |
1716 | 1667 | 1667.0 | 47.09 | 47.1 | Optimization of parameters for semiempirical methods V: modification of NDDO approximations and application to 70 elements. | James J P Stewart | J Mol Model | 2007 | 17828561 | Yes |
1717 | 1666 | 1666.0 | 52.7 | 52.7 | Metallothionein. | D H Hamer | Annu Rev Biochem | 1986 | 3527054 | No |
1718 | 1666 | 1666.0 | 46.52 | 46.5 | Semiempirical hybrid density functional with perturbative second-order correlation. | Stefan Grimme | J Chem Phys | 2006 | 16438568 | Yes |
1719 | 3332 | 1666.0 | 87.31 | 43.7 | Molecular mechanisms of long noncoding RNAs. | Kevin C Wang, Howard Y Chang | Mol Cell | 2011 | 21925379 | No |
1720 | 1665 | 1665.0 | 57.72 | 57.7 | The self-medication hypothesis of substance use disorders: a reconsideration and recent applications. | E J Khantzian | Harv Rev Psychiatry | 1997 | 9385000 | No |
1721 | 3326 | 1663.0 | 66.88 | 33.4 | Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. | Gary L Johnson, Razvan Lapadat | Science | 2002 | 12471242 | No |
1722 | 3325 | 1662.5 | 66.56 | 33.3 | Upstream and downstream of mTOR. | Nissim Hay, Nahum Sonenberg | Genes Dev | 2004 | 15314020 | No |
1723 | 1661 | 1661.0 | 23.46 | 23.5 | RNA-dependent DNA polymerase in virions of RNA tumour viruses. | D Baltimore | Nature | 1970 | 4316300 | Yes |
1724 | 1661 | 1661.0 | 54.71 | 54.7 | Number of people with glaucoma worldwide. | H A Quigley | Br J Ophthalmol | 1996 | 8695555 | No |
1725 | 1661 | 1661.0 | 39.54 | 39.5 | Inflammatory bowel disease: etiology and pathogenesis. | C Fiocchi | Gastroenterology | 1998 | 9649475 | No |
1726 | 4982 | 1660.7 | 117.87 | 39.3 | Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets. | Claus Lindbjerg Andersen, Jens Ledet Jensen, Torben Falck Ørntoft | Cancer Res | 2004 | 15289330 | Yes |
1727 | 1658 | 1658.0 | 46.87 | 46.9 | An improved procedure for serum creatine phosphokinase determination. | S B Rosalki | J Lab Clin Med | 1967 | 4381359 | Yes |
1728 | 3316 | 1658.0 | 54.3 | 27.1 | The Carbon Monoxide-Binding Pigment Of Liver Microsomes. Ii. Solubilization, Purification, And Properties. | T Omura, R Sato | J Biol Chem | 1964 | 14209972 | Yes |
1729 | 3316 | 1658.0 | 100.47 | 50.2 | How good are my data and what is the resolution? | Philip R Evans, Garib N Murshudov | Acta Crystallogr D Biol Crystallogr | 2013 | 23793146 | Yes |
1730 | 11605 | 1657.9 | 321.69 | 46.0 | BLAST+: architecture and applications. | Christiam Camacho, George Coulouris, Vahram Avagyan, Ning Ma, Jason Papadopoulos, Kevin Bealer, Thomas L Madden | BMC Bioinformatics | 2009 | 20003500 | Yes |
1731 | 3313 | 1656.5 | 64.04 | 32.0 | The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat. | J O'Keefe, J Dostrovsky | Brain Res | 1971 | 5124915 | Yes |
1732 | 3312 | 1656.0 | 81.33 | 40.7 | Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene. | M Grunstein, D S Hogness | Proc Natl Acad Sci U S A | 1975 | 1105573 | Yes |
1733 | 1656 | 1656.0 | 58.0 | 58.0 | The linear-quadratic formula and progress in fractionated radiotherapy. | J F Fowler | Br J Radiol | 1989 | 2670032 | No |
1734 | 1656 | 1656.0 | 40.89 | 40.9 | Marine viruses--major players in the global ecosystem. | Curtis A Suttle | Nat Rev Microbiol | 2007 | 17853907 | No |
1735 | 6621 | 1655.2 | 288.0 | 72.0 | A rating scale for mania: reliability, validity and sensitivity. | R C Young, J T Biggs, V E Ziegler, D A Meyer | Br J Psychiatry | 1978 | 728692 | Yes |
1736 | 1655 | 1655.0 | 41.85 | 41.9 | Neurotrophins and neuronal plasticity. | H Thoenen | Science | 1995 | 7570017 | No |
1737 | 1655 | 1655.0 | 47.17 | 47.2 | The basal ganglia: focused selection and inhibition of competing motor programs. | J W Mink | Prog Neurobiol | 1996 | 9004351 | No |
1738 | 1655 | 1655.0 | 34.87 | 34.9 | Neuronal calcium signaling. | M J Berridge | Neuron | 1998 | 9697848 | No |
1739 | 3309 | 1654.5 | 60.67 | 30.3 | Method for the isolation of intact islets of Langerhans from the rat pancreas. | P E Lacy, M Kostianovsky | Diabetes | 1967 | 5333500 | Yes |
1740 | 4963 | 1654.3 | 130.37 | 43.5 | Fast model-based estimation of ancestry in unrelated individuals. | David H Alexander, John Novembre, Kenneth Lange | Genome Res | 2009 | 19648217 | Yes |
1741 | 6615 | 1653.8 | 224.71 | 56.2 | Guidelines for the process of cross-cultural adaptation of self-report measures. | D E Beaton, C Bombardier, F Guillemin, M B Ferraz | Spine (Phila Pa 1976) | 2000 | 11124735 | No |
1742 | 6614 | 1653.5 | 152.48 | 38.1 | Use of T7 RNA polymerase to direct expression of cloned genes. | F W Studier, A H Rosenberg, J J Dunn, J W Dubendorff | Methods Enzymol | 1990 | 2199796 | Yes |
1743 | 1653 | 1653.0 | 30.86 | 30.9 | Switching and signaling at the telomere. | E H Blackburn | Cell | 2001 | 11572773 | No |
1744 | 3305 | 1652.5 | 68.6 | 34.3 | The Ki-67 protein: from the known and the unknown. | T Scholzen, J Gerdes | J Cell Physiol | 2000 | 10653597 | No |
1745 | 3304 | 1652.0 | 118.18 | 59.1 | Measuring emotion: the Self-Assessment Manikin and the Semantic Differential. | M M Bradley, P J Lang | J Behav Ther Exp Psychiatry | 1994 | 7962581 | Yes |
1746 | 1651 | 1651.0 | 43.0 | 43.0 | Task switching. | Stephen Monsell | Trends Cogn Sci | 2003 | 12639695 | Yes |
1747 | 3301 | 1650.5 | 75.11 | 37.6 | Human mesenchymal stem cells modulate allogeneic immune cell responses. | Sudeepta Aggarwal, Mark F Pittenger | Blood | 2005 | 15494428 | Yes |
1748 | 3300 | 1650.0 | 183.96 | 92.0 | Determination of the base composition of deoxyribonucleic acid from its thermal denaturation temperature. | J Marmur, P Doty | J Mol Biol | 1962 | 14470099 | Yes |
1749 | 9896 | 1649.3 | 228.33 | 38.1 | Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. | D J Slamon, G M Clark, S G Wong, W J Levin, A Ullrich, W L McGuire | Science | 1987 | 3798106 | Yes |
1750 | 3295 | 1647.5 | 71.29 | 35.6 | Protein structure comparison by alignment of distance matrices. | L Holm, C Sander | J Mol Biol | 1993 | 8377180 | Yes |
1751 | 1647 | 1647.0 | 73.22 | 73.2 | Mood and memory. | G H Bower | Am Psychol | 1981 | 7224324 | Yes |
1752 | 1646 | 1646.0 | 57.77 | 57.8 | The case-crossover design: a method for studying transient effects on the risk of acute events. | M Maclure | Am J Epidemiol | 1991 | 1985444 | Yes |
1753 | 1645 | 1645.0 | 37.52 | 37.5 | Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. | S C Manolagas | Endocr Rev | 2000 | 10782361 | No |
1754 | 1645 | 1645.0 | 32.96 | 33.0 | DNA in a material world. | Nadrian C Seeman | Nature | 2003 | 12540916 | No |
1755 | 1644 | 1644.0 | 42.52 | 42.5 | Alpha-crystallin can function as a molecular chaperone. | J Horwitz | Proc Natl Acad Sci U S A | 1992 | 1438232 | Yes |
1756 | 1644 | 1644.0 | 48.3 | 48.3 | Classification of inflammatory bowel disease. | J E Lennard-Jones | Scand J Gastroenterol Suppl | 1989 | 2617184 | Yes |
1757 | 3288 | 1644.0 | 101.5 | 50.8 | Neoantigens in cancer immunotherapy. | Ton N Schumacher, Robert D Schreiber | Science | 2015 | 25838375 | No |
1758 | 19723 | 1643.6 | 802.09 | 66.8 | Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology. | Sue Richards, Nazneen Aziz, Sherri Bale, David Bick, Soma Das, Julie Gastier-Foster, Wayne W Grody, Madhuri Hegde, Elaine Lyon, Elaine Spector, Karl Voelkerding, Heidi L Rehm | Genet Med | 2015 | 25741868 | No |
1759 | 1641 | 1641.0 | 45.02 | 45.0 | Turnover of inositol phospholipids and signal transduction. | Y Nishizuka | Science | 1984 | 6147898 | No |
1760 | 1641 | 1641.0 | 66.63 | 66.6 | Structure, Function, and Evolution of Coronavirus Spike Proteins. | Fang Li | Annu Rev Virol | 2016 | 27578435 | No |
1761 | 4920 | 1640.0 | 95.5 | 31.8 | T-Coffee: A novel method for fast and accurate multiple sequence alignment. | C Notredame, D G Higgins, J Heringa | J Mol Biol | 2000 | 10964570 | Yes |
1762 | 3279 | 1639.5 | 85.38 | 42.7 | Early identification of refractory epilepsy. | P Kwan, M J Brodie | N Engl J Med | 2000 | 10660394 | Yes |
1763 | 1639 | 1639.0 | 48.63 | 48.6 | Extracellular ATP: effects, sources and fate. | J L Gordon | Biochem J | 1986 | 3006665 | No |
1764 | 1639 | 1639.0 | 40.6 | 40.6 | External validity of randomised controlled trials: "to whom do the results of this trial apply?". | Peter M Rothwell | Lancet | 2005 | 15639683 | Yes |
1765 | 4914 | 1638.0 | 190.54 | 63.5 | Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression. | Jack Bowden, George Davey Smith, Stephen Burgess | Int J Epidemiol | 2015 | 26050253 | Yes |
1766 | 1638 | 1638.0 | 189.26 | 189.3 | COVID-19 and mental health: A review of the existing literature. | Ravi Philip Rajkumar | Asian J Psychiatr | 2020 | 32302935 | Yes |
1767 | 1636 | 1636.0 | 33.32 | 33.3 | Structural features in eukaryotic mRNAs that modulate the initiation of translation. | M Kozak | J Biol Chem | 1991 | 1939050 | No |
1768 | 1636 | 1636.0 | 29.07 | 29.1 | Maximum-likelihood density modification. | T C Terwilliger | Acta Crystallogr D Biol Crystallogr | 2000 | 10944333 | Yes |
1769 | 4907 | 1635.7 | 176.19 | 58.7 | Complex heatmaps reveal patterns and correlations in multidimensional genomic data. | Zuguang Gu, Roland Eils, Matthias Schlesner | Bioinformatics | 2016 | 27207943 | Yes |
1770 | 1635 | 1635.0 | 49.93 | 49.9 | Efficient analysis of experimental observations. | W J Dixon | Annu Rev Pharmacol Toxicol | 1980 | 7387124 | Yes |
1771 | 1635 | 1635.0 | 38.37 | 38.4 | The blood-brain barrier: bottleneck in brain drug development. | William M Pardridge | NeuroRx | 2005 | 15717053 | No |
1772 | 1634 | 1634.0 | 45.32 | 45.3 | Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction. | B Hille | J Gen Physiol | 1977 | 300786 | Yes |
1773 | 1633 | 1633.0 | 47.99 | 48.0 | A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. | Ozcan Erel | Clin Biochem | 2004 | 15003729 | Yes |
1774 | 1632 | 1632.0 | 58.49 | 58.5 | Aging, natural death, and the compression of morbidity. | J F Fries | N Engl J Med | 1980 | 7383070 | Yes |
1775 | 9789 | 1631.5 | 287.82 | 48.0 | The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. | Erik von Elm, Douglas G Altman, Matthias Egger, Stuart J Pocock, Peter C Gøtzsche, Jan P Vandenbroucke | Lancet | 2007 | 18064739 | Yes |
1776 | 1631 | 1631.0 | 53.66 | 53.7 | Archaea in coastal marine environments. | E F DeLong | Proc Natl Acad Sci U S A | 1992 | 1608980 | Yes |
1777 | 1631 | 1631.0 | 0.0 | 0.0 | Cerebral blood flow and oxygen consumption in man. | N A Lassen | Physiol Rev | 1959 | 13645234 | Yes |
1778 | 1631 | 1631.0 | 102.59 | 102.6 | A simple fluorimetric method for the estimation of free 11-hydroxycorticoids in human plasma. | D Mattingly | J Clin Pathol | 1962 | 14471419 | Yes |
1779 | 3261 | 1630.5 | 89.8 | 44.9 | Diarrheagenic Escherichia coli. | J P Nataro, J B Kaper | Clin Microbiol Rev | 1998 | 9457432 | No |
1780 | 1630 | 1630.0 | 36.35 | 36.4 | The Unified Medical Language System (UMLS): integrating biomedical terminology. | Olivier Bodenreider | Nucleic Acids Res | 2004 | 14681409 | Yes |
1781 | 1629 | 1629.0 | 56.46 | 56.5 | Frontal-subcortical circuits and human behavior. | J L Cummings | Arch Neurol | 1993 | 8352676 | No |
1782 | 1629 | 1629.0 | 56.81 | 56.8 | Multimodal approach to control postoperative pathophysiology and rehabilitation. | H Kehlet | Br J Anaesth | 1997 | 9175983 | No |
1783 | 1629 | 1629.0 | 40.05 | 40.0 | Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. | M J Meaney | Annu Rev Neurosci | 2001 | 11520931 | No |
1784 | 1629 | 1629.0 | 44.89 | 44.9 | Extended-spectrum beta-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat. | P A Bradford | Clin Microbiol Rev | 2001 | 11585791 | No |
1785 | 1628 | 1628.0 | 50.97 | 51.0 | Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage. | D W Choi | Trends Neurosci | 1988 | 2469166 | No |
1786 | 1628 | 1628.0 | 34.61 | 34.6 | Bone morphogenetic proteins: multifunctional regulators of vertebrate development. | B L Hogan | Genes Dev | 1996 | 8682290 | No |
1787 | 1627 | 1627.0 | 42.44 | 42.4 | Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp. | D A Dougherty | Science | 1996 | 8539615 | No |
1788 | 1627 | 1627.0 | 37.87 | 37.9 | Predictive values of body mass index and waist circumference for risk factors of certain related diseases in Chinese adults--study on optimal cut-off points of body mass index and waist circumference in Chinese adults. | Bei-Fan Zhou | Biomed Environ Sci | 2002 | 12046553 | Yes |
1789 | 1626 | 1626.0 | 70.9 | 70.9 | Neurogenetic adaptive mechanisms in alcoholism. | C R Cloninger | Science | 1987 | 2882604 | Yes |
1790 | 1626 | 1626.0 | 58.17 | 58.2 | Cell damage in the brain: a speculative synthesis. | B K Siesjö | J Cereb Blood Flow Metab | 1981 | 6276420 | No |
1791 | 1626 | 1626.0 | 43.15 | 43.1 | A more meaningful scoring system for determining the severity of coronary heart disease. | G G Gensini | Am J Cardiol | 1983 | 6823874 | Yes |
1792 | 1625 | 1625.0 | 75.21 | 75.2 | Computing Inter-Rater Reliability for Observational Data: An Overview and Tutorial. | Kevin A Hallgren | Tutor Quant Methods Psychol | 2012 | 22833776 | Yes |
1793 | 3250 | 1625.0 | 103.35 | 51.7 | The future of immune checkpoint therapy. | Padmanee Sharma, James P Allison | Science | 2015 | 25838373 | No |
1794 | 3250 | 1625.0 | 133.52 | 66.8 | Sex differences in immune responses. | Sabra L Klein, Katie L Flanagan | Nat Rev Immunol | 2016 | 27546235 | No |
1795 | 1624 | 1624.0 | 52.12 | 52.1 | Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue'). | M N Marsh | Gastroenterology | 1992 | 1727768 | No |
1796 | 1624 | 1624.0 | 81.44 | 81.4 | Muscle and tendon: properties, models, scaling, and application to biomechanics and motor control. | F E Zajac | Crit Rev Biomed Eng | 1989 | 2676342 | No |
1797 | 3248 | 1624.0 | 98.42 | 49.2 | Oxidative stress and diabetic complications. | Ferdinando Giacco, Michael Brownlee | Circ Res | 2010 | 21030723 | No |
1798 | 9743 | 1623.8 | 337.64 | 56.3 | Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. | L C Green, D A Wagner, J Glogowski, P L Skipper, J S Wishnok, S R Tannenbaum | Anal Biochem | 1982 | 7181105 | Yes |
1799 | 1622 | 1622.0 | 39.6 | 39.6 | Recognition of errors in three-dimensional structures of proteins. | M J Sippl | Proteins | 1993 | 8108378 | Yes |
1800 | 1622 | 1622.0 | 22.81 | 22.8 | Structural considerations in the interaction of DNA and acridines. | L S Lerman | J Mol Biol | 1961 | 13761054 | Yes |
1801 | 1622 | 1622.0 | 52.41 | 52.4 | Asthma phenotypes: the evolution from clinical to molecular approaches. | Sally E Wenzel | Nat Med | 2012 | 22561835 | No |
1802 | 3240 | 1620.0 | 96.55 | 48.3 | Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltons. | M Karas, F Hillenkamp | Anal Chem | 1988 | 3239801 | Yes |
1803 | 1620 | 1620.0 | 56.3 | 56.3 | Interhemispheric differences in the localization of psychological processes in man. | B Milner | Br Med Bull | 1971 | 4937273 | No |
1804 | 1620 | 1620.0 | 27.56 | 27.6 | Cell cycle checkpoint signaling through the ATM and ATR kinases. | R T Abraham | Genes Dev | 2001 | 11544175 | No |
1805 | 1620 | 1620.0 | 36.97 | 37.0 | Neurovascular regulation in the normal brain and in Alzheimer's disease. | Costantino Iadecola | Nat Rev Neurosci | 2004 | 15100718 | No |
1806 | 1620 | 1620.0 | 0.0 | 0.0 | Application of a Theory of Enzyme Specificity to Protein Synthesis. | D E Koshland | Proc Natl Acad Sci U S A | 1958 | 16590179 | Yes |
1807 | 3239 | 1619.5 | 76.79 | 38.4 | Rapid and sensitive protein similarity searches. | D J Lipman, W R Pearson | Science | 1985 | 2983426 | Yes |
1808 | 3239 | 1619.5 | 71.71 | 35.9 | Lipopolysaccharide endotoxins. | Christian R H Raetz, Chris Whitfield | Annu Rev Biochem | 2002 | 12045108 | No |
1809 | 1619 | 1619.0 | 30.24 | 30.2 | Germinal centers. | I C MacLennan | Annu Rev Immunol | 1994 | 8011279 | No |
1810 | 9708 | 1618.0 | 272.63 | 45.4 | A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. | Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier | Science | 2012 | 22745249 | Yes |
1811 | 4854 | 1618.0 | 240.11 | 80.0 | Radiomics: Images Are More than Pictures, They Are Data. | Robert J Gillies, Paul E Kinahan, Hedvig Hricak | Radiology | 2016 | 26579733 | Yes |
1812 | 1617 | 1617.0 | 46.03 | 46.0 | Fluorescence energy transfer as a spectroscopic ruler. | L Stryer | Annu Rev Biochem | 1978 | 354506 | No |
1813 | 1617 | 1617.0 | 31.07 | 31.1 | The microRNA Registry. | Sam Griffiths-Jones | Nucleic Acids Res | 2004 | 14681370 | Yes |
1814 | 1617 | 1617.0 | 63.58 | 63.6 | Nonalcoholic fatty liver disease: a systematic review. | Mary E Rinella | JAMA | 2015 | 26057287 | No |
1815 | 3233 | 1616.5 | 62.92 | 31.5 | The evolutionary fate and consequences of duplicate genes. | M Lynch, J S Conery | Science | 2000 | 11073452 | No |
1816 | 1616 | 1616.0 | 47.5 | 47.5 | Metalloproteinases and their inhibitors in matrix remodeling. | L M Matrisian | Trends Genet | 1990 | 2132731 | No |
1817 | 1616 | 1616.0 | 62.04 | 62.0 | AliView: a fast and lightweight alignment viewer and editor for large datasets. | Anders Larsson | Bioinformatics | 2014 | 25095880 | Yes |
1818 | 1615 | 1615.0 | 45.7 | 45.7 | Ionic dependence of glutamate neurotoxicity. | D W Choi | J Neurosci | 1987 | 2880938 | Yes |
1819 | 1615 | 1615.0 | 31.71 | 31.7 | Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing. | D I Svergun | Biophys J | 1999 | 10354416 | Yes |
1820 | 9688 | 1614.7 | 227.12 | 37.9 | GROMACS: fast, flexible, and free. | David Van Der Spoel, Erik Lindahl, Berk Hess, Gerrit Groenhof, Alan E Mark, Herman J C Berendsen | J Comput Chem | 2005 | 16211538 | Yes |
1821 | 1614 | 1614.0 | 30.34 | 30.3 | Protein kinases--the major drug targets of the twenty-first century? | Philip Cohen | Nat Rev Drug Discov | 2002 | 12120282 | No |
1822 | 1614 | 1614.0 | 44.92 | 44.9 | Gold-catalyzed organic reactions. | A Stephen K Hashmi | Chem Rev | 2007 | 17580975 | Yes |
1823 | 3227 | 1613.5 | 66.48 | 33.2 | Signaling to NF-kappaB. | Matthew S Hayden, Sankar Ghosh | Genes Dev | 2004 | 15371334 | No |
1824 | 3226 | 1613.0 | 124.81 | 62.4 | Alginate: properties and biomedical applications. | Kuen Yong Lee, David J Mooney | Prog Polym Sci | 2012 | 22125349 | Yes |
1825 | 1612 | 1612.0 | 16.28 | 16.3 | The genetical evolution of social behaviour. II. | W D Hamilton | J Theor Biol | 1964 | 5875340 | Yes |
1826 | 1612 | 1612.0 | 33.86 | 33.9 | The caveolae membrane system. | R G Anderson | Annu Rev Biochem | 1998 | 9759488 | No |
1827 | 3223 | 1611.5 | 100.58 | 50.3 | Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. | G R Gibson, M B Roberfroid | J Nutr | 1995 | 7782892 | No |
1828 | 3222 | 1611.0 | 76.77 | 38.4 | Cell signaling by receptor tyrosine kinases. | Mark A Lemmon, Joseph Schlessinger | Cell | 2010 | 20602996 | No |
1829 | 3220 | 1610.0 | 210.25 | 105.1 | ape 5.0: an environment for modern phylogenetics and evolutionary analyses in R. | Emmanuel Paradis, Klaus Schliep | Bioinformatics | 2019 | 30016406 | Yes |
1830 | 3219 | 1609.5 | 83.52 | 41.8 | Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. | D B Dill, D L Costill | J Appl Physiol | 1974 | 4850854 | Yes |
1831 | 3215 | 1607.5 | 62.31 | 31.2 | Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. | M E Greenberg, E B Ziff | Nature | 1984 | 6090941 | Yes |
1832 | 1607 | 1607.0 | 39.12 | 39.1 | The corticosteroid receptor hypothesis of depression. | F Holsboer | Neuropsychopharmacology | 2000 | 11027914 | No |
1833 | 3211 | 1605.5 | 120.01 | 60.0 | Universal chemical assay for the detection and determination of siderophores. | B Schwyn, J B Neilands | Anal Biochem | 1987 | 2952030 | Yes |
1834 | 1605 | 1605.0 | 36.91 | 36.9 | Insulin and insulin-like growth factor signalling in neoplasia. | Michael Pollak | Nat Rev Cancer | 2008 | 19029956 | No |
1835 | 1604 | 1604.0 | 49.1 | 49.1 | The role of the amygdala in fear and anxiety. | M Davis | Annu Rev Neurosci | 1992 | 1575447 | No |
1836 | 1604 | 1604.0 | 35.84 | 35.8 | Hypertrophic cardiomyopathy: a systematic review. | Barry J Maron | JAMA | 2002 | 11886323 | No |
1837 | 1604 | 1604.0 | 62.82 | 62.8 | α-band oscillations, attention, and controlled access to stored information. | Wolfgang Klimesch | Trends Cogn Sci | 2012 | 23141428 | No |
1838 | 3207 | 1603.5 | 62.71 | 31.4 | NF-kappaB regulation in the immune system. | Qiutang Li, Inder M Verma | Nat Rev Immunol | 2002 | 12360211 | No |
1839 | 1603 | 1603.0 | 40.7 | 40.7 | Aspergillus fumigatus and aspergillosis. | J P Latgé | Clin Microbiol Rev | 1999 | 10194462 | No |
1840 | 1603 | 1603.0 | 36.43 | 36.4 | Getting formal with dopamine and reward. | Wolfram Schultz | Neuron | 2002 | 12383780 | No |
1841 | 1603 | 1603.0 | 38.48 | 38.5 | Clinical features of metastatic bone disease and risk of skeletal morbidity. | Robert E Coleman | Clin Cancer Res | 2006 | 17062708 | No |
1842 | 3206 | 1603.0 | 168.06 | 84.0 | Natural Products as Sources of New Drugs from 1981 to 2014. | David J Newman, Gordon M Cragg | J Nat Prod | 2016 | 26852623 | No |
1843 | 3206 | 1603.0 | 153.51 | 76.8 | A simple practice guide for dose conversion between animals and human. | Anroop B Nair, Shery Jacob | J Basic Clin Pharm | 2016 | 27057123 | No |
1844 | 3205 | 1602.5 | 89.52 | 44.8 | Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research. | Sally S Dickerson, Margaret E Kemeny | Psychol Bull | 2004 | 15122924 | Yes |
1845 | 3205 | 1602.5 | 96.87 | 48.4 | LigPlot+: multiple ligand-protein interaction diagrams for drug discovery. | Roman A Laskowski, Mark B Swindells | J Chem Inf Model | 2011 | 21919503 | Yes |
1846 | 1602 | 1602.0 | 30.59 | 30.6 | Regulatory T cells, tumour immunity and immunotherapy. | Weiping Zou | Nat Rev Immunol | 2006 | 16557261 | No |
1847 | 3204 | 1602.0 | 117.38 | 58.7 | Elements of cancer immunity and the cancer-immune set point. | Daniel S Chen, Ira Mellman | Nature | 2017 | 28102259 | No |
1848 | 3203 | 1601.5 | 61.71 | 30.9 | Automated MAD and MIR structure solution. | T C Terwilliger, J Berendzen | Acta Crystallogr D Biol Crystallogr | 1999 | 10089316 | Yes |
1849 | 1601 | 1601.0 | 36.75 | 36.8 | VLA proteins in the integrin family: structures, functions, and their role on leukocytes. | M E Hemler | Annu Rev Immunol | 1990 | 2188667 | No |
1850 | 3201 | 1600.5 | 113.31 | 56.7 | Avoiding false positives with PCR. | S Kwok, R Higuchi | Nature | 1989 | 2716852 | Yes |
1851 | 3201 | 1600.5 | 92.96 | 46.5 | Software survey: VOSviewer, a computer program for bibliometric mapping. | Nees Jan van Eck, Ludo Waltman | Scientometrics | 2010 | 20585380 | Yes |
1852 | 1600 | 1600.0 | 34.38 | 34.4 | On finding all suboptimal foldings of an RNA molecule. | M Zuker | Science | 1989 | 2468181 | No |
1853 | 1600 | 1600.0 | 71.27 | 71.3 | The contribution of low birth weight to infant mortality and childhood morbidity. | M C McCormick | N Engl J Med | 1985 | 3880598 | No |
1854 | 1600 | 1600.0 | 42.34 | 42.3 | Precision mapping of quantitative trait loci. | Z B Zeng | Genetics | 1994 | 8013918 | Yes |
1855 | 1599 | 1599.0 | 36.26 | 36.3 | Cellular oncogenes and retroviruses. | J M Bishop | Annu Rev Biochem | 1983 | 6351725 | No |
1856 | 1599 | 1599.0 | 50.82 | 50.8 | Cellular defenses against damage from reactive oxygen species. | B P Yu | Physiol Rev | 1994 | 8295932 | No |
1857 | 1599 | 1599.0 | 48.04 | 48.0 | Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance. | L Bravo | Nutr Rev | 1998 | 9838798 | No |
1858 | 1599 | 1599.0 | 36.9 | 36.9 | A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. | D A Gewirtz | Biochem Pharmacol | 1999 | 10075079 | No |
1859 | 1599 | 1599.0 | 72.52 | 72.5 | Measurement of health state utilities for economic appraisal. | G W Torrance | J Health Econ | 1986 | 10311607 | No |
1860 | 1599 | 1599.0 | 34.35 | 34.4 | Mechanisms of bone metastasis. | G David Roodman | N Engl J Med | 2004 | 15084698 | No |
1861 | 3197 | 1598.5 | 94.82 | 47.4 | Unified approach for molecular dynamics and density-functional theory. | R Car, M Parrinello | Phys Rev Lett | 1985 | 10032153 | Yes |
1862 | 1598 | 1598.0 | 40.77 | 40.8 | Molecular biology of prion diseases. | S B Prusiner | Science | 1991 | 1675487 | No |
1863 | 1598 | 1598.0 | 31.48 | 31.5 | An analysis of vertebrate mRNA sequences: intimations of translational control. | M Kozak | J Cell Biol | 1991 | 1955461 | No |
1864 | 4794 | 1598.0 | 131.39 | 43.8 | Dating of the human-ape splitting by a molecular clock of mitochondrial DNA. | M Hasegawa, H Kishino, T Yano | J Mol Evol | 1985 | 3934395 | Yes |
1865 | 1598 | 1598.0 | 30.62 | 30.6 | The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept. | A G Pearse | J Histochem Cytochem | 1969 | 4143745 | No |
1866 | 3196 | 1598.0 | 69.25 | 34.6 | Neurotrophins: roles in neuronal development and function. | E J Huang, L F Reichardt | Annu Rev Neurosci | 2001 | 11520916 | No |
1867 | 1598 | 1598.0 | 31.04 | 31.0 | Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy. | R K Jain | Nat Med | 2001 | 11533692 | No |
1868 | 1598 | 1598.0 | 0.0 | 0.0 | Antigen-antibody reactions in gels. IV. Types of reactions in coordinated systems of diffusion. | O Ouchterlony | Acta Pathol Microbiol Scand | 1953 | 13079779 | Yes |
1869 | 3195 | 1597.5 | 65.26 | 32.6 | Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions. | E Krissinel, K Henrick | Acta Crystallogr D Biol Crystallogr | 2004 | 15572779 | Yes |
1870 | 3195 | 1597.5 | 92.67 | 46.3 | Density functionals with broad applicability in chemistry. | Yan Zhao, Donald G Truhlar | Acc Chem Res | 2008 | 18186612 | Yes |
1871 | 1597 | 1597.0 | 45.98 | 46.0 | The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system function. | R R Llinás | Science | 1988 | 3059497 | No |
1872 | 1597 | 1597.0 | 51.98 | 52.0 | Screening for prostate cancer: U.S. Preventive Services Task Force recommendation statement. | Virginia A Moyer | Ann Intern Med | 2012 | 22801674 | No |
1873 | 3193 | 1596.5 | 75.38 | 37.7 | Unravelling the pathogenesis of inflammatory bowel disease. | R J Xavier, D K Podolsky | Nature | 2007 | 17653185 | No |
1874 | 3193 | 1596.5 | 94.01 | 47.0 | Quality control and preprocessing of metagenomic datasets. | Robert Schmieder, Robert Edwards | Bioinformatics | 2011 | 21278185 | Yes |
1875 | 1596 | 1596.0 | 57.2 | 57.2 | Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons. | P Holzer | Pharmacol Rev | 1991 | 1852779 | No |
1876 | 1596 | 1596.0 | 28.85 | 28.9 | Altering the genome by homologous recombination. | M R Capecchi | Science | 1989 | 2660260 | No |
1877 | 3191 | 1595.5 | 67.4 | 33.7 | Inhibitors of mammalian G1 cyclin-dependent kinases. | C J Sherr, J M Roberts | Genes Dev | 1995 | 7758941 | No |
1878 | 3190 | 1595.0 | 87.81 | 43.9 | Polyamines. | C W Tabor, H Tabor | Annu Rev Biochem | 1984 | 6206782 | No |
1879 | 3190 | 1595.0 | 139.15 | 69.6 | MicroRNA therapeutics: towards a new era for the management of cancer and other diseases. | Rajesha Rupaimoole, Frank J Slack | Nat Rev Drug Discov | 2017 | 28209991 | No |
1880 | 1594 | 1594.0 | 39.33 | 39.3 | Tumor necrosis factor (TNF). | L J Old | Science | 1985 | 2413547 | Yes |
1881 | 3188 | 1594.0 | 77.61 | 38.8 | A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes. | S Tabor, C C Richardson | Proc Natl Acad Sci U S A | 1985 | 3156376 | Yes |
1882 | 3187 | 1593.5 | 204.27 | 102.1 | OrthoFinder: phylogenetic orthology inference for comparative genomics. | David M Emms, Steven Kelly | Genome Biol | 2019 | 31727128 | Yes |
1883 | 1593 | 1593.0 | 34.51 | 34.5 | Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. | G L Semenza | Annu Rev Cell Dev Biol | 1999 | 10611972 | No |
1884 | 1593 | 1593.0 | 33.91 | 33.9 | From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels. | W A Catterall | Neuron | 2000 | 10798388 | No |
1885 | 1593 | 1593.0 | 0.0 | 0.0 | Cerebral vascular accidents in patients over the age of 60. II. Prognosis. | J Rankin | Scott Med J | 1957 | 13432835 | Yes |
1886 | 14334 | 1592.7 | 440.69 | 49.0 | The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. | D V Sheehan, Y Lecrubier, K H Sheehan, P Amorim, J Janavs, E Weiller, T Hergueta, R Baker, G C Dunbar | J Clin Psychiatry | 1998 | 9881538 | No |
1887 | 4778 | 1592.7 | 116.03 | 38.7 | Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. | Earl S Ford, Wayne H Giles, William H Dietz | JAMA | 2002 | 11790215 | Yes |
1888 | 4777 | 1592.3 | 123.49 | 41.2 | Optimization by simulated annealing. | S Kirkpatrick, C D Gelatt, M P Vecchi | Science | 1983 | 17813860 | Yes |
1889 | 3182 | 1591.0 | 91.79 | 45.9 | Extended-connectivity fingerprints. | David Rogers, Mathew Hahn | J Chem Inf Model | 2010 | 20426451 | Yes |
1890 | 1591 | 1591.0 | 57.24 | 57.2 | A Protection Motivation Theory of Fear Appeals and Attitude Change1. | Ronald W Rogers | J Psychol | 1975 | 28136248 | Yes |
1891 | 3179 | 1589.5 | 89.55 | 44.8 | Accessories to the crime: functions of cells recruited to the tumor microenvironment. | Douglas Hanahan, Lisa M Coussens | Cancer Cell | 2012 | 22439926 | No |
1892 | 1589 | 1589.0 | 0.0 | 0.0 | Discharge patterns and functional organization of mammalian retina. | S W Kuffler | J Neurophysiol | 1953 | 13035466 | Yes |
1893 | 3178 | 1589.0 | 109.66 | 54.8 | The M1 and M2 paradigm of macrophage activation: time for reassessment. | Fernando O Martinez, Siamon Gordon | F1000Prime Rep | 2014 | 24669294 | No |
1894 | 3177 | 1588.5 | 187.22 | 93.6 | Rating systems in the evaluation of knee ligament injuries. | Y Tegner, J Lysholm | Clin Orthop Relat Res | 1985 | 4028566 | Yes |
1895 | 3177 | 1588.5 | 70.53 | 35.3 | The human plasma proteome: history, character, and diagnostic prospects. | N Leigh Anderson, Norman G Anderson | Mol Cell Proteomics | 2002 | 12488461 | No |
1896 | 1588 | 1588.0 | 110.77 | 110.8 | Anterior acromioplasty for the chronic impingement syndrome in the shoulder: a preliminary report. | C S Neer | J Bone Joint Surg Am | 1972 | 5054450 | Yes |
1897 | 1588 | 1588.0 | 49.3 | 49.3 | Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection. | W H Oldendorf | Am J Physiol | 1971 | 5124307 | Yes |
1898 | 3175 | 1587.5 | 91.14 | 45.6 | Oxidative stress, glutamate, and neurodegenerative disorders. | J T Coyle, P Puttfarcken | Science | 1993 | 7901908 | No |
1899 | 6350 | 1587.5 | 154.98 | 38.7 | Most mammalian mRNAs are conserved targets of microRNAs. | Robin C Friedman, Kyle Kai-How Farh, Christopher B Burge, David P Bartel | Genome Res | 2009 | 18955434 | Yes |
1900 | 4762 | 1587.3 | 115.38 | 38.5 | Two-photon laser scanning fluorescence microscopy. | W Denk, J H Strickler, W W Webb | Science | 1990 | 2321027 | Yes |
1901 | 1587 | 1587.0 | 35.65 | 35.6 | Thiazolidinediones. | Hannele Yki-Järvinen | N Engl J Med | 2004 | 15356308 | No |
1902 | 1587 | 1587.0 | 37.36 | 37.4 | The biology of incretin hormones. | Daniel J Drucker | Cell Metab | 2006 | 16517403 | No |
1903 | 1586 | 1586.0 | 29.79 | 29.8 | Immunosuppressive networks in the tumour environment and their therapeutic relevance. | Weiping Zou | Nat Rev Cancer | 2005 | 15776005 | No |
1904 | 1584 | 1584.0 | 50.29 | 50.3 | Which elements are excited in electrical stimulation of mammalian central nervous system: a review. | J B Ranck | Brain Res | 1975 | 1102064 | No |
1905 | 1584 | 1584.0 | 19.55 | 19.6 | Dithiothreitol, A New Protective Reagent For Sh Groups. | W W Cleland | Biochemistry | 1964 | 14192894 | Yes |
1906 | 1582 | 1582.0 | 48.95 | 49.0 | The law of attrition. | Gunther Eysenbach | J Med Internet Res | 2005 | 15829473 | Yes |
1907 | 1582 | 1582.0 | 36.02 | 36.0 | Neurotrophin-regulated signalling pathways. | Louis F Reichardt | Philos Trans R Soc Lond B Biol Sci | 2006 | 16939974 | No |
1908 | 3163 | 1581.5 | 98.29 | 49.1 | Palladium-catalyzed ligand-directed C-H functionalization reactions. | Thomas W Lyons, Melanie S Sanford | Chem Rev | 2010 | 20078038 | No |
1909 | 3162 | 1581.0 | 96.9 | 48.5 | Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. | D S Bredt, S H Snyder | Proc Natl Acad Sci U S A | 1990 | 1689048 | Yes |
1910 | 4743 | 1581.0 | 105.75 | 35.2 | Click Chemistry: Diverse Chemical Function from a Few Good Reactions. | Hartmuth C. Kolb, M G Finn, K. Barry Sharpless | Angew Chem Int Ed Engl | 2001 | 11433435 | Yes |
1911 | 3162 | 1581.0 | 67.4 | 33.7 | Complex networks orchestrate epithelial-mesenchymal transitions. | Jean Paul Thiery, Jonathan P Sleeman | Nat Rev Mol Cell Biol | 2006 | 16493418 | No |
1912 | 1581 | 1581.0 | 31.36 | 31.4 | The Buccaneer software for automated model building. 1. Tracing protein chains. | Kevin Cowtan | Acta Crystallogr D Biol Crystallogr | 2006 | 16929101 | Yes |
1913 | 1580 | 1580.0 | 42.78 | 42.8 | The complete general secretory pathway in gram-negative bacteria. | A P Pugsley | Microbiol Rev | 1993 | 8096622 | No |
1914 | 1580 | 1580.0 | 29.27 | 29.3 | How cells read TGF-beta signals. | J Massagué | Nat Rev Mol Cell Biol | 2000 | 11252892 | No |
1915 | 17380 | 1580.0 | 453.77 | 41.3 | The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. | Aaron McKenna, Matthew Hanna, Eric Banks, Andrey Sivachenko, Kristian Cibulskis, Andrew Kernytsky, Kiran Garimella, David Altshuler, Stacey Gabriel, Mark Daly, Mark A DePristo | Genome Res | 2010 | 20644199 | Yes |
1916 | 3158 | 1579.0 | 67.96 | 34.0 | Microtubules as a target for anticancer drugs. | Mary Ann Jordan, Leslie Wilson | Nat Rev Cancer | 2004 | 15057285 | No |
1917 | 1579 | 1579.0 | 42.52 | 42.5 | Stress and depression. | Constance Hammen | Annu Rev Clin Psychol | 2005 | 17716090 | No |
1918 | 3156 | 1578.0 | 76.42 | 38.2 | Steatohepatitis: a tale of two "hits"? | C P Day, O F James | Gastroenterology | 1998 | 9547102 | No |
1919 | 3155 | 1577.5 | 94.83 | 47.4 | CTFFIND4: Fast and accurate defocus estimation from electron micrographs. | Alexis Rohou, Nikolaus Grigorieff | J Struct Biol | 2015 | 26278980 | Yes |
1920 | 1577 | 1577.0 | 29.67 | 29.7 | Protein degradation and protection against misfolded or damaged proteins. | Alfred L Goldberg | Nature | 2003 | 14685250 | No |
1921 | 3154 | 1577.0 | 74.26 | 37.1 | Malignant gliomas in adults. | Patrick Y Wen, Santosh Kesari | N Engl J Med | 2008 | 18669428 | No |
1922 | 1577 | 1577.0 | 66.18 | 66.2 | Periodontitis: from microbial immune subversion to systemic inflammation. | George Hajishengallis | Nat Rev Immunol | 2015 | 25534621 | No |
1923 | 3153 | 1576.5 | 81.39 | 40.7 | Improvement of phylogenies after removing divergent and ambiguously aligned blocks from protein sequence alignments. | Gerard Talavera, Jose Castresana | Syst Biol | 2007 | 17654362 | Yes |
1924 | 3152 | 1576.0 | 57.65 | 28.8 | The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. | Michael H Glickman, Aaron Ciechanover | Physiol Rev | 2002 | 11917093 | No |
1925 | 3152 | 1576.0 | 81.94 | 41.0 | The gut microbiota shapes intestinal immune responses during health and disease. | June L Round, Sarkis K Mazmanian | Nat Rev Immunol | 2009 | 19343057 | No |
1926 | 3152 | 1576.0 | 76.62 | 38.3 | Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications. | Felix Krueger, Simon R Andrews | Bioinformatics | 2011 | 21493656 | Yes |
1927 | 1575 | 1575.0 | 52.66 | 52.7 | Biology of interleukin 1. | C A Dinarello | FASEB J | 1988 | 3277884 | No |
1928 | 1575 | 1575.0 | 26.02 | 26.0 | Neuronal specification in the spinal cord: inductive signals and transcriptional codes. | T M Jessell | Nat Rev Genet | 2000 | 11262869 | No |
1929 | 1575 | 1575.0 | 33.29 | 33.3 | Tumor metastasis: mechanistic insights and clinical challenges. | Patricia S Steeg | Nat Med | 2006 | 16892035 | No |
1930 | 3149 | 1574.5 | 66.77 | 33.4 | Cancer metastasis: building a framework. | Gaorav P Gupta, Joan Massagué | Cell | 2006 | 17110329 | No |
1931 | 3147 | 1573.5 | 101.22 | 50.6 | The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today. | R Doll, R Peto | J Natl Cancer Inst | 1981 | 7017215 | No |
1932 | 1573 | 1573.0 | 64.65 | 64.7 | Regulation of noradrenaline release by presynaptic receptor systems. | K Starke | Rev Physiol Biochem Pharmacol | 1977 | 14389 | No |
1933 | 1573 | 1573.0 | 27.84 | 27.8 | Selforganization of matter and the evolution of biological macromolecules. | M Eigen | Naturwissenschaften | 1971 | 4942363 | No |
1934 | 1573 | 1573.0 | 41.66 | 41.7 | Molecular bases of the acute coronary syndromes. | P Libby | Circulation | 1995 | 7758192 | No |
1935 | 1573 | 1573.0 | 35.3 | 35.3 | The proto-oncogene Bcl-2 and its role in regulating apoptosis. | G Kroemer | Nat Med | 1997 | 9176486 | No |
1936 | 4718 | 1572.7 | 93.29 | 31.1 | Efficient selection for high-expression transfectants with a novel eukaryotic vector. | H Niwa, K Yamamura, J Miyazaki | Gene | 1991 | 1660837 | Yes |
1937 | 3145 | 1572.5 | 95.12 | 47.6 | Modified RECIST (mRECIST) assessment for hepatocellular carcinoma. | Riccardo Lencioni, Josep M Llovet | Semin Liver Dis | 2010 | 20175033 | No |
1938 | 1572 | 1572.0 | 37.55 | 37.5 | HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy. | J M Coffin | Science | 1995 | 7824947 | Yes |
1939 | 1572 | 1572.0 | 29.54 | 29.5 | Intrinsically unstructured proteins. | Peter Tompa | Trends Biochem Sci | 2002 | 12368089 | No |
1940 | 3143 | 1571.5 | 64.98 | 32.5 | Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome. | C B Lozzio, B B Lozzio | Blood | 1975 | 163658 | Yes |
1941 | 1571 | 1571.0 | 0.0 | 0.0 | A modified spectrophotometric determination of chymotrypsin, trypsin, and thrombin. | B C Hummel | Can J Biochem Physiol | 1959 | 14405350 | Yes |
1942 | 1570 | 1570.0 | 61.69 | 61.7 | A structured interview guide for the Hamilton Depression Rating Scale. | J B Williams | Arch Gen Psychiatry | 1988 | 3395203 | Yes |
1943 | 1570 | 1570.0 | 44.88 | 44.9 | Glycosphingolipids in cellular interaction, differentiation, and oncogenesis. | S Hakomori | Annu Rev Biochem | 1981 | 7023369 | No |
1944 | 4710 | 1570.0 | 87.61 | 29.2 | Notch signaling: cell fate control and signal integration in development. | S Artavanis-Tsakonas, M D Rand, R J Lake | Science | 1999 | 10221902 | No |
1945 | 3140 | 1570.0 | 78.96 | 39.5 | Dali server: conservation mapping in 3D. | Liisa Holm, Päivi Rosenström | Nucleic Acids Res | 2010 | 20457744 | Yes |
1946 | 1569 | 1569.0 | 33.7 | 33.7 | The tumor microenvironment and its role in promoting tumor growth. | T L Whiteside | Oncogene | 2008 | 18836471 | No |
1947 | 1568 | 1568.0 | 59.3 | 59.3 | Local effector functions of capsaicin-sensitive sensory nerve endings: involvement of tachykinins, calcitonin gene-related peptide and other neuropeptides. | P Holzer | Neuroscience | 1988 | 3288903 | No |
1948 | 3136 | 1568.0 | 122.03 | 61.0 | Assessment of eating disorders: interview or self-report questionnaire? | C G Fairburn, S J Beglin | Int J Eat Disord | 1994 | 7866415 | Yes |
1949 | 1568 | 1568.0 | 38.48 | 38.5 | Use and misuse of the receiver operating characteristic curve in risk prediction. | Nancy R Cook | Circulation | 2007 | 17309939 | Yes |
1950 | 3135 | 1567.5 | 60.31 | 30.2 | Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. | O Tetsu, F McCormick | Nature | 1999 | 10201372 | Yes |
1951 | 3133 | 1566.5 | 107.56 | 53.8 | Diabetes and cardiovascular disease. The Framingham study. | W B Kannel, D L McGee | JAMA | 1979 | 430798 | Yes |
1952 | 4699 | 1566.3 | 227.46 | 75.8 | Shedding light on the cell biology of extracellular vesicles. | Guillaume van Niel, Gisela D'Angelo, Graça Raposo | Nat Rev Mol Cell Biol | 2018 | 29339798 | No |
1953 | 1566 | 1566.0 | 35.12 | 35.1 | Pathogenesis of group A streptococcal infections. | M W Cunningham | Clin Microbiol Rev | 2000 | 10885988 | No |
1954 | 1565 | 1565.0 | 58.76 | 58.8 | Screening for lung cancer: U.S. Preventive Services Task Force recommendation statement. | Virginia A Moyer | Ann Intern Med | 2014 | 24378917 | No |
1955 | 1565 | 1565.0 | 61.51 | 61.5 | The global burden of IBD: from 2015 to 2025. | Gilaad G Kaplan | Nat Rev Gastroenterol Hepatol | 2015 | 26323879 | No |
1956 | 1564 | 1564.0 | 36.43 | 36.4 | The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. | H Maeda | Adv Enzyme Regul | 2001 | 11384745 | No |
1957 | 1563 | 1563.0 | 68.29 | 68.3 | Derivation and validation of a short-form oral health impact profile. | G D Slade | Community Dent Oral Epidemiol | 1997 | 9332805 | Yes |
1958 | 1562 | 1562.0 | 42.91 | 42.9 | Bioactive microbial metabolites. | János Bérdy | J Antibiot (Tokyo) | 2005 | 15813176 | No |
1959 | 1562 | 1562.0 | 43.86 | 43.9 | Surface plasmon resonance sensors for detection of chemical and biological species. | Jirí Homola | Chem Rev | 2008 | 18229953 | No |
1960 | 3123 | 1561.5 | 58.67 | 29.3 | Mutations affecting segment number and polarity in Drosophila. | C Nüsslein-Volhard, E Wieschaus | Nature | 1980 | 6776413 | Yes |
1961 | 15615 | 1561.5 | 371.22 | 37.1 | Multilineage potential of adult human mesenchymal stem cells. | M F Pittenger, A M Mackay, S C Beck, R K Jaiswal, R Douglas, J D Mosca, M A Moorman, D W Simonetti, S Craig, D R Marshak | Science | 1999 | 10102814 | Yes |
1962 | 1561 | 1561.0 | 66.88 | 66.9 | Machine Learning in Medicine. | Rahul C Deo | Circulation | 2015 | 26572668 | No |
1963 | 3121 | 1560.5 | 74.62 | 37.3 | Decision curve analysis: a novel method for evaluating prediction models. | Andrew J Vickers, Elena B Elkin | Med Decis Making | 2006 | 17099194 | Yes |
1964 | 3121 | 1560.5 | 69.01 | 34.5 | The DNA damage response: making it safe to play with knives. | Alberto Ciccia, Stephen J Elledge | Mol Cell | 2010 | 20965415 | No |
1965 | 1560 | 1560.0 | 32.31 | 32.3 | Drug discovery: a historical perspective. | J Drews | Science | 2000 | 10720314 | No |
1966 | 1560 | 1560.0 | 28.74 | 28.7 | Vienna RNA secondary structure server. | Ivo L Hofacker | Nucleic Acids Res | 2003 | 12824340 | Yes |
1967 | 1560 | 1560.0 | 0.0 | 0.0 | The estimation of phosphorus. | R J Allen | Biochem J | 1940 | 16747230 | Yes |
1968 | 1559 | 1559.0 | 48.63 | 48.6 | Evidence for a central component of post-injury pain hypersensitivity. | C J Woolf | Nature | 1983 | 6656869 | Yes |
1969 | 1559 | 1559.0 | 31.27 | 31.3 | The ubiquitin-proteasome proteolytic pathway. | A Ciechanover | Cell | 1994 | 7923371 | No |
1970 | 1559 | 1559.0 | 43.32 | 43.3 | Emotion regulation: affective, cognitive, and social consequences. | James J Gross | Psychophysiology | 2002 | 12212647 | No |
1971 | 3116 | 1558.0 | 66.42 | 33.2 | Self-assembly at all scales. | George M Whitesides, Bartosz Grzybowski | Science | 2002 | 11923529 | Yes |
1972 | 3114 | 1557.0 | 61.94 | 31.0 | Toll-like receptor control of the adaptive immune responses. | Akiko Iwasaki, Ruslan Medzhitov | Nat Immunol | 2004 | 15454922 | No |
1973 | 1557 | 1557.0 | 43.94 | 43.9 | Mitochondria and cancer. | Douglas C Wallace | Nat Rev Cancer | 2012 | 23001348 | No |
1974 | 3113 | 1556.5 | 116.46 | 58.2 | Conn: a functional connectivity toolbox for correlated and anticorrelated brain networks. | Susan Whitfield-Gabrieli, Alfonso Nieto-Castanon | Brain Connect | 2012 | 22642651 | Yes |
1975 | 1556 | 1556.0 | 48.98 | 49.0 | The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate. | G R Buettner | Arch Biochem Biophys | 1993 | 8434935 | No |
1976 | 1555 | 1555.0 | 33.18 | 33.2 | Critical period plasticity in local cortical circuits. | Takao K Hensch | Nat Rev Neurosci | 2005 | 16261181 | No |
1977 | 4663 | 1554.3 | 120.16 | 40.1 | How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. | R M Sapolsky, L M Romero, A U Munck | Endocr Rev | 2000 | 10696570 | No |
1978 | 4660 | 1553.3 | 155.97 | 52.0 | Phylogenetic identification and in situ detection of individual microbial cells without cultivation. | R I Amann, W Ludwig, K H Schleifer | Microbiol Rev | 1995 | 7535888 | No |
1979 | 1553 | 1553.0 | 77.73 | 77.7 | Bias in analytic research. | D L Sackett | J Chronic Dis | 1979 | 447779 | Yes |
1980 | 1553 | 1553.0 | 51.61 | 51.6 | A Social Neuroscience Perspective on Adolescent Risk-Taking. | Laurence Steinberg | Dev Rev | 2008 | 18509515 | Yes |
1981 | 4658 | 1552.7 | 103.39 | 34.5 | Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer. | M A Frohman, M K Dush, G R Martin | Proc Natl Acad Sci U S A | 1988 | 2461560 | Yes |
1982 | 3105 | 1552.5 | 71.7 | 35.9 | A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. | L Buck, R Axel | Cell | 1991 | 1840504 | Yes |
1983 | 1551 | 1551.0 | 36.95 | 37.0 | Myeloperoxidase: friend and foe. | Seymour J Klebanoff | J Leukoc Biol | 2005 | 15689384 | No |
1984 | 1551 | 1551.0 | 60.1 | 60.1 | MorphoJ: an integrated software package for geometric morphometrics. | Christian Peter Klingenberg | Mol Ecol Resour | 2011 | 21429143 | Yes |
1985 | 3101 | 1550.5 | 79.73 | 39.9 | Empirical threshold values for quantitative trait mapping. | G A Churchill, R W Doerge | Genetics | 1994 | 7851788 | Yes |
1986 | 1550 | 1550.0 | 30.11 | 30.1 | Macromolecular crowding: obvious but underappreciated. | R J Ellis | Trends Biochem Sci | 2001 | 11590012 | No |
1987 | 3099 | 1549.5 | 67.08 | 33.5 | Cellular senescence: when bad things happen to good cells. | Judith Campisi, Fabrizio d'Adda di Fagagna | Nat Rev Mol Cell Biol | 2007 | 17667954 | No |
1988 | 4648 | 1549.3 | 131.14 | 43.7 | The fusiform face area: a module in human extrastriate cortex specialized for face perception. | N Kanwisher, J McDermott, M M Chun | J Neurosci | 1997 | 9151747 | Yes |
1989 | 3098 | 1549.0 | 185.2 | 92.6 | A scaled version of the General Health Questionnaire. | D P Goldberg, V F Hillier | Psychol Med | 1979 | 424481 | Yes |
1990 | 3098 | 1549.0 | 56.42 | 28.2 | Cellular motility driven by assembly and disassembly of actin filaments. | Thomas D Pollard, Gary G Borisy | Cell | 2003 | 12600310 | No |
1991 | 1549 | 1549.0 | 0.0 | 0.0 | Nutrition needs of mammalian cells in tissue culture. | H Eagle | Science | 1955 | 13255879 | Yes |
1992 | 7742 | 1548.4 | 152.55 | 30.5 | Prospective identification of tumorigenic breast cancer cells. | Muhammad Al-Hajj, Max S Wicha, Adalberto Benito-Hernandez, Sean J Morrison, Michael F Clarke | Proc Natl Acad Sci U S A | 2003 | 12629218 | Yes |
1993 | 1548 | 1548.0 | 43.9 | 43.9 | Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy. | A E Pegg | Cancer Res | 1988 | 3123052 | No |
1994 | 4644 | 1548.0 | 88.51 | 29.5 | A highly sensitive adenylate cyclase assay. | Y Salomon, C Londos, M Rodbell | Anal Biochem | 1974 | 4827395 | Yes |
1995 | 3096 | 1548.0 | 76.78 | 38.4 | Obesity. | David W Haslam, W Philip T James | Lancet | 2005 | 16198769 | No |
1996 | 1547 | 1547.0 | 43.08 | 43.1 | The glomerular permeability determined by dextran clearance using Sephadex gel filtration. | C E Mogensen | Scand J Clin Lab Invest | 1968 | 5637478 | Yes |
1997 | 3094 | 1547.0 | 103.78 | 51.9 | Van der Waals heterostructures. | A K Geim, I V Grigorieva | Nature | 2013 | 23887427 | Yes |
1998 | 3093 | 1546.5 | 63.59 | 31.8 | Coordination of circadian timing in mammals. | Steven M Reppert, David R Weaver | Nature | 2002 | 12198538 | No |
1999 | 3092 | 1546.0 | 39.94 | 20.0 | Computed circular dichroism spectra for the evaluation of protein conformation. | N Greenfield, G D Fasman | Biochemistry | 1969 | 5346390 | Yes |
2000 | 1546 | 1546.0 | 35.99 | 36.0 | Upconversion and anti-Stokes processes with f and d ions in solids. | François Auzel | Chem Rev | 2004 | 14719973 | Yes |
2001 | 1546 | 1546.0 | 41.82 | 41.8 | n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases. | Philip C Calder | Am J Clin Nutr | 2006 | 16841861 | No |
2002 | 3091 | 1545.5 | 61.93 | 31.0 | The Bcl2 family: regulators of the cellular life-or-death switch. | Suzanne Cory, Jerry M Adams | Nat Rev Cancer | 2002 | 12209154 | No |
2003 | 1544 | 1544.0 | 42.1 | 42.1 | Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum. | A Fabiato | Am J Physiol | 1983 | 6346892 | No |
2004 | 1544 | 1544.0 | 45.18 | 45.2 | Signal transduction by reactive oxygen species. | Toren Finkel | J Cell Biol | 2011 | 21746850 | No |
2005 | 9262 | 1543.7 | 217.03 | 36.2 | Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. | Hadi Valadi, Karin Ekström, Apostolos Bossios, Margareta Sjöstrand, James J Lee, Jan O Lötvall | Nat Cell Biol | 2007 | 17486113 | Yes |
2006 | 1543 | 1543.0 | 51.08 | 51.1 | Deliberate practice and the acquisition and maintenance of expert performance in medicine and related domains. | K Anders Ericsson | Acad Med | 2004 | 15383395 | No |
2007 | 4627 | 1542.3 | 112.11 | 37.4 | Membrane lipids: where they are and how they behave. | Gerrit van Meer, Dennis R Voelker, Gerald W Feigenson | Nat Rev Mol Cell Biol | 2008 | 18216768 | No |
2008 | 1542 | 1542.0 | 53.14 | 53.1 | Biological applications of ionophores. | B C Pressman | Annu Rev Biochem | 1976 | 786156 | No |
2009 | 4626 | 1542.0 | 127.18 | 42.4 | Cell death: the significance of apoptosis. | A H Wyllie, J F Kerr, A R Currie | Int Rev Cytol | 1980 | 7014501 | No |
2010 | 4625 | 1541.7 | 117.97 | 39.3 | Cortical surface-based analysis. II: Inflation, flattening, and a surface-based coordinate system. | B Fischl, M I Sereno, A M Dale | Neuroimage | 1999 | 9931269 | Yes |
2011 | 1540 | 1540.0 | 30.7 | 30.7 | RNA silencing in plants. | David Baulcombe | Nature | 2004 | 15372043 | No |
2012 | 4619 | 1539.7 | 99.57 | 33.2 | Osteoclast differentiation and activation. | William J Boyle, W Scott Simonet, David L Lacey | Nature | 2003 | 12748652 | No |
2013 | 1539 | 1539.0 | 43.43 | 43.4 | Glycobiology: Toward Understanding the Function of Sugars. | Raymond A. Dwek | Chem Rev | 1996 | 11848770 | Yes |
2014 | 1537 | 1537.0 | 49.12 | 49.1 | Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. | C A Barnes | J Comp Physiol Psychol | 1979 | 221551 | Yes |
2015 | 3074 | 1537.0 | 71.23 | 35.6 | New Giemsa method for the differential staining of sister chromatids. | P Perry, S Wolff | Nature | 1974 | 4138930 | Yes |
2016 | 1537 | 1537.0 | 47.75 | 47.8 | The Neuropsychiatric Inventory: assessing psychopathology in dementia patients. | J L Cummings | Neurology | 1997 | 9153155 | No |
2017 | 3074 | 1537.0 | 87.94 | 44.0 | What's the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes. | J Zhang, K F Yu | JAMA | 1998 | 9832001 | Yes |
2018 | 6148 | 1537.0 | 119.18 | 29.8 | A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. | B M Bolstad, R A Irizarry, M Astrand, T P Speed | Bioinformatics | 2003 | 12538238 | Yes |
2019 | 3074 | 1537.0 | 0.0 | 0.0 | A method for the determination of desoxyribonucleic acid, ribonucleic acid, and phosphoproteins in animal tissues. | G Schmidt, S J Thannhauser | J Biol Chem | 1945 | 21005717 | Yes |
2020 | 4610 | 1536.7 | 52.14 | 17.4 | Improved method for the determination of blood glutathione. | E Beutler, O Duron, B M Kelly | J Lab Clin Med | 1963 | 13967893 | Yes |
2021 | 3073 | 1536.5 | 21.6 | 10.8 | Junctional complexes in various epithelia. | M G Farquhar, G E Palade | J Cell Biol | 1963 | 13944428 | Yes |
2022 | 9214 | 1535.7 | 281.24 | 46.9 | TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. | Daehwan Kim, Geo Pertea, Cole Trapnell, Harold Pimentel, Ryan Kelley, Steven L Salzberg | Genome Biol | 2013 | 23618408 | Yes |
2023 | 3071 | 1535.5 | 79.15 | 39.6 | Lipid rafts as a membrane-organizing principle. | Daniel Lingwood, Kai Simons | Science | 2010 | 20044567 | No |
2024 | 1535 | 1535.0 | 67.51 | 67.5 | Human agency in social cognitive theory. | A Bandura | Am Psychol | 1989 | 2782727 | Yes |
2025 | 3070 | 1535.0 | 89.16 | 44.6 | Mediation in experimental and nonexperimental studies: new procedures and recommendations. | Patrick E Shrout, Niall Bolger | Psychol Methods | 2002 | 12530702 | Yes |
2026 | 3068 | 1534.0 | 62.19 | 31.1 | Development by self-digestion: molecular mechanisms and biological functions of autophagy. | Beth Levine, Daniel J Klionsky | Dev Cell | 2004 | 15068787 | No |
2027 | 1533 | 1533.0 | 45.73 | 45.7 | Recent advances in the biochemistry of polyamines in eukaryotes. | A E Pegg | Biochem J | 1986 | 3087344 | No |
2028 | 1533 | 1533.0 | 37.97 | 38.0 | Type I diabetes mellitus. A chronic autoimmune disease. | G S Eisenbarth | N Engl J Med | 1986 | 3517648 | No |
2029 | 3065 | 1532.5 | 67.76 | 33.9 | NF-kappaB: a key role in inflammatory diseases. | P P Tak, G S Firestein | J Clin Invest | 2001 | 11134171 | No |
2030 | 1532 | 1532.0 | 30.08 | 30.1 | E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. | J R Nevins | Science | 1992 | 1411535 | Yes |
2031 | 1532 | 1532.0 | 48.79 | 48.8 | Inflammation in atherosclerosis. | Peter Libby | Arterioscler Thromb Vasc Biol | 2012 | 22895665 | No |
2032 | 1531 | 1531.0 | 50.1 | 50.1 | The measurement of psychological androgyny. | S L Bem | J Consult Clin Psychol | 1974 | 4823550 | Yes |
2033 | 1531 | 1531.0 | 43.07 | 43.1 | The Hospital Anxiety And Depression Scale. | R Philip Snaith | Health Qual Life Outcomes | 2003 | 12914662 | Yes |
2034 | 3059 | 1529.5 | 67.18 | 33.6 | Cell migration: a physically integrated molecular process. | D A Lauffenburger, A F Horwitz | Cell | 1996 | 8608589 | No |
2035 | 1529 | 1529.0 | 56.38 | 56.4 | Statistical analysis of enzyme kinetic data. | W W Cleland | Methods Enzymol | 1979 | 502857 | Yes |
2036 | 1528 | 1528.0 | 33.69 | 33.7 | Molecular themes in oncogenesis. | J M Bishop | Cell | 1991 | 1988146 | No |
2037 | 1528 | 1528.0 | 41.24 | 41.2 | Tumor invasion and metastases--role of the extracellular matrix: Rhoads Memorial Award lecture. | L A Liotta | Cancer Res | 1986 | 2998604 | No |
2038 | 1528 | 1528.0 | 22.23 | 22.2 | An enzymic method for the trace iodination of immunoglobulins and other proteins. | J J Marchalonis | Biochem J | 1969 | 4185494 | Yes |
2039 | 1528 | 1528.0 | 52.02 | 52.0 | Assessing self-maintenance: activities of daily living, mobility, and instrumental activities of daily living. | S Katz | J Am Geriatr Soc | 1983 | 6418786 | No |
2040 | 1528 | 1528.0 | 38.45 | 38.5 | Interoception: the sense of the physiological condition of the body. | A D Craig | Curr Opin Neurobiol | 2003 | 12965300 | No |
2041 | 1528 | 1528.0 | 31.38 | 31.4 | Antigen-Antibody Crossed Electrophoresis. | C B Laurell | Anal Biochem | 1965 | 14302464 | Yes |
2042 | 3056 | 1528.0 | 83.09 | 41.5 | Genome regulation by long noncoding RNAs. | John L Rinn, Howard Y Chang | Annu Rev Biochem | 2012 | 22663078 | No |
2043 | 3055 | 1527.5 | 62.69 | 31.3 | Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry. | Joshua E Elias, Steven P Gygi | Nat Methods | 2007 | 17327847 | Yes |
2044 | 1527 | 1527.0 | 42.46 | 42.5 | Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy. | Y Ben-Ari | Neuroscience | 1985 | 2859548 | No |
2045 | 1527 | 1527.0 | 38.57 | 38.6 | Dopamine (3-hydroxytyramine) and brain function. | O Hornykiewicz | Pharmacol Rev | 1966 | 5328389 | No |
2046 | 1527 | 1527.0 | 49.63 | 49.6 | The World Oral Health Report 2003: continuous improvement of oral health in the 21st century--the approach of the WHO Global Oral Health Programme. | Poul Erik Petersen | Community Dent Oral Epidemiol | 2003 | 15015736 | Yes |
2047 | 1526 | 1526.0 | 34.53 | 34.5 | Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study). | K M Fox | Lancet | 2003 | 13678872 | Yes |
2048 | 4575 | 1525.0 | 158.43 | 52.8 | CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. | Teresa C Horan, Mary Andrus, Margaret A Dudeck | Am J Infect Control | 2008 | 18538699 | No |
2049 | 3050 | 1525.0 | 116.65 | 58.3 | Cisplatin in cancer therapy: molecular mechanisms of action. | Shaloam Dasari, Paul Bernard Tchounwou | Eur J Pharmacol | 2014 | 25058905 | No |
2050 | 3049 | 1524.5 | 70.9 | 35.5 | Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. | F Q Schafer, G R Buettner | Free Radic Biol Med | 2001 | 11368918 | No |
2051 | 1524 | 1524.0 | 38.79 | 38.8 | Early signals in the mitogenic response. | E Rozengurt | Science | 1986 | 3018928 | No |
2052 | 1524 | 1524.0 | 18.72 | 18.7 | A soluble protein characteristic of the nervous system. | B W Moore | Biochem Biophys Res Commun | 1965 | 4953930 | Yes |
2053 | 1524 | 1524.0 | 45.86 | 45.9 | Domino Reactions in Organic Synthesis. | Lutz F. Tietze | Chem Rev | 1996 | 11848746 | Yes |
2054 | 1524 | 1524.0 | 33.17 | 33.2 | Far-field optical nanoscopy. | Stefan W Hell | Science | 2007 | 17525330 | No |
2055 | 1523 | 1523.0 | 49.58 | 49.6 | Some observations upon a new inhibitor of monoamine oxidase in brain tissue. | J P Johnston | Biochem Pharmacol | 1968 | 5659776 | Yes |
2056 | 3045 | 1522.5 | 79.81 | 39.9 | Materials for electrochemical capacitors. | Patrice Simon, Yury Gogotsi | Nat Mater | 2008 | 18956000 | Yes |
2057 | 1521 | 1521.0 | 45.31 | 45.3 | Calcium release from the sarcoplasmic reticulum. | M Endo | Physiol Rev | 1977 | 13441 | Yes |
2058 | 4563 | 1521.0 | 96.03 | 32.0 | The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. | S K Hanks, A M Quinn, T Hunter | Science | 1988 | 3291115 | No |
2059 | 1520 | 1520.0 | 56.02 | 56.0 | Atherogenesis: a postprandial phenomenon. | D B Zilversmit | Circulation | 1979 | 222498 | Yes |
2060 | 1520 | 1520.0 | 33.44 | 33.4 | Ordered porous materials for emerging applications. | Mark E Davis | Nature | 2002 | 12075343 | No |
2061 | 1520 | 1520.0 | 0.0 | 0.0 | A new readability yardstick. | R Flesch | J Appl Psychol | 1948 | 18867058 | Yes |
2062 | 1519 | 1519.0 | 91.58 | 91.6 | Stimulated acoustic emissions from within the human auditory system. | D T Kemp | J Acoust Soc Am | 1978 | 744838 | Yes |
2063 | 4555 | 1518.3 | 131.91 | 44.0 | Validation of the Insomnia Severity Index as an outcome measure for insomnia research. | C H. Bastien, A Vallières, C M. Morin | Sleep Med | 2001 | 11438246 | Yes |
2064 | 1518 | 1518.0 | 38.02 | 38.0 | Trophic factors and neuronal survival. | Y A Barde | Neuron | 1989 | 2697237 | No |
2065 | 3036 | 1518.0 | 76.92 | 38.5 | Abdominal obesity and metabolic syndrome. | Jean-Pierre Després, Isabelle Lemieux | Nature | 2006 | 17167477 | No |
2066 | 1517 | 1517.0 | 31.86 | 31.9 | Topoisomerase I inhibitors: camptothecins and beyond. | Yves Pommier | Nat Rev Cancer | 2006 | 16990856 | No |
2067 | 1516 | 1516.0 | 44.16 | 44.2 | The fetal and infant origins of adult disease. | D J Barker | BMJ | 1990 | 2252919 | No |
2068 | 1516 | 1516.0 | 31.6 | 31.6 | Cancer epigenomics: DNA methylomes and histone-modification maps. | Manel Esteller | Nat Rev Genet | 2007 | 17339880 | No |
2069 | 1514 | 1514.0 | 39.93 | 39.9 | Reversible binding of Pi by beef heart mitochondrial adenosine triphosphatase. | H S Penefsky | J Biol Chem | 1977 | 16006 | Yes |
2070 | 1514 | 1514.0 | 27.89 | 27.9 | Aggresomes, inclusion bodies and protein aggregation. | R R Kopito | Trends Cell Biol | 2000 | 11121744 | No |
2071 | 1513 | 1513.0 | 50.26 | 50.3 | Stereology of arbitrary particles. A review of unbiased number and size estimators and the presentation of some new ones, in memory of William R. Thompson. | H J Gundersen | J Microsc | 1986 | 3761363 | Yes |
2072 | 1513 | 1513.0 | 48.16 | 48.2 | Health consequences of obesity in youth: childhood predictors of adult disease. | W H Dietz | Pediatrics | 1998 | 12224658 | No |
2073 | 1513 | 1513.0 | 36.72 | 36.7 | Fast and robust fixed-point algorithms for independent component analysis. | A Hyvärinen | IEEE Trans Neural Netw | 1999 | 18252563 | Yes |
2074 | 19668 | 1512.9 | 508.22 | 39.1 | Clustal W and Clustal X version 2.0. | M A Larkin, G Blackshields, N P Brown, R Chenna, P A McGettigan, H McWilliam, F Valentin, I M Wallace, A Wilm, R Lopez, J D Thompson, T J Gibson, D G Higgins | Bioinformatics | 2007 | 17846036 | Yes |
2075 | 4531 | 1510.3 | 120.12 | 40.0 | I-TASSER: a unified platform for automated protein structure and function prediction. | Ambrish Roy, Alper Kucukural, Yang Zhang | Nat Protoc | 2010 | 20360767 | Yes |
2076 | 1510 | 1510.0 | 44.15 | 44.1 | Energy contributions of volatile fatty acids from the gastrointestinal tract in various species. | E N Bergman | Physiol Rev | 1990 | 2181501 | No |
2077 | 3020 | 1510.0 | 88.0 | 44.0 | The cortical organization of speech processing. | Gregory Hickok, David Poeppel | Nat Rev Neurosci | 2007 | 17431404 | No |
2078 | 1508 | 1508.0 | 32.79 | 32.8 | The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes. | S E Kahn | Diabetologia | 2003 | 12637977 | No |
2079 | 4522 | 1507.3 | 112.5 | 37.5 | The metabolic syndrome. | Robert H Eckel, Scott M Grundy, Paul Z Zimmet | Lancet | 2005 | 15836891 | No |
2080 | 1507 | 1507.0 | 48.22 | 48.2 | SPSS and SAS programs for determining the number of components using parallel analysis and velicer's MAP test. | B P O'Connor | Behav Res Methods Instrum Comput | 2000 | 11029811 | Yes |
2081 | 3012 | 1506.0 | 58.94 | 29.5 | Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. | P J Mitchell, R Tjian | Science | 1989 | 2667136 | No |
2082 | 1506 | 1506.0 | 59.5 | 59.5 | An outpatient program in behavioral medicine for chronic pain patients based on the practice of mindfulness meditation: theoretical considerations and preliminary results. | J Kabat-Zinn | Gen Hosp Psychiatry | 1982 | 7042457 | Yes |
2083 | 1506 | 1506.0 | 36.96 | 37.0 | Reconciling the chemistry and biology of reactive oxygen species. | Christine C Winterbourn | Nat Chem Biol | 2008 | 18421291 | No |
2084 | 4515 | 1505.0 | 162.63 | 54.2 | Hydroperoxide metabolism in mammalian organs. | B Chance, H Sies, A Boveris | Physiol Rev | 1979 | 37532 | Yes |
2085 | 1505 | 1505.0 | 33.42 | 33.4 | The molecular logic of endocannabinoid signalling. | Daniele Piomelli | Nat Rev Neurosci | 2003 | 14595399 | No |
2086 | 1505 | 1505.0 | 32.95 | 33.0 | Hyaluronan: from extracellular glue to pericellular cue. | Bryan P Toole | Nat Rev Cancer | 2004 | 15229478 | No |
2087 | 1504 | 1504.0 | 26.51 | 26.5 | R factor transfer in Rhizobium leguminosarum. | J E Beringer | J Gen Microbiol | 1974 | 4612098 | Yes |
2088 | 3007 | 1503.5 | 66.44 | 33.2 | How matrix metalloproteinases regulate cell behavior. | M D Sternlicht, Z Werb | Annu Rev Cell Dev Biol | 2001 | 11687497 | No |
2089 | 3007 | 1503.5 | 88.82 | 44.4 | Porosity of 3D biomaterial scaffolds and osteogenesis. | Vassilis Karageorgiou, David Kaplan | Biomaterials | 2005 | 15860204 | No |
2090 | 1503 | 1503.0 | 77.55 | 77.5 | The determinants of parenting: a process model. | J Belsky | Child Dev | 1984 | 6705636 | Yes |
2091 | 1503 | 1503.0 | 61.86 | 61.9 | Receiver Operating Characteristic (ROC) Curve Analysis for Medical Diagnostic Test Evaluation. | Karimollah Hajian-Tilaki | Caspian J Intern Med | 2013 | 24009950 | No |
2092 | 3005 | 1502.5 | 0.0 | 0.0 | Mutations of Bacteria from Virus Sensitivity to Virus Resistance. | S E Luria, M Delbrück | Genetics | 1943 | 17247100 | Yes |
2093 | 1502 | 1502.0 | 40.81 | 40.8 | Rheumatoid arthritis. Pathophysiology and implications for therapy. | E D Harris | N Engl J Med | 1990 | 2271017 | No |
2094 | 1502 | 1502.0 | 52.36 | 52.4 | Lyme disease. | A C Steere | N Engl J Med | 1989 | 2668764 | No |
2095 | 1502 | 1502.0 | 60.49 | 60.5 | Working memory: theories, models, and controversies. | Alan Baddeley | Annu Rev Psychol | 2012 | 21961947 | No |
2096 | 3003 | 1501.5 | 60.02 | 30.0 | Chemokines: a new classification system and their role in immunity. | A Zlotnik, O Yoshie | Immunity | 2000 | 10714678 | No |
2097 | 1501 | 1501.0 | 42.53 | 42.5 | Isolated removal of hypothalamic or other brain nuclei of the rat. | M Palkovits | Brain Res | 1973 | 4747772 | Yes |
2098 | 1500 | 1500.0 | 25.42 | 25.4 | Evidence For The Existence Of Monoamine Neurons In The Central Nervous System. Iv. Distribution Of Monoamine Nerve Terminals In The Central Nervous System. | K Fuxe | Acta Physiol Scand Suppl | 1965 | 14319769 | Yes |
2099 | 1499 | 1499.0 | 33.66 | 33.7 | Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone. | M B Luskin | Neuron | 1993 | 8338665 | Yes |
2100 | 1499 | 1499.0 | 37.22 | 37.2 | An economic method for the fluorescent labeling of PCR fragments. | M Schuelke | Nat Biotechnol | 2000 | 10657137 | Yes |
2101 | 1499 | 1499.0 | 0.0 | 0.0 | The colorimetric determination of phosphorus. | E J King | Biochem J | 1932 | 16744823 | Yes |
2102 | 10490 | 1498.6 | 223.25 | 31.9 | Embryonic stem cell lines derived from human blastocysts. | J A Thomson, J Itskovitz-Eldor, S S Shapiro, M A Waknitz, J J Swiergiel, V S Marshall, J M Jones | Science | 1998 | 9804556 | Yes |
2103 | 2996 | 1498.0 | 0.0 | 0.0 | Lactic dehydrogenase activity in blood. | F Wroblewski, J S Ladue | Proc Soc Exp Biol Med | 1955 | 13273400 | Yes |
2104 | 1497 | 1497.0 | 55.22 | 55.2 | Cardiac valve surgery--the "French correction". | A Carpentier | J Thorac Cardiovasc Surg | 1983 | 6887954 | Yes |
2105 | 2993 | 1496.5 | 101.12 | 50.6 | Thermodynamics of protein association reactions: forces contributing to stability. | P D Ross, S Subramanian | Biochemistry | 1981 | 7248271 | Yes |
2106 | 2993 | 1496.5 | 64.21 | 32.1 | Escaping free-energy minima. | Alessandro Laio, Michele Parrinello | Proc Natl Acad Sci U S A | 2002 | 12271136 | Yes |
2107 | 1496 | 1496.0 | 35.46 | 35.5 | Neuronal synchrony: a versatile code for the definition of relations? | W Singer | Neuron | 1999 | 10677026 | No |
2108 | 1495 | 1495.0 | 47.93 | 47.9 | Stability of proteins: small globular proteins. | P L Privalov | Adv Protein Chem | 1979 | 44431 | No |
2109 | 1495 | 1495.0 | 26.19 | 26.2 | Histone acetylation and transcriptional regulatory mechanisms. | K Struhl | Genes Dev | 1998 | 9499396 | No |
2110 | 1495 | 1495.0 | 70.81 | 70.8 | Chronic illness as biographical disruption. | M Bury | Sociol Health Illn | 1982 | 10260456 | Yes |
2111 | 5980 | 1495.0 | 130.12 | 32.5 | Probability-based protein identification by searching sequence databases using mass spectrometry data. | D N Perkins, D J Pappin, D M Creasy, J S Cottrell | Electrophoresis | 1999 | 10612281 | Yes |
2112 | 1493 | 1493.0 | 33.09 | 33.1 | Tumor suppressor genes. | R A Weinberg | Science | 1991 | 1659741 | No |
2113 | 1492 | 1492.0 | 46.15 | 46.1 | Amino acids: metabolism, functions, and nutrition. | Guoyao Wu | Amino Acids | 2009 | 19301095 | No |
2114 | 2984 | 1492.0 | 74.97 | 37.5 | Molecular replacement with MOLREP. | Alexei Vagin, Alexei Teplyakov | Acta Crystallogr D Biol Crystallogr | 2010 | 20057045 | Yes |
2115 | 1491 | 1491.0 | 46.5 | 46.5 | Polycystic ovary syndrome. | S Franks | N Engl J Med | 1995 | 7651477 | No |
2116 | 2982 | 1491.0 | 87.81 | 43.9 | From best evidence to best practice: effective implementation of change in patients' care. | Richard Grol, Jeremy Grimshaw | Lancet | 2003 | 14568747 | No |
2117 | 1491 | 1491.0 | 0.0 | 0.0 | Notes on continuous stochastic phenomena. | P A P Moran | Biometrika | 1950 | 15420245 | Yes |
2118 | 2982 | 1491.0 | 107.19 | 53.6 | A new initiative on precision medicine. | Francis S Collins, Harold Varmus | N Engl J Med | 2015 | 25635347 | Yes |
2119 | 2981 | 1490.5 | 56.83 | 28.4 | Missing pieces in the NF-kappaB puzzle. | Sankar Ghosh, Michael Karin | Cell | 2002 | 11983155 | No |
2120 | 7452 | 1490.4 | 330.16 | 66.0 | BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs. | Felipe A Simão, Robert M Waterhouse, Panagiotis Ioannidis, Evgenia V Kriventseva, Evgeny M Zdobnov | Bioinformatics | 2015 | 26059717 | Yes |
2121 | 1489 | 1489.0 | 39.11 | 39.1 | The human immunodeficiency virus: infectivity and mechanisms of pathogenesis. | A S Fauci | Science | 1988 | 3277274 | No |
2122 | 1488 | 1488.0 | 43.21 | 43.2 | Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. | M D Maines | FASEB J | 1988 | 3290025 | No |
2123 | 4463 | 1487.7 | 93.58 | 31.2 | TOR signaling in growth and metabolism. | Stephan Wullschleger, Robbie Loewith, Michael N Hall | Cell | 2006 | 16469695 | No |
2124 | 1487 | 1487.0 | 36.78 | 36.8 | Wound healing and its impairment in the diabetic foot. | Vincent Falanga | Lancet | 2005 | 16291068 | No |
2125 | 2974 | 1487.0 | 99.09 | 49.5 | How useful is SBF in predicting in vivo bone bioactivity? | Tadashi Kokubo, Hiroaki Takadama | Biomaterials | 2006 | 16448693 | No |
2126 | 1486 | 1486.0 | 31.64 | 31.6 | Autophagy: from phenomenology to molecular understanding in less than a decade. | Daniel J Klionsky | Nat Rev Mol Cell Biol | 2007 | 17712358 | No |
2127 | 1486 | 1486.0 | 65.64 | 65.6 | Oxidative stress: a concept in redox biology and medicine. | Helmut Sies | Redox Biol | 2015 | 25588755 | No |
2128 | 1485 | 1485.0 | 34.15 | 34.1 | Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors. | J C Unkeless | J Exp Med | 1979 | 90108 | Yes |
2129 | 1485 | 1485.0 | 7.93 | 7.9 | Chemoaffinity In The Orderly Growth Of Nerve Fiber Patterns And Connections. | R W Sperry | Proc Natl Acad Sci U S A | 1963 | 14077501 | Yes |
2130 | 13364 | 1484.9 | 616.73 | 68.5 | Cancer statistics in China, 2015. | Wanqing Chen, Rongshou Zheng, Peter D Baade, Siwei Zhang, Hongmei Zeng, Freddie Bray, Ahmedin Jemal, Xue Qin Yu, Jie He | CA Cancer J Clin | 2016 | 26808342 | Yes |
2131 | 4454 | 1484.7 | 135.29 | 45.1 | Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. | S van der Linden, H A Valkenburg, A Cats | Arthritis Rheum | 1984 | 6231933 | Yes |
2132 | 1484 | 1484.0 | 18.48 | 18.5 | The mechanism of muscular contraction. | H E Huxley | Science | 1969 | 4181952 | No |
2133 | 2968 | 1484.0 | 89.07 | 44.5 | Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI. | P J Basser, C Pierpaoli | J Magn Reson B | 1996 | 8661285 | Yes |
2134 | 1484 | 1484.0 | 65.63 | 65.6 | Mechanisms linking social ties and support to physical and mental health. | Peggy A Thoits | J Health Soc Behav | 2011 | 21673143 | No |
2135 | 1483 | 1483.0 | 19.77 | 19.8 | Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate. | J W Olney | Science | 1969 | 5778021 | Yes |
2136 | 1483 | 1483.0 | 33.22 | 33.2 | Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis. | C Taswell | J Immunol | 1981 | 7009746 | Yes |
2137 | 1482 | 1482.0 | 27.35 | 27.4 | Coupling of enzymes to proteins with glutaraldehyde. Use of the conjugates for the detection of antigens and antibodies. | S Avrameas | Immunochemistry | 1969 | 4975324 | Yes |
2138 | 1482 | 1482.0 | 33.89 | 33.9 | Nonaqueous liquid electrolytes for lithium-based rechargeable batteries. | Kang Xu | Chem Rev | 2004 | 15669157 | Yes |
2139 | 4444 | 1481.3 | 255.65 | 85.2 | Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs. | C A Winter, E A Risley, G W Nuss | Proc Soc Exp Biol Med | 1962 | 14001233 | Yes |
2140 | 1481 | 1481.0 | 21.92 | 21.9 | Codon--anticodon pairing: the wobble hypothesis. | F H Crick | J Mol Biol | 1966 | 5969078 | Yes |
2141 | 1481 | 1481.0 | 0.0 | 0.0 | The Function Of The Vertebral Veins And Their Role In The Spread Of Metastases. | O V Batson | Ann Surg | 1940 | 17857618 | Yes |
2142 | 2962 | 1481.0 | 120.28 | 60.1 | 3D bioprinting of tissues and organs. | Sean V Murphy, Anthony Atala | Nat Biotechnol | 2014 | 25093879 | Yes |
2143 | 1481 | 1481.0 | 41.43 | 41.4 | BEDTools: The Swiss-Army Tool for Genome Feature Analysis. | Aaron R Quinlan | Curr Protoc Bioinformatics | 2014 | 25199790 | Yes |
2144 | 5923 | 1480.8 | 215.21 | 53.8 | FieldTrip: Open source software for advanced analysis of MEG, EEG, and invasive electrophysiological data. | Robert Oostenveld, Pascal Fries, Eric Maris, Jan-Mathijs Schoffelen | Comput Intell Neurosci | 2011 | 21253357 | Yes |
2145 | 4442 | 1480.7 | 45.69 | 15.2 | The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes. | J T Dodge, C Mitchell, D J Hanahan | Arch Biochem Biophys | 1963 | 14028302 | Yes |
2146 | 1480 | 1480.0 | 36.78 | 36.8 | The 'effective number of codons' used in a gene. | F Wright | Gene | 1990 | 2110097 | Yes |
2147 | 1480 | 1480.0 | 45.35 | 45.4 | Equipoise and the ethics of clinical research. | B Freedman | N Engl J Med | 1987 | 3600702 | Yes |
2148 | 1480 | 1480.0 | 33.52 | 33.5 | Defective repair replication of DNA in xeroderma pigmentosum. | J E Cleaver | Nature | 1968 | 5655953 | Yes |
2149 | 1479 | 1479.0 | 30.72 | 30.7 | Ionic blockage of sodium channels in nerve. | A M Woodhull | J Gen Physiol | 1973 | 4541078 | Yes |
2150 | 2958 | 1479.0 | 74.63 | 37.3 | A globally coherent fingerprint of climate change impacts across natural systems. | Camille Parmesan, Gary Yohe | Nature | 2003 | 12511946 | Yes |
2151 | 1479 | 1479.0 | 43.16 | 43.2 | Variations in patients' adherence to medical recommendations: a quantitative review of 50 years of research. | M Robin DiMatteo | Med Care | 2004 | 15076819 | Yes |
2152 | 8873 | 1478.8 | 258.0 | 43.0 | Cancer statistics, 2009. | Ahmedin Jemal, Rebecca Siegel, Elizabeth Ward, Yongping Hao, Jiaquan Xu, Michael J Thun | CA Cancer J Clin | 2009 | 19474385 | Yes |
2153 | 4436 | 1478.7 | 86.58 | 28.9 | The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. | Fabio Martinon, Kimberly Burns, Jürg Tschopp | Mol Cell | 2002 | 12191486 | Yes |
2154 | 1478 | 1478.0 | 44.43 | 44.4 | Superoxide dismutases. | I Fridovich | Annu Rev Biochem | 1975 | 1094908 | No |
2155 | 1478 | 1478.0 | 39.43 | 39.4 | Redox signaling: nitrosylation and related target interactions of nitric oxide. | J S Stamler | Cell | 1994 | 7923362 | No |
2156 | 1478 | 1478.0 | 42.09 | 42.1 | Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. | Charles A Dinarello | Blood | 2011 | 21304099 | No |
2157 | 5910 | 1477.5 | 246.95 | 61.7 | A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. | M A Markwell, S M Haas, L L Bieber, N E Tolbert | Anal Biochem | 1978 | 98070 | Yes |
2158 | 1477 | 1477.0 | 40.23 | 40.2 | Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms. | J A Beavo | Physiol Rev | 1995 | 7480160 | No |
2159 | 5904 | 1476.0 | 159.48 | 39.9 | Image quality assessment: from error visibility to structural similarity. | Zhou Wang, Alan Conrad Bovik, Hamid Rahim Sheikh, Eero P Simoncelli | IEEE Trans Image Process | 2004 | 15376593 | Yes |
2160 | 2952 | 1476.0 | 74.0 | 37.0 | Morris water maze: procedures for assessing spatial and related forms of learning and memory. | Charles V Vorhees, Michael T Williams | Nat Protoc | 2006 | 17406317 | Yes |
2161 | 1475 | 1475.0 | 33.73 | 33.7 | The cadherins: cell-cell adhesion molecules controlling animal morphogenesis. | M Takeichi | Development | 1988 | 3048970 | No |
2162 | 1475 | 1475.0 | 0.0 | 0.0 | Modality and topographic properties of single neurons of cat's somatic sensory cortex. | V B Mountcastle | J Neurophysiol | 1957 | 13439410 | Yes |
2163 | 1475 | 1475.0 | 38.35 | 38.4 | The world health report 2002 - reducing risks, promoting healthy life. | J J Guilbert | Educ Health (Abingdon) | 2003 | 14741909 | Yes |
2164 | 2950 | 1475.0 | 88.3 | 44.1 | An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. | O Johnell, J A Kanis | Osteoporos Int | 2006 | 16983459 | Yes |
2165 | 1474 | 1474.0 | 36.23 | 36.2 | Microbial ecology of the gastrointestinal tract. | D C Savage | Annu Rev Microbiol | 1977 | 334036 | No |
2166 | 1474 | 1474.0 | 37.35 | 37.4 | Hemispheric asymmetry reduction in older adults: the HAROLD model. | Roberto Cabeza | Psychol Aging | 2002 | 11931290 | No |
2167 | 1473 | 1473.0 | 51.77 | 51.8 | The prevalence of 'alexithymic' characteristics in psychosomatic patients. | P E Sifneos | Psychother Psychosom | 1973 | 4770536 | Yes |
2168 | 4417 | 1472.3 | 137.72 | 45.9 | AChE-stained horizontal sections of the rat brain in stereotaxic coordinates. | G Paxinos, C R Watson, P C Emson | J Neurosci Methods | 1980 | 6110810 | Yes |
2169 | 2944 | 1472.0 | 91.87 | 45.9 | Functional architecture of basal ganglia circuits: neural substrates of parallel processing. | G E Alexander, M D Crutcher | Trends Neurosci | 1990 | 1695401 | No |
2170 | 1472 | 1472.0 | 94.67 | 94.7 | The three column spine and its significance in the classification of acute thoracolumbar spinal injuries. | F Denis | Spine (Phila Pa 1976) | 1983 | 6670016 | Yes |
2171 | 2944 | 1472.0 | 76.43 | 38.2 | The expanding universe of T-cell subsets: Th1, Th2 and more. | T R Mosmann, S Sad | Immunol Today | 1996 | 8820272 | No |
2172 | 1472 | 1472.0 | 12.06 | 12.1 | The Relation Of Recombination To Mutational Advance. | H J Muller | Mutat Res | 1964 | 14195748 | Yes |
2173 | 1472 | 1472.0 | 34.17 | 34.2 | Phytohemagglutinin: an initiator of mitosis in cultures of normal human leukocytes. | P C Nowell | Cancer Res | 1960 | 14427849 | Yes |
2174 | 2943 | 1471.5 | 78.08 | 39.0 | A general method for isolation of high molecular weight DNA from eukaryotes. | N Blin, D W Stafford | Nucleic Acids Res | 1976 | 987581 | Yes |
2175 | 13239 | 1471.0 | 407.25 | 45.2 | The 1982 revised criteria for the classification of systemic lupus erythematosus. | E M Tan, A S Cohen, J F Fries, A T Masi, D J McShane, N F Rothfield, J G Schaller, N Talal, R J Winchester | Arthritis Rheum | 1982 | 7138600 | Yes |
2176 | 1471 | 1471.0 | 10.68 | 10.7 | Electron Microscope Studies On The Structure Of Natural And Synthetic Protein Filaments From Striated Muscle. | H E Huxley | J Mol Biol | 1963 | 14064165 | Yes |
2177 | 1471 | 1471.0 | 40.11 | 40.1 | Leishmaniasis: current situation and new perspectives. | P Desjeux | Comp Immunol Microbiol Infect Dis | 2004 | 15225981 | No |
2178 | 1471 | 1471.0 | 52.09 | 52.1 | Phase retrieval algorithms: a comparison. | J R Fienup | Appl Opt | 1982 | 20396114 | Yes |
2179 | 1470 | 1470.0 | 31.91 | 31.9 | Mitochondria: dynamic organelles in disease, aging, and development. | David C Chan | Cell | 2006 | 16814712 | No |
2180 | 5878 | 1469.5 | 148.76 | 37.2 | Microbial ecology: human gut microbes associated with obesity. | Ruth E Ley, Peter J Turnbaugh, Samuel Klein, Jeffrey I Gordon | Nature | 2006 | 17183309 | Yes |
2181 | 1469 | 1469.0 | 41.13 | 41.1 | Treatment of infections associated with surgical implants. | Rabih O Darouiche | N Engl J Med | 2004 | 15070792 | No |
2182 | 1469 | 1469.0 | 38.3 | 38.3 | Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. | Michael F Holick | Am J Clin Nutr | 2004 | 15585788 | No |
2183 | 1469 | 1469.0 | 34.97 | 35.0 | Origin, biogenesis, and activity of plant microRNAs. | Olivier Voinnet | Cell | 2009 | 19239888 | No |
2184 | 1469 | 1469.0 | 125.55 | 125.5 | The STROBE guidelines. | Sarah Cuschieri | Saudi J Anaesth | 2019 | 30930717 | No |
2185 | 4406 | 1468.7 | 95.55 | 31.8 | Telomeres shorten during ageing of human fibroblasts. | C B Harley, A B Futcher, C W Greider | Nature | 1990 | 2342578 | Yes |
2186 | 2937 | 1468.5 | 155.3 | 77.7 | The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation. | E G Gray, V P Whittaker | J Anat | 1962 | 13901297 | Yes |
2187 | 1467 | 1467.0 | 57.31 | 57.3 | Reliability and factor analysis of the Epworth Sleepiness Scale. | M W Johns | Sleep | 1992 | 1519015 | Yes |
2188 | 2933 | 1466.5 | 57.98 | 29.0 | Intrinsically unstructured proteins and their functions. | H Jane Dyson, Peter E Wright | Nat Rev Mol Cell Biol | 2005 | 15738986 | No |
2189 | 1466 | 1466.0 | 31.73 | 31.7 | DNA damage, aging, and cancer. | Jan H J Hoeijmakers | N Engl J Med | 2009 | 19812404 | No |
2190 | 2930 | 1465.0 | 98.74 | 49.4 | Peptidoglycan types of bacterial cell walls and their taxonomic implications. | K H Schleifer, O Kandler | Bacteriol Rev | 1972 | 4568761 | No |
2191 | 1465 | 1465.0 | 33.53 | 33.5 | Simple methods for "staining with lead" at high pH in electron microscopy. | M J Karnovsky | J Biophys Biochem Cytol | 1961 | 14454024 | Yes |
2192 | 1465 | 1465.0 | 0.0 | 0.0 | The generalisation of student's problems when several different population variances are involved. | B L Welch | Biometrika | 1947 | 20287819 | Yes |
2193 | 2929 | 1464.5 | 94.35 | 47.2 | Synchronization of Plasmodium falciparum erythrocytic stages in culture. | C Lambros, J P Vanderberg | J Parasitol | 1979 | 383936 | Yes |
2194 | 2927 | 1463.5 | 77.5 | 38.8 | Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. | B R Celli, W MacNee | Eur Respir J | 2004 | 15219010 | No |
2195 | 1463 | 1463.0 | 33.79 | 33.8 | PPAR-gamma: adipogenic regulator and thiazolidinedione receptor. | B M Spiegelman | Diabetes | 1998 | 9568680 | No |
2196 | 8778 | 1463.0 | 287.98 | 48.0 | Antioxidant activity applying an improved ABTS radical cation decolorization assay. | R Re, N Pellegrini, A Proteggente, A Pannala, M Yang, C Rice-Evans | Free Radic Biol Med | 1999 | 10381194 | Yes |
2197 | 1463 | 1463.0 | 29.86 | 29.9 | Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. | S S Ferguson | Pharmacol Rev | 2001 | 11171937 | No |
2198 | 1463 | 1463.0 | 35.74 | 35.7 | The amygdala modulates the consolidation of memories of emotionally arousing experiences. | James L McGaugh | Annu Rev Neurosci | 2004 | 15217324 | No |
2199 | 2925 | 1462.5 | 67.74 | 33.9 | The MAPK signaling cascade. | R Seger, E G Krebs | FASEB J | 1995 | 7601337 | No |
2200 | 2925 | 1462.5 | 103.36 | 51.7 | Role of the microbiota in immunity and inflammation. | Yasmine Belkaid, Timothy W Hand | Cell | 2014 | 24679531 | No |
2201 | 11698 | 1462.2 | 290.42 | 36.3 | Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. | N Tzourio-Mazoyer, B Landeau, D Papathanassiou, F Crivello, O Etard, N Delcroix, B Mazoyer, M Joliot | Neuroimage | 2002 | 11771995 | Yes |
2202 | 1462 | 1462.0 | 95.4 | 95.4 | The Knee Society total knee arthroplasty roentgenographic evaluation and scoring system. | F C Ewald | Clin Orthop Relat Res | 1989 | 2805502 | Yes |
2203 | 1462 | 1462.0 | 0.0 | 0.0 | The free amino groups of insulin. | F Sanger | Biochem J | 1945 | 16747948 | Yes |
2204 | 1461 | 1461.0 | 41.49 | 41.5 | The intraclass correlation coefficient as a measure of reliability. | J J Bartko | Psychol Rep | 1966 | 5942109 | Yes |
2205 | 1461 | 1461.0 | 40.67 | 40.7 | Breakthrough of the year 2013. Cancer immunotherapy. | Jennifer Couzin-Frankel | Science | 2013 | 24357284 | No |
2206 | 1460 | 1460.0 | 0.0 | 0.0 | Methods of paper chromatography of steroids applicable to the study of steroids in mammalian blood and tissues. | I E Bush | Biochem J | 1952 | 14915960 | Yes |
2207 | 1459 | 1459.0 | 34.12 | 34.1 | Oxidative stress in Parkinson's disease. | Peter Jenner | Ann Neurol | 2003 | 12666096 | No |
2208 | 1459 | 1459.0 | 43.41 | 43.4 | The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. | Artemis P Simopoulos | Exp Biol Med (Maywood) | 2008 | 18408140 | No |
2209 | 2916 | 1458.0 | 57.78 | 28.9 | Short-term synaptic plasticity. | Robert S Zucker, Wade G Regehr | Annu Rev Physiol | 2002 | 11826273 | No |
2210 | 1458 | 1458.0 | 0.0 | 0.0 | A modified ninhydrin colorimetric analysis for amino acids. | H Rosen | Arch Biochem Biophys | 1957 | 13412116 | Yes |
2211 | 1458 | 1458.0 | 43.73 | 43.7 | The functional gastrointestinal disorders and the Rome III process. | Douglas A Drossman | Gastroenterology | 2006 | 16678553 | No |
2212 | 1457 | 1457.0 | 34.35 | 34.4 | Binary Agrobacterium vectors for plant transformation. | M Bevan | Nucleic Acids Res | 1984 | 6095209 | Yes |
2213 | 2913 | 1456.5 | 73.99 | 37.0 | Alternative activation of macrophages: mechanism and functions. | Siamon Gordon, Fernando O Martinez | Immunity | 2010 | 20510870 | No |
2214 | 2911 | 1455.5 | 75.0 | 37.5 | Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. | I Issemann, S Green | Nature | 1990 | 2129546 | Yes |
2215 | 2910 | 1455.0 | 95.18 | 47.6 | The efficiency of systematic sampling in stereology and its prediction. | H J Gundersen, E B Jensen | J Microsc | 1987 | 3430576 | Yes |
2216 | 1455 | 1455.0 | 47.78 | 47.8 | A clinical method for assessing the ventilatory response to carbon dioxide. | D J Read | Australas Ann Med | 1967 | 6032026 | Yes |
2217 | 2908 | 1454.0 | 99.56 | 49.8 | Assay of proteins in the presence of interfering materials. | A Bensadoun, D Weinstein | Anal Biochem | 1976 | 1259145 | Yes |
2218 | 1454 | 1454.0 | 57.78 | 57.8 | Social phobia. | M R Liebowitz | Mod Probl Pharmacopsychiatry | 1987 | 2885745 | Yes |
2219 | 1454 | 1454.0 | 38.76 | 38.8 | A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE Task Force on Classification and Terminology. | J Engel | Epilepsia | 2001 | 11422340 | Yes |
2220 | 1454 | 1454.0 | 32.72 | 32.7 | Cell signaling. H2O2, a necessary evil for cell signaling. | Sue Goo Rhee | Science | 2006 | 16809515 | Yes |
2221 | 4361 | 1453.7 | 100.6 | 33.5 | Long non-coding RNAs: insights into functions. | Tim R Mercer, Marcel E Dinger, John S Mattick | Nat Rev Genet | 2009 | 19188922 | No |
2222 | 2907 | 1453.5 | 60.39 | 30.2 | The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. | M S Brown, J L Goldstein | Cell | 1997 | 9150132 | No |
2223 | 2905 | 1452.5 | 0.0 | 0.0 | Techniques for hemagglutination and hemagglutination-inhibition with arthropod-borne viruses. | D H Clarke, J Casals | Am J Trop Med Hyg | 1958 | 13571577 | Yes |
2224 | 1451 | 1451.0 | 28.85 | 28.9 | The organization of proteins in the human red blood cell membrane. A review. | T L Steck | J Cell Biol | 1974 | 4600883 | No |
2225 | 1451 | 1451.0 | 31.45 | 31.4 | Protein misfolding, evolution and disease. | C M Dobson | Trends Biochem Sci | 1999 | 10470028 | No |
2226 | 2901 | 1450.5 | 72.56 | 36.3 | 3' non-coding region sequences in eukaryotic messenger RNA. | N J Proudfoot, G G Brownlee | Nature | 1976 | 822353 | Yes |
2227 | 2900 | 1450.0 | 79.52 | 39.8 | A rapid boiling method for the preparation of bacterial plasmids. | D S Holmes, M Quigley | Anal Biochem | 1981 | 6269464 | Yes |
2228 | 4349 | 1449.7 | 87.36 | 29.1 | Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM). | Michael J Rust, Mark Bates, Xiaowei Zhuang | Nat Methods | 2006 | 16896339 | Yes |
2229 | 1449 | 1449.0 | 35.56 | 35.6 | General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids. | R A Houghten | Proc Natl Acad Sci U S A | 1985 | 2410914 | Yes |
2230 | 4347 | 1449.0 | 148.08 | 49.4 | Factor structure of the Barratt impulsiveness scale. | J H Patton, M S Stanford, E S Barratt | J Clin Psychol | 1995 | 8778124 | Yes |
2231 | 4347 | 1449.0 | 92.59 | 30.9 | NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. | S Ghosh, M J May, E B Kopp | Annu Rev Immunol | 1998 | 9597130 | No |
2232 | 2897 | 1448.5 | 55.67 | 27.8 | Autophagy as a regulated pathway of cellular degradation. | D J Klionsky, S D Emr | Science | 2000 | 11099404 | No |
2233 | 1448 | 1448.0 | 33.55 | 33.5 | Developmental cell death: morphological diversity and multiple mechanisms. | P G Clarke | Anat Embryol (Berl) | 1990 | 2186664 | No |
2234 | 1448 | 1448.0 | 48.55 | 48.5 | Gene flow and the geographic structure of natural populations. | M Slatkin | Science | 1987 | 3576198 | Yes |
2235 | 1448 | 1448.0 | 48.5 | 48.5 | Analysis of radioligand binding experiments. A collection of computer programs for the IBM PC. | G A McPherson | J Pharmacol Methods | 1985 | 3840547 | Yes |
2236 | 1448 | 1448.0 | 30.33 | 30.3 | Neurotrophins as synaptic modulators. | M M Poo | Nat Rev Neurosci | 2001 | 11253356 | No |
2237 | 5790 | 1447.5 | 160.38 | 40.1 | The unlabeled antibody enzyme method of immunohistochemistry: preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes. | L A Sternberger, P H Hardy, J J Cuculis, H G Meyer | J Histochem Cytochem | 1970 | 4192899 | Yes |
2238 | 4342 | 1447.3 | 159.14 | 53.0 | Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. | C J Caspersen, K E Powell, G M Christenson | Public Health Rep | 1985 | 3920711 | Yes |
2239 | 1447 | 1447.0 | 36.13 | 36.1 | Stress and hippocampal plasticity. | B S McEwen | Annu Rev Neurosci | 1999 | 10202533 | No |
2240 | 2894 | 1447.0 | 176.12 | 88.1 | A study of the factors affecting the aluminum oxide-trihydroxyindole procedure for the analysis of catecholamines. | A H Anton, D F Sayre | J Pharmacol Exp Ther | 1962 | 14013351 | Yes |
2241 | 2894 | 1447.0 | 0.0 | 0.0 | Brain stem reticular formation and activation of the EEG. | G Moruzzi, H W Magoun | Electroencephalogr Clin Neurophysiol | 1949 | 18421835 | Yes |
2242 | 2893 | 1446.5 | 65.96 | 33.0 | Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA. | C Auffray, F Rougeon | Eur J Biochem | 1980 | 6772444 | Yes |
2243 | 5785 | 1446.2 | 169.09 | 42.3 | Reversible middle cerebral artery occlusion without craniectomy in rats. | E Z Longa, P R Weinstein, S Carlson, R Cummins | Stroke | 1989 | 2643202 | Yes |
2244 | 1446 | 1446.0 | 37.84 | 37.8 | Cell and environment interactions in tumor microregions: the multicell spheroid model. | R M Sutherland | Science | 1988 | 2451290 | Yes |
2245 | 1446 | 1446.0 | 43.77 | 43.8 | Biological basis of the behavior of sick animals. | B L Hart | Neurosci Biobehav Rev | 1988 | 3050629 | No |
2246 | 1446 | 1446.0 | 21.62 | 21.6 | Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis. | K S McCully | Am J Pathol | 1969 | 5792556 | Yes |
2247 | 1446 | 1446.0 | 49.92 | 49.9 | Colorimetric determination of phospholipids with ammonium ferrothiocyanate. | J C Stewart | Anal Biochem | 1980 | 6892980 | Yes |
2248 | 2892 | 1446.0 | 83.83 | 41.9 | Physiological time-series analysis using approximate entropy and sample entropy. | J S Richman, J R Moorman | Am J Physiol Heart Circ Physiol | 2000 | 10843903 | Yes |
2249 | 1446 | 1446.0 | 54.19 | 54.2 | Diversity in tropical rain forests and coral reefs. | J H Connell | Science | 1978 | 17840770 | Yes |
2250 | 2890 | 1445.0 | 73.93 | 37.0 | EasySpin, a comprehensive software package for spectral simulation and analysis in EPR. | Stefan Stoll, Arthur Schweiger | J Magn Reson | 2006 | 16188474 | Yes |
2251 | 1445 | 1445.0 | 58.3 | 58.3 | Transcriptional architecture of the mammalian circadian clock. | Joseph S Takahashi | Nat Rev Genet | 2017 | 27990019 | No |
2252 | 1444 | 1444.0 | 39.62 | 39.6 | Graphene transistors. | Frank Schwierz | Nat Nanotechnol | 2010 | 20512128 | Yes |
2253 | 1444 | 1444.0 | 50.66 | 50.7 | Quantitative Genetic Analysis Of Multivariate Evolution, Applied To Brain:Body Size Allometry. | Russell Lande | Evolution | 1979 | 28568194 | Yes |
2254 | 2887 | 1443.5 | 78.47 | 39.2 | Angiogenesis. | J Folkman, Y Shing | J Biol Chem | 1992 | 1375931 | No |
2255 | 2886 | 1443.0 | 53.84 | 26.9 | T-cell antigen receptor genes and T-cell recognition. | M M Davis, P J Bjorkman | Nature | 1988 | 3043226 | No |
2256 | 2886 | 1443.0 | 0.0 | 0.0 | Mutants of Escherichia coli requiring methionine or vitamin B12. | B D Davis, E S Mingioli | J Bacteriol | 1950 | 15436457 | Yes |
2257 | 2885 | 1442.5 | 67.48 | 33.7 | Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. | H Cai, D G Harrison | Circ Res | 2000 | 11073878 | No |
2258 | 2884 | 1442.0 | 86.01 | 43.0 | The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. | J D Hayes, D J Pulford | Crit Rev Biochem Mol Biol | 1995 | 8770536 | No |
2259 | 1442 | 1442.0 | 34.01 | 34.0 | Proinflammatory cytokines. | C A Dinarello | Chest | 2000 | 10936147 | No |
2260 | 1442 | 1442.0 | 27.59 | 27.6 | The significance of responses of the genome to challenge. | B McClintock | Science | 1984 | 15739260 | No |
2261 | 1440 | 1440.0 | 42.11 | 42.1 | Human cardiovascular adjustments to exercise and thermal stress. | L B Rowell | Physiol Rev | 1974 | 4587247 | No |
2262 | 1440 | 1440.0 | 37.56 | 37.6 | The epidemiology of venous thromboembolism. | Richard H White | Circulation | 2003 | 12814979 | No |
2263 | 1440 | 1440.0 | 0.0 | 0.0 | Potential, Impedance, And Rectification In Membranes. | D E Goldman | J Gen Physiol | 1943 | 19873371 | Yes |
2264 | 1439 | 1439.0 | 37.13 | 37.1 | Capacitative calcium entry revisited. | J W Putney | Cell Calcium | 1990 | 1965707 | No |
2265 | 1439 | 1439.0 | 44.66 | 44.7 | The role of autophagy in neurodegenerative disease. | Ralph A Nixon | Nat Med | 2013 | 23921753 | No |
2266 | 1438 | 1438.0 | 40.1 | 40.1 | Isolation and cultivation of Lyme disease spirochetes. | A G Barbour | Yale J Biol Med | 1984 | 6393604 | Yes |
2267 | 1438 | 1438.0 | 36.14 | 36.1 | Diagnosis of osteoporosis and assessment of fracture risk. | John A Kanis | Lancet | 2002 | 12057569 | No |
2268 | 1437 | 1437.0 | 42.84 | 42.8 | Strong localization of photons in certain disordered dielectric superlattices. | S John | Phys Rev Lett | 1987 | 10034761 | Yes |
2269 | 1437 | 1437.0 | 0.0 | 0.0 | Starch gel electrophoresis in a discontinous system of buffers. | M D Poulik | Nature | 1957 | 13493570 | Yes |
2270 | 4310 | 1436.7 | 122.0 | 40.7 | Dose translation from animal to human studies revisited. | Shannon Reagan-Shaw, Minakshi Nihal, Nihal Ahmad | FASEB J | 2008 | 17942826 | Yes |
2271 | 2870 | 1435.0 | 82.62 | 41.3 | CLUMPP: a cluster matching and permutation program for dealing with label switching and multimodality in analysis of population structure. | Mattias Jakobsson, Noah A Rosenberg | Bioinformatics | 2007 | 17485429 | Yes |
2272 | 1434 | 1434.0 | 60.92 | 60.9 | The self-medication hypothesis of addictive disorders: focus on heroin and cocaine dependence. | E J Khantzian | Am J Psychiatry | 1985 | 3904487 | No |
2273 | 1434 | 1434.0 | 24.83 | 24.8 | The economics of ribosome biosynthesis in yeast. | J R Warner | Trends Biochem Sci | 1999 | 10542411 | No |
2274 | 2867 | 1433.5 | 98.48 | 49.2 | The framing of decisions and the psychology of choice. | A Tversky, D Kahneman | Science | 1981 | 7455683 | Yes |
2275 | 2867 | 1433.5 | 0.0 | 0.0 | Histological grading and prognosis in breast cancer; a study of 1409 cases of which 359 have been followed for 15 years. | H J Bloom, W W Richardson | Br J Cancer | 1957 | 13499785 | Yes |
2276 | 2865 | 1432.5 | 90.94 | 45.5 | Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art. | Johan W S Vlaeyen, Steven J Linton | Pain | 2000 | 10781906 | No |
2277 | 7162 | 1432.4 | 154.28 | 30.9 | Site-directed mutagenesis by overlap extension using the polymerase chain reaction. | S N Ho, H D Hunt, R M Horton, J K Pullen, L R Pease | Gene | 1989 | 2744487 | Yes |
2278 | 2864 | 1432.0 | 96.23 | 48.1 | Selective loss of central cholinergic neurons in Alzheimer's disease. | P Davies, A J Maloney | Lancet | 1976 | 63862 | Yes |
2279 | 1431 | 1431.0 | 45.34 | 45.3 | Antecedent- and response-focused emotion regulation: divergent consequences for experience, expression, and physiology. | J J Gross | J Pers Soc Psychol | 1998 | 9457784 | Yes |
2280 | 2859 | 1429.5 | 70.13 | 35.1 | Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. | E S Lander, D Botstein | Genetics | 1989 | 2563713 | Yes |
2281 | 2858 | 1429.0 | 86.43 | 43.2 | Unidentified curved bacilli on gastric epithelium in active chronic gastritis. | J R Warren, B Marshall | Lancet | 1983 | 6134060 | Yes |
2282 | 1429 | 1429.0 | 39.37 | 39.4 | The debate over dopamine's role in reward: the case for incentive salience. | Kent C Berridge | Psychopharmacology (Berl) | 2007 | 17072591 | No |
2283 | 4286 | 1428.7 | 87.56 | 29.2 | Toll-like receptors. | Kiyoshi Takeda, Tsuneyasu Kaisho, Shizuo Akira | Annu Rev Immunol | 2003 | 12524386 | No |
2284 | 1428 | 1428.0 | 41.94 | 41.9 | Mate selection-a selection for a handicap. | A Zahavi | J Theor Biol | 1975 | 1195756 | Yes |
2285 | 1428 | 1428.0 | 36.23 | 36.2 | The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. | T Szkudelski | Physiol Res | 2001 | 11829314 | No |
2286 | 1428 | 1428.0 | 27.9 | 27.9 | A New Weighting System For Mean Surface Temperature Of The Human Body. | N L Ramanathan | J Appl Physiol | 1964 | 14173555 | Yes |
2287 | 2856 | 1428.0 | 54.93 | 27.5 | Cancer genes and the pathways they control. | Bert Vogelstein, Kenneth W Kinzler | Nat Med | 2004 | 15286780 | No |
2288 | 2856 | 1428.0 | 54.94 | 27.5 | Wnt signalling in stem cells and cancer. | Tannishtha Reya, Hans Clevers | Nature | 2005 | 15829953 | No |
2289 | 1427 | 1427.0 | 40.52 | 40.5 | Recent developments in isocyanide based multicomponent reactions in applied chemistry. | Alexander Dömling | Chem Rev | 2006 | 16402771 | No |
2290 | 1426 | 1426.0 | 25.48 | 25.5 | The DNA methyltransferases of mammals. | T H Bestor | Hum Mol Genet | 2000 | 11005794 | No |
2291 | 2851 | 1425.5 | 143.77 | 71.9 | Sensitivity Analysis in Observational Research: Introducing the E-Value. | Tyler J VanderWeele, Peng Ding | Ann Intern Med | 2017 | 28693043 | Yes |
2292 | 5701 | 1425.2 | 255.43 | 63.9 | Prevalence of childhood and adult obesity in the United States, 2011-2012. | Cynthia L Ogden, Margaret D Carroll, Brian K Kit, Katherine M Flegal | JAMA | 2014 | 24570244 | Yes |
2293 | 4274 | 1424.7 | 107.47 | 35.8 | Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. | Robert D Schreiber, Lloyd J Old, Mark J Smyth | Science | 2011 | 21436444 | No |
2294 | 1424 | 1424.0 | 34.71 | 34.7 | The cancer stem cell: premises, promises and challenges. | Hans Clevers | Nat Med | 2011 | 21386835 | No |
2295 | 1423 | 1423.0 | 33.29 | 33.3 | Functions of ceramide in coordinating cellular responses to stress. | Y A Hannun | Science | 1996 | 8943189 | No |
2296 | 5690 | 1422.5 | 227.75 | 56.9 | QUAST: quality assessment tool for genome assemblies. | Alexey Gurevich, Vladislav Saveliev, Nikolay Vyahhi, Glenn Tesler | Bioinformatics | 2013 | 23422339 | Yes |
2297 | 4267 | 1422.3 | 101.18 | 33.7 | Wnt/beta-catenin signaling: components, mechanisms, and diseases. | Bryan T MacDonald, Keiko Tamai, Xi He | Dev Cell | 2009 | 19619488 | No |
2298 | 4266 | 1422.0 | 94.35 | 31.4 | OrthoMCL: identification of ortholog groups for eukaryotic genomes. | Li Li, Christian J Stoeckert, David S Roos | Genome Res | 2003 | 12952885 | Yes |
2299 | 1422 | 1422.0 | 36.54 | 36.5 | Genetic consequences of climatic oscillations in the Quaternary. | G M Hewitt | Philos Trans R Soc Lond B Biol Sci | 2004 | 15101575 | No |
2300 | 1422 | 1422.0 | 44.6 | 44.6 | Formation of glasses from liquids and biopolymers. | C A Angell | Science | 1995 | 17770101 | Yes |
2301 | 7108 | 1421.6 | 267.55 | 53.5 | Fsl. | Mark Jenkinson, Christian F Beckmann, Timothy E J Behrens, Mark W Woolrich, Stephen M Smith | Neuroimage | 2012 | 21979382 | No |
2302 | 2843 | 1421.5 | 79.58 | 39.8 | Defining the clinical course of multiple sclerosis: results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. | F D Lublin, S C Reingold | Neurology | 1996 | 8780061 | Yes |
2303 | 1421 | 1421.0 | 40.84 | 40.8 | The aging process. | D Harman | Proc Natl Acad Sci U S A | 1981 | 6947277 | Yes |
2304 | 1421 | 1421.0 | 26.59 | 26.6 | Ubiquitin-dependent protein degradation. | M Hochstrasser | Annu Rev Genet | 1996 | 8982460 | No |
2305 | 1421 | 1421.0 | 37.65 | 37.6 | A note on robust variance estimation for cluster-correlated data. | R L Williams | Biometrics | 2000 | 10877330 | Yes |
2306 | 1421 | 1421.0 | 35.11 | 35.1 | Mitochondrial fusion and fission in cell life and death. | Benedikt Westermann | Nat Rev Mol Cell Biol | 2010 | 21102612 | No |
2307 | 2842 | 1421.0 | 86.39 | 43.2 | Molecular and cellular insights into T cell exhaustion. | E John Wherry, Makoto Kurachi | Nat Rev Immunol | 2015 | 26205583 | No |
2308 | 1420 | 1420.0 | 51.18 | 51.2 | Sodium ions, calcium ions, blood pressure regulation, and hypertension: a reassessment and a hypothesis. | M P Blaustein | Am J Physiol | 1977 | 324293 | No |
2309 | 1420 | 1420.0 | 33.57 | 33.6 | The use of nanocrystals in biological detection. | Paul Alivisatos | Nat Biotechnol | 2004 | 14704706 | Yes |
2310 | 5678 | 1419.5 | 276.4 | 69.1 | Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range. | Xiang Wan, Wenqian Wang, Jiming Liu, Tiejun Tong | BMC Med Res Methodol | 2014 | 25524443 | Yes |
2311 | 2838 | 1419.0 | 149.55 | 74.8 | Social networks, host resistance, and mortality: a nine-year follow-up study of Alameda County residents. | L F Berkman, S L Syme | Am J Epidemiol | 1979 | 425958 | Yes |
2312 | 2837 | 1418.5 | 90.14 | 45.1 | The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. | W R Gibb, A J Lees | J Neurol Neurosurg Psychiatry | 1988 | 2841426 | No |
2313 | 8507 | 1417.8 | 217.43 | 36.2 | Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. | Roy G Brower, Michael A Matthay, Alan Morris, David Schoenfeld, B Taylor Thompson, Arthur Wheeler | N Engl J Med | 2000 | 10793162 | Yes |
2314 | 2835 | 1417.5 | 62.37 | 31.2 | The pathophysiology and treatment of sepsis. | Richard S Hotchkiss, Irene E Karl | N Engl J Med | 2003 | 12519925 | No |
2315 | 1417 | 1417.0 | 0.0 | 0.0 | An approximate distribution of estimates of variance components. | F E Satterthwaite | Biometrics | 1946 | 20287815 | Yes |
2316 | 1417 | 1417.0 | 64.19 | 64.2 | PLATON SQUEEZE: a tool for the calculation of the disordered solvent contribution to the calculated structure factors. | Anthony L Spek | Acta Crystallogr C Struct Chem | 2015 | 25567569 | Yes |
2317 | 4248 | 1416.0 | 148.31 | 49.4 | Structure-antioxidant activity relationships of flavonoids and phenolic acids. | C A Rice-Evans, N J Miller, G Paganga | Free Radic Biol Med | 1996 | 8743980 | Yes |
2318 | 1416 | 1416.0 | 16.39 | 16.4 | Linked Functions And Reciprocal Effects In Hemoglobin: A Second Look. | J Wyman | Adv Protein Chem | 1964 | 14268785 | No |
2319 | 4247 | 1415.7 | 139.75 | 46.6 | Vascular endothelial cells synthesize nitric oxide from L-arginine. | R M Palmer, D S Ashton, S Moncada | Nature | 1988 | 3131684 | Yes |
2320 | 2831 | 1415.5 | 88.67 | 44.3 | Performing the exact test of Hardy-Weinberg proportion for multiple alleles. | S W Guo, E A Thompson | Biometrics | 1992 | 1637966 | Yes |
2321 | 2831 | 1415.5 | 83.43 | 41.7 | Intracellular pH. | A Roos, W F Boron | Physiol Rev | 1981 | 7012859 | No |
2322 | 2828 | 1414.0 | 52.39 | 26.2 | Oncogenic kinase signalling. | P Blume-Jensen, T Hunter | Nature | 2001 | 11357143 | No |
2323 | 1412 | 1412.0 | 34.85 | 34.9 | The carbon dioxide hydration activity of carbonic anhydrase. I. Stop-flow kinetic studies on the native human isoenzymes B and C. | R G Khalifah | J Biol Chem | 1971 | 4994926 | Yes |
2324 | 1412 | 1412.0 | 37.66 | 37.7 | Sarcopenia: origins and clinical relevance. | I H Rosenberg | J Nutr | 1997 | 9164280 | No |
2325 | 1411 | 1411.0 | 33.91 | 33.9 | Solute perturbation of protein fluorescence. The quenching of the tryptophyl fluorescence of model compounds and of lysozyme by iodide ion. | S S Lehrer | Biochemistry | 1971 | 5119250 | Yes |
2326 | 1411 | 1411.0 | 50.47 | 50.5 | Categorical Data Analysis: Away from ANOVAs (transformation or not) and towards Logit Mixed Models. | T Florian Jaeger | J Mem Lang | 2008 | 19884961 | Yes |
2327 | 1410 | 1410.0 | 35.53 | 35.5 | Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides. | Y Shai | Biochim Biophys Acta | 1999 | 10590302 | No |
2328 | 1409 | 1409.0 | 45.86 | 45.9 | Overcoming the absence of socioeconomic data in medical records: validation and application of a census-based methodology. | N Krieger | Am J Public Health | 1992 | 1566949 | Yes |
2329 | 2815 | 1407.5 | 69.91 | 35.0 | Molecular beacons: probes that fluoresce upon hybridization. | S Tyagi, F R Kramer | Nat Biotechnol | 1996 | 9630890 | Yes |
2330 | 1407 | 1407.0 | 26.17 | 26.2 | NK cell receptors. | L L Lanier | Annu Rev Immunol | 1998 | 9597134 | No |
2331 | 1407 | 1407.0 | 34.15 | 34.1 | Tobacco smoke carcinogens and lung cancer. | S S Hecht | J Natl Cancer Inst | 1999 | 10413421 | No |
2332 | 2813 | 1406.5 | 84.35 | 42.2 | Estimating wealth effects without expenditure data--or tears: an application to educational enrollments in states of India. | D Filmer, L H Pritchett | Demography | 2001 | 11227840 | Yes |
2333 | 1406 | 1406.0 | 32.69 | 32.7 | Speculations on the functions of the major heat shock and glucose-regulated proteins. | H R Pelham | Cell | 1986 | 2944601 | Yes |
2334 | 2812 | 1406.0 | 76.98 | 38.5 | Transforming growth factor beta in tissue fibrosis. | W A Border, N A Noble | N Engl J Med | 1994 | 7935686 | No |
2335 | 1406 | 1406.0 | 63.05 | 63.0 | Adjustments to Zatsiorsky-Seluyanov's segment inertia parameters. | P de Leva | J Biomech | 1996 | 8872282 | Yes |
2336 | 1406 | 1406.0 | 30.15 | 30.1 | Target-oriented and diversity-oriented organic synthesis in drug discovery. | S L Schreiber | Science | 2000 | 10720315 | No |
2337 | 2812 | 1406.0 | 0.0 | 0.0 | The effect of sodium ions on the electrical activity of giant axon of the squid. | A L Hodgkin, B Katz | J Physiol | 1949 | 18128147 | Yes |
2338 | 2811 | 1405.5 | 81.27 | 40.6 | Empirical predictions of protein conformation. | P Y Chou, G D Fasman | Annu Rev Biochem | 1978 | 354496 | No |
2339 | 2811 | 1405.5 | 55.81 | 27.9 | Prediction of complete gene structures in human genomic DNA. | C Burge, S Karlin | J Mol Biol | 1997 | 9149143 | Yes |
2340 | 2811 | 1405.5 | 69.03 | 34.5 | Myocardial reperfusion injury. | Derek M Yellon, Derek J Hausenloy | N Engl J Med | 2007 | 17855673 | No |
2341 | 2810 | 1405.0 | 93.12 | 46.6 | Social conditions as fundamental causes of disease. | B G Link, J Phelan | J Health Soc Behav | 1995 | 7560851 | No |
2342 | 1405 | 1405.0 | 44.25 | 44.2 | The amazing osteocyte. | Lynda F Bonewald | J Bone Miner Res | 2011 | 21254230 | No |
2343 | 2809 | 1404.5 | 69.26 | 34.6 | Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule. | M D Pierschbacher, E Ruoslahti | Nature | 1984 | 6325925 | Yes |
2344 | 5618 | 1404.5 | 138.92 | 34.7 | Universal sample preparation method for proteome analysis. | Jacek R Wiśniewski, Alexandre Zougman, Nagarjuna Nagaraj, Matthias Mann | Nat Methods | 2009 | 19377485 | Yes |
2345 | 2808 | 1404.0 | 70.95 | 35.5 | CLUSTAL: a package for performing multiple sequence alignment on a microcomputer. | D G Higgins, P M Sharp | Gene | 1988 | 3243435 | Yes |
2346 | 1404 | 1404.0 | 25.3 | 25.3 | Selection of successive tumour lines for metastasis. | I J Fidler | Nat New Biol | 1973 | 4512654 | Yes |
2347 | 1403 | 1403.0 | 51.19 | 51.2 | The structure of beta-lactamases. | R P Ambler | Philos Trans R Soc Lond B Biol Sci | 1980 | 6109327 | Yes |
2348 | 1403 | 1403.0 | 33.28 | 33.3 | The basic science of gene therapy. | R C Mulligan | Science | 1993 | 8493530 | No |
2349 | 1403 | 1403.0 | 40.56 | 40.6 | Depression in late life: review and commentary. | Dan G Blazer | J Gerontol A Biol Sci Med Sci | 2003 | 12634292 | No |
2350 | 1402 | 1402.0 | 12.6 | 12.6 | The Interaction of Selection and Linkage. I. General Considerations; Heterotic Models. | R C Lewontin | Genetics | 1964 | 17248194 | Yes |
2351 | 4204 | 1401.3 | 197.98 | 66.0 | Risk factors for falls among elderly persons living in the community. | M E Tinetti, M Speechley, S F Ginter | N Engl J Med | 1988 | 3205267 | Yes |
2352 | 1401 | 1401.0 | 50.5 | 50.5 | The SPQ: a scale for the assessment of schizotypal personality based on DSM-III-R criteria. | A Raine | Schizophr Bull | 1991 | 1805349 | Yes |
2353 | 2802 | 1401.0 | 42.08 | 21.0 | Prediction of protein conformation. | P Y Chou, G D Fasman | Biochemistry | 1974 | 4358940 | Yes |
2354 | 1401 | 1401.0 | 29.62 | 29.6 | A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. | Dale R Nyholt | Am J Hum Genet | 2004 | 14997420 | Yes |
2355 | 2802 | 1401.0 | 62.32 | 31.2 | Raster3D Version 2.0. A program for photorealistic molecular graphics. | E A Merritt, M E Murphy | Acta Crystallogr D Biol Crystallogr | 1994 | 15299354 | Yes |
2356 | 1401 | 1401.0 | 54.0 | 54.0 | What is self-rated health and why does it predict mortality? Towards a unified conceptual model. | Marja Jylhä | Soc Sci Med | 2009 | 19520474 | Yes |
2357 | 1401 | 1401.0 | 32.38 | 32.4 | Recent advances in neuroblastoma. | John M Maris | N Engl J Med | 2010 | 20558371 | No |
2358 | 2800 | 1400.0 | 0.0 | 0.0 | Virus interference. I. The interferon. | A Isaacs, J Lindenmann | Proc R Soc Lond B Biol Sci | 1957 | 13465720 | Yes |
2359 | 2800 | 1400.0 | 89.79 | 44.9 | Origins and evolution of antibiotic resistance. | Julian Davies, Dorothy Davies | Microbiol Mol Biol Rev | 2010 | 20805405 | No |
2360 | 1399 | 1399.0 | 31.9 | 31.9 | Protein kinase C: structure, function, and regulation. | A C Newton | J Biol Chem | 1995 | 7499357 | No |
2361 | 1399 | 1399.0 | 30.63 | 30.6 | The ATP synthase--a splendid molecular machine. | P D Boyer | Annu Rev Biochem | 1997 | 9242922 | No |
2362 | 2796 | 1398.0 | 82.49 | 41.2 | Glycine potentiates the NMDA response in cultured mouse brain neurons. | J W Johnson, P Ascher | Nature | 1987 | 2433595 | Yes |
2363 | 1398 | 1398.0 | 17.42 | 17.4 | Hippocampal electrical activity and voluntary movement in the rat. | C H Vanderwolf | Electroencephalogr Clin Neurophysiol | 1969 | 4183562 | Yes |
2364 | 1398 | 1398.0 | 33.26 | 33.3 | Drug-induced prolongation of the QT interval. | Dan M Roden | N Engl J Med | 2004 | 14999113 | No |
2365 | 2795 | 1397.5 | 67.55 | 33.8 | Powering the planet: chemical challenges in solar energy utilization. | Nathan S Lewis, Daniel G Nocera | Proc Natl Acad Sci U S A | 2006 | 17043226 | Yes |
2366 | 4192 | 1397.3 | 84.23 | 28.1 | The versatility and universality of calcium signalling. | M J Berridge, P Lipp, M D Bootman | Nat Rev Mol Cell Biol | 2000 | 11413485 | No |
2367 | 1397 | 1397.0 | 28.88 | 28.9 | Origin of concatemeric T7 DNA. | J D Watson | Nat New Biol | 1972 | 4507727 | Yes |
2368 | 2793 | 1396.5 | 70.11 | 35.1 | Enzyme-linked immunosorbent assay (ELISA). Quantitative assay of immunoglobulin G. | E Engvall, P Perlmann | Immunochemistry | 1971 | 5135623 | Yes |
2369 | 2793 | 1396.5 | 61.32 | 30.7 | An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. | A A Beg, D Baltimore | Science | 1996 | 8864118 | Yes |
2370 | 2793 | 1396.5 | 65.73 | 32.9 | Inflammation, stress, and diabetes. | Kathryn E Wellen, Gökhan S Hotamisligil | J Clin Invest | 2005 | 15864338 | No |
2371 | 1396 | 1396.0 | 30.05 | 30.1 | Physiological concentrations of purines and pyrimidines. | T W Traut | Mol Cell Biochem | 1994 | 7877593 | No |
2372 | 1396 | 1396.0 | 26.96 | 27.0 | Natively unfolded proteins: a point where biology waits for physics. | Vladimir N Uversky | Protein Sci | 2002 | 11910019 | No |
2373 | 1396 | 1396.0 | 29.47 | 29.5 | Cancer of the ovary. | Stephen A Cannistra | N Engl J Med | 2004 | 15590954 | No |
2374 | 2792 | 1396.0 | 74.51 | 37.3 | Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. | Robert E W Hancock, Hans-Georg Sahl | Nat Biotechnol | 2006 | 17160061 | No |
2375 | 1396 | 1396.0 | 44.28 | 44.3 | Synopsis of some recent tactical application of bioisosteres in drug design. | Nicholas A Meanwell | J Med Chem | 2011 | 21413808 | Yes |
2376 | 4186 | 1395.3 | 87.64 | 29.2 | Multidrug resistance in cancer: role of ATP-dependent transporters. | Michael M Gottesman, Tito Fojo, Susan E Bates | Nat Rev Cancer | 2002 | 11902585 | No |
2377 | 6976 | 1395.2 | 257.59 | 51.5 | Evidence based medicine: what it is and what it isn't. | D L Sackett, W M Rosenberg, J A Gray, R B Haynes, W S Richardson | BMJ | 1996 | 8555924 | No |
2378 | 4185 | 1395.0 | 111.51 | 37.2 | TCS: a computer program to estimate gene genealogies. | M Clement, D Posada, K A Crandall | Mol Ecol | 2000 | 11050560 | Yes |
2379 | 4185 | 1395.0 | 135.22 | 45.1 | Global estimates of the prevalence of diabetes for 2010 and 2030. | J E Shaw, R A Sicree, P Z Zimmet | Diabetes Res Clin Pract | 2010 | 19896746 | Yes |
2380 | 2790 | 1395.0 | 107.93 | 54.0 | Natural products as sources of new drugs over the 30 years from 1981 to 2010. | David J Newman, Gordon M Cragg | J Nat Prod | 2012 | 22316239 | No |
2381 | 2789 | 1394.5 | 81.71 | 40.9 | Microdetermination of long-chain fatty acids in plasma and tissues. | V P Dole, H Meinertz | J Biol Chem | 1960 | 13817286 | Yes |
2382 | 1393 | 1393.0 | 48.63 | 48.6 | The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles. | Eleonore Fröhlich | Int J Nanomedicine | 2012 | 23144561 | No |
2383 | 2785 | 1392.5 | 112.25 | 56.1 | The Warburg Effect: How Does it Benefit Cancer Cells? | Maria V Liberti, Jason W Locasale | Trends Biochem Sci | 2016 | 26778478 | No |
2384 | 1392 | 1392.0 | 49.81 | 49.8 | Quantitative methods in the review of epidemiologic literature. | S Greenland | Epidemiol Rev | 1987 | 3678409 | Yes |
2385 | 4176 | 1392.0 | 98.91 | 33.0 | Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. | Daniel Falush, Matthew Stephens, Jonathan K Pritchard | Genetics | 2003 | 12930761 | Yes |
2386 | 1391 | 1391.0 | 64.19 | 64.2 | Biological roles of glycans. | Ajit Varki | Glycobiology | 2017 | 27558841 | No |
2387 | 2781 | 1390.5 | 80.36 | 40.2 | Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. | C J Murray, A D Lopez | Lancet | 1997 | 9164317 | Yes |
2388 | 6951 | 1390.2 | 365.91 | 73.2 | ModelFinder: fast model selection for accurate phylogenetic estimates. | Subha Kalyaanamoorthy, Bui Quang Minh, Thomas K F Wong, Arndt von Haeseler, Lars S Jermiin | Nat Methods | 2017 | 28481363 | Yes |
2389 | 9731 | 1390.1 | 242.15 | 34.6 | Integrative genomics viewer. | James T Robinson, Helga Thorvaldsdóttir, Wendy Winckler, Mitchell Guttman, Eric S Lander, Gad Getz, Jill P Mesirov | Nat Biotechnol | 2011 | 21221095 | Yes |
2390 | 1390 | 1390.0 | 52.81 | 52.8 | Presidential address, 1980. Surprise!...Surprise? | E Donchin | Psychophysiology | 1981 | 7280146 | Yes |
2391 | 4170 | 1390.0 | 101.89 | 34.0 | Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm. | Y Zhang, M Brady, S Smith | IEEE Trans Med Imaging | 2001 | 11293691 | Yes |
2392 | 1389 | 1389.0 | 24.25 | 24.2 | The snail superfamily of zinc-finger transcription factors. | M Angela Nieto | Nat Rev Mol Cell Biol | 2002 | 11994736 | No |
2393 | 2776 | 1388.0 | 100.88 | 50.4 | Biology of disease: free radicals and tissue injury. | B A Freeman, J D Crapo | Lab Invest | 1982 | 6290784 | No |
2394 | 2776 | 1388.0 | 111.01 | 55.5 | A typology of reviews: an analysis of 14 review types and associated methodologies. | Maria J Grant, Andrew Booth | Health Info Libr J | 2009 | 19490148 | No |
2395 | 2775 | 1387.5 | 74.5 | 37.2 | Antibiotic resistance of bacteria in biofilms. | P S Stewart, J W Costerton | Lancet | 2001 | 11463434 | No |
2396 | 2774 | 1387.0 | 63.89 | 31.9 | Emerging roles of caspase-3 in apoptosis. | A G Porter, R U Jänicke | Cell Death Differ | 1999 | 10200555 | No |
2397 | 2772 | 1386.0 | 95.55 | 47.8 | Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans. | D H Figurski, D R Helinski | Proc Natl Acad Sci U S A | 1979 | 377280 | Yes |
2398 | 1386 | 1386.0 | 51.41 | 51.4 | Microtiter dish biofilm formation assay. | George A O'Toole | J Vis Exp | 2011 | 21307833 | Yes |
2399 | 6928 | 1385.6 | 200.67 | 40.1 | Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. | Ronald C Kessler, Wai Tat Chiu, Olga Demler, Kathleen R Merikangas, Ellen E Walters | Arch Gen Psychiatry | 2005 | 15939839 | Yes |
2400 | 2770 | 1385.0 | 71.34 | 35.7 | A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments. | J Messing, J Vieira | Gene | 1982 | 6295880 | Yes |
2401 | 1385 | 1385.0 | 30.84 | 30.8 | Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles. | M Kozak | Microbiol Rev | 1983 | 6343825 | No |
2402 | 1385 | 1385.0 | 43.0 | 43.0 | The projections of the ventral tegmental area and adjacent regions: a combined fluorescent retrograde tracer and immunofluorescence study in the rat. | L W Swanson | Brain Res Bull | 1982 | 6816390 | Yes |
2403 | 1385 | 1385.0 | 30.18 | 30.2 | Measuring information transfer | T Schreiber | Phys Rev Lett | 2000 | 10991308 | Yes |
2404 | 2769 | 1384.5 | 58.34 | 29.2 | LTP and LTD: an embarrassment of riches. | Robert C Malenka, Mark F Bear | Neuron | 2004 | 15450156 | No |
2405 | 5537 | 1384.2 | 207.81 | 52.0 | Bayesian phylogenetics with BEAUti and the BEAST 1.7. | Alexei J Drummond, Marc A Suchard, Dong Xie, Andrew Rambaut | Mol Biol Evol | 2012 | 22367748 | Yes |
2406 | 6919 | 1383.8 | 167.98 | 33.6 | Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. | Sarah Lewington, Robert Clarke, Nawab Qizilbash, Richard Peto, Rory Collins | Lancet | 2002 | 12493255 | Yes |
2407 | 2767 | 1383.5 | 65.8 | 32.9 | Regulation mechanisms and signaling pathways of autophagy. | Congcong He, Daniel J Klionsky | Annu Rev Genet | 2009 | 19653858 | No |
2408 | 2766 | 1383.0 | 35.75 | 17.9 | Evidence For The Existence Of Monoamine-Containing Neurons In The Central Nervous System. I. Demonstration Of Monoamines In The Cell Bodies Of Brain Stem Neurons. | A Dahlstroem, K Fuxe | Acta Physiol Scand Suppl | 1964 | 14229500 | Yes |
2409 | 1383 | 1383.0 | 57.85 | 57.9 | The Laboratory Rat: Relating Its Age With Human's. | Pallav Sengupta | Int J Prev Med | 2013 | 23930179 | Yes |
2410 | 1383 | 1383.0 | 120.63 | 120.6 | A Review of Coronavirus Disease-2019 (COVID-19). | Tanu Singhal | Indian J Pediatr | 2020 | 32166607 | No |
2411 | 1382 | 1382.0 | 27.04 | 27.0 | The origin of the genetic code. | F H Crick | J Mol Biol | 1968 | 4887876 | Yes |
2412 | 1382 | 1382.0 | 32.34 | 32.3 | Regulation of differentiation of vascular smooth muscle cells. | G K Owens | Physiol Rev | 1995 | 7624392 | No |
2413 | 1382 | 1382.0 | 31.09 | 31.1 | Molecular basis of long-term plasticity underlying addiction. | E J Nestler | Nat Rev Neurosci | 2001 | 11252991 | No |
2414 | 1382 | 1382.0 | 0.0 | 0.0 | The critical incident technique. | J C Flanagan | Psychol Bull | 1954 | 13177800 | Yes |
2415 | 2764 | 1382.0 | 61.35 | 30.7 | Immunoassay of endogenous plasma insulin in man. | R S Yalow, S A Berson | J Clin Invest | 1960 | 13846364 | Yes |
2416 | 1382 | 1382.0 | 0.0 | 0.0 | Intracellular distribution of enzymes; the oxidation of octanoic acid by rat liver fractions. | W C Schneider | J Biol Chem | 1948 | 18886166 | Yes |
2417 | 2762 | 1381.0 | 70.18 | 35.1 | A method of trace iodination of proteins for immunologic studies. | P J McConahey, F J Dixon | Int Arch Allergy Appl Immunol | 1966 | 4160044 | Yes |
2418 | 1381 | 1381.0 | 52.21 | 52.2 | Translating social ecological theory into guidelines for community health promotion. | D Stokols | Am J Health Promot | 1996 | 10159709 | No |
2419 | 2761 | 1380.5 | 94.15 | 47.1 | A new scale of social desirability independent of psychopathology. | D P Crowne, D Marlowe | J Consult Psychol | 1960 | 13813058 | Yes |
2420 | 1380 | 1380.0 | 35.2 | 35.2 | The human orbitofrontal cortex: linking reward to hedonic experience. | Morten L Kringelbach | Nat Rev Neurosci | 2005 | 16136173 | No |
2421 | 2760 | 1380.0 | 84.73 | 42.4 | Tumor-associated macrophages: from mechanisms to therapy. | Roy Noy, Jeffrey W Pollard | Immunity | 2014 | 25035953 | No |
2422 | 4139 | 1379.7 | 142.58 | 47.5 | Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. | Marina Colombo, Graça Raposo, Clotilde Théry | Annu Rev Cell Dev Biol | 2014 | 25288114 | No |
2423 | 1379 | 1379.0 | 31.67 | 31.7 | Huntington's disease. | Francis O Walker | Lancet | 2007 | 17240289 | No |
2424 | 1379 | 1379.0 | 57.04 | 57.0 | 1,500 scientists lift the lid on reproducibility. | Monya Baker | Nature | 2016 | 27225100 | No |
2425 | 2755 | 1377.5 | 76.99 | 38.5 | Epidemiology of invasive candidiasis: a persistent public health problem. | M A Pfaller, D J Diekema | Clin Microbiol Rev | 2007 | 17223626 | No |
2426 | 1377 | 1377.0 | 36.66 | 36.7 | Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications. | P Lips | Endocr Rev | 2001 | 11493580 | No |
2427 | 4131 | 1377.0 | 91.51 | 30.5 | Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides. | Christian W Tornøe, Caspar Christensen, Morten Meldal | J Org Chem | 2002 | 11975567 | Yes |
2428 | 1377 | 1377.0 | 56.61 | 56.6 | Rhythms for Cognition: Communication through Coherence. | Pascal Fries | Neuron | 2015 | 26447583 | No |
2429 | 1377 | 1377.0 | 71.47 | 71.5 | ROS Are Good. | Ron Mittler | Trends Plant Sci | 2017 | 27666517 | No |
2430 | 1375 | 1375.0 | 59.67 | 59.7 | Refinement of the coomassie blue method of protein quantitation. A simple and linear spectrophotometric assay for less than or equal to 0.5 to 50 microgram of protein. | T Spector | Anal Biochem | 1978 | 655375 | Yes |
2431 | 1375 | 1375.0 | 27.94 | 27.9 | Stability and flexibility of epigenetic gene regulation in mammalian development. | Wolf Reik | Nature | 2007 | 17522676 | No |
2432 | 9624 | 1374.9 | 389.0 | 55.6 | Development and validation of a geriatric depression screening scale: a preliminary report. | J A Yesavage, T L Brink, T L Rose, O Lum, V Huang, M Adey, V O Leirer | J Psychiatr Res | 1982 | 7183759 | Yes |
2433 | 2749 | 1374.5 | 70.48 | 35.2 | Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins. | D Marion, K Wüthrich | Biochem Biophys Res Commun | 1983 | 6307308 | Yes |
2434 | 1374 | 1374.0 | 23.89 | 23.9 | Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction. | J R David | Proc Natl Acad Sci U S A | 1966 | 5229858 | Yes |
2435 | 1374 | 1374.0 | 39.18 | 39.2 | Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation. | P Willner | Psychopharmacology (Berl) | 1997 | 9452163 | No |
2436 | 1373 | 1373.0 | 52.81 | 52.8 | Minority stress and mental health in gay men. | I H Meyer | J Health Soc Behav | 1995 | 7738327 | Yes |
2437 | 1373 | 1373.0 | 36.43 | 36.4 | Atopic dermatitis. | Thomas Bieber | N Engl J Med | 2008 | 18385500 | Yes |
2438 | 2745 | 1372.5 | 77.29 | 38.6 | Mortality by cause for eight regions of the world: Global Burden of Disease Study. | C J Murray, A D Lopez | Lancet | 1997 | 9142060 | Yes |
2439 | 1372 | 1372.0 | 22.33 | 22.3 | Cancer. Addiction to oncogenes--the Achilles heal of cancer. | I Bernard Weinstein | Science | 2002 | 12098689 | No |
2440 | 1372 | 1372.0 | 28.59 | 28.6 | The enzymes, regulation, and genetics of bile acid synthesis. | David W Russell | Annu Rev Biochem | 2003 | 12543708 | No |
2441 | 2743 | 1371.5 | 92.25 | 46.1 | Functional interactions between the gut microbiota and host metabolism. | Valentina Tremaroli, Fredrik Bäckhed | Nature | 2012 | 22972297 | No |
2442 | 1371 | 1371.0 | 60.02 | 60.0 | Displaced proximal humeral fractures. I. Classification and evaluation. | C S Neer | J Bone Joint Surg Am | 1970 | 5455339 | Yes |
2443 | 5484 | 1371.0 | 236.01 | 59.0 | Progressive statistics for studies in sports medicine and exercise science. | William G Hopkins, Stephen W Marshall, Alan M Batterham, Juri Hanin | Med Sci Sports Exerc | 2009 | 19092709 | No |
2444 | 2741 | 1370.5 | 54.95 | 27.5 | Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids. | A J Berk, P A Sharp | Cell | 1977 | 922889 | Yes |
2445 | 2741 | 1370.5 | 85.67 | 42.8 | A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. | R L Juliano, V Ling | Biochim Biophys Acta | 1976 | 990323 | Yes |
2446 | 8223 | 1370.5 | 206.34 | 34.4 | A default mode of brain function. | M E Raichle, A M MacLeod, A Z Snyder, W J Powers, D A Gusnard, G L Shulman | Proc Natl Acad Sci U S A | 2001 | 11209064 | Yes |
2447 | 1370 | 1370.0 | 28.37 | 28.4 | Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators. | R I Morimoto | Genes Dev | 1998 | 9869631 | No |
2448 | 1370 | 1370.0 | 25.72 | 25.7 | Epithelial-mesenchymal transitions in development and pathologies. | Jean Paul Thiery | Curr Opin Cell Biol | 2003 | 14644200 | No |
2449 | 2739 | 1369.5 | 80.23 | 40.1 | A cognitive model of posttraumatic stress disorder. | A Ehlers, D M Clark | Behav Res Ther | 2000 | 10761279 | No |
2450 | 2739 | 1369.5 | 68.14 | 34.1 | The neural basis of human error processing: reinforcement learning, dopamine, and the error-related negativity. | Clay B Holroyd, Michael G H Coles | Psychol Rev | 2002 | 12374324 | Yes |
2451 | 2739 | 1369.5 | 86.04 | 43.0 | DPARSF: A MATLAB Toolbox for "Pipeline" Data Analysis of Resting-State fMRI. | Yan Chao-Gan, Zang Yu-Feng | Front Syst Neurosci | 2010 | 20577591 | Yes |
2452 | 2739 | 1369.5 | 76.72 | 38.4 | The OPLS [optimized potentials for liquid simulations] potential functions for proteins, energy minimizations for crystals of cyclic peptides and crambin. | W L Jorgensen, J Tirado-Rives | J Am Chem Soc | 1988 | 27557051 | Yes |
2453 | 1369 | 1369.0 | 42.65 | 42.6 | Glutathione metabolism and its selective modification. | A Meister | J Biol Chem | 1988 | 3053703 | No |
2454 | 1369 | 1369.0 | 24.74 | 24.7 | c-Myc target genes involved in cell growth, apoptosis, and metabolism. | C V Dang | Mol Cell Biol | 1999 | 9858526 | No |
2455 | 1369 | 1369.0 | 42.03 | 42.0 | Chronic disease management: what will it take to improve care for chronic illness? | E H Wagner | Eff Clin Pract | 1998 | 10345255 | No |
2456 | 4106 | 1368.7 | 116.99 | 39.0 | A rapid bootstrap algorithm for the RAxML Web servers. | Alexandros Stamatakis, Paul Hoover, Jacques Rougemont | Syst Biol | 2008 | 18853362 | Yes |
2457 | 2737 | 1368.5 | 73.94 | 37.0 | miRBase: integrating microRNA annotation and deep-sequencing data. | Ana Kozomara, Sam Griffiths-Jones | Nucleic Acids Res | 2011 | 21037258 | Yes |
2458 | 2734 | 1367.0 | 61.84 | 30.9 | Disruption of epithelial cell-matrix interactions induces apoptosis. | S M Frisch, H Francis | J Cell Biol | 1994 | 8106557 | Yes |
2459 | 1367 | 1367.0 | 29.96 | 30.0 | Diarylethenes for Memories and Switches. | Masahiro Irie | Chem Rev | 2000 | 11777416 | Yes |
2460 | 1367 | 1367.0 | 41.62 | 41.6 | Nanobodies: natural single-domain antibodies. | Serge Muyldermans | Annu Rev Biochem | 2013 | 23495938 | No |
2461 | 2734 | 1367.0 | 80.83 | 40.4 | The Measurement Of Selection On Correlated Characters. | Russell Lande, Stevan J Arnold | Evolution | 1983 | 28556011 | Yes |
2462 | 2733 | 1366.5 | 59.36 | 29.7 | NMR View: A computer program for the visualization and analysis of NMR data. | B A Johnson, R A Blevins | J Biomol NMR | 1994 | 22911360 | Yes |
2463 | 4099 | 1366.3 | 119.44 | 39.8 | Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins. | J Garnier, D J Osguthorpe, B Robson | J Mol Biol | 1978 | 642007 | Yes |
2464 | 8198 | 1366.3 | 271.22 | 45.2 | The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. | Erik von Elm, Douglas G Altman, Matthias Egger, Stuart J Pocock, Peter C Gøtzsche, Jan P Vandenbroucke | J Clin Epidemiol | 2008 | 18313558 | Yes |
2465 | 1366 | 1366.0 | 28.74 | 28.7 | HIF-1: mediator of physiological and pathophysiological responses to hypoxia. | G L Semenza | J Appl Physiol (1985) | 2000 | 10749844 | No |
2466 | 1366 | 1366.0 | 0.0 | 0.0 | An improved procedure for starch-gel electrophoresis: further variations in the serum proteins of normal individuals. | O Smithies | Biochem J | 1959 | 13638269 | Yes |
2467 | 2732 | 1366.0 | 66.16 | 33.1 | The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. | Daniel J Drucker, Michael A Nauck | Lancet | 2006 | 17098089 | No |
2468 | 1366 | 1366.0 | 44.83 | 44.8 | Phenylpropanoid biosynthesis. | Thomas Vogt | Mol Plant | 2010 | 20035037 | No |
2469 | 1364 | 1364.0 | 47.9 | 47.9 | Multiple calcium channels and neuronal function. | R J Miller | Science | 1987 | 2432656 | No |
2470 | 1364 | 1364.0 | 38.59 | 38.6 | Subcutaneous and visceral adipose tissue: structural and functional differences. | M Mohsen Ibrahim | Obes Rev | 2010 | 19656312 | No |
2471 | 1364 | 1364.0 | 104.76 | 104.8 | Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults. | Jonas F Ludvigsson | Acta Paediatr | 2020 | 32202343 | Yes |
2472 | 2727 | 1363.5 | 96.01 | 48.0 | A sensitive silver stain for detecting lipopolysaccharides in polyacrylamide gels. | C M Tsai, C E Frasch | Anal Biochem | 1982 | 6176137 | Yes |
2473 | 2727 | 1363.5 | 0.0 | 0.0 | The respiratory chain and oxidative phosphorylation. | B Chance, G R Williams | Adv Enzymol Relat Subj Biochem | 1956 | 13313307 | Yes |
2474 | 2726 | 1363.0 | 66.15 | 33.1 | Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. | M P Lutolf, J A Hubbell | Nat Biotechnol | 2005 | 15637621 | No |
2475 | 1363 | 1363.0 | 42.07 | 42.1 | Evaluating the quality of medical care. 1966. | Avedis Donabedian | Milbank Q | 2005 | 16279964 | No |
2476 | 1363 | 1363.0 | 45.66 | 45.7 | AmpC beta-lactamases. | George A Jacoby | Clin Microbiol Rev | 2009 | 19136439 | No |
2477 | 2725 | 1362.5 | 56.08 | 28.0 | Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter. | P J Southern, P Berg | J Mol Appl Genet | 1982 | 6286831 | Yes |
2478 | 2725 | 1362.5 | 72.44 | 36.2 | Tumor metastasis: molecular insights and evolving paradigms. | Scott Valastyan, Robert A Weinberg | Cell | 2011 | 22000009 | No |
2479 | 2725 | 1362.5 | 107.02 | 53.5 | Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities. | Roel Nusse, Hans Clevers | Cell | 2017 | 28575679 | No |
2480 | 2724 | 1362.0 | 53.78 | 26.9 | A protein sequenator. | P Edman, G Begg | Eur J Biochem | 1967 | 6059350 | Yes |
2481 | 1362 | 1362.0 | 24.09 | 24.1 | Chromatin modification and epigenetic reprogramming in mammalian development. | En Li | Nat Rev Genet | 2002 | 12209141 | No |
2482 | 1362 | 1362.0 | 29.68 | 29.7 | Transcriptional control of adipocyte formation. | Stephen R Farmer | Cell Metab | 2006 | 17011499 | No |
2483 | 1362 | 1362.0 | 28.15 | 28.1 | Human natural killer cells. | Michael A Caligiuri | Blood | 2008 | 18650461 | No |
2484 | 1362 | 1362.0 | 31.79 | 31.8 | Non-Smad pathways in TGF-beta signaling. | Ying E Zhang | Cell Res | 2009 | 19114990 | No |
2485 | 1361 | 1361.0 | 29.14 | 29.1 | Codon usage and tRNA content in unicellular and multicellular organisms. | T Ikemura | Mol Biol Evol | 1985 | 3916708 | No |
2486 | 2722 | 1361.0 | 64.92 | 32.5 | Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. | Subhra K Biswas, Alberto Mantovani | Nat Immunol | 2010 | 20856220 | No |
2487 | 1360 | 1360.0 | 42.97 | 43.0 | Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: a hypothesis for the etiology of schizophrenia. | A A Grace | Neuroscience | 1991 | 1676137 | No |
2488 | 1360 | 1360.0 | 46.26 | 46.3 | Interleukin-1. | C A Dinarello | Rev Infect Dis | 1984 | 6369481 | No |
2489 | 1360 | 1360.0 | 31.16 | 31.2 | Two's company, three's a crowd: can H2S be the third endogenous gaseous transmitter? | Rui Wang | FASEB J | 2002 | 12409322 | Yes |
2490 | 2719 | 1359.5 | 72.64 | 36.3 | Chlorophyll fluorescence--a practical guide. | K Maxwell, G N Johnson | J Exp Bot | 2000 | 10938857 | No |
2491 | 1359 | 1359.0 | 32.73 | 32.7 | Membrane protein structure prediction. Hydrophobicity analysis and the positive-inside rule. | G von Heijne | J Mol Biol | 1992 | 1593632 | Yes |
2492 | 1359 | 1359.0 | 37.38 | 37.4 | The pollution of the marine environment by plastic debris: a review. | José G B Derraik | Mar Pollut Bull | 2002 | 12405208 | No |
2493 | 2717 | 1358.5 | 125.01 | 62.5 | Glutathione peroxidase activity in selenium-deficient rat liver. | R A Lawrence, R F Burk | Biochem Biophys Res Commun | 1976 | 971321 | Yes |
2494 | 1358 | 1358.0 | 0.0 | 0.0 | Effects of varying the vehicle for OsO4 in tissue fixation. | J B Caulfield | J Biophys Biochem Cytol | 1957 | 13475399 | Yes |
2495 | 1358 | 1358.0 | 40.23 | 40.2 | Cross-dehydrogenative coupling (CDC): exploring C-C bond formations beyond functional group transformations. | Chao-Jun Li | Acc Chem Res | 2009 | 19220064 | Yes |
2496 | 1357 | 1357.0 | 37.65 | 37.6 | Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles. | Felix Kratz | J Control Release | 2008 | 18582981 | No |
2497 | 1355 | 1355.0 | 43.47 | 43.5 | History of the Rochester Epidemiology Project. | L J Melton | Mayo Clin Proc | 1996 | 8594285 | No |
2498 | 1355 | 1355.0 | 27.44 | 27.4 | The many faces of macrophage activation. | David M Mosser | J Leukoc Biol | 2003 | 12554797 | No |
2499 | 1355 | 1355.0 | 34.25 | 34.2 | Microbial influences in inflammatory bowel diseases. | R Balfour Sartor | Gastroenterology | 2008 | 18242222 | No |
2500 | 6769 | 1353.8 | 183.33 | 36.7 | Transection of the oesophagus for bleeding oesophageal varices. | R N Pugh, I M Murray-Lyon, J L Dawson, M C Pietroni, R Williams | Br J Surg | 1973 | 4541913 | Yes |
2501 | 1353 | 1353.0 | 40.12 | 40.1 | Classification of chronic viral hepatitis: a need for reassessment. | P J Scheuer | J Hepatol | 1991 | 1808228 | No |
2502 | 2706 | 1353.0 | 93.89 | 46.9 | Total energy intake: implications for epidemiologic analyses. | W Willett, M J Stampfer | Am J Epidemiol | 1986 | 3521261 | No |
2503 | 1353 | 1353.0 | 64.79 | 64.8 | Molecular pathology of schizophrenia: more than one disease process? | T J Crow | Br Med J | 1980 | 6101544 | No |
2504 | 1352 | 1352.0 | 48.29 | 48.3 | Letter: Grading of angina pectoris. | L Campeau | Circulation | 1976 | 947585 | Yes |
2505 | 1352 | 1352.0 | 25.89 | 25.9 | Mechanisms of caspase activation and inhibition during apoptosis. | Yigong Shi | Mol Cell | 2002 | 11931755 | No |
2506 | 1352 | 1352.0 | 11.74 | 11.7 | Immunological function of the thymus. | J F Miller | Lancet | 1961 | 14474038 | Yes |
2507 | 4056 | 1352.0 | 88.78 | 29.6 | Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. | Axel Nimmerjahn, Frank Kirchhoff, Fritjof Helmchen | Science | 2005 | 15831717 | Yes |
2508 | 1352 | 1352.0 | 30.44 | 30.4 | Tumour necrosis factor and cancer. | Frances Balkwill | Nat Rev Cancer | 2009 | 19343034 | No |
2509 | 2703 | 1351.5 | 55.01 | 27.5 | Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. | J M Kyriakis, J Avruch | Physiol Rev | 2001 | 11274345 | No |
2510 | 1351 | 1351.0 | 41.19 | 41.2 | Neurotransmitters and neuromodulators in the basal ganglia. | A M Graybiel | Trends Neurosci | 1990 | 1695398 | No |
2511 | 1351 | 1351.0 | 34.65 | 34.6 | The biologic clock: the mitochondria? | D Harman | J Am Geriatr Soc | 1972 | 5016631 | Yes |
2512 | 1351 | 1351.0 | 58.28 | 58.3 | Blood gas calculator. | J W Severinghaus | J Appl Physiol | 1966 | 5912737 | Yes |
2513 | 2700 | 1350.0 | 62.16 | 31.1 | NF-kappa B: ten years after. | P A Baeuerle, D Baltimore | Cell | 1996 | 8858144 | No |
2514 | 4048 | 1349.3 | 49.84 | 16.6 | Cytochemistry and electron microscopy. The preservation of cellular ultrastructure and enzymatic activity by aldehyde fixation. | D D Sabatini, K Bensch, R J Barrnett | J Cell Biol | 1963 | 13975866 | Yes |
2515 | 1349 | 1349.0 | 41.53 | 41.5 | Renin-angiotensin system: biochemistry and mechanisms of action. | M J Peach | Physiol Rev | 1977 | 191856 | No |
2516 | 1349 | 1349.0 | 26.88 | 26.9 | Dimerization of cell surface receptors in signal transduction. | C H Heldin | Cell | 1995 | 7834741 | No |
2517 | 1349 | 1349.0 | 33.73 | 33.7 | A molecular view of microbial diversity and the biosphere. | N R Pace | Science | 1997 | 9115194 | No |
2518 | 1349 | 1349.0 | 73.51 | 73.5 | DLS and zeta potential - What they are and what they are not? | Sourav Bhattacharjee | J Control Release | 2016 | 27297779 | No |
2519 | 1348 | 1348.0 | 43.92 | 43.9 | Optimal foraging, the marginal value theorem. | E L Charnov | Theor Popul Biol | 1976 | 1273796 | Yes |
2520 | 1348 | 1348.0 | 64.48 | 64.5 | The clinical application of the biopsychosocial model. | G L Engel | Am J Psychiatry | 1980 | 7369396 | Yes |
2521 | 1348 | 1348.0 | 25.95 | 25.9 | Chromosomal translocations in human cancer. | T H Rabbitts | Nature | 1994 | 7969446 | No |
2522 | 1348 | 1348.0 | 27.4 | 27.4 | Solving structures of protein complexes by molecular replacement with Phaser. | Airlie J McCoy | Acta Crystallogr D Biol Crystallogr | 2007 | 17164524 | Yes |
2523 | 1347 | 1347.0 | 25.77 | 25.8 | microRNAs: tiny regulators with great potential. | V Ambros | Cell | 2001 | 11779458 | No |
2524 | 5384 | 1346.0 | 126.25 | 31.6 | The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling. | Konstantin Arnold, Lorenza Bordoli, Jürgen Kopp, Torsten Schwede | Bioinformatics | 2006 | 16301204 | Yes |
2525 | 1346 | 1346.0 | 41.4 | 41.4 | Electrocatalyst approaches and challenges for automotive fuel cells. | Mark K Debe | Nature | 2012 | 22678278 | Yes |
2526 | 1346 | 1346.0 | 100.19 | 100.2 | The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) - China, 2020. | The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team | China CDC Wkly | 2020 | 34594836 | Yes |
2527 | 5383 | 1345.8 | 123.93 | 31.0 | Quantitative monitoring of gene expression patterns with a complementary DNA microarray. | M Schena, D Shalon, R W Davis, P O Brown | Science | 1995 | 7569999 | Yes |
2528 | 1345 | 1345.0 | 35.48 | 35.5 | Seminars in medicine of the Beth Israel Hospital, Boston. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies. | S L Friedman | N Engl J Med | 1993 | 8502273 | No |
2529 | 1345 | 1345.0 | 39.88 | 39.9 | Circuitry and functional aspects of the insular lobe in primates including humans. | J R Augustine | Brain Res Brain Res Rev | 1996 | 8957561 | No |
2530 | 1344 | 1344.0 | 20.44 | 20.4 | A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon. | A M Olovnikov | J Theor Biol | 1973 | 4754905 | Yes |
2531 | 1344 | 1344.0 | 0.0 | 0.0 | A simple ultraviolet spectrophotometric method for the determination of protein. | W J Waddell | J Lab Clin Med | 1956 | 13346201 | Yes |
2532 | 2688 | 1344.0 | 60.04 | 30.0 | Cell cycle, CDKs and cancer: a changing paradigm. | Marcos Malumbres, Mariano Barbacid | Nat Rev Cancer | 2009 | 19238148 | No |
2533 | 5375 | 1343.8 | 192.58 | 48.1 | Near-optimal probabilistic RNA-seq quantification. | Nicolas L Bray, Harold Pimentel, Páll Melsted, Lior Pachter | Nat Biotechnol | 2016 | 27043002 | Yes |
2534 | 2687 | 1343.5 | 61.25 | 30.6 | The RXR heterodimers and orphan receptors. | D J Mangelsdorf, R M Evans | Cell | 1995 | 8521508 | No |
2535 | 2685 | 1342.5 | 67.77 | 33.9 | Therapeutic potential of resveratrol: the in vivo evidence. | Joseph A Baur, David A Sinclair | Nat Rev Drug Discov | 2006 | 16732220 | No |
2536 | 4025 | 1341.7 | 90.69 | 30.2 | Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? | Witold Filipowicz, Suvendra N Bhattacharyya, Nahum Sonenberg | Nat Rev Genet | 2008 | 18197166 | No |
2537 | 1341 | 1341.0 | 80.91 | 80.9 | A comparison of canal preparations in straight and curved root canals. | S W Schneider | Oral Surg Oral Med Oral Pathol | 1971 | 5284110 | Yes |
2538 | 1341 | 1341.0 | 35.94 | 35.9 | Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects. | E B Hunziker | Osteoarthritis Cartilage | 2002 | 12056848 | No |
2539 | 4022 | 1340.7 | 136.26 | 45.4 | Job burnout. | C Maslach, W B Schaufeli, M P Leiter | Annu Rev Psychol | 2001 | 11148311 | Yes |
2540 | 2681 | 1340.5 | 86.18 | 43.1 | Plasma-high-density-lipoprotein concentration and development of ischaemic heart-disease. | G J Miller, N E Miller | Lancet | 1975 | 46338 | Yes |
2541 | 2681 | 1340.5 | 64.67 | 32.3 | Microglia: active sensor and versatile effector cells in the normal and pathologic brain. | Uwe-Karsten Hanisch, Helmut Kettenmann | Nat Neurosci | 2007 | 17965659 | No |
2542 | 2680 | 1340.0 | 60.06 | 30.0 | Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma. | G Blobel, B Dobberstein | J Cell Biol | 1975 | 811671 | Yes |
2543 | 1340 | 1340.0 | 35.59 | 35.6 | Fibronectin and its receptors. | E Ruoslahti | Annu Rev Biochem | 1988 | 2972252 | No |
2544 | 1340 | 1340.0 | 30.14 | 30.1 | Physiological and molecular basis of thyroid hormone action. | P M Yen | Physiol Rev | 2001 | 11427693 | No |
2545 | 1340 | 1340.0 | 22.97 | 23.0 | Protein modification by SUMO. | Erica S Johnson | Annu Rev Biochem | 2004 | 15189146 | No |
2546 | 2679 | 1339.5 | 71.22 | 35.6 | A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival. | B G Durie, S E Salmon | Cancer | 1975 | 1182674 | Yes |
2547 | 1338 | 1338.0 | 44.68 | 44.7 | Functional organization of central pathways regulating the cardiovascular system. | R A Dampney | Physiol Rev | 1994 | 8171117 | No |
2548 | 5352 | 1338.0 | 117.74 | 29.4 | Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. | Eugenia E Calle, Carmen Rodriguez, Kimberly Walker-Thurmond, Michael J Thun | N Engl J Med | 2003 | 12711737 | Yes |
2549 | 1338 | 1338.0 | 0.0 | 0.0 | The anterior approach for removal of ruptured cervical disks. | R B Cloward | J Neurosurg | 1958 | 13599052 | Yes |
2550 | 1337 | 1337.0 | 25.16 | 25.2 | A modified procedure for lead staining of thin sections. | G Millonig | J Biophys Biochem Cytol | 1961 | 14474176 | Yes |
2551 | 4010 | 1336.7 | 100.56 | 33.5 | LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions. | A C Wallace, R A Laskowski, J M Thornton | Protein Eng | 1995 | 7630882 | Yes |
2552 | 4009 | 1336.3 | 102.97 | 34.3 | Cognitive and emotional influences in anterior cingulate cortex. | G Bush, P Luu, M I Posner | Trends Cogn Sci | 2000 | 10827444 | Yes |
2553 | 1335 | 1335.0 | 33.99 | 34.0 | Thioredoxin and glutaredoxin systems. | A Holmgren | J Biol Chem | 1989 | 2668278 | No |
2554 | 1335 | 1335.0 | 34.9 | 34.9 | The molten globule state as a clue for understanding the folding and cooperativity of globular-protein structure. | K Kuwajima | Proteins | 1989 | 2695928 | No |
2555 | 1335 | 1335.0 | 28.43 | 28.4 | The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. | G B Morin | Cell | 1989 | 2805070 | Yes |
2556 | 1335 | 1335.0 | 47.01 | 47.0 | Neuropeptide Y: complete amino acid sequence of the brain peptide. | K Tatemoto | Proc Natl Acad Sci U S A | 1982 | 6957876 | Yes |
2557 | 1335 | 1335.0 | 41.69 | 41.7 | The phenomenon of the acute phase response. | I Kushner | Ann N Y Acad Sci | 1982 | 7046585 | No |
2558 | 1335 | 1335.0 | 33.29 | 33.3 | Comparative physiology of salt and water stress. | R. Munns | Plant Cell Environ | 2002 | 11841667 | Yes |
2559 | 2670 | 1335.0 | 63.47 | 31.7 | C-reactive protein: a critical update. | Mark B Pepys, Gideon M Hirschfield | J Clin Invest | 2003 | 12813013 | No |
2560 | 4005 | 1335.0 | 107.32 | 35.8 | Nitric oxide and peroxynitrite in health and disease. | Pál Pacher, Joseph S Beckman, Lucas Liaudet | Physiol Rev | 2007 | 17237348 | No |
2561 | 1335 | 1335.0 | 36.3 | 36.3 | Regulation of glutathione synthesis. | Shelly C Lu | Mol Aspects Med | 2009 | 18601945 | No |
2562 | 2669 | 1334.5 | 76.71 | 38.4 | Further improvements in the plaque technique for detecting single antibody-forming cells. | A J Cunningham, A Szenberg | Immunology | 1968 | 5653817 | Yes |
2563 | 2669 | 1334.5 | 76.6 | 38.3 | Alternatives for logistic regression in cross-sectional studies: an empirical comparison of models that directly estimate the prevalence ratio. | Aluísio J D Barros, Vânia N Hirakata | BMC Med Res Methodol | 2003 | 14567763 | Yes |
2564 | 2669 | 1334.5 | 59.21 | 29.6 | A comparison of bayesian methods for haplotype reconstruction from population genotype data. | Matthew Stephens, Peter Donnelly | Am J Hum Genet | 2003 | 14574645 | Yes |
2565 | 2668 | 1334.0 | 61.39 | 30.7 | Microenvironmental regulation of metastasis. | Johanna A Joyce, Jeffrey W Pollard | Nat Rev Cancer | 2009 | 19279573 | No |
2566 | 1334 | 1334.0 | 28.38 | 28.4 | Mechanisms of foxp3+ T regulatory cell-mediated suppression. | Ethan M Shevach | Immunity | 2009 | 19464986 | No |
2567 | 1333 | 1333.0 | 38.5 | 38.5 | Endometriosis. | Serdar E Bulun | N Engl J Med | 2009 | 19144942 | No |
2568 | 6663 | 1332.6 | 125.46 | 25.1 | Crystal structure of the nucleosome core particle at 2.8 A resolution. | K Luger, A W Mäder, R K Richmond, D F Sargent, T J Richmond | Nature | 1997 | 9305837 | Yes |
2569 | 1332 | 1332.0 | 25.66 | 25.7 | Stereological principles for morphometry in electron microscopic cytology. | E R Weibel | Int Rev Cytol | 1969 | 4899604 | No |
2570 | 1332 | 1332.0 | 35.56 | 35.6 | Levels of racism: a theoretic framework and a gardener's tale. | C P Jones | Am J Public Health | 2000 | 10936998 | Yes |
2571 | 1332 | 1332.0 | 23.39 | 23.4 | SUMO: a history of modification. | Ronald T Hay | Mol Cell | 2005 | 15808504 | No |
2572 | 1332 | 1332.0 | 32.76 | 32.8 | N-heterocyclic carbenes: a new concept in organometallic catalysis. | Wolfgang A Herrmann | Angew Chem Int Ed Engl | 2002 | 19750753 | Yes |
2573 | 2664 | 1332.0 | 58.47 | 29.2 | Breaking the diffraction resolution limit by stimulated emission: stimulated-emission-depletion fluorescence microscopy. | S W Hell, J Wichmann | Opt Lett | 1994 | 19844443 | Yes |
2574 | 1332 | 1332.0 | 61.45 | 61.5 | When to use the Bonferroni correction. | Richard A Armstrong | Ophthalmic Physiol Opt | 2014 | 24697967 | No |
2575 | 2663 | 1331.5 | 53.66 | 26.8 | Regulated portals of entry into the cell. | Sean D Conner, Sandra L Schmid | Nature | 2003 | 12621426 | No |
2576 | 2663 | 1331.5 | 78.08 | 39.0 | Insights into the regulation of protein abundance from proteomic and transcriptomic analyses. | Christine Vogel, Edward M Marcotte | Nat Rev Genet | 2012 | 22411467 | No |
2577 | 1331 | 1331.0 | 30.1 | 30.1 | Metastatic bone disease: clinical features, pathophysiology and treatment strategies. | R E Coleman | Cancer Treat Rev | 2001 | 11417967 | No |
2578 | 3993 | 1331.0 | 113.01 | 37.7 | The Patient Health Questionnaire-2: validity of a two-item depression screener. | Kurt Kroenke, Robert L Spitzer, Janet B W Williams | Med Care | 2003 | 14583691 | Yes |
2579 | 1330 | 1330.0 | 48.34 | 48.3 | The life and times of the Enterococcus. | B E Murray | Clin Microbiol Rev | 1990 | 2404568 | No |
2580 | 1330 | 1330.0 | 41.66 | 41.7 | Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data. | Thomas Heberer | Toxicol Lett | 2002 | 11988354 | Yes |
2581 | 3990 | 1330.0 | 102.93 | 34.3 | Bacterial biofilms: from the natural environment to infectious diseases. | Luanne Hall-Stoodley, J William Costerton, Paul Stoodley | Nat Rev Microbiol | 2004 | 15040259 | No |
2582 | 1330 | 1330.0 | 37.59 | 37.6 | Cytokinesis-block micronucleus cytome assay. | Michael Fenech | Nat Protoc | 2007 | 17546000 | Yes |
2583 | 5317 | 1329.2 | 130.45 | 32.6 | Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. | D W Cleveland, S G Fischer, M W Kirschner, U K Laemmli | J Biol Chem | 1977 | 320200 | Yes |
2584 | 1329 | 1329.0 | 42.88 | 42.9 | The epidemiology of adult obstructive sleep apnea. | Naresh M Punjabi | Proc Am Thorac Soc | 2008 | 18250205 | No |
2585 | 2658 | 1329.0 | 56.11 | 28.1 | The canonical Notch signaling pathway: unfolding the activation mechanism. | Raphael Kopan, Maria Xenia G Ilagan | Cell | 2009 | 19379690 | No |
2586 | 2656 | 1328.0 | 55.8 | 27.9 | Liver regeneration. | G K Michalopoulos, M C DeFrances | Science | 1997 | 9082986 | No |
2587 | 1328 | 1328.0 | 38.53 | 38.5 | Osteoblast adhesion on biomaterials. | K Anselme | Biomaterials | 2000 | 10711964 | No |
2588 | 2655 | 1327.5 | 68.32 | 34.2 | Apoptosis, oncosis, and necrosis. An overview of cell death. | G Majno, I Joris | Am J Pathol | 1995 | 7856735 | No |
2589 | 1327 | 1327.0 | 34.56 | 34.6 | The aryl hydrocarbon receptor complex. | O Hankinson | Annu Rev Pharmacol Toxicol | 1995 | 7598497 | No |
2590 | 6635 | 1327.0 | 248.47 | 49.7 | DNA primers for amplification of mitochondrial cytochrome c oxidase subunit I from diverse metazoan invertebrates. | O Folmer, M Black, W Hoeh, R Lutz, R Vrijenhoek | Mol Mar Biol Biotechnol | 1994 | 7881515 | Yes |
2591 | 2654 | 1327.0 | 46.68 | 23.3 | Rab proteins as membrane organizers. | M Zerial, H McBride | Nat Rev Mol Cell Biol | 2001 | 11252952 | No |
2592 | 1326 | 1326.0 | 29.94 | 29.9 | Functions of the neurotrophins during nervous system development: what the knockouts are teaching us. | W D Snider | Cell | 1994 | 8205613 | No |
2593 | 3978 | 1326.0 | 81.19 | 27.1 | Calcium signalling: dynamics, homeostasis and remodelling. | Michael J Berridge, Martin D Bootman, H Llewelyn Roderick | Nat Rev Mol Cell Biol | 2003 | 12838335 | No |
2594 | 1326 | 1326.0 | 0.0 | 0.0 | On the psychophysical law. | S S Stevens | Psychol Rev | 1957 | 13441853 | Yes |
2595 | 1326 | 1326.0 | 61.31 | 61.3 | Cellular resistance to infection. | G B Mackaness | J Exp Med | 1962 | 14467923 | Yes |
2596 | 1326 | 1326.0 | 79.69 | 79.7 | Information bias in health research: definition, pitfalls, and adjustment methods. | Alaa Althubaiti | J Multidiscip Healthc | 2016 | 27217764 | No |
2597 | 1325 | 1325.0 | 23.14 | 23.1 | Clonal selection and learning in the antibody system. | K Rajewsky | Nature | 1996 | 8657279 | No |
2598 | 2649 | 1324.5 | 57.61 | 28.8 | Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. | Jane E Visvader, Geoffrey J Lindeman | Nat Rev Cancer | 2008 | 18784658 | No |
2599 | 1324 | 1324.0 | 35.58 | 35.6 | Polycystic ovary syndrome. | David A Ehrmann | N Engl J Med | 2005 | 15788499 | No |
2600 | 1324 | 1324.0 | 27.33 | 27.3 | Neuroligins and neurexins link synaptic function to cognitive disease. | Thomas C Südhof | Nature | 2008 | 18923512 | No |
2601 | 7939 | 1323.2 | 198.18 | 33.0 | An obesity-associated gut microbiome with increased capacity for energy harvest. | Peter J Turnbaugh, Ruth E Ley, Michael A Mahowald, Vincent Magrini, Elaine R Mardis, Jeffrey I Gordon | Nature | 2006 | 17183312 | Yes |
2602 | 2646 | 1323.0 | 252.12 | 126.1 | Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019. | David J Newman, Gordon M Cragg | J Nat Prod | 2020 | 32162523 | No |
2603 | 2645 | 1322.5 | 118.0 | 59.0 | Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty. | J M Tanner, R H Whitehouse | Arch Dis Child | 1976 | 952550 | Yes |
2604 | 2645 | 1322.5 | 49.11 | 24.6 | New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. | R D Gietz, A Sugino | Gene | 1988 | 3073106 | Yes |
2605 | 2645 | 1322.5 | 100.63 | 50.3 | Enzyme-linked immunosorbent assay, Elisa. 3. Quantitation of specific antibodies by enzyme-labeled anti-immunoglobulin in antigen-coated tubes. | E Engvall, P Perlmann | J Immunol | 1972 | 4113792 | Yes |
2606 | 7935 | 1322.5 | 199.85 | 33.3 | Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research. | Ana Conesa, Stefan Götz, Juan Miguel García-Gómez, Javier Terol, Manuel Talón, Montserrat Robles | Bioinformatics | 2005 | 16081474 | Yes |
2607 | 6611 | 1322.2 | 259.82 | 52.0 | Integrating single-cell transcriptomic data across different conditions, technologies, and species. | Andrew Butler, Paul Hoffman, Peter Smibert, Efthymia Papalexi, Rahul Satija | Nat Biotechnol | 2018 | 29608179 | Yes |
2608 | 1322 | 1322.0 | 50.53 | 50.5 | Free-radical mechanisms in tissue injury. | T F Slater | Biochem J | 1984 | 6383353 | No |
2609 | 2644 | 1322.0 | 60.14 | 30.1 | Integrins and signal transduction pathways: the road taken. | E A Clark, J S Brugge | Science | 1995 | 7716514 | No |
2610 | 1322 | 1322.0 | 39.34 | 39.3 | Persister cells. | Kim Lewis | Annu Rev Microbiol | 2010 | 20528688 | No |
2611 | 1321 | 1321.0 | 54.85 | 54.9 | Error in medicine. | L L Leape | JAMA | 1994 | 7503827 | Yes |
2612 | 1321 | 1321.0 | 35.22 | 35.2 | Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. | Arnold I Caplan | J Cell Physiol | 2007 | 17620285 | No |
2613 | 1321 | 1321.0 | 32.12 | 32.1 | Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. | G L Semenza | Oncogene | 2010 | 19946328 | No |
2614 | 3962 | 1320.7 | 97.27 | 32.4 | The p53 tumour suppressor gene. | A J Levine, J Momand, C A Finlay | Nature | 1991 | 2046748 | No |
2615 | 3958 | 1319.3 | 141.42 | 47.1 | A new method for off-line removal of ocular artifact. | G Gratton, M G Coles, E Donchin | Electroencephalogr Clin Neurophysiol | 1983 | 6187540 | Yes |
2616 | 3958 | 1319.3 | 83.78 | 27.9 | A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. | R Medzhitov, P Preston-Hurlburt, C A Janeway | Nature | 1997 | 9237759 | Yes |
2617 | 1319 | 1319.0 | 22.86 | 22.9 | Regulatory T cells: key controllers of immunologic self-tolerance. | S Sakaguchi | Cell | 2000 | 10850488 | No |
2618 | 3956 | 1318.7 | 91.22 | 30.4 | Tissue cells feel and respond to the stiffness of their substrate. | Dennis E Discher, Paul Janmey, Yu-Li Wang | Science | 2005 | 16293750 | No |
2619 | 2636 | 1318.0 | 168.3 | 84.2 | Facial nerve grading system. | J W House, D E Brackmann | Otolaryngol Head Neck Surg | 1985 | 3921901 | Yes |
2620 | 1318 | 1318.0 | 17.08 | 17.1 | Disconnexion syndromes in animals and man. I. | N Geschwind | Brain | 1965 | 5318481 | No |
2621 | 2636 | 1318.0 | 56.59 | 28.3 | Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information. | M Zuker, P Stiegler | Nucleic Acids Res | 1981 | 6163133 | Yes |
2622 | 1318 | 1318.0 | 31.51 | 31.5 | Apoptosis in cancer therapy: crossing the threshold. | D E Fisher | Cell | 1994 | 8069905 | No |
2623 | 5272 | 1318.0 | 104.65 | 26.2 | Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. | D D Sarbassov, David A Guertin, Siraj M Ali, David M Sabatini | Science | 2005 | 15718470 | Yes |
2624 | 1317 | 1317.0 | 22.5 | 22.5 | Extraordinary sex ratios. A sex-ratio theory for sex linkage and inbreeding has new implications in cytogenetics and entomology. | W D Hamilton | Science | 1967 | 6021675 | Yes |
2625 | 5268 | 1317.0 | 123.53 | 30.9 | Improved prediction of signal peptides: SignalP 3.0. | Jannick Dyrløv Bendtsen, Henrik Nielsen, Gunnar von Heijne, Søren Brunak | J Mol Biol | 2004 | 15223320 | Yes |
2626 | 1317 | 1317.0 | 34.09 | 34.1 | The sympathetic control of blood pressure. | Patrice G Guyenet | Nat Rev Neurosci | 2006 | 16760914 | No |
2627 | 2632 | 1316.0 | 101.05 | 50.5 | Malondialdehyde determination as index of lipid peroxidation. | H H Draper, M Hadley | Methods Enzymol | 1990 | 2233309 | Yes |
2628 | 1316 | 1316.0 | 69.83 | 69.8 | Psychosocial resilience and protective mechanisms. | Michael Rutter | Am J Orthopsychiatry | 1987 | 3303954 | No |
2629 | 1316 | 1316.0 | 44.14 | 44.1 | Carnitine--metabolism and functions. | J Bremer | Physiol Rev | 1983 | 6361812 | No |
2630 | 1316 | 1316.0 | 43.86 | 43.9 | Enhancing the quality and credibility of qualitative analysis. | M Q Patton | Health Serv Res | 1999 | 10591279 | No |
2631 | 1316 | 1316.0 | 28.58 | 28.6 | Long-term potentiation and memory. | M A Lynch | Physiol Rev | 2004 | 14715912 | No |
2632 | 3948 | 1316.0 | 93.12 | 31.0 | Functional porous coordination polymers. | Susumu Kitagawa, Ryo Kitaura, Shin-ichiro Noro | Angew Chem Int Ed Engl | 2004 | 15114565 | Yes |
2633 | 1316 | 1316.0 | 38.73 | 38.7 | Gadolinium--a specific trigger for the development of nephrogenic fibrosing dermopathy and nephrogenic systemic fibrosis? | Thomas Grobner | Nephrol Dial Transplant | 2006 | 16431890 | Yes |
2634 | 2632 | 1316.0 | 67.82 | 33.9 | Integrins in cancer: biological implications and therapeutic opportunities. | Jay S Desgrosellier, David A Cheresh | Nat Rev Cancer | 2010 | 20029421 | No |
2635 | 1316 | 1316.0 | 41.17 | 41.2 | Function and information content of DNA methylation. | Dirk Schübeler | Nature | 2015 | 25592537 | No |
2636 | 1315 | 1315.0 | 24.57 | 24.6 | Antigen-specific interaction between T and B cells. | A Lanzavecchia | Nature | 1985 | 3157869 | Yes |
2637 | 2630 | 1315.0 | 84.12 | 42.1 | The short-form version of the Depression Anxiety Stress Scales (DASS-21): construct validity and normative data in a large non-clinical sample. | Julie D Henry, John R Crawford | Br J Clin Psychol | 2005 | 16004657 | Yes |
2638 | 1315 | 1315.0 | 40.71 | 40.7 | Thermal properties of graphene and nanostructured carbon materials. | Alexander A Balandin | Nat Mater | 2011 | 21778997 | Yes |
2639 | 6571 | 1314.2 | 157.84 | 31.6 | Jalview Version 2--a multiple sequence alignment editor and analysis workbench. | Andrew M Waterhouse, James B Procter, David M A Martin, Michèle Clamp, Geoffrey J Barton | Bioinformatics | 2009 | 19151095 | Yes |
2640 | 1314 | 1314.0 | 33.11 | 33.1 | Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders. | R M Sapolsky | Arch Gen Psychiatry | 2000 | 11015810 | No |
2641 | 1314 | 1314.0 | 53.82 | 53.8 | Inflammation, metaflammation and immunometabolic disorders. | Gökhan S Hotamisligil | Nature | 2017 | 28179656 | No |
2642 | 2626 | 1313.0 | 38.25 | 19.1 | Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. | J E Sulston, H R Horvitz | Dev Biol | 1977 | 838129 | Yes |
2643 | 1313 | 1313.0 | 33.4 | 33.4 | Supported membranes: scientific and practical applications. | E Sackmann | Science | 1996 | 8539599 | No |
2644 | 1313 | 1313.0 | 42.25 | 42.2 | An application of prefrontal cortex function theory to cognitive aging. | R L West | Psychol Bull | 1996 | 8831298 | No |
2645 | 1313 | 1313.0 | 33.6 | 33.6 | Psychological and neural mechanisms of the affective dimension of pain. | D D Price | Science | 2000 | 10846154 | No |
2646 | 1313 | 1313.0 | 27.77 | 27.8 | Prediction of protein cellular attributes using pseudo-amino acid composition. | K C Chou | Proteins | 2001 | 11288174 | Yes |
2647 | 2624 | 1312.0 | 77.13 | 38.6 | Prediction of the secondary structure of proteins from their amino acid sequence. | P Y Chou, G D Fasman | Adv Enzymol Relat Areas Mol Biol | 1978 | 364941 | No |
2648 | 2624 | 1312.0 | 58.46 | 29.2 | The codon Adaptation Index--a measure of directional synonymous codon usage bias, and its potential applications. | P M Sharp, W H Li | Nucleic Acids Res | 1987 | 3547335 | Yes |
2649 | 1312 | 1312.0 | 37.3 | 37.3 | Qinghaosu (artemisinin): an antimalarial drug from China. | D L Klayman | Science | 1985 | 3887571 | No |
2650 | 1312 | 1312.0 | 0.0 | 0.0 | Limitations of the application of fourfold table analysis to hospital data. | J Berkson | Biometrics | 1946 | 21001024 | Yes |
2651 | 1312 | 1312.0 | 45.05 | 45.0 | PaDEL-descriptor: an open source software to calculate molecular descriptors and fingerprints. | Chun Wei Yap | J Comput Chem | 2011 | 21425294 | Yes |
2652 | 1311 | 1311.0 | 38.24 | 38.2 | Stimulus-secretion coupling: the concept and clues from chromaffin and other cells. | W W Douglas | Br J Pharmacol | 1968 | 4882190 | No |
2653 | 1311 | 1311.0 | 0.0 | 0.0 | Analyzer for accurate estimation of respiratory gases in one-half cubic centimeter samples. | P F Scholander | J Biol Chem | 1947 | 20281644 | Yes |
2654 | 1311 | 1311.0 | 56.73 | 56.7 | Canadian Diabetes Association 2013 clinical practice guidelines for the prevention and management of diabetes in Canada. Introduction. | Alice Y Y Cheng | Can J Diabetes | 2013 | 24070926 | No |
2655 | 1310 | 1310.0 | 37.25 | 37.2 | The matrix-degrading metalloproteinases. | L M Matrisian | Bioessays | 1992 | 1445287 | No |
2656 | 1310 | 1310.0 | 35.77 | 35.8 | The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions. | R G Gerrity | Am J Pathol | 1981 | 7234961 | Yes |
2657 | 2620 | 1310.0 | 60.64 | 30.3 | Quorum sensing in bacteria. | M B Miller, B L Bassler | Annu Rev Microbiol | 2001 | 11544353 | No |
2658 | 3930 | 1310.0 | 88.0 | 29.3 | Photodynamic therapy for cancer. | Dennis E J G J Dolmans, Dai Fukumura, Rakesh K Jain | Nat Rev Cancer | 2003 | 12724736 | No |
2659 | 3929 | 1309.7 | 91.31 | 30.4 | Evolution and functions of long noncoding RNAs. | Chris P Ponting, Peter L Oliver, Wolf Reik | Cell | 2009 | 19239885 | No |
2660 | 2619 | 1309.5 | 40.23 | 20.1 | The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites. | J Shine, L Dalgarno | Proc Natl Acad Sci U S A | 1974 | 4598299 | Yes |
2661 | 2618 | 1309.0 | 49.16 | 24.6 | Immunization of dissociated spleen cell cultures from normal mice. | R I Mishell, R W Dutton | J Exp Med | 1967 | 6034749 | Yes |
2662 | 1309 | 1309.0 | 41.82 | 41.8 | How stigma interferes with mental health care. | Patrick Corrigan | Am Psychol | 2004 | 15491256 | Yes |
2663 | 1309 | 1309.0 | 41.67 | 41.7 | Photoplethysmography and its application in clinical physiological measurement. | John Allen | Physiol Meas | 2007 | 17322588 | No |
2664 | 1309 | 1309.0 | 38.06 | 38.1 | Federal funding for the study of antimicrobial resistance in nosocomial pathogens: no ESKAPE. | Louis B Rice | J Infect Dis | 2008 | 18419525 | No |
2665 | 2617 | 1308.5 | 59.5 | 29.8 | Supercoil sequencing: a fast and simple method for sequencing plasmid DNA. | E Y Chen, P H Seeburg | DNA | 1985 | 3996185 | Yes |
2666 | 2616 | 1308.0 | 44.94 | 22.5 | Functions of lysosomes. | C De Duve, R Wattiaux | Annu Rev Physiol | 1966 | 5322983 | No |
2667 | 5229 | 1307.2 | 114.52 | 28.6 | A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes. | Vsevolod V Rostovtsev, Luke G Green, Valery V Fokin, K Barry Sharpless | Angew Chem Int Ed Engl | 2002 | 12203546 | Yes |
2668 | 1307 | 1307.0 | 27.63 | 27.6 | Double identity for proteins of the Bcl-2 family. | J C Reed | Nature | 1997 | 9194558 | No |
2669 | 1307 | 1307.0 | 32.14 | 32.1 | Overview of general physiologic features and functions of vitamin D. | Hector F DeLuca | Am J Clin Nutr | 2004 | 15585789 | No |
2670 | 1306 | 1306.0 | 34.53 | 34.5 | Phylogenies from molecular sequences: inference and reliability. | J Felsenstein | Annu Rev Genet | 1988 | 3071258 | No |
2671 | 1306 | 1306.0 | 0.0 | 0.0 | A quantitative immunochemical measure of the primary interaction between I BSA and antibody. | R S Farr | J Infect Dis | 1958 | 13611294 | Yes |
2672 | 1306 | 1306.0 | 24.15 | 24.1 | Mobile elements: drivers of genome evolution. | Haig H Kazazian | Science | 2004 | 15016989 | No |
2673 | 1306 | 1306.0 | 46.94 | 46.9 | Energy metabolism in the liver. | Liangyou Rui | Compr Physiol | 2014 | 24692138 | No |
2674 | 2611 | 1305.5 | 87.57 | 43.8 | Factors affecting wound healing. | S Guo, L A Dipietro | J Dent Res | 2010 | 20139336 | No |
2675 | 1305 | 1305.0 | 29.77 | 29.8 | The prefrontal cortex and cognitive control. | E K Miller | Nat Rev Neurosci | 2000 | 11252769 | No |
2676 | 1305 | 1305.0 | 32.98 | 33.0 | Pain and emotion interactions in subregions of the cingulate gyrus. | Brent A Vogt | Nat Rev Neurosci | 2005 | 15995724 | No |
2677 | 2609 | 1304.5 | 64.81 | 32.4 | Interneurons of the hippocampus. | T F Freund, G Buzsáki | Hippocampus | 1996 | 8915675 | No |
2678 | 2609 | 1304.5 | 0.0 | 0.0 | Construct validity in psychological tests. | L J Cronbach, P E Meehl | Psychol Bull | 1955 | 13245896 | Yes |
2679 | 6522 | 1304.4 | 160.0 | 32.0 | Enzymatic determination of total serum cholesterol. | C C Allain, L S Poon, C S Chan, W Richmond, P C Fu | Clin Chem | 1974 | 4818200 | Yes |
2680 | 1304 | 1304.0 | 31.78 | 31.8 | Surrogate endpoints in clinical trials: definition and operational criteria. | R L Prentice | Stat Med | 1989 | 2727467 | Yes |
2681 | 1304 | 1304.0 | 35.49 | 35.5 | Neural simulation of action: a unifying mechanism for motor cognition. | M Jeannerod | Neuroimage | 2001 | 11373140 | No |
2682 | 1303 | 1303.0 | 39.4 | 39.4 | Understanding diagnostic tests 3: Receiver operating characteristic curves. | Anthony K Akobeng | Acta Paediatr | 2007 | 17376185 | No |
2683 | 14330 | 1302.7 | 368.2 | 33.5 | Frailty in older adults: evidence for a phenotype. | L P Fried, C M Tangen, J Walston, A B Newman, C Hirsch, J Gottdiener, T Seeman, R Tracy, W J Kop, G Burke, M A McBurnie | J Gerontol A Biol Sci Med Sci | 2001 | 11253156 | Yes |
2684 | 2605 | 1302.5 | 69.72 | 34.9 | Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. | Taro Kawai, Shizuo Akira | Immunity | 2011 | 21616434 | No |
2685 | 2604 | 1302.0 | 43.26 | 21.6 | Genetic transformation of Drosophila with transposable element vectors. | G M Rubin, A C Spradling | Science | 1982 | 6289436 | Yes |
2686 | 1301 | 1301.0 | 32.3 | 32.3 | TNF-mediated inflammatory disease. | J R Bradley | J Pathol | 2008 | 18161752 | No |
2687 | 1301 | 1301.0 | 27.02 | 27.0 | Recognition and processing of ubiquitin-protein conjugates by the proteasome. | Daniel Finley | Annu Rev Biochem | 2009 | 19489727 | No |
2688 | 1301 | 1301.0 | 57.4 | 57.4 | The problem with the phrase women and minorities: intersectionality-an important theoretical framework for public health. | Lisa Bowleg | Am J Public Health | 2012 | 22594719 | Yes |
2689 | 9101 | 1300.1 | 312.39 | 44.6 | Metagenomic biomarker discovery and explanation. | Nicola Segata, Jacques Izard, Levi Waldron, Dirk Gevers, Larisa Miropolsky, Wendy S Garrett, Curtis Huttenhower | Genome Biol | 2011 | 21702898 | Yes |
2690 | 1300 | 1300.0 | 34.49 | 34.5 | The biochemistry and medical significance of the flavonoids. | Bent H Havsteen | Pharmacol Ther | 2002 | 12453566 | No |
2691 | 1300 | 1300.0 | 0.0 | 0.0 | On the local reactions of the arterial wall to changes of internal pressure. | W M Bayliss | J Physiol | 1902 | 16992618 | Yes |
2692 | 2598 | 1299.0 | 83.04 | 41.5 | Epidermal growth factor. | G Carpenter, S Cohen | Annu Rev Biochem | 1979 | 382984 | No |
2693 | 1299 | 1299.0 | 28.22 | 28.2 | Liver fibrosis -- from bench to bedside. | Scott L Friedman | J Hepatol | 2003 | 12591185 | No |
2694 | 2598 | 1299.0 | 0.0 | 0.0 | Primary carcinoma of the liver: a study of 100 cases among 48,900 necropsies. | H A Edmondson, P E Steiner | Cancer | 1954 | 13160935 | Yes |
2695 | 1299 | 1299.0 | 29.98 | 30.0 | Pathways of oxidative damage. | James A Imlay | Annu Rev Microbiol | 2003 | 14527285 | No |
2696 | 1299 | 1299.0 | 47.92 | 47.9 | Glutathione synthesis. | Shelly C Lu | Biochim Biophys Acta | 2013 | 22995213 | No |
2697 | 1298 | 1298.0 | 44.56 | 44.6 | The theoretical bases of indirect calorimetry: a review. | E Ferrannini | Metabolism | 1988 | 3278194 | No |
2698 | 2596 | 1298.0 | 131.36 | 65.7 | A study of the natural history of back pain. Part I: development of a reliable and sensitive measure of disability in low-back pain. | M Roland, R Morris | Spine (Phila Pa 1976) | 1983 | 6222486 | Yes |
2699 | 1298 | 1298.0 | 43.8 | 43.8 | Density matrix formulation for quantum renormalization groups. | S R White | Phys Rev Lett | 1992 | 10046608 | Yes |
2700 | 1298 | 1298.0 | 30.29 | 30.3 | Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. | Hiroshi Takayanagi | Nat Rev Immunol | 2007 | 17380158 | No |
2701 | 1298 | 1298.0 | 24.12 | 24.1 | ChIP-seq: advantages and challenges of a maturing technology. | Peter J Park | Nat Rev Genet | 2009 | 19736561 | No |
2702 | 3892 | 1297.3 | 126.91 | 42.3 | Rehospitalizations among patients in the Medicare fee-for-service program. | Stephen F Jencks, Mark V Williams, Eric A Coleman | N Engl J Med | 2009 | 19339721 | Yes |
2703 | 2594 | 1297.0 | 71.43 | 35.7 | What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience? | K C Berridge, T E Robinson | Brain Res Brain Res Rev | 1998 | 9858756 | No |
2704 | 1297 | 1297.0 | 23.32 | 23.3 | CD95's deadly mission in the immune system. | P H Krammer | Nature | 2000 | 11048730 | No |
2705 | 2593 | 1296.5 | 61.58 | 30.8 | Multipoint quantitative-trait linkage analysis in general pedigrees. | L Almasy, J Blangero | Am J Hum Genet | 1998 | 9545414 | Yes |
2706 | 1296 | 1296.0 | 31.0 | 31.0 | Receptors for epidermal growth factor and other polypeptide mitogens. | G Carpenter | Annu Rev Biochem | 1987 | 3039909 | No |
2707 | 1296 | 1296.0 | 45.3 | 45.3 | Plasma perspective on strong field multiphoton ionization. | P B Corkum | Phys Rev Lett | 1993 | 10054556 | Yes |
2708 | 1296 | 1296.0 | 29.52 | 29.5 | Oxyradicals and DNA damage. | L J Marnett | Carcinogenesis | 2000 | 10688856 | No |
2709 | 1296 | 1296.0 | 22.56 | 22.6 | The molecular motor toolbox for intracellular transport. | Ronald D Vale | Cell | 2003 | 12600311 | No |
2710 | 1296 | 1296.0 | 35.64 | 35.6 | Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes--a meta-analysis. | P Vestergaard | Osteoporos Int | 2007 | 17068657 | No |
2711 | 1296 | 1296.0 | 33.77 | 33.8 | Bacteroides: the good, the bad, and the nitty-gritty. | Hannah M Wexler | Clin Microbiol Rev | 2007 | 17934076 | No |
2712 | 1296 | 1296.0 | 35.63 | 35.6 | T follicular helper cell differentiation, function, and roles in disease. | Shane Crotty | Immunity | 2014 | 25367570 | No |
2713 | 6477 | 1295.4 | 248.98 | 49.8 | The Phyre2 web portal for protein modeling, prediction and analysis. | Lawrence A Kelley, Stefans Mezulis, Christopher M Yates, Mark N Wass, Michael J E Sternberg | Nat Protoc | 2015 | 25950237 | Yes |
2714 | 3886 | 1295.3 | 143.4 | 47.8 | Visible light photoredox catalysis with transition metal complexes: applications in organic synthesis. | Christopher K Prier, Danica A Rankic, David W C MacMillan | Chem Rev | 2013 | 23509883 | No |
2715 | 1295 | 1295.0 | 31.16 | 31.2 | Papillomavirus infections--a major cause of human cancers. | H zur Hausen | Biochim Biophys Acta | 1996 | 8876633 | No |
2716 | 1295 | 1295.0 | 29.53 | 29.5 | The path to ubiquitous and low-cost organic electronic appliances on plastic. | Stephen R Forrest | Nature | 2004 | 15118718 | Yes |
2717 | 2590 | 1295.0 | 94.5 | 47.2 | Liposomal drug delivery systems: from concept to clinical applications. | Theresa M Allen, Pieter R Cullis | Adv Drug Deliv Rev | 2013 | 23036225 | No |
2718 | 1295 | 1295.0 | 101.76 | 101.8 | COVID-19 and African Americans. | Clyde W Yancy | JAMA | 2020 | 32293639 | Yes |
2719 | 2589 | 1294.5 | 98.6 | 49.3 | Cronbach's alpha. | J M Bland, D G Altman | BMJ | 1997 | 9055718 | Yes |
2720 | 3883 | 1294.3 | 74.84 | 24.9 | Exosomes: composition, biogenesis and function. | Clotilde Théry, Laurence Zitvogel, Sebastian Amigorena | Nat Rev Immunol | 2002 | 12154376 | No |
2721 | 2588 | 1294.0 | 58.84 | 29.4 | Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. | Kornelia Polyak, Robert A Weinberg | Nat Rev Cancer | 2009 | 19262571 | No |
2722 | 1293 | 1293.0 | 42.6 | 42.6 | Ruthenium red and violet. I. Chemistry, purification, methods of use for electron microscopy and mechanism of action. | J H Luft | Anat Rec | 1971 | 4108333 | Yes |
2723 | 1293 | 1293.0 | 29.21 | 29.2 | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. | Nigel Unwin | J Mol Biol | 2005 | 15701510 | Yes |
2724 | 1293 | 1293.0 | 79.68 | 79.7 | SARS-CoV-2 vaccines in development. | Florian Krammer | Nature | 2020 | 32967006 | No |
2725 | 1292 | 1292.0 | 41.63 | 41.6 | Electrophoretic separation of plasma lipoproteins in agarose gel. | R P Noble | J Lipid Res | 1968 | 4176473 | Yes |
2726 | 1292 | 1292.0 | 61.53 | 61.5 | Cardiovascular and renal actions of dopamine: potential clinical applications. | L I Goldberg | Pharmacol Rev | 1972 | 4554480 | No |
2727 | 1291 | 1291.0 | 36.05 | 36.0 | A Wilcoxon-type test for trend. | J Cuzick | Stat Med | 1985 | 3992076 | Yes |
2728 | 1291 | 1291.0 | 26.95 | 26.9 | Nucleic acid junctions and lattices. | N C Seeman | J Theor Biol | 1982 | 6188926 | Yes |
2729 | 2582 | 1291.0 | 63.62 | 31.8 | Neuronal plasticity: increasing the gain in pain. | C J Woolf, M W Salter | Science | 2000 | 10846153 | No |
2730 | 1291 | 1291.0 | 26.95 | 26.9 | The stem-cell niche as an entity of action. | David T Scadden | Nature | 2006 | 16810242 | No |
2731 | 1291 | 1291.0 | 33.76 | 33.8 | Persister cells, dormancy and infectious disease. | Kim Lewis | Nat Rev Microbiol | 2007 | 17143318 | No |
2732 | 1291 | 1291.0 | 37.38 | 37.4 | Species concepts and species delimitation. | Kevin De Queiroz | Syst Biol | 2007 | 18027281 | Yes |
2733 | 2581 | 1290.5 | 45.87 | 22.9 | DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. | Christopher J Bakkenist, Michael B Kastan | Nature | 2003 | 12556884 | Yes |
2734 | 2580 | 1290.0 | 89.57 | 44.8 | Surgical risk as related to time of intervention in the repair of intracranial aneurysms. | W E Hunt, R M Hess | J Neurosurg | 1968 | 5635959 | Yes |
2735 | 1290 | 1290.0 | 10.65 | 10.7 | Metabolic stability and epigenesis in randomly constructed genetic nets. | S A Kauffman | J Theor Biol | 1969 | 5803332 | Yes |
2736 | 3869 | 1289.7 | 97.28 | 32.4 | Atomic force microscope. | G Binnig, C F Quate, C Gerber | Phys Rev Lett | 1986 | 10033323 | Yes |
2737 | 2579 | 1289.5 | 55.3 | 27.6 | Mitochondrial control of cell death. | G Kroemer, J C Reed | Nat Med | 2000 | 10802706 | No |
2738 | 1289 | 1289.0 | 31.83 | 31.8 | The mitochondrial electron transport and oxidative phosphorylation system. | Y Hatefi | Annu Rev Biochem | 1985 | 2862839 | No |
2739 | 1289 | 1289.0 | 31.86 | 31.9 | Optimal experimental design for event-related fMRI. | A M Dale | Hum Brain Mapp | 1999 | 10524601 | Yes |
2740 | 2578 | 1289.0 | 46.65 | 23.3 | Live or let die: the cell's response to p53. | Karen H Vousden, Xin Lu | Nat Rev Cancer | 2002 | 12154352 | No |
2741 | 1289 | 1289.0 | 32.23 | 32.2 | Plasmonics: merging photonics and electronics at nanoscale dimensions. | Ekmel Ozbay | Science | 2006 | 16410515 | Yes |
2742 | 14170 | 1288.2 | 380.48 | 34.6 | The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. | Aram V Chobanian, George L Bakris, Henry R Black, William C Cushman, Lee A Green, Joseph L Izzo, Daniel W Jones, Barry J Materson, Suzanne Oparil, Jackson T Wright, Edward J Roccella | JAMA | 2003 | 12748199 | No |
2743 | 1288 | 1288.0 | 38.98 | 39.0 | Diversity and ubiquity of K channels. | B Rudy | Neuroscience | 1988 | 2457185 | No |
2744 | 2576 | 1288.0 | 67.16 | 33.6 | Integrating QTL mapping and genome scans towards the characterization of candidate loci under parallel selection in the lake whitefish (Coregonus clupeaformis). | S M Rogers, L Bernatchez | Mol Ecol | 2005 | 15660930 | Yes |
2745 | 5149 | 1287.2 | 183.55 | 45.9 | The chemistry and applications of metal-organic frameworks. | Hiroyasu Furukawa, Kyle E Cordova, Michael O'Keeffe, Omar M Yaghi | Science | 2013 | 23990564 | Yes |
2746 | 1287 | 1287.0 | 61.08 | 61.1 | New norms of upper limb fat and muscle areas for assessment of nutritional status. | A R Frisancho | Am J Clin Nutr | 1981 | 6975564 | Yes |
2747 | 2574 | 1287.0 | 67.25 | 33.6 | Epidemiology and outcomes of osteoporotic fractures. | Steven R Cummings, L Joseph Melton | Lancet | 2002 | 12049882 | No |
2748 | 2574 | 1287.0 | 64.86 | 32.4 | An integrative theory of locus coeruleus-norepinephrine function: adaptive gain and optimal performance. | Gary Aston-Jones, Jonathan D Cohen | Annu Rev Neurosci | 2005 | 16022602 | No |
2749 | 1287 | 1287.0 | 34.66 | 34.7 | How brains beware: neural mechanisms of emotional attention. | Patrik Vuilleumier | Trends Cogn Sci | 2005 | 16289871 | Yes |
2750 | 2572 | 1286.0 | 88.55 | 44.3 | Regulatory sequences involved in the promotion and termination of RNA transcription. | M Rosenberg, D Court | Annu Rev Genet | 1979 | 94251 | No |
2751 | 1286 | 1286.0 | 35.27 | 35.3 | Isolation of leucocytes from human blood. Further observations. Methylcellulose, dextran, and ficoll as erythrocyteaggregating agents. | A Böyum | Scand J Clin Lab Invest Suppl | 1968 | 4179066 | Yes |
2752 | 1286 | 1286.0 | 27.3 | 27.3 | Sustainable hydrogen production. | John A Turner | Science | 2004 | 15310892 | Yes |
2753 | 2572 | 1286.0 | 89.41 | 44.7 | Nitric oxide synthases: regulation and function. | Ulrich Förstermann, William C Sessa | Eur Heart J | 2012 | 21890489 | No |
2754 | 3857 | 1285.7 | 91.73 | 30.6 | Dystrophin: the protein product of the Duchenne muscular dystrophy locus. | E P Hoffman, R H Brown, L M Kunkel | Cell | 1987 | 3319190 | Yes |
2755 | 2571 | 1285.5 | 99.04 | 49.5 | Unique features of long non-coding RNA biogenesis and function. | Jeffrey J Quinn, Howard Y Chang | Nat Rev Genet | 2016 | 26666209 | No |
2756 | 1285 | 1285.0 | 46.91 | 46.9 | Substance P. | B Pernow | Pharmacol Rev | 1983 | 6196797 | No |
2757 | 1285 | 1285.0 | 30.36 | 30.4 | Lymphokine production by human T cells in disease states. | S Romagnani | Annu Rev Immunol | 1994 | 8011282 | No |
2758 | 1285 | 1285.0 | 35.91 | 35.9 | Deconvoluting the context-dependent role for autophagy in cancer. | Eileen White | Nat Rev Cancer | 2012 | 22534666 | No |
2759 | 1284 | 1284.0 | 21.77 | 21.8 | Cancer susceptibility and the functions of BRCA1 and BRCA2. | Ashok R Venkitaraman | Cell | 2002 | 11832208 | No |
2760 | 2568 | 1284.0 | 51.92 | 26.0 | Tumorigenesis and the angiogenic switch. | Gabriele Bergers, Laura E Benjamin | Nat Rev Cancer | 2003 | 12778130 | No |
2761 | 1284 | 1284.0 | 31.39 | 31.4 | Hydrogen sulphide and its therapeutic potential. | Csaba Szabó | Nat Rev Drug Discov | 2007 | 17948022 | No |
2762 | 3848 | 1282.7 | 172.14 | 57.4 | In search of how people change. Applications to addictive behaviors. | J O Prochaska, C C DiClemente, J C Norcross | Am Psychol | 1992 | 1329589 | Yes |
2763 | 2565 | 1282.5 | 156.52 | 78.3 | A joint coordinate system for the clinical description of three-dimensional motions: application to the knee. | E S Grood, W J Suntay | J Biomech Eng | 1983 | 6865355 | Yes |
2764 | 2565 | 1282.5 | 79.64 | 39.8 | Modeling and comparison of dissolution profiles. | P Costa, J M Sousa Lobo | Eur J Pharm Sci | 2001 | 11297896 | No |
2765 | 1282 | 1282.0 | 42.61 | 42.6 | Bee and wasp venoms. | E Habermann | Science | 1972 | 4113805 | No |
2766 | 1282 | 1282.0 | 82.21 | 82.2 | Epidemiology of Prostate Cancer. | Prashanth Rawla | World J Oncol | 2019 | 31068988 | No |
2767 | 2563 | 1281.5 | 213.48 | 106.7 | Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: retrospective and prospective analyses. | R B Gustilo, J T Anderson | J Bone Joint Surg Am | 1976 | 773941 | Yes |
2768 | 2563 | 1281.5 | 54.53 | 27.3 | The pathophysiology of mitochondrial cell death. | Douglas R Green, Guido Kroemer | Science | 2004 | 15286356 | No |
2769 | 2562 | 1281.0 | 60.77 | 30.4 | Production of single-stranded plasmid DNA. | J Vieira, J Messing | Methods Enzymol | 1987 | 3323803 | Yes |
2770 | 1281 | 1281.0 | 36.37 | 36.4 | Plant productivity and environment. | J S Boyer | Science | 1982 | 17808529 | Yes |
2771 | 8967 | 1281.0 | 250.77 | 35.8 | Cancer statistics, 2008. | Ahmedin Jemal, Rebecca Siegel, Elizabeth Ward, Yongping Hao, Jiaquan Xu, Taylor Murray, Michael J Thun | CA Cancer J Clin | 2008 | 18287387 | Yes |
2772 | 2561 | 1280.5 | 65.96 | 33.0 | Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. | J A Ledbetter, L A Herzenberg | Immunol Rev | 1979 | 398327 | No |
2773 | 2561 | 1280.5 | 62.84 | 31.4 | The free radical theory of aging matures. | K B Beckman, B N Ames | Physiol Rev | 1998 | 9562038 | No |
2774 | 20488 | 1280.5 | 576.19 | 36.0 | New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). | E A Eisenhauer, P Therasse, J Bogaerts, L H Schwartz, D Sargent, R Ford, J Dancey, S Arbuck, S Gwyther, M Mooney, L Rubinstein, L Shankar, L Dodd, R Kaplan, D Lacombe, J Verweij | Eur J Cancer | 2009 | 19097774 | No |
2775 | 2561 | 1280.5 | 97.32 | 48.7 | Kraken: ultrafast metagenomic sequence classification using exact alignments. | Derrick E Wood, Steven L Salzberg | Genome Biol | 2014 | 24580807 | Yes |
2776 | 1280 | 1280.0 | 28.99 | 29.0 | Chemistry and biology of the immunophilins and their immunosuppressive ligands. | S L Schreiber | Science | 1991 | 1702904 | No |
2777 | 1280 | 1280.0 | 49.85 | 49.9 | Geriatric Depression Scale. | J A Yesavage | Psychopharmacol Bull | 1988 | 3249773 | Yes |
2778 | 1280 | 1280.0 | 56.29 | 56.3 | Biomaterial-centered infection: microbial adhesion versus tissue integration. | A G Gristina | Science | 1987 | 3629258 | Yes |
2779 | 1280 | 1280.0 | 39.48 | 39.5 | Somatostatin. | S Reichlin | N Engl J Med | 1983 | 6139753 | No |
2780 | 1280 | 1280.0 | 0.0 | 0.0 | Agammaglobulinemia. | O C Bruton | Pediatrics | 1952 | 14929630 | Yes |
2781 | 2560 | 1280.0 | 89.51 | 44.8 | Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. | John F Cryan, Timothy G Dinan | Nat Rev Neurosci | 2012 | 22968153 | No |
2782 | 3839 | 1279.7 | 113.75 | 37.9 | Health benefits of physical activity: the evidence. | Darren E R Warburton, Crystal Whitney Nicol, Shannon S D Bredin | CMAJ | 2006 | 16534088 | No |
2783 | 2559 | 1279.5 | 52.6 | 26.3 | The molecular biology of axon guidance. | M Tessier-Lavigne, C S Goodman | Science | 1996 | 8895455 | No |
2784 | 8956 | 1279.4 | 264.61 | 37.8 | Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. | H P Adams, B H Bendixen, L J Kappelle, J Biller, B B Love, D L Gordon, E E Marsh | Stroke | 1993 | 7678184 | Yes |
2785 | 1279 | 1279.0 | 34.61 | 34.6 | Internal models for motor control and trajectory planning. | M Kawato | Curr Opin Neurobiol | 1999 | 10607637 | No |
2786 | 5116 | 1279.0 | 189.26 | 47.3 | Predicting effective microRNA target sites in mammalian mRNAs. | Vikram Agarwal, George W Bell, Jin-Wu Nam, David P Bartel | Elife | 2015 | 26267216 | Yes |
2787 | 2557 | 1278.5 | 81.88 | 40.9 | Oxidative mechanisms in the toxicity of metal ions. | S J Stohs, D Bagchi | Free Radic Biol Med | 1995 | 7744317 | No |
2788 | 1278 | 1278.0 | 28.76 | 28.8 | Evaluating medication effects outside of clinical trials: new-user designs. | Wayne A Ray | Am J Epidemiol | 2003 | 14585769 | Yes |
2789 | 2551 | 1275.5 | 49.32 | 24.7 | CpG islands in vertebrate genomes. | M Gardiner-Garden, M Frommer | J Mol Biol | 1987 | 3656447 | Yes |
2790 | 2551 | 1275.5 | 49.06 | 24.5 | Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis. | M Fried, D M Crothers | Nucleic Acids Res | 1981 | 6275366 | Yes |
2791 | 3826 | 1275.3 | 103.96 | 34.7 | Molecular characterization of a peripheral receptor for cannabinoids. | S Munro, K L Thomas, M Abu-Shaar | Nature | 1993 | 7689702 | Yes |
2792 | 2550 | 1275.0 | 66.18 | 33.1 | Establishment and characterization of a human histiocytic lymphoma cell line (U-937). | C Sundström, K Nilsson | Int J Cancer | 1976 | 178611 | Yes |
2793 | 1275 | 1275.0 | 45.47 | 45.5 | Experience from a multicentre stroke register: a preliminary report. | S Hatano | Bull World Health Organ | 1976 | 1088404 | Yes |
2794 | 2550 | 1275.0 | 23.67 | 11.8 | Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. | J Altman, G D Das | J Comp Neurol | 1965 | 5861717 | Yes |
2795 | 1275 | 1275.0 | 31.68 | 31.7 | Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution. | J Deisenhofer | Biochemistry | 1981 | 7236608 | Yes |
2796 | 2550 | 1275.0 | 61.21 | 30.6 | Drug delivery systems: entering the mainstream. | Theresa M Allen, Pieter R Cullis | Science | 2004 | 15031496 | Yes |
2797 | 1275 | 1275.0 | 0.0 | 0.0 | The antidiuretic hormone and the factors which determine its release. | E B Verney | Proc R Soc Lond B Biol Sci | 1947 | 18918876 | Yes |
2798 | 1275 | 1275.0 | 0.0 | 0.0 | Differential spectrophotometry of purine compounds by means of specific enzymes; studies of the enzymes of purine metabolism. | H M Kalckar | J Biol Chem | 1947 | 20285041 | Yes |
2799 | 1274 | 1274.0 | 35.92 | 35.9 | Targeting recovery: priorities of the spinal cord-injured population. | Kim D Anderson | J Neurotrauma | 2004 | 15672628 | Yes |
2800 | 1274 | 1274.0 | 40.03 | 40.0 | The Danish Register of Causes of Death. | Karin Helweg-Larsen | Scand J Public Health | 2011 | 21775346 | Yes |
2801 | 1274 | 1274.0 | 60.51 | 60.5 | The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease. | Costantino Iadecola | Neuron | 2017 | 28957666 | No |
2802 | 1273 | 1273.0 | 30.18 | 30.2 | Somatostatin and its receptor family. | Y C Patel | Front Neuroendocrinol | 1999 | 10433861 | No |
2803 | 5092 | 1273.0 | 116.66 | 29.2 | Autophagy fights disease through cellular self-digestion. | Noboru Mizushima, Beth Levine, Ana Maria Cuervo, Daniel J Klionsky | Nature | 2008 | 18305538 | No |
2804 | 1272 | 1272.0 | 29.51 | 29.5 | A likelihood approach to estimating phylogeny from discrete morphological character data. | P O Lewis | Syst Biol | 2001 | 12116640 | Yes |
2805 | 1271 | 1271.0 | 25.54 | 25.5 | Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy. | R H Schwartz | Cell | 1992 | 1335362 | No |
2806 | 3813 | 1271.0 | 112.5 | 37.5 | The functional anatomy of basal ganglia disorders. | R L Albin, A B Young, J B Penney | Trends Neurosci | 1989 | 2479133 | No |
2807 | 1271 | 1271.0 | 32.46 | 32.5 | Drug delivery and targeting. | R Langer | Nature | 1998 | 9579855 | No |
2808 | 1271 | 1271.0 | 28.97 | 29.0 | Optical microcavities. | Kerry J Vahala | Nature | 2003 | 12917698 | Yes |
2809 | 1271 | 1271.0 | 34.02 | 34.0 | Infection in solid-organ transplant recipients. | Jay A Fishman | N Engl J Med | 2007 | 18094380 | No |
2810 | 2541 | 1270.5 | 50.45 | 25.2 | A rapid, sensitive, and specific method for the determination of protein in dilute solution. | W Schaffner, C Weissmann | Anal Biochem | 1973 | 4128882 | Yes |
2811 | 2540 | 1270.0 | 76.09 | 38.0 | An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. | Sun Ho Kim, Jin Mo Chung | Pain | 1992 | 1333581 | Yes |
2812 | 1270 | 1270.0 | 32.22 | 32.2 | Rapid evolution of a protein in vitro by DNA shuffling. | W P Stemmer | Nature | 1994 | 8047147 | Yes |
2813 | 3810 | 1270.0 | 119.03 | 39.7 | MR diffusion tensor spectroscopy and imaging. | P J Basser, J Mattiello, D LeBihan | Biophys J | 1994 | 8130344 | Yes |
2814 | 1270 | 1270.0 | 31.59 | 31.6 | The effective period of preventive antibiotic action in experimental incisions and dermal lesions. | J F Burke | Surgery | 1961 | 16722001 | Yes |
2815 | 2540 | 1270.0 | 64.83 | 32.4 | Biology of incretins: GLP-1 and GIP. | Laurie L Baggio, Daniel J Drucker | Gastroenterology | 2007 | 17498508 | No |
2816 | 1270 | 1270.0 | 46.68 | 46.7 | Amyloid-β and tau: the trigger and bullet in Alzheimer disease pathogenesis. | George S Bloom | JAMA Neurol | 2014 | 24493463 | No |
2817 | 1269 | 1269.0 | 0.0 | 0.0 | A simple objective technique for measuring flexibility in thinking. | E A Berg | J Gen Psychol | 1948 | 18889466 | Yes |
2818 | 1269 | 1269.0 | 26.83 | 26.8 | Hypoxia, HIF1 and glucose metabolism in the solid tumour. | Nicholas C Denko | Nat Rev Cancer | 2008 | 19143055 | No |
2819 | 2537 | 1268.5 | 63.53 | 31.8 | Epidemiology of Parkinson's disease. | Lonneke M L de Lau, Monique M B Breteler | Lancet Neurol | 2006 | 16713924 | No |
2820 | 7610 | 1268.3 | 217.81 | 36.3 | Free radicals and antioxidants in normal physiological functions and human disease. | Marian Valko, Dieter Leibfritz, Jan Moncol, Mark T D Cronin, Milan Mazur, Joshua Telser | Int J Biochem Cell Biol | 2007 | 16978905 | No |
2821 | 1268 | 1268.0 | 62.88 | 62.9 | Assessment of chronic pain. I. Aspects of the reliability and validity of the visual analogue scale. | Anna Maria Carlsson | Pain | 1983 | 6602967 | Yes |
2822 | 2536 | 1268.0 | 51.0 | 25.5 | ERBB receptors and cancer: the complexity of targeted inhibitors. | Nancy E Hynes, Heidi A Lane | Nat Rev Cancer | 2005 | 15864276 | No |
2823 | 2535 | 1267.5 | 50.13 | 25.1 | Of mice and not men: differences between mouse and human immunology. | Javier Mestas, Christopher C W Hughes | J Immunol | 2004 | 14978070 | No |
2824 | 1267 | 1267.0 | 28.3 | 28.3 | Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration. | T A Springer | Annu Rev Physiol | 1995 | 7778885 | No |
2825 | 3801 | 1267.0 | 116.56 | 38.9 | Evaluating the public health impact of health promotion interventions: the RE-AIM framework. | R E Glasgow, T M Vogt, S M Boles | Am J Public Health | 1999 | 10474547 | No |
2826 | 2534 | 1267.0 | 44.26 | 22.1 | The DNA damage response: putting checkpoints in perspective. | B B Zhou, S J Elledge | Nature | 2000 | 11100718 | No |
2827 | 2534 | 1267.0 | 169.3 | 84.7 | An Overview of Heart Rate Variability Metrics and Norms. | Fred Shaffer, J P Ginsberg | Front Public Health | 2017 | 29034226 | No |
2828 | 2533 | 1266.5 | 13.33 | 6.7 | Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. | G J Todaro, H Green | J Cell Biol | 1963 | 13985244 | Yes |
2829 | 1266 | 1266.0 | 45.11 | 45.1 | The LMS method for constructing normalized growth standards. | T J Cole | Eur J Clin Nutr | 1990 | 2354692 | Yes |
2830 | 1266 | 1266.0 | 26.8 | 26.8 | Assortative mixing in networks. | M E J Newman | Phys Rev Lett | 2002 | 12443515 | Yes |
2831 | 2531 | 1265.5 | 56.97 | 28.5 | Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. | D A Brown, J K Rose | Cell | 1992 | 1531449 | Yes |
2832 | 1265 | 1265.0 | 26.76 | 26.8 | Molecular physiology of low-voltage-activated t-type calcium channels. | Edward Perez-Reyes | Physiol Rev | 2003 | 12506128 | No |
2833 | 2530 | 1265.0 | 77.1 | 38.5 | bold: The Barcode of Life Data System (http://www.barcodinglife.org). | Sujeevan Ratnasingham, Paul D N Hebert | Mol Ecol Notes | 2007 | 18784790 | Yes |
2834 | 3792 | 1264.0 | 186.9 | 62.3 | Assessing coping strategies: a theoretically based approach. | C S Carver, M F Scheier, J K Weintraub | J Pers Soc Psychol | 1989 | 2926629 | Yes |
2835 | 1264 | 1264.0 | 29.41 | 29.4 | Complementing the genome with an "exposome": the outstanding challenge of environmental exposure measurement in molecular epidemiology. | Christopher Paul Wild | Cancer Epidemiol Biomarkers Prev | 2005 | 16103423 | No |
2836 | 1264 | 1264.0 | 32.17 | 32.2 | The complex role of estrogens in inflammation. | Rainer H Straub | Endocr Rev | 2007 | 17640948 | No |
2837 | 2526 | 1263.0 | 102.12 | 51.1 | Rapid genetic identification and mapping of enzymatically amplified ribosomal DNA from several Cryptococcus species. | R Vilgalys, M Hester | J Bacteriol | 1990 | 2376561 | Yes |
2838 | 2526 | 1263.0 | 55.99 | 28.0 | Can the pharmaceutical industry reduce attrition rates? | Ismail Kola, John Landis | Nat Rev Drug Discov | 2004 | 15286737 | No |
2839 | 2525 | 1262.5 | 67.34 | 33.7 | Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction. | J L Weber, P E May | Am J Hum Genet | 1989 | 2916582 | Yes |
2840 | 2525 | 1262.5 | 47.19 | 23.6 | The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. | T Maehama, J E Dixon | J Biol Chem | 1998 | 9593664 | Yes |
2841 | 3787 | 1262.3 | 89.87 | 30.0 | Thresholding of statistical maps in functional neuroimaging using the false discovery rate. | Christopher R Genovese, Nicole A Lazar, Thomas Nichols | Neuroimage | 2002 | 11906227 | Yes |
2842 | 5049 | 1262.2 | 284.94 | 71.2 | Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm. | L A Papile, J Burstein, R Burstein, H Koffler | J Pediatr | 1978 | 305471 | Yes |
2843 | 5049 | 1262.2 | 105.46 | 26.4 | Interleukin-10 and the interleukin-10 receptor. | K W Moore, R de Waal Malefyt, R L Coffman, A O'Garra | Annu Rev Immunol | 2001 | 11244051 | No |
2844 | 5049 | 1262.2 | 131.65 | 32.9 | Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. | Michael J Pencina, Ralph B D'Agostino, Ralph B D'Agostino, Ramachandran S Vasan | Stat Med | 2008 | 17569110 | Yes |
2845 | 1262 | 1262.0 | 30.71 | 30.7 | Program DYNAFIT for the analysis of enzyme kinetic data: application to HIV proteinase. | P Kuzmic | Anal Biochem | 1996 | 8660575 | Yes |
2846 | 1262 | 1262.0 | 35.12 | 35.1 | The effects of stressful life events on depression. | R C Kessler | Annu Rev Psychol | 1997 | 9046559 | No |
2847 | 1262 | 1262.0 | 45.91 | 45.9 | Comfortable and maximum walking speed of adults aged 20-79 years: reference values and determinants. | R W Bohannon | Age Ageing | 1997 | 9143432 | Yes |
2848 | 2524 | 1262.0 | 48.94 | 24.5 | Proliferation, cell cycle and apoptosis in cancer. | G I Evan, K H Vousden | Nature | 2001 | 11357141 | No |
2849 | 7571 | 1261.8 | 209.69 | 34.9 | Genome engineering using the CRISPR-Cas9 system. | F Ann Ran, Patrick D Hsu, Jason Wright, Vineeta Agarwala, David A Scott, Feng Zhang | Nat Protoc | 2013 | 24157548 | Yes |
2850 | 2523 | 1261.5 | 68.93 | 34.5 | The cognitive control of emotion. | Kevin N Ochsner, James J Gross | Trends Cogn Sci | 2005 | 15866151 | No |
2851 | 1261 | 1261.0 | 33.87 | 33.9 | Signaling through phosphatidylcholine breakdown. | J H Exton | J Biol Chem | 1990 | 2104616 | No |
2852 | 1261 | 1261.0 | 14.04 | 14.0 | A restriction point for control of normal animal cell proliferation. | A B Pardee | Proc Natl Acad Sci U S A | 1974 | 4524638 | Yes |
2853 | 1261 | 1261.0 | 25.91 | 25.9 | Signal transduction via the MAP kinases: proceed at your own RSK. | J Blenis | Proc Natl Acad Sci U S A | 1993 | 8392180 | No |
2854 | 1261 | 1261.0 | 25.71 | 25.7 | Endocytosis and molecular sorting. | I Mellman | Annu Rev Cell Dev Biol | 1996 | 8970738 | No |
2855 | 1260 | 1260.0 | 30.42 | 30.4 | Short-term synaptic plasticity. | R S Zucker | Annu Rev Neurosci | 1989 | 2648947 | No |
2856 | 1260 | 1260.0 | 36.13 | 36.1 | Peptide antibiotics and their role in innate immunity. | H G Boman | Annu Rev Immunol | 1995 | 7612236 | No |
2857 | 1260 | 1260.0 | 0.0 | 0.0 | The relation of the trail making test to organic brain damage. | R M Reitan | J Consult Psychol | 1955 | 13263471 | Yes |
2858 | 1260 | 1260.0 | 0.0 | 0.0 | Intra-sexual selection in Drosophila. | A J Bateman | Heredity (Edinb) | 1948 | 18103134 | Yes |
2859 | 2519 | 1259.5 | 66.21 | 33.1 | Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. | Ajay Kumar Gupta, Mona Gupta | Biomaterials | 2005 | 15626447 | No |
2860 | 5037 | 1259.2 | 144.25 | 36.1 | Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma. | N Weidner, J P Semple, W R Welch, J Folkman | N Engl J Med | 1991 | 1701519 | Yes |
2861 | 2518 | 1259.0 | 48.39 | 24.2 | Gene silencing in cancer in association with promoter hypermethylation. | James G Herman, Stephen B Baylin | N Engl J Med | 2003 | 14627790 | No |
2862 | 2517 | 1258.5 | 73.13 | 36.6 | Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. | J I Morgan, T Curran | Annu Rev Neurosci | 1991 | 1903243 | No |
2863 | 2517 | 1258.5 | 49.82 | 24.9 | Community structure in social and biological networks. | M Girvan, M E J Newman | Proc Natl Acad Sci U S A | 2002 | 12060727 | No |
2864 | 2517 | 1258.5 | 53.61 | 26.8 | Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. | Eugenia E Calle, Rudolf Kaaks | Nat Rev Cancer | 2004 | 15286738 | No |
2865 | 1258 | 1258.0 | 25.7 | 25.7 | SETOR: hardware-lighted three-dimensional solid model representations of macromolecules. | S V Evans | J Mol Graph | 1993 | 8347566 | Yes |
2866 | 1258 | 1258.0 | 44.58 | 44.6 | Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes. | M A Lemp | CLAO J | 1995 | 8565190 | No |
2867 | 2516 | 1258.0 | 66.95 | 33.5 | Increasing incidence of thyroid cancer in the United States, 1973-2002. | Louise Davies, H Gilbert Welch | JAMA | 2006 | 16684987 | Yes |
2868 | 3773 | 1257.7 | 224.06 | 74.7 | Production, use, and fate of all plastics ever made. | Roland Geyer, Jenna R Jambeck, Kara Lavender Law | Sci Adv | 2017 | 28776036 | Yes |
2869 | 1257 | 1257.0 | 70.49 | 70.5 | The diagnosis of ischaemic heart pain and intermittent claudication in field surveys. | G A Rose | Bull World Health Organ | 1962 | 13974778 | Yes |
2870 | 1257 | 1257.0 | 30.37 | 30.4 | Electrochemiluminescence (ECL). | Mark M Richter | Chem Rev | 2004 | 15186186 | No |
2871 | 1257 | 1257.0 | 31.56 | 31.6 | Functionalized acenes and heteroacenes for organic electronics. | John E Anthony | Chem Rev | 2006 | 17165682 | Yes |
2872 | 1257 | 1257.0 | 38.53 | 38.5 | Clinical practice. Endometriosis. | Linda C Giudice | N Engl J Med | 2010 | 20573927 | No |
2873 | 10053 | 1256.6 | 255.66 | 32.0 | A method and server for predicting damaging missense mutations. | Ivan A Adzhubei, Steffen Schmidt, Leonid Peshkin, Vasily E Ramensky, Anna Gerasimova, Peer Bork, Alexey S Kondrashov, Shamil R Sunyaev | Nat Methods | 2010 | 20354512 | Yes |
2874 | 2513 | 1256.5 | 61.67 | 30.8 | Pharmacology and functions of metabotropic glutamate receptors. | P J Conn, J P Pin | Annu Rev Pharmacol Toxicol | 1997 | 9131252 | No |
2875 | 1256 | 1256.0 | 83.09 | 83.1 | The problem of rigor in qualitative research. | M Sandelowski | ANS Adv Nurs Sci | 1986 | 3083765 | Yes |
2876 | 1256 | 1256.0 | 42.87 | 42.9 | Inhibition and facilitation of nucleic acid amplification. | I G Wilson | Appl Environ Microbiol | 1997 | 9327537 | No |
2877 | 1256 | 1256.0 | 32.13 | 32.1 | Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome: a summary of the evidence. | Earl S Ford | Diabetes Care | 2005 | 15983333 | No |
2878 | 1256 | 1256.0 | 25.94 | 25.9 | The roles of intracellular protein-degradation pathways in neurodegeneration. | David C Rubinsztein | Nature | 2006 | 17051204 | No |
2879 | 1256 | 1256.0 | 39.27 | 39.3 | Tumor delivery of macromolecular drugs based on the EPR effect. | Vladimir Torchilin | Adv Drug Deliv Rev | 2011 | 20304019 | No |
2880 | 2512 | 1256.0 | 64.35 | 32.2 | The ubiquitin code. | David Komander, Michael Rape | Annu Rev Biochem | 2012 | 22524316 | No |
2881 | 1256 | 1256.0 | 68.22 | 68.2 | Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features and Rome IV. | Douglas A Drossman | Gastroenterology | 2016 | 27144617 | Yes |
2882 | 2511 | 1255.5 | 60.28 | 30.1 | Predictive coding in the visual cortex: a functional interpretation of some extra-classical receptive-field effects. | R P Rao, D H Ballard | Nat Neurosci | 1999 | 10195184 | Yes |
2883 | 3766 | 1255.3 | 112.19 | 37.4 | Oxidants, antioxidants, and the degenerative diseases of aging. | B N Ames, M K Shigenaga, T M Hagen | Proc Natl Acad Sci U S A | 1993 | 8367443 | No |
2884 | 7531 | 1255.2 | 280.9 | 46.8 | Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science. | Laura J Damschroder, David C Aron, Rosalind E Keith, Susan R Kirsh, Jeffery A Alexander, Julie C Lowery | Implement Sci | 2009 | 19664226 | Yes |
2885 | 1255 | 1255.0 | 30.48 | 30.5 | Primate anterior cingulate cortex: where motor control, drive and cognition interface. | T Paus | Nat Rev Neurosci | 2001 | 11389475 | No |
2886 | 1255 | 1255.0 | 41.53 | 41.5 | Physiological implications of hydrogen sulfide: a whiff exploration that blossomed. | Rui Wang | Physiol Rev | 2012 | 22535897 | No |
2887 | 13804 | 1254.9 | 326.98 | 29.7 | New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. | P Therasse, S G Arbuck, E A Eisenhauer, J Wanders, R S Kaplan, L Rubinstein, J Verweij, M Van Glabbeke, A T van Oosterom, M C Christian, S G Gwyther | J Natl Cancer Inst | 2000 | 10655437 | No |
2888 | 1254 | 1254.0 | 31.48 | 31.5 | Apoptosis. | J J Cohen | Immunol Today | 1993 | 8466628 | No |
2889 | 1254 | 1254.0 | 27.06 | 27.1 | S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles. | R Donato | Int J Biochem Cell Biol | 2001 | 11390274 | No |
2890 | 1254 | 1254.0 | 27.76 | 27.8 | Neurobiology of Pavlovian fear conditioning. | S Maren | Annu Rev Neurosci | 2001 | 11520922 | No |
2891 | 3762 | 1254.0 | 88.02 | 29.3 | Global and societal implications of the diabetes epidemic. | P Zimmet, K G Alberti, J Shaw | Nature | 2001 | 11742409 | No |
2892 | 1254 | 1254.0 | 38.63 | 38.6 | Sensorimotor integration in human postural control. | R J Peterka | J Neurophysiol | 2002 | 12205132 | Yes |
2893 | 2508 | 1254.0 | 56.05 | 28.0 | Cellular processing of platinum anticancer drugs. | Dong Wang, Stephen J Lippard | Nat Rev Drug Discov | 2005 | 15789122 | No |
2894 | 1253 | 1253.0 | 33.78 | 33.8 | Current source-density method and application in cat cerebral cortex: investigation of evoked potentials and EEG phenomena. | U Mitzdorf | Physiol Rev | 1985 | 3880898 | No |
2895 | 1253 | 1253.0 | 31.92 | 31.9 | Strategy and tactics in protein chemistry. | B S Hartley | Biochem J | 1970 | 4923920 | No |
2896 | 1253 | 1253.0 | 42.19 | 42.2 | Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells. | R Lotan | Biochim Biophys Acta | 1980 | 6989400 | No |
2897 | 1253 | 1253.0 | 75.4 | 75.4 | Non-alcoholic fatty liver disease - A global public health perspective. | Zobair M Younossi | J Hepatol | 2019 | 30414863 | No |
2898 | 3758 | 1252.7 | 78.77 | 26.3 | Computer visualization of three-dimensional image data using IMOD. | J R Kremer, D N Mastronarde, J R McIntosh | J Struct Biol | 1996 | 8742726 | Yes |
2899 | 3757 | 1252.3 | 103.76 | 34.6 | Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. | Günter Oberdörster, Eva Oberdörster, Jan Oberdörster | Environ Health Perspect | 2005 | 16002369 | No |
2900 | 1252 | 1252.0 | 52.77 | 52.8 | A cochlear frequency-position function for several species--29 years later. | D D Greenwood | J Acoust Soc Am | 1990 | 2373794 | Yes |
2901 | 1252 | 1252.0 | 34.52 | 34.5 | Tumor angiogenesis. | J Folkman | Adv Cancer Res | 1985 | 2581424 | No |
2902 | 1252 | 1252.0 | 24.76 | 24.8 | Searching for genetic determinants in the new millennium. | N J Risch | Nature | 2000 | 10866211 | No |
2903 | 1252 | 1252.0 | 49.89 | 49.9 | The variable nature of cognitive control: a dual mechanisms framework. | Todd S Braver | Trends Cogn Sci | 2012 | 22245618 | Yes |
2904 | 5007 | 1251.8 | 159.6 | 39.9 | Validation of a combined comorbidity index. | M Charlson, T P Szatrowski, J Peterson, J Gold | J Clin Epidemiol | 1994 | 7722560 | Yes |
2905 | 2503 | 1251.5 | 57.83 | 28.9 | DNA sequence analysis with a modified bacteriophage T7 DNA polymerase. | S Tabor, C C Richardson | Proc Natl Acad Sci U S A | 1987 | 3474623 | Yes |
2906 | 1251 | 1251.0 | 29.32 | 29.3 | Reactive oxygen radicals in signaling and damage in the ischemic brain. | P H Chan | J Cereb Blood Flow Metab | 2001 | 11149664 | No |
2907 | 1250 | 1250.0 | 57.75 | 57.8 | A cognitive approach to panic. | D M Clark | Behav Res Ther | 1986 | 3741311 | Yes |
2908 | 1250 | 1250.0 | 30.59 | 30.6 | Automatic quantitation of localized in vivo 1H spectra with LCModel. | S W Provencher | NMR Biomed | 2001 | 11410943 | Yes |
2909 | 2500 | 1250.0 | 61.41 | 30.7 | Hydrogels for tissue engineering. | K Y Lee, D J Mooney | Chem Rev | 2001 | 11710233 | No |
2910 | 1250 | 1250.0 | 45.96 | 46.0 | The evolving concept of health literacy. | Don Nutbeam | Soc Sci Med | 2008 | 18952344 | Yes |
2911 | 2499 | 1249.5 | 68.79 | 34.4 | Nitric oxide synthases: roles, tolls, and controls. | C Nathan, Q W Xie | Cell | 1994 | 7522969 | No |
2912 | 2499 | 1249.5 | 64.47 | 32.2 | Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. | Barry J Everitt, Trevor W Robbins | Nat Neurosci | 2005 | 16251991 | No |
2913 | 1249 | 1249.0 | 33.17 | 33.2 | Akaike's information criterion in generalized estimating equations. | W Pan | Biometrics | 2001 | 11252586 | Yes |
2914 | 2495 | 1247.5 | 62.32 | 31.2 | Nanostructures in biodiagnostics. | Nathaniel L Rosi, Chad A Mirkin | Chem Rev | 2005 | 15826019 | No |
2915 | 1247 | 1247.0 | 42.83 | 42.8 | Estimation of the number of nucleotide substitutions when there are strong transition-transversion and G+C-content biases. | K Tamura | Mol Biol Evol | 1992 | 1630306 | Yes |
2916 | 1247 | 1247.0 | 20.57 | 20.6 | Antigen receptor tail clue. | M Reth | Nature | 1989 | 2927501 | Yes |
2917 | 1247 | 1247.0 | 24.52 | 24.5 | Structure and function of intercellular junctions. | L A Staehelin | Int Rev Cytol | 1974 | 4611943 | No |
2918 | 1247 | 1247.0 | 36.1 | 36.1 | Invasive aspergillosis. | D W Denning | Clin Infect Dis | 1998 | 9564455 | No |
2919 | 2494 | 1247.0 | 43.77 | 21.9 | Stats: transcriptional control and biological impact. | David E Levy, J E Darnell | Nat Rev Mol Cell Biol | 2002 | 12209125 | No |
2920 | 2493 | 1246.5 | 91.12 | 45.6 | The stunned myocardium: prolonged, postischemic ventricular dysfunction. | E Braunwald, R A Kloner | Circulation | 1982 | 6754130 | No |
2921 | 1246 | 1246.0 | 30.12 | 30.1 | Measurement of feelings using visual analogue scales. | R C Aitken | Proc R Soc Med | 1969 | 4899510 | No |
2922 | 3737 | 1245.7 | 117.26 | 39.1 | Qualitative research in health care. Analysing qualitative data. | C Pope, S Ziebland, N Mays | BMJ | 2000 | 10625273 | No |
2923 | 1245 | 1245.0 | 64.79 | 64.8 | Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method. | K Satoh | Clin Chim Acta | 1978 | 719890 | Yes |
2924 | 1245 | 1245.0 | 22.69 | 22.7 | Neuron-glia relationship during granule cell migration in developing cerebellar cortex. A Golgi and electronmicroscopic study in Macacus Rhesus. | P Rakic | J Comp Neurol | 1971 | 4101340 | Yes |
2925 | 1245 | 1245.0 | 24.74 | 24.7 | STATs: signal transducers and activators of transcription. | J N Ihle | Cell | 1996 | 8608586 | No |
2926 | 1245 | 1245.0 | 35.46 | 35.5 | Varieties of impulsivity. | J L Evenden | Psychopharmacology (Berl) | 1999 | 10550486 | No |
2927 | 1245 | 1245.0 | 0.0 | 0.0 | A modification of receptor theory. | R P Stephenson | Br J Pharmacol Chemother | 1956 | 13383117 | Yes |
2928 | 1245 | 1245.0 | 52.67 | 52.7 | Environmentally induced oxidative stress in aquatic animals. | Volodymyr I Lushchak | Aquat Toxicol | 2011 | 21074869 | No |
2929 | 1245 | 1245.0 | 55.36 | 55.4 | Salience processing and insular cortical function and dysfunction. | Lucina Q Uddin | Nat Rev Neurosci | 2015 | 25406711 | No |
2930 | 2488 | 1244.0 | 47.94 | 24.0 | Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. | C W Greider, E H Blackburn | Cell | 1985 | 3907856 | Yes |
2931 | 1244 | 1244.0 | 27.53 | 27.5 | Life, death, and the pursuit of apoptosis. | E White | Genes Dev | 1996 | 8557188 | No |
2932 | 1244 | 1244.0 | 29.93 | 29.9 | Plant salt tolerance. | J K Zhu | Trends Plant Sci | 2001 | 11173290 | Yes |
2933 | 3731 | 1243.7 | 115.99 | 38.7 | Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS. | B K Matuszewski, M L Constanzer, C M Chavez-Eng | Anal Chem | 2003 | 12964746 | Yes |
2934 | 2487 | 1243.5 | 63.06 | 31.5 | Genetic dissection of complex traits. | E S Lander, N J Schork | Science | 1994 | 8091226 | No |
2935 | 2486 | 1243.0 | 76.72 | 38.4 | Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. | J E Hixson, D T Vernier | J Lipid Res | 1990 | 2341813 | Yes |
2936 | 2486 | 1243.0 | 102.62 | 51.3 | Reading senseless sentences: brain potentials reflect semantic incongruity. | M Kutas, S A Hillyard | Science | 1980 | 7350657 | Yes |
2937 | 1243 | 1243.0 | 32.56 | 32.6 | The lipocalin protein family: structure and function. | D R Flower | Biochem J | 1996 | 8761444 | No |
2938 | 1243 | 1243.0 | 0.0 | 0.0 | Sequential tests for the detection of linkage. | N E Morton | Am J Hum Genet | 1955 | 13258560 | Yes |
2939 | 1243 | 1243.0 | 37.5 | 37.5 | Delirium in older persons. | Sharon K Inouye | N Engl J Med | 2006 | 16540616 | No |
2940 | 1243 | 1243.0 | 28.91 | 28.9 | Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis. | R Balfour Sartor | Nat Clin Pract Gastroenterol Hepatol | 2006 | 16819502 | No |
2941 | 4968 | 1242.0 | 136.56 | 34.1 | AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. | Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan | Nat Cell Biol | 2011 | 21258367 | Yes |
2942 | 3724 | 1241.3 | 184.3 | 61.4 | Hepatocellular carcinoma. | Alejandro Forner, María Reig, Jordi Bruix | Lancet | 2018 | 29307467 | No |
2943 | 1241 | 1241.0 | 42.01 | 42.0 | How is the level of free arachidonic acid controlled in mammalian cells? | R F Irvine | Biochem J | 1982 | 6810878 | No |
2944 | 2482 | 1241.0 | 57.39 | 28.7 | Peroxisome proliferator-activated receptors: nuclear control of metabolism. | B Desvergne, W Wahli | Endocr Rev | 1999 | 10529898 | No |
2945 | 1240 | 1240.0 | 32.51 | 32.5 | Low density lipoprotein oxidation and its pathobiological significance. | D Steinberg | J Biol Chem | 1997 | 9261091 | No |
2946 | 2480 | 1240.0 | 62.81 | 31.4 | Hydrogels for tissue engineering: scaffold design variables and applications. | Jeanie L Drury, David J Mooney | Biomaterials | 2003 | 12922147 | No |
2947 | 2480 | 1240.0 | 65.91 | 33.0 | Meeting of minds: the medial frontal cortex and social cognition. | David M Amodio, Chris D Frith | Nat Rev Neurosci | 2006 | 16552413 | No |
2948 | 1240 | 1240.0 | 47.75 | 47.8 | The biology and function of exosomes in cancer. | Raghu Kalluri | J Clin Invest | 2016 | 27035812 | No |
2949 | 2478 | 1239.0 | 48.36 | 24.2 | Checkpoints: controls that ensure the order of cell cycle events. | L H Hartwell, T A Weinert | Science | 1989 | 2683079 | No |
2950 | 2478 | 1239.0 | 61.31 | 30.7 | Molecular mechanisms of action of steroid/thyroid receptor superfamily members. | M J Tsai, B W O'Malley | Annu Rev Biochem | 1994 | 7979245 | No |
2951 | 2477 | 1238.5 | 53.16 | 26.6 | The role of polyamines in the neutralization of bacteriophage deoxyribonucleic acid. | B N Ames, D T Dubin | J Biol Chem | 1960 | 13793161 | Yes |
2952 | 1238 | 1238.0 | 24.61 | 24.6 | Evo-devo and an expanding evolutionary synthesis: a genetic theory of morphological evolution. | Sean B Carroll | Cell | 2008 | 18614008 | Yes |
2953 | 6185 | 1237.0 | 303.64 | 60.7 | Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. | N Bellamy, W W Buchanan, C H Goldsmith, J Campbell, L W Stitt | J Rheumatol | 1988 | 3068365 | Yes |
2954 | 1237 | 1237.0 | 49.64 | 49.6 | Bone "mass" and the "mechanostat": a proposal. | H M Frost | Anat Rec | 1987 | 3688455 | Yes |
2955 | 1237 | 1237.0 | 36.56 | 36.6 | Calcium channel modulation by neurotransmitters, enzymes and drugs. | H Reuter | Nature | 1983 | 6131381 | No |
2956 | 1237 | 1237.0 | 27.41 | 27.4 | Brain tumors. | L M DeAngelis | N Engl J Med | 2001 | 11150363 | No |
2957 | 1236 | 1236.0 | 24.28 | 24.3 | Cytokines induce the development of functionally heterogeneous T helper cell subsets. | A O'Garra | Immunity | 1998 | 9529145 | No |
2958 | 1236 | 1236.0 | 33.79 | 33.8 | The stress response to trauma and surgery. | J P Desborough | Br J Anaesth | 2000 | 10927999 | No |
2959 | 1235 | 1235.0 | 38.01 | 38.0 | Risk and maintenance factors for eating pathology: a meta-analytic review. | Eric Stice | Psychol Bull | 2002 | 12206196 | No |
2960 | 11107 | 1234.1 | 281.58 | 31.3 | MolProbity: all-atom structure validation for macromolecular crystallography. | Vincent B Chen, W Bryan Arendall, Jeffrey J Headd, Daniel A Keedy, Robert M Immormino, Gary J Kapral, Laura W Murray, Jane S Richardson, David C Richardson | Acta Crystallogr D Biol Crystallogr | 2010 | 20057044 | Yes |
2961 | 1234 | 1234.0 | 21.49 | 21.5 | Mutation selection and the natural history of cancer. | J Cairns | Nature | 1975 | 1143315 | Yes |
2962 | 1234 | 1234.0 | 38.79 | 38.8 | Antioxidants in human health and disease. | B Halliwell | Annu Rev Nutr | 1996 | 8839918 | No |
2963 | 2468 | 1234.0 | 64.82 | 32.4 | A review of central 5-HT receptors and their function. | N M Barnes, T Sharp | Neuropharmacology | 1999 | 10462127 | No |
2964 | 1234 | 1234.0 | 26.28 | 26.3 | Microglia as a source and target of cytokines. | Uwe-Karsten Hanisch | Glia | 2002 | 12379902 | No |
2965 | 2468 | 1234.0 | 72.75 | 36.4 | Inflammatory mechanisms in obesity. | Margaret F Gregor, Gökhan S Hotamisligil | Annu Rev Immunol | 2011 | 21219177 | No |
2966 | 1234 | 1234.0 | 58.64 | 58.6 | Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review. | Dariush Mozaffarian | Circulation | 2016 | 26746178 | No |
2967 | 1233 | 1233.0 | 25.24 | 25.2 | Fibrotic disease and the T(H)1/T(H)2 paradigm. | Thomas A Wynn | Nat Rev Immunol | 2004 | 15286725 | No |
2968 | 1233 | 1233.0 | 27.7 | 27.7 | Production of recombinant protein therapeutics in cultivated mammalian cells. | Florian M Wurm | Nat Biotechnol | 2004 | 15529164 | No |
2969 | 2466 | 1233.0 | 57.94 | 29.0 | Principles of bioactive lipid signalling: lessons from sphingolipids. | Yusuf A Hannun, Lina M Obeid | Nat Rev Mol Cell Biol | 2008 | 18216770 | No |
2970 | 4930 | 1232.5 | 153.32 | 38.3 | Epidemiology and causes of preterm birth. | Robert L Goldenberg, Jennifer F Culhane, Jay D Iams, Roberto Romero | Lancet | 2008 | 18177778 | No |
2971 | 2464 | 1232.0 | 68.22 | 34.1 | Ageing and Parkinson's disease: substantia nigra regional selectivity. | J M Fearnley, A J Lees | Brain | 1991 | 1933245 | Yes |
2972 | 1232 | 1232.0 | 22.21 | 22.2 | Kinesin and dynein superfamily proteins and the mechanism of organelle transport. | N Hirokawa | Science | 1998 | 9438838 | No |
2973 | 2464 | 1232.0 | 62.96 | 31.5 | Humans integrate visual and haptic information in a statistically optimal fashion. | Marc O Ernst, Martin S Banks | Nature | 2002 | 11807554 | Yes |
2974 | 2464 | 1232.0 | 211.39 | 105.7 | The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. | Hussin A Rothan, Siddappa N Byrareddy | J Autoimmun | 2020 | 32113704 | No |
2975 | 2463 | 1231.5 | 67.51 | 33.8 | New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. | Jonathan B Baell, Georgina A Holloway | J Med Chem | 2010 | 20131845 | Yes |
2976 | 2462 | 1231.0 | 65.81 | 32.9 | Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications. | M A Pfeffer, E Braunwald | Circulation | 1990 | 2138525 | No |
2977 | 1231 | 1231.0 | 55.61 | 55.6 | Continuous improvement as an ideal in health care. | D M Berwick | N Engl J Med | 1989 | 2909878 | Yes |
2978 | 1231 | 1231.0 | 35.26 | 35.3 | The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin. | R G Pertwee | Br J Pharmacol | 2008 | 17828291 | No |
2979 | 6154 | 1230.8 | 192.59 | 38.5 | Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. | J S Beckman, T W Beckman, J Chen, P A Marshall, B A Freeman | Proc Natl Acad Sci U S A | 1990 | 2154753 | Yes |
2980 | 6153 | 1230.6 | 288.67 | 57.7 | CheckM: assessing the quality of microbial genomes recovered from isolates, single cells, and metagenomes. | Donovan H Parks, Michael Imelfort, Connor T Skennerton, Philip Hugenholtz, Gene W Tyson | Genome Res | 2015 | 25977477 | Yes |
2981 | 2461 | 1230.5 | 39.49 | 19.7 | A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. | D Tautz, C Pfeifle | Chromosoma | 1989 | 2476281 | Yes |
2982 | 1230 | 1230.0 | 22.54 | 22.5 | Histone-deacetylase inhibitors: novel drugs for the treatment of cancer. | Ricky W Johnstone | Nat Rev Drug Discov | 2002 | 12120280 | No |
2983 | 1229 | 1229.0 | 33.62 | 33.6 | Water as an active constituent in cell biology. | Philip Ball | Chem Rev | 2008 | 18095715 | No |
2984 | 1228 | 1228.0 | 44.24 | 44.2 | Transduction of psychosocial stress into the neurobiology of recurrent affective disorder. | R M Post | Am J Psychiatry | 1992 | 1353322 | No |
2985 | 1228 | 1228.0 | 24.34 | 24.3 | Basement membranes: structure, assembly and role in tumour angiogenesis. | Raghu Kalluri | Nat Rev Cancer | 2003 | 12778132 | No |
2986 | 1228 | 1228.0 | 34.94 | 34.9 | High prevalence of vitamin D inadequacy and implications for health. | Michael F Holick | Mayo Clin Proc | 2006 | 16529140 | No |
2987 | 3682 | 1227.3 | 86.4 | 28.8 | Prediction of total genetic value using genome-wide dense marker maps. | T H Meuwissen, B J Hayes, M E Goddard | Genetics | 2001 | 11290733 | Yes |
2988 | 1227 | 1227.0 | 24.02 | 24.0 | Up on the tightrope: natural killer cell activation and inhibition. | Lewis L Lanier | Nat Immunol | 2008 | 18425106 | No |
2989 | 1226 | 1226.0 | 33.82 | 33.8 | Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections. | F Hefti | J Neurosci | 1986 | 3746405 | Yes |
2990 | 1226 | 1226.0 | 21.16 | 21.2 | Biochemical adaptations in muscle. Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle. | J O Holloszy | J Biol Chem | 1967 | 4290225 | Yes |
2991 | 1226 | 1226.0 | 13.88 | 13.9 | Central dogma of molecular biology. | F Crick | Nature | 1970 | 4913914 | No |
2992 | 1226 | 1226.0 | 20.18 | 20.2 | Mitotic kinases as regulators of cell division and its checkpoints. | E A Nigg | Nat Rev Mol Cell Biol | 2001 | 11413462 | No |
2993 | 2452 | 1226.0 | 86.51 | 43.3 | Severe sepsis and septic shock. | Derek C Angus, Tom van der Poll | N Engl J Med | 2013 | 23984731 | No |
2994 | 12254 | 1225.4 | 474.38 | 47.4 | MrBayes 3.2: efficient Bayesian phylogenetic inference and model choice across a large model space. | Fredrik Ronquist, Maxim Teslenko, Paul van der Mark, Daniel L Ayres, Aaron Darling, Sebastian Höhna, Bret Larget, Liang Liu, Marc A Suchard, John P Huelsenbeck | Syst Biol | 2012 | 22357727 | Yes |
2995 | 2450 | 1225.0 | 53.9 | 26.9 | Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange. | G K McMaster, G G Carmichael | Proc Natl Acad Sci U S A | 1977 | 73185 | Yes |
2996 | 1225 | 1225.0 | 32.02 | 32.0 | Preparation of rat liver cells. 3. Enzymatic requirements for tissue dispersion. | P O Seglen | Exp Cell Res | 1973 | 4358115 | Yes |
2997 | 1225 | 1225.0 | 15.1 | 15.1 | Cumulative dose-response curves. II. Technique for the making of dose-response curves in isolated organs and the evaluation of drug parameters. | J M Van Rossum | Arch Int Pharmacodyn Ther | 1963 | 13996119 | Yes |
2998 | 1225 | 1225.0 | 27.85 | 27.9 | Oxidative stress in neurodegeneration: cause or consequence? | Julie K Andersen | Nat Med | 2004 | 15298006 | No |
2999 | 2448 | 1224.0 | 75.0 | 37.5 | A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data. | A Ennaceur, J Delacour | Behav Brain Res | 1988 | 3228475 | Yes |
3000 | 1224 | 1224.0 | 37.75 | 37.8 | Socioeconomic status and obesity. | Lindsay McLaren | Epidemiol Rev | 2007 | 17478442 | No |
3001 | 1224 | 1224.0 | 28.99 | 29.0 | Targeting DNA topoisomerase II in cancer chemotherapy. | John L Nitiss | Nat Rev Cancer | 2009 | 19377506 | No |
3002 | 1224 | 1224.0 | 47.03 | 47.0 | A review and synthesis of the first 20 years of PET and fMRI studies of heard speech, spoken language and reading. | Cathy J Price | Neuroimage | 2012 | 22584224 | No |
3003 | 1224 | 1224.0 | 44.69 | 44.7 | The biogenesis and emerging roles of circular RNAs. | Ling-Ling Chen | Nat Rev Mol Cell Biol | 2016 | 26908011 | Yes |
3004 | 4894 | 1223.5 | 137.65 | 34.4 | Biological identifications through DNA barcodes. | Paul D N Hebert, Alina Cywinska, Shelley L Ball, Jeremy R deWaard | Proc Biol Sci | 2003 | 12614582 | Yes |
3005 | 4893 | 1223.2 | 128.85 | 32.2 | Organometal halide perovskites as visible-light sensitizers for photovoltaic cells. | Akihiro Kojima, Kenjiro Teshima, Yasuo Shirai, Tsutomu Miyasaka | J Am Chem Soc | 2009 | 19366264 | Yes |
3006 | 1223 | 1223.0 | 25.77 | 25.8 | Antigen-presenting function of the macrophage. | E R Unanue | Annu Rev Immunol | 1984 | 6242349 | No |
3007 | 1223 | 1223.0 | 37.62 | 37.6 | Peritonectomy procedures. | P H Sugarbaker | Ann Surg | 1995 | 7826158 | Yes |
3008 | 1223 | 1223.0 | 26.15 | 26.1 | Nuclear factor-kappaB: the enemy within. | Bharat B Aggarwal | Cancer Cell | 2004 | 15380510 | No |
3009 | 1223 | 1223.0 | 0.0 | 0.0 | Immunity to homologous grafted skin; the fate of skin homografts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye. | P B Medawar | Br J Exp Pathol | 1948 | 18865105 | Yes |
3010 | 1223 | 1223.0 | 29.94 | 29.9 | Molecular genetics of colorectal cancer. | Eric R Fearon | Annu Rev Pathol | 2011 | 21090969 | No |
3011 | 1222 | 1222.0 | 22.25 | 22.2 | Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture. | H E Ruley | Nature | 1983 | 6308473 | Yes |
3012 | 1222 | 1222.0 | 25.21 | 25.2 | MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. | R N Germain | Cell | 1994 | 8293464 | No |
3013 | 1222 | 1222.0 | 30.84 | 30.8 | Neural systems for recognizing emotion. | Ralph Adolphs | Curr Opin Neurobiol | 2002 | 12015233 | No |
3014 | 3666 | 1222.0 | 246.88 | 82.3 | Sample Size in Qualitative Interview Studies: Guided by Information Power. | Kirsti Malterud, Volkert Dirk Siersma, Ann Dorrit Guassora | Qual Health Res | 2016 | 26613970 | Yes |
3015 | 4887 | 1221.8 | 113.24 | 28.3 | Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. | G L Wang, B H Jiang, E A Rue, G L Semenza | Proc Natl Acad Sci U S A | 1995 | 7539918 | Yes |
3016 | 1221 | 1221.0 | 62.77 | 62.8 | Rating scales to assess depression in school-aged children. | M Kovacs | Acta Paedopsychiatr | 1981 | 7025571 | Yes |
3017 | 1221 | 1221.0 | 45.21 | 45.2 | Myeloid-Derived Suppressor Cells. | Dmitry I Gabrilovich | Cancer Immunol Res | 2017 | 28052991 | No |
3018 | 4882 | 1220.5 | 235.86 | 59.0 | NF-κB signaling in inflammation. | Ting Liu, Lingyun Zhang, Donghyun Joo, Shao-Cong Sun | Signal Transduct Target Ther | 2017 | 29158945 | Yes |
3019 | 1220 | 1220.0 | 44.82 | 44.8 | The P300 wave of the human event-related potential. | T W Picton | J Clin Neurophysiol | 1992 | 1464675 | No |
3020 | 1220 | 1220.0 | 28.6 | 28.6 | Growth factors and cancer. | S A Aaronson | Science | 1991 | 1659742 | No |
3021 | 1220 | 1220.0 | 26.46 | 26.5 | An overview of epithelio-mesenchymal transformation. | E D Hay | Acta Anat (Basel) | 1995 | 8714286 | No |
3022 | 1220 | 1220.0 | 33.37 | 33.4 | Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective. | Antoine Bechara | Nat Neurosci | 2005 | 16251988 | No |
3023 | 1220 | 1220.0 | 43.5 | 43.5 | Postural orientation and equilibrium: what do we need to know about neural control of balance to prevent falls? | Fay B Horak | Age Ageing | 2006 | 16926210 | No |
3024 | 1220 | 1220.0 | 24.16 | 24.2 | Protein tyrosine phosphatases: from genes, to function, to disease. | Nicholas K Tonks | Nat Rev Mol Cell Biol | 2006 | 17057753 | No |
3025 | 1220 | 1220.0 | 26.2 | 26.2 | Simple model of spiking neurons. | E M Izhikevich | IEEE Trans Neural Netw | 2003 | 18244602 | Yes |
3026 | 1219 | 1219.0 | 26.56 | 26.6 | Heterotrimeric G proteins: organizers of transmembrane signals. | E J Neer | Cell | 1995 | 7834744 | No |
3027 | 1219 | 1219.0 | 30.4 | 30.4 | Endothelial-leukocyte adhesion molecules. | M P Bevilacqua | Annu Rev Immunol | 1993 | 8476577 | No |
3028 | 1219 | 1219.0 | 25.88 | 25.9 | Dendritic cells: unique leukocyte populations which control the primary immune response. | D N Hart | Blood | 1997 | 9345009 | No |
3029 | 1219 | 1219.0 | 0.0 | 0.0 | A production of amino acids under possible primitive earth conditions. | S L Miller | Science | 1953 | 13056598 | Yes |
3030 | 1219 | 1219.0 | 30.6 | 30.6 | Polymer conjugates as anticancer nanomedicines. | Ruth Duncan | Nat Rev Cancer | 2006 | 16900224 | No |
3031 | 1219 | 1219.0 | 31.61 | 31.6 | Thermo- and pH-responsive polymers in drug delivery. | Dirk Schmaljohann | Adv Drug Deliv Rev | 2006 | 17125884 | No |
3032 | 3655 | 1218.3 | 90.9 | 30.3 | Use and abuse of HOMA modeling. | Tara M Wallace, Jonathan C Levy, David R Matthews | Diabetes Care | 2004 | 15161807 | No |
3033 | 2436 | 1218.0 | 50.54 | 25.3 | Sequence logos: a new way to display consensus sequences. | T D Schneider, R M Stephens | Nucleic Acids Res | 1990 | 2172928 | Yes |
3034 | 1218 | 1218.0 | 23.65 | 23.6 | A microRNA as a translational repressor of APETALA2 in Arabidopsis flower development. | Xuemei Chen | Science | 2004 | 12893888 | Yes |
3035 | 2435 | 1217.5 | 47.8 | 23.9 | Molecular chaperones in the cytosol: from nascent chain to folded protein. | F Ulrich Hartl, Manajit Hayer-Hartl | Science | 2002 | 11884745 | No |
3036 | 3652 | 1217.3 | 61.16 | 20.4 | A system for stable expression of short interfering RNAs in mammalian cells. | Thijn R Brummelkamp, René Bernards, Reuven Agami | Science | 2002 | 11910072 | Yes |
3037 | 1217 | 1217.0 | 35.12 | 35.1 | A human model of gastric carcinogenesis. | P Correa | Cancer Res | 1988 | 3288329 | No |
3038 | 1217 | 1217.0 | 39.7 | 39.7 | Starting at the beginning: an introduction to coefficient alpha and internal consistency. | David L Streiner | J Pers Assess | 2003 | 12584072 | Yes |
3039 | 1217 | 1217.0 | 60.17 | 60.2 | Patient reported outcome measures could help transform healthcare. | Nick Black | BMJ | 2013 | 23358487 | Yes |
3040 | 12169 | 1216.9 | 436.99 | 43.7 | The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. | Alessandro Liberati, Douglas G Altman, Jennifer Tetzlaff, Cynthia Mulrow, Peter C Gøtzsche, John P A Ioannidis, Mike Clarke, P J Devereaux, Jos Kleijnen, David Moher | BMJ | 2009 | 19622552 | No |
3041 | 2433 | 1216.5 | 26.0 | 13.0 | The Aggregation Of Blood Platelets. | G V Born, M J Cross | J Physiol | 1963 | 14056485 | Yes |
3042 | 1216 | 1216.0 | 45.6 | 45.6 | A cognitive model of drug urges and drug-use behavior: role of automatic and nonautomatic processes. | S T Tiffany | Psychol Rev | 1990 | 2186423 | No |
3043 | 1216 | 1216.0 | 42.06 | 42.1 | Hydrophilic-interaction chromatography for the separation of peptides, nucleic acids and other polar compounds. | A J Alpert | J Chromatogr | 1990 | 2324207 | Yes |
3044 | 1216 | 1216.0 | 34.28 | 34.3 | What is synergy? | M C Berenbaum | Pharmacol Rev | 1989 | 2692037 | No |
3045 | 1216 | 1216.0 | 44.55 | 44.5 | Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment. | S H Safe | Crit Rev Toxicol | 1994 | 8037844 | No |
3046 | 2431 | 1215.5 | 70.59 | 35.3 | A fast, lock-free approach for efficient parallel counting of occurrences of k-mers. | Guillaume Marçais, Carl Kingsford | Bioinformatics | 2011 | 21217122 | Yes |
3047 | 1215 | 1215.0 | 58.86 | 58.9 | ROC methodology in radiologic imaging. | C E Metz | Invest Radiol | 1986 | 3095258 | No |
3048 | 1215 | 1215.0 | 30.14 | 30.1 | Autistic disturbances of affective contact. | L Kanner | Acta Paedopsychiatr | 1968 | 4880460 | Yes |
3049 | 7290 | 1215.0 | 135.05 | 22.5 | Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. | S M Elbashir, J Harborth, W Lendeckel, A Yalcin, K Weber, T Tuschl | Nature | 2001 | 11373684 | Yes |
3050 | 1215 | 1215.0 | 32.67 | 32.7 | Core affect and the psychological construction of emotion. | James A Russell | Psychol Rev | 2003 | 12529060 | No |
3051 | 1215 | 1215.0 | 31.47 | 31.5 | Q-ball imaging. | David S Tuch | Magn Reson Med | 2004 | 15562495 | Yes |
3052 | 2430 | 1215.0 | 97.76 | 48.9 | Systematic review of the health benefits of physical activity and fitness in school-aged children and youth. | Ian Janssen, Allana G Leblanc | Int J Behav Nutr Phys Act | 2010 | 20459784 | Yes |
3053 | 1214 | 1214.0 | 16.06 | 16.1 | The concept of immunological surveillance. | F M Burnet | Prog Exp Tumor Res | 1970 | 4921480 | No |
3054 | 1214 | 1214.0 | 25.13 | 25.1 | Caspase structure, proteolytic substrates, and function during apoptotic cell death. | D W Nicholson | Cell Death Differ | 1999 | 10578171 | No |
3055 | 2428 | 1214.0 | 63.86 | 31.9 | A neurotrophic model for stress-related mood disorders. | Ronald S Duman, Lisa M Monteggia | Biol Psychiatry | 2006 | 16631126 | No |
3056 | 1214 | 1214.0 | 34.14 | 34.1 | Electrochemical glucose biosensors. | Joseph Wang | Chem Rev | 2008 | 18154363 | No |
3057 | 1213 | 1213.0 | 29.35 | 29.4 | Bcl-2 initiates a new category of oncogenes: regulators of cell death. | S J Korsmeyer | Blood | 1992 | 1498330 | No |
3058 | 2426 | 1213.0 | 78.58 | 39.3 | Atomic structure and chemistry of human serum albumin. | X M He, D C Carter | Nature | 1992 | 1630489 | Yes |
3059 | 2426 | 1213.0 | 94.5 | 47.2 | A simple method to assess exercise behavior in the community. | G Godin, R J Shephard | Can J Appl Sport Sci | 1985 | 4053261 | Yes |
3060 | 1213 | 1213.0 | 25.04 | 25.0 | Platelets in atherothrombosis. | Zaverio M Ruggeri | Nat Med | 2002 | 12411949 | No |
3061 | 1213 | 1213.0 | 23.17 | 23.2 | Lipid rafts: elusive or illusive? | Sean Munro | Cell | 2003 | 14622593 | No |
3062 | 1213 | 1213.0 | 23.07 | 23.1 | IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. | Yong-Jun Liu | Annu Rev Immunol | 2005 | 15771572 | No |
3063 | 1213 | 1213.0 | 0.0 | 0.0 | Comparing individual means in the analysis of variance. | J W Tukey | Biometrics | 1949 | 18151955 | Yes |
3064 | 1213 | 1213.0 | 34.44 | 34.4 | A comprehensive definition for metabolic syndrome. | Paul L Huang | Dis Model Mech | 2009 | 19407331 | No |
3065 | 1213 | 1213.0 | 34.37 | 34.4 | MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship. | Amy E Pasquinelli | Nat Rev Genet | 2012 | 22411466 | No |
3066 | 3639 | 1213.0 | 245.04 | 81.7 | MAFFT online service: multiple sequence alignment, interactive sequence choice and visualization. | Kazutaka Katoh, John Rozewicki, Kazunori D Yamada | Brief Bioinform | 2019 | 28968734 | Yes |
3067 | 6060 | 1212.0 | 321.81 | 64.4 | Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype. | Daehwan Kim, Joseph M Paggi, Chanhee Park, Christopher Bennett, Steven L Salzberg | Nat Biotechnol | 2019 | 31375807 | Yes |
3068 | 4847 | 1211.8 | 170.51 | 42.6 | cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination. | Ali Punjani, John L Rubinstein, David J Fleet, Marcus A Brubaker | Nat Methods | 2017 | 28165473 | Yes |
3069 | 2423 | 1211.5 | 36.53 | 18.3 | High resolution acrylamide gel electrophoresis of histones. | S Panyim, R Chalkley | Arch Biochem Biophys | 1969 | 5778650 | Yes |
3070 | 2423 | 1211.5 | 59.43 | 29.7 | Heat-shock proteins, molecular chaperones, and the stress response: evolutionary and ecological physiology. | M E Feder, G E Hofmann | Annu Rev Physiol | 1999 | 10099689 | No |
3071 | 1211 | 1211.0 | 35.43 | 35.4 | Analyzing the mosaic structure of genes. | J M Smith | J Mol Evol | 1992 | 1556748 | No |
3072 | 2422 | 1211.0 | 62.54 | 31.3 | Statistical tests of neutrality of mutations. | Y X Fu, W H Li | Genetics | 1993 | 8454210 | Yes |
3073 | 1211 | 1211.0 | 32.77 | 32.8 | The emotional dog and its rational tail: a social intuitionist approach to moral judgment. | J Haidt | Psychol Rev | 2001 | 11699120 | Yes |
3074 | 1211 | 1211.0 | 51.07 | 51.1 | The use of the Center for Epidemiologic Studies Depression Scale in adolescents and young adults. | L S Radloff | J Youth Adolesc | 1991 | 24265004 | Yes |
3075 | 2421 | 1210.5 | 100.81 | 50.4 | Moving towards best practice when using inverse probability of treatment weighting (IPTW) using the propensity score to estimate causal treatment effects in observational studies. | Peter C Austin, Elizabeth A Stuart | Stat Med | 2015 | 26238958 | No |
3076 | 1210 | 1210.0 | 40.78 | 40.8 | The deadly quartet. Upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension. | N M Kaplan | Arch Intern Med | 1989 | 2662932 | No |
3077 | 1210 | 1210.0 | 48.55 | 48.5 | Bacterial adherence: adhesin-receptor interactions mediating the attachment of bacteria to mucosal surface. | E H Beachey | J Infect Dis | 1981 | 7014727 | No |
3078 | 2420 | 1210.0 | 52.3 | 26.1 | Toll-like receptors in innate immunity. | Kiyoshi Takeda, Shizuo Akira | Int Immunol | 2005 | 15585605 | No |
3079 | 1210 | 1210.0 | 76.39 | 76.4 | Cell death: a review of the major forms of apoptosis, necrosis and autophagy. | Mark S D'Arcy | Cell Biol Int | 2019 | 30958602 | No |
3080 | 2419 | 1209.5 | 48.89 | 24.4 | Learning the parts of objects by non-negative matrix factorization. | D D Lee, H S Seung | Nature | 1999 | 10548103 | Yes |
3081 | 1209 | 1209.0 | 52.45 | 52.5 | Campylobacter enteritis: a "new" disease. | M B Skirrow | Br Med J | 1977 | 871765 | Yes |
3082 | 1209 | 1209.0 | 40.37 | 40.4 | Volumetric modulated arc therapy: IMRT in a single gantry arc. | Karl Otto | Med Phys | 2008 | 18293586 | Yes |
3083 | 3625 | 1208.3 | 86.94 | 29.0 | Astrocyte-endothelial interactions at the blood-brain barrier. | N Joan Abbott, Lars Rönnbäck, Elisabeth Hansson | Nat Rev Neurosci | 2006 | 16371949 | No |
3084 | 1208 | 1208.0 | 24.88 | 24.9 | Morphogenetic roles of classic cadherins. | M Takeichi | Curr Opin Cell Biol | 1995 | 8573335 | No |
3085 | 1208 | 1208.0 | 30.46 | 30.5 | Disorders of iron metabolism. | N C Andrews | N Engl J Med | 1999 | 10607817 | No |
3086 | 1208 | 1208.0 | 20.88 | 20.9 | Stem cells: units of development, units of regeneration, and units in evolution. | I L Weissman | Cell | 2000 | 10647940 | No |
3087 | 1208 | 1208.0 | 32.32 | 32.3 | Production and scavenging of reactive oxygen species in chloroplasts and their functions. | Kozi Asada | Plant Physiol | 2006 | 16760493 | Yes |
3088 | 2415 | 1207.5 | 63.04 | 31.5 | Imaging cognition II: An empirical review of 275 PET and fMRI studies. | R Cabeza, L Nyberg | J Cogn Neurosci | 2000 | 10769304 | No |
3089 | 1207 | 1207.0 | 33.14 | 33.1 | Normalization of cell responses in cat striate cortex. | D J Heeger | Vis Neurosci | 1992 | 1504027 | Yes |
3090 | 1207 | 1207.0 | 38.58 | 38.6 | Linkage map of Escherichia coli K-12, edition 7. | B J Bachmann | Microbiol Rev | 1983 | 6348505 | No |
3091 | 2414 | 1207.0 | 64.47 | 32.2 | Leukocyte-endothelial adhesion molecules. | T M Carlos, J M Harlan | Blood | 1994 | 7522621 | No |
3092 | 1207 | 1207.0 | 33.49 | 33.5 | Papillary and follicular thyroid carcinoma. | M J Schlumberger | N Engl J Med | 1998 | 9445411 | No |
3093 | 3621 | 1207.0 | 101.89 | 34.0 | Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. | H King, R E Aubert, W H Herman | Diabetes Care | 1998 | 9727886 | Yes |
3094 | 1207 | 1207.0 | 48.75 | 48.8 | The PEDro scale is a valid measure of the methodological quality of clinical trials: a demographic study. | Natalie A de Morton | Aust J Physiother | 2009 | 19463084 | Yes |
3095 | 2413 | 1206.5 | 203.75 | 101.9 | Radiological demarcation of cemented sockets in total hip replacement. | J G DeLee, J Charnley | Clin Orthop Relat Res | 1976 | 991504 | Yes |
3096 | 2413 | 1206.5 | 65.46 | 32.7 | Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis. | J A Sterne, M Egger | J Clin Epidemiol | 2001 | 11576817 | Yes |
3097 | 2413 | 1206.5 | 126.51 | 63.3 | Studies of marine planktonic diatoms. I. Cyclotella nana Hustedt, and Detonula confervacea (cleve) Gran. | R R Guillard, J H Ryther | Can J Microbiol | 1962 | 13902807 | Yes |
3098 | 2412 | 1206.0 | 97.05 | 48.5 | The N1 wave of the human electric and magnetic response to sound: a review and an analysis of the component structure. | R Näätänen, T Picton | Psychophysiology | 1987 | 3615753 | Yes |
3099 | 2412 | 1206.0 | 46.28 | 23.1 | Dynamic instability of microtubule growth. | T Mitchison, M Kirschner | Nature | 1984 | 6504138 | Yes |
3100 | 3618 | 1206.0 | 72.92 | 24.3 | Large-scale analysis of the yeast proteome by multidimensional protein identification technology. | M P Washburn, D Wolters, J R Yates | Nat Biotechnol | 2001 | 11231557 | Yes |
3101 | 4824 | 1206.0 | 130.49 | 32.6 | Measurement of the elastic properties and intrinsic strength of monolayer graphene. | Changgu Lee, Xiaoding Wei, Jeffrey W Kysar, James Hone | Science | 2008 | 18635798 | Yes |
3102 | 1206 | 1206.0 | 33.71 | 33.7 | Atomic layer deposition: an overview. | Steven M George | Chem Rev | 2010 | 19947596 | Yes |
3103 | 2410 | 1205.0 | 59.61 | 29.8 | Rising incidence of hepatocellular carcinoma in the United States. | H B El-Serag, A C Mason | N Engl J Med | 1999 | 10072408 | Yes |
3104 | 1205 | 1205.0 | 31.4 | 31.4 | Chronic mild stress (CMS) revisited: consistency and behavioural-neurobiological concordance in the effects of CMS. | Paul Willner | Neuropsychobiology | 2005 | 16037678 | No |
3105 | 1205 | 1205.0 | 25.2 | 25.2 | The advantages and disadvantages of being polyploid. | Luca Comai | Nat Rev Genet | 2005 | 16304599 | No |
3106 | 3614 | 1204.7 | 73.39 | 24.5 | Toll-like receptors: critical proteins linking innate and acquired immunity. | S Akira, K Takeda, T Kaisho | Nat Immunol | 2001 | 11477402 | No |
3107 | 2409 | 1204.5 | 71.66 | 35.8 | Recent advances in the phencyclidine model of schizophrenia. | D C Javitt, S R Zukin | Am J Psychiatry | 1991 | 1654746 | No |
3108 | 2409 | 1204.5 | 49.8 | 24.9 | Atherosclerosis. the road ahead. | C K Glass, J L Witztum | Cell | 2001 | 11239408 | No |
3109 | 2409 | 1204.5 | 71.53 | 35.8 | Plasmonics for improved photovoltaic devices. | Harry A Atwater, Albert Polman | Nat Mater | 2010 | 20168344 | Yes |
3110 | 1204 | 1204.0 | 32.7 | 32.7 | Diversity of group types, regulation, and function of phospholipase A2. | E A Dennis | J Biol Chem | 1994 | 8175726 | No |
3111 | 3611 | 1203.7 | 167.12 | 55.7 | Cross-cultural adaptation of health-related quality of life measures: literature review and proposed guidelines. | F Guillemin, C Bombardier, D Beaton | J Clin Epidemiol | 1993 | 8263569 | No |
3112 | 2407 | 1203.5 | 55.31 | 27.7 | Establishing, maintaining and modifying DNA methylation patterns in plants and animals. | Julie A Law, Steven E Jacobsen | Nat Rev Genet | 2010 | 20142834 | No |
3113 | 2406 | 1203.0 | 66.24 | 33.1 | Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. | R G Phillips, J E LeDoux | Behav Neurosci | 1992 | 1590953 | Yes |
3114 | 1203 | 1203.0 | 26.58 | 26.6 | Translating cell biology into therapeutic advances in Alzheimer's disease. | D J Selkoe | Nature | 1999 | 10392577 | No |
3115 | 2406 | 1203.0 | 70.22 | 35.1 | Type 2 diabetes as an inflammatory disease. | Marc Y Donath, Steven E Shoelson | Nat Rev Immunol | 2011 | 21233852 | No |
3116 | 2406 | 1203.0 | 139.33 | 69.7 | Breast Cancer Treatment: A Review. | Adrienne G Waks, Eric P Winer | JAMA | 2019 | 30667505 | No |
3117 | 2404 | 1202.0 | 115.37 | 57.7 | Research diagnostic criteria for temporomandibular disorders: review, criteria, examinations and specifications, critique. | S F Dworkin, L LeResche | J Craniomandib Disord | 1992 | 1298767 | No |
3118 | 1202 | 1202.0 | 19.65 | 19.6 | Studies on phosphatidylcholine vesicles. Formation and physical characteristics. | C Huang | Biochemistry | 1969 | 5777332 | Yes |
3119 | 1202 | 1202.0 | 28.04 | 28.0 | Intracellular protein topogenesis. | G Blobel | Proc Natl Acad Sci U S A | 1980 | 6929499 | Yes |
3120 | 1202 | 1202.0 | 25.62 | 25.6 | The finer things in X-ray diffraction data collection. | J W Pflugrath | Acta Crystallogr D Biol Crystallogr | 1999 | 10531521 | Yes |
3121 | 3603 | 1201.0 | 151.54 | 50.5 | Measurement of health status. Ascertaining the minimal clinically important difference. | R Jaeschke, J Singer, G H Guyatt | Control Clin Trials | 1989 | 2691207 | Yes |
3122 | 1201 | 1201.0 | 41.19 | 41.2 | Assay of intestinal disaccharidases. | A Dahlqvist | Anal Biochem | 1968 | 5636962 | Yes |
3123 | 1201 | 1201.0 | 73.92 | 73.9 | Impingement lesions. | C S Neer | Clin Orthop Relat Res | 1983 | 6825348 | Yes |
3124 | 1201 | 1201.0 | 27.02 | 27.0 | Mitochondrial transport of cations: channels, exchangers, and permeability transition. | P Bernardi | Physiol Rev | 1999 | 10508231 | No |
3125 | 1201 | 1201.0 | 25.73 | 25.7 | The myofibroblast in wound healing and fibrocontractive diseases. | G Gabbiani | J Pathol | 2003 | 12845617 | No |
3126 | 2402 | 1201.0 | 48.83 | 24.4 | NF-kappaB: linking inflammation and immunity to cancer development and progression. | Michael Karin, Florian R Greten | Nat Rev Immunol | 2005 | 16175180 | No |
3127 | 1201 | 1201.0 | 49.96 | 50.0 | CONSORT-EHEALTH: improving and standardizing evaluation reports of Web-based and mobile health interventions. | Gunther Eysenbach | J Med Internet Res | 2011 | 22209829 | No |
3128 | 10807 | 1200.8 | 274.3 | 30.5 | Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. | Cole Trapnell, Brian A Williams, Geo Pertea, Ali Mortazavi, Gordon Kwan, Marijke J van Baren, Steven L Salzberg, Barbara J Wold, Lior Pachter | Nat Biotechnol | 2010 | 20436464 | Yes |
3129 | 3602 | 1200.7 | 144.76 | 48.3 | Principles of nanoparticle design for overcoming biological barriers to drug delivery. | Elvin Blanco, Haifa Shen, Mauro Ferrari | Nat Biotechnol | 2015 | 26348965 | Yes |
3130 | 2401 | 1200.5 | 62.43 | 31.2 | Verification of protein structures: patterns of nonbonded atomic interactions. | C Colovos, T O Yeates | Protein Sci | 1993 | 8401235 | Yes |
3131 | 3601 | 1200.3 | 86.58 | 28.9 | Functional diversity of helper T lymphocytes. | A K Abbas, K M Murphy, A Sher | Nature | 1996 | 8893001 | No |
3132 | 1200 | 1200.0 | 35.17 | 35.2 | Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes. | W Sieghart | Pharmacol Rev | 1995 | 7568326 | No |
3133 | 1200 | 1200.0 | 28.03 | 28.0 | Matrix proteoglycans: from molecular design to cellular function. | R V Iozzo | Annu Rev Biochem | 1998 | 9759499 | No |
3134 | 1200 | 1200.0 | 28.58 | 28.6 | Metabolism and functions of glutathione in brain. | R Dringen | Prog Neurobiol | 2000 | 10880854 | No |
3135 | 2399 | 1199.5 | 67.95 | 34.0 | Titanium dioxide nanomaterials: synthesis, properties, modifications, and applications. | Xiaobo Chen, Samuel S Mao | Chem Rev | 2007 | 17590053 | Yes |
3136 | 1199 | 1199.0 | 37.99 | 38.0 | The pathogenesis of sepsis. | R C Bone | Ann Intern Med | 1991 | 1872494 | No |
3137 | 1199 | 1199.0 | 27.27 | 27.3 | Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms. | William C Aird | Circ Res | 2007 | 17272818 | No |
3138 | 5994 | 1198.8 | 201.67 | 40.3 | Posttraumatic stress disorder in the National Comorbidity Survey. | R C Kessler, A Sonnega, E Bromet, M Hughes, C B Nelson | Arch Gen Psychiatry | 1995 | 7492257 | Yes |
3139 | 5994 | 1198.8 | 168.76 | 33.8 | Quantitative assessment of tactile allodynia in the rat paw. | S R Chaplan, F W Bach, J W Pogrel, J M Chung, T L Yaksh | J Neurosci Methods | 1994 | 7990513 | Yes |
3140 | 11984 | 1198.4 | 300.1 | 30.0 | Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. | M Dominici, K Le Blanc, I Mueller, I Slaper-Cortenbach, Fc Marini, Ds Krause, Rj Deans, A Keating, Dj Prockop, Em Horwitz | Cytotherapy | 2006 | 16923606 | Yes |
3141 | 2396 | 1198.0 | 85.64 | 42.8 | Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells. | A Fabiato, F Fabiato | J Physiol (Paris) | 1979 | 533865 | Yes |
3142 | 1198 | 1198.0 | 29.88 | 29.9 | Hereditary cancer, oncogenes, and antioncogenes. | A G Knudson | Cancer Res | 1985 | 2983882 | Yes |
3143 | 2396 | 1198.0 | 52.95 | 26.5 | Transforming gene product of Rous sarcoma virus phosphorylates tyrosine. | T Hunter, B M Sefton | Proc Natl Acad Sci U S A | 1980 | 6246487 | Yes |
3144 | 1198 | 1198.0 | 30.21 | 30.2 | Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. | G Boden | Diabetes | 1997 | 8971073 | No |
3145 | 1198 | 1198.0 | 35.24 | 35.2 | The structure of common mental disorders. | R F Krueger | Arch Gen Psychiatry | 1999 | 10530634 | Yes |
3146 | 1198 | 1198.0 | 23.63 | 23.6 | Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. | Harold F Dvorak | J Clin Oncol | 2002 | 12409337 | No |
3147 | 3594 | 1198.0 | 90.75 | 30.2 | Methods in mammalian autophagy research. | Noboru Mizushima, Tamotsu Yoshimori, Beth Levine | Cell | 2010 | 20144757 | Yes |
3148 | 4790 | 1197.5 | 130.37 | 32.6 | Toxic potential of materials at the nanolevel. | Andre Nel, Tian Xia, Lutz Mädler, Ning Li | Science | 2006 | 16456071 | No |
3149 | 1197 | 1197.0 | 28.55 | 28.6 | A tension-based theory of morphogenesis and compact wiring in the central nervous system. | D C Van Essen | Nature | 1997 | 9002514 | Yes |
3150 | 1197 | 1197.0 | 0.0 | 0.0 | The perceptron: a probabilistic model for information storage and organization in the brain. | F Rosenblatt | Psychol Rev | 1958 | 13602029 | Yes |
3151 | 1197 | 1197.0 | 24.65 | 24.6 | Microsatellites: simple sequences with complex evolution. | Hans Ellegren | Nat Rev Genet | 2004 | 15153996 | No |
3152 | 1197 | 1197.0 | 39.63 | 39.6 | Mediators and mechanisms of change in psychotherapy research. | Alan E Kazdin | Annu Rev Clin Psychol | 2007 | 17716046 | No |
3153 | 1197 | 1197.0 | 28.58 | 28.6 | Correlates of protection induced by vaccination. | Stanley A Plotkin | Clin Vaccine Immunol | 2010 | 20463105 | No |
3154 | 2394 | 1197.0 | 70.99 | 35.5 | Mitochondrial fission, fusion, and stress. | Richard J Youle, Alexander M van der Bliek | Science | 2012 | 22936770 | No |
3155 | 1196 | 1196.0 | 25.82 | 25.8 | How neutrophils kill microbes. | Anthony W Segal | Annu Rev Immunol | 2005 | 15771570 | No |
3156 | 1195 | 1195.0 | 28.97 | 29.0 | The neuropathology of schizophrenia. A critical review of the data and their interpretation. | P J Harrison | Brain | 1999 | 10219775 | No |
3157 | 2390 | 1195.0 | 78.47 | 39.2 | Efficacy of the Theory of Planned Behaviour: a meta-analytic review. | C J Armitage, M Conner | Br J Soc Psychol | 2001 | 11795063 | Yes |
3158 | 2390 | 1195.0 | 50.99 | 25.5 | Blinded by the Light: The Growing Complexity of p53. | Karen H Vousden, Carol Prives | Cell | 2009 | 19410540 | No |
3159 | 2390 | 1195.0 | 94.61 | 47.3 | Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation. | Ulrich M Zanger, Matthias Schwab | Pharmacol Ther | 2013 | 23333322 | No |
3160 | 4773 | 1193.2 | 137.18 | 34.3 | Place navigation impaired in rats with hippocampal lesions. | R G Morris, P Garrud, J N Rawlins, J O'Keefe | Nature | 1982 | 7088155 | Yes |
3161 | 1193 | 1193.0 | 48.87 | 48.9 | Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). | S Safe | Crit Rev Toxicol | 1990 | 2124811 | No |
3162 | 1193 | 1193.0 | 39.05 | 39.0 | Checklists for improving rigour in qualitative research: a case of the tail wagging the dog? | R S Barbour | BMJ | 2001 | 11337448 | No |
3163 | 1193 | 1193.0 | 69.69 | 69.7 | Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig. | G D Winter | Nature | 1962 | 14007593 | Yes |
3164 | 2386 | 1193.0 | 48.61 | 24.3 | The mammalian unfolded protein response. | Martin Schröder, Randal J Kaufman | Annu Rev Biochem | 2005 | 15952902 | No |
3165 | 2385 | 1192.5 | 53.3 | 26.6 | Adaptive protein evolution at the Adh locus in Drosophila. | J H McDonald, M Kreitman | Nature | 1991 | 1904993 | Yes |
3166 | 2385 | 1192.5 | 76.94 | 38.5 | Physiological parameters in laboratory animals and humans. | B Davies, T Morris | Pharm Res | 1993 | 8378254 | No |
3167 | 1192 | 1192.0 | 28.47 | 28.5 | Rapid and sensitive sequence comparison with FASTP and FASTA. | W R Pearson | Methods Enzymol | 1990 | 2156132 | Yes |
3168 | 1192 | 1192.0 | 36.1 | 36.1 | The mysteries of lipoprotein(a). | G Utermann | Science | 1989 | 2530631 | No |
3169 | 1192 | 1192.0 | 24.97 | 25.0 | Epstein-Barr virus infection. | J I Cohen | N Engl J Med | 2000 | 10944566 | No |
3170 | 2384 | 1192.0 | 69.14 | 34.6 | Natural products as sources of new drugs over the last 25 years. | David J Newman, Gordon M Cragg | J Nat Prod | 2007 | 17309302 | No |
3171 | 3574 | 1191.3 | 106.99 | 35.7 | The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. | G Blessed, B E Tomlinson, M Roth | Br J Psychiatry | 1968 | 5662937 | Yes |
3172 | 3574 | 1191.3 | 93.98 | 31.3 | Improved vectors and genome-wide libraries for CRISPR screening. | Neville E Sanjana, Ophir Shalem, Feng Zhang | Nat Methods | 2014 | 25075903 | Yes |
3173 | 1191 | 1191.0 | 38.4 | 38.4 | Agents that increase the permeability of the outer membrane. | M Vaara | Microbiol Rev | 1992 | 1406489 | No |
3174 | 1191 | 1191.0 | 36.82 | 36.8 | Biosynthesis and metabolism of endothelium-derived nitric oxide. | L J Ignarro | Annu Rev Pharmacol Toxicol | 1990 | 2188578 | No |
3175 | 1191 | 1191.0 | 21.39 | 21.4 | Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes. | D Hanahan | Nature | 1985 | 2986015 | Yes |
3176 | 1191 | 1191.0 | 26.68 | 26.7 | The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression. | S J Collins | Blood | 1987 | 3311197 | No |
3177 | 2382 | 1191.0 | 73.41 | 36.7 | The reward circuit: linking primate anatomy and human imaging. | Suzanne N Haber, Brian Knutson | Neuropsychopharmacology | 2010 | 19812543 | No |
3178 | 10716 | 1190.7 | 353.63 | 39.3 | A novel potent vasoconstrictor peptide produced by vascular endothelial cells. | M Yanagisawa, H Kurihara, S Kimura, Y Tomobe, M Kobayashi, Y Mitsui, Y Yazaki, K Goto, T Masaki | Nature | 1988 | 2451132 | Yes |
3179 | 1190 | 1190.0 | 30.66 | 30.7 | The neurobiology of stress: from serendipity to clinical relevance. | B S McEwen | Brain Res | 2000 | 11119695 | No |
3180 | 1190 | 1190.0 | 23.48 | 23.5 | The Colorimetric Micro-Determination Of Non-Esterified Fatty Acids In Plasma. | W G Duncombe | Clin Chim Acta | 1964 | 14122498 | Yes |
3181 | 1190 | 1190.0 | 36.07 | 36.1 | Platelet-rich plasma: evidence to support its use. | Robert E Marx | J Oral Maxillofac Surg | 2004 | 15085519 | No |
3182 | 1190 | 1190.0 | 30.11 | 30.1 | Physiology and pathophysiology of purinergic neurotransmission. | Geoffrey Burnstock | Physiol Rev | 2007 | 17429044 | No |
3183 | 3569 | 1189.7 | 121.92 | 40.6 | The 'Trier Social Stress Test'--a tool for investigating psychobiological stress responses in a laboratory setting. | C Kirschbaum, K M Pirke, D H Hellhammer | Neuropsychobiology | 1993 | 8255414 | Yes |
3184 | 5948 | 1189.6 | 140.25 | 28.1 | Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. | T R Mosmann, H Cherwinski, M W Bond, M A Giedlin, R L Coffman | J Immunol | 1986 | 2419430 | Yes |
3185 | 1189 | 1189.0 | 36.51 | 36.5 | The somatic marker hypothesis and the possible functions of the prefrontal cortex. | A R Damasio | Philos Trans R Soc Lond B Biol Sci | 1996 | 8941953 | No |
3186 | 1189 | 1189.0 | 19.17 | 19.2 | Themes and variations on ubiquitylation. | A M Weissman | Nat Rev Mol Cell Biol | 2001 | 11265246 | No |
3187 | 1189 | 1189.0 | 34.08 | 34.1 | Medscape's response to the Institute of Medicine Report: Crossing the quality chasm: a new health system for the 21st century. | M Leavitt | MedGenMed | 2001 | 11549951 | No |
3188 | 1189 | 1189.0 | 0.0 | 0.0 | Voluntary strength and fatigue. | P A Merton | J Physiol | 1954 | 13152698 | Yes |
3189 | 2378 | 1189.0 | 51.95 | 26.0 | Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. | Jing Yang, Robert A Weinberg | Dev Cell | 2008 | 18539112 | No |
3190 | 3567 | 1189.0 | 93.04 | 31.0 | Matrix metalloproteinases: regulators of the tumor microenvironment. | Kai Kessenbrock, Vicki Plaks, Zena Werb | Cell | 2010 | 20371345 | No |
3191 | 2377 | 1188.5 | 102.72 | 51.4 | Numerical index of the discriminatory ability of typing systems: an application of Simpson's index of diversity. | P R Hunter, M A Gaston | J Clin Microbiol | 1988 | 3069867 | Yes |
3192 | 1188 | 1188.0 | 40.27 | 40.3 | An approach for the treatment of penile carcinoma. | R M Cabanas | Cancer | 1977 | 837331 | Yes |
3193 | 1188 | 1188.0 | 52.16 | 52.2 | Presynaptic regulation of the release of catecholamines. | S Z Langer | Pharmacol Rev | 1980 | 6267618 | Yes |
3194 | 2376 | 1188.0 | 74.38 | 37.2 | Antiseptics and disinfectants: activity, action, and resistance. | G McDonnell, A D Russell | Clin Microbiol Rev | 1999 | 9880479 | No |
3195 | 1188 | 1188.0 | 31.15 | 31.1 | A theory of magnitude: common cortical metrics of time, space and quantity. | Vincent Walsh | Trends Cogn Sci | 2003 | 14585444 | Yes |
3196 | 3564 | 1188.0 | 105.02 | 35.0 | SeaView version 4: A multiplatform graphical user interface for sequence alignment and phylogenetic tree building. | Manolo Gouy, Stéphane Guindon, Olivier Gascuel | Mol Biol Evol | 2010 | 19854763 | Yes |
3197 | 5938 | 1187.6 | 229.04 | 45.8 | Salmon provides fast and bias-aware quantification of transcript expression. | Rob Patro, Geet Duggal, Michael I Love, Rafael A Irizarry, Carl Kingsford | Nat Methods | 2017 | 28263959 | Yes |
3198 | 2375 | 1187.5 | 81.27 | 40.6 | The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis. | G P Chrousos, P W Gold | JAMA | 1992 | 1538563 | No |
3199 | 2375 | 1187.5 | 95.4 | 47.7 | Rapid procedure for detection and isolation of large and small plasmids. | C I Kado, S T Liu | J Bacteriol | 1981 | 7009583 | Yes |
3200 | 1187 | 1187.0 | 58.02 | 58.0 | The tension-stress effect on the genesis and growth of tissues. Part I. The influence of stability of fixation and soft-tissue preservation. | G A Ilizarov | Clin Orthop Relat Res | 1989 | 2910611 | Yes |
3201 | 1187 | 1187.0 | 16.1 | 16.1 | The nature and significance of platelet products in human plasma. | P Wolf | Br J Haematol | 1967 | 6025241 | Yes |
3202 | 1187 | 1187.0 | 33.06 | 33.1 | On the law of effect. | R J Herrnstein | J Exp Anal Behav | 1970 | 16811440 | Yes |
3203 | 2374 | 1187.0 | 48.81 | 24.4 | Regulation of translation initiation in eukaryotes: mechanisms and biological targets. | Nahum Sonenberg, Alan G Hinnebusch | Cell | 2009 | 19239892 | No |
3204 | 1187 | 1187.0 | 57.01 | 57.0 | The new statistics: why and how. | Geoff Cumming | Psychol Sci | 2014 | 24220629 | Yes |
3205 | 2373 | 1186.5 | 111.44 | 55.7 | Simultaneous single isotope radioenzymatic assay of plasma norepinephrine, epinephrine and dopamine. | J D Peuler, G A Johnson | Life Sci | 1977 | 904439 | Yes |
3206 | 1186 | 1186.0 | 66.97 | 67.0 | Nontuberculous mycobacteria and associated diseases. | E Wolinsky | Am Rev Respir Dis | 1979 | 369415 | No |
3207 | 1186 | 1186.0 | 42.99 | 43.0 | The case for motivated reasoning. | Z Kunda | Psychol Bull | 1990 | 2270237 | No |
3208 | 2372 | 1186.0 | 70.61 | 35.3 | Multiple significance tests: the Bonferroni method. | J M Bland, D G Altman | BMJ | 1995 | 7833759 | Yes |
3209 | 2371 | 1185.5 | 66.07 | 33.0 | Heterogeneous photocatalyst materials for water splitting. | Akihiko Kudo, Yugo Miseki | Chem Soc Rev | 2009 | 19088977 | Yes |
3210 | 2370 | 1185.0 | 76.96 | 38.5 | Quantitative determination of serum triglycerides by the use of enzymes. | G Bucolo, H David | Clin Chem | 1973 | 4703655 | Yes |
3211 | 3555 | 1185.0 | 72.04 | 24.0 | Cellular survival: a play in three Akts. | S R Datta, A Brunet, M E Greenberg | Genes Dev | 1999 | 10579998 | No |
3212 | 2370 | 1185.0 | 55.31 | 27.7 | ZINC--a free database of commercially available compounds for virtual screening. | John J Irwin, Brian K Shoichet | J Chem Inf Model | 2005 | 15667143 | Yes |
3213 | 2370 | 1185.0 | 105.56 | 52.8 | Functional Classification and Experimental Dissection of Long Noncoding RNAs. | Florian Kopp, Joshua T Mendell | Cell | 2018 | 29373828 | No |
3214 | 16582 | 1184.4 | 353.31 | 25.2 | Crystallography & NMR system: A new software suite for macromolecular structure determination. | A T Brünger, P D Adams, G M Clore, W L DeLano, P Gros, R W Grosse-Kunstleve, J S Jiang, J Kuszewski, M Nilges, N S Pannu, R J Read, L M Rice, T Simonson, G L Warren | Acta Crystallogr D Biol Crystallogr | 1998 | 9757107 | Yes |
3215 | 3553 | 1184.3 | 115.25 | 38.4 | Hepatocellular carcinoma. | Alejandro Forner, Josep M Llovet, Jordi Bruix | Lancet | 2012 | 22353262 | No |
3216 | 1184 | 1184.0 | 107.34 | 107.3 | The analysis of errors in orthodontic measurements. | W J Houston | Am J Orthod | 1983 | 6573846 | Yes |
3217 | 1184 | 1184.0 | 44.99 | 45.0 | Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes. | H V Gelboin | Physiol Rev | 1980 | 7001511 | No |
3218 | 1184 | 1184.0 | 17.64 | 17.6 | The Nature Of Herpes Zoster: A Long-Term Study And A New Hypothesis. | R E Hope-Simpson | Proc R Soc Med | 1965 | 14267505 | Yes |
3219 | 7104 | 1184.0 | 157.98 | 26.3 | Principal components analysis corrects for stratification in genome-wide association studies. | Alkes L Price, Nick J Patterson, Robert M Plenge, Michael E Weinblatt, Nancy A Shadick, David Reich | Nat Genet | 2006 | 16862161 | Yes |
3220 | 2367 | 1183.5 | 54.11 | 27.1 | Regulation of wound healing by growth factors and cytokines. | Sabine Werner, Richard Grose | Physiol Rev | 2003 | 12843410 | No |
3221 | 2367 | 1183.5 | 55.54 | 27.8 | Endometriosis. | Linda C Giudice, Lee C Kao | Lancet | 2004 | 15541453 | No |
3222 | 5916 | 1183.2 | 192.7 | 38.5 | Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. | D Steinberg, S Parthasarathy, T E Carew, J C Khoo, J L Witztum | N Engl J Med | 1989 | 2648148 | No |
3223 | 1183 | 1183.0 | 28.63 | 28.6 | Testicular biopsy score count--a method for registration of spermatogenesis in human testes: normal values and results in 335 hypogonadal males. | S G Johnsen | Hormones | 1970 | 5527187 | Yes |
3224 | 1183 | 1183.0 | 25.62 | 25.6 | r8s: inferring absolute rates of molecular evolution and divergence times in the absence of a molecular clock. | Michael J Sanderson | Bioinformatics | 2003 | 12538260 | Yes |
3225 | 1183 | 1183.0 | 0.0 | 0.0 | A simple method of increasing the adhesion of acrylic filling materials to enamel surfaces. | M G Buonocore | J Dent Res | 1955 | 13271655 | Yes |
3226 | 1183 | 1183.0 | 49.44 | 49.4 | The prevalence of DSM-IV attention-deficit/hyperactivity disorder: a meta-analytic review. | Erik G Willcutt | Neurotherapeutics | 2012 | 22976615 | No |
3227 | 2365 | 1182.5 | 63.22 | 31.6 | A new local density functional for main-group thermochemistry, transition metal bonding, thermochemical kinetics, and noncovalent interactions. | Yan Zhao, Donald G Truhlar | J Chem Phys | 2006 | 17129083 | Yes |
3228 | 2364 | 1182.0 | 72.72 | 36.4 | Theoretical studies of enzymic reactions: dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme. | A Warshel, M Levitt | J Mol Biol | 1976 | 985660 | Yes |
3229 | 1182 | 1182.0 | 48.92 | 48.9 | How neuroinflammation contributes to neurodegeneration. | Richard M Ransohoff | Science | 2016 | 27540165 | No |
3230 | 4726 | 1181.5 | 105.82 | 26.5 | Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. | J E Walker, M Saraste, M J Runswick, N J Gay | EMBO J | 1982 | 6329717 | Yes |
3231 | 2363 | 1181.5 | 42.15 | 21.1 | Hedgehog signaling in animal development: paradigms and principles. | P W Ingham, A P McMahon | Genes Dev | 2001 | 11731473 | No |
3232 | 1181 | 1181.0 | 27.64 | 27.6 | The epidemiologic transition. A theory of the epidemiology of population change. | A R Omran | Milbank Mem Fund Q | 1971 | 5155251 | Yes |
3233 | 1181 | 1181.0 | 51.77 | 51.8 | Coping theory and research: past, present, and future. | R S Lazarus | Psychosom Med | 1993 | 8346332 | No |
3234 | 1181 | 1181.0 | 22.9 | 22.9 | Telomeres and human disease: ageing, cancer and beyond. | Maria A Blasco | Nat Rev Genet | 2005 | 16136653 | No |
3235 | 1181 | 1181.0 | 35.91 | 35.9 | A practical solution to the pervasive problems of p values. | Eric-Jan Wagenmakers | Psychon Bull Rev | 2007 | 18087943 | Yes |
3236 | 2362 | 1181.0 | 70.91 | 35.5 | Stochastic relaxation, gibbs distributions, and the bayesian restoration of images. | S Geman, D Geman | IEEE Trans Pattern Anal Mach Intell | 1984 | 22499653 | Yes |
3237 | 3543 | 1181.0 | 106.68 | 35.6 | Development and applications of CRISPR-Cas9 for genome engineering. | Patrick D Hsu, Eric S Lander, Feng Zhang | Cell | 2014 | 24906146 | No |
3238 | 1180 | 1180.0 | 26.79 | 26.8 | Hybridization of denatured RNA transferred or dotted nitrocellulose paper. | P S Thomas | Methods Enzymol | 1983 | 6194404 | Yes |
3239 | 1180 | 1180.0 | 30.73 | 30.7 | Epidemiology of women and depression. | Ronald C Kessler | J Affect Disord | 2003 | 12646294 | Yes |
3240 | 2360 | 1180.0 | 55.83 | 27.9 | Toxoplasmosis. | J G Montoya, O Liesenfeld | Lancet | 2004 | 15194258 | No |
3241 | 1180 | 1180.0 | 44.15 | 44.1 | Review of the key results from the Swedish Obese Subjects (SOS) trial - a prospective controlled intervention study of bariatric surgery. | L Sjöström | J Intern Med | 2013 | 23163728 | No |
3242 | 4719 | 1179.8 | 90.12 | 22.5 | Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. | L Alexopoulou, A C Holt, R Medzhitov, R A Flavell | Nature | 2001 | 11607032 | Yes |
3243 | 3539 | 1179.7 | 90.63 | 30.2 | Towards a natural system of organisms: proposal for the domains Archaea, Bacteria, and Eucarya. | C R Woese, O Kandler, M L Wheelis | Proc Natl Acad Sci U S A | 1990 | 2112744 | Yes |
3244 | 2359 | 1179.5 | 43.4 | 21.7 | Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. | C Li, W H Wong | Proc Natl Acad Sci U S A | 2001 | 11134512 | Yes |
3245 | 7076 | 1179.3 | 204.43 | 34.1 | The unity and diversity of executive functions and their contributions to complex "Frontal Lobe" tasks: a latent variable analysis. | A Miyake, N P Friedman, M J Emerson, A H Witzki, A Howerter, T D Wager | Cogn Psychol | 2000 | 10945922 | Yes |
3246 | 1179 | 1179.0 | 38.99 | 39.0 | Interleukin-1 and the pathogenesis of the acute-phase response. | C A Dinarello | N Engl J Med | 1984 | 6208485 | No |
3247 | 2358 | 1179.0 | 48.32 | 24.2 | Toll-like receptors in the induction of the innate immune response. | A Aderem, R J Ulevitch | Nature | 2000 | 10963608 | No |
3248 | 2358 | 1179.0 | 71.49 | 35.7 | Self-management education: history, definition, outcomes, and mechanisms. | Kate R Lorig, Halsted Holman | Ann Behav Med | 2003 | 12867348 | No |
3249 | 1179 | 1179.0 | 23.69 | 23.7 | Liver regeneration: from myth to mechanism. | Rebecca Taub | Nat Rev Mol Cell Biol | 2004 | 15459664 | No |
3250 | 2358 | 1179.0 | 52.72 | 26.4 | The Polycomb complex PRC2 and its mark in life. | Raphaël Margueron, Danny Reinberg | Nature | 2011 | 21248841 | No |
3251 | 8250 | 1178.6 | 161.16 | 23.0 | Exploration, normalization, and summaries of high density oligonucleotide array probe level data. | Rafael A Irizarry, Bridget Hobbs, Francois Collin, Yasmin D Beazer-Barclay, Kristen J Antonellis, Uwe Scherf, Terence P Speed | Biostatistics | 2003 | 12925520 | Yes |
3252 | 2357 | 1178.5 | 87.69 | 43.8 | Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. | H Esterbauer, K H Cheeseman | Methods Enzymol | 1990 | 2233308 | Yes |
3253 | 3535 | 1178.3 | 89.31 | 29.8 | The widespread regulation of microRNA biogenesis, function and decay. | Jacek Krol, Inga Loedige, Witold Filipowicz | Nat Rev Genet | 2010 | 20661255 | No |
3254 | 2356 | 1178.0 | 79.79 | 39.9 | A simple index of Crohn's-disease activity. | R F Harvey, J M Bradshaw | Lancet | 1980 | 6102236 | Yes |
3255 | 2356 | 1178.0 | 69.41 | 34.7 | The capacity of visual working memory for features and conjunctions. | S J Luck, E K Vogel | Nature | 1997 | 9384378 | Yes |
3256 | 1178 | 1178.0 | 28.03 | 28.0 | Context and behavioral processes in extinction. | Mark E Bouton | Learn Mem | 2004 | 15466298 | No |
3257 | 2355 | 1177.5 | 100.76 | 50.4 | The lifelong effects of early childhood adversity and toxic stress. | Jack P Shonkoff, Andrew S Garner | Pediatrics | 2012 | 22201156 | Yes |
3258 | 2354 | 1177.0 | 66.41 | 33.2 | The low-density lipoprotein pathway and its relation to atherosclerosis. | J L Goldstein, M S Brown | Annu Rev Biochem | 1977 | 197883 | No |
3259 | 1177 | 1177.0 | 25.24 | 25.2 | Serine protease mechanism and specificity. | Lizbeth Hedstrom | Chem Rev | 2002 | 12475199 | No |
3260 | 1177 | 1177.0 | 23.13 | 23.1 | Preliminary Trial Of Carisoprodol In Multiple Sclerosis. | B Ashworth | Practitioner | 1964 | 14143329 | Yes |
3261 | 1177 | 1177.0 | 0.0 | 0.0 | Histological demonstration of mucin after periodic acid. | J F A McMANUS | Nature | 1946 | 20995486 | Yes |
3262 | 1177 | 1177.0 | 33.1 | 33.1 | Rethinking schizophrenia. | Thomas R Insel | Nature | 2010 | 21068826 | No |
3263 | 5884 | 1176.8 | 109.34 | 21.9 | The protein kinase complement of the human genome. | G Manning, D B Whyte, R Martinez, T Hunter, S Sudarsanam | Science | 2002 | 12471243 | No |
3264 | 1176 | 1176.0 | 36.08 | 36.1 | Context, time, and memory retrieval in the interference paradigms of Pavlovian learning. | M E Bouton | Psychol Bull | 1993 | 8346330 | No |
3265 | 1176 | 1176.0 | 32.38 | 32.4 | The induction of pain: an integrative review. | M J Millan | Prog Neurobiol | 1999 | 9987804 | No |
3266 | 2352 | 1176.0 | 73.51 | 36.8 | Mechanisms of fibrosis: therapeutic translation for fibrotic disease. | Thomas A Wynn, Thirumalai R Ramalingam | Nat Med | 2012 | 22772564 | No |
3267 | 2351 | 1175.5 | 80.29 | 40.1 | Mendelian randomization: genetic anchors for causal inference in epidemiological studies. | George Davey Smith, Gibran Hemani | Hum Mol Genet | 2014 | 25064373 | No |
3268 | 1175 | 1175.0 | 35.69 | 35.7 | MOPAC: a semiempirical molecular orbital program. | J J Stewart | J Comput Aided Mol Des | 1990 | 2197373 | No |
3269 | 1175 | 1175.0 | 30.82 | 30.8 | Pathogenesis of dengue: challenges to molecular biology. | S B Halstead | Science | 1988 | 3277268 | No |
3270 | 1175 | 1175.0 | 26.89 | 26.9 | Neurons with graded response have collective computational properties like those of two-state neurons. | J J Hopfield | Proc Natl Acad Sci U S A | 1984 | 6587342 | Yes |
3271 | 1175 | 1175.0 | 24.05 | 24.1 | Apoptosis in neurodegenerative disorders. | M P Mattson | Nat Rev Mol Cell Biol | 2000 | 11253364 | No |
3272 | 2350 | 1175.0 | 53.34 | 26.7 | Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival. | Josep M Llovet, Jordi Bruix | Hepatology | 2003 | 12540794 | No |
3273 | 2350 | 1175.0 | 48.43 | 24.2 | Protein aggregation and neurodegenerative disease. | Christopher A Ross, Michelle A Poirier | Nat Med | 2004 | 15272267 | No |
3274 | 3525 | 1175.0 | 91.62 | 30.5 | Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? | Dunyaporn Trachootham, Jerome Alexandre, Peng Huang | Nat Rev Drug Discov | 2009 | 19478820 | No |
3275 | 1175 | 1175.0 | 55.68 | 55.7 | Sleep health: can we define it? Does it matter? | Daniel J Buysse | Sleep | 2014 | 24470692 | Yes |
3276 | 7047 | 1174.5 | 240.69 | 40.1 | The occurrence of sleep-disordered breathing among middle-aged adults. | T Young, M Palta, J Dempsey, J Skatrud, S Weber, S Badr | N Engl J Med | 1993 | 8464434 | Yes |
3277 | 1174 | 1174.0 | 34.09 | 34.1 | Determinants of tumor blood flow: a review. | R K Jain | Cancer Res | 1988 | 3282647 | No |
3278 | 1174 | 1174.0 | 49.02 | 49.0 | A spreading-activation theory of retrieval in sentence production. | G S Dell | Psychol Rev | 1986 | 3749399 | Yes |
3279 | 1174 | 1174.0 | 31.17 | 31.2 | AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function. | D Grahame Hardie | Genes Dev | 2011 | 21937710 | No |
3280 | 1174 | 1174.0 | 61.4 | 61.4 | The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety. | Martins Ekor | Front Pharmacol | 2014 | 24454289 | No |
3281 | 3521 | 1173.7 | 70.66 | 23.6 | Predicting coiled coils from protein sequences. | A Lupas, M Van Dyke, J Stock | Science | 1991 | 2031185 | Yes |
3282 | 3521 | 1173.7 | 95.67 | 31.9 | Regulation of cancer cell metabolism. | Rob A Cairns, Isaac S Harris, Tak W Mak | Nat Rev Cancer | 2011 | 21258394 | No |
3283 | 2347 | 1173.5 | 30.36 | 15.2 | A Generalization Of The Retention Index System Including Linear Temperature Programmed Gas-Liquid Partition Chromatography. | H Vandendool, P D Kratz | J Chromatogr | 1963 | 14062605 | Yes |
3284 | 2346 | 1173.0 | 51.41 | 25.7 | Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. | William G Kaelin, Peter J Ratcliffe | Mol Cell | 2008 | 18498744 | No |
3285 | 1173 | 1173.0 | 47.37 | 47.4 | How does sexual minority stigma "get under the skin"? A psychological mediation framework. | Mark L Hatzenbuehler | Psychol Bull | 2009 | 19702379 | No |
3286 | 1172 | 1172.0 | 21.5 | 21.5 | Biological robustness. | Hiroaki Kitano | Nat Rev Genet | 2004 | 15520792 | No |
3287 | 1172 | 1172.0 | 26.93 | 26.9 | Transcriptional paradigms in mammalian mitochondrial biogenesis and function. | Richard C Scarpulla | Physiol Rev | 2008 | 18391175 | No |
3288 | 1172 | 1172.0 | 123.9 | 123.9 | COVID-19 Vaccine Hesitancy Worldwide: A Concise Systematic Review of Vaccine Acceptance Rates. | Malik Sallam | Vaccines (Basel) | 2021 | 33669441 | No |
3289 | 2343 | 1171.5 | 87.04 | 43.5 | Societal and individual determinants of medical care utilization in the United States. | R Andersen, J F Newman | Milbank Mem Fund Q Health Soc | 1973 | 4198894 | Yes |
3290 | 4685 | 1171.2 | 133.52 | 33.4 | GCTA: a tool for genome-wide complex trait analysis. | Jian Yang, S Hong Lee, Michael E Goddard, Peter M Visscher | Am J Hum Genet | 2011 | 21167468 | Yes |
3291 | 1171 | 1171.0 | 56.86 | 56.9 | Self-discrepancy: a theory relating self and affect. | E T Higgins | Psychol Rev | 1987 | 3615707 | Yes |
3292 | 2342 | 1171.0 | 50.04 | 25.0 | Deep tissue two-photon microscopy. | Fritjof Helmchen, Winfried Denk | Nat Methods | 2005 | 16299478 | No |
3293 | 4682 | 1170.5 | 108.93 | 27.2 | Base-calling of automated sequencer traces using phred. I. Accuracy assessment. | B Ewing, L Hillier, M C Wendl, P Green | Genome Res | 1998 | 9521921 | Yes |
3294 | 1170 | 1170.0 | 31.27 | 31.3 | 6-Hydroxy-dopamine induced degeneration of central monoamine neurons. | U Ungerstedt | Eur J Pharmacol | 1968 | 5718510 | Yes |
3295 | 2339 | 1169.5 | 66.81 | 33.4 | Relaxing the rule of ten events per variable in logistic and Cox regression. | Eric Vittinghoff, Charles E McCulloch | Am J Epidemiol | 2007 | 17182981 | Yes |
3296 | 2338 | 1169.0 | 36.68 | 18.3 | Theoretical aspects of DNA-protein interactions: co-operative and non-co-operative binding of large ligands to a one-dimensional homogeneous lattice. | J D McGhee, P H von Hippel | J Mol Biol | 1974 | 4416620 | Yes |
3297 | 1169 | 1169.0 | 11.56 | 11.6 | Pathologic anatomy of the pancreas in juvenile diabetes mellitus. | W Gepts | Diabetes | 1965 | 5318831 | Yes |
3298 | 1169 | 1169.0 | 43.55 | 43.5 | Second generation logarithmic estimates of single-pool variable volume Kt/V: an analysis of error. | J T Daugirdas | J Am Soc Nephrol | 1993 | 8305648 | Yes |
3299 | 1169 | 1169.0 | 20.13 | 20.1 | Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism. | M S Wold | Annu Rev Biochem | 1997 | 9242902 | No |
3300 | 2336 | 1168.0 | 71.47 | 35.7 | Solubilization of membranes by detergents. | A Helenius, K Simons | Biochim Biophys Acta | 1975 | 1091302 | No |
3301 | 1168 | 1168.0 | 39.33 | 39.3 | beta-Lactamases in laboratory and clinical resistance. | D M Livermore | Clin Microbiol Rev | 1995 | 8665470 | No |
3302 | 1168 | 1168.0 | 31.77 | 31.8 | Pharmacology of cannabinoid CB1 and CB2 receptors. | R G Pertwee | Pharmacol Ther | 1997 | 9336020 | No |
3303 | 2336 | 1168.0 | 44.8 | 22.4 | STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. | Hiroki Ishikawa, Glen N Barber | Nature | 2008 | 18724357 | Yes |
3304 | 2336 | 1168.0 | 64.56 | 32.3 | Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. | Patrick S Ward, Craig B Thompson | Cancer Cell | 2012 | 22439925 | No |
3305 | 3502 | 1167.3 | 76.39 | 25.5 | Hepatocellular carcinoma. | Josep M Llovet, Andrew Burroughs, Jordi Bruix | Lancet | 2003 | 14667750 | No |
3306 | 1167 | 1167.0 | 44.54 | 44.5 | Molecular aspects of ligand binding to serum albumin. | U Kragh-Hansen | Pharmacol Rev | 1981 | 7027277 | No |
3307 | 2334 | 1167.0 | 49.32 | 24.7 | Functions of lipid rafts in biological membranes. | D A Brown, E London | Annu Rev Cell Dev Biol | 1998 | 9891780 | No |
3308 | 2334 | 1167.0 | 61.94 | 31.0 | BODIPY dyes and their derivatives: syntheses and spectroscopic properties. | Aurore Loudet, Kevin Burgess | Chem Rev | 2007 | 17924696 | Yes |
3309 | 2333 | 1166.5 | 49.44 | 24.7 | Defining the role of mTOR in cancer. | David A Guertin, David M Sabatini | Cancer Cell | 2007 | 17613433 | No |
3310 | 3499 | 1166.3 | 140.67 | 46.9 | Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves. | A DeLean, P J Munson, D Rodbard | Am J Physiol | 1978 | 686171 | Yes |
3311 | 1166 | 1166.0 | 26.32 | 26.3 | Viruses in the sea. | Curtis A Suttle | Nature | 2005 | 16163346 | No |
3312 | 2331 | 1165.5 | 52.28 | 26.1 | Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission. | P van den Driessche, James Watmough | Math Biosci | 2002 | 12387915 | Yes |
3313 | 2331 | 1165.5 | 55.37 | 27.7 | ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis. | Benoît D'Autréaux, Michel B Toledano | Nat Rev Mol Cell Biol | 2007 | 17848967 | No |
3314 | 1165 | 1165.0 | 26.13 | 26.1 | Cadherins: a molecular family important in selective cell-cell adhesion. | M Takeichi | Annu Rev Biochem | 1990 | 2197976 | No |
3315 | 1165 | 1165.0 | 21.92 | 21.9 | Microarray data normalization and transformation. | John Quackenbush | Nat Genet | 2002 | 12454644 | No |
3316 | 1165 | 1165.0 | 30.39 | 30.4 | Time is brain--quantified. | Jeffrey L Saver | Stroke | 2006 | 16339467 | Yes |
3317 | 1165 | 1165.0 | 27.82 | 27.8 | What is a support vector machine? | William S Noble | Nat Biotechnol | 2006 | 17160063 | No |
3318 | 1164 | 1164.0 | 24.21 | 24.2 | Evolution of ageing. | T B Kirkwood | Nature | 1977 | 593350 | Yes |
3319 | 1164 | 1164.0 | 34.58 | 34.6 | Low-molecular-weight heparins. | J I Weitz | N Engl J Med | 1997 | 9278467 | No |
3320 | 1164 | 1164.0 | 25.72 | 25.7 | Effect of carvedilol on outcome after myocardial infarction in patients with left-ventricular dysfunction: the CAPRICORN randomised trial. | H J Dargie | Lancet | 2001 | 11356434 | Yes |
3321 | 1164 | 1164.0 | 0.0 | 0.0 | A chemical method for the determination of oestriol, oestrone and oestradiol in human urine. | J B Brown | Biochem J | 1955 | 14389222 | Yes |
3322 | 2328 | 1164.0 | 43.84 | 21.9 | Rho GTPases: biochemistry and biology. | Aron B Jaffe, Alan Hall | Annu Rev Cell Dev Biol | 2005 | 16212495 | No |
3323 | 2327 | 1163.5 | 45.38 | 22.7 | Multiple nuclear factors interact with the immunoglobulin enhancer sequences. | R Sen, D Baltimore | Cell | 1986 | 3091258 | Yes |
3324 | 2327 | 1163.5 | 50.16 | 25.1 | Lymphocyte homing and homeostasis. | E C Butcher, L J Picker | Science | 1996 | 8600538 | No |
3325 | 3489 | 1163.0 | 80.39 | 26.8 | Molecular weight estimation of polypeptide chains by electrophoresis in SDS-polyacrylamide gels. | A L Shapiro, E Viñuela, J V Maizel | Biochem Biophys Res Commun | 1967 | 4861258 | Yes |
3326 | 1163 | 1163.0 | 28.02 | 28.0 | Mode of action of membrane active antimicrobial peptides. | Yechiel Shai | Biopolymers | 2002 | 12491537 | No |
3327 | 1163 | 1163.0 | 0.0 | 0.0 | The cytoarchitectonic organization of the spinal cord in the cat. | B Rexed | J Comp Neurol | 1952 | 14946260 | Yes |
3328 | 2325 | 1162.5 | 67.13 | 33.6 | Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. | P Brugada, J Brugada | J Am Coll Cardiol | 1992 | 1309182 | Yes |
3329 | 1162 | 1162.0 | 34.77 | 34.8 | Effect of anoxia on ion distribution in the brain. | A J Hansen | Physiol Rev | 1985 | 3880896 | No |
3330 | 2324 | 1162.0 | 47.73 | 23.9 | Plant pathogens and integrated defence responses to infection. | J L Dangl, J D Jones | Nature | 2001 | 11459065 | No |
3331 | 1162 | 1162.0 | 34.28 | 34.3 | Cognitive and affective development in adolescence. | Laurence Steinberg | Trends Cogn Sci | 2005 | 15668099 | No |
3332 | 1162 | 1162.0 | 28.44 | 28.4 | Formation and function of the myofibroblast during tissue repair. | Boris Hinz | J Invest Dermatol | 2007 | 17299435 | No |
3333 | 8129 | 1161.3 | 250.77 | 35.8 | Toxicity and response criteria of the Eastern Cooperative Oncology Group. | M M Oken, R H Creech, D C Tormey, J Horton, T E Davis, E T McFadden, P P Carbone | Am J Clin Oncol | 1982 | 7165009 | Yes |
3334 | 1161 | 1161.0 | 30.64 | 30.6 | Presynaptic regulation of catecholamine release. | S Z Langer | Biochem Pharmacol | 1974 | 4617579 | No |
3335 | 1161 | 1161.0 | 35.98 | 36.0 | Strategies of antioxidant defense. | H Sies | Eur J Biochem | 1993 | 7688300 | No |
3336 | 1161 | 1161.0 | 35.98 | 36.0 | The collagen family. | Sylvie Ricard-Blum | Cold Spring Harb Perspect Biol | 2011 | 21421911 | No |
3337 | 2321 | 1160.5 | 50.74 | 25.4 | Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set. | N Sreerama, R W Woody | Anal Biochem | 2000 | 11112271 | Yes |
3338 | 1160 | 1160.0 | 33.21 | 33.2 | The role of rumination in depressive disorders and mixed anxiety/depressive symptoms. | S Nolen-Hoeksema | J Abnorm Psychol | 2000 | 11016119 | Yes |
3339 | 1160 | 1160.0 | 23.66 | 23.7 | Understanding the odd science of aging. | Thomas B L Kirkwood | Cell | 2005 | 15734677 | No |
3340 | 1160 | 1160.0 | 24.58 | 24.6 | VEGF as a key mediator of angiogenesis in cancer. | Peter Carmeliet | Oncology | 2005 | 16301830 | No |
3341 | 2320 | 1160.0 | 73.22 | 36.6 | Central sensitization: a generator of pain hypersensitivity by central neural plasticity. | Alban Latremoliere, Clifford J Woolf | J Pain | 2009 | 19712899 | No |
3342 | 1160 | 1160.0 | 29.24 | 29.2 | Ovarian cancer development and metastasis. | Ernst Lengyel | Am J Pathol | 2010 | 20651229 | Yes |
3343 | 2320 | 1160.0 | 79.25 | 39.6 | A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation. | Walter J Paulus, Carsten Tschöpe | J Am Coll Cardiol | 2013 | 23684677 | No |
3344 | 4640 | 1160.0 | 248.9 | 62.2 | The Cambridge Structural Database. | Colin R Groom, Ian J Bruno, Matthew P Lightfoot, Suzanna C Ward | Acta Crystallogr B Struct Sci Cryst Eng Mater | 2016 | 27048719 | Yes |
3345 | 2319 | 1159.5 | 92.69 | 46.3 | Macrophages in Tissue Repair, Regeneration, and Fibrosis. | Thomas A Wynn, Kevin M Vannella | Immunity | 2016 | 26982353 | No |
3346 | 1159 | 1159.0 | 29.18 | 29.2 | Two-stage model of memory trace formation: a role for "noisy" brain states. | G Buzsáki | Neuroscience | 1989 | 2687720 | No |
3347 | 1159 | 1159.0 | 36.41 | 36.4 | Molecular biology of steroid hormone synthesis. | W L Miller | Endocr Rev | 1988 | 3061784 | No |
3348 | 1159 | 1159.0 | 44.11 | 44.1 | Freezing of living cells: mechanisms and implications. | P Mazur | Am J Physiol | 1984 | 6383068 | No |
3349 | 2318 | 1159.0 | 91.07 | 45.5 | Statistical methods for assessing measurement error (reliability) in variables relevant to sports medicine. | G Atkinson, A M Nevill | Sports Med | 1998 | 9820922 | No |
3350 | 1159 | 1159.0 | 28.46 | 28.5 | Immortal time bias in pharmaco-epidemiology. | Samy Suissa | Am J Epidemiol | 2008 | 18056625 | No |
3351 | 2318 | 1159.0 | 61.95 | 31.0 | Mechanisms of mitophagy. | Richard J Youle, Derek P Narendra | Nat Rev Mol Cell Biol | 2011 | 21179058 | No |
3352 | 2317 | 1158.5 | 50.44 | 25.2 | Esophageal cancer. | Peter C Enzinger, Robert J Mayer | N Engl J Med | 2003 | 14657432 | No |
3353 | 1158 | 1158.0 | 20.55 | 20.6 | Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation. | Eric C Lai | Nat Genet | 2002 | 11896390 | Yes |
3354 | 1158 | 1158.0 | 36.65 | 36.6 | Social support and health: a review of physiological processes potentially underlying links to disease outcomes. | Bert N Uchino | J Behav Med | 2006 | 16758315 | No |
3355 | 1158 | 1158.0 | 58.15 | 58.1 | Systematic text condensation: a strategy for qualitative analysis. | Kirsti Malterud | Scand J Public Health | 2012 | 23221918 | Yes |
3356 | 6947 | 1157.8 | 222.54 | 37.1 | The Molecular Signatures Database (MSigDB) hallmark gene set collection. | Arthur Liberzon, Chet Birger, Helga Thorvaldsdóttir, Mahmoud Ghandi, Jill P Mesirov, Pablo Tamayo | Cell Syst | 2015 | 26771021 | Yes |
3357 | 2315 | 1157.5 | 43.6 | 21.8 | NF-kappaB at the crossroads of life and death. | Michael Karin, Anning Lin | Nat Immunol | 2002 | 11875461 | No |
3358 | 2315 | 1157.5 | 51.28 | 25.6 | microRNA functions. | Natascha Bushati, Stephen M Cohen | Annu Rev Cell Dev Biol | 2007 | 17506695 | No |
3359 | 2314 | 1157.0 | 65.2 | 32.6 | Growth of a rat neuroblastoma cell line in serum-free supplemented medium. | J E Bottenstein, G H Sato | Proc Natl Acad Sci U S A | 1979 | 284369 | Yes |
3360 | 1157 | 1157.0 | 24.12 | 24.1 | Version 1.2 of the Crystallography and NMR system. | Axel T Brunger | Nat Protoc | 2007 | 18007608 | Yes |
3361 | 1157 | 1157.0 | 0.0 | 0.0 | Observations on the isolated phrenic nerve diaphragm preparation of the rat. | E Bulbring | Br J Pharmacol Chemother | 1946 | 20999334 | Yes |
3362 | 6941 | 1156.8 | 157.96 | 26.3 | Staging of brain pathology related to sporadic Parkinson's disease. | Heiko Braak, Kelly Del Tredici, Udo Rüb, Rob A I de Vos, Ernst N H Jansen Steur, Eva Braak | Neurobiol Aging | 2003 | 12498954 | Yes |
3363 | 1156 | 1156.0 | 60.57 | 60.6 | A "rationalized" arcsine transform. | G A Studebaker | J Speech Hear Res | 1985 | 4046587 | Yes |
3364 | 1156 | 1156.0 | 21.78 | 21.8 | Biogenic amines and the states of sleep. | M Jouvet | Science | 1969 | 4303225 | No |
3365 | 1156 | 1156.0 | 11.94 | 11.9 | Autoradiographic and histological studies of postnatal neurogenesis. IV. Cell proliferation and migration in the anterior forebrain, with special reference to persisting neurogenesis in the olfactory bulb. | J Altman | J Comp Neurol | 1969 | 5361244 | Yes |
3366 | 1156 | 1156.0 | 24.31 | 24.3 | RNA metabolism in the HeLa cell nucleus. | S Penman | J Mol Biol | 1966 | 5961144 | Yes |
3367 | 2312 | 1156.0 | 130.71 | 65.4 | Adenosine 3',5'-phosphate in biological materials. I. Purification and properties of cyclic 3',5'-nucleotide phosphodiesterase and use of this enzyme to characterize adenosine 3',5'-phosphate in human urine. | R W Butcher, E W Sutherland | J Biol Chem | 1962 | 13875173 | Yes |
3368 | 1156 | 1156.0 | 25.19 | 25.2 | Next-generation DNA sequencing methods. | Elaine R Mardis | Annu Rev Genomics Hum Genet | 2008 | 18576944 | No |
3369 | 3467 | 1155.7 | 68.32 | 22.8 | SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. | Jay D Horton, Joseph L Goldstein, Michael S Brown | J Clin Invest | 2002 | 11994399 | No |
3370 | 3467 | 1155.7 | 83.38 | 27.8 | Mechanisms linking obesity to insulin resistance and type 2 diabetes. | Steven E Kahn, Rebecca L Hull, Kristina M Utzschneider | Nature | 2006 | 17167471 | No |
3371 | 2311 | 1155.5 | 86.7 | 43.4 | The Posttraumatic Growth Inventory: measuring the positive legacy of trauma. | R G Tedeschi, L G Calhoun | J Trauma Stress | 1996 | 8827649 | Yes |
3372 | 3465 | 1155.0 | 84.25 | 28.1 | High resolution two-dimensional electrophoresis of basic as well as acidic proteins. | P Z O'Farrell, H M Goodman, P H O'Farrell | Cell | 1977 | 23215 | Yes |
3373 | 1155 | 1155.0 | 36.37 | 36.4 | Relations between the statistics of natural images and the response properties of cortical cells. | D J Field | J Opt Soc Am A | 1987 | 3430225 | Yes |
3374 | 1155 | 1155.0 | 26.71 | 26.7 | Amyloid, the presenilins and Alzheimer's disease. | J Hardy | Trends Neurosci | 1997 | 9106355 | No |
3375 | 1155 | 1155.0 | 27.0 | 27.0 | Aptamers: an emerging class of molecules that rival antibodies in diagnostics. | S D Jayasena | Clin Chem | 1999 | 10471678 | No |
3376 | 1155 | 1155.0 | 31.66 | 31.7 | Riddle of biofilm resistance. | K Lewis | Antimicrob Agents Chemother | 2001 | 11257008 | No |
3377 | 1155 | 1155.0 | 22.12 | 22.1 | Regulation of cadherin-mediated adhesion in morphogenesis. | Barry M Gumbiner | Nat Rev Mol Cell Biol | 2005 | 16025097 | No |
3378 | 1155 | 1155.0 | 41.06 | 41.1 | Visual attention: the past 25 years. | Marisa Carrasco | Vision Res | 2011 | 21549742 | No |
3379 | 2309 | 1154.5 | 67.06 | 33.5 | Excitatory amino acids as a final common pathway for neurologic disorders. | S A Lipton, P A Rosenberg | N Engl J Med | 1994 | 7905600 | No |
3380 | 2309 | 1154.5 | 60.71 | 30.4 | Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance. | I Chopra, M Roberts | Microbiol Mol Biol Rev | 2001 | 11381101 | Yes |
3381 | 3463 | 1154.3 | 98.93 | 33.0 | A sensitive and reliable locomotor rating scale for open field testing in rats. | D M Basso, M S Beattie, J C Bresnahan | J Neurotrauma | 1995 | 7783230 | Yes |
3382 | 2308 | 1154.0 | 86.36 | 43.2 | The content validity index: are you sure you know what's being reported? Critique and recommendations. | Denise F Polit, Cheryl Tatano Beck | Res Nurs Health | 2006 | 16977646 | Yes |
3383 | 3461 | 1153.7 | 102.71 | 34.2 | HMMER web server: interactive sequence similarity searching. | Robert D Finn, Jody Clements, Sean R Eddy | Nucleic Acids Res | 2011 | 21593126 | Yes |
3384 | 2304 | 1152.0 | 46.38 | 23.2 | A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. | N C Andrews, D V Faller | Nucleic Acids Res | 1991 | 2041787 | Yes |
3385 | 1152 | 1152.0 | 53.45 | 53.5 | Analysis of Fickian and non-Fickian drug release from polymers. | N A Peppas | Pharm Acta Helv | 1985 | 4011621 | Yes |
3386 | 1152 | 1152.0 | 0.0 | 0.0 | The powerful placebo. | H K Beecher | J Am Med Assoc | 1955 | 13271123 | Yes |
3387 | 1152 | 1152.0 | 41.83 | 41.8 | Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms. | Tamás Rőszer | Mediators Inflamm | 2015 | 26089604 | No |
3388 | 2303 | 1151.5 | 61.87 | 30.9 | Mechanisms of biofilm resistance to antimicrobial agents. | T F Mah, G A O'Toole | Trends Microbiol | 2001 | 11166241 | No |
3389 | 4606 | 1151.5 | 214.69 | 53.7 | Genome sequence-based species delimitation with confidence intervals and improved distance functions. | Jan P Meier-Kolthoff, Alexander F Auch, Hans-Peter Klenk, Markus Göker | BMC Bioinformatics | 2013 | 23432962 | Yes |
3390 | 1151 | 1151.0 | 21.93 | 21.9 | Contingent genetic regulatory events in T lymphocyte activation. | G R Crabtree | Science | 1989 | 2783497 | Yes |
3391 | 1151 | 1151.0 | 29.53 | 29.5 | Selective coronary arteriography. I. A percutaneous transfemoral technic. | M P Judkins | Radiology | 1967 | 6048074 | Yes |
3392 | 1151 | 1151.0 | 31.48 | 31.5 | Leishmaniasis. | B L Herwaldt | Lancet | 1999 | 10513726 | No |
3393 | 1151 | 1151.0 | 31.66 | 31.7 | The locus coeruleus and noradrenergic modulation of cognition. | Susan J Sara | Nat Rev Neurosci | 2009 | 19190638 | No |
3394 | 1150 | 1150.0 | 29.08 | 29.1 | The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. | R A Jain | Biomaterials | 2000 | 11055295 | No |
3395 | 2300 | 1150.0 | 44.75 | 22.4 | Tumour-cell invasion and migration: diversity and escape mechanisms. | Peter Friedl, Katarina Wolf | Nat Rev Cancer | 2003 | 12724734 | No |
3396 | 1150 | 1150.0 | 22.27 | 22.3 | Inferences, questions and possibilities in Toll-like receptor signalling. | Bruce Beutler | Nature | 2004 | 15241424 | No |
3397 | 3450 | 1150.0 | 92.42 | 30.8 | Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. | Robert G Hart, Lesly A Pearce, Maria I Aguilar | Ann Intern Med | 2007 | 17577005 | Yes |
3398 | 3450 | 1150.0 | 84.24 | 28.1 | METAL: fast and efficient meta-analysis of genomewide association scans. | Cristen J Willer, Yun Li, Gonçalo R Abecasis | Bioinformatics | 2010 | 20616382 | Yes |
3399 | 1150 | 1150.0 | 31.96 | 32.0 | Neurophysiological and computational principles of cortical rhythms in cognition. | Xiao-Jing Wang | Physiol Rev | 2010 | 20664082 | No |
3400 | 2299 | 1149.5 | 70.92 | 35.5 | Role of oxidized low density lipoprotein in atherogenesis. | J L Witztum, D Steinberg | J Clin Invest | 1991 | 1752940 | No |
3401 | 2299 | 1149.5 | 75.76 | 37.9 | The complexity of NF-κB signaling in inflammation and cancer. | Bastian Hoesel, Johannes A Schmid | Mol Cancer | 2013 | 23915189 | No |
3402 | 1149 | 1149.0 | 42.36 | 42.4 | Omega-3 fatty acids in health and disease and in growth and development. | A P Simopoulos | Am J Clin Nutr | 1991 | 1908631 | No |
3403 | 1149 | 1149.0 | 0.0 | 0.0 | A sensitive method for the assay of 5-hydroxytryptamine. | J R Vane | Br J Pharmacol Chemother | 1957 | 13460242 | Yes |
3404 | 1149 | 1149.0 | 30.95 | 30.9 | Stronger Brønsted acids. | Takahiko Akiyama | Chem Rev | 2007 | 17983247 | Yes |
3405 | 1149 | 1149.0 | 27.99 | 28.0 | Nanoparticles, Proteins, and Nucleic Acids: Biotechnology Meets Materials Science. | Christof M Niemeyer | Angew Chem Int Ed Engl | 2001 | 29712109 | No |
3406 | 2296 | 1148.0 | 84.09 | 42.0 | The Modified Mini-Mental State (3MS) examination. | E L Teng, H C Chui | J Clin Psychiatry | 1987 | 3611032 | Yes |
3407 | 1148 | 1148.0 | 34.34 | 34.3 | Nature of Col E 1 plasmid replication in Escherichia coli in the presence of the chloramphenicol. | D B Clewell | J Bacteriol | 1972 | 4336693 | Yes |
3408 | 2296 | 1148.0 | 50.03 | 25.0 | Plasminogen: purification from human plasma by affinity chromatography. | D G Deutsch, E T Mertz | Science | 1970 | 5475635 | Yes |
3409 | 1148 | 1148.0 | 38.86 | 38.9 | Selective attention and the organization of visual information. | J Duncan | J Exp Psychol Gen | 1984 | 6240521 | Yes |
3410 | 1148 | 1148.0 | 21.91 | 21.9 | VEGF and the quest for tumour angiogenesis factors. | Napoleone Ferrara | Nat Rev Cancer | 2002 | 12360282 | No |
3411 | 4591 | 1147.8 | 262.39 | 65.6 | Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads. | Ryan R Wick, Louise M Judd, Claire L Gorrie, Kathryn E Holt | PLoS Comput Biol | 2017 | 28594827 | Yes |
3412 | 1147 | 1147.0 | 21.99 | 22.0 | Mechanisms and consequences of activation of protein kinase B/Akt. | J Downward | Curr Opin Cell Biol | 1998 | 9561851 | No |
3413 | 1147 | 1147.0 | 24.03 | 24.0 | Molecular imaging of cancer with positron emission tomography. | Sanjiv Sam Gambhir | Nat Rev Cancer | 2002 | 12209157 | No |
3414 | 2294 | 1147.0 | 51.62 | 25.8 | Shape-controlled synthesis of gold and silver nanoparticles. | Yugang Sun, Younan Xia | Science | 2002 | 12481134 | Yes |
3415 | 1147 | 1147.0 | 0.0 | 0.0 | Knee joint changes after meniscectomy. | T J Fairbank | J Bone Joint Surg Br | 1948 | 18894618 | Yes |
3416 | 1147 | 1147.0 | 38.46 | 38.5 | Globalization of diabetes: the role of diet, lifestyle, and genes. | Frank B Hu | Diabetes Care | 2011 | 21617109 | No |
3417 | 2293 | 1146.5 | 79.66 | 39.8 | A formula to estimate the approximate surface area if height and weight be known. 1916. | D Du Bois, E F Du Bois | Nutrition | 1989 | 2520314 | No |
3418 | 3439 | 1146.3 | 97.6 | 32.5 | Interpretation of changes in health-related quality of life: the remarkable universality of half a standard deviation. | Geoffrey R Norman, Jeff A Sloan, Kathleen W Wyrwich | Med Care | 2003 | 12719681 | No |
3419 | 1146 | 1146.0 | 32.01 | 32.0 | DNA topoisomerases. | M Gellert | Annu Rev Biochem | 1981 | 6267993 | No |
3420 | 1146 | 1146.0 | 24.04 | 24.0 | Stem cells in the central nervous system. | R McKay | Science | 1997 | 9082987 | No |
3421 | 1146 | 1146.0 | 25.87 | 25.9 | The columnar organization of the neocortex. | V B Mountcastle | Brain | 1997 | 9153131 | No |
3422 | 1146 | 1146.0 | 0.0 | 0.0 | Fertilizing capacity of spermatozoa deposited into the fallopian tubes. | M C Chang | Nature | 1951 | 14882325 | Yes |
3423 | 2292 | 1146.0 | 89.77 | 44.9 | Communication by Extracellular Vesicles: Where We Are and Where We Need to Go. | Mercedes Tkach, Clotilde Théry | Cell | 2016 | 26967288 | No |
3424 | 1145 | 1145.0 | 30.99 | 31.0 | Diseases of the mitochondrial DNA. | D C Wallace | Annu Rev Biochem | 1992 | 1497308 | No |
3425 | 1145 | 1145.0 | 25.55 | 25.6 | Estimating absolute rates of molecular evolution and divergence times: a penalized likelihood approach. | Michael J Sanderson | Mol Biol Evol | 2002 | 11752195 | Yes |
3426 | 2290 | 1145.0 | 42.61 | 21.3 | The druggable genome. | Andrew L Hopkins, Colin R Groom | Nat Rev Drug Discov | 2002 | 12209152 | No |
3427 | 1145 | 1145.0 | 24.79 | 24.8 | G-quartets 40 years later: from 5'-GMP to molecular biology and supramolecular chemistry. | Jeffery T Davis | Angew Chem Int Ed Engl | 2004 | 14755695 | No |
3428 | 4577 | 1144.2 | 110.63 | 27.7 | Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. | H Nielsen, J Engelbrecht, S Brunak, G von Heijne | Protein Eng | 1997 | 9051728 | Yes |
3429 | 2288 | 1144.0 | 60.43 | 30.2 | Analysis of gene control signals by DNA fusion and cloning in Escherichia coli. | M J Casadaban, S N Cohen | J Mol Biol | 1980 | 6997493 | Yes |
3430 | 1144 | 1144.0 | 31.02 | 31.0 | Venous thrombosis: a multicausal disease. | F R Rosendaal | Lancet | 1999 | 10209995 | No |
3431 | 1144 | 1144.0 | 20.31 | 20.3 | NFAT proteins: key regulators of T-cell development and function. | Fernando Macian | Nat Rev Immunol | 2005 | 15928679 | No |
3432 | 2288 | 1144.0 | 67.09 | 33.5 | Health effects of fine particulate air pollution: lines that connect. | C Arden Pope, Douglas W Dockery | J Air Waste Manag Assoc | 2006 | 16805397 | No |
3433 | 12578 | 1143.5 | 354.03 | 32.2 | International physical activity questionnaire: 12-country reliability and validity. | Cora L Craig, Alison L Marshall, Michael Sjöström, Adrian E Bauman, Michael L Booth, Barbara E Ainsworth, Michael Pratt, Ulf Ekelund, Agneta Yngve, James F Sallis, Pekka Oja | Med Sci Sports Exerc | 2003 | 12900694 | Yes |
3434 | 1143 | 1143.0 | 43.04 | 43.0 | Radioimmunological determination of human C-peptide in serum. | L G Heding | Diabetologia | 1975 | 1239396 | Yes |
3435 | 2286 | 1143.0 | 84.84 | 42.4 | Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes. | I B Wilson, P D Cleary | JAMA | 1995 | 7996652 | Yes |
3436 | 1143 | 1143.0 | 21.24 | 21.2 | The power and the promise of DNA methylation markers. | Peter W Laird | Nat Rev Cancer | 2003 | 12671664 | No |
3437 | 1143 | 1143.0 | 9.79 | 9.8 | A New Serum Type System In Man--The Lp System. | K Berg | Acta Pathol Microbiol Scand | 1963 | 14064818 | Yes |
3438 | 1143 | 1143.0 | 26.2 | 26.2 | Anatomy and regulation of the central melanocortin system. | Roger D Cone | Nat Neurosci | 2005 | 15856065 | No |
3439 | 3428 | 1142.7 | 105.94 | 35.3 | PedsQL 4.0: reliability and validity of the Pediatric Quality of Life Inventory version 4.0 generic core scales in healthy and patient populations. | J W Varni, M Seid, P S Kurtin | Med Care | 2001 | 11468499 | Yes |
3440 | 2285 | 1142.5 | 51.22 | 25.6 | Next-generation DNA sequencing. | Jay Shendure, Hanlee Ji | Nat Biotechnol | 2008 | 18846087 | Yes |
3441 | 3427 | 1142.3 | 108.99 | 36.3 | Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate. | G M Wahl, M Stern, G R Stark | Proc Natl Acad Sci U S A | 1979 | 291033 | Yes |
3442 | 1142 | 1142.0 | 31.85 | 31.9 | An improved fluorometric assay for DNA. | R T Hinegardner | Anal Biochem | 1971 | 5544593 | Yes |
3443 | 1142 | 1142.0 | 30.33 | 30.3 | Disseminating innovations in health care. | Donald M Berwick | JAMA | 2003 | 12697800 | Yes |
3444 | 1142 | 1142.0 | 31.12 | 31.1 | Cholinesterase inhibitors for Alzheimer's disease. | J Birks | Cochrane Database Syst Rev | 2006 | 16437532 | No |
3445 | 6849 | 1141.5 | 147.05 | 24.5 | Obesity is associated with macrophage accumulation in adipose tissue. | Stuart P Weisberg, Daniel McCann, Manisha Desai, Michael Rosenbaum, Rudolph L Leibel, Anthony W Ferrante | J Clin Invest | 2003 | 14679176 | Yes |
3446 | 2283 | 1141.5 | 81.88 | 40.9 | Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. | Claudio Franceschi, Judith Campisi | J Gerontol A Biol Sci Med Sci | 2014 | 24833586 | No |
3447 | 1141 | 1141.0 | 33.3 | 33.3 | Reducing children's television viewing to prevent obesity: a randomized controlled trial. | T N Robinson | JAMA | 1999 | 10546696 | Yes |
3448 | 1141 | 1141.0 | 0.0 | 0.0 | The degree of masculine differentiation of obesities: a factor determining predisposition to diabetes, atherosclerosis, gout, and uric calculous disease. | J Vague | Am J Clin Nutr | 1956 | 13282851 | Yes |
3449 | 2281 | 1140.5 | 93.4 | 46.7 | Tripartite model of anxiety and depression: psychometric evidence and taxonomic implications. | L A Clark, D Watson | J Abnorm Psychol | 1991 | 1918611 | No |
3450 | 2281 | 1140.5 | 66.8 | 33.4 | Nitric oxide synthases in mammals. | R G Knowles, S Moncada | Biochem J | 1994 | 7510950 | No |
3451 | 2281 | 1140.5 | 63.45 | 31.7 | Burden of major musculoskeletal conditions. | Anthony D Woolf, Bruce Pfleger | Bull World Health Organ | 2003 | 14710506 | No |
3452 | 1140 | 1140.0 | 28.72 | 28.7 | Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture. | I J Fidler | Cancer Res | 1990 | 1698118 | Yes |
3453 | 2280 | 1140.0 | 46.69 | 23.3 | Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. | G A Gonzalez, M R Montminy | Cell | 1989 | 2573431 | Yes |
3454 | 1140 | 1140.0 | 21.06 | 21.1 | Regulation of phosphoinositide-specific phospholipase C. | S G Rhee | Annu Rev Biochem | 2001 | 11395409 | No |
3455 | 2280 | 1140.0 | 71.12 | 35.6 | Long non-coding RNAs: new players in cell differentiation and development. | Alessandro Fatica, Irene Bozzoni | Nat Rev Genet | 2014 | 24296535 | No |
3456 | 2279 | 1139.5 | 50.44 | 25.2 | Obesity and insulin resistance. | B B Kahn, J S Flier | J Clin Invest | 2000 | 10953022 | No |
3457 | 1139 | 1139.0 | 33.96 | 34.0 | Unstable angina. A classification. | E Braunwald | Circulation | 1989 | 2752565 | Yes |
3458 | 1139 | 1139.0 | 23.15 | 23.1 | Differentiation and proliferation of hematopoietic stem cells. | M Ogawa | Blood | 1993 | 8499622 | No |
3459 | 1139 | 1139.0 | 33.08 | 33.1 | Modeling tracer kinetics in dynamic Gd-DTPA MR imaging. | P S Tofts | J Magn Reson Imaging | 1997 | 9039598 | No |
3460 | 1139 | 1139.0 | 67.94 | 67.9 | Diffusion-in-gel methods for immunological analysis. II. | O Ouchterlony | Prog Allergy | 1962 | 14482809 | Yes |
3461 | 1139 | 1139.0 | 30.55 | 30.6 | A toxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors. | Ron Hardman | Environ Health Perspect | 2006 | 16451849 | No |
3462 | 1139 | 1139.0 | 0.0 | 0.0 | A microchemical reaction resulting in the staining of polysaccharide structures in fixed tissue preparations. | R D Hotchkiss | Arch Biochem | 1948 | 18921848 | Yes |
3463 | 3416 | 1138.7 | 72.56 | 24.2 | A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. | M Serrano, G J Hannon, D Beach | Nature | 1993 | 8259215 | Yes |
3464 | 2277 | 1138.5 | 67.97 | 34.0 | Ischemia and reperfusion--from mechanism to translation. | Holger K Eltzschig, Tobias Eckle | Nat Med | 2011 | 22064429 | No |
3465 | 1138 | 1138.0 | 21.36 | 21.4 | The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities. | Y Yarden | Eur J Cancer | 2001 | 11597398 | No |
3466 | 1138 | 1138.0 | 29.68 | 29.7 | An introduction to data reduction: space-group determination, scaling and intensity statistics. | Philip R Evans | Acta Crystallogr D Biol Crystallogr | 2011 | 21460446 | Yes |
3467 | 3414 | 1138.0 | 118.68 | 39.6 | SCANPY: large-scale single-cell gene expression data analysis. | F Alexander Wolf, Philipp Angerer, Fabian J Theis | Genome Biol | 2018 | 29409532 | Yes |
3468 | 4551 | 1137.8 | 111.21 | 27.8 | Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. | Michael D Greicius, Ben Krasnow, Allan L Reiss, Vinod Menon | Proc Natl Acad Sci U S A | 2003 | 12506194 | Yes |
3469 | 3413 | 1137.7 | 90.71 | 30.2 | A nonparametric method for automatic correction of intensity nonuniformity in MRI data. | J G Sled, A P Zijdenbos, A C Evans | IEEE Trans Med Imaging | 1998 | 9617910 | Yes |
3470 | 1137 | 1137.0 | 40.36 | 40.4 | Neurotoxins that act on voltage-sensitive sodium channels in excitable membranes. | W A Catterall | Annu Rev Pharmacol Toxicol | 1980 | 6247957 | No |
3471 | 2274 | 1137.0 | 76.42 | 38.2 | Pharmaceuticals and personal care products in the environment: agents of subtle change? | C G Daughton, T A Ternes | Environ Health Perspect | 1999 | 10592150 | No |
3472 | 1137 | 1137.0 | 28.28 | 28.3 | Seed Germination and Dormancy. | J. D. Bewley | Plant Cell | 1997 | 12237375 | Yes |
3473 | 1137 | 1137.0 | 22.53 | 22.5 | Models, mechanisms and clinical evidence for cancer dormancy. | Julio A Aguirre-Ghiso | Nat Rev Cancer | 2007 | 17957189 | No |
3474 | 2273 | 1136.5 | 44.15 | 22.1 | Homeobox genes and axial patterning. | W McGinnis, R Krumlauf | Cell | 1992 | 1346368 | No |
3475 | 1136 | 1136.0 | 29.25 | 29.2 | Stereochemical criteria for polypeptides and proteins. V. Conformation of a system of three linked peptide units. | C M Venkatachalam | Biopolymers | 1968 | 5685102 | Yes |
3476 | 2272 | 1136.0 | 77.69 | 38.8 | Consensus methods for medical and health services research. | J Jones, D Hunter | BMJ | 1995 | 7640549 | No |
3477 | 3408 | 1136.0 | 120.76 | 40.3 | Neighborhoods and violent crime: a multilevel study of collective efficacy. | R J Sampson, S W Raudenbush, F Earls | Science | 1997 | 9252316 | Yes |
3478 | 1136 | 1136.0 | 16.66 | 16.7 | Biochemistry of dystrophic muscle. Mitochondrial succinate-tetrazolium reductase and adenosine triphosphatase. | R J Pennington | Biochem J | 1961 | 13734134 | Yes |
3479 | 1136 | 1136.0 | 40.16 | 40.2 | The pathobiology of vascular dementia. | Costantino Iadecola | Neuron | 2013 | 24267647 | No |
3480 | 2272 | 1136.0 | 83.87 | 41.9 | Long Noncoding RNAs in Cancer Pathways. | Adam M Schmitt, Howard Y Chang | Cancer Cell | 2016 | 27070700 | No |
3481 | 2271 | 1135.5 | 48.26 | 24.1 | Roles of CHOP/GADD153 in endoplasmic reticulum stress. | S Oyadomari, M Mori | Cell Death Differ | 2004 | 14685163 | No |
3482 | 2271 | 1135.5 | 50.79 | 25.4 | Modes of resistance to anti-angiogenic therapy. | Gabriele Bergers, Douglas Hanahan | Nat Rev Cancer | 2008 | 18650835 | No |
3483 | 1135 | 1135.0 | 20.37 | 20.4 | Shrinkage necrosis: a distinct mode of cellular death. | J F Kerr | J Pathol | 1971 | 4108566 | Yes |
3484 | 1135 | 1135.0 | 30.45 | 30.4 | What you see may not be what you get: a brief, nontechnical introduction to overfitting in regression-type models. | Michael A Babyak | Psychosom Med | 2004 | 15184705 | Yes |
3485 | 3405 | 1135.0 | 79.32 | 26.4 | Arabidopsis mesophyll protoplasts: a versatile cell system for transient gene expression analysis. | Sang-Dong Yoo, Young-Hee Cho, Jen Sheen | Nat Protoc | 2007 | 17585298 | Yes |
3486 | 3404 | 1134.7 | 93.2 | 31.1 | Cytochemical identification of monocytes and granulocytes. | L T Yam, C Y Li, W H Crosby | Am J Clin Pathol | 1971 | 5549896 | Yes |
3487 | 2269 | 1134.5 | 0.0 | 0.0 | Active transport of sodium as the source of electric current in the short-circuited isolated frog skin. | H H Ussing, K Zerahn | Acta Physiol Scand | 1951 | 14868510 | Yes |
3488 | 1134 | 1134.0 | 21.48 | 21.5 | Structure of chromatin. | R D Kornberg | Annu Rev Biochem | 1977 | 332067 | No |
3489 | 2268 | 1134.0 | 52.31 | 26.2 | The host defense of Drosophila melanogaster. | Bruno Lemaitre, Jules Hoffmann | Annu Rev Immunol | 2007 | 17201680 | No |
3490 | 1133 | 1133.0 | 32.23 | 32.2 | Cholesterol and the cell membrane. | P L Yeagle | Biochim Biophys Acta | 1985 | 3904832 | No |
3491 | 1133 | 1133.0 | 17.38 | 17.4 | Inherited Antithrombin Deficiency Causing Thrombophilia. | O Egeberg | Thromb Diath Haemorrh | 1965 | 14347873 | Yes |
3492 | 1133 | 1133.0 | 0.0 | 0.0 | The Stability of Broken Ends of Chromosomes in Zea Mays. | B McClintock | Genetics | 1941 | 17247004 | Yes |
3493 | 2265 | 1132.5 | 54.91 | 27.5 | Adipocytokines: mediators linking adipose tissue, inflammation and immunity. | Herbert Tilg, Alexander R Moschen | Nat Rev Immunol | 2006 | 16998510 | No |
3494 | 2264 | 1132.0 | 58.26 | 29.1 | Protein oxidation in aging, disease, and oxidative stress. | B S Berlett, E R Stadtman | J Biol Chem | 1997 | 9252331 | No |
3495 | 2263 | 1131.5 | 100.19 | 50.1 | Problems and proposals for recording gingivitis and plaque. | J Ainamo, I Bay | Int Dent J | 1975 | 1058834 | Yes |
3496 | 2263 | 1131.5 | 76.13 | 38.1 | Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. | A E Czeizel, I Dudás | N Engl J Med | 1992 | 1307234 | Yes |
3497 | 2263 | 1131.5 | 39.0 | 19.5 | A synthetic oscillatory network of transcriptional regulators. | M B Elowitz, S Leibler | Nature | 2000 | 10659856 | Yes |
3498 | 2263 | 1131.5 | 65.4 | 32.7 | Are the dorsal and ventral hippocampus functionally distinct structures? | Michael S Fanselow, Hong-Wei Dong | Neuron | 2010 | 20152109 | No |
3499 | 2262 | 1131.0 | 59.48 | 29.7 | Fitness effects on the cognitive function of older adults: a meta-analytic study. | Stanley Colcombe, Arthur F Kramer | Psychol Sci | 2003 | 12661673 | Yes |
3500 | 1131 | 1131.0 | 0.0 | 0.0 | pA, a new scale for the measurement of drug antagonism. | H O Schild | Br J Pharmacol Chemother | 1947 | 20258355 | Yes |
3501 | 2261 | 1130.5 | 46.31 | 23.2 | Genomic control for association studies. | B Devlin, K Roeder | Biometrics | 1999 | 11315092 | Yes |
3502 | 1130 | 1130.0 | 24.99 | 25.0 | Possible role of flanking nucleotides in recognition of the AUG initiator codon by eukaryotic ribosomes. | M Kozak | Nucleic Acids Res | 1981 | 7301588 | Yes |
3503 | 1130 | 1130.0 | 23.93 | 23.9 | Fluorescence spectroscopy of single biomolecules. | S Weiss | Science | 1999 | 10073925 | No |
3504 | 1130 | 1130.0 | 36.1 | 36.1 | Predictors of postpartum depression: an update. | C T Beck | Nurs Res | 2001 | 11570712 | Yes |
3505 | 1130 | 1130.0 | 35.0 | 35.0 | Polybrominated diphenyl ethers in the environment and in people: a meta-analysis of concentrations. | Ronald A Hites | Environ Sci Technol | 2004 | 14998004 | Yes |
3506 | 3390 | 1130.0 | 77.75 | 25.9 | Obesity induces a phenotypic switch in adipose tissue macrophage polarization. | Carey N Lumeng, Jennifer L Bodzin, Alan R Saltiel | J Clin Invest | 2007 | 17200717 | Yes |
3507 | 2259 | 1129.5 | 116.94 | 58.5 | The Neck Disability Index: a study of reliability and validity. | H Vernon, S Mior | J Manipulative Physiol Ther | 1991 | 1834753 | Yes |
3508 | 2259 | 1129.5 | 49.05 | 24.5 | Regeneration beyond the glial scar. | Jerry Silver, Jared H Miller | Nat Rev Neurosci | 2004 | 14735117 | No |
3509 | 2259 | 1129.5 | 53.04 | 26.5 | Reducing the dimensionality of data with neural networks. | G E Hinton, R R Salakhutdinov | Science | 2006 | 16873662 | Yes |
3510 | 3387 | 1129.0 | 90.65 | 30.2 | Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. | R Schreck, P Rieber, P A Baeuerle | EMBO J | 1991 | 2065663 | Yes |
3511 | 1129 | 1129.0 | 52.21 | 52.2 | Resilience in the face of adversity. Protective factors and resistance to psychiatric disorder. | M Rutter | Br J Psychiatry | 1985 | 3830321 | Yes |
3512 | 1129 | 1129.0 | 28.5 | 28.5 | Intestinal epithelial cell surface membrane glycoprotein synthesis. I. An indicator of cellular differentiation. | M M Weiser | J Biol Chem | 1973 | 4698230 | Yes |
3513 | 1129 | 1129.0 | 26.03 | 26.0 | Allelic discrimination using fluorogenic probes and the 5' nuclease assay. | K J Livak | Genet Anal | 1999 | 10084106 | Yes |
3514 | 4515 | 1128.8 | 108.24 | 27.1 | C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. | P M Ridker, C H Hennekens, J E Buring, N Rifai | N Engl J Med | 2000 | 10733371 | Yes |
3515 | 1128 | 1128.0 | 68.18 | 68.2 | Cytoprotection by prostaglandins. | A Robert | Gastroenterology | 1979 | 38173 | Yes |
3516 | 1128 | 1128.0 | 23.69 | 23.7 | Mutator phenotype may be required for multistage carcinogenesis. | L A Loeb | Cancer Res | 1991 | 2039987 | No |
3517 | 1128 | 1128.0 | 29.57 | 29.6 | Mechanisms of lipid peroxide formation in animal tissues. | E D Wills | Biochem J | 1966 | 5964963 | Yes |
3518 | 1128 | 1128.0 | 42.7 | 42.7 | On the regulation and control of fibrinolysis. Edward Kowalski Memorial Lecture. | D Collen | Thromb Haemost | 1980 | 6450468 | No |
3519 | 2256 | 1128.0 | 54.99 | 27.5 | The protective effects of estrogen on the cardiovascular system. | M E Mendelsohn, R H Karas | N Engl J Med | 1999 | 10362825 | No |
3520 | 1128 | 1128.0 | 20.18 | 20.2 | The development of neural stem cells. | S Temple | Nature | 2001 | 11689956 | No |
3521 | 1128 | 1128.0 | 20.36 | 20.4 | DNA methylation in cancer: too much, but also too little. | Melanie Ehrlich | Oncogene | 2002 | 12154403 | No |
3522 | 1128 | 1128.0 | 0.0 | 0.0 | Micromethods for the study of proteins and antibodies. I. Procedure and general applications of hemagglutination and hemagglutination-inhibition reactions with tannic acid and protein-treated red blood cells. | A B Stavitsky | J Immunol | 1954 | 13163409 | Yes |
3523 | 1128 | 1128.0 | 23.9 | 23.9 | Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology. | Michael Forgac | Nat Rev Mol Cell Biol | 2007 | 17912264 | No |
3524 | 1128 | 1128.0 | 26.88 | 26.9 | ImageJ for microscopy. | Tony J Collins | Biotechniques | 2007 | 17936939 | No |
3525 | 3383 | 1127.7 | 93.56 | 31.2 | Spirometric reference values from a sample of the general U.S. population. | J L Hankinson, J R Odencrantz, K B Fedan | Am J Respir Crit Care Med | 1999 | 9872837 | Yes |
3526 | 1127 | 1127.0 | 22.09 | 22.1 | Regulation of transcription by MAP kinase cascades. | R Treisman | Curr Opin Cell Biol | 1996 | 8791420 | No |
3527 | 2254 | 1127.0 | 90.97 | 45.5 | AKT/PKB Signaling: Navigating the Network. | Brendan D Manning, Alex Toker | Cell | 2017 | 28431241 | No |
3528 | 4506 | 1126.5 | 108.29 | 27.1 | CHARMM-GUI: a web-based graphical user interface for CHARMM. | Sunhwan Jo, Taehoon Kim, Vidyashankara G Iyer, Wonpil Im | J Comput Chem | 2008 | 18351591 | No |
3529 | 4505 | 1126.2 | 103.8 | 25.9 | SCOP: a structural classification of proteins database for the investigation of sequences and structures. | A G Murzin, S E Brenner, T Hubbard, C Chothia | J Mol Biol | 1995 | 7723011 | Yes |
3530 | 1126 | 1126.0 | 33.12 | 33.1 | Animal mitochondrial DNA: structure and evolution. | D R Wolstenholme | Int Rev Cytol | 1992 | 1452431 | No |
3531 | 2252 | 1126.0 | 36.42 | 18.2 | Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases. | L M Siegel, K J Monty | Biochim Biophys Acta | 1966 | 5329026 | Yes |
3532 | 1126 | 1126.0 | 72.2 | 72.2 | A network theory of mental disorders. | Denny Borsboom | World Psychiatry | 2017 | 28127906 | Yes |
3533 | 1125 | 1125.0 | 23.74 | 23.7 | Molecular cloning and expression of glycogen synthase kinase-3/factor A. | J R Woodgett | EMBO J | 1990 | 2164470 | Yes |
3534 | 2250 | 1125.0 | 50.0 | 25.0 | Synaptic activity and the construction of cortical circuits. | L C Katz, C J Shatz | Science | 1996 | 8895456 | No |
3535 | 1125 | 1125.0 | 26.29 | 26.3 | Differential projections of the infralimbic and prelimbic cortex in the rat. | Robert P Vertes | Synapse | 2004 | 14579424 | Yes |
3536 | 2250 | 1125.0 | 92.28 | 46.1 | The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities. | Samuel Genheden, Ulf Ryde | Expert Opin Drug Discov | 2015 | 25835573 | No |
3537 | 2249 | 1124.5 | 59.26 | 29.6 | Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. | R A Ignotz, J Massagué | J Biol Chem | 1986 | 3456347 | Yes |
3538 | 1124 | 1124.0 | 57.02 | 57.0 | Osseointegration and its experimental background. | P I Brånemark | J Prosthet Dent | 1983 | 6352924 | No |
3539 | 1124 | 1124.0 | 34.35 | 34.4 | Inferring microstructural features and the physiological state of tissues from diffusion-weighted images. | P J Basser | NMR Biomed | 1995 | 8739270 | No |
3540 | 1124 | 1124.0 | 29.16 | 29.2 | Bile acids: regulation of synthesis. | John Y L Chiang | J Lipid Res | 2009 | 19346330 | No |
3541 | 2247 | 1123.5 | 92.41 | 46.2 | Using Effect Size-or Why the P Value Is Not Enough. | Gail M Sullivan, Richard Feinn | J Grad Med Educ | 2012 | 23997866 | Yes |
3542 | 11234 | 1123.4 | 253.53 | 25.4 | Scalable molecular dynamics with NAMD. | James C Phillips, Rosemary Braun, Wei Wang, James Gumbart, Emad Tajkhorshid, Elizabeth Villa, Christophe Chipot, Robert D Skeel, Laxmikant Kalé, Klaus Schulten | J Comput Chem | 2005 | 16222654 | Yes |
3543 | 1123 | 1123.0 | 49.4 | 49.4 | Sixth gaddum memorial lecture, National Institute for Medical Research, Mill Hill, January 1977. Presynaptic receptors and their role in the regulation of transmitter release. | S Z Langer | Br J Pharmacol | 1977 | 20190 | No |
3544 | 1123 | 1123.0 | 39.79 | 39.8 | Epidemiological synergy. Interrelationships between human immunodeficiency virus infection and other sexually transmitted diseases. | J N Wasserheit | Sex Transm Dis | 1992 | 1595015 | No |
3545 | 1123 | 1123.0 | 42.61 | 42.6 | Radioimmunoassay: a method for human chorionic gonadotropin and human luteinizing hormone. | A R Midgley | Endocrinology | 1966 | 5950482 | Yes |
3546 | 3369 | 1123.0 | 159.66 | 53.2 | Development of an upper extremity outcome measure: the DASH (disabilities of the arm, shoulder and hand) [corrected]. The Upper Extremity Collaborative Group (UECG) | P L Hudak, P C Amadio, C Bombardier | Am J Ind Med | 1996 | 8773720 | Yes |
3547 | 1123 | 1123.0 | 36.8 | 36.8 | Socioeconomic disadvantage and child development. | V C McLoyd | Am Psychol | 1998 | 9491747 | No |
3548 | 2246 | 1123.0 | 47.92 | 24.0 | Finding and evaluating community structure in networks. | M E J Newman, M Girvan | Phys Rev E Stat Nonlin Soft Matter Phys | 2004 | 14995526 | Yes |
3549 | 2245 | 1122.5 | 45.13 | 22.6 | RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. | M B Shapiro, P Senapathy | Nucleic Acids Res | 1987 | 3658675 | Yes |
3550 | 1122 | 1122.0 | 34.57 | 34.6 | Prostate specific antigen: a critical assessment of the most useful tumor marker for adenocarcinoma of the prostate. | J E Oesterling | J Urol | 1991 | 1707989 | No |
3551 | 1122 | 1122.0 | 29.81 | 29.8 | The chromosomal basis of human neoplasia. | J J Yunis | Science | 1983 | 6336310 | Yes |
3552 | 1122 | 1122.0 | 32.85 | 32.9 | Cell surface interactions with extracellular materials. | K M Yamada | Annu Rev Biochem | 1983 | 6351729 | No |
3553 | 1122 | 1122.0 | 23.36 | 23.4 | ALSCRIPT: a tool to format multiple sequence alignments. | G J Barton | Protein Eng | 1993 | 8433969 | Yes |
3554 | 1122 | 1122.0 | 20.82 | 20.8 | The ubiquitin-proteasome pathway: on protein death and cell life. | A Ciechanover | EMBO J | 1998 | 9857172 | No |
3555 | 1122 | 1122.0 | 37.68 | 37.7 | A review of psychological risk factors in back and neck pain. | S J Linton | Spine (Phila Pa 1976) | 2000 | 10788861 | No |
3556 | 1122 | 1122.0 | 24.75 | 24.8 | Lithium batteries and cathode materials. | M Stanley Whittingham | Chem Rev | 2004 | 15669156 | Yes |
3557 | 2243 | 1121.5 | 58.9 | 29.4 | Oxidative stress, caloric restriction, and aging. | R S Sohal, R Weindruch | Science | 1996 | 8658196 | No |
3558 | 1121 | 1121.0 | 28.71 | 28.7 | Linkage strategies for genetically complex traits. I. Multilocus models. | N Risch | Am J Hum Genet | 1990 | 2301392 | Yes |
3559 | 2242 | 1121.0 | 63.43 | 31.7 | Strategies in the design of nanoparticles for therapeutic applications. | Robby A Petros, Joseph M DeSimone | Nat Rev Drug Discov | 2010 | 20616808 | No |
3560 | 4483 | 1120.8 | 144.52 | 36.1 | The cholinergic hypothesis of geriatric memory dysfunction. | R T Bartus, R L Dean, B Beer, A S Lippa | Science | 1982 | 7046051 | No |
3561 | 1120 | 1120.0 | 52.7 | 52.7 | Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase. | Y Kono | Arch Biochem Biophys | 1978 | 24422 | Yes |
3562 | 1120 | 1120.0 | 30.04 | 30.0 | Comprehensive observational assessment: Ia. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse. | S Irwin | Psychopharmacologia | 1968 | 5679627 | Yes |
3563 | 2239 | 1119.5 | 48.61 | 24.3 | Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. | Daniel J Hicklin, Lee M Ellis | J Clin Oncol | 2005 | 15585754 | No |
3564 | 1119 | 1119.0 | 43.89 | 43.9 | A simple method for determination of serum catalase activity and revision of reference range. | L Góth | Clin Chim Acta | 1991 | 2029780 | Yes |
3565 | 1119 | 1119.0 | 34.62 | 34.6 | Protein damage and degradation by oxygen radicals. I. general aspects. | K J Davies | J Biol Chem | 1987 | 3036875 | Yes |
3566 | 1119 | 1119.0 | 37.27 | 37.3 | Chemoprevention of cancer. | L W Wattenberg | Cancer Res | 1985 | 3880665 | No |
3567 | 2238 | 1119.0 | 48.76 | 24.4 | Prediction of protein secondary structure at better than 70% accuracy. | B Rost, C Sander | J Mol Biol | 1993 | 8345525 | Yes |
3568 | 5595 | 1119.0 | 110.37 | 22.1 | Electrostatics of nanosystems: application to microtubules and the ribosome. | N A Baker, D Sept, S Joseph, M J Holst, J A McCammon | Proc Natl Acad Sci U S A | 2001 | 11517324 | Yes |
3569 | 1119 | 1119.0 | 27.7 | 27.7 | Pathogenesis of osteoporosis: concepts, conflicts, and prospects. | Lawrence G Raisz | J Clin Invest | 2005 | 16322775 | No |
3570 | 1119 | 1119.0 | 38.57 | 38.6 | Epidemiology of heart failure. | Véronique L Roger | Circ Res | 2013 | 23989710 | No |
3571 | 6714 | 1119.0 | 249.25 | 41.5 | StringTie enables improved reconstruction of a transcriptome from RNA-seq reads. | Mihaela Pertea, Geo M Pertea, Corina M Antonescu, Tsung-Cheng Chang, Joshua T Mendell, Steven L Salzberg | Nat Biotechnol | 2015 | 25690850 | Yes |
3572 | 6710 | 1118.3 | 175.46 | 29.2 | Prediction of coronary heart disease using risk factor categories. | P W Wilson, R B D'Agostino, D Levy, A M Belanger, H Silbershatz, W B Kannel | Circulation | 1998 | 9603539 | Yes |
3573 | 1118 | 1118.0 | 54.91 | 54.9 | The sociological study of stress. | L I Pearlin | J Health Soc Behav | 1989 | 2674272 | No |
3574 | 1118 | 1118.0 | 33.1 | 33.1 | Plasmid complements of Streptococcus lactis NCDO 712 and other lactic streptococci after protoplast-induced curing. | M J Gasson | J Bacteriol | 1983 | 6403500 | Yes |
3575 | 1118 | 1118.0 | 26.7 | 26.7 | Molecular drive: a cohesive mode of species evolution. | G Dover | Nature | 1982 | 7110332 | Yes |
3576 | 2236 | 1118.0 | 44.9 | 22.4 | A survey of telomerase activity in human cancer. | J W Shay, S Bacchetti | Eur J Cancer | 1997 | 9282118 | No |
3577 | 1118 | 1118.0 | 23.75 | 23.8 | Complement. Second of two parts. | M J Walport | N Engl J Med | 2001 | 11297706 | No |
3578 | 2236 | 1118.0 | 58.72 | 29.4 | Localized surface plasmon resonance spectroscopy and sensing. | Katherine A Willets, Richard P Van Duyne | Annu Rev Phys Chem | 2007 | 17067281 | No |
3579 | 1118 | 1118.0 | 22.81 | 22.8 | Membrane recognition by phospholipid-binding domains. | Mark A Lemmon | Nat Rev Mol Cell Biol | 2008 | 18216767 | No |
3580 | 4470 | 1117.5 | 192.82 | 48.2 | Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator. | Jack Bowden, George Davey Smith, Philip C Haycock, Stephen Burgess | Genet Epidemiol | 2016 | 27061298 | Yes |
3581 | 11172 | 1117.2 | 368.14 | 36.8 | The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. | N K Aaronson, S Ahmedzai, B Bergman, M Bullinger, A Cull, N J Duez, A Filiberti, H Flechtner, S B Fleishman, J C de Haes | J Natl Cancer Inst | 1993 | 8433390 | Yes |
3582 | 4468 | 1117.0 | 34.15 | 8.5 | The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. | P J Randle, P B Garland, C N Hales, E A Newsholme | Lancet | 1963 | 13990765 | Yes |
3583 | 2233 | 1116.5 | 66.59 | 33.3 | Reactive oxygen species, cellular redox systems, and apoptosis. | Magdalena L Circu, Tak Yee Aw | Free Radic Biol Med | 2010 | 20045723 | No |
3584 | 1116 | 1116.0 | 38.97 | 39.0 | Spin trapping: ESR parameters of spin adducts. | G R Buettner | Free Radic Biol Med | 1987 | 2826304 | No |
3585 | 1116 | 1116.0 | 19.96 | 20.0 | Cell lines derived from late embryonic stages of Drosophila melanogaster. | I Schneider | J Embryol Exp Morphol | 1972 | 4625067 | Yes |
3586 | 1116 | 1116.0 | 25.86 | 25.9 | Solid-state nanopores. | Cees Dekker | Nat Nanotechnol | 2007 | 18654264 | No |
3587 | 1116 | 1116.0 | 24.26 | 24.3 | Personal genomes: The case of the missing heritability. | Brendan Maher | Nature | 2008 | 18987709 | No |
3588 | 2231 | 1115.5 | 52.13 | 26.1 | Cellular uptake of the tat protein from human immunodeficiency virus. | A D Frankel, C O Pabo | Cell | 1988 | 2849510 | Yes |
3589 | 1115 | 1115.0 | 27.88 | 27.9 | Sex-hormone-binding globulin. | D C Anderson | Clin Endocrinol (Oxf) | 1974 | 4134992 | No |
3590 | 1115 | 1115.0 | 13.31 | 13.3 | Studies on histones. 7. Preparative methods for histone fractions from calf thymus. | E W Johns | Biochem J | 1964 | 5840387 | Yes |
3591 | 2229 | 1114.5 | 50.01 | 25.0 | A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. | J N Cohn, G Tognoni | N Engl J Med | 2001 | 11759645 | Yes |
3592 | 1114 | 1114.0 | 28.36 | 28.4 | Unequal treatment: confronting racial and ethnic disparities in health care. | Alan Nelson | J Natl Med Assoc | 2002 | 12152921 | No |
3593 | 2227 | 1113.5 | 71.57 | 35.8 | Wine, alcohol, platelets, and the French paradox for coronary heart disease. | S Renaud, M de Lorgeril | Lancet | 1992 | 1351198 | Yes |
3594 | 1113 | 1113.0 | 75.94 | 75.9 | Root canal anatomy of the human permanent teeth. | F J Vertucci | Oral Surg Oral Med Oral Pathol | 1984 | 6595621 | Yes |
3595 | 2226 | 1113.0 | 45.48 | 22.7 | The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000. | A Bairoch, R Apweiler | Nucleic Acids Res | 2000 | 10592178 | Yes |
3596 | 1113 | 1113.0 | 24.72 | 24.7 | Current concepts of the pathogenesis of the acute coronary syndromes. | P Libby | Circulation | 2001 | 11457759 | No |
3597 | 2226 | 1113.0 | 54.32 | 27.2 | Quorum sensing: cell-to-cell communication in bacteria. | Christopher M Waters, Bonnie L Bassler | Annu Rev Cell Dev Biol | 2005 | 16212498 | No |
3598 | 1113 | 1113.0 | 26.45 | 26.4 | Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. | Thomas A Wynn | J Clin Invest | 2007 | 17332879 | No |
3599 | 1113 | 1113.0 | 24.58 | 24.6 | The impact of next-generation sequencing technology on genetics. | Elaine R Mardis | Trends Genet | 2008 | 18262675 | No |
3600 | 4450 | 1112.5 | 116.62 | 29.2 | Prevalence and trends in obesity among US adults, 1999-2000. | Katherine M Flegal, Margaret D Carroll, Cynthia L Ogden, Clifford L Johnson | JAMA | 2002 | 12365955 | Yes |
3601 | 2225 | 1112.5 | 64.74 | 32.4 | Chronic hepatitis B: update 2009. | Anna S F Lok, Brian J McMahon | Hepatology | 2009 | 19714720 | Yes |
3602 | 1112 | 1112.0 | 57.05 | 57.0 | The tension-stress effect on the genesis and growth of tissues: Part II. The influence of the rate and frequency of distraction. | G A Ilizarov | Clin Orthop Relat Res | 1989 | 2912628 | Yes |
3603 | 1112 | 1112.0 | 25.6 | 25.6 | Large Amplitude Elastic Motions in Proteins from a Single-Parameter, Atomic Analysis. | M M Tirion | Phys Rev Lett | 1996 | 10063201 | Yes |
3604 | 1112 | 1112.0 | 23.45 | 23.4 | Twilight zone of protein sequence alignments. | B Rost | Protein Eng | 1999 | 10195279 | Yes |
3605 | 1112 | 1112.0 | 25.43 | 25.4 | The prefrontal cortex--an update: time is of the essence. | J M Fuster | Neuron | 2001 | 11394996 | No |
3606 | 2224 | 1112.0 | 32.38 | 16.2 | Microdroplet Assay Of Human Serum Cytotoxins. | P I Terasaki, J D Mcclelland | Nature | 1964 | 14248725 | Yes |
3607 | 1112 | 1112.0 | 29.23 | 29.2 | Abiotic stress, the field environment and stress combination. | Ron Mittler | Trends Plant Sci | 2006 | 16359910 | No |
3608 | 2224 | 1112.0 | 100.96 | 50.5 | Organic Photoredox Catalysis. | Nathan A Romero, David A Nicewicz | Chem Rev | 2016 | 27285582 | Yes |
3609 | 3335 | 1111.7 | 88.85 | 29.6 | Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation. | Davis J McCarthy, Yunshun Chen, Gordon K Smyth | Nucleic Acids Res | 2012 | 22287627 | Yes |
3610 | 2222 | 1111.0 | 69.64 | 34.8 | Excitatory amino acid transmitters. | J C Watkins, R H Evans | Annu Rev Pharmacol Toxicol | 1981 | 6112965 | No |
3611 | 1111 | 1111.0 | 0.0 | 0.0 | A cytoarchitectonic atlas of the spinal cord in the cat. | B Rexed | J Comp Neurol | 1954 | 13163236 | Yes |
3612 | 1110 | 1110.0 | 59.58 | 59.6 | The stabilizing system of the spine. Part I. Function, dysfunction, adaptation, and enhancement. | M M Panjabi | J Spinal Disord | 1992 | 1490034 | Yes |
3613 | 2220 | 1110.0 | 50.04 | 25.0 | Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms. | R J Britten, D E Kohne | Science | 1968 | 4874239 | Yes |
3614 | 1110 | 1110.0 | 27.58 | 27.6 | The Trk family of neurotrophin receptors. | M Barbacid | J Neurobiol | 1994 | 7852993 | No |
3615 | 1110 | 1110.0 | 44.47 | 44.5 | The anatomy of stages of change. | A Bandura | Am J Health Promot | 1997 | 10170438 | No |
3616 | 1110 | 1110.0 | 22.35 | 22.4 | Osmotic stress signaling and osmoadaptation in yeasts. | Stefan Hohmann | Microbiol Mol Biol Rev | 2002 | 12040128 | No |
3617 | 1110 | 1110.0 | 30.14 | 30.1 | Principles of c-di-GMP signalling in bacteria. | Regine Hengge | Nat Rev Microbiol | 2009 | 19287449 | No |
3618 | 2219 | 1109.5 | 52.13 | 26.1 | T antigen is bound to a host protein in SV40-transformed cells. | D P Lane, L V Crawford | Nature | 1979 | 218111 | Yes |
3619 | 5547 | 1109.4 | 150.21 | 30.0 | Biodiversity hotspots for conservation priorities. | N Myers, R A Mittermeier, C G Mittermeier, G A da Fonseca, J Kent | Nature | 2000 | 10706275 | Yes |
3620 | 1109 | 1109.0 | 23.78 | 23.8 | Toward self-organization and complex matter. | Jean-Marie Lehn | Science | 2002 | 11923524 | Yes |
3621 | 1109 | 1109.0 | 20.92 | 20.9 | Focal adhesion kinase: the first ten years. | J Thomas Parsons | J Cell Sci | 2003 | 12640026 | No |
3622 | 1109 | 1109.0 | 32.95 | 33.0 | Social support and patient adherence to medical treatment: a meta-analysis. | M Robin DiMatteo | Health Psychol | 2004 | 15008666 | Yes |
3623 | 1109 | 1109.0 | 45.5 | 45.5 | A comprehensive review on metabolic syndrome. | Jaspinder Kaur | Cardiol Res Pract | 2014 | 24711954 | No |
3624 | 3326 | 1108.7 | 86.37 | 28.8 | Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. | M K Parmar, V Torri, L Stewart | Stat Med | 1998 | 9921604 | Yes |
3625 | 2217 | 1108.5 | 57.13 | 28.6 | A rating scale for extrapyramidal side effects. | G M Simpson, J W Angus | Acta Psychiatr Scand Suppl | 1970 | 4917967 | Yes |
3626 | 2217 | 1108.5 | 54.03 | 27.0 | Sulforhodamine B colorimetric assay for cytotoxicity screening. | Vanicha Vichai, Kanyawim Kirtikara | Nat Protoc | 2006 | 17406391 | Yes |
3627 | 1108 | 1108.0 | 22.98 | 23.0 | Phenotypic plasticity and the epigenetics of human disease. | Andrew P Feinberg | Nature | 2007 | 17522677 | No |
3628 | 3323 | 1107.7 | 118.88 | 39.6 | Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. | P S Walsh, D A Metzger, R Higuchi | Biotechniques | 1991 | 1867860 | Yes |
3629 | 3323 | 1107.7 | 69.49 | 23.2 | 5-fluorouracil: mechanisms of action and clinical strategies. | Daniel B Longley, D Paul Harkin, Patrick G Johnston | Nat Rev Cancer | 2003 | 12724731 | No |
3630 | 2215 | 1107.5 | 116.03 | 58.0 | New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer. | Anushka Dongre, Robert A Weinberg | Nat Rev Mol Cell Biol | 2019 | 30459476 | No |
3631 | 1107 | 1107.0 | 23.22 | 23.2 | A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor. | J Milbrandt | Science | 1987 | 3672127 | Yes |
3632 | 1107 | 1107.0 | 40.01 | 40.0 | Methods for dealing with reaction time outliers. | R Ratcliff | Psychol Bull | 1993 | 8272468 | Yes |
3633 | 1107 | 1107.0 | 26.51 | 26.5 | Cells in stress: transcriptional activation of heat shock genes. | R I Morimoto | Science | 1993 | 8451637 | No |
3634 | 1107 | 1107.0 | 28.16 | 28.2 | Glutathione and its role in cellular functions. | H Sies | Free Radic Biol Med | 1999 | 10569624 | No |
3635 | 1107 | 1107.0 | 29.05 | 29.1 | Philosophical conceptions of the self: implications for cognitive science. | I Gallagher | Trends Cogn Sci | 2000 | 10637618 | Yes |
3636 | 1107 | 1107.0 | 28.94 | 28.9 | Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity. | F P Guengerich | Chem Res Toxicol | 2001 | 11409933 | No |
3637 | 3319 | 1106.3 | 107.75 | 35.9 | Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides. | M Hamberg, J Svensson, B Samuelsson | Proc Natl Acad Sci U S A | 1975 | 1059088 | Yes |
3638 | 1106 | 1106.0 | 22.24 | 22.2 | Primary response genes induced by growth factors and tumor promoters. | H R Herschman | Annu Rev Biochem | 1991 | 1883198 | No |
3639 | 1106 | 1106.0 | 21.77 | 21.8 | Cytokine receptor signalling. | J N Ihle | Nature | 1995 | 7566171 | No |
3640 | 1106 | 1106.0 | 0.0 | 0.0 | The stereotaxic method and radiosurgery of the brain. | L Leksell | Acta Chir Scand | 1951 | 14914373 | Yes |
3641 | 1106 | 1106.0 | 34.45 | 34.5 | Lumbar disc disorders and low-back pain: socioeconomic factors and consequences. | Jeffrey N Katz | J Bone Joint Surg Am | 2006 | 16595438 | No |
3642 | 1106 | 1106.0 | 50.08 | 50.1 | Cystic fibrosis. | J Stuart Elborn | Lancet | 2016 | 27140670 | No |
3643 | 3312 | 1104.0 | 130.5 | 43.5 | Concurrent and predictive validity of a self-reported measure of medication adherence. | D E Morisky, L W Green, D M Levine | Med Care | 1986 | 3945130 | Yes |
3644 | 2208 | 1104.0 | 35.11 | 17.6 | Construction of phylogenetic trees. | W M Fitch, E Margoliash | Science | 1967 | 5334057 | No |
3645 | 1104 | 1104.0 | 21.18 | 21.2 | Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. | A S Baldwin | J Clin Invest | 2001 | 11160144 | No |
3646 | 1104 | 1104.0 | 27.85 | 27.9 | Redefining oxidative stress. | Dean P Jones | Antioxid Redox Signal | 2006 | 16987039 | No |
3647 | 1104 | 1104.0 | 0.0 | 0.0 | Immunogenetic Consequences Of Vascular Anastomoses Between Bovine Twins. | R D Owen | Science | 1945 | 17755278 | Yes |
3648 | 2208 | 1104.0 | 61.41 | 30.7 | Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. | Amit Etkin, Tor D Wager | Am J Psychiatry | 2007 | 17898336 | Yes |
3649 | 1104 | 1104.0 | 43.01 | 43.0 | Intention-to-treat concept: A review. | Sandeep K Gupta | Perspect Clin Res | 2011 | 21897887 | Yes |
3650 | 2208 | 1104.0 | 116.94 | 58.5 | Sexually transmitted diseases treatment guidelines, 2015. | Kimberly A Workowski, Gail A Bolan | MMWR Recomm Rep | 2015 | 26042815 | No |
3651 | 2207 | 1103.5 | 63.32 | 31.7 | Accurate and robust brain image alignment using boundary-based registration. | Douglas N Greve, Bruce Fischl | Neuroimage | 2009 | 19573611 | Yes |
3652 | 1103 | 1103.0 | 33.74 | 33.7 | Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. | D L Coleman | Diabetologia | 1978 | 350680 | No |
3653 | 1103 | 1103.0 | 25.5 | 25.5 | BIONJ: an improved version of the NJ algorithm based on a simple model of sequence data. | O Gascuel | Mol Biol Evol | 1997 | 9254330 | Yes |
3654 | 1103 | 1103.0 | 27.8 | 27.8 | Epidemiology of urinary tract infections: incidence, morbidity, and economic costs. | Betsy Foxman | Am J Med | 2002 | 12113866 | No |
3655 | 1103 | 1103.0 | 29.07 | 29.1 | Neuronal gamma-band synchronization as a fundamental process in cortical computation. | Pascal Fries | Annu Rev Neurosci | 2009 | 19400723 | No |
3656 | 1103 | 1103.0 | 43.83 | 43.8 | Likert scales, levels of measurement and the "laws" of statistics. | Geoff Norman | Adv Health Sci Educ Theory Pract | 2010 | 20146096 | Yes |
3657 | 4411 | 1102.8 | 146.28 | 36.6 | Prevalence and trends in obesity among US adults, 1999-2008. | Katherine M Flegal, Margaret D Carroll, Cynthia L Ogden, Lester R Curtin | JAMA | 2010 | 20071471 | Yes |
3658 | 2205 | 1102.5 | 65.87 | 32.9 | Mental rotation of three-dimensional objects. | R N Shepard, J Metzler | Science | 1971 | 5540314 | Yes |
3659 | 2205 | 1102.5 | 44.09 | 22.0 | Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm. | P E Wright, H J Dyson | J Mol Biol | 1999 | 10550212 | No |
3660 | 2205 | 1102.5 | 27.11 | 13.6 | Demonstration Of Tumor-Specific Antigens In Human Colonic Carcinomata By Immunological Tolerance And Absorption Techniques. | P Gold, S O Freedman | J Exp Med | 1965 | 14270243 | Yes |
3661 | 1102 | 1102.0 | 24.78 | 24.8 | Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes: a proposal for a synonymous codon choice that is optimal for the E. coli translational system. | T Ikemura | J Mol Biol | 1981 | 6175758 | Yes |
3662 | 1102 | 1102.0 | 19.91 | 19.9 | Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. | R A Frye | Biochem Biophys Res Commun | 2000 | 10873683 | Yes |
3663 | 1102 | 1102.0 | 0.0 | 0.0 | Quantitative Determination of Carbohydrates With Dreywood's Anthrone Reagent. | D L Morris | Science | 1948 | 17814729 | Yes |
3664 | 2203 | 1101.5 | 0.0 | 0.0 | Cortisone in ulcerative colitis; final report on a therapeutic trial. | S C Truelove, L J Witts | Br Med J | 1955 | 13260656 | Yes |
3665 | 2203 | 1101.5 | 0.0 | 0.0 | Localization of antigen in tissue cells; improvements in a method for the detection of antigen by means of fluorescent antibody. | A H Coons, M H Kaplan | J Exp Med | 1950 | 15395569 | Yes |
3666 | 2203 | 1101.5 | 71.32 | 35.7 | Prostaglandins and inflammation. | Emanuela Ricciotti, Garret A FitzGerald | Arterioscler Thromb Vasc Biol | 2011 | 21508345 | No |
3667 | 2203 | 1101.5 | 227.29 | 113.6 | Mental Health and the Covid-19 Pandemic. | Betty Pfefferbaum, Carol S North | N Engl J Med | 2020 | 32283003 | Yes |
3668 | 1101 | 1101.0 | 30.43 | 30.4 | Transport of molecules in the tumor interstitium: a review. | R K Jain | Cancer Res | 1987 | 3555767 | No |
3669 | 1101 | 1101.0 | 27.39 | 27.4 | A kinetic photometric method for serum gamma-glutamyl transpeptidase. | G Szasz | Clin Chem | 1969 | 5773262 | Yes |
3670 | 1101 | 1101.0 | 24.47 | 24.5 | The molecular biology of leukocyte chemoattractant receptors. | P M Murphy | Annu Rev Immunol | 1994 | 8011292 | No |
3671 | 1101 | 1101.0 | 29.48 | 29.5 | Interval estimation for the difference between independent proportions: comparison of eleven methods. | R G Newcombe | Stat Med | 1998 | 9595617 | Yes |
3672 | 1101 | 1101.0 | 20.24 | 20.2 | Chronic myeloid leukemia. | C L Sawyers | N Engl J Med | 1999 | 10219069 | No |
3673 | 1101 | 1101.0 | 26.11 | 26.1 | Quantification of beta-sheet amyloid fibril structures with thioflavin T. | H LeVine | Methods Enzymol | 1999 | 10507030 | Yes |
3674 | 1101 | 1101.0 | 0.0 | 0.0 | Asymptomatic infections of the urinary tract. | E H Kass | Trans Assoc Am Physicians | 1956 | 13380946 | Yes |
3675 | 1101 | 1101.0 | 31.24 | 31.2 | Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy. | Gregg L Semenza | Trends Pharmacol Sci | 2012 | 22398146 | No |
3676 | 1101 | 1101.0 | 55.14 | 55.1 | Statistical notes for clinical researchers: assessing normal distribution (2) using skewness and kurtosis. | Hae-Young Kim | Restor Dent Endod | 2013 | 23495371 | Yes |
3677 | 6601 | 1100.2 | 203.62 | 33.9 | Prodigal: prokaryotic gene recognition and translation initiation site identification. | Doug Hyatt, Gwo-Liang Chen, Philip F Locascio, Miriam L Land, Frank W Larimer, Loren J Hauser | BMC Bioinformatics | 2010 | 20211023 | Yes |
3678 | 1100 | 1100.0 | 39.64 | 39.6 | Attention, similarity, and the identification-categorization relationship. | R M Nosofsky | J Exp Psychol Gen | 1986 | 2937873 | Yes |
3679 | 1100 | 1100.0 | 27.71 | 27.7 | Two distinct classes of carbohydrate-recognition domains in animal lectins. | K Drickamer | J Biol Chem | 1988 | 3290208 | No |
3680 | 2200 | 1100.0 | 61.31 | 30.7 | ASCORBATE AND GLUTATHIONE: Keeping Active Oxygen Under Control. | Graham Noctor, Christine H. Foyer | Annu Rev Plant Physiol Plant Mol Biol | 1998 | 15012235 | Yes |
3681 | 6599 | 1099.8 | 169.15 | 28.2 | The capsaicin receptor: a heat-activated ion channel in the pain pathway. | M J Caterina, M A Schumacher, M Tominaga, T A Rosen, J D Levine, D Julius | Nature | 1997 | 9349813 | Yes |
3682 | 1099 | 1099.0 | 32.43 | 32.4 | Spatially heterogeneous dynamics in supercooled liquids. | M D Ediger | Annu Rev Phys Chem | 2000 | 11031277 | Yes |
3683 | 1099 | 1099.0 | 31.29 | 31.3 | Depression in the elderly. | George S Alexopoulos | Lancet | 2005 | 15936426 | No |
3684 | 2197 | 1098.5 | 75.82 | 37.9 | Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier. | Hirenkumar K Makadia, Steven J Siegel | Polymers (Basel) | 2011 | 22577513 | Yes |
3685 | 1098 | 1098.0 | 42.26 | 42.3 | The role of endothelium in the responses of vascular smooth muscle to drugs. | R F Furchgott | Annu Rev Pharmacol Toxicol | 1984 | 6203480 | No |
3686 | 2196 | 1098.0 | 48.85 | 24.4 | Cell cycle control and cancer. | L H Hartwell, M B Kastan | Science | 1994 | 7997877 | No |
3687 | 1098 | 1098.0 | 0.0 | 0.0 | Cleavage of the haem-protein link by acid methylethylketone. | F W Teale | Biochim Biophys Acta | 1959 | 13837237 | Yes |
3688 | 1098 | 1098.0 | 37.94 | 37.9 | The frailty syndrome: definition and natural history. | Qian-Li Xue | Clin Geriatr Med | 2011 | 21093718 | No |
3689 | 1097 | 1097.0 | 22.42 | 22.4 | mRNA stability in mammalian cells. | J Ross | Microbiol Rev | 1995 | 7565413 | No |
3690 | 1097 | 1097.0 | 22.79 | 22.8 | Likelihood ratio tests for detecting positive selection and application to primate lysozyme evolution. | Z Yang | Mol Biol Evol | 1998 | 9580986 | Yes |
3691 | 1097 | 1097.0 | 27.32 | 27.3 | Fibrinogen and fibrin structure and functions. | M W Mosesson | J Thromb Haemost | 2005 | 16102057 | No |
3692 | 1097 | 1097.0 | 31.92 | 31.9 | Phosphoinositides: tiny lipids with giant impact on cell regulation. | Tamas Balla | Physiol Rev | 2013 | 23899561 | No |
3693 | 2193 | 1096.5 | 0.0 | 0.0 | Micromethod for the direct determination of serum triglycerides. | E Van Handel, D B Zilversmit | J Lab Clin Med | 1957 | 13439279 | Yes |
3694 | 2192 | 1096.0 | 82.59 | 41.3 | Visual search and stimulus similarity. | J Duncan, G W Humphreys | Psychol Rev | 1989 | 2756067 | Yes |
3695 | 1096 | 1096.0 | 20.68 | 20.7 | Luciferase reporter gene vectors for analysis of promoters and enhancers. | S K Nordeen | Biotechniques | 1988 | 2908509 | Yes |
3696 | 1096 | 1096.0 | 33.95 | 34.0 | The oxidation hypothesis of atherosclerosis. | J L Witztum | Lancet | 1994 | 7916078 | No |
3697 | 2192 | 1096.0 | 45.45 | 22.7 | p53: puzzle and paradigm. | L J Ko, C Prives | Genes Dev | 1996 | 8654922 | No |
3698 | 1096 | 1096.0 | 41.1 | 41.1 | Beyond curriculum reform: confronting medicine's hidden curriculum. | F W Hafferty | Acad Med | 1998 | 9580717 | Yes |
3699 | 1096 | 1096.0 | 28.53 | 28.5 | Physiology and immunology of the cholinergic antiinflammatory pathway. | Kevin J Tracey | J Clin Invest | 2007 | 17273548 | No |
3700 | 1095 | 1095.0 | 18.31 | 18.3 | Evolution and tinkering. | F Jacob | Science | 1977 | 860134 | Yes |
3701 | 1095 | 1095.0 | 26.87 | 26.9 | DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability. | J F Ward | Prog Nucleic Acid Res Mol Biol | 1988 | 3065826 | No |
3702 | 1095 | 1095.0 | 32.54 | 32.5 | Tests for emotionality in rats and mice: a review. | J Archer | Anim Behav | 1973 | 4578750 | No |
3703 | 2190 | 1095.0 | 77.05 | 38.5 | Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry. | A I Basbaum, H L Fields | Annu Rev Neurosci | 1984 | 6143527 | No |
3704 | 2190 | 1095.0 | 98.96 | 49.5 | Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics. | J B Mulliken, J Glowacki | Plast Reconstr Surg | 1982 | 7063565 | Yes |
3705 | 1095 | 1095.0 | 21.89 | 21.9 | The sequence manipulation suite: JavaScript programs for analyzing and formatting protein and DNA sequences. | P Stothard | Biotechniques | 2000 | 10868275 | Yes |
3706 | 2190 | 1095.0 | 50.06 | 25.0 | Hepatitis C virus infection. | G M Lauer, B D Walker | N Engl J Med | 2001 | 11439948 | No |
3707 | 1095 | 1095.0 | 21.42 | 21.4 | Nonlinear structured-illumination microscopy: wide-field fluorescence imaging with theoretically unlimited resolution. | Mats G L Gustafsson | Proc Natl Acad Sci U S A | 2005 | 16141335 | Yes |
3708 | 5473 | 1094.6 | 114.71 | 22.9 | The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. | J W Harper, G R Adami, N Wei, K Keyomarsi, S J Elledge | Cell | 1993 | 8242751 | Yes |
3709 | 2189 | 1094.5 | 40.07 | 20.0 | AP-1 as a regulator of cell life and death. | Eitan Shaulian, Michael Karin | Nat Cell Biol | 2002 | 11988758 | No |
3710 | 2188 | 1094.0 | 82.49 | 41.2 | Understanding face recognition. | V Bruce, A Young | Br J Psychol | 1986 | 3756376 | Yes |
3711 | 2188 | 1094.0 | 65.58 | 32.8 | 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. | A Poland, J C Knutson | Annu Rev Pharmacol Toxicol | 1982 | 6282188 | No |
3712 | 2188 | 1094.0 | 63.35 | 31.7 | The acute phase response. | H Baumann, J Gauldie | Immunol Today | 1994 | 7512342 | No |
3713 | 1094 | 1094.0 | 25.36 | 25.4 | Selectins and their ligands: current concepts and controversies. | G S Kansas | Blood | 1996 | 8896391 | No |
3714 | 1094 | 1094.0 | 0.0 | 0.0 | Motivation reconsidered: the concept of competence. | R W White | Psychol Rev | 1959 | 13844397 | Yes |
3715 | 6564 | 1094.0 | 250.44 | 41.7 | Second-generation PLINK: rising to the challenge of larger and richer datasets. | Christopher C Chang, Carson C Chow, Laurent Cam Tellier, Shashaank Vattikuti, Shaun M Purcell, James J Lee | Gigascience | 2015 | 25722852 | Yes |
3716 | 2187 | 1093.5 | 54.92 | 27.5 | Antibacterial resistance worldwide: causes, challenges and responses. | Stuart B Levy, Bonnie Marshall | Nat Med | 2004 | 15577930 | No |
3717 | 1093 | 1093.0 | 19.67 | 19.7 | Protein denaturation. C. Theoretical models for the mechanism of denaturation. | C Tanford | Adv Protein Chem | 1970 | 4912353 | No |
3718 | 1093 | 1093.0 | 29.77 | 29.8 | Aging, energy, and oxidative stress in neurodegenerative diseases. | M F Beal | Ann Neurol | 1995 | 7668820 | No |
3719 | 1093 | 1093.0 | 0.0 | 0.0 | The purine and pyrimidine composition of deoxypentose nucleic acids. | G R Wyatt | Biochem J | 1951 | 14838906 | Yes |
3720 | 1093 | 1093.0 | 23.44 | 23.4 | Serine/threonine phosphatases: mechanism through structure. | Yigong Shi | Cell | 2009 | 19879837 | No |
3721 | 1092 | 1092.0 | 21.77 | 21.8 | Time-dependent processes in memory storage. | J L McGaugh | Science | 1966 | 5917768 | Yes |
3722 | 1092 | 1092.0 | 21.64 | 21.6 | Coiled coils: new structures and new functions. | A Lupas | Trends Biochem Sci | 1996 | 8918191 | No |
3723 | 1092 | 1092.0 | 30.66 | 30.7 | Limbic-cortical dysregulation: a proposed model of depression. | H S Mayberg | J Neuropsychiatry Clin Neurosci | 1997 | 9276848 | No |
3724 | 2184 | 1092.0 | 45.56 | 22.8 | The Hsp70 and Hsp60 chaperone machines. | B Bukau, A L Horwich | Cell | 1998 | 9476895 | No |
3725 | 1092 | 1092.0 | 23.83 | 23.8 | New ideas about atrial fibrillation 50 years on. | Stanley Nattel | Nature | 2002 | 11805846 | No |
3726 | 1092 | 1092.0 | 33.31 | 33.3 | Lanthanide luminescence for biomedical analyses and imaging. | Jean-Claude G Bünzli | Chem Rev | 2010 | 20151630 | No |
3727 | 1092 | 1092.0 | 28.66 | 28.7 | Optogenetics. | Karl Deisseroth | Nat Methods | 2011 | 21191368 | Yes |
3728 | 3274 | 1091.3 | 97.39 | 32.5 | Depression: a new animal model sensitive to antidepressant treatments. | R D Porsolt, M Le Pichon, M Jalfre | Nature | 1977 | 559941 | Yes |
3729 | 1091 | 1091.0 | 36.27 | 36.3 | Why we need observational studies to evaluate the effectiveness of health care. | N Black | BMJ | 1996 | 8634569 | Yes |
3730 | 1091 | 1091.0 | 28.02 | 28.0 | Neuropathology of Parkinson's disease. | L S Forno | J Neuropathol Exp Neurol | 1996 | 8786384 | No |
3731 | 1091 | 1091.0 | 30.38 | 30.4 | On the utility of P3 amplitude as a measure of processing capacity. | A Kok | Psychophysiology | 2001 | 11352145 | No |
3732 | 1091 | 1091.0 | 0.0 | 0.0 | The effect of emotion on cue utilization and the organization of behavior. | J A Easterbrook | Psychol Rev | 1959 | 13658305 | Yes |
3733 | 1091 | 1091.0 | 20.68 | 20.7 | mTOR and cancer: insights into a complex relationship. | David M Sabatini | Nat Rev Cancer | 2006 | 16915295 | No |
3734 | 1091 | 1091.0 | 24.21 | 24.2 | Liver regeneration. | George K Michalopoulos | J Cell Physiol | 2007 | 17559071 | No |
3735 | 5453 | 1090.6 | 164.09 | 32.8 | Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. | Salim Yusuf, Bertram Pitt, Clarence E Davis, William B Hood, Jay N Cohn | N Engl J Med | 1991 | 2057034 | Yes |
3736 | 1090 | 1090.0 | 60.9 | 60.9 | The contribution of the social environment to host resistance: the Fourth Wade Hampton Frost Lecture. | J Cassel | Am J Epidemiol | 1976 | 782233 | No |
3737 | 1090 | 1090.0 | 36.44 | 36.4 | Lipid peroxidation and antioxidants as biomarkers of tissue damage. | J M Gutteridge | Clin Chem | 1995 | 7497639 | No |
3738 | 1090 | 1090.0 | 18.43 | 18.4 | Molecular mechanisms of axon guidance. | Barry J Dickson | Science | 2002 | 12471249 | No |
3739 | 1090 | 1090.0 | 28.76 | 28.8 | Invited review: Aging and sarcopenia. | Timothy J Doherty | J Appl Physiol (1985) | 2003 | 12970377 | No |
3740 | 1090 | 1090.0 | 25.48 | 25.5 | Nitric oxide, oxidants, and protein tyrosine nitration. | Rafael Radi | Proc Natl Acad Sci U S A | 2004 | 15020765 | Yes |
3741 | 1090 | 1090.0 | 32.87 | 32.9 | Social cognition and the brain: a meta-analysis. | Frank Van Overwalle | Hum Brain Mapp | 2009 | 18381770 | Yes |
3742 | 2180 | 1090.0 | 97.37 | 48.7 | Interpreting findings from Mendelian randomization using the MR-Egger method. | Stephen Burgess, Simon G Thompson | Eur J Epidemiol | 2017 | 28527048 | Yes |
3743 | 6539 | 1089.8 | 158.94 | 26.5 | Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. | S Yusuf, P Sleight, J Pogue, J Bosch, R Davies, G Dagenais | N Engl J Med | 2000 | 10639539 | Yes |
3744 | 2179 | 1089.5 | 72.48 | 36.2 | Photoacoustic tomography: in vivo imaging from organelles to organs. | Lihong V Wang, Song Hu | Science | 2012 | 22442475 | No |
3745 | 3268 | 1089.3 | 228.85 | 76.3 | Occurrence of the potent mutagens 2- nitrobenzanthrone and 3-nitrobenzanthrone in fine airborne particles. | Aldenor G Santos, Gisele O da Rocha, Jailson B de Andrade | Sci Rep | 2019 | 30626917 | Yes |
3746 | 1089 | 1089.0 | 18.18 | 18.2 | The moulding of senescence by natural selection. | W D Hamilton | J Theor Biol | 1966 | 6015424 | Yes |
3747 | 1089 | 1089.0 | 23.92 | 23.9 | Molecular mechanisms of myocardial remodeling. | B Swynghedauw | Physiol Rev | 1999 | 9922372 | No |
3748 | 3267 | 1089.0 | 75.33 | 25.1 | Marginal structural models and causal inference in epidemiology. | J M Robins, M A Hernán, B Brumback | Epidemiology | 2000 | 10955408 | Yes |
3749 | 2178 | 1089.0 | 55.03 | 27.5 | Anemia of chronic disease. | Guenter Weiss, Lawrence T Goodnough | N Engl J Med | 2005 | 15758012 | No |
3750 | 1089 | 1089.0 | 30.24 | 30.2 | Transcranial magnetic stimulation: a primer. | Mark Hallett | Neuron | 2007 | 17640522 | No |
3751 | 1089 | 1089.0 | 24.74 | 24.7 | Structure and signalling in the IL-17 receptor family. | Sarah L Gaffen | Nat Rev Immunol | 2009 | 19575028 | No |
3752 | 1089 | 1089.0 | 32.54 | 32.5 | Periodontitis: a polymicrobial disruption of host homeostasis. | Richard P Darveau | Nat Rev Microbiol | 2010 | 20514045 | No |
3753 | 4355 | 1088.8 | 159.07 | 39.8 | Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. | K F Schulz, I Chalmers, R J Hayes, D G Altman | JAMA | 1995 | 7823387 | Yes |
3754 | 2177 | 1088.5 | 132.38 | 66.2 | Modified reagents for determination of urea and ammonia. | A L Chaney, E P Marbach | Clin Chem | 1962 | 13878063 | Yes |
3755 | 1088 | 1088.0 | 37.47 | 37.5 | Multiple organ failure. Pathophysiology and potential future therapy. | E A Deitch | Ann Surg | 1992 | 1503516 | No |
3756 | 1088 | 1088.0 | 20.6 | 20.6 | At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells. | M Kozak | J Mol Biol | 1987 | 3681984 | Yes |
3757 | 1088 | 1088.0 | 25.11 | 25.1 | P-450 metabolites of arachidonic acid in the control of cardiovascular function. | Richard J Roman | Physiol Rev | 2002 | 11773611 | No |
3758 | 1088 | 1088.0 | 0.0 | 0.0 | Aniline hydrogen phthalate as a spraying reagent for chromatography of sugars. | S M Partridge | Nature | 1949 | 18140444 | Yes |
3759 | 1088 | 1088.0 | 31.53 | 31.5 | ERK1/2 MAP kinases: structure, function, and regulation. | Robert Roskoski | Pharmacol Res | 2012 | 22569528 | No |
3760 | 1088 | 1088.0 | 31.29 | 31.3 | Serine, glycine and one-carbon units: cancer metabolism in full circle. | Jason W Locasale | Nat Rev Cancer | 2013 | 23822983 | No |
3761 | 2175 | 1087.5 | 68.15 | 34.1 | Glutamate and the pathophysiology of hypoxic--ischemic brain damage. | S M Rothman, J W Olney | Ann Neurol | 1986 | 2421636 | No |
3762 | 2174 | 1087.0 | 57.42 | 28.7 | The evolution of cooperation. | R Axelrod, W D Hamilton | Science | 1981 | 7466396 | Yes |
3763 | 2174 | 1087.0 | 0.0 | 0.0 | A revision of the Schoenheimer-Sperry method for cholesterol determination. | W M Sperry, M Webb | J Biol Chem | 1950 | 14794694 | Yes |
3764 | 1086 | 1086.0 | 18.74 | 18.7 | Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast. | R Rothstein | Methods Enzymol | 1991 | 2005793 | Yes |
3765 | 1086 | 1086.0 | 29.0 | 29.0 | Ion suppression in mass spectrometry. | Thomas M Annesley | Clin Chem | 2003 | 12816898 | No |
3766 | 2172 | 1086.0 | 61.44 | 30.7 | Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for Gram-negative bacteria. | Ivan Sondi, Branka Salopek-Sondi | J Colloid Interface Sci | 2004 | 15158396 | Yes |
3767 | 3257 | 1085.7 | 63.1 | 21.0 | Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. | Paola Scaffidi, Tom Misteli, Marco E Bianchi | Nature | 2002 | 12110890 | Yes |
3768 | 2171 | 1085.5 | 92.62 | 46.3 | Severe psoriasis--oral therapy with a new retinoid. | T Fredriksson, U Pettersson | Dermatologica | 1978 | 357213 | Yes |
3769 | 6513 | 1085.5 | 180.34 | 30.1 | Mild cognitive impairment: clinical characterization and outcome. | R C Petersen, G E Smith, S C Waring, R J Ivnik, E G Tangalos, E Kokmen | Arch Neurol | 1999 | 10190820 | Yes |
3770 | 1085 | 1085.0 | 22.53 | 22.5 | T-lymphocyte recognition of antigen in association with gene products of the major histocompatibility complex. | R H Schwartz | Annu Rev Immunol | 1985 | 2415139 | No |
3771 | 1085 | 1085.0 | 23.54 | 23.5 | The synthesis of complex carbohydrates by multiglycosyltransferase systems and their potential function in intercellular adhesion. | S Roseman | Chem Phys Lipids | 1970 | 5476326 | Yes |
3772 | 1085 | 1085.0 | 20.29 | 20.3 | Progress in human tumour immunology and immunotherapy. | S A Rosenberg | Nature | 2001 | 11357146 | No |
3773 | 1085 | 1085.0 | 33.02 | 33.0 | On the mechanisms of biocompatibility. | David F Williams | Biomaterials | 2008 | 18440630 | No |
3774 | 2169 | 1084.5 | 153.5 | 76.8 | Osteoarthritis. | David J Hunter, Sita Bierma-Zeinstra | Lancet | 2019 | 31034380 | No |
3775 | 1084 | 1084.0 | 26.69 | 26.7 | Anti-inflammatory actions of glucocorticoids: molecular mechanisms. | P J Barnes | Clin Sci (Lond) | 1998 | 9854452 | No |
3776 | 1084 | 1084.0 | 11.55 | 11.6 | The Permeability Of Capillaries In Various Organs As Determined By Use Of The 'Indicator Diffusion' Method. | C Crone | Acta Physiol Scand | 1963 | 14078649 | Yes |
3777 | 1084 | 1084.0 | 25.19 | 25.2 | Perylene bisimide dyes as versatile building blocks for functional supramolecular architectures. | Frank Würthner | Chem Commun (Camb) | 2004 | 15263926 | Yes |
3778 | 6504 | 1084.0 | 150.46 | 25.1 | Enzymatic assembly of DNA molecules up to several hundred kilobases. | Daniel G Gibson, Lei Young, Ray-Yuan Chuang, J Craig Venter, Clyde A Hutchison, Hamilton O Smith | Nat Methods | 2009 | 19363495 | Yes |
3779 | 1084 | 1084.0 | 43.25 | 43.2 | Epidemiology and risk factors for IBD. | Ashwin N Ananthakrishnan | Nat Rev Gastroenterol Hepatol | 2015 | 25732745 | No |
3780 | 1084 | 1084.0 | 65.84 | 65.8 | Stop Explaining Black Box Machine Learning Models for High Stakes Decisions and Use Interpretable Models Instead. | Cynthia Rudin | Nat Mach Intell | 2019 | 35603010 | Yes |
3781 | 2167 | 1083.5 | 64.79 | 32.4 | A rapid, sensitive, and versatile assay for protein using Coomassie brilliant blue G250. | J J Sedmak, S E Grossberg | Anal Biochem | 1977 | 68686 | Yes |
3782 | 2167 | 1083.5 | 50.88 | 25.4 | Peroxidase-labeled antibody. A new method of conjugation. | P K Nakane, A Kawaoi | J Histochem Cytochem | 1974 | 4443551 | Yes |
3783 | 1083 | 1083.0 | 45.29 | 45.3 | Corticosteroids and lymphoid cells. | H N Claman | N Engl J Med | 1972 | 5043524 | Yes |
3784 | 1083 | 1083.0 | 26.19 | 26.2 | Looking into the functional architecture of the brain with diffusion MRI. | Denis Le Bihan | Nat Rev Neurosci | 2003 | 12778119 | No |
3785 | 1083 | 1083.0 | 53.37 | 53.4 | Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress. | Helmut Sies | Redox Biol | 2017 | 28110218 | No |
3786 | 1083 | 1083.0 | 43.15 | 43.1 | The non-canonical NF-κB pathway in immunity and inflammation. | Shao-Cong Sun | Nat Rev Immunol | 2017 | 28580957 | No |
3787 | 2165 | 1082.5 | 48.31 | 24.2 | Effect of pegylation on pharmaceuticals. | J Milton Harris, Robert B Chess | Nat Rev Drug Discov | 2003 | 12612647 | No |
3788 | 2164 | 1082.0 | 70.23 | 35.1 | Population growth makes waves in the distribution of pairwise genetic differences. | A R Rogers, H Harpending | Mol Biol Evol | 1992 | 1316531 | Yes |
3789 | 2164 | 1082.0 | 43.47 | 21.7 | In search of the 'missing self': MHC molecules and NK cell recognition. | H G Ljunggren, K Kärre | Immunol Today | 1990 | 2201309 | No |
3790 | 1082 | 1082.0 | 44.6 | 44.6 | Clinical experience with impedance audiometry. | J Jerger | Arch Otolaryngol | 1970 | 5455571 | Yes |
3791 | 5410 | 1082.0 | 195.69 | 39.1 | A new clinical scale for the staging of dementia. | C P Hughes, L Berg, W L Danziger, L A Coben, R L Martin | Br J Psychiatry | 1982 | 7104545 | Yes |
3792 | 1082 | 1082.0 | 35.55 | 35.5 | Perceptual load as a necessary condition for selective attention. | N Lavie | J Exp Psychol Hum Percept Perform | 1995 | 7790827 | Yes |
3793 | 1082 | 1082.0 | 10.87 | 10.9 | Cardiac nucleotides in hypoxia: possible role in regulation of coronary blood flow. | R M Berne | Am J Physiol | 1963 | 13971060 | Yes |
3794 | 1082 | 1082.0 | 40.61 | 40.6 | Electrolytes and interphases in Li-ion batteries and beyond. | Kang Xu | Chem Rev | 2014 | 25351820 | Yes |
3795 | 2162 | 1081.0 | 53.81 | 26.9 | The regulation and function of c-fos and other immediate early genes in the nervous system. | M Sheng, M E Greenberg | Neuron | 1990 | 1969743 | No |
3796 | 1081 | 1081.0 | 26.55 | 26.6 | The glycemic index: physiological mechanisms relating to obesity, diabetes, and cardiovascular disease. | David S Ludwig | JAMA | 2002 | 11988062 | No |
3797 | 1081 | 1081.0 | 35.01 | 35.0 | Dual-processing accounts of reasoning, judgment, and social cognition. | Jonathan St B T Evans | Annu Rev Psychol | 2008 | 18154502 | No |
3798 | 2161 | 1080.5 | 47.0 | 23.5 | Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age. | T Hunter, J Pines | Cell | 1994 | 7954824 | No |
3799 | 1080 | 1080.0 | 54.3 | 54.3 | The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): a clinical investigation of 225 patients using ambulatory 24-hour pH monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury. | J A Koufman | Laryngoscope | 1991 | 1895864 | No |
3800 | 1080 | 1080.0 | 40.96 | 41.0 | A new international staging system for lung cancer. | C F Mountain | Chest | 1986 | 3514171 | No |
3801 | 1080 | 1080.0 | 19.15 | 19.1 | Radiochemical micro assays for the determination of choline acetyltransferase and acetylcholinesterase activities. | F Fonnum | Biochem J | 1969 | 4982085 | Yes |
3802 | 4320 | 1080.0 | 101.99 | 25.5 | The epidemiology of sepsis in the United States from 1979 through 2000. | Greg S Martin, David M Mannino, Stephanie Eaton, Marc Moss | N Engl J Med | 2003 | 12700374 | Yes |
3803 | 1080 | 1080.0 | 29.08 | 29.1 | A perspective on judgment and choice: mapping bounded rationality. | Daniel Kahneman | Am Psychol | 2003 | 14584987 | No |
3804 | 1080 | 1080.0 | 45.19 | 45.2 | Bisphenol A and human health: a review of the literature. | Johanna R Rochester | Reprod Toxicol | 2013 | 23994667 | No |
3805 | 2159 | 1079.5 | 83.46 | 41.7 | Hearing lips and seeing voices. | H McGurk, J MacDonald | Nature | 1976 | 1012311 | Yes |
3806 | 2159 | 1079.5 | 39.63 | 19.8 | Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method. | R Daniel Gietz, Robin A Woods | Methods Enzymol | 2002 | 12073338 | Yes |
3807 | 2159 | 1079.5 | 64.34 | 32.2 | The memory function of sleep. | Susanne Diekelmann, Jan Born | Nat Rev Neurosci | 2010 | 20046194 | No |
3808 | 1079 | 1079.0 | 26.66 | 26.7 | Avidin. | N M Green | Adv Protein Chem | 1975 | 237414 | Yes |
3809 | 1079 | 1079.0 | 27.24 | 27.2 | Selectins: interpreters of cell-specific carbohydrate information during inflammation. | L A Lasky | Science | 1992 | 1439808 | No |
3810 | 1079 | 1079.0 | 42.36 | 42.4 | Gait changes in older adults: predictors of falls or indicators of fear. | B E Maki | J Am Geriatr Soc | 1997 | 9063277 | Yes |
3811 | 1079 | 1079.0 | 26.51 | 26.5 | Biological effects of resveratrol. | L Frémont | Life Sci | 2000 | 10680575 | No |
3812 | 3237 | 1079.0 | 70.11 | 23.4 | Population structure and eigenanalysis. | Nick Patterson, Alkes L Price, David Reich | PLoS Genet | 2006 | 17194218 | Yes |
3813 | 1079 | 1079.0 | 30.25 | 30.2 | The mechanisms of alloxan- and streptozotocin-induced diabetes. | S Lenzen | Diabetologia | 2008 | 18087688 | No |
3814 | 2158 | 1079.0 | 53.88 | 26.9 | An improved general amino acid replacement matrix. | Si Quang Le, Olivier Gascuel | Mol Biol Evol | 2008 | 18367465 | Yes |
3815 | 3236 | 1078.7 | 168.11 | 56.0 | Relatives of the impaired elderly: correlates of feelings of burden. | S H Zarit, K E Reever, J Bach-Peterson | Gerontologist | 1980 | 7203086 | Yes |
3816 | 2157 | 1078.5 | 43.26 | 21.6 | A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli. | C S Hoffman, F Winston | Gene | 1987 | 3319781 | Yes |
3817 | 6471 | 1078.5 | 138.52 | 23.1 | Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. | D A Melton, P A Krieg, M R Rebagliati, T Maniatis, K Zinn, M R Green | Nucleic Acids Res | 1984 | 6091052 | Yes |
3818 | 5391 | 1078.2 | 200.99 | 40.2 | Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. | Jonathan D Power, Kelly A Barnes, Abraham Z Snyder, Bradley L Schlaggar, Steven E Petersen | Neuroimage | 2012 | 22019881 | Yes |
3819 | 1078 | 1078.0 | 32.98 | 33.0 | Association of the B-cell alloantigen DRw4 with rheumatoid arthritis. | P Stastny | N Engl J Med | 1978 | 147420 | Yes |
3820 | 1078 | 1078.0 | 30.62 | 30.6 | Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are onco-developmental antigens. | T Feizi | Nature | 1985 | 2579340 | Yes |
3821 | 1078 | 1078.0 | 29.95 | 29.9 | A teacher rating scale for use in drug studies with children. | C K Conners | Am J Psychiatry | 1969 | 4900822 | Yes |
3822 | 1078 | 1078.0 | 34.9 | 34.9 | Why people use health services. | I M Rosenstock | Milbank Mem Fund Q | 1966 | 5967464 | Yes |
3823 | 1078 | 1078.0 | 23.11 | 23.1 | PHD: predicting one-dimensional protein structure by profile-based neural networks. | B Rost | Methods Enzymol | 1996 | 8743704 | Yes |
3824 | 1078 | 1078.0 | 26.95 | 26.9 | Targeting cancer metabolism: a therapeutic window opens. | Matthew G Vander Heiden | Nat Rev Drug Discov | 2011 | 21878982 | No |
3825 | 6464 | 1077.3 | 173.15 | 28.9 | Cancer statistics, 2007. | Ahmedin Jemal, Rebecca Siegel, Elizabeth Ward, Taylor Murray, Jiaquan Xu, Michael J Thun | CA Cancer J Clin | 2007 | 17237035 | Yes |
3826 | 2154 | 1077.0 | 63.49 | 31.7 | Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation. | J M Reul, E R de Kloet | Endocrinology | 1985 | 2998738 | Yes |
3827 | 1077 | 1077.0 | 27.44 | 27.4 | Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system. | J P Tam | Proc Natl Acad Sci U S A | 1988 | 3399498 | Yes |
3828 | 1077 | 1077.0 | 27.05 | 27.1 | Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol. | M J Berridge | Biochem J | 1983 | 6309155 | Yes |
3829 | 4308 | 1077.0 | 111.07 | 27.8 | A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. | I Vermes, C Haanen, H Steffens-Nakken, C Reutelingsperger | J Immunol Methods | 1995 | 7622868 | Yes |
3830 | 2154 | 1077.0 | 44.73 | 22.4 | Mitogen-activated protein kinase pathways. | M J Robinson, M H Cobb | Curr Opin Cell Biol | 1997 | 9069255 | No |
3831 | 2154 | 1077.0 | 37.81 | 18.9 | Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. | W Gu, R G Roeder | Cell | 1997 | 9288740 | Yes |
3832 | 1077 | 1077.0 | 18.72 | 18.7 | Regulatory T cells in autoimmmunity*. | E M Shevach | Annu Rev Immunol | 2000 | 10837065 | No |
3833 | 2154 | 1077.0 | 83.73 | 41.9 | Chronic catheterization of the spinal subarachnoid space. | T L Yaksh, T A Rudy | Physiol Behav | 1976 | 14677603 | Yes |
3834 | 1077 | 1077.0 | 29.56 | 29.6 | Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review. | John W Newcomer | CNS Drugs | 2005 | 15998156 | No |
3835 | 1077 | 1077.0 | 24.93 | 24.9 | Sjögren's syndrome. | Robert I Fox | Lancet | 2005 | 16039337 | No |
3836 | 1077 | 1077.0 | 36.3 | 36.3 | Drug transport across the blood-brain barrier. | William M Pardridge | J Cereb Blood Flow Metab | 2012 | 22929442 | No |
3837 | 1076 | 1076.0 | 28.88 | 28.9 | Statistical quality control and routine data processing for radioimmunoassays and immunoradiometric assays. | D Rodbard | Clin Chem | 1974 | 4370388 | No |
3838 | 1076 | 1076.0 | 37.51 | 37.5 | Coronary physiology. | E O Feigl | Physiol Rev | 1983 | 6296890 | No |
3839 | 1076 | 1076.0 | 38.9 | 38.9 | Relativistic electronic-structure calculations employing a two-component no-pair formalism with external-field projection operators. | B A Hess | Phys Rev A Gen Phys | 1986 | 9897114 | Yes |
3840 | 1076 | 1076.0 | 32.51 | 32.5 | Pectin structure and biosynthesis. | Debra Mohnen | Curr Opin Plant Biol | 2008 | 18486536 | No |
3841 | 2152 | 1076.0 | 88.13 | 44.1 | Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression. | Christoph Hafemeister, Rahul Satija | Genome Biol | 2019 | 31870423 | Yes |
3842 | 7531 | 1075.9 | 130.97 | 18.7 | The human genome browser at UCSC. | W James Kent, Charles W Sugnet, Terrence S Furey, Krishna M Roskin, Tom H Pringle, Alan M Zahler, David Haussler | Genome Res | 2002 | 12045153 | Yes |
3843 | 2151 | 1075.5 | 67.02 | 33.5 | Polymyositis and dermatomyositis (second of two parts). | A Bohan, J B Peter | N Engl J Med | 1975 | 1089199 | No |
3844 | 2151 | 1075.5 | 62.24 | 31.1 | Accurate molecular van der Waals interactions from ground-state electron density and free-atom reference data. | Alexandre Tkatchenko, Matthias Scheffler | Phys Rev Lett | 2009 | 19257665 | Yes |
3845 | 1075 | 1075.0 | 29.28 | 29.3 | Synchronization of cortical activity and its putative role in information processing and learning. | W Singer | Annu Rev Physiol | 1993 | 8466179 | No |
3846 | 1075 | 1075.0 | 51.24 | 51.2 | Using Bayes to get the most out of non-significant results. | Zoltan Dienes | Front Psychol | 2014 | 25120503 | Yes |
3847 | 1075 | 1075.0 | 34.04 | 34.0 | Isolation By Distance In Equilibrium And Non-Equilibrium Populations. | Montgomery Slatkin | Evolution | 1993 | 28568097 | Yes |
3848 | 1074 | 1074.0 | 42.09 | 42.1 | Functional connections between cells as revealed by dye-coupling with a highly fluorescent naphthalimide tracer. | W W Stewart | Cell | 1978 | 688392 | Yes |
3849 | 1074 | 1074.0 | 33.37 | 33.4 | Food reward: brain substrates of wanting and liking. | K C Berridge | Neurosci Biobehav Rev | 1996 | 8622814 | No |
3850 | 1074 | 1074.0 | 21.28 | 21.3 | Automated NMR structure calculation with CYANA. | Peter Güntert | Methods Mol Biol | 2004 | 15318003 | Yes |
3851 | 1074 | 1074.0 | 35.81 | 35.8 | What Good Are Positive Emotions? | Barbara L Fredrickson | Rev Gen Psychol | 1998 | 21850154 | Yes |
3852 | 2147 | 1073.5 | 83.79 | 41.9 | Glutathione reductase. | I Carlberg, B Mannervik | Methods Enzymol | 1985 | 3003504 | Yes |
3853 | 1073 | 1073.0 | 30.98 | 31.0 | Microbial heavy-metal resistance. | D H Nies | Appl Microbiol Biotechnol | 1999 | 10422221 | No |
3854 | 1073 | 1073.0 | 28.63 | 28.6 | Inhibition of return. | R M Klein | Trends Cogn Sci | 2000 | 10740278 | Yes |
3855 | 1073 | 1073.0 | 25.63 | 25.6 | Context, ambiguity, and unlearning: sources of relapse after behavioral extinction. | Mark E Bouton | Biol Psychiatry | 2002 | 12437938 | No |
3856 | 1073 | 1073.0 | 0.0 | 0.0 | The concentration of sympathin in different parts of the central nervous system under normal conditions and after the administration of drugs. | M Vogt | J Physiol | 1954 | 13152692 | Yes |
3857 | 2146 | 1073.0 | 48.15 | 24.1 | Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering. | Sharon R Browning, Brian L Browning | Am J Hum Genet | 2007 | 17924348 | Yes |
3858 | 2145 | 1072.5 | 105.94 | 53.0 | Optimism, coping, and health: assessment and implications of generalized outcome expectancies. | M F Scheier, C S Carver | Health Psychol | 1985 | 4029106 | Yes |
3859 | 1072 | 1072.0 | 77.89 | 77.9 | Fibula free flap: a new method of mandible reconstruction. | D A Hidalgo | Plast Reconstr Surg | 1989 | 2734406 | Yes |
3860 | 1072 | 1072.0 | 30.48 | 30.5 | Muscarinic receptors--characterization, coupling and function. | M P Caulfield | Pharmacol Ther | 1993 | 7504306 | No |
3861 | 1072 | 1072.0 | 18.88 | 18.9 | Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. | W Kolch | Biochem J | 2000 | 11023813 | No |
3862 | 1072 | 1072.0 | 33.99 | 34.0 | Determining association constants from titration experiments in supramolecular chemistry. | Pall Thordarson | Chem Soc Rev | 2011 | 21125111 | Yes |
3863 | 2144 | 1072.0 | 57.61 | 28.8 | Targeting hypoxia in cancer therapy. | William R Wilson, Michael P Hay | Nat Rev Cancer | 2011 | 21606941 | No |
3864 | 2144 | 1072.0 | 91.01 | 45.5 | Extended international (IOTF) body mass index cut-offs for thinness, overweight and obesity. | T J Cole, T Lobstein | Pediatr Obes | 2012 | 22715120 | Yes |
3865 | 6430 | 1071.7 | 163.17 | 27.2 | Ghrelin is a growth-hormone-releasing acylated peptide from stomach. | M Kojima, H Hosoda, Y Date, M Nakazato, H Matsuo, K Kangawa | Nature | 1999 | 10604470 | Yes |
3866 | 4285 | 1071.2 | 106.72 | 26.7 | An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. | Joseph A Maldjian, Paul J Laurienti, Robert A Kraft, Jonathan H Burdette | Neuroimage | 2003 | 12880848 | Yes |
3867 | 4284 | 1071.0 | 110.12 | 27.5 | Real time quantitative PCR. | C A Heid, J Stevens, K J Livak, P M Williams | Genome Res | 1996 | 8908518 | Yes |
3868 | 1071 | 1071.0 | 32.17 | 32.2 | Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators. | Bruce S McEwen | Eur J Pharmacol | 2008 | 18282566 | No |
3869 | 5355 | 1071.0 | 175.56 | 35.1 | CD-HIT: accelerated for clustering the next-generation sequencing data. | Limin Fu, Beifang Niu, Zhengwei Zhu, Sitao Wu, Weizhong Li | Bioinformatics | 2012 | 23060610 | Yes |
3870 | 2141 | 1070.5 | 63.33 | 31.7 | Extended-spectrum beta-lactamases: a clinical update. | David L Paterson, Robert A Bonomo | Clin Microbiol Rev | 2005 | 16223952 | No |
3871 | 2141 | 1070.5 | 53.21 | 26.6 | The regulation of IL-10 production by immune cells. | Margarida Saraiva, Anne O'Garra | Nat Rev Immunol | 2010 | 20154735 | No |
3872 | 1070 | 1070.0 | 0.0 | 0.0 | Neural basis of the spontaneous optokinetic response produced by visual inversion. | R W Sperry | J Comp Physiol Psychol | 1950 | 14794830 | Yes |
3873 | 1070 | 1070.0 | 25.72 | 25.7 | Metagenomics: application of genomics to uncultured microorganisms. | Jo Handelsman | Microbiol Mol Biol Rev | 2004 | 15590779 | No |
3874 | 4279 | 1069.8 | 115.33 | 28.8 | Gene ontology analysis for RNA-seq: accounting for selection bias. | Matthew D Young, Matthew J Wakefield, Gordon K Smyth, Alicia Oshlack | Genome Biol | 2010 | 20132535 | Yes |
3875 | 6419 | 1069.8 | 271.3 | 45.2 | GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses. | Zefang Tang, Chenwei Li, Boxi Kang, Ge Gao, Cheng Li, Zemin Zhang | Nucleic Acids Res | 2017 | 28407145 | Yes |
3876 | 2139 | 1069.5 | 45.51 | 22.8 | InterProScan--an integration platform for the signature-recognition methods in InterPro. | E M Zdobnov, R Apweiler | Bioinformatics | 2001 | 11590104 | Yes |
3877 | 1069 | 1069.0 | 29.5 | 29.5 | Mitochondrial genetics: a paradigm for aging and degenerative diseases? | D C Wallace | Science | 1992 | 1533953 | Yes |
3878 | 1069 | 1069.0 | 23.37 | 23.4 | ECM and cell surface proteolysis: regulating cellular ecology. | Z Werb | Cell | 1997 | 9390552 | No |
3879 | 2138 | 1069.0 | 44.15 | 22.1 | TM-align: a protein structure alignment algorithm based on the TM-score. | Yang Zhang, Jeffrey Skolnick | Nucleic Acids Res | 2005 | 15849316 | Yes |
3880 | 1069 | 1069.0 | 36.68 | 36.7 | Stochastic thermodynamics, fluctuation theorems and molecular machines. | Udo Seifert | Rep Prog Phys | 2012 | 23168354 | No |
3881 | 2138 | 1069.0 | 80.1 | 40.0 | Inflammasomes: mechanism of assembly, regulation and signalling. | Petr Broz, Vishva M Dixit | Nat Rev Immunol | 2016 | 27291964 | No |
3882 | 2137 | 1068.5 | 63.08 | 31.5 | Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. | C N Hales, D J Barker | Diabetologia | 1992 | 1644236 | No |
3883 | 1068 | 1068.0 | 44.01 | 44.0 | Movement, posture and equilibrium: interaction and coordination. | J Massion | Prog Neurobiol | 1992 | 1736324 | No |
3884 | 2136 | 1068.0 | 79.83 | 39.9 | A psychomotor stimulant theory of addiction. | R A Wise, M A Bozarth | Psychol Rev | 1987 | 3317472 | No |
3885 | 1068 | 1068.0 | 26.02 | 26.0 | Ratio of neutrophil to lymphocyte counts--rapid and simple parameter of systemic inflammation and stress in critically ill. | R Zahorec | Bratisl Lek Listy | 2001 | 11723675 | Yes |
3886 | 1068 | 1068.0 | 24.0 | 24.0 | The neurobiology of consolidations, or, how stable is the engram? | Yadin Dudai | Annu Rev Psychol | 2004 | 14744210 | No |
3887 | 1068 | 1068.0 | 30.65 | 30.6 | Distracted and confused?: selective attention under load. | Nilli Lavie | Trends Cogn Sci | 2005 | 15668100 | No |
3888 | 2136 | 1068.0 | 64.15 | 32.1 | Regulation of type I interferon responses. | Lionel B Ivashkiv, Laura T Donlin | Nat Rev Immunol | 2014 | 24362405 | No |
3889 | 4270 | 1067.5 | 81.87 | 20.5 | DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. | M Okano, D W Bell, D A Haber, E Li | Cell | 1999 | 10555141 | Yes |
3890 | 1067 | 1067.0 | 39.64 | 39.6 | Infection by verocytotoxin-producing Escherichia coli. | M A Karmali | Clin Microbiol Rev | 1989 | 2644022 | No |
3891 | 1067 | 1067.0 | 27.01 | 27.0 | Axonal growth-associated proteins. | J H Skene | Annu Rev Neurosci | 1989 | 2648946 | No |
3892 | 1067 | 1067.0 | 23.19 | 23.2 | The tragedy of the commons. The population problem has no technical solution; it requires a fundamental extension in morality. | G Hardin | Science | 1968 | 5699198 | Yes |
3893 | 1067 | 1067.0 | 32.9 | 32.9 | Chronic stress, drug use, and vulnerability to addiction. | Rajita Sinha | Ann N Y Acad Sci | 2008 | 18991954 | No |
3894 | 1067 | 1067.0 | 33.94 | 33.9 | Staphylococcus epidermidis--the 'accidental' pathogen. | Michael Otto | Nat Rev Microbiol | 2009 | 19609257 | No |
3895 | 1067 | 1067.0 | 32.01 | 32.0 | The multiple-demand (MD) system of the primate brain: mental programs for intelligent behaviour. | John Duncan | Trends Cogn Sci | 2010 | 20171926 | No |
3896 | 2133 | 1066.5 | 37.34 | 18.7 | Calcium-dependent bacteriophage DNA infection. | M Mandel, A Higa | J Mol Biol | 1970 | 4922220 | Yes |
3897 | 4265 | 1066.2 | 217.82 | 54.5 | National Institute of Mental Health Diagnostic Interview Schedule. Its history, characteristics, and validity. | L N Robins, J E Helzer, J Croughan, K S Ratcliff | Arch Gen Psychiatry | 1981 | 6260053 | Yes |
3898 | 1066 | 1066.0 | 29.14 | 29.1 | Reactive species and antioxidants. Redox biology is a fundamental theme of aerobic life. | Barry Halliwell | Plant Physiol | 2006 | 16760481 | Yes |
3899 | 2132 | 1066.0 | 44.24 | 22.1 | Fcgamma receptors as regulators of immune responses. | Falk Nimmerjahn, Jeffrey V Ravetch | Nat Rev Immunol | 2008 | 18064051 | No |
3900 | 3196 | 1065.3 | 81.05 | 27.0 | Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions. | M Piotto, V Saudek, V Sklenár | J Biomol NMR | 1992 | 1490109 | Yes |
3901 | 3196 | 1065.3 | 107.2 | 35.7 | A new rating scale for Alzheimer's disease. | W G Rosen, R C Mohs, K L Davis | Am J Psychiatry | 1984 | 6496779 | Yes |
3902 | 1065 | 1065.0 | 30.08 | 30.1 | Epidemiology of cancer of the colon and rectum. | D P Burkitt | Cancer | 1971 | 5165022 | Yes |
3903 | 1065 | 1065.0 | 23.12 | 23.1 | Human papillomavirus and cervical cancer. | Eileen M Burd | Clin Microbiol Rev | 2003 | 12525422 | No |
3904 | 1065 | 1065.0 | 0.0 | 0.0 | On the prediction of occurrence of particular verbal intrusions in immediate recall. | J Deese | J Exp Psychol | 1959 | 13664879 | Yes |
3905 | 1065 | 1065.0 | 67.25 | 67.2 | Critical Analysis of Strategies for Determining Rigor in Qualitative Inquiry. | Janice M Morse | Qual Health Res | 2015 | 26184336 | Yes |
3906 | 2129 | 1064.5 | 59.43 | 29.7 | Binding of soluble form of fibroblast surface protein, fibronectin, to collagen. | E Engvall, E Ruoslahti | Int J Cancer | 1977 | 903179 | Yes |
3907 | 2129 | 1064.5 | 72.92 | 36.5 | Liquid phase condensation in cell physiology and disease. | Yongdae Shin, Clifford P Brangwynne | Science | 2017 | 28935776 | No |
3908 | 2128 | 1064.0 | 71.19 | 35.6 | The pathogenesis of atherosclerosis (first of two parts). | R Ross, J A Glomset | N Engl J Med | 1976 | 819830 | No |
3909 | 1064 | 1064.0 | 26.34 | 26.3 | Skeletal complications of malignancy. | R E Coleman | Cancer | 1997 | 9362426 | No |
3910 | 1064 | 1064.0 | 23.28 | 23.3 | Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. | J Denis McGarry | Diabetes | 2002 | 11756317 | No |
3911 | 1064 | 1064.0 | 22.67 | 22.7 | Ligand-targeted therapeutics in anticancer therapy. | Theresa M Allen | Nat Rev Cancer | 2002 | 12360278 | No |
3912 | 1064 | 1064.0 | 21.94 | 21.9 | Oxidant signals and oxidative stress. | Toren Finkel | Curr Opin Cell Biol | 2003 | 12648682 | No |
3913 | 1064 | 1064.0 | 0.0 | 0.0 | A Serological Differentiation Of Human And Other Groups Of Hemolytic Streptococci. | R C Lancefield | J Exp Med | 1933 | 19870148 | Yes |
3914 | 2128 | 1064.0 | 62.34 | 31.2 | Mitochondria: in sickness and in health. | Jodi Nunnari, Anu Suomalainen | Cell | 2012 | 22424226 | No |
3915 | 2127 | 1063.5 | 87.73 | 43.9 | A real-time QRS detection algorithm. | J Pan, W J Tompkins | IEEE Trans Biomed Eng | 1985 | 3997178 | Yes |
3916 | 2127 | 1063.5 | 55.15 | 27.6 | Sterile inflammation: sensing and reacting to damage. | Grace Y Chen, Gabriel Nuñez | Nat Rev Immunol | 2010 | 21088683 | No |
3917 | 1063 | 1063.0 | 24.76 | 24.8 | Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note. | S H Kaufmann | Cancer Res | 1989 | 2790800 | Yes |
3918 | 2126 | 1063.0 | 0.0 | 0.0 | A microcolorimetric method for the determination of inorganic phosphorus. | H H Taussky, E Shorr | J Biol Chem | 1953 | 13061491 | Yes |
3919 | 1063 | 1063.0 | 32.23 | 32.2 | Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxia. | Rakesh K Jain | Cancer Cell | 2014 | 25517747 | No |
3920 | 3187 | 1062.3 | 149.02 | 49.7 | Surface markers on human T and B lymphocytes. I. A large population of lymphocytes forming nonimmune rosettes with sheep red blood cells. | M Jondal, G Holm, H Wigzell | J Exp Med | 1972 | 4114496 | Yes |
3921 | 1062 | 1062.0 | 36.36 | 36.4 | A theory of visual attention. | C Bundesen | Psychol Rev | 1990 | 2247540 | Yes |
3922 | 1062 | 1062.0 | 28.89 | 28.9 | Microtubule formation in vitro in solutions containing low calcium concentrations. | R C Weisenberg | Science | 1972 | 4626639 | Yes |
3923 | 1062 | 1062.0 | 32.79 | 32.8 | Prevention of drug access to bacterial targets: permeability barriers and active efflux. | H Nikaido | Science | 1994 | 8153625 | No |
3924 | 2124 | 1062.0 | 48.12 | 24.1 | The significance of digital gene expression profiles. | S Audic, J M Claverie | Genome Res | 1997 | 9331369 | Yes |
3925 | 1062 | 1062.0 | 13.9 | 13.9 | Relative and absolute strength of response as a function of frequency of reinforcement. | R J Herrnstein | J Exp Anal Behav | 1961 | 13713775 | Yes |
3926 | 1062 | 1062.0 | 31.85 | 31.9 | G(ST) and its relatives do not measure differentiation. | Lou Jost | Mol Ecol | 2008 | 19238703 | Yes |
3927 | 2124 | 1062.0 | 56.63 | 28.3 | Cancer epigenetics: from mechanism to therapy. | Mark A Dawson, Tony Kouzarides | Cell | 2012 | 22770212 | No |
3928 | 3186 | 1062.0 | 114.68 | 38.2 | Stimuli-responsive nanocarriers for drug delivery. | Simona Mura, Julien Nicolas, Patrick Couvreur | Nat Mater | 2013 | 24150417 | No |
3929 | 2123 | 1061.5 | 40.06 | 20.0 | Wnt signaling: a common theme in animal development. | K M Cadigan, R Nusse | Genes Dev | 1997 | 9407023 | No |
3930 | 1061 | 1061.0 | 29.23 | 29.2 | Junctional intercellular communication: the cell-to-cell membrane channel. | W R Loewenstein | Physiol Rev | 1981 | 6270711 | No |
3931 | 1061 | 1061.0 | 30.32 | 30.3 | Pathogenetic mechanisms of septic shock. | J E Parrillo | N Engl J Med | 1993 | 8479467 | No |
3932 | 3183 | 1061.0 | 76.08 | 25.4 | Nitric oxide and macrophage function. | J MacMicking, Q W Xie, C Nathan | Annu Rev Immunol | 1997 | 9143691 | No |
3933 | 1061 | 1061.0 | 29.66 | 29.7 | Micellar nanocarriers: pharmaceutical perspectives. | V P Torchilin | Pharm Res | 2007 | 17109211 | No |
3934 | 1061 | 1061.0 | 31.4 | 31.4 | pegas: an R package for population genetics with an integrated-modular approach. | Emmanuel Paradis | Bioinformatics | 2010 | 20080509 | Yes |
3935 | 1061 | 1061.0 | 31.13 | 31.1 | Regulation of immune responses by prostaglandin E2. | Pawel Kalinski | J Immunol | 2012 | 22187483 | No |
3936 | 1061 | 1061.0 | 28.48 | 28.5 | The complex world of WNT receptor signalling. | Christof Niehrs | Nat Rev Mol Cell Biol | 2012 | 23151663 | No |
3937 | 2121 | 1060.5 | 51.44 | 25.7 | Determination of alkali and halide monovalent ion parameters for use in explicitly solvated biomolecular simulations. | In Suk Joung, Thomas E Cheatham | J Phys Chem B | 2008 | 18593145 | Yes |
3938 | 1060 | 1060.0 | 10.88 | 10.9 | Kinetic proofreading: a new mechanism for reducing errors in biosynthetic processes requiring high specificity. | J J Hopfield | Proc Natl Acad Sci U S A | 1974 | 4530290 | Yes |
3939 | 1060 | 1060.0 | 30.05 | 30.1 | Autoantibodies to nuclear antigens (ANA): their immunobiology and medicine. | E M Tan | Adv Immunol | 1982 | 6182766 | No |
3940 | 2118 | 1059.0 | 81.7 | 40.9 | Analysis of probability as an aid in the clinical diagnosis of coronary-artery disease. | G A Diamond, J S Forrester | N Engl J Med | 1979 | 440357 | Yes |
3941 | 1059 | 1059.0 | 36.77 | 36.8 | A colorimetric method for estimating serum triglycerides. | M J Fletcher | Clin Chim Acta | 1968 | 5696963 | Yes |
3942 | 1059 | 1059.0 | 26.05 | 26.1 | Omega-3 fatty acids in inflammation and autoimmune diseases. | Artemis P Simopoulos | J Am Coll Nutr | 2002 | 12480795 | No |
3943 | 1059 | 1059.0 | 23.04 | 23.0 | Antimicrobial reactive oxygen and nitrogen species: concepts and controversies. | Ferric C Fang | Nat Rev Microbiol | 2004 | 15378046 | No |
3944 | 2118 | 1059.0 | 45.83 | 22.9 | Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. | P J Roberts, C J Der | Oncogene | 2007 | 17496923 | No |
3945 | 4235 | 1058.8 | 144.81 | 36.2 | Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. | S Pellow, P Chopin, S E File, M Briley | J Neurosci Methods | 1985 | 2864480 | Yes |
3946 | 3176 | 1058.7 | 131.16 | 43.7 | A new method for detecting anaerobic threshold by gas exchange. | W L Beaver, K Wasserman, B J Whipp | J Appl Physiol (1985) | 1986 | 3087938 | Yes |
3947 | 2117 | 1058.5 | 54.11 | 27.1 | Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles. | Donald E Owens, Nicholas A Peppas | Int J Pharm | 2006 | 16303268 | No |
3948 | 2117 | 1058.5 | 57.72 | 28.9 | The AMPK signalling pathway coordinates cell growth, autophagy and metabolism. | Maria M Mihaylova, Reuben J Shaw | Nat Cell Biol | 2011 | 21892142 | No |
3949 | 2117 | 1058.5 | 161.54 | 80.8 | Reactive oxygen species (ROS) as pleiotropic physiological signalling agents. | Helmut Sies, Dean P Jones | Nat Rev Mol Cell Biol | 2020 | 32231263 | No |
3950 | 1058 | 1058.0 | 40.07 | 40.1 | The ovariectomized rat model of postmenopausal bone loss. | D N Kalu | Bone Miner | 1991 | 1773131 | No |
3951 | 1058 | 1058.0 | 24.55 | 24.6 | Biochemistry and genetics of von Willebrand factor. | J E Sadler | Annu Rev Biochem | 1998 | 9759493 | No |
3952 | 1058 | 1058.0 | 21.76 | 21.8 | The muscular dystrophies. | Alan E H Emery | Lancet | 2002 | 11879882 | No |
3953 | 1058 | 1058.0 | 0.0 | 0.0 | The Physiological Principle of Minimum Work: I. The Vascular System and the Cost of Blood Volume. | C D Murray | Proc Natl Acad Sci U S A | 1926 | 16576980 | Yes |
3954 | 1058 | 1058.0 | 0.0 | 0.0 | On the Absorption of Fluids from the Connective Tissue Spaces. | E H Starling | J Physiol | 1896 | 16992325 | Yes |
3955 | 1058 | 1058.0 | 20.81 | 20.8 | The evolutionary significance of cis-regulatory mutations. | Gregory A Wray | Nat Rev Genet | 2007 | 17304246 | No |
3956 | 1058 | 1058.0 | 77.02 | 77.0 | Head and Neck Cancer. | Laura Q M Chow | N Engl J Med | 2020 | 31893516 | No |
3957 | 2115 | 1057.5 | 82.74 | 41.4 | Comparative aspects of the brain growth spurt. | J Dobbing, J Sands | Early Hum Dev | 1979 | 118862 | Yes |
3958 | 2115 | 1057.5 | 54.27 | 27.1 | Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. | M S Brown, J L Goldstein | Annu Rev Biochem | 1983 | 6311077 | No |
3959 | 2114 | 1057.0 | 85.15 | 42.6 | The aggression questionnaire. | A H Buss, M Perry | J Pers Soc Psychol | 1992 | 1403624 | Yes |
3960 | 1057 | 1057.0 | 31.53 | 31.5 | Comparing evolvability and variability of quantitative traits. | D Houle | Genetics | 1992 | 1732160 | Yes |
3961 | 1057 | 1057.0 | 29.7 | 29.7 | Hepatitis B virus. The major etiology of hepatocellular carcinoma. | R P Beasley | Cancer | 1988 | 2834034 | No |
3962 | 2114 | 1057.0 | 0.0 | 0.0 | Use of glucose oxidase, peroxidase, and O-dianisidine in determination of blood and urinary glucose. | A S Huggett, D A Nixon | Lancet | 1957 | 13464070 | Yes |
3963 | 1057 | 1057.0 | 26.59 | 26.6 | The potential environmental impact of engineered nanomaterials. | Vicki L Colvin | Nat Biotechnol | 2003 | 14520401 | Yes |
3964 | 2113 | 1056.5 | 61.97 | 31.0 | The biochemistry of P-glycoprotein-mediated multidrug resistance. | J A Endicott, V Ling | Annu Rev Biochem | 1989 | 2570548 | No |
3965 | 2113 | 1056.5 | 0.0 | 0.0 | Histochemistry of hepatic phosphatases of a physiologic pH; with special reference to the demonstration of bile canaliculi. | M Wachstein, E Meisel | Am J Clin Pathol | 1957 | 13410831 | Yes |
3966 | 2113 | 1056.5 | 58.47 | 29.2 | The diversity and biogeography of soil bacterial communities. | Noah Fierer, Robert B Jackson | Proc Natl Acad Sci U S A | 2006 | 16407148 | Yes |
3967 | 2113 | 1056.5 | 100.11 | 50.1 | AMPK: guardian of metabolism and mitochondrial homeostasis. | Sébastien Herzig, Reuben J Shaw | Nat Rev Mol Cell Biol | 2018 | 28974774 | No |
3968 | 3169 | 1056.3 | 66.41 | 22.1 | TGF-beta signalling from cell membrane to nucleus through SMAD proteins. | C H Heldin, K Miyazono, P ten Dijke | Nature | 1997 | 9393997 | No |
3969 | 1056 | 1056.0 | 31.95 | 31.9 | Topography of cognition: parallel distributed networks in primate association cortex. | P S Goldman-Rakic | Annu Rev Neurosci | 1988 | 3284439 | No |
3970 | 1056 | 1056.0 | 43.2 | 43.2 | Toward terminological, conceptual, and statistical clarity in the study of mediators and moderators: examples from the child-clinical and pediatric psychology literatures. | G N Holmbeck | J Consult Clin Psychol | 1997 | 9256561 | Yes |
3971 | 1056 | 1056.0 | 21.61 | 21.6 | Alpha-synuclein and neurodegenerative diseases. | M Goedert | Nat Rev Neurosci | 2001 | 11433374 | No |
3972 | 2112 | 1056.0 | 51.73 | 25.9 | Interaction revisited: the difference between two estimates. | Douglas G Altman, J Martin Bland | BMJ | 2003 | 12543843 | No |
3973 | 1056 | 1056.0 | 29.32 | 29.3 | Growing group of extended-spectrum beta-lactamases: the CTX-M enzymes. | R Bonnet | Antimicrob Agents Chemother | 2004 | 14693512 | No |
3974 | 1056 | 1056.0 | 42.71 | 42.7 | Root canal irrigants. | Matthias Zehnder | J Endod | 2006 | 16631834 | No |
3975 | 1056 | 1056.0 | 38.35 | 38.4 | Human milk oligosaccharides: every baby needs a sugar mama. | Lars Bode | Glycobiology | 2012 | 22513036 | No |
3976 | 2111 | 1055.5 | 45.03 | 22.5 | The immunoglobulin superfamily--domains for cell surface recognition. | A F Williams, A N Barclay | Annu Rev Immunol | 1988 | 3289571 | No |
3977 | 2111 | 1055.5 | 36.24 | 18.1 | The growth of mouse bone marrow cells in vitro. | T R Bradley, D Metcalf | Aust J Exp Biol Med Sci | 1966 | 4164182 | Yes |
3978 | 2111 | 1055.5 | 71.74 | 35.9 | Toll-like receptor signaling pathways. | Takumi Kawasaki, Taro Kawai | Front Immunol | 2014 | 25309543 | No |
3979 | 1055 | 1055.0 | 21.56 | 21.6 | The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells. | D Metcalf | Nature | 1989 | 2469962 | No |
3980 | 1055 | 1055.0 | 25.6 | 25.6 | The granulocyte-macrophage colony-stimulating factors. | D Metcalf | Science | 1985 | 2990035 | No |
3981 | 1055 | 1055.0 | 26.25 | 26.2 | The ultrastructural basis of capillary permeability studied with peroxidase as a tracer. | M J Karnovsky | J Cell Biol | 1967 | 6061717 | Yes |
3982 | 1055 | 1055.0 | 29.77 | 29.8 | Determination of total protein. | G L Peterson | Methods Enzymol | 1983 | 6855607 | Yes |
3983 | 1055 | 1055.0 | 23.12 | 23.1 | A cortical-hippocampal system for declarative memory. | H Eichenbaum | Nat Rev Neurosci | 2000 | 11252767 | No |
3984 | 1054 | 1054.0 | 23.91 | 23.9 | The inducible transcription activator NF-kappa B: regulation by distinct protein subunits. | P A Baeuerle | Biochim Biophys Acta | 1991 | 2018779 | No |
3985 | 1054 | 1054.0 | 32.42 | 32.4 | Selective modification of glutathione metabolism. | A Meister | Science | 1983 | 6836290 | Yes |
3986 | 1054 | 1054.0 | 17.0 | 17.0 | T cell anergy. | Ronald H Schwartz | Annu Rev Immunol | 2003 | 12471050 | No |
3987 | 1054 | 1054.0 | 18.0 | 18.0 | TNF/TNFR family members in costimulation of T cell responses. | Tania H Watts | Annu Rev Immunol | 2005 | 15771565 | No |
3988 | 1054 | 1054.0 | 26.21 | 26.2 | Spontaneous low-frequency BOLD signal fluctuations: an fMRI investigation of the resting-state default mode of brain function hypothesis. | Peter Fransson | Hum Brain Mapp | 2005 | 15852468 | Yes |
3989 | 3161 | 1053.7 | 73.27 | 24.4 | STATs in cancer inflammation and immunity: a leading role for STAT3. | Hua Yu, Drew Pardoll, Richard Jove | Nat Rev Cancer | 2009 | 19851315 | No |
3990 | 3160 | 1053.3 | 69.7 | 23.2 | Mitochondria, oxidants, and aging. | Robert S Balaban, Shino Nemoto, Toren Finkel | Cell | 2005 | 15734681 | No |
3991 | 1053 | 1053.0 | 31.37 | 31.4 | Spontaneous dissection of the carotid and vertebral arteries. | W I Schievink | N Engl J Med | 2001 | 11259724 | No |
3992 | 1053 | 1053.0 | 34.17 | 34.2 | Subjective well-being. The science of happiness and a proposal for a national index. | E Diener | Am Psychol | 2000 | 11392863 | Yes |
3993 | 1053 | 1053.0 | 18.04 | 18.0 | The concept of synthetic lethality in the context of anticancer therapy. | William G Kaelin | Nat Rev Cancer | 2005 | 16110319 | No |
3994 | 2105 | 1052.5 | 53.15 | 26.6 | Recent developments in the MAFFT multiple sequence alignment program. | Kazutaka Katoh, Hiroyuki Toh | Brief Bioinform | 2008 | 18372315 | Yes |
3995 | 3157 | 1052.3 | 60.7 | 20.2 | Genetic instabilities in human cancers. | C Lengauer, K W Kinzler, B Vogelstein | Nature | 1998 | 9872311 | No |
3996 | 3157 | 1052.3 | 85.81 | 28.6 | FastTree: computing large minimum evolution trees with profiles instead of a distance matrix. | Morgan N Price, Paramvir S Dehal, Adam P Arkin | Mol Biol Evol | 2009 | 19377059 | Yes |
3997 | 2104 | 1052.0 | 78.74 | 39.4 | Fingerprinting genomes using PCR with arbitrary primers. | J Welsh, M McClelland | Nucleic Acids Res | 1990 | 2259619 | Yes |
3998 | 1052 | 1052.0 | 29.79 | 29.8 | Advanced protein glycosylation in diabetes and aging. | M Brownlee | Annu Rev Med | 1995 | 7598459 | No |
3999 | 1052 | 1052.0 | 25.94 | 25.9 | The sphingomyelin cycle and the second messenger function of ceramide. | Y A Hannun | J Biol Chem | 1994 | 8106344 | No |
4000 | 2104 | 1052.0 | 59.72 | 29.9 | The spread of obesity in a large social network over 32 years. | Nicholas A Christakis, James H Fowler | N Engl J Med | 2007 | 17652652 | Yes |
4001 | 2103 | 1051.5 | 35.43 | 17.7 | The period of susceptibility to the physiological effects of unilateral eye closure in kittens. | D H Hubel, T N Wiesel | J Physiol | 1970 | 5498493 | Yes |
4002 | 2103 | 1051.5 | 42.35 | 21.2 | Autophagy in health and disease: a double-edged sword. | Takahiro Shintani, Daniel J Klionsky | Science | 2004 | 15528435 | No |
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