Unicorn Papers - Top cited papers from PUBMED

No.	Citations	EC_cit	RCR	EC_RCR	Title	Authors	Journal	Year	PMID	Article(?)
1	162851	162851.0	0.0	0.0	Cleavage of structural proteins during the assembly of the head of bacteriophage T4.	U K Laemmli	Nature	1970	5432063	Yes
2	130102	130102.0	0.0	0.0	A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.	M M Bradford	Anal Biochem	1976	942051	Yes
3	192414	48103.5	0.0	0.0	Protein measurement with the Folin phenol reagent.	O H LOWRY, N J ROSEBROUGH, A L FARR, R J RANDALL	J Biol Chem	1951	14907713	Yes
4	79861	39930.5	2264.27	1132.1	Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.	K J Livak, T D Schmittgen	Methods	2001	11846609	Yes
5	39175	39175.0	1515.58	1515.6	A short history of SHELX.	George M Sheldrick	Acta Crystallogr A	2008	18156677	Yes
6	26049	26049.0	1078.57	1078.6	Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.	T Mosmann	J Immunol Methods	1983	6606682	Yes
7	23098	23098.0	0.0	0.0	Detection of specific sequences among DNA fragments separated by gel electrophoresis.	E M Southern	J Mol Biol	1975	1195397	Yes
8	45238	22619.0	1834.49	917.2	Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.	P Chomczynski, N Sacchi	Anal Biochem	1987	2440339	Yes
9	21708	21708.0	530.26	530.3	MicroRNAs: genomics, biogenesis, mechanism, and function.	David P Bartel	Cell	2004	14744438	No
10	21356	21356.0	0.0	0.0	The assessment and analysis of handedness: the Edinburgh inventory.	R C Oldfield	Neuropsychologia	1971	5146491	Yes
11	18602	18602.0	494.02	494.0	MUSCLE: multiple sequence alignment with high accuracy and high throughput.	Robert C Edgar	Nucleic Acids Res	2004	15034147	Yes
12	18591	18591.0	480.17	480.2	A new mathematical model for relative quantification in real-time RT-PCR.	M W Pfaffl	Nucleic Acids Res	2001	11328886	Yes
13	17084	17084.0	0.0	0.0	A rating scale for depression.	M HAMILTON	J Neurol Neurosurg Psychiatry	1960	14399272	Yes
14	47413	15804.3	0.0	0.0	"Mini-mental state". A practical method for grading the cognitive state of patients for the clinician.	M F Folstein, S E Folstein, P R McHugh	J Psychiatr Res	1975	1202204	Yes
15	31007	15503.5	1157.79	578.9	The neighbor-joining method: a new method for reconstructing phylogenetic trees.	N Saitou, M Nei	Mol Biol Evol	1987	3447015	Yes
16	44874	14958.0	0.0	0.0	DNA sequencing with chain-terminating inhibitors.	F Sanger, S Nicklen, A R Coulson	Proc Natl Acad Sci U S A	1977	271968	Yes
17	14082	14082.0	0.0	0.0	The use of lead citrate at high pH as an electron-opaque stain in electron microscopy.	E S REYNOLDS	J Cell Biol	1963	13986422	Yes
18	13744	13744.0	511.99	512.0	CONFIDENCE LIMITS ON PHYLOGENIES: AN APPROACH USING THE BOOTSTRAP.	Joseph Felsenstein	Evolution	1985	28561359	Yes
19	27196	13598.0	1637.26	818.6	Statistical methods for assessing agreement between two methods of clinical measurement.	J M Bland, D G Altman	Lancet	1986	2868172	Yes
20	27053	13526.5	1069.92	535.0	Hallmarks of cancer: the next generation.	Douglas Hanahan, Robert A Weinberg	Cell	2011	21376230	No
21	13518	13518.0	408.07	408.1	Atherosclerosis--an inflammatory disease.	R Ross	N Engl J Med	1999	9887164	No
22	13056	13056.0	0.0	0.0	Tissue sulfhydryl groups.	G L ELLMAN	Arch Biochem Biophys	1959	13650640	Yes
23	12958	12958.0	573.87	573.9	A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences.	M Kimura	J Mol Evol	1980	7463489	Yes
24	25278	12639.0	0.0	0.0	The measurement of observer agreement for categorical data.	J R Landis, G G Koch	Biometrics	1977	843571	Yes
25	37485	12495.0	1270.7	423.6	CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.	J D Thompson, D G Higgins, T J Gibson	Nucleic Acids Res	1994	7984417	Yes
26	12435	12435.0	548.53	548.5	Density-functional exchange-energy approximation with correct asymptotic behavior.	Becke	Phys Rev A Gen Phys	1988	9900728	Yes
27	11771	11771.0	344.88	344.9	MicroRNAs: target recognition and regulatory functions.	David P Bartel	Cell	2009	19167326	No
28	35192	11730.7	0.0	0.0	Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.	H Towbin, T Staehelin, J Gordon	Proc Natl Acad Sci U S A	1979	388439	Yes
29	11672	11672.0	0.0	0.0	High resolution two-dimensional electrophoresis of proteins.	P H O'Farrell	J Biol Chem	1975	236308	Yes
30	22201	11100.5	0.0	0.0	A rapid method of total lipid extraction and purification.	E G BLIGH, W J DYER	Can J Biochem Physiol	1959	13671378	Yes
31	10775	10775.0	568.08	568.1	A power primer.	J Cohen	Psychol Bull	1992	19565683	Yes
32	21339	10669.5	975.4	487.7	Meta-analysis in clinical trials.	R DerSimonian, N Laird	Control Clin Trials	1986	3802833	Yes
33	10451	10451.0	0.0	0.0	DISC ELECTROPHORESIS. II. METHOD AND APPLICATION TO HUMAN SERUM PROTEINS.	B J DAVIS	Ann N Y Acad Sci	1964	14240539	Yes
34	20626	10313.0	1050.5	525.2	The hospital anxiety and depression scale.	A S Zigmond, R P Snaith	Acta Psychiatr Scand	1983	6880820	Yes
35	9885	9885.0	0.0	0.0	A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid.	K BURTON	Biochem J	1956	13293190	Yes
36	29520	9840.0	0.0	0.0	A simple method for the isolation and purification of total lipides from animal tissues.	J FOLCH, M LEES, G H SLOANE STANLEY	J Biol Chem	1957	13428781	Yes
37	9811	9811.0	320.53	320.5	Projector augmented-wave method.	Blöchl	Phys Rev B Condens Matter	1994	9976227	Yes
38	18940	9470.0	449.43	224.7	Coot: model-building tools for molecular graphics.	Paul Emsley, Kevin Cowtan	Acta Crystallogr D Biol Crystallogr	2004	15572765	Yes
39	18810	9405.0	1027.28	513.6	The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection.	J E Ware, C D Sherbourne	Med Care	1992	1593914	Yes
40	9324	9324.0	432.57	432.6	Structure validation in chemical crystallography.	Anthony L Spek	Acta Crystallogr D Biol Crystallogr	2009	19171970	Yes
41	9180	9180.0	450.81	450.8	Catalase in vitro.	H Aebi	Methods Enzymol	1984	6727660	Yes
42	44746	8949.2	1513.32	302.7	Basic local alignment search tool.	S F Altschul, W Gish, W Miller, E W Myers, D J Lipman	J Mol Biol	1990	2231712	Yes
43	8857	8857.0	0.0	0.0	The genetics of Caenorhabditis elegans.	S Brenner	Genetics	1974	4366476	Yes
44	17294	8647.0	505.86	252.9	Fast and accurate short read alignment with Burrows-Wheeler transform.	Heng Li, Richard Durbin	Bioinformatics	2009	19451168	Yes
45	8641	8641.0	533.62	533.6	RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies.	Alexandros Stamatakis	Bioinformatics	2014	24451623	Yes
46	25455	8485.0	899.81	299.9	Generalized Gradient Approximation Made Simple.	Perdew, Burke, Ernzerhof	Phys Rev Lett	1996	10062328	Yes
47	8407	8407.0	0.0	0.0	Phosphorus assay in column chromatography.	G R BARTLETT	J Biol Chem	1959	13641241	Yes
48	8364	8364.0	284.66	284.7	The Psychophysics Toolbox.	D H Brainard	Spat Vis	1997	9176952	Yes
49	16249	8124.5	396.39	198.2	[20] Processing of X-ray diffraction data collected in oscillation mode.	Zbyszek Otwinowski, Wladek Minor	Methods Enzymol	1997	27799103	Yes
50	8124	8124.0	257.37	257.4	XDS.	Wolfgang Kabsch	Acta Crystallogr D Biol Crystallogr	2010	20124692	Yes
51	8094	8094.0	323.1	323.1	Search and clustering orders of magnitude faster than BLAST.	Robert C Edgar	Bioinformatics	2010	20709691	Yes
52	7947	7947.0	331.86	331.9	Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS).	J F Kurtzke	Neurology	1983	6685237	Yes
53	15615	7807.5	579.0	289.5	A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.	A P Feinberg, B Vogelstein	Anal Biochem	1983	6312838	Yes
54	7695	7695.0	181.37	181.4	Mfold web server for nucleic acid folding and hybridization prediction.	Michael Zuker	Nucleic Acids Res	2003	12824337	Yes
55	7643	7643.0	265.84	265.8	Studies on transformation of Escherichia coli with plasmids.	D Hanahan	J Mol Biol	1983	6345791	Yes
56	7616	7616.0	170.45	170.4	Linear models and empirical bayes methods for assessing differential expression in microarray experiments.	Gordon K Smyth	Stat Appl Genet Mol Biol	2004	16646809	Yes
57	7615	7615.0	225.12	225.1	RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models.	Alexandros Stamatakis	Bioinformatics	2006	16928733	Yes
58	22647	7549.0	1024.97	341.7	Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density.	Lee, Yang, Parr	Phys Rev B Condens Matter	1988	9944570	Yes
59	7548	7548.0	0.0	0.0	Self-efficacy: toward a unifying theory of behavioral change.	A Bandura	Psychol Rev	1977	847061	Yes
60	7398	7398.0	353.24	353.2	A new method for measuring daytime sleepiness: the Epworth sleepiness scale.	M W Johns	Sleep	1991	1798888	Yes
61	14780	7390.0	595.75	297.9	Fast gapped-read alignment with Bowtie 2.	Ben Langmead, Steven L Salzberg	Nat Methods	2012	22388286	Yes
62	14778	7389.0	799.24	399.6	The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations.	R M Baron, D A Kenny	J Pers Soc Psychol	1986	3806354	Yes
63	7369	7369.0	253.15	253.2	Evolutionary trees from DNA sequences: a maximum likelihood approach.	J Felsenstein	J Mol Evol	1981	7288891	Yes
64	14714	7357.0	350.19	175.1	The hallmarks of cancer.	D Hanahan, R A Weinberg	Cell	2000	10647931	No
65	14271	7135.5	491.1	245.6	A simple method for displaying the hydropathic character of a protein.	J Kyte, R F Doolittle	J Mol Biol	1982	7108955	Yes
66	14224	7112.0	466.79	233.4	Quantifying heterogeneity in a meta-analysis.	Julian P T Higgins, Simon G Thompson	Stat Med	2002	12111919	Yes
67	7107	7107.0	261.75	261.8	The pathogenesis of atherosclerosis: a perspective for the 1990s.	R Ross	Nature	1993	8479518	No
68	6986	6986.0	248.71	248.7	Vitamin D deficiency.	Michael F Holick	N Engl J Med	2007	17634462	No
69	6813	6813.0	0.0	0.0	Improvements in epoxy resin embedding methods.	J H LUFT	J Biophys Biochem Cytol	1961	13764136	Yes
70	6766	6766.0	156.99	157.0	The functions of animal microRNAs.	Victor Ambros	Nature	2004	15372042	No
71	6591	6591.0	221.43	221.4	Integrins: versatility, modulation, and signaling in cell adhesion.	R O Hynes	Cell	1992	1555235	No
72	6581	6581.0	280.01	280.0	Banting lecture 1988. Role of insulin resistance in human disease.	G M Reaven	Diabetes	1988	3056758	No
73	6566	6566.0	0.0	0.0	On the origin of cancer cells.	O WARBURG	Science	1956	13298683	Yes
74	13067	6533.5	322.83	161.4	Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.	Kazutoshi Takahashi, Shinya Yamanaka	Cell	2006	16904174	Yes
75	13029	6514.5	304.89	152.4	Processing of X-ray diffraction data collected in oscillation mode.	Z Otwinowski, W Minor	Methods Enzymol	1997	27754618	Yes
76	6510	6510.0	370.32	370.3	Psychophysical bases of perceived exertion.	G A Borg	Med Sci Sports Exerc	1982	7154893	Yes
77	12888	6444.0	0.0	0.0	The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis.	K Weber, M Osborn	J Biol Chem	1969	5806584	Yes
78	25667	6416.8	901.47	225.4	Measuring inconsistency in meta-analyses.	Julian P T Higgins, Simon G Thompson, Jonathan J Deeks, Douglas G Altman	BMJ	2003	12958120	No
79	6379	6379.0	561.17	561.2	Crystal structure refinement with SHELXL.	George M Sheldrick	Acta Crystallogr C Struct Chem	2015	25567568	Yes
80	6299	6299.0	193.25	193.2	Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus.	M C Hochberg	Arthritis Rheum	1997	9324032	Yes
81	12582	6291.0	398.92	199.5	Efficient iterative schemes for ab initio total-energy calculations using a plane-wave basis set.	Kresse, Furthmüller	Phys Rev B Condens Matter	1996	9984901	Yes
82	18835	6278.3	567.18	189.1	Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources.	Da Wei Huang, Brad T Sherman, Richard A Lempicki	Nat Protoc	2009	19131956	Yes
83	12554	6277.0	349.09	174.5	MrBayes 3: Bayesian phylogenetic inference under mixed models.	Fredrik Ronquist, John P Huelsenbeck	Bioinformatics	2003	12912839	Yes
84	6227	6227.0	0.0	0.0	COPPER ENZYMES IN ISOLATED CHLOROPLASTS. POLYPHENOLOXIDASE IN BETA VULGARIS.	D I Arnon	Plant Physiol	1949	16654194	Yes
85	18530	6176.7	538.35	179.5	VMD: visual molecular dynamics.	W Humphrey, A Dalke, K Schulten	J Mol Graph	1996	8744570	Yes
86	6148	6148.0	199.03	199.0	TreeView: an application to display phylogenetic trees on personal computers.	R D Page	Comput Appl Biosci	1996	8902363	Yes
87	6137	6137.0	186.57	186.6	Statistical method for testing the neutral mutation hypothesis by DNA polymorphism.	F Tajima	Genetics	1989	2513255	Yes
88	42915	6130.7	1265.57	180.8	Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.	S F Altschul, T L Madden, A A Schäffer, J Zhang, Z Zhang, W Miller, D J Lipman	Nucleic Acids Res	1997	9254694	No
89	6112	6112.0	0.0	0.0	Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.	A Böyum	Scand J Clin Lab Invest Suppl	1968	4179068	Yes
90	6048	6048.0	203.04	203.0	AFNI: software for analysis and visualization of functional magnetic resonance neuroimages.	R W Cox	Comput Biomed Res	1996	8812068	Yes
91	24088	6022.0	1094.67	273.7	A new method of classifying prognostic comorbidity in longitudinal studies: development and validation.	M E Charlson, P Pompei, K L Ales, C R MacKenzie	J Chronic Dis	1987	3558716	Yes
92	5990	5990.0	199.33	199.3	Semiempirical GGA-type density functional constructed with a long-range dispersion correction.	Stefan Grimme	J Comput Chem	2006	16955487	Yes
93	5979	5979.0	144.08	144.1	Chromatin modifications and their function.	Tony Kouzarides	Cell	2007	17320507	No
94	11778	5889.0	283.02	141.5	Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana.	S J Clough, A F Bent	Plant J	1998	10069079	Yes
95	5820	5820.0	238.64	238.6	Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.	P S Thomas	Proc Natl Acad Sci U S A	1980	6159641	Yes
96	5820	5820.0	160.61	160.6	PAML 4: phylogenetic analysis by maximum likelihood.	Ziheng Yang	Mol Biol Evol	2007	17483113	Yes
97	5690	5690.0	223.34	223.3	"Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A.	W N Burnette	Anal Biochem	1981	6266278	Yes
98	22745	5686.2	878.11	219.5	Bias in meta-analysis detected by a simple, graphical test.	M Egger, G Davey Smith, M Schneider, C Minder	BMJ	1997	9310563	Yes
99	11295	5647.5	346.24	173.1	Analyzing real-time PCR data by the comparative C(T) method.	Thomas D Schmittgen, Kenneth J Livak	Nat Protoc	2008	18546601	Yes
100	5610	5610.0	0.0	0.0	A simplification of the protein assay method of Lowry et al. which is more generally applicable.	G L Peterson	Anal Biochem	1977	603028	Yes
101	5596	5596.0	161.37	161.4	Fast robust automated brain extraction.	Stephen M Smith	Hum Brain Mapp	2002	12391568	No
102	5506	5506.0	0.0	0.0	Solvent content of protein crystals.	B W Matthews	J Mol Biol	1968	5700707	Yes
103	5499	5499.0	188.53	188.5	The VideoToolbox software for visual psychophysics: transforming numbers into movies.	D G Pelli	Spat Vis	1997	9176953	Yes
104	16167	5389.0	706.69	235.6	NIH Image to ImageJ: 25 years of image analysis.	Caroline A Schneider, Wayne S Rasband, Kevin W Eliceiri	Nat Methods	2012	22930834	No
105	10748	5374.0	408.9	204.4	Sequencing end-labeled DNA with base-specific chemical cleavages.	A M Maxam, W Gilbert	Methods Enzymol	1980	6246368	Yes
106	5323	5323.0	219.93	219.9	Ethical guidelines for investigations of experimental pain in conscious animals.	Manfred Zimmermann	Pain	1983	6877845	No
107	5306	5306.0	200.34	200.3	The blockade of immune checkpoints in cancer immunotherapy.	Drew M Pardoll	Nat Rev Cancer	2012	22437870	No
108	5248	5248.0	320.0	320.0	Comparative fit indexes in structural models.	P M Bentler	Psychol Bull	1990	2320703	Yes
109	5243	5243.0	0.0	0.0	A low-viscosity epoxy resin embedding medium for electron microscopy.	A R Spurr	J Ultrastruct Res	1969	4887011	Yes
110	5190	5190.0	172.03	172.0	Canonical dynamics: Equilibrium phase-space distributions.	Hoover	Phys Rev A Gen Phys	1985	9895674	Yes
111	15552	5184.0	0.0	0.0	Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.	W T Friedewald, R I Levy, D S Fredrickson	Clin Chem	1972	4337382	Yes
112	15370	5123.3	574.83	191.6	A new generation of Ca2+ indicators with greatly improved fluorescence properties.	G Grynkiewicz, M Poenie, R Y Tsien	J Biol Chem	1985	3838314	Yes
113	5093	5093.0	0.0	0.0	Evaluation of survival data and two new rank order statistics arising in its consideration.	N Mantel	Cancer Chemother Rep	1966	5910392	Yes
114	5080	5080.0	114.24	114.2	Integrins: bidirectional, allosteric signaling machines.	Richard O Hynes	Cell	2002	12297042	No
115	5053	5053.0	224.92	224.9	Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses.	Andreas Stang	Eur J Epidemiol	2010	20652370	Yes
116	5041	5041.0	203.73	203.7	The role of protein kinase C in cell surface signal transduction and tumour promotion.	Y Nishizuka	Nature	1984	6232463	No
117	20126	5031.5	983.47	245.9	Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.	David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman	PLoS Med	2009	19621072	No
118	10006	5003.0	228.18	114.1	KEGG: kyoto encyclopedia of genes and genomes.	M Kanehisa, S Goto	Nucleic Acids Res	2000	10592173	Yes
119	4974	4974.0	0.0	0.0	Tumor angiogenesis: therapeutic implications.	J Folkman	N Engl J Med	1971	4938153	No
120	4970	4970.0	127.3	127.3	Inflammation in atherosclerosis.	Peter Libby	Nature	2002	12490960	No
121	9860	4930.0	0.0	0.0	A rapid alkaline extraction procedure for screening recombinant plasmid DNA.	H C Birnboim, J Doly	Nucleic Acids Res	1979	388356	Yes
122	4930	4930.0	212.68	212.7	Density-functional approximation for the correlation energy of the inhomogeneous electron gas.	Perdew	Phys Rev B Condens Matter	1986	9938299	Yes
123	4914	4914.0	153.04	153.0	Angiogenesis in cancer, vascular, rheumatoid and other disease.	J Folkman	Nat Med	1995	7584949	No
124	4895	4895.0	192.65	192.7	The Clinical Dementia Rating (CDR): current version and scoring rules.	J C Morris	Neurology	1993	8232972	Yes
125	4887	4887.0	135.72	135.7	Inflammation, atherosclerosis, and coronary artery disease.	Göran K Hansson	N Engl J Med	2005	15843671	No
126	4885	4885.0	149.73	149.7	Apoptosis: a review of programmed cell death.	Susan Elmore	Toxicol Pathol	2007	17562483	No
127	4833	4833.0	118.95	119.0	p53, the cellular gatekeeper for growth and division.	A J Levine	Cell	1997	9039259	No
128	4826	4826.0	0.0	0.0	Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.	J R Vane	Nat New Biol	1971	5284360	Yes
129	4790	4790.0	133.34	133.3	Biochemistry and molecular cell biology of diabetic complications.	M Brownlee	Nature	2001	11742414	Yes
130	9485	4742.5	0.0	0.0	Intraclass correlations: uses in assessing rater reliability.	P E Shrout, J L Fleiss	Psychol Bull	1979	18839484	No
131	9466	4733.0	250.77	125.4	A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood.	Stéphane Guindon, Olivier Gascuel	Syst Biol	2003	14530136	Yes
132	9463	4731.5	262.3	131.2	MRBAYES: Bayesian inference of phylogenetic trees.	J P Huelsenbeck, F Ronquist	Bioinformatics	2001	11524383	Yes
133	4705	4705.0	0.0	0.0	Development of a rating scale for primary depressive illness.	M Hamilton	Br J Soc Clin Psychol	1967	6080235	Yes
134	9402	4701.0	307.52	153.8	MODELTEST: testing the model of DNA substitution.	D Posada, K A Crandall	Bioinformatics	1998	9918953	Yes
135	4698	4698.0	94.99	95.0	BLAT--the BLAST-like alignment tool.	W James Kent	Genome Res	2002	11932250	Yes
136	9381	4690.5	237.07	118.5	Dendritic cells and the control of immunity.	J Banchereau, R M Steinman	Nature	1998	9521319	No
137	9367	4683.5	0.0	0.0	Continuous cultures of fused cells secreting antibody of predefined specificity.	G Köhler, C Milstein	Nature	1975	1172191	Yes
138	14042	4680.7	711.01	237.0	Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2.	Michael I Love, Wolfgang Huber, Simon Anders	Genome Biol	2014	25516281	Yes
139	4639	4639.0	0.0	0.0	The assessment of anxiety states by rating.	M HAMILTON	Br J Med Psychol	1959	13638508	Yes
140	9247	4623.5	0.0	0.0	Statistical aspects of the analysis of data from retrospective studies of disease.	N MANTEL, W HAENSZEL	J Natl Cancer Inst	1959	13655060	Yes
141	4616	4616.0	128.55	128.6	Free radicals in the physiological control of cell function.	Wulf Dröge	Physiol Rev	2002	11773609	No
142	23066	4613.2	726.23	145.2	The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools.	J D Thompson, T J Gibson, F Plewniak, F Jeanmougin, D G Higgins	Nucleic Acids Res	1997	9396791	Yes
143	9216	4608.0	0.0	0.0	Prediction of creatinine clearance from serum creatinine.	D W Cockcroft, M H Gault	Nephron	1976	1244564	Yes
144	4588	4588.0	136.62	136.6	Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm.	T A Springer	Cell	1994	7507411	No
145	9163	4581.5	403.96	202.0	The meaning and use of the area under a receiver operating characteristic (ROC) curve.	J A Hanley, B J McNeil	Radiology	1982	7063747	Yes
146	9114	4557.0	227.32	113.7	One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products.	K A Datsenko, B L Wanner	Proc Natl Acad Sci U S A	2000	10829079	Yes
147	9111	4555.5	479.52	239.8	MAFFT multiple sequence alignment software version 7: improvements in performance and usability.	Kazutaka Katoh, Daron M Standley	Mol Biol Evol	2013	23329690	Yes
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3334	1618	809.0	59.47	29.7	The acute phase response.	H Baumann, J Gauldie	Immunol Today	1994	7512342	No
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3336	809	809.0	18.55	18.6	The advantages and disadvantages of being polyploid.	Luca Comai	Nat Rev Genet	2005	16304599	No
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Volume 6, February 2021