Unicorn Papers
Top ‱ cited papers from PUBMED
Unicorn Papers are based on an equal contribution (EC) citation model in which the total number of citations had been divided by the number of the authorsCurrently, the list contains 3328 papers with ECcit ≥ 792.0
‱ - permyriad,
, literally meaning "for (every) myriad (ten thousand)"
Volume 5, January 2021
| No. | Citations | ECcit | RCR | ECRCR | Title | Authors | Journal | Year | PMID | Article(?) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 160477 | 160477.0 | 0.0 | 0.0 | Cleavage of structural proteins during the assembly of the head of bacteriophage T4. | U K Laemmli | Nature | 1970 | 5432063 | Yes |
| 2 | 129599 | 129599.0 | 0.0 | 0.0 | A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. | M M Bradford | Anal. Biochem. | 1976 | 942051 | Yes |
| 3 | 191141 | 47785.2 | 0.0 | 0.0 | Protein measurement with the Folin phenol reagent. | O H LOWRY, N J ROSEBROUGH, A L FARR, R J RANDALL | J. Biol. Chem. | 1951 | 14907713 | Yes |
| 4 | 77320 | 38660.0 | 2211.76 | 1105.9 | Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. | K J Livak, T D Schmittgen | Methods | 2001 | 11846609 | Yes |
| 5 | 38954 | 38954.0 | 1531.35 | 1531.3 | A short history of SHELX. | George M Sheldrick | Acta Crystallogr., A, Found. Crystallogr. | 2008 | 18156677 | Yes |
| 6 | 25300 | 25300.0 | 1056.68 | 1056.7 | Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. | T Mosmann | J. Immunol. Methods | 1983 | 6606682 | Yes |
| 7 | 22924 | 22924.0 | 0.0 | 0.0 | Detection of specific sequences among DNA fragments separated by gel electrophoresis. | E M Southern | J. Mol. Biol. | 1975 | 1195397 | Yes |
| 8 | 45099 | 22549.5 | 1846.05 | 923.0 | Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. | P Chomczynski, N Sacchi | Anal. Biochem. | 1987 | 2440339 | Yes |
| 9 | 21080 | 21080.0 | 522.16 | 522.2 | MicroRNAs: genomics, biogenesis, mechanism, and function. | David P Bartel | Cell | 2004 | 14744438 | No |
| 10 | 20828 | 20828.0 | 0.0 | 0.0 | The assessment and analysis of handedness: the Edinburgh inventory. | R C Oldfield | Neuropsychologia | 1971 | 5146491 | Yes |
| 11 | 18054 | 18054.0 | 485.62 | 485.6 | MUSCLE: multiple sequence alignment with high accuracy and high throughput. | Robert C Edgar | Nucleic Acids Res. | 2004 | 15034147 | Yes |
| 12 | 18160 | 18160.0 | 473.21 | 473.2 | A new mathematical model for relative quantification in real-time RT-PCR. | M W Pfaffl | Nucleic Acids Res. | 2001 | 11328886 | Yes |
| 13 | 16825 | 16825.0 | 0.0 | 0.0 | A rating scale for depression. | M HAMILTON | J. Neurol. Neurosurg. Psychiatry | 1960 | 14399272 | Yes |
| 14 | 46723 | 15574.3 | 0.0 | 0.0 | "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. | M F Folstein, S E Folstein, P R McHugh | J Psychiatr Res | 1975 | 1202204 | Yes |
| 15 | 30655 | 15327.5 | 1154.07 | 577.0 | The neighbor-joining method: a new method for reconstructing phylogenetic trees. | N Saitou, M Nei | Mol. Biol. Evol. | 1987 | 3447015 | Yes |
| 16 | 44750 | 14916.7 | 0.0 | 0.0 | DNA sequencing with chain-terminating inhibitors. | F Sanger, S Nicklen, A R Coulson | Proc. Natl. Acad. Sci. U.S.A. | 1977 | 271968 | Yes |
| 17 | 13940 | 13940.0 | 0.0 | 0.0 | The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. | E S REYNOLDS | J. Cell Biol. | 1963 | 13986422 | Yes |
| 18 | 12287 | 12287.0 | 467.24 | 467.2 | CONFIDENCE LIMITS ON PHYLOGENIES: AN APPROACH USING THE BOOTSTRAP. | Joseph Felsenstein | Evolution | 1985 | 28561359 | Yes |
| 19 | 27050 | 13525.0 | 1639.62 | 819.8 | Statistical methods for assessing agreement between two methods of clinical measurement. | J M Bland, D G Altman | Lancet | 1986 | 2868172 | Yes |
| 20 | 25595 | 12797.5 | 1038.15 | 519.1 | Hallmarks of cancer: the next generation. | Douglas Hanahan, Robert A Weinberg | Cell | 2011 | 21376230 | No |
| 21 | 13366 | 13366.0 | 407.3 | 407.3 | Atherosclerosis--an inflammatory disease. | R Ross | N. Engl. J. Med. | 1999 | 9887164 | No |
| 22 | 12667 | 12667.0 | 0.0 | 0.0 | Tissue sulfhydryl groups. | G L ELLMAN | Arch. Biochem. Biophys. | 1959 | 13650640 | Yes |
| 23 | 12772 | 12772.0 | 573.11 | 573.1 | A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences. | M Kimura | J. Mol. Evol. | 1980 | 7463489 | Yes |
| 24 | 25025 | 12512.5 | 0.0 | 0.0 | The measurement of observer agreement for categorical data. | J R Landis, G G Koch | Biometrics | 1977 | 843571 | Yes |
| 25 | 37163 | 12387.7 | 1264.78 | 421.6 | CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. | J D Thompson, D G Higgins, T J Gibson | Nucleic Acids Res. | 1994 | 7984417 | Yes |
| 26 | 12248 | 12248.0 | 545.04 | 545.0 | Density-functional exchange-energy approximation with correct asymptotic behavior. | Becke | Phys Rev A Gen Phys | 1988 | 9900728 | Yes |
| 27 | 11362 | 11362.0 | 340.5 | 340.5 | MicroRNAs: target recognition and regulatory functions. | David P Bartel | Cell | 2009 | 19167326 | No |
| 28 | 35041 | 11680.3 | 0.0 | 0.0 | Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. | H Towbin, T Staehelin, J Gordon | Proc. Natl. Acad. Sci. U.S.A. | 1979 | 388439 | Yes |
| 29 | 11605 | 11605.0 | 0.0 | 0.0 | High resolution two-dimensional electrophoresis of proteins. | P H O'Farrell | J. Biol. Chem. | 1975 | 236308 | Yes |
| 30 | 21633 | 10816.5 | 0.0 | 0.0 | A rapid method of total lipid extraction and purification. | E G BLIGH, W J DYER | Can J Biochem Physiol | 1959 | 13671378 | Yes |
| 31 | 10617 | 10617.0 | 563.05 | 563.0 | A power primer. | J Cohen | Psychol Bull | 1992 | 19565683 | Yes |
| 32 | 20893 | 10446.5 | 960.3 | 480.1 | Meta-analysis in clinical trials. | R DerSimonian, N Laird | Control Clin Trials | 1986 | 3802833 | Yes |
| 33 | 10223 | 10223.0 | 0.0 | 0.0 | DISC ELECTROPHORESIS. II. METHOD AND APPLICATION TO HUMAN SERUM PROTEINS. | B J DAVIS | Ann. N. Y. Acad. Sci. | 1964 | 14240539 | Yes |
| 34 | 20186 | 10093.0 | 1039.73 | 519.9 | The hospital anxiety and depression scale. | A S Zigmond, R P Snaith | Acta Psychiatr Scand | 1983 | 6880820 | Yes |
| 35 | 9712 | 9712.0 | 0.0 | 0.0 | A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. | K BURTON | Biochem. J. | 1956 | 13293190 | Yes |
| 36 | 29188 | 9729.3 | 0.0 | 0.0 | A simple method for the isolation and purification of total lipides from animal tissues. | J FOLCH, M LEES, G H SLOANE STANLEY | J. Biol. Chem. | 1957 | 13428781 | Yes |
| 37 | 9675 | 9675.0 | 318.04 | 318.0 | Projector augmented-wave method. | Blöchl | Phys. Rev., B Condens. Matter | 1994 | 9976227 | Yes |
| 38 | 18472 | 9236.0 | 445.06 | 222.5 | Coot: model-building tools for molecular graphics. | Paul Emsley, Kevin Cowtan | Acta Crystallogr. D Biol. Crystallogr. | 2004 | 15572765 | Yes |
| 39 | 18683 | 9341.5 | 1025.16 | 512.6 | The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. | J E Ware, C D Sherbourne | Med Care | 1992 | 1593914 | Yes |
| 40 | 9289 | 9289.0 | 439.33 | 439.3 | Structure validation in chemical crystallography. | Anthony L Spek | Acta Crystallogr. D Biol. Crystallogr. | 2009 | 19171970 | Yes |
| 41 | 8838 | 8838.0 | 439.73 | 439.7 | Catalase in vitro. | H Aebi | Meth. Enzymol. | 1984 | 6727660 | Yes |
| 42 | 43991 | 8798.2 | 1495.47 | 299.1 | Basic local alignment search tool. | S F Altschul, W Gish, W Miller, E W Myers, D J Lipman | J. Mol. Biol. | 1990 | 2231712 | Yes |
| 43 | 8677 | 8677.0 | 0.0 | 0.0 | The genetics of Caenorhabditis elegans. | S Brenner | Genetics | 1974 | 4366476 | Yes |
| 44 | 16646 | 8323.0 | 497.42 | 248.7 | Fast and accurate short read alignment with Burrows-Wheeler transform. | Heng Li, Richard Durbin | Bioinformatics | 2009 | 19451168 | Yes |
| 45 | 7708 | 7708.0 | 494.03 | 494.0 | RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies. | Alexandros Stamatakis | Bioinformatics | 2014 | 24451623 | Yes |
| 46 | 25063 | 8354.3 | 891.33 | 297.1 | Generalized Gradient Approximation Made Simple. | Perdew, Burke, Ernzerhof | Phys. Rev. Lett. | 1996 | 10062328 | Yes |
| 47 | 8375 | 8375.0 | 0.0 | 0.0 | Phosphorus assay in column chromatography. | G R BARTLETT | J. Biol. Chem. | 1959 | 13641241 | Yes |
| 48 | 8207 | 8207.0 | 282.47 | 282.5 | The Psychophysics Toolbox. | D H Brainard | Spat Vis | 1997 | 9176952 | Yes |
| 49 | 15217 | 7608.5 | 372.69 | 186.3 | [20] Processing of X-ray diffraction data collected in oscillation mode. | Zbyszek Otwinowski, Wladek Minor | Meth. Enzymol. | 1997 | 27799103 | Yes |
| 50 | 7836 | 7836.0 | 254.31 | 254.3 | XDS. | Wolfgang Kabsch | Acta Crystallogr. D Biol. Crystallogr. | 2010 | 20124692 | Yes |
| 51 | 7819 | 7819.0 | 319.16 | 319.2 | Search and clustering orders of magnitude faster than BLAST. | Robert C Edgar | Bioinformatics | 2010 | 20709691 | Yes |
| 52 | 7809 | 7809.0 | 330.72 | 330.7 | Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). | J F Kurtzke | Neurology | 1983 | 6685237 | Yes |
| 53 | 15515 | 7757.5 | 580.74 | 290.4 | A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. | A P Feinberg, B Vogelstein | Anal. Biochem. | 1983 | 6312838 | Yes |
| 54 | 7564 | 7564.0 | 180.74 | 180.7 | Mfold web server for nucleic acid folding and hybridization prediction. | Michael Zuker | Nucleic Acids Res. | 2003 | 12824337 | Yes |
| 55 | 7545 | 7545.0 | 265.28 | 265.3 | Studies on transformation of Escherichia coli with plasmids. | D Hanahan | J. Mol. Biol. | 1983 | 6345791 | Yes |
| 56 | 7521 | 7521.0 | 171.0 | 171.0 | Linear models and empirical bayes methods for assessing differential expression in microarray experiments. | Gordon K Smyth | Stat Appl Genet Mol Biol | 2004 | 16646809 | Yes |
| 57 | 7325 | 7325.0 | 219.59 | 219.6 | RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. | Alexandros Stamatakis | Bioinformatics | 2006 | 16928733 | Yes |
| 58 | 22292 | 7430.7 | 1017.07 | 339.0 | Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density. | Lee, Yang, Parr | Phys. Rev., B Condens. Matter | 1988 | 9944570 | Yes |
| 59 | 7471 | 7471.0 | 0.0 | 0.0 | Self-efficacy: toward a unifying theory of behavioral change. | A Bandura | Psychol Rev | 1977 | 847061 | Yes |
| 60 | 7236 | 7236.0 | 347.91 | 347.9 | A new method for measuring daytime sleepiness: the Epworth sleepiness scale. | M W Johns | Sleep | 1991 | 1798888 | Yes |
| 61 | 13974 | 6987.0 | 580.62 | 290.3 | Fast gapped-read alignment with Bowtie 2. | Ben Langmead, Steven L Salzberg | Nat. Methods | 2012 | 22388286 | Yes |
| 62 | 14675 | 7337.5 | 800.94 | 400.5 | The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. | R M Baron, D A Kenny | J Pers Soc Psychol | 1986 | 3806354 | Yes |
| 63 | 7277 | 7277.0 | 252.04 | 252.0 | Evolutionary trees from DNA sequences: a maximum likelihood approach. | J Felsenstein | J. Mol. Evol. | 1981 | 7288891 | Yes |
| 64 | 14390 | 7195.0 | 346.94 | 173.5 | The hallmarks of cancer. | D Hanahan, R A Weinberg | Cell | 2000 | 10647931 | No |
| 65 | 14112 | 7056.0 | 493.52 | 246.8 | A simple method for displaying the hydropathic character of a protein. | J Kyte, R F Doolittle | J. Mol. Biol. | 1982 | 7108955 | Yes |
| 66 | 13761 | 6880.5 | 456.37 | 228.2 | Quantifying heterogeneity in a meta-analysis. | Julian P T Higgins, Simon G Thompson | Stat Med | 2002 | 12111919 | Yes |
| 67 | 7069 | 7069.0 | 261.68 | 261.7 | The pathogenesis of atherosclerosis: a perspective for the 1990s. | R Ross | Nature | 1993 | 8479518 | No |
| 68 | 6859 | 6859.0 | 248.11 | 248.1 | Vitamin D deficiency. | Michael F Holick | N. Engl. J. Med. | 2007 | 17634462 | No |
| 69 | 6757 | 6757.0 | 0.0 | 0.0 | Improvements in epoxy resin embedding methods. | J H LUFT | J Biophys Biochem Cytol | 1961 | 13764136 | Yes |
| 70 | 6554 | 6554.0 | 154.24 | 154.2 | The functions of animal microRNAs. | Victor Ambros | Nature | 2004 | 15372042 | No |
| 71 | 6540 | 6540.0 | 220.58 | 220.6 | Integrins: versatility, modulation, and signaling in cell adhesion. | R O Hynes | Cell | 1992 | 1555235 | No |
| 72 | 6422 | 6422.0 | 277.24 | 277.2 | Banting lecture 1988. Role of insulin resistance in human disease. | G M Reaven | Diabetes | 1988 | 3056758 | No |
| 73 | 6304 | 6304.0 | 0.0 | 0.0 | On the origin of cancer cells. | O WARBURG | Science | 1956 | 13298683 | Yes |
| 74 | 12693 | 6346.5 | 318.61 | 159.3 | Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. | Kazutoshi Takahashi, Shinya Yamanaka | Cell | 2006 | 16904174 | Yes |
| 75 | 6745 | 3372.5 | 151.67 | 75.8 | Processing of X-ray diffraction data collected in oscillation mode. | Z Otwinowski, W Minor | Meth. Enzymol. | 1997 | 27754618 | Yes |
| 76 | 6418 | 6418.0 | 370.3 | 370.3 | Psychophysical bases of perceived exertion. | G A Borg | Med Sci Sports Exerc | 1982 | 7154893 | Yes |
| 77 | 12872 | 6436.0 | 0.0 | 0.0 | The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. | K Weber, M Osborn | J. Biol. Chem. | 1969 | 5806584 | Yes |
| 78 | 24827 | 6206.8 | 882.0 | 220.5 | Measuring inconsistency in meta-analyses. | Julian P T Higgins, Simon G Thompson, Jonathan J Deeks, Douglas G Altman | BMJ | 2003 | 12958120 | No |
| 79 | 6200 | 6200.0 | 574.86 | 574.9 | Crystal structure refinement with SHELXL. | George M Sheldrick | Acta Crystallogr C Struct Chem | 2015 | 25567568 | Yes |
| 80 | 6182 | 6182.0 | 190.88 | 190.9 | Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. | M C Hochberg | Arthritis Rheum. | 1997 | 9324032 | Yes |
| 81 | 12393 | 6196.5 | 395.27 | 197.6 | Efficient iterative schemes for ab initio total-energy calculations using a plane-wave basis set. | Kresse, Furthmüller | Phys. Rev., B Condens. Matter | 1996 | 9984901 | Yes |
| 82 | 18231 | 6077.0 | 561.19 | 187.1 | Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. | Da Wei Huang, Brad T Sherman, Richard A Lempicki | Nat Protoc | 2009 | 19131956 | Yes |
| 83 | 12304 | 6152.0 | 345.94 | 173.0 | MrBayes 3: Bayesian phylogenetic inference under mixed models. | Fredrik Ronquist, John P Huelsenbeck | Bioinformatics | 2003 | 12912839 | Yes |
| 84 | 6124 | 6124.0 | 0.0 | 0.0 | COPPER ENZYMES IN ISOLATED CHLOROPLASTS. POLYPHENOLOXIDASE IN BETA VULGARIS. | D I Arnon | Plant Physiol. | 1949 | 16654194 | Yes |
| 85 | 17911 | 5970.3 | 523.21 | 174.4 | VMD: visual molecular dynamics. | W Humphrey, A Dalke, K Schulten | J Mol Graph | 1996 | 8744570 | Yes |
| 86 | 6131 | 6131.0 | 199.78 | 199.8 | TreeView: an application to display phylogenetic trees on personal computers. | R D Page | Comput. Appl. Biosci. | 1996 | 8902363 | Yes |
| 87 | 6071 | 6071.0 | 185.48 | 185.5 | Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. | F Tajima | Genetics | 1989 | 2513255 | Yes |
| 88 | 42495 | 6070.7 | 1261.85 | 180.3 | Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. | S F Altschul, T L Madden, A A Schäffer, J Zhang, Z Zhang, W Miller, D J Lipman | Nucleic Acids Res. | 1997 | 9254694 | No |
| 89 | 4207 | 4207.0 | 0.0 | 0.0 | Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. | A Böyum | Scand. J. Clin. Lab. Invest. Suppl. | 1968 | 4179068 | Yes |
| 90 | 5908 | 5908.0 | 200.41 | 200.4 | AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. | R W Cox | Comput. Biomed. Res. | 1996 | 8812068 | Yes |
| 91 | 23325 | 5831.2 | 1070.07 | 267.5 | A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. | M E Charlson, P Pompei, K L Ales, C R MacKenzie | J Chronic Dis | 1987 | 3558716 | Yes |
| 92 | 5912 | 5912.0 | 199.71 | 199.7 | Semiempirical GGA-type density functional constructed with a long-range dispersion correction. | Stefan Grimme | J Comput Chem | 2006 | 16955487 | Yes |
| 93 | 5798 | 5798.0 | 142.27 | 142.3 | Chromatin modifications and their function. | Tony Kouzarides | Cell | 2007 | 17320507 | No |
| 94 | 11591 | 5795.5 | 280.57 | 140.3 | Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana. | S J Clough, A F Bent | Plant J. | 1998 | 10069079 | Yes |
| 95 | 5812 | 5812.0 | 242.6 | 242.6 | Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. | P S Thomas | Proc. Natl. Acad. Sci. U.S.A. | 1980 | 6159641 | Yes |
| 96 | 5686 | 5686.0 | 159.66 | 159.7 | PAML 4: phylogenetic analysis by maximum likelihood. | Ziheng Yang | Mol. Biol. Evol. | 2007 | 17483113 | Yes |
| 97 | 5585 | 5585.0 | 221.95 | 221.9 | "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. | W N Burnette | Anal. Biochem. | 1981 | 6266278 | Yes |
| 98 | 22124 | 5531.0 | 860.49 | 215.1 | Bias in meta-analysis detected by a simple, graphical test. | M Egger, G Davey Smith, M Schneider, C Minder | BMJ | 1997 | 9310563 | Yes |
| 99 | 10910 | 5455.0 | 340.1 | 170.1 | Analyzing real-time PCR data by the comparative C(T) method. | Thomas D Schmittgen, Kenneth J Livak | Nat Protoc | 2008 | 18546601 | Yes |
| 100 | 5507 | 5507.0 | 0.0 | 0.0 | A simplification of the protein assay method of Lowry et al. which is more generally applicable. | G L Peterson | Anal. Biochem. | 1977 | 603028 | Yes |
| 101 | 5472 | 5472.0 | 160.23 | 160.2 | Fast robust automated brain extraction. | Stephen M Smith | Hum Brain Mapp | 2002 | 12391568 | No |
| 102 | 5429 | 5429.0 | 0.0 | 0.0 | Solvent content of protein crystals. | B W Matthews | J. Mol. Biol. | 1968 | 5700707 | Yes |
| 103 | 5421 | 5421.0 | 187.96 | 188.0 | The VideoToolbox software for visual psychophysics: transforming numbers into movies. | D G Pelli | Spat Vis | 1997 | 9176953 | Yes |
| 104 | 15216 | 5072.0 | 685.95 | 228.7 | NIH Image to ImageJ: 25 years of image analysis. | Caroline A Schneider, Wayne S Rasband, Kevin W Eliceiri | Nat. Methods | 2012 | 22930834 | No |
| 105 | 10693 | 5346.5 | 413.62 | 206.8 | Sequencing end-labeled DNA with base-specific chemical cleavages. | A M Maxam, W Gilbert | Meth. Enzymol. | 1980 | 6246368 | Yes |
| 106 | 5223 | 5223.0 | 218.9 | 218.9 | Ethical guidelines for investigations of experimental pain in conscious animals. | M Zimmermann | Pain | 1983 | 6877845 | No |
| 107 | 5008 | 5008.0 | 195.13 | 195.1 | The blockade of immune checkpoints in cancer immunotherapy. | Drew M Pardoll | Nat. Rev. Cancer | 2012 | 22437870 | No |
| 108 | 5141 | 5141.0 | 316.33 | 316.3 | Comparative fit indexes in structural models. | P M Bentler | Psychol Bull | 1990 | 2320703 | Yes |
| 109 | 5209 | 5209.0 | 0.0 | 0.0 | A low-viscosity epoxy resin embedding medium for electron microscopy. | A R Spurr | J. Ultrastruct. Res. | 1969 | 4887011 | Yes |
| 110 | 5057 | 5057.0 | 169.36 | 169.4 | Canonical dynamics: Equilibrium phase-space distributions. | Hoover | Phys Rev A Gen Phys | 1985 | 9895674 | Yes |
| 111 | 15488 | 5162.7 | 0.0 | 0.0 | Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. | W T Friedewald, R I Levy, D S Fredrickson | Clin. Chem. | 1972 | 4337382 | Yes |
| 112 | 15259 | 5086.3 | 577.37 | 192.5 | A new generation of Ca2+ indicators with greatly improved fluorescence properties. | G Grynkiewicz, M Poenie, R Y Tsien | J. Biol. Chem. | 1985 | 3838314 | Yes |
| 113 | 5062 | 5062.0 | 0.0 | 0.0 | Evaluation of survival data and two new rank order statistics arising in its consideration. | N Mantel | Cancer Chemother Rep | 1966 | 5910392 | Yes |
| 114 | 4967 | 4967.0 | 113.14 | 113.1 | Integrins: bidirectional, allosteric signaling machines. | Richard O Hynes | Cell | 2002 | 12297042 | No |
| 115 | 4723 | 4723.0 | 215.24 | 215.2 | Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. | Andreas Stang | Eur. J. Epidemiol. | 2010 | 20652370 | Yes |
| 116 | 4970 | 4970.0 | 203.91 | 203.9 | The role of protein kinase C in cell surface signal transduction and tumour promotion. | Y Nishizuka | Nature | 1984 | 6232463 | No |
| 117 | 18693 | 4673.2 | 929.91 | 232.5 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | PLoS Med. | 2009 | 19621072 | No |
| 118 | 9568 | 4784.0 | 220.39 | 110.2 | KEGG: kyoto encyclopedia of genes and genomes. | M Kanehisa, S Goto | Nucleic Acids Res. | 2000 | 10592173 | Yes |
| 119 | 4877 | 4877.0 | 0.0 | 0.0 | Tumor angiogenesis: therapeutic implications. | J Folkman | N. Engl. J. Med. | 1971 | 4938153 | No |
| 120 | 4873 | 4873.0 | 126.41 | 126.4 | Inflammation in atherosclerosis. | Peter Libby | Nature | 2002 | 12490960 | No |
| 121 | 9749 | 4874.5 | 0.0 | 0.0 | A rapid alkaline extraction procedure for screening recombinant plasmid DNA. | H C Birnboim, J Doly | Nucleic Acids Res. | 1979 | 388356 | Yes |
| 122 | 4881 | 4881.0 | 212.25 | 212.2 | Density-functional approximation for the correlation energy of the inhomogeneous electron gas. | Perdew | Phys. Rev., B Condens. Matter | 1986 | 9938299 | Yes |
| 123 | 4869 | 4869.0 | 152.78 | 152.8 | Angiogenesis in cancer, vascular, rheumatoid and other disease. | J Folkman | Nat. Med. | 1995 | 7584949 | No |
| 124 | 4799 | 4799.0 | 190.54 | 190.5 | The Clinical Dementia Rating (CDR): current version and scoring rules. | J C Morris | Neurology | 1993 | 8232972 | Yes |
| 125 | 4781 | 4781.0 | 134.69 | 134.7 | Inflammation, atherosclerosis, and coronary artery disease. | Göran K Hansson | N. Engl. J. Med. | 2005 | 15843671 | No |
| 126 | 4600 | 4600.0 | 143.45 | 143.4 | Apoptosis: a review of programmed cell death. | Susan Elmore | Toxicol Pathol | 2007 | 17562483 | No |
| 127 | 4781 | 4781.0 | 118.54 | 118.5 | p53, the cellular gatekeeper for growth and division. | A J Levine | Cell | 1997 | 9039259 | No |
| 128 | 4761 | 4761.0 | 0.0 | 0.0 | Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. | J R Vane | Nature New Biol. | 1971 | 5284360 | Yes |
| 129 | 4678 | 4678.0 | 131.99 | 132.0 | Biochemistry and molecular cell biology of diabetic complications. | M Brownlee | Nature | 2001 | 11742414 | Yes |
| 130 | 9420 | 4710.0 | 0.0 | 0.0 | Intraclass correlations: uses in assessing rater reliability. | P E Shrout, J L Fleiss | Psychol Bull | 1979 | 18839484 | No |
| 131 | 9349 | 4674.5 | 250.24 | 125.1 | A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. | Stéphane Guindon, Olivier Gascuel | Syst. Biol. | 2003 | 14530136 | Yes |
| 132 | 9297 | 4648.5 | 260.04 | 130.0 | MRBAYES: Bayesian inference of phylogenetic trees. | J P Huelsenbeck, F Ronquist | Bioinformatics | 2001 | 11524383 | Yes |
| 133 | 4656 | 4656.0 | 0.0 | 0.0 | Development of a rating scale for primary depressive illness. | M Hamilton | Br J Soc Clin Psychol | 1967 | 6080235 | Yes |
| 134 | 9354 | 4677.0 | 307.97 | 154.0 | MODELTEST: testing the model of DNA substitution. | D Posada, K A Crandall | Bioinformatics | 1998 | 9918953 | Yes |
| 135 | 4600 | 4600.0 | 94.13 | 94.1 | BLAT--the BLAST-like alignment tool. | W James Kent | Genome Res. | 2002 | 11932250 | Yes |
| 136 | 9277 | 4638.5 | 237.32 | 118.7 | Dendritic cells and the control of immunity. | J Banchereau, R M Steinman | Nature | 1998 | 9521319 | No |
| 137 | 8991 | 4495.5 | 0.0 | 0.0 | Continuous cultures of fused cells secreting antibody of predefined specificity. | G Köhler, C Milstein | Nature | 1975 | 1172191 | Yes |
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