No. | Citations | ECcit | RCR | ECRCR | Title | Authors | Journal | Year | PMID | Article(?) |
---|---|---|---|---|---|---|---|---|---|---|
1 | 224538 | 224538.0 | 5451.72 | 5451.7 | Cleavage of structural proteins during the assembly of the head of bacteriophage T4. | U K Laemmli | Nature | 1970 | 5432063 | Yes |
2 | 171981 | 171981.0 | 6760.41 | 6760.4 | A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. | M M Bradford | Anal Biochem | 1976 | 942051 | Yes |
3 | 285334 | 71333.5 | 0.0 | 0.0 | Protein measurement with the Folin phenol reagent. | O H Lowry, N J Rosebrough, A L Farr, R J Randall | J Biol Chem | 1951 | 14907713 | Yes |
4 | 119713 | 59856.5 | 2984.36 | 1492.2 | Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. | K J Livak, T D Schmittgen | Methods | 2001 | 11846609 | Yes |
5 | 45108 | 45108.0 | 1390.23 | 1390.2 | A short history of SHELX. | George M Sheldrick | Acta Crystallogr A | 2008 | 18156677 | Yes |
6 | 36559 | 36559.0 | 1177.3 | 1177.3 | Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. | T Mosmann | J Immunol Methods | 1983 | 6606682 | Yes |
7 | 64359 | 32179.5 | 1929.97 | 965.0 | Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. | P Chomczynski, N Sacchi | Anal Biochem | 1987 | 2440339 | Yes |
8 | 30258 | 30258.0 | 820.68 | 820.7 | Detection of specific sequences among DNA fragments separated by gel electrophoresis. | E M Southern | J Mol Biol | 1975 | 1195397 | Yes |
9 | 27703 | 27703.0 | 901.54 | 901.5 | The assessment and analysis of handedness: the Edinburgh inventory. | R C Oldfield | Neuropsychologia | 1971 | 5146491 | Yes |
10 | 27608 | 27608.0 | 609.26 | 609.3 | MicroRNAs: genomics, biogenesis, mechanism, and function. | David P Bartel | Cell | 2004 | 14744438 | No |
11 | 26302 | 26302.0 | 622.11 | 622.1 | MUSCLE: multiple sequence alignment with high accuracy and high throughput. | Robert C Edgar | Nucleic Acids Res | 2004 | 15034147 | Yes |
12 | 25747 | 25747.0 | 670.16 | 670.2 | A rating scale for depression. | M Hamilton | J Neurol Neurosurg Psychiatry | 1960 | 14399272 | Yes |
13 | 24344 | 24344.0 | 560.81 | 560.8 | A new mathematical model for relative quantification in real-time RT-PCR. | M W Pfaffl | Nucleic Acids Res | 2001 | 11328886 | Yes |
14 | 24279 | 24279.0 | 752.6 | 752.6 | Confidence Limits On Phylogenies: An Approach Using The Bootstrap. | Joseph Felsenstein | Evolution | 1985 | 28561359 | Yes |
15 | 65935 | 21978.3 | 1647.38 | 549.1 | DNA sequencing with chain-terminating inhibitors. | F Sanger, S Nicklen, A R Coulson | Proc Natl Acad Sci U S A | 1977 | 271968 | Yes |
16 | 65676 | 21892.0 | 2477.95 | 826.0 | "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. | M F Folstein, S E Folstein, P R McHugh | J Psychiatr Res | 1975 | 1202204 | Yes |
17 | 41711 | 20855.5 | 1311.64 | 655.8 | Hallmarks of cancer: the next generation. | Douglas Hanahan, Robert A Weinberg | Cell | 2011 | 21376230 | No |
18 | 20600 | 20600.0 | 710.61 | 710.6 | Density-functional exchange-energy approximation with correct asymptotic behavior. | A D Becke | Phys Rev A Gen Phys | 1988 | 9900728 | Yes |
19 | 20257 | 20257.0 | 147.11 | 147.1 | The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. | E S Reynolds | J Cell Biol | 1963 | 13986422 | Yes |
20 | 39594 | 19797.0 | 1220.64 | 610.3 | The neighbor-joining method: a new method for reconstructing phylogenetic trees. | N Saitou, M Nei | Mol Biol Evol | 1987 | 3447015 | Yes |
21 | 19432 | 19432.0 | 0.0 | 0.0 | Tissue sulfhydryl groups. | G L Ellman | Arch Biochem Biophys | 1959 | 13650640 | Yes |
22 | 35975 | 17987.5 | 1700.85 | 850.4 | Statistical methods for assessing agreement between two methods of clinical measurement. | J M Bland, D G Altman | Lancet | 1986 | 2868172 | Yes |
23 | 17886 | 17886.0 | 501.14 | 501.1 | Projector augmented-wave method. | P E Blöchl | Phys Rev B Condens Matter | 1994 | 9976227 | Yes |
24 | 53524 | 17841.3 | 1974.25 | 658.1 | Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. | H Towbin, T Staehelin, J Gordon | Proc Natl Acad Sci U S A | 1979 | 388439 | Yes |
25 | 34973 | 17486.5 | 1463.79 | 731.9 | The measurement of observer agreement for categorical data. | J R Landis, G G Koch | Biometrics | 1977 | 843571 | Yes |
26 | 17038 | 17038.0 | 623.79 | 623.8 | A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences. | M Kimura | J Mol Evol | 1980 | 7463489 | Yes |
27 | 16893 | 16893.0 | 424.4 | 424.4 | Atherosclerosis--an inflammatory disease. | R Ross | N Engl J Med | 1999 | 9887164 | No |
28 | 16795 | 16795.0 | 637.89 | 637.9 | Disc Electrophoresis. Ii. Method And Application To Human Serum Proteins. | B J Davis | Ann N Y Acad Sci | 1964 | 14240539 | Yes |
29 | 16366 | 16366.0 | 708.67 | 708.7 | RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies. | Alexandros Stamatakis | Bioinformatics | 2014 | 24451623 | Yes |
30 | 16193 | 16193.0 | 447.12 | 447.1 | High resolution two-dimensional electrophoresis of proteins. | P H O'Farrell | J Biol Chem | 1975 | 236308 | Yes |
31 | 32171 | 16085.5 | 0.0 | 0.0 | A rapid method of total lipid extraction and purification. | E G Bligh, W J Dyer | Can J Biochem Physiol | 1959 | 13671378 | Yes |
32 | 15941 | 15941.0 | 0.0 | 0.0 | A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. | K Burton | Biochem J | 1956 | 13293190 | Yes |
33 | 15919 | 15919.0 | 655.21 | 655.2 | A power primer. | J Cohen | Psychol Bull | 1992 | 19565683 | Yes |
34 | 15242 | 15242.0 | 385.25 | 385.2 | MicroRNAs: target recognition and regulatory functions. | David P Bartel | Cell | 2009 | 19167326 | No |
35 | 45196 | 15065.3 | 1289.82 | 429.9 | CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. | J D Thompson, D G Higgins, T J Gibson | Nucleic Acids Res | 1994 | 7984417 | Yes |
36 | 44928 | 14976.0 | 1333.65 | 444.6 | Generalized Gradient Approximation Made Simple. | J P Perdew, K Burke, M Ernzerhof | Phys Rev Lett | 1996 | 10062328 | Yes |
37 | 29627 | 14813.5 | 1186.43 | 593.2 | The hospital anxiety and depression scale. | A S Zigmond, R P Snaith | Acta Psychiatr Scand | 1983 | 6880820 | Yes |
38 | 29370 | 14685.0 | 1102.51 | 551.3 | Meta-analysis in clinical trials. | R DerSimonian, N Laird | Control Clin Trials | 1986 | 3802833 | Yes |
39 | 29110 | 14555.0 | 936.29 | 468.1 | Fast gapped-read alignment with Bowtie 2. | Ben Langmead, Steven L Salzberg | Nat Methods | 2012 | 22388286 | Yes |
40 | 28628 | 14314.0 | 728.07 | 364.0 | Fast and accurate short read alignment with Burrows-Wheeler transform. | Heng Li, Richard Durbin | Bioinformatics | 2009 | 19451168 | Yes |
41 | 14231 | 14231.0 | 554.36 | 554.4 | Catalase in vitro. | H Aebi | Methods Enzymol | 1984 | 6727660 | Yes |
42 | 41557 | 13852.3 | 0.0 | 0.0 | A simple method for the isolation and purification of total lipides from animal tissues. | J Folch, M Lees, G H Sloane Stanley | J Biol Chem | 1957 | 13428781 | Yes |
43 | 40894 | 13631.3 | 1539.81 | 513.3 | Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. | Michael I Love, Wolfgang Huber, Simon Anders | Genome Biol | 2014 | 25516281 | Yes |
44 | 12970 | 12970.0 | 682.27 | 682.3 | Crystal structure refinement with SHELXL. | George M Sheldrick | Acta Crystallogr C Struct Chem | 2015 | 25567568 | Yes |
45 | 12613 | 12613.0 | 0.0 | 0.0 | Phosphorus assay in column chromatography. | G R Bartlett | J Biol Chem | 1959 | 13641241 | Yes |
46 | 62320 | 12464.0 | 1784.19 | 356.8 | Basic local alignment search tool. | S F Altschul, W Gish, W Miller, E W Myers, D J Lipman | J Mol Biol | 1990 | 2231712 | Yes |
47 | 24550 | 12275.0 | 508.07 | 254.0 | Coot: model-building tools for molecular graphics. | Paul Emsley, Kevin Cowtan | Acta Crystallogr D Biol Crystallogr | 2004 | 15572765 | Yes |
48 | 36689 | 12229.7 | 1300.8 | 433.6 | Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density. | C Lee, W Yang, R G Parr | Phys Rev B Condens Matter | 1988 | 9944570 | Yes |
49 | 12218 | 12218.0 | 396.96 | 397.0 | Search and clustering orders of magnitude faster than BLAST. | Robert C Edgar | Bioinformatics | 2010 | 20709691 | Yes |
50 | 24398 | 12199.0 | 1001.72 | 500.9 | The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. | J E Ware, C D Sherbourne | Med Care | 1992 | 1593914 | Yes |
51 | 24088 | 12044.0 | 527.49 | 263.7 | Processing of X-ray diffraction data collected in oscillation mode. | Z Otwinowski, W Minor | Methods Enzymol | 1997 | 27754618 | Yes |
52 | 11950 | 11950.0 | 308.38 | 308.4 | Xds. | Wolfgang Kabsch | Acta Crystallogr D Biol Crystallogr | 2010 | 20124692 | Yes |
53 | 23752 | 11876.0 | 653.17 | 326.6 | Efficient iterative schemes for ab initio total-energy calculations using a plane-wave basis set. | G Kresse, J Furthmüller | Phys Rev B Condens Matter | 1996 | 9984901 | Yes |
54 | 11787 | 11787.0 | 134.32 | 134.3 | The genetics of Caenorhabditis elegans. | S Brenner | Genetics | 1974 | 4366476 | Yes |
55 | 11615 | 11615.0 | 381.99 | 382.0 | Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). | J F Kurtzke | Neurology | 1983 | 6685237 | Yes |
56 | 11612 | 11612.0 | 351.03 | 351.0 | The Psychophysics Toolbox. | D H Brainard | Spat Vis | 1997 | 9176952 | Yes |
57 | 23138 | 11569.0 | 626.26 | 313.1 | Quantifying heterogeneity in a meta-analysis. | Julian P T Higgins, Simon G Thompson | Stat Med | 2002 | 12111919 | Yes |
58 | 11537 | 11537.0 | 539.5 | 539.5 | Self-efficacy: toward a unifying theory of behavioral change. | A Bandura | Psychol Rev | 1977 | 847061 | Yes |
59 | 21584 | 10792.0 | 558.53 | 279.3 | A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. | A P Feinberg, B Vogelstein | Anal Biochem | 1983 | 6312838 | Yes |
60 | 10728 | 10728.0 | 410.23 | 410.2 | A new method for measuring daytime sleepiness: the Epworth sleepiness scale. | M W Johns | Sleep | 1991 | 1798888 | Yes |
61 | 21033 | 10516.5 | 460.8 | 230.4 | [20] Processing of X-ray diffraction data collected in oscillation mode. | Zbyszek Otwinowski, Wladek Minor | Methods Enzymol | 1997 | 27799103 | Yes |
62 | 10503 | 10503.0 | 365.36 | 365.4 | Structure validation in chemical crystallography. | Anthony L Spek | Acta Crystallogr D Biol Crystallogr | 2009 | 19171970 | Yes |
63 | 10450 | 10450.0 | 366.92 | 366.9 | Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. | Andreas Stang | Eur J Epidemiol | 2010 | 20652370 | Yes |
64 | 31301 | 10433.7 | 1246.29 | 415.4 | Trimmomatic: a flexible trimmer for Illumina sequence data. | Anthony M Bolger, Marc Lohse, Bjoern Usadel | Bioinformatics | 2014 | 24695404 | Yes |
65 | 10308 | 10308.0 | 202.5 | 202.5 | Improvements in epoxy resin embedding methods. | J H Luft | J Biophys Biochem Cytol | 1961 | 13764136 | Yes |
66 | 30752 | 10250.7 | 799.66 | 266.6 | VMD: visual molecular dynamics. | W Humphrey, A Dalke, K Schulten | J Mol Graph | 1996 | 8744570 | Yes |
67 | 10242 | 10242.0 | 417.43 | 417.4 | Investigation of the freely available easy-to-use software 'EZR' for medical statistics. | Y Kanda | Bone Marrow Transplant | 2013 | 23208313 | Yes |
68 | 20358 | 10179.0 | 878.66 | 439.3 | The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. | R M Baron, D A Kenny | J Pers Soc Psychol | 1986 | 3806354 | Yes |
69 | 40483 | 10120.8 | 1574.01 | 393.5 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | PLoS Med | 2009 | 19621072 | No |
70 | 40263 | 10065.8 | 1154.05 | 288.5 | Measuring inconsistency in meta-analyses. | Julian P T Higgins, Simon G Thompson, Jonathan J Deeks, Douglas G Altman | BMJ | 2003 | 12958120 | No |
71 | 19925 | 9962.5 | 775.35 | 387.7 | MAFFT multiple sequence alignment software version 7: improvements in performance and usability. | Kazutaka Katoh, Daron M Standley | Mol Biol Evol | 2013 | 23329690 | Yes |
72 | 29785 | 9928.3 | 1016.98 | 339.0 | NIH Image to ImageJ: 25 years of image analysis. | Caroline A Schneider, Wayne S Rasband, Kevin W Eliceiri | Nat Methods | 2012 | 22930834 | No |
73 | 19791 | 9895.5 | 402.1 | 201.1 | The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. | K Weber, M Osborn | J Biol Chem | 1969 | 5806584 | Yes |
74 | 9787 | 9787.0 | 0.0 | 0.0 | On the origin of cancer cells. | O Warburg | Science | 1956 | 13298683 | Yes |
75 | 9616 | 9616.0 | 322.91 | 322.9 | Banting lecture 1988. Role of insulin resistance in human disease. | G M Reaven | Diabetes | 1988 | 3056758 | No |
76 | 19181 | 9590.5 | 413.52 | 206.8 | KEGG: kyoto encyclopedia of genes and genomes. | M Kanehisa, S Goto | Nucleic Acids Res | 2000 | 10592173 | Yes |
77 | 9555 | 9555.0 | 268.54 | 268.5 | Evolutionary trees from DNA sequences: a maximum likelihood approach. | J Felsenstein | J Mol Evol | 1981 | 7288891 | Yes |
78 | 18911 | 9455.5 | 487.84 | 243.9 | A simple method for displaying the hydropathic character of a protein. | J Kyte, R F Doolittle | J Mol Biol | 1982 | 7108955 | Yes |
79 | 9444 | 9444.0 | 197.15 | 197.2 | Mfold web server for nucleic acid folding and hybridization prediction. | Michael Zuker | Nucleic Acids Res | 2003 | 12824337 | Yes |
80 | 9365 | 9365.0 | 250.61 | 250.6 | Semiempirical GGA-type density functional constructed with a long-range dispersion correction. | Stefan Grimme | J Comput Chem | 2006 | 16955487 | Yes |
81 | 9350 | 9350.0 | 247.33 | 247.3 | Studies on transformation of Escherichia coli with plasmids. | D Hanahan | J Mol Biol | 1983 | 6345791 | Yes |
82 | 9277 | 9277.0 | 399.78 | 399.8 | Psychophysical bases of perceived exertion. | G A Borg | Med Sci Sports Exerc | 1982 | 7154893 | Yes |
83 | 9262 | 9262.0 | 262.77 | 262.8 | Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. | P S Thomas | Proc Natl Acad Sci U S A | 1980 | 6159641 | Yes |
84 | 9213 | 9213.0 | 267.33 | 267.3 | Vitamin D deficiency. | Michael F Holick | N Engl J Med | 2007 | 17634462 | No |
85 | 9204 | 9204.0 | 239.42 | 239.4 | RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. | Alexandros Stamatakis | Bioinformatics | 2006 | 16928733 | Yes |
86 | 9179 | 9179.0 | 259.39 | 259.4 | The pathogenesis of atherosclerosis: a perspective for the 1990s. | R Ross | Nature | 1993 | 8479518 | No |
87 | 9071 | 9071.0 | 234.12 | 234.1 | Integrins: versatility, modulation, and signaling in cell adhesion. | R O Hynes | Cell | 1992 | 1555235 | No |
88 | 18141 | 9070.5 | 381.47 | 190.7 | The hallmarks of cancer. | D Hanahan, R A Weinberg | Cell | 2000 | 10647931 | No |
89 | 9038 | 9038.0 | 268.02 | 268.0 | The blockade of immune checkpoints in cancer immunotherapy. | Drew M Pardoll | Nat Rev Cancer | 2012 | 22437870 | No |
90 | 35782 | 8945.5 | 1313.86 | 328.5 | A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. | M E Charlson, P Pompei, K L Ales, C R MacKenzie | J Chronic Dis | 1987 | 3558716 | Yes |
91 | 8914 | 8914.0 | 411.55 | 411.6 | Prokka: rapid prokaryotic genome annotation. | Torsten Seemann | Bioinformatics | 2014 | 24642063 | Yes |
92 | 8801 | 8801.0 | 178.4 | 178.4 | Linear models and empirical bayes methods for assessing differential expression in microarray experiments. | Gordon K Smyth | Stat Appl Genet Mol Biol | 2004 | 16646809 | Yes |
93 | 26137 | 8712.3 | 674.08 | 224.7 | Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. | Da Wei Huang, Brad T Sherman, Richard A Lempicki | Nat Protoc | 2009 | 19131956 | Yes |
94 | 34327 | 8581.8 | 1108.68 | 277.2 | Bias in meta-analysis detected by a simple, graphical test. | M Egger, G Davey Smith, M Schneider, C Minder | BMJ | 1997 | 9310563 | Yes |
95 | 8576 | 8576.0 | 222.85 | 222.8 | Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. | M C Hochberg | Arthritis Rheum | 1997 | 9324032 | Yes |
96 | 17125 | 8562.5 | 452.54 | 226.3 | Analyzing real-time PCR data by the comparative C(T) method. | Thomas D Schmittgen, Kenneth J Livak | Nat Protoc | 2008 | 18546601 | Yes |
97 | 8514 | 8514.0 | 0.0 | 0.0 | Copper Enzymes In Isolated Chloroplasts. Polyphenoloxidase In Beta Vulgaris. | D I Arnon | Plant Physiol | 1949 | 16654194 | Yes |
98 | 16963 | 8481.5 | 373.75 | 186.9 | Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. | Kazutoshi Takahashi, Shinya Yamanaka | Cell | 2006 | 16904174 | Yes |
99 | 8480 | 8480.0 | 179.98 | 180.0 | The functions of animal microRNAs. | Victor Ambros | Nature | 2004 | 15372042 | No |
100 | 8440 | 8440.0 | 204.54 | 204.5 | PAML 4: phylogenetic analysis by maximum likelihood. | Ziheng Yang | Mol Biol Evol | 2007 | 17483113 | Yes |
101 | 50591 | 8431.8 | 3506.43 | 584.4 | Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. | Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal | CA Cancer J Clin | 2018 | 30207593 | Yes |
102 | 8359 | 8359.0 | 219.4 | 219.4 | Canonical dynamics: Equilibrium phase-space distributions. | W G Hoover | Phys Rev A Gen Phys | 1985 | 9895674 | Yes |
103 | 8119 | 8119.0 | 0.0 | 0.0 | The assessment of anxiety states by rating. | M Hamilton | Br J Med Psychol | 1959 | 13638508 | Yes |
104 | 8084 | 8084.0 | 172.74 | 172.7 | Solvent content of protein crystals. | B W Matthews | J Mol Biol | 1968 | 5700707 | Yes |
105 | 8011 | 8011.0 | 210.51 | 210.5 | Apoptosis: a review of programmed cell death. | Susan Elmore | Toxicol Pathol | 2007 | 17562483 | No |
106 | 8000 | 8000.0 | 344.93 | 344.9 | UPARSE: highly accurate OTU sequences from microbial amplicon reads. | Robert C Edgar | Nat Methods | 2013 | 23955772 | Yes |
107 | 23982 | 7994.0 | 1376.29 | 458.8 | MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets. | Sudhir Kumar, Glen Stecher, Koichiro Tamura | Mol Biol Evol | 2016 | 27004904 | Yes |
108 | 7979 | 7979.0 | 235.06 | 235.1 | AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. | R W Cox | Comput Biomed Res | 1996 | 8812068 | Yes |
109 | 7931 | 7931.0 | 406.22 | 406.2 | SHELXT - integrated space-group and crystal-structure determination. | George M Sheldrick | Acta Crystallogr A Found Adv | 2015 | 25537383 | Yes |
110 | 7864 | 7864.0 | 217.47 | 217.5 | "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. | W N Burnette | Anal Biochem | 1981 | 6266278 | Yes |
111 | 23454 | 7818.0 | 629.04 | 209.7 | edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. | Mark D Robinson, Davis J McCarthy, Gordon K Smyth | Bioinformatics | 2010 | 19910308 | Yes |
112 | 7811 | 7811.0 | 216.41 | 216.4 | The role of protein kinase C in cell surface signal transduction and tumour promotion. | Y Nishizuka | Nature | 1984 | 6232463 | No |
113 | 7790 | 7790.0 | 225.21 | 225.2 | A simplification of the protein assay method of Lowry et al. which is more generally applicable. | G L Peterson | Anal Biochem | 1977 | 603028 | Yes |
114 | 7762 | 7762.0 | 359.24 | 359.2 | Comparative fit indexes in structural models. | P M Bentler | Psychol Bull | 1990 | 2320703 | Yes |
115 | 15482 | 7741.0 | 378.41 | 189.2 | MrBayes 3: Bayesian phylogenetic inference under mixed models. | Fredrik Ronquist, John P Huelsenbeck | Bioinformatics | 2003 | 12912839 | Yes |
116 | 7673 | 7673.0 | 206.24 | 206.2 | Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. | F Tajima | Genetics | 1989 | 2513255 | Yes |
117 | 7654 | 7654.0 | 156.45 | 156.4 | Tumor angiogenesis: therapeutic implications. | J Folkman | N Engl J Med | 1971 | 4938153 | No |
118 | 7641 | 7641.0 | 226.66 | 226.7 | Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. | J R Vane | Nat New Biol | 1971 | 5284360 | Yes |
119 | 7581 | 7581.0 | 199.93 | 199.9 | Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. | A Böyum | Scand J Clin Lab Invest Suppl | 1968 | 4179068 | Yes |
120 | 15123 | 7561.5 | 338.84 | 169.4 | Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana. | S J Clough, A F Bent | Plant J | 1998 | 10069079 | Yes |
121 | 7561 | 7561.0 | 251.2 | 251.2 | Density-functional approximation for the correlation energy of the inhomogeneous electron gas. | J P Perdew | Phys Rev B Condens Matter | 1986 | 9938299 | Yes |
122 | 22518 | 7506.0 | 666.2 | 222.1 | The PHQ-9: validity of a brief depression severity measure. | K Kroenke, R L Spitzer, J B Williams | J Gen Intern Med | 2001 | 11556941 | Yes |
123 | 7470 | 7470.0 | 160.06 | 160.1 | Chromatin modifications and their function. | Tony Kouzarides | Cell | 2007 | 17320507 | No |
124 | 7436 | 7436.0 | 184.03 | 184.0 | Fast robust automated brain extraction. | Stephen M Smith | Hum Brain Mapp | 2002 | 12391568 | No |
125 | 22226 | 7408.7 | 840.06 | 280.0 | Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. | W T Friedewald, R I Levy, D S Fredrickson | Clin Chem | 1972 | 4337382 | Yes |
126 | 7357 | 7357.0 | 134.42 | 134.4 | A low-viscosity epoxy resin embedding medium for electron microscopy. | A R Spurr | J Ultrastruct Res | 1969 | 4887011 | Yes |
127 | 51206 | 7315.1 | 1319.24 | 188.5 | Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. | S F Altschul, T L Madden, A A Schäffer, J Zhang, Z Zhang, W Miller, D J Lipman | Nucleic Acids Res | 1997 | 9254694 | No |
128 | 14389 | 7194.5 | 484.24 | 242.1 | Three approaches to qualitative content analysis. | Hsiu-Fang Hsieh, Sarah E Shannon | Qual Health Res | 2005 | 16204405 | Yes |
129 | 21439 | 7146.3 | 651.53 | 217.2 | Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. | Daniel Dindo, Nicolas Demartines, Pierre-Alain Clavien | Ann Surg | 2004 | 15273542 | Yes |
130 | 7066 | 7066.0 | 213.59 | 213.6 | The VideoToolbox software for visual psychophysics: transforming numbers into movies. | D G Pelli | Spat Vis | 1997 | 9176953 | Yes |
131 | 7044 | 7044.0 | 223.28 | 223.3 | The Clinical Dementia Rating (CDR): current version and scoring rules. | J C Morris | Neurology | 1993 | 8232972 | Yes |
132 | 7041 | 7041.0 | 191.21 | 191.2 | TreeView: an application to display phylogenetic trees on personal computers. | R D Page | Comput Appl Biosci | 1996 | 8902363 | Yes |
133 | 13966 | 6983.0 | 435.08 | 217.5 | AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. | Oleg Trott, Arthur J Olson | J Comput Chem | 2010 | 19499576 | Yes |
134 | 13937 | 6968.5 | 334.4 | 167.2 | BEDTools: a flexible suite of utilities for comparing genomic features. | Aaron R Quinlan, Ira M Hall | Bioinformatics | 2010 | 20110278 | Yes |
135 | 13816 | 6908.0 | 353.57 | 176.8 | Continuous cultures of fused cells secreting antibody of predefined specificity. | G Köhler, C Milstein | Nature | 1975 | 1172191 | Yes |
136 | 6858 | 6858.0 | 184.51 | 184.5 | The steroid and thyroid hormone receptor superfamily. | R M Evans | Science | 1988 | 3283939 | No |
137 | 6775 | 6775.0 | 238.04 | 238.0 | The Strengths and Difficulties Questionnaire: a research note. | R Goodman | J Child Psychol Psychiatry | 1997 | 9255702 | Yes |
138 | 27022 | 6755.5 | 888.6 | 222.2 | G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. | Franz Faul, Edgar Erdfelder, Albert-Georg Lang, Axel Buchner | Behav Res Methods | 2007 | 17695343 | Yes |
139 | 6696 | 6696.0 | 0.0 | 0.0 | The thiobarbituric acid assay of sialic acids. | L Warren | J Biol Chem | 1959 | 13672998 | Yes |
140 | 6577 | 6577.0 | 172.49 | 172.5 | Adhesion receptors of the immune system. | T A Springer | Nature | 1990 | 1974032 | No |
141 | 13119 | 6559.5 | 309.38 | 154.7 | Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. | Y Cheng, W H Prusoff | Biochem Pharmacol | 1973 | 4202581 | Yes |
142 | 19622 | 6540.7 | 549.3 | 183.1 | A new generation of Ca2+ indicators with greatly improved fluorescence properties. | G Grynkiewicz, M Poenie, R Y Tsien | J Biol Chem | 1985 | 3838314 | Yes |
143 | 6536 | 6536.0 | 213.25 | 213.2 | Ethical guidelines for investigations of experimental pain in conscious animals. | Manfred Zimmermann | Pain | 1983 | 6877845 | No |
144 | 6516 | 6516.0 | 168.97 | 169.0 | Angiogenesis in cancer, vascular, rheumatoid and other disease. | J Folkman | Nat Med | 1995 | 7584949 | No |
145 | 12967 | 6483.5 | 701.18 | 350.6 | Intraclass correlations: uses in assessing rater reliability. | P E Shrout, J L Fleiss | Psychol Bull | 1979 | 18839484 | No |
146 | 12930 | 6465.0 | 0.0 | 0.0 | Statistical aspects of the analysis of data from retrospective studies of disease. | N Mantel, W Haenszel | J Natl Cancer Inst | 1959 | 13655060 | Yes |
147 | 6463 | 6463.0 | 128.51 | 128.5 | Integrins: bidirectional, allosteric signaling machines. | Richard O Hynes | Cell | 2002 | 12297042 | No |
148 | 6396 | 6396.0 | 128.72 | 128.7 | Rapid and efficient site-specific mutagenesis without phenotypic selection. | T A Kunkel | Proc Natl Acad Sci U S A | 1985 | 3881765 | Yes |
149 | 6374 | 6374.0 | 168.99 | 169.0 | A modified poisson regression approach to prospective studies with binary data. | Guangyong Zou | Am J Epidemiol | 2004 | 15033648 | Yes |
150 | 6341 | 6341.0 | 135.6 | 135.6 | p53, the cellular gatekeeper for growth and division. | A J Levine | Cell | 1997 | 9039259 | No |
151 | 6312 | 6312.0 | 149.17 | 149.2 | Inflammation, atherosclerosis, and coronary artery disease. | Göran K Hansson | N Engl J Med | 2005 | 15843671 | No |
152 | 12553 | 6276.5 | 348.03 | 174.0 | EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis. | Arnaud Delorme, Scott Makeig | J Neurosci Methods | 2004 | 15102499 | Yes |
153 | 12519 | 6259.5 | 500.71 | 250.4 | Prediction of creatinine clearance from serum creatinine. | D W Cockcroft, M H Gault | Nephron | 1976 | 1244564 | Yes |
154 | 6249 | 6249.0 | 111.68 | 111.7 | A Self-Rating Depression Scale. | W W Zung | Arch Gen Psychiatry | 1965 | 14221692 | Yes |
155 | 12450 | 6225.0 | 426.85 | 213.4 | The meaning and use of the area under a receiver operating characteristic (ROC) curve. | J A Hanley, B J McNeil | Radiology | 1982 | 7063747 | Yes |
156 | 6183 | 6183.0 | 135.29 | 135.3 | Inflammation in atherosclerosis. | Peter Libby | Nature | 2002 | 12490960 | No |
157 | 6147 | 6147.0 | 143.99 | 144.0 | Free radicals in the physiological control of cell function. | Wulf Dröge | Physiol Rev | 2002 | 11773609 | No |
158 | 6144 | 6144.0 | 145.72 | 145.7 | Biochemistry and molecular cell biology of diabetic complications. | M Brownlee | Nature | 2001 | 11742414 | Yes |
159 | 12250 | 6125.0 | 431.03 | 215.5 | A rapid alkaline extraction procedure for screening recombinant plasmid DNA. | H C Birnboim, J Doly | Nucleic Acids Res | 1979 | 388356 | Yes |
160 | 6119 | 6119.0 | 149.72 | 149.7 | Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. | T A Springer | Cell | 1994 | 7507411 | No |
161 | 6096 | 6096.0 | 0.0 | 0.0 | Index for rating diagnostic tests. | W J Youden | Cancer | 1950 | 15405679 | Yes |
162 | 6048 | 6048.0 | 139.12 | 139.1 | Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis. | J Castresana | Mol Biol Evol | 2000 | 10742046 | Yes |
163 | 18131 | 6043.7 | 894.63 | 298.2 | Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. | H Ohkawa, N Ohishi, K Yagi | Anal Biochem | 1979 | 36810 | Yes |
164 | 6040 | 6040.0 | 152.32 | 152.3 | Inositol trisphosphate and calcium signalling. | M J Berridge | Nature | 1993 | 8381210 | No |
165 | 6028 | 6028.0 | 152.83 | 152.8 | G proteins: transducers of receptor-generated signals. | A G Gilman | Annu Rev Biochem | 1987 | 3113327 | No |
166 | 12044 | 6022.0 | 284.51 | 142.3 | WGCNA: an R package for weighted correlation network analysis. | Peter Langfelder, Steve Horvath | BMC Bioinformatics | 2008 | 19114008 | Yes |
167 | 6020 | 6020.0 | 113.17 | 113.2 | BLAT--the BLAST-like alignment tool. | W James Kent | Genome Res | 2002 | 11932250 | Yes |
168 | 6003 | 6003.0 | 209.63 | 209.6 | An Introduction to Propensity Score Methods for Reducing the Effects of Confounding in Observational Studies. | Peter C Austin | Multivariate Behav Res | 2011 | 21818162 | Yes |
169 | 24002 | 6000.5 | 767.09 | 191.8 | Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. | J M Chirgwin, A E Przybyla, R J MacDonald, W J Rutter | Biochemistry | 1979 | 518835 | Yes |
170 | 5901 | 5901.0 | 143.13 | 143.1 | Inflammation and metabolic disorders. | Gökhan S Hotamisligil | Nature | 2006 | 17167474 | No |
171 | 11797 | 5898.5 | 287.68 | 143.8 | MRBAYES: Bayesian inference of phylogenetic trees. | J P Huelsenbeck, F Ronquist | Bioinformatics | 2001 | 11524383 | Yes |
172 | 5859 | 5859.0 | 135.58 | 135.6 | Antimicrobial peptides of multicellular organisms. | Michael Zasloff | Nature | 2002 | 11807545 | Yes |
173 | 11670 | 5835.0 | 328.65 | 164.3 | RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. | Bo Li, Colin N Dewey | BMC Bioinformatics | 2011 | 21816040 | Yes |
174 | 11501 | 5750.5 | 265.13 | 132.6 | Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features. | W Kabsch, C Sander | Biopolymers | 1983 | 6667333 | Yes |
175 | 5742 | 5742.0 | 171.4 | 171.4 | Modification of seizure activity by electrical stimulation. II. Motor seizure. | R J Racine | Electroencephalogr Clin Neurophysiol | 1972 | 4110397 | Yes |
176 | 40125 | 5732.1 | 6912.5 | 987.5 | Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. | Hyuna Sung, Jacques Ferlay, Rebecca L Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, Freddie Bray | CA Cancer J Clin | 2021 | 33538338 | Yes |
177 | 5725 | 5725.0 | 143.06 | 143.1 | Apoptosis in the pathogenesis and treatment of disease. | C B Thompson | Science | 1995 | 7878464 | No |
178 | 11400 | 5700.0 | 251.85 | 125.9 | Dendritic cells and the control of immunity. | J Banchereau, R M Steinman | Nature | 1998 | 9521319 | No |
179 | 11380 | 5690.0 | 435.21 | 217.6 | The Carbon Monoxide-Binding Pigment Of Liver Microsomes. I. Evidence For Its Hemoprotein Nature. | T Omura, R Sato | J Biol Chem | 1964 | 14209971 | Yes |
180 | 11362 | 5681.0 | 248.77 | 124.4 | One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. | K A Datsenko, B L Wanner | Proc Natl Acad Sci U S A | 2000 | 10829079 | Yes |
181 | 11323 | 5661.5 | 309.13 | 154.6 | Neuropathological stageing of Alzheimer-related changes. | H Braak, E Braak | Acta Neuropathol | 1991 | 1759558 | No |
182 | 5660 | 5660.0 | 74.27 | 74.3 | The Environment And Disease: Association Or Causation? | A B Hill | Proc R Soc Med | 1965 | 14283879 | Yes |
183 | 11205 | 5602.5 | 0.0 | 0.0 | A series of normal stages in the development of the chick embryo. | V Hamburger, H L Hamilton | J Morphol | 1951 | 24539719 | Yes |
184 | 5563 | 5563.0 | 176.54 | 176.5 | jModelTest: phylogenetic model averaging. | David Posada | Mol Biol Evol | 2008 | 18397919 | Yes |
185 | 5559 | 5559.0 | 0.0 | 0.0 | Aging: a theory based on free radical and radiation chemistry. | D Harman | J Gerontol | 1956 | 13332224 | Yes |
186 | 5548 | 5548.0 | 100.5 | 100.5 | Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. | F Tietze | Anal Biochem | 1969 | 4388022 | Yes |
187 | 5530 | 5530.0 | 133.37 | 133.4 | Development of a rating scale for primary depressive illness. | M Hamilton | Br J Soc Clin Psychol | 1967 | 6080235 | Yes |
188 | 5523 | 5523.0 | 154.99 | 155.0 | A fast diffeomorphic image registration algorithm. | John Ashburner | Neuroimage | 2007 | 17761438 | Yes |
189 | 11045 | 5522.5 | 289.86 | 144.9 | Sequencing end-labeled DNA with base-specific chemical cleavages. | A M Maxam, W Gilbert | Methods Enzymol | 1980 | 6246368 | Yes |
190 | 5511 | 5511.0 | 119.88 | 119.9 | The biochemistry of apoptosis. | M O Hengartner | Nature | 2000 | 11048727 | No |
191 | 5503 | 5503.0 | 122.21 | 122.2 | MUSCLE: a multiple sequence alignment method with reduced time and space complexity. | Robert C Edgar | BMC Bioinformatics | 2004 | 15318951 | Yes |
192 | 5484 | 5484.0 | 105.86 | 105.9 | Evaluation of survival data and two new rank order statistics arising in its consideration. | N Mantel | Cancer Chemother Rep | 1966 | 5910392 | Yes |
193 | 5476 | 5476.0 | 216.77 | 216.8 | Orienting of attention. | M I Posner | Q J Exp Psychol | 1980 | 7367577 | Yes |
194 | 10933 | 5466.5 | 254.75 | 127.4 | A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. | Stéphane Guindon, Olivier Gascuel | Syst Biol | 2003 | 14530136 | Yes |
195 | 5461 | 5461.0 | 95.58 | 95.6 | Mutation and cancer: statistical study of retinoblastoma. | A G Knudson | Proc Natl Acad Sci U S A | 1971 | 5279523 | Yes |
196 | 16353 | 5451.0 | 491.75 | 163.9 | A simple salting out procedure for extracting DNA from human nucleated cells. | S A Miller, D D Dykes, H F Polesky | Nucleic Acids Res | 1988 | 3344216 | Yes |
197 | 10839 | 5419.5 | 287.4 | 143.7 | Balanced basis sets of split valence, triple zeta valence and quadruple zeta valence quality for H to Rn: Design and assessment of accuracy. | Florian Weigend, Reinhart Ahlrichs | Phys Chem Chem Phys | 2005 | 16240044 | Yes |
198 | 10772 | 5386.0 | 755.36 | 377.7 | A Guideline of Selecting and Reporting Intraclass Correlation Coefficients for Reliability Research. | Terry K Koo, Mae Y Li | J Chiropr Med | 2016 | 27330520 | Yes |
199 | 5361 | 5361.0 | 138.52 | 138.5 | The Cambridge Structural Database: a quarter of a million crystal structures and rising. | Frank H Allen | Acta Crystallogr B | 2002 | 12037359 | Yes |
200 | 10702 | 5351.0 | 298.98 | 149.5 | MODELTEST: testing the model of DNA substitution. | D Posada, K A Crandall | Bioinformatics | 1998 | 9918953 | Yes |
201 | 10699 | 5349.5 | 227.56 | 113.8 | Inflammation and cancer. | Lisa M Coussens, Zena Werb | Nature | 2002 | 12490959 | No |
202 | 5313 | 5313.0 | 135.11 | 135.1 | New M13 vectors for cloning. | J Messing | Methods Enzymol | 1983 | 6310323 | Yes |
203 | 15901 | 5300.3 | 564.4 | 188.1 | Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. | Allison Tong, Peter Sainsbury, Jonathan Craig | Int J Qual Health Care | 2007 | 17872937 | Yes |
204 | 10586 | 5293.0 | 1030.7 | 515.4 | Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. | Zunyou Wu, Jennifer M McGoogan | JAMA | 2020 | 32091533 | Yes |
205 | 5288 | 5288.0 | 127.68 | 127.7 | The NF-kappa B and I kappa B proteins: new discoveries and insights. | A S Baldwin | Annu Rev Immunol | 1996 | 8717528 | No |
206 | 5286 | 5286.0 | 156.45 | 156.4 | Developments of a water-maze procedure for studying spatial learning in the rat. | R Morris | J Neurosci Methods | 1984 | 6471907 | Yes |
207 | 26405 | 5281.0 | 712.34 | 142.5 | The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. | J D Thompson, T J Gibson, F Plewniak, F Jeanmougin, D G Higgins | Nucleic Acids Res | 1997 | 9396791 | Yes |
208 | 5279 | 5279.0 | 152.55 | 152.6 | Studies and perspectives of protein kinase C. | Y Nishizuka | Science | 1986 | 3014651 | No |
209 | 10516 | 5258.0 | 271.75 | 135.9 | Differential expression analysis for sequence count data. | Simon Anders, Wolfgang Huber | Genome Biol | 2010 | 20979621 | Yes |
210 | 5241 | 5241.0 | 173.86 | 173.9 | Whatever happened to qualitative description? | M Sandelowski | Res Nurs Health | 2000 | 10940958 | No |
211 | 5241 | 5241.0 | 102.45 | 102.5 | Epithelial-mesenchymal transitions in tumour progression. | Jean Paul Thiery | Nat Rev Cancer | 2002 | 12189386 | No |
212 | 10477 | 5238.5 | 346.97 | 173.5 | Operating characteristics of a rank correlation test for publication bias. | C B Begg, M Mazumdar | Biometrics | 1994 | 7786990 | Yes |
213 | 5221 | 5221.0 | 0.0 | 0.0 | [A micro-method of immuno-electrophoresis]. | J J Scheidegger | Int Arch Allergy Appl Immunol | 1955 | 13262900 | Yes |
214 | 10435 | 5217.5 | 0.0 | 0.0 | A quantitative description of membrane current and its application to conduction and excitation in nerve. | A L Hodgkin, A F Huxley | J Physiol | 1952 | 12991237 | Yes |
215 | 5212 | 5212.0 | 189.11 | 189.1 | Oxygen-derived free radicals in postischemic tissue injury. | J M McCord | N Engl J Med | 1985 | 2981404 | No |
216 | 5191 | 5191.0 | 66.11 | 66.1 | Selective extraction of polyoma DNA from infected mouse cell cultures. | B Hirt | J Mol Biol | 1967 | 4291934 | Yes |
217 | 15561 | 5187.0 | 584.65 | 194.9 | The positive and negative syndrome scale (PANSS) for schizophrenia. | S R Kay, A Fiszbein, L A Opler | Schizophr Bull | 1987 | 3616518 | Yes |
218 | 10372 | 5186.0 | 483.41 | 241.7 | A new depression scale designed to be sensitive to change. | S A Montgomery, M Asberg | Br J Psychiatry | 1979 | 444788 | Yes |
219 | 5167 | 5167.0 | 136.67 | 136.7 | Mild cognitive impairment as a diagnostic entity. | R C Petersen | J Intern Med | 2004 | 15324362 | No |
220 | 10304 | 5152.0 | 365.23 | 182.6 | The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. | R F Furchgott, J V Zawadzki | Nature | 1980 | 6253831 | Yes |
221 | 5147 | 5147.0 | 52.87 | 52.9 | The Two Histological Main Types Of Gastric Carcinoma: Diffuse And So-Called Intestinal-Type Carcinoma. An Attempt At A Histo-Clinical Classification. | P Lauren | Acta Pathol Microbiol Scand | 1965 | 14320675 | Yes |
222 | 5118 | 5118.0 | 187.46 | 187.5 | Analyzing Tables Of Statistical Tests. | William R Rice | Evolution | 1989 | 28568501 | Yes |
223 | 5112 | 5112.0 | 232.3 | 232.3 | Interrater reliability: the kappa statistic. | Mary L McHugh | Biochem Med (Zagreb) | 2012 | 23092060 | Yes |
224 | 5111 | 5111.0 | 157.37 | 157.4 | Prejudice, social stress, and mental health in lesbian, gay, and bisexual populations: conceptual issues and research evidence. | Ilan H Meyer | Psychol Bull | 2003 | 12956539 | No |
225 | 10211 | 5105.5 | 271.1 | 135.6 | Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. | H Schägger, G von Jagow | Anal Biochem | 1987 | 2449095 | Yes |
226 | 5101 | 5101.0 | 101.72 | 101.7 | Rho GTPases and the actin cytoskeleton. | A Hall | Science | 1998 | 9438836 | No |
227 | 5091 | 5091.0 | 140.0 | 140.0 | How mitochondria produce reactive oxygen species. | Michael P Murphy | Biochem J | 2009 | 19061483 | No |
228 | 15253 | 5084.3 | 376.37 | 125.5 | Inference of population structure using multilocus genotype data. | J K Pritchard, M Stephens, P Donnelly | Genetics | 2000 | 10835412 | Yes |
229 | 5080 | 5080.0 | 124.12 | 124.1 | Emotion circuits in the brain. | J E LeDoux | Annu Rev Neurosci | 2000 | 10845062 | No |
230 | 5061 | 5061.0 | 192.89 | 192.9 | Revisiting the behavioral model and access to medical care: does it matter? | R M Andersen | J Health Soc Behav | 1995 | 7738325 | Yes |
231 | 10114 | 5057.0 | 240.68 | 120.3 | Comparative protein modelling by satisfaction of spatial restraints. | A Sali, T L Blundell | J Mol Biol | 1993 | 8254673 | Yes |
232 | 10057 | 5028.5 | 218.81 | 109.4 | The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. | John Hardy, Dennis J Selkoe | Science | 2002 | 12130773 | No |
233 | 5014 | 5014.0 | 101.33 | 101.3 | Targeting HIF-1 for cancer therapy. | Gregg L Semenza | Nat Rev Cancer | 2003 | 13130303 | No |
234 | 10021 | 5010.5 | 220.87 | 110.4 | MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. | Jürgen Cox, Matthias Mann | Nat Biotechnol | 2008 | 19029910 | Yes |
235 | 14943 | 4981.0 | 538.26 | 179.4 | Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. | S M Hsu, L Raine, H Fanger | J Histochem Cytochem | 1981 | 6166661 | Yes |
236 | 4959 | 4959.0 | 143.72 | 143.7 | A protein binding assay for adenosine 3':5'-cyclic monophosphate. | A G Gilman | Proc Natl Acad Sci U S A | 1970 | 4318781 | Yes |
237 | 4935 | 4935.0 | 111.67 | 111.7 | Tandem repeats finder: a program to analyze DNA sequences. | G Benson | Nucleic Acids Res | 1999 | 9862982 | Yes |
238 | 4922 | 4922.0 | 140.67 | 140.7 | Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies. | C B Laurell | Anal Biochem | 1966 | 5959431 | Yes |
239 | 24606 | 4921.2 | 1087.58 | 217.5 | MEGA6: Molecular Evolutionary Genetics Analysis version 6.0. | Koichiro Tamura, Glen Stecher, Daniel Peterson, Alan Filipski, Sudhir Kumar | Mol Biol Evol | 2013 | 24132122 | Yes |
240 | 4904 | 4904.0 | 191.98 | 192.0 | The need for a new medical model: a challenge for biomedicine. | G L Engel | Science | 1977 | 847460 | Yes |
241 | 9806 | 4903.0 | 350.09 | 175.0 | Ligand: a versatile computerized approach for characterization of ligand-binding systems. | P J Munson, D Rodbard | Anal Biochem | 1980 | 6254391 | Yes |
242 | 9802 | 4901.0 | 234.23 | 117.1 | A genetic model for colorectal tumorigenesis. | E R Fearon, B Vogelstein | Cell | 1990 | 2188735 | No |
243 | 4873 | 4873.0 | 110.21 | 110.2 | The clonal evolution of tumor cell populations. | P C Nowell | Science | 1976 | 959840 | Yes |
244 | 14603 | 4867.7 | 391.79 | 130.6 | Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. | C Yanisch-Perron, J Vieira, J Messing | Gene | 1985 | 2985470 | Yes |
245 | 4848 | 4848.0 | 97.73 | 97.7 | An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs. | M Kozak | Nucleic Acids Res | 1987 | 3313277 | No |
246 | 14467 | 4822.3 | 357.14 | 119.0 | A comprehensive set of sequence analysis programs for the VAX. | J Devereux, P Haeberli, O Smithies | Nucleic Acids Res | 1984 | 6546423 | Yes |
247 | 19195 | 4798.8 | 495.75 | 123.9 | Features and development of Coot. | P Emsley, B Lohkamp, W G Scott, K Cowtan | Acta Crystallogr D Biol Crystallogr | 2010 | 20383002 | Yes |
248 | 4785 | 4785.0 | 89.92 | 89.9 | DNA methylation patterns and epigenetic memory. | Adrian Bird | Genes Dev | 2002 | 11782440 | No |
249 | 14340 | 4780.0 | 0.0 | 0.0 | Determination of serum proteins by means of the biuret reaction. | A G Gornall, C J Bardawill, M M David | J Biol Chem | 1949 | 18110453 | Yes |
250 | 4773 | 4773.0 | 128.88 | 128.9 | Metabolism Of Isolated Fat Cells. I. Effects Of Hormones On Glucose Metabolism And Lipolysis. | M Rodbell | J Biol Chem | 1964 | 14169133 | Yes |
251 | 23853 | 4770.6 | 407.61 | 81.5 | An inventory for measuring depression. | A T Beck, C H Ward, M Mendelson, J Mock, J Erbaugh | Arch Gen Psychiatry | 1961 | 13688369 | Yes |
252 | 4758 | 4758.0 | 104.3 | 104.3 | Cancer cell cycles. | C J Sherr | Science | 1996 | 8939849 | No |
253 | 9509 | 4754.5 | 159.31 | 79.7 | A new technique for the assay of infectivity of human adenovirus 5 DNA. | F L Graham, A J van der Eb | Virology | 1973 | 4705382 | Yes |
254 | 4750 | 4750.0 | 106.48 | 106.5 | ras oncogenes in human cancer: a review. | J L Bos | Cancer Res | 1989 | 2547513 | No |
255 | 4748 | 4748.0 | 157.44 | 157.4 | Traumatic arthritis of the hip after dislocation and acetabular fractures: treatment by mold arthroplasty. An end-result study using a new method of result evaluation. | W H Harris | J Bone Joint Surg Am | 1969 | 5783851 | Yes |
256 | 9477 | 4738.5 | 257.25 | 128.6 | The rise of graphene. | A K Geim, K S Novoselov | Nat Mater | 2007 | 17330084 | Yes |
257 | 4708 | 4708.0 | 222.78 | 222.8 | Executive functions. | Adele Diamond | Annu Rev Psychol | 2013 | 23020641 | No |
258 | 9407 | 4703.5 | 237.39 | 118.7 | Improved tools for biological sequence comparison. | W R Pearson, D J Lipman | Proc Natl Acad Sci U S A | 1988 | 3162770 | Yes |
259 | 4703 | 4703.0 | 156.98 | 157.0 | The pathogenesis of atherosclerosis--an update. | R Ross | N Engl J Med | 1986 | 3511384 | No |
260 | 9357 | 4678.5 | 208.96 | 104.5 | Parkinsonism: onset, progression and mortality. | M M Hoehn, M D Yahr | Neurology | 1967 | 6067254 | Yes |
261 | 28039 | 4673.2 | 987.98 | 164.7 | Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support. | Paul A Harris, Robert Taylor, Robert Thielke, Jonathon Payne, Nathaniel Gonzalez, Jose G Conde | J Biomed Inform | 2009 | 18929686 | Yes |
262 | 4672 | 4672.0 | 103.59 | 103.6 | Alzheimer's disease: genes, proteins, and therapy. | D J Selkoe | Physiol Rev | 2001 | 11274343 | No |
263 | 4668 | 4668.0 | 129.73 | 129.7 | Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes. | P Matsudaira | J Biol Chem | 1987 | 3611052 | Yes |
264 | 4663 | 4663.0 | 72.28 | 72.3 | Aggregation of blood platelets by adenosine diphosphate and its reversal. | G V Born | Nature | 1962 | 13871375 | Yes |
265 | 13984 | 4661.3 | 1378.76 | 459.6 | Cancer statistics, 2020. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2020 | 31912902 | Yes |
266 | 4659 | 4659.0 | 211.9 | 211.9 | The McGill Pain Questionnaire: major properties and scoring methods. | Ronald Melzack | Pain | 1975 | 1235985 | Yes |
267 | 13950 | 4650.0 | 305.11 | 101.7 | Refinement of macromolecular structures by the maximum-likelihood method. | G N Murshudov, A A Vagin, E J Dodson | Acta Crystallogr D Biol Crystallogr | 1997 | 15299926 | Yes |
268 | 4641 | 4641.0 | 125.31 | 125.3 | A rapid banding technique for human chromosomes. | M Seabright | Lancet | 1971 | 4107917 | Yes |
269 | 13910 | 4636.7 | 480.37 | 160.1 | Nitric oxide: physiology, pathophysiology, and pharmacology. | S Moncada, R M Palmer, E A Higgs | Pharmacol Rev | 1991 | 1852778 | No |
270 | 18532 | 4633.0 | 534.86 | 133.7 | MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. | Koichiro Tamura, Joel Dudley, Masatoshi Nei, Sudhir Kumar | Mol Biol Evol | 2007 | 17488738 | Yes |
271 | 4615 | 4615.0 | 230.68 | 230.7 | Minimap2: pairwise alignment for nucleotide sequences. | Heng Li | Bioinformatics | 2018 | 29750242 | Yes |
272 | 4607 | 4607.0 | 102.28 | 102.3 | Prions. | S B Prusiner | Proc Natl Acad Sci U S A | 1998 | 9811807 | No |
273 | 9202 | 4601.0 | 183.18 | 91.6 | Assessment of older people: self-maintaining and instrumental activities of daily living. | M P Lawton, E M Brody | Gerontologist | 1969 | 5349366 | Yes |
274 | 4585 | 4585.0 | 40.31 | 40.3 | The Limited In Vitro Lifetime Of Human Diploid Cell Strains. | L Hayflick | Exp Cell Res | 1965 | 14315085 | Yes |
275 | 18328 | 4582.0 | 296.45 | 74.1 | A new and rapid colorimetric determination of acetylcholinesterase activity. | G L Ellman, K D Courtney, V Andres, R M Feather-Stone | Biochem Pharmacol | 1961 | 13726518 | Yes |
276 | 9095 | 4547.5 | 249.56 | 124.8 | Ab initio molecular dynamics for liquid metals. | G Kresse, J Hafner | Phys Rev B Condens Matter | 1993 | 10004490 | Yes |
277 | 9078 | 4539.0 | 310.36 | 155.2 | Qualitative content analysis in nursing research: concepts, procedures and measures to achieve trustworthiness. | U H Graneheim, B Lundman | Nurse Educ Today | 2004 | 14769454 | No |
278 | 4524 | 4524.0 | 97.85 | 97.8 | ras genes. | M Barbacid | Annu Rev Biochem | 1987 | 3304147 | No |
279 | 9047 | 4523.5 | 330.63 | 165.3 | Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models. | Kristopher J Preacher, Andrew F Hayes | Behav Res Methods | 2008 | 18697684 | Yes |
280 | 9043 | 4521.5 | 149.88 | 74.9 | Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). | J M McCord, I Fridovich | J Biol Chem | 1969 | 5389100 | Yes |
281 | 9040 | 4520.0 | 201.04 | 100.5 | Primer3 on the WWW for general users and for biologist programmers. | S Rozen, H Skaletsky | Methods Mol Biol | 2000 | 10547847 | Yes |
282 | 9031 | 4515.5 | 149.72 | 74.9 | Functional Evaluation: The Barthel Index. | F I Mahoney, D W Barthel | Md State Med J | 1965 | 14258950 | Yes |
283 | 4514 | 4514.0 | 93.2 | 93.2 | Alternative activation of macrophages. | Siamon Gordon | Nat Rev Immunol | 2003 | 12511873 | No |
284 | 4512 | 4512.0 | 106.37 | 106.4 | The genetical evolution of social behaviour. I. | W D Hamilton | J Theor Biol | 1964 | 5875341 | Yes |
285 | 4495 | 4495.0 | 140.66 | 140.7 | Updating P300: an integrative theory of P3a and P3b. | John Polich | Clin Neurophysiol | 2007 | 17573239 | No |
286 | 4474 | 4474.0 | 167.04 | 167.0 | FreeSurfer. | Bruce Fischl | Neuroimage | 2012 | 22248573 | No |
287 | 8925 | 4462.5 | 0.0 | 0.0 | A simplified method of evaluating dose-effect experiments. | J T Litchfield, F Wilcoxon | J Pharmacol Exp Ther | 1949 | 18152921 | Yes |
288 | 13386 | 4462.0 | 531.5 | 177.2 | A global measure of perceived stress. | S Cohen, T Kamarck, R Mermelstein | J Health Soc Behav | 1983 | 6668417 | Yes |
289 | 4455 | 4455.0 | 90.14 | 90.1 | Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. | M Kozak | Cell | 1986 | 3943125 | Yes |
290 | 13352 | 4450.7 | 588.13 | 196.0 | Development and validation of brief measures of positive and negative affect: the PANAS scales. | D Watson, L A Clark, A Tellegen | J Pers Soc Psychol | 1988 | 3397865 | Yes |
291 | 4445 | 4445.0 | 102.71 | 102.7 | Cancer. p53, guardian of the genome. | D P Lane | Nature | 1992 | 1614522 | No |
292 | 4445 | 4445.0 | 107.71 | 107.7 | A new method for predicting signal sequence cleavage sites. | G von Heijne | Nucleic Acids Res | 1986 | 3714490 | Yes |
293 | 26623 | 4437.2 | 930.23 | 155.0 | Global cancer statistics. | Ahmedin Jemal, Freddie Bray, Melissa M Center, Jacques Ferlay, Elizabeth Ward, David Forman | CA Cancer J Clin | 2011 | 21296855 | Yes |
294 | 8845 | 4422.5 | 211.53 | 105.8 | Collective dynamics of 'small-world' networks. | D J Watts, S H Strogatz | Nature | 1998 | 9623998 | Yes |
295 | 8841 | 4420.5 | 236.88 | 118.4 | A synaptic model of memory: long-term potentiation in the hippocampus. | T V Bliss, G L Collingridge | Nature | 1993 | 8421494 | No |
296 | 8782 | 4391.0 | 161.06 | 80.5 | A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels. | W M Bonner, R A Laskey | Eur J Biochem | 1974 | 4850204 | Yes |
297 | 8770 | 4385.0 | 221.82 | 110.9 | Assessment of coma and impaired consciousness. A practical scale. | G Teasdale, B Jennett | Lancet | 1974 | 4136544 | Yes |
298 | 8731 | 4365.5 | 201.71 | 100.9 | SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. | N Guex, M C Peitsch | Electrophoresis | 1997 | 9504803 | Yes |
299 | 4361 | 4361.0 | 89.99 | 90.0 | Wnt/beta-catenin signaling in development and disease. | Hans Clevers | Cell | 2006 | 17081971 | No |
300 | 4359 | 4359.0 | 83.45 | 83.5 | The phosphoinositide 3-kinase pathway. | Lewis C Cantley | Science | 2002 | 12040186 | No |
301 | 4354 | 4354.0 | 218.93 | 218.9 | Tetramethyl benzidine for horseradish peroxidase neurohistochemistry: a non-carcinogenic blue reaction product with superior sensitivity for visualizing neural afferents and efferents. | M M Mesulam | J Histochem Cytochem | 1978 | 24068 | Yes |
302 | 4353 | 4353.0 | 112.33 | 112.3 | Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. | Y Nishizuka | Science | 1992 | 1411571 | No |
303 | 4352 | 4352.0 | 103.56 | 103.6 | Why most published research findings are false. | John P A Ioannidis | PLoS Med | 2005 | 16060722 | Yes |
304 | 25940 | 4323.3 | 959.85 | 160.0 | MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. | Koichiro Tamura, Daniel Peterson, Nicholas Peterson, Glen Stecher, Masatoshi Nei, Sudhir Kumar | Mol Biol Evol | 2011 | 21546353 | Yes |
305 | 12959 | 4319.7 | 653.04 | 217.7 | Cancer statistics, 2016. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2016 | 26742998 | Yes |
306 | 4313 | 4313.0 | 101.2 | 101.2 | Mechanisms of angiogenesis. | W Risau | Nature | 1997 | 9109485 | No |
307 | 4304 | 4304.0 | 129.22 | 129.2 | Glutamate neurotoxicity and diseases of the nervous system. | D W Choi | Neuron | 1988 | 2908446 | No |
308 | 8606 | 4303.0 | 116.72 | 58.4 | Preparation of iodine-131 labelled human growth hormone of high specific activity. | W M Hunter, F C Greenwood | Nature | 1962 | 14450081 | Yes |
309 | 8602 | 4301.0 | 232.11 | 116.1 | Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetii. | Daniel E Voth, Robert A Heinzen | Cell Microbiol | 2007 | 17381428 | No |
310 | 4281 | 4281.0 | 113.6 | 113.6 | The molecular heterogeneity of protein kinase C and its implications for cellular regulation. | Y Nishizuka | Nature | 1988 | 3045562 | No |
311 | 4281 | 4281.0 | 93.04 | 93.0 | Apoptosis by death factor. | S Nagata | Cell | 1997 | 9039262 | No |
312 | 4270 | 4270.0 | 155.74 | 155.7 | EuroQol: the current state of play. | R Brooks | Health Policy | 1996 | 10158943 | No |
313 | 4259 | 4259.0 | 110.47 | 110.5 | Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. | A H Wyllie | Nature | 1980 | 6245367 | Yes |
314 | 4257 | 4257.0 | 80.31 | 80.3 | The detection of disease clustering and a generalized regression approach. | N Mantel | Cancer Res | 1967 | 6018555 | Yes |
315 | 4244 | 4244.0 | 0.0 | 0.0 | Evolution in Mendelian Populations. | S Wright | Genetics | 1931 | 17246615 | Yes |
316 | 4236 | 4236.0 | 0.0 | 0.0 | Estimation of nuclear population from microtome sections. | M Abercrombie | Anat Rec | 1946 | 21015608 | Yes |
317 | 4234 | 4234.0 | 0.0 | 0.0 | The colorimetric estimation of formaldehyde by means of the Hantzsch reaction. | T Nash | Biochem J | 1953 | 13105648 | Yes |
318 | 12690 | 4230.0 | 406.97 | 135.7 | Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. | E R DeLong, D M DeLong, D L Clarke-Pearson | Biometrics | 1988 | 3203132 | Yes |
319 | 4227 | 4227.0 | 0.0 | 0.0 | Amino acid metabolism in mammalian cell cultures. | H Eagle | Science | 1959 | 13675766 | Yes |
320 | 8453 | 4226.5 | 244.28 | 122.1 | Estimating F-Statistics For The Analysis Of Population Structure. | B S Weir, C Clark Cockerham | Evolution | 1984 | 28563791 | Yes |
321 | 4222 | 4222.0 | 87.43 | 87.4 | The retinoblastoma protein and cell cycle control. | R A Weinberg | Cell | 1995 | 7736585 | No |
322 | 4222 | 4222.0 | 0.0 | 0.0 | New methods for calculating metabolic rate with special reference to protein metabolism. | J B De B Weir | J Physiol | 1949 | 15394301 | Yes |
323 | 4217 | 4217.0 | 93.77 | 93.8 | Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing. | S Henikoff | Gene | 1984 | 6235151 | Yes |
324 | 12645 | 4215.0 | 787.56 | 262.5 | Cancer statistics, 2018. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2018 | 29313949 | Yes |
325 | 8407 | 4203.5 | 311.59 | 155.8 | The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay. | I F Benzie, J J Strain | Anal Biochem | 1996 | 8660627 | Yes |
326 | 4201 | 4201.0 | 0.0 | 0.0 | A relation between non-esterified fatty acids in plasma and the metabolism of glucose. | V P Dole | J Clin Invest | 1956 | 13286333 | Yes |
327 | 12599 | 4199.7 | 465.2 | 155.1 | HTSeq--a Python framework to work with high-throughput sequencing data. | Simon Anders, Paul Theodor Pyl, Wolfgang Huber | Bioinformatics | 2015 | 25260700 | Yes |
328 | 8391 | 4195.5 | 347.72 | 173.9 | The timed "Up & Go": a test of basic functional mobility for frail elderly persons. | D Podsiadlo, S Richardson | J Am Geriatr Soc | 1991 | 1991946 | Yes |
329 | 4182 | 4182.0 | 87.16 | 87.2 | Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. | C J Marshall | Cell | 1995 | 7834738 | No |
330 | 4182 | 4182.0 | 90.98 | 91.0 | Atherosclerosis. | A J Lusis | Nature | 2000 | 11001066 | No |
331 | 4181 | 4181.0 | 75.63 | 75.6 | Generalized lacZ expression with the ROSA26 Cre reporter strain. | P Soriano | Nat Genet | 1999 | 9916792 | Yes |
332 | 8356 | 4178.0 | 350.16 | 175.1 | phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data. | Paul J McMurdie, Susan Holmes | PLoS One | 2013 | 23630581 | Yes |
333 | 8327 | 4163.5 | 0.0 | 0.0 | Radiological assessment of osteo-arthrosis. | J H Kellgren, J S Lawrence | Ann Rheum Dis | 1957 | 13498604 | Yes |
334 | 4162 | 4162.0 | 88.93 | 88.9 | Protein production by auto-induction in high density shaking cultures. | F William Studier | Protein Expr Purif | 2005 | 15915565 | Yes |
335 | 24963 | 4160.5 | 814.46 | 135.7 | Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. | D R Matthews, J P Hosker, A S Rudenski, B A Naylor, D F Treacher, R C Turner | Diabetologia | 1985 | 3899825 | Yes |
336 | 4156 | 4156.0 | 155.76 | 155.8 | Measuring the accuracy of diagnostic systems. | J A Swets | Science | 1988 | 3287615 | No |
337 | 4154 | 4154.0 | 50.44 | 50.4 | Bone: formation by autoinduction. | M R Urist | Science | 1965 | 5319761 | Yes |
338 | 12429 | 4143.0 | 553.71 | 184.6 | Deep learning. | Yann LeCun, Yoshua Bengio, Geoffrey Hinton | Nature | 2015 | 26017442 | No |
339 | 4142 | 4142.0 | 166.85 | 166.8 | Determination of protein: a modification of the Lowry method that gives a linear photometric response. | E F Hartree | Anal Biochem | 1972 | 4115981 | Yes |
340 | 8278 | 4139.0 | 177.46 | 88.7 | Genomic sequencing. | G M Church, W Gilbert | Proc Natl Acad Sci U S A | 1984 | 6326095 | Yes |
341 | 4134 | 4134.0 | 0.0 | 0.0 | The determination of enzyme inhibitor constants. | M Dixon | Biochem J | 1953 | 13093635 | Yes |
342 | 4124 | 4124.0 | 91.63 | 91.6 | PAML: a program package for phylogenetic analysis by maximum likelihood. | Z Yang | Comput Appl Biosci | 1997 | 9367129 | Yes |
343 | 4115 | 4115.0 | 107.33 | 107.3 | Staphylococcus aureus infections. | F D Lowy | N Engl J Med | 1998 | 9709046 | No |
344 | 4093 | 4093.0 | 110.66 | 110.7 | Mesenchymal stem cells. | A I Caplan | J Orthop Res | 1991 | 1870029 | Yes |
345 | 12262 | 4087.3 | 454.19 | 151.4 | A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. | J Ware, M Kosinski, S D Keller | Med Care | 1996 | 8628042 | Yes |
346 | 4082 | 4082.0 | 127.62 | 127.6 | Bacterial evolution. | C R Woese | Microbiol Rev | 1987 | 2439888 | No |
347 | 8118 | 4059.0 | 210.35 | 105.2 | Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. | D E Paglia, W N Valentine | J Lab Clin Med | 1967 | 6066618 | Yes |
348 | 16226 | 4056.5 | 518.5 | 129.6 | A consistent and accurate ab initio parametrization of density functional dispersion correction (DFT-D) for the 94 elements H-Pu. | Stefan Grimme, Jens Antony, Stephan Ehrlich, Helge Krieg | J Chem Phys | 2010 | 20423165 | Yes |
349 | 8098 | 4049.0 | 260.35 | 130.2 | DnaSP v5: a software for comprehensive analysis of DNA polymorphism data. | P Librado, J Rozas | Bioinformatics | 2009 | 19346325 | Yes |
350 | 16190 | 4047.5 | 611.39 | 152.8 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | Ann Intern Med | 2009 | 19622511 | No |
351 | 4041 | 4041.0 | 173.9 | 173.9 | A short portable mental status questionnaire for the assessment of organic brain deficit in elderly patients. | E Pfeiffer | J Am Geriatr Soc | 1975 | 1159263 | Yes |
352 | 4037 | 4037.0 | 83.95 | 84.0 | The green fluorescent protein. | R Y Tsien | Annu Rev Biochem | 1998 | 9759496 | No |
353 | 28184 | 4026.3 | 622.33 | 88.9 | UCSF Chimera--a visualization system for exploratory research and analysis. | Eric F Pettersen, Thomas D Goddard, Conrad C Huang, Gregory S Couch, Daniel M Greenblatt, Elaine C Meng, Thomas E Ferrin | J Comput Chem | 2004 | 15264254 | Yes |
354 | 4017 | 4017.0 | 103.55 | 103.5 | Integrins: a family of cell surface receptors. | R O Hynes | Cell | 1987 | 3028640 | No |
355 | 12029 | 4009.7 | 649.45 | 216.5 | Cancer Statistics, 2017. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2017 | 28055103 | Yes |
356 | 4001 | 4001.0 | 101.6 | 101.6 | The Scree Test For The Number Of Factors. | R B Cattell | Multivariate Behav Res | 1966 | 26828106 | Yes |
357 | 7986 | 3993.0 | 204.13 | 102.1 | tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence. | T M Lowe, S R Eddy | Nucleic Acids Res | 1997 | 9023104 | Yes |
358 | 3983 | 3983.0 | 106.88 | 106.9 | What is the evidence that tumors are angiogenesis dependent? | J Folkman | J Natl Cancer Inst | 1990 | 1688381 | No |
359 | 3981 | 3981.0 | 78.53 | 78.5 | Hypoxia--a key regulatory factor in tumour growth. | Adrian L Harris | Nat Rev Cancer | 2002 | 11902584 | No |
360 | 3978 | 3978.0 | 128.08 | 128.1 | Tissue destruction by neutrophils. | S J Weiss | N Engl J Med | 1989 | 2536474 | No |
361 | 3969 | 3969.0 | 0.0 | 0.0 | Staining of tissue sections for electron microscopy with heavy metals. | M L Watson | J Biophys Biochem Cytol | 1958 | 13563554 | Yes |
362 | 3965 | 3965.0 | 115.84 | 115.8 | Soft self-consistent pseudopotentials in a generalized eigenvalue formalism. | D Vanderbilt | Phys Rev B Condens Matter | 1990 | 9993096 | Yes |
363 | 3963 | 3963.0 | 146.66 | 146.7 | A concordance correlation coefficient to evaluate reproducibility. | L I Lin | Biometrics | 1989 | 2720055 | Yes |
364 | 3955 | 3955.0 | 127.22 | 127.2 | Weighted kappa: nominal scale agreement with provision for scaled disagreement or partial credit. | J Cohen | Psychol Bull | 1968 | 19673146 | Yes |
365 | 3953 | 3953.0 | 125.71 | 125.7 | How do you feel--now? The anterior insula and human awareness. | A D Bud Craig | Nat Rev Neurosci | 2009 | 19096369 | No |
366 | 3952 | 3952.0 | 69.86 | 69.9 | Principles that govern the folding of protein chains. | C B Anfinsen | Science | 1973 | 4124164 | Yes |
367 | 3939 | 3939.0 | 122.88 | 122.9 | Emerging adulthood. A theory of development from the late teens through the twenties. | J J Arnett | Am Psychol | 2000 | 10842426 | Yes |
368 | 7874 | 3937.0 | 148.19 | 74.1 | A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. | R S Sikorski, P Hieter | Genetics | 1989 | 2659436 | Yes |
369 | 15744 | 3936.0 | 578.05 | 144.5 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | BMJ | 2009 | 19622551 | No |
370 | 3931 | 3931.0 | 144.26 | 144.3 | Disc Electrophoresis. I. Background And Theory. | L Ornstein | Ann N Y Acad Sci | 1964 | 14240533 | Yes |
371 | 7854 | 3927.0 | 212.29 | 106.1 | Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose. | H Aviv, P Leder | Proc Natl Acad Sci U S A | 1972 | 4504350 | Yes |
372 | 3925 | 3925.0 | 96.62 | 96.6 | Multiple sequence alignment with hierarchical clustering. | F Corpet | Nucleic Acids Res | 1988 | 2849754 | Yes |
373 | 3901 | 3901.0 | 120.29 | 120.3 | Nitric oxide as a secretory product of mammalian cells. | C Nathan | FASEB J | 1992 | 1381691 | No |
374 | 11690 | 3896.7 | 299.06 | 99.7 | Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. | W H Habig, M J Pabst, W B Jakoby | J Biol Chem | 1974 | 4436300 | Yes |
375 | 11680 | 3893.3 | 304.71 | 101.6 | Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. | J F Kerr, A H Wyllie, A R Currie | Br J Cancer | 1972 | 4561027 | No |
376 | 3893 | 3893.0 | 98.73 | 98.7 | Oxidative stress, antioxidants and stress tolerance. | Ron Mittler | Trends Plant Sci | 2002 | 12234732 | No |
377 | 7767 | 3883.5 | 197.81 | 98.9 | Control of goal-directed and stimulus-driven attention in the brain. | Maurizio Corbetta, Gordon L Shulman | Nat Rev Neurosci | 2002 | 11994752 | No |
378 | 3875 | 3875.0 | 80.19 | 80.2 | Protein secondary structure prediction based on position-specific scoring matrices. | D T Jones | J Mol Biol | 1999 | 10493868 | Yes |
379 | 7747 | 3873.5 | 215.75 | 107.9 | Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. | S Duval, R Tweedie | Biometrics | 2000 | 10877304 | Yes |
380 | 3873 | 3873.0 | 125.29 | 125.3 | Preparation of isolated rat liver cells. | P O Seglen | Methods Cell Biol | 1976 | 177845 | No |
381 | 3873 | 3873.0 | 186.71 | 186.7 | Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs. | Daniël Lakens | Front Psychol | 2013 | 24324449 | No |
382 | 3872 | 3872.0 | 119.13 | 119.1 | Pharmacological implications of microsomal enzyme induction. | A H Conney | Pharmacol Rev | 1967 | 4383307 | Yes |
383 | 3864 | 3864.0 | 83.76 | 83.8 | Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. | Rakesh K Jain | Science | 2005 | 15637262 | No |
384 | 3860 | 3860.0 | 103.0 | 103.0 | Propensity score methods for bias reduction in the comparison of a treatment to a non-randomized control group. | R B D'Agostino | Stat Med | 1998 | 9802183 | Yes |
385 | 15437 | 3859.2 | 467.87 | 117.0 | clusterProfiler: an R package for comparing biological themes among gene clusters. | Guangchuang Yu, Li-Gen Wang, Yanyan Han, Qing-Yu He | OMICS | 2012 | 22455463 | Yes |
386 | 7708 | 3854.0 | 290.22 | 145.1 | Multiwfn: a multifunctional wavefunction analyzer. | Tian Lu, Feiwu Chen | J Comput Chem | 2012 | 22162017 | Yes |
387 | 3847 | 3847.0 | 102.12 | 102.1 | Observational study of behavior: sampling methods. | J Altmann | Behaviour | 1974 | 4597405 | No |
388 | 3847 | 3847.0 | 127.91 | 127.9 | Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD. | Russell A Barkley | Psychol Bull | 1997 | 9000892 | No |
389 | 11539 | 3846.3 | 385.22 | 128.4 | featureCounts: an efficient general purpose program for assigning sequence reads to genomic features. | Yang Liao, Gordon K Smyth, Wei Shi | Bioinformatics | 2014 | 24227677 | Yes |
390 | 34506 | 3834.0 | 879.06 | 97.7 | The Sequence Alignment/Map format and SAMtools. | Heng Li, Bob Handsaker, Alec Wysoker, Tim Fennell, Jue Ruan, Nils Homer, Gabor Marth, Goncalo Abecasis, Richard Durbin | Bioinformatics | 2009 | 19505943 | Yes |
391 | 7660 | 3830.0 | 144.66 | 72.3 | Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. | A H Brand, N Perrimon | Development | 1993 | 8223268 | Yes |
392 | 3819 | 3819.0 | 90.96 | 91.0 | Caspases: the executioners of apoptosis. | G M Cohen | Biochem J | 1997 | 9337844 | No |
393 | 3816 | 3816.0 | 83.65 | 83.7 | Folding DNA to create nanoscale shapes and patterns. | Paul W K Rothemund | Nature | 2006 | 16541064 | Yes |
394 | 3807 | 3807.0 | 102.7 | 102.7 | Revisions in the International System for Staging Lung Cancer. | C F Mountain | Chest | 1997 | 9187198 | Yes |
395 | 3797 | 3797.0 | 97.95 | 98.0 | Sequencing technologies - the next generation. | Michael L Metzker | Nat Rev Genet | 2010 | 19997069 | No |
396 | 3792 | 3792.0 | 80.16 | 80.2 | A catalogue of splice junction sequences. | S M Mount | Nucleic Acids Res | 1982 | 7063411 | Yes |
397 | 3781 | 3781.0 | 96.82 | 96.8 | Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? | Kim A Brogden | Nat Rev Microbiol | 2005 | 15703760 | No |
398 | 3777 | 3777.0 | 84.06 | 84.1 | Instability and decay of the primary structure of DNA. | T Lindahl | Nature | 1993 | 8469282 | No |
399 | 7552 | 3776.0 | 182.36 | 91.2 | Mitochondria and apoptosis. | D R Green, J C Reed | Science | 1998 | 9721092 | No |
400 | 3774 | 3774.0 | 73.78 | 73.8 | Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. | G R Martin | Proc Natl Acad Sci U S A | 1981 | 6950406 | Yes |
401 | 3771 | 3771.0 | 77.54 | 77.5 | TGF-beta signal transduction. | J Massagué | Annu Rev Biochem | 1998 | 9759503 | No |
402 | 3761 | 3761.0 | 146.86 | 146.9 | Estimation of the molecular weights of proteins by Sephadex gel-filtration. | P Andrews | Biochem J | 1964 | 4158310 | Yes |
403 | 3752 | 3752.0 | 107.08 | 107.1 | Silver stain for proteins in polyacrylamide gels: a modified procedure with enhanced uniform sensitivity. | J H Morrissey | Anal Biochem | 1981 | 6172996 | Yes |
404 | 3752 | 3752.0 | 94.32 | 94.3 | The origins and the future of microfluidics. | George M Whitesides | Nature | 2006 | 16871203 | No |
405 | 14999 | 3749.8 | 353.28 | 88.3 | Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. | Ben Langmead, Cole Trapnell, Mihai Pop, Steven L Salzberg | Genome Biol | 2009 | 19261174 | Yes |
406 | 3742 | 3742.0 | 100.68 | 100.7 | Drug combination studies and their synergy quantification using the Chou-Talalay method. | Ting-Chao Chou | Cancer Res | 2010 | 20068163 | Yes |
407 | 11225 | 3741.7 | 215.45 | 71.8 | Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. | J D Dignam, R M Lebovitz, R G Roeder | Nucleic Acids Res | 1983 | 6828386 | Yes |
408 | 3739 | 3739.0 | 88.96 | 89.0 | Free R value: a novel statistical quantity for assessing the accuracy of crystal structures. | A T Brünger | Nature | 1992 | 18481394 | Yes |
409 | 3734 | 3734.0 | 86.68 | 86.7 | Novel proteinaceous infectious particles cause scrapie. | S B Prusiner | Science | 1982 | 6801762 | Yes |
410 | 3733 | 3733.0 | 107.93 | 107.9 | What's wrong with Bonferroni adjustments. | T V Perneger | BMJ | 1998 | 9553006 | No |
411 | 3733 | 3733.0 | 79.8 | 79.8 | Scaling and assessment of data quality. | Philip Evans | Acta Crystallogr D Biol Crystallogr | 2006 | 16369096 | No |
412 | 3728 | 3728.0 | 107.21 | 107.2 | Functions of DNA methylation: islands, start sites, gene bodies and beyond. | Peter A Jones | Nat Rev Genet | 2012 | 22641018 | No |
413 | 3717 | 3717.0 | 117.56 | 117.6 | genepop'007: a complete re-implementation of the genepop software for Windows and Linux. | François Rousset | Mol Ecol Resour | 2008 | 21585727 | Yes |
414 | 14860 | 3715.0 | 384.22 | 96.1 | Global cancer statistics, 2002. | D Max Parkin, Freddie Bray, J Ferlay, Paola Pisani | CA Cancer J Clin | 2005 | 15761078 | Yes |
415 | 7429 | 3714.5 | 207.69 | 103.8 | BEAST: Bayesian evolutionary analysis by sampling trees. | Alexei J Drummond, Andrew Rambaut | BMC Evol Biol | 2007 | 17996036 | Yes |
416 | 3705 | 3705.0 | 61.48 | 61.5 | A membrane-filter technique for the detection of complementary DNA. | D T Denhardt | Biochem Biophys Res Commun | 1966 | 5963888 | Yes |
417 | 3700 | 3700.0 | 167.67 | 167.7 | Basic principles of ROC analysis. | C E Metz | Semin Nucl Med | 1978 | 112681 | Yes |
418 | 3698 | 3698.0 | 66.96 | 67.0 | Somatic generation of antibody diversity. | S Tonegawa | Nature | 1983 | 6300689 | No |
419 | 3698 | 3698.0 | 91.89 | 91.9 | Origin and physiological roles of inflammation. | Ruslan Medzhitov | Nature | 2008 | 18650913 | No |
420 | 7388 | 3694.0 | 183.92 | 92.0 | Fast and accurate long-read alignment with Burrows-Wheeler transform. | Heng Li, Richard Durbin | Bioinformatics | 2010 | 20080505 | Yes |
421 | 3692 | 3692.0 | 125.74 | 125.7 | Generalized expectancies for internal versus external control of reinforcement. | J B Rotter | Psychol Monogr | 1966 | 5340840 | No |
422 | 11044 | 3681.3 | 428.77 | 142.9 | HISAT: a fast spliced aligner with low memory requirements. | Daehwan Kim, Ben Langmead, Steven L Salzberg | Nat Methods | 2015 | 25751142 | Yes |
423 | 7342 | 3671.0 | 161.84 | 80.9 | Functional rafts in cell membranes. | K Simons, E Ikonen | Nature | 1997 | 9177342 | No |
424 | 7324 | 3662.0 | 186.54 | 93.3 | The basics of epithelial-mesenchymal transition. | Raghu Kalluri, Robert A Weinberg | J Clin Invest | 2009 | 19487818 | No |
425 | 18238 | 3647.6 | 707.94 | 141.6 | The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. | D J Buysse, C F Reynolds, T H Monk, S R Berman, D J Kupfer | Psychiatry Res | 1989 | 2748771 | Yes |
426 | 3646 | 3646.0 | 105.37 | 105.4 | Protective and damaging effects of stress mediators. | B S McEwen | N Engl J Med | 1998 | 9428819 | No |
427 | 3644 | 3644.0 | 100.92 | 100.9 | Biological roles of oligosaccharides: all of the theories are correct. | A Varki | Glycobiology | 1993 | 8490246 | No |
428 | 7279 | 3639.5 | 161.92 | 81.0 | Inference of macromolecular assemblies from crystalline state. | Evgeny Krissinel, Kim Henrick | J Mol Biol | 2007 | 17681537 | Yes |
429 | 7269 | 3634.5 | 246.45 | 123.2 | FLASH: fast length adjustment of short reads to improve genome assemblies. | Tanja Magoč, Steven L Salzberg | Bioinformatics | 2011 | 21903629 | Yes |
430 | 3630 | 3630.0 | 88.5 | 88.5 | I-TASSER server for protein 3D structure prediction. | Yang Zhang | BMC Bioinformatics | 2008 | 18215316 | Yes |
431 | 3629 | 3629.0 | 103.31 | 103.3 | Graphene: status and prospects. | A K Geim | Science | 2009 | 19541989 | Yes |
432 | 7250 | 3625.0 | 183.87 | 91.9 | The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique. | R C Graham, M J Karnovsky | J Histochem Cytochem | 1966 | 5962951 | Yes |
433 | 3619 | 3619.0 | 108.58 | 108.6 | Inositol trisphosphate and diacylglycerol as second messengers. | M J Berridge | Biochem J | 1984 | 6146314 | No |
434 | 3614 | 3614.0 | 101.48 | 101.5 | EEG alpha and theta oscillations reflect cognitive and memory performance: a review and analysis. | W Klimesch | Brain Res Brain Res Rev | 1999 | 10209231 | No |
435 | 7214 | 3607.0 | 181.91 | 91.0 | An integrative theory of prefrontal cortex function. | E K Miller, J D Cohen | Annu Rev Neurosci | 2001 | 11283309 | No |
436 | 7212 | 3606.0 | 250.96 | 125.5 | Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. | Laurent Excoffier, Heidi E L Lischer | Mol Ecol Resour | 2010 | 21565059 | Yes |
437 | 7208 | 3604.0 | 173.84 | 86.9 | The plant immune system. | Jonathan D G Jones, Jeffery L Dangl | Nature | 2006 | 17108957 | No |
438 | 3592 | 3592.0 | 84.51 | 84.5 | Marrow stromal cells as stem cells for nonhematopoietic tissues. | D J Prockop | Science | 1997 | 9082988 | No |
439 | 3590 | 3590.0 | 93.71 | 93.7 | The adolescent brain and age-related behavioral manifestations. | L P Spear | Neurosci Biobehav Rev | 2000 | 10817843 | No |
440 | 21538 | 3589.7 | 1005.68 | 167.6 | Global cancer statistics, 2012. | Lindsey A Torre, Freddie Bray, Rebecca L Siegel, Jacques Ferlay, Joannie Lortet-Tieulent, Ahmedin Jemal | CA Cancer J Clin | 2015 | 25651787 | Yes |
441 | 3589 | 3589.0 | 84.56 | 84.6 | Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. | Ting-Chao Chou | Pharmacol Rev | 2006 | 16968952 | No |
442 | 7134 | 3567.0 | 287.7 | 143.8 | The qualitative content analysis process. | Satu Elo, Helvi Kyngäs | J Adv Nurs | 2008 | 18352969 | Yes |
443 | 3545 | 3545.0 | 71.17 | 71.2 | Mammalian neural stem cells. | F H Gage | Science | 2000 | 10688783 | No |
444 | 7050 | 3525.0 | 355.47 | 177.7 | Microsomal lipid peroxidation. | J A Buege, S D Aust | Methods Enzymol | 1978 | 672633 | Yes |
445 | 3524 | 3524.0 | 95.11 | 95.1 | A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data. | Heng Li | Bioinformatics | 2011 | 21903627 | Yes |
446 | 10556 | 3518.7 | 257.37 | 85.8 | Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. | Da Wei Huang, Brad T Sherman, Richard A Lempicki | Nucleic Acids Res | 2009 | 19033363 | Yes |
447 | 3518 | 3518.0 | 73.62 | 73.6 | Profile hidden Markov models. | S R Eddy | Bioinformatics | 1998 | 9918945 | No |
448 | 3516 | 3516.0 | 66.91 | 66.9 | Signal transduction by the JNK group of MAP kinases. | R J Davis | Cell | 2000 | 11057897 | No |
449 | 3515 | 3515.0 | 161.23 | 161.2 | Estimation of average heterozygosity and genetic distance from a small number of individuals. | M Nei | Genetics | 1978 | 17248844 | Yes |
450 | 7026 | 3513.0 | 146.32 | 73.2 | A new method for sequencing DNA. | A M Maxam, W Gilbert | Proc Natl Acad Sci U S A | 1977 | 265521 | Yes |
451 | 3509 | 3509.0 | 90.82 | 90.8 | Microglia: a sensor for pathological events in the CNS. | G W Kreutzberg | Trends Neurosci | 1996 | 8843599 | No |
452 | 17522 | 3504.4 | 495.21 | 99.0 | Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. | O P Hamill, A Marty, E Neher, B Sakmann, F J Sigworth | Pflugers Arch | 1981 | 6270629 | Yes |
453 | 3504 | 3504.0 | 54.32 | 54.3 | Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. | J D Rowley | Nature | 1973 | 4126434 | Yes |
454 | 3504 | 3504.0 | 79.81 | 79.8 | Nonalcoholic fatty liver disease. | Paul Angulo | N Engl J Med | 2002 | 11961152 | No |
455 | 7000 | 3500.0 | 127.31 | 63.7 | Translating the histone code. | T Jenuwein, C D Allis | Science | 2001 | 11498575 | No |
456 | 3500 | 3500.0 | 101.55 | 101.5 | Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity-score matched samples. | Peter C Austin | Stat Med | 2009 | 19757444 | Yes |
457 | 3498 | 3498.0 | 104.52 | 104.5 | Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans. | L R Squire | Psychol Rev | 1992 | 1594723 | No |
458 | 3496 | 3496.0 | 59.03 | 59.0 | Statistical estimations in enzyme kinetics. | G N Wilkinson | Biochem J | 1961 | 13785321 | Yes |
459 | 3494 | 3494.0 | 55.01 | 55.0 | Spectroscopic determination of tryptophan and tyrosine in proteins. | H Edelhoch | Biochemistry | 1967 | 6049437 | Yes |
460 | 3492 | 3492.0 | 80.25 | 80.2 | Glutamate uptake. | N C Danbolt | Prog Neurobiol | 2001 | 11369436 | No |
461 | 3491 | 3491.0 | 81.4 | 81.4 | The dendritic cell system and its role in immunogenicity. | R M Steinman | Annu Rev Immunol | 1991 | 1910679 | No |
462 | 3475 | 3475.0 | 111.78 | 111.8 | Modeling valuations for EuroQol health states. | P Dolan | Med Care | 1997 | 9366889 | Yes |
463 | 3472 | 3472.0 | 84.89 | 84.9 | The heat-shock response. | S Lindquist | Annu Rev Biochem | 1986 | 2427013 | No |
464 | 3472 | 3472.0 | 51.91 | 51.9 | The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. | J F Woessner | Arch Biochem Biophys | 1961 | 13786180 | Yes |
465 | 6938 | 3469.0 | 77.49 | 38.7 | Receptive fields, binocular interaction and functional architecture in the cat's visual cortex. | D H Hubel, T N Wiesel | J Physiol | 1962 | 14449617 | Yes |
466 | 3467 | 3467.0 | 96.07 | 96.1 | Non-coding RNAs in human disease. | Manel Esteller | Nat Rev Genet | 2011 | 22094949 | No |
467 | 3461 | 3461.0 | 102.06 | 102.1 | Accelerated Profile HMM Searches. | Sean R Eddy | PLoS Comput Biol | 2011 | 22039361 | Yes |
468 | 3460 | 3460.0 | 82.77 | 82.8 | Neural networks and physical systems with emergent collective computational abilities. | J J Hopfield | Proc Natl Acad Sci U S A | 1982 | 6953413 | Yes |
469 | 10378 | 3459.3 | 399.68 | 133.2 | Cancer statistics, 2013. | Rebecca Siegel, Deepa Naishadham, Ahmedin Jemal | CA Cancer J Clin | 2013 | 23335087 | Yes |
470 | 3448 | 3448.0 | 134.52 | 134.5 | Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. | O W Griffith | Anal Biochem | 1980 | 7416462 | Yes |
471 | 3440 | 3440.0 | 88.54 | 88.5 | RELION: implementation of a Bayesian approach to cryo-EM structure determination. | Sjors H W Scheres | J Struct Biol | 2012 | 23000701 | Yes |
472 | 6877 | 3438.5 | 162.6 | 81.3 | "A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum. | A P Feinberg, B Vogelstein | Anal Biochem | 1984 | 6329026 | Yes |
473 | 3438 | 3438.0 | 106.17 | 106.2 | Health promotion by social cognitive means. | Albert Bandura | Health Educ Behav | 2004 | 15090118 | Yes |
474 | 3429 | 3429.0 | 93.61 | 93.6 | Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. | R W Mahley | Science | 1988 | 3283935 | No |
475 | 6838 | 3419.0 | 173.67 | 86.8 | TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. | T R Mosmann, R L Coffman | Annu Rev Immunol | 1989 | 2523712 | No |
476 | 3419 | 3419.0 | 74.34 | 74.3 | Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. | H F Dvorak | N Engl J Med | 1986 | 3537791 | No |
477 | 3418 | 3418.0 | 85.42 | 85.4 | The pathobiology of diabetic complications: a unifying mechanism. | Michael Brownlee | Diabetes | 2005 | 15919781 | No |
478 | 3416 | 3416.0 | 84.72 | 84.7 | How do you feel? Interoception: the sense of the physiological condition of the body. | A D Craig | Nat Rev Neurosci | 2002 | 12154366 | No |
479 | 3416 | 3416.0 | 0.0 | 0.0 | The magical number seven plus or minus two: some limits on our capacity for processing information. | G A Miller | Psychol Rev | 1956 | 13310704 | Yes |
480 | 10240 | 3413.3 | 464.31 | 154.8 | Cancer statistics, 2015. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2015 | 25559415 | Yes |
481 | 3411 | 3411.0 | 96.71 | 96.7 | Room-Temperature Ionic Liquids. Solvents for Synthesis and Catalysis. | Thomas Welton | Chem Rev | 1999 | 11849019 | Yes |
482 | 3401 | 3401.0 | 0.0 | 0.0 | Some factors in the interpretation of protein denaturation. | W Kauzmann | Adv Protein Chem | 1959 | 14404936 | Yes |
483 | 13591 | 3397.8 | 438.31 | 109.6 | A brief measure for assessing generalized anxiety disorder: the GAD-7. | Robert L Spitzer, Kurt Kroenke, Janet B W Williams, Bernd Löwe | Arch Intern Med | 2006 | 16717171 | Yes |
484 | 3397 | 3397.0 | 107.64 | 107.6 | DNA methylation age of human tissues and cell types. | Steve Horvath | Genome Biol | 2013 | 24138928 | Yes |
485 | 3396 | 3396.0 | 85.78 | 85.8 | Biologic basis for interleukin-1 in disease. | C A Dinarello | Blood | 1996 | 8630372 | No |
486 | 10164 | 3388.0 | 70.21 | 23.4 | The Preparation Of I-131-Labelled Human Growth Hormone Of High Specific Radioactivity. | F C Greenwood, W M Hunter, J S Glover | Biochem J | 1963 | 14097352 | Yes |
487 | 10137 | 3379.0 | 252.52 | 84.2 | Understanding the Warburg effect: the metabolic requirements of cell proliferation. | Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson | Science | 2009 | 19460998 | No |
488 | 6739 | 3369.5 | 171.46 | 85.7 | Long short-term memory. | S Hochreiter, J Schmidhuber | Neural Comput | 1997 | 9377276 | Yes |
489 | 3368 | 3368.0 | 76.99 | 77.0 | Tolerance, danger, and the extended family. | P Matzinger | Annu Rev Immunol | 1994 | 8011301 | No |
490 | 3368 | 3368.0 | 104.71 | 104.7 | Psychometric properties of the strengths and difficulties questionnaire. | R Goodman | J Am Acad Child Adolesc Psychiatry | 2001 | 11699809 | Yes |
491 | 6735 | 3367.5 | 133.82 | 66.9 | Statistical significance for genomewide studies. | John D Storey, Robert Tibshirani | Proc Natl Acad Sci U S A | 2003 | 12883005 | Yes |
492 | 10097 | 3365.7 | 365.58 | 121.9 | Cancer statistics, 2012. | Rebecca Siegel, Deepa Naishadham, Ahmedin Jemal | CA Cancer J Clin | 2012 | 22237781 | Yes |
493 | 3350 | 3350.0 | 68.44 | 68.4 | The scanning model for translation: an update. | M Kozak | J Cell Biol | 1989 | 2645293 | No |
494 | 6699 | 3349.5 | 184.65 | 92.3 | Velvet: algorithms for de novo short read assembly using de Bruijn graphs. | Daniel R Zerbino, Ewan Birney | Genome Res | 2008 | 18349386 | Yes |
495 | 3337 | 3337.0 | 81.57 | 81.6 | The basis of anisotropic water diffusion in the nervous system - a technical review. | Christian Beaulieu | NMR Biomed | 2002 | 12489094 | No |
496 | 3334 | 3334.0 | 123.18 | 123.2 | You want to measure coping but your protocol's too long: consider the brief COPE. | C S Carver | Int J Behav Med | 1997 | 16250744 | Yes |
497 | 3331 | 3331.0 | 68.11 | 68.1 | Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs. | M Kozak | Nucleic Acids Res | 1984 | 6694911 | Yes |
498 | 3330 | 3330.0 | 149.34 | 149.3 | The quality of care. How can it be assessed? | A Donabedian | JAMA | 1988 | 3045356 | No |
499 | 6643 | 3321.5 | 127.25 | 63.6 | The ubiquitin system. | A Hershko, A Ciechanover | Annu Rev Biochem | 1998 | 9759494 | No |
500 | 6637 | 3318.5 | 157.29 | 78.6 | Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. | C Tuerk, L Gold | Science | 1990 | 2200121 | Yes |
501 | 3318 | 3318.0 | 83.81 | 83.8 | Gene regulation by steroid hormones. | M Beato | Cell | 1989 | 2644044 | No |
502 | 6634 | 3317.0 | 141.93 | 71.0 | Angiogenesis in cancer and other diseases. | P Carmeliet, R K Jain | Nature | 2000 | 11001068 | No |
503 | 3306 | 3306.0 | 104.34 | 104.3 | Equilibrium Ultracentrifugation Of Dilute Solutions. | D A Yphantis | Biochemistry | 1964 | 14155091 | Yes |
504 | 3298 | 3298.0 | 79.91 | 79.9 | Wound healing--aiming for perfect skin regeneration. | P Martin | Science | 1997 | 9082989 | No |
505 | 3270 | 3270.0 | 88.81 | 88.8 | Hay fever, hygiene, and household size. | D P Strachan | BMJ | 1989 | 2513902 | Yes |
506 | 13075 | 3268.8 | 302.27 | 75.6 | Improved methods for building protein models in electron density maps and the location of errors in these models. | T A Jones, J Y Zou, S W Cowan, M Kjeldgaard | Acta Crystallogr A | 1991 | 2025413 | Yes |
507 | 6528 | 3264.0 | 204.26 | 102.1 | Human malaria parasites in continuous culture. | W Trager, J B Jensen | Science | 1976 | 781840 | Yes |
508 | 3263 | 3263.0 | 86.97 | 87.0 | ABC transporters: from microorganisms to man. | C F Higgins | Annu Rev Cell Biol | 1992 | 1282354 | No |
509 | 3263 | 3263.0 | 104.47 | 104.5 | No adjustments are needed for multiple comparisons. | K J Rothman | Epidemiology | 1990 | 2081237 | Yes |
510 | 3262 | 3262.0 | 64.09 | 64.1 | The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. | Isaiah J Fidler | Nat Rev Cancer | 2003 | 12778135 | No |
511 | 3254 | 3254.0 | 60.08 | 60.1 | Cell signaling by receptor tyrosine kinases. | J Schlessinger | Cell | 2000 | 11057895 | No |
512 | 3252 | 3252.0 | 93.37 | 93.4 | Inositol trisphosphate and diacylglycerol: two interacting second messengers. | M J Berridge | Annu Rev Biochem | 1987 | 3304132 | No |
513 | 3242 | 3242.0 | 66.71 | 66.7 | Alzheimer's disease is a synaptic failure. | Dennis J Selkoe | Science | 2002 | 12399581 | No |
514 | 3237 | 3237.0 | 76.59 | 76.6 | Photoelectrochemical cells. | M Grätzel | Nature | 2001 | 11713540 | Yes |
515 | 3235 | 3235.0 | 69.78 | 69.8 | Activators and target genes of Rel/NF-kappaB transcription factors. | H L Pahl | Oncogene | 1999 | 10602461 | No |
516 | 3233 | 3233.0 | 63.88 | 63.9 | STATs and gene regulation. | J E Darnell | Science | 1997 | 9287210 | No |
517 | 16147 | 3229.4 | 1177.1 | 235.4 | MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms. | Sudhir Kumar, Glen Stecher, Michael Li, Christina Knyaz, Koichiro Tamura | Mol Biol Evol | 2018 | 29722887 | Yes |
518 | 6452 | 3226.0 | 218.68 | 109.3 | Management of hepatocellular carcinoma: an update. | Jordi Bruix, Morris Sherman | Hepatology | 2011 | 21374666 | No |
519 | 3215 | 3215.0 | 95.79 | 95.8 | adegenet: a R package for the multivariate analysis of genetic markers. | Thibaut Jombart | Bioinformatics | 2008 | 18397895 | Yes |
520 | 3210 | 3210.0 | 79.43 | 79.4 | The transforming growth factor-beta family. | J Massagué | Annu Rev Cell Biol | 1990 | 2177343 | No |
521 | 3208 | 3208.0 | 73.29 | 73.3 | Mitochondrial formation of reactive oxygen species. | Julio F Turrens | J Physiol | 2003 | 14561818 | No |
522 | 3206 | 3206.0 | 111.61 | 111.6 | Transformed up-down methods in psychoacoustics. | H Levitt | J Acoust Soc Am | 1971 | 5541744 | Yes |
523 | 3200 | 3200.0 | 65.57 | 65.6 | CpG-rich islands and the function of DNA methylation. | A P Bird | Nature | 1986 | 2423876 | No |
524 | 6394 | 3197.0 | 199.82 | 99.9 | Superoxide dismutase: improved assays and an assay applicable to acrylamide gels. | C Beauchamp, I Fridovich | Anal Biochem | 1971 | 4943714 | Yes |
525 | 6382 | 3191.0 | 174.71 | 87.4 | Projections of global mortality and burden of disease from 2002 to 2030. | Colin D Mathers, Dejan Loncar | PLoS Med | 2006 | 17132052 | Yes |
526 | 3186 | 3186.0 | 96.65 | 96.7 | Development of a classification system for periodontal diseases and conditions. | G C Armitage | Ann Periodontol | 1999 | 10863370 | No |
527 | 3184 | 3184.0 | 66.73 | 66.7 | Protein folding and misfolding. | Christopher M Dobson | Nature | 2003 | 14685248 | No |
528 | 3172 | 3172.0 | 101.99 | 102.0 | Essential oils: their antibacterial properties and potential applications in foods--a review. | Sara Burt | Int J Food Microbiol | 2004 | 15246235 | No |
529 | 3162 | 3162.0 | 66.92 | 66.9 | Cardiac excitation-contraction coupling. | Donald M Bers | Nature | 2002 | 11805843 | No |
530 | 6324 | 3162.0 | 200.06 | 100.0 | Complex network measures of brain connectivity: uses and interpretations. | Mikail Rubinov, Olaf Sporns | Neuroimage | 2010 | 19819337 | Yes |
531 | 6307 | 3153.5 | 197.49 | 98.7 | The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. | Stephen B Edge, Carolyn C Compton | Ann Surg Oncol | 2010 | 20180029 | No |
532 | 3136 | 3136.0 | 73.89 | 73.9 | WHAT IF: a molecular modeling and drug design program. | G Vriend | J Mol Graph | 1990 | 2268628 | Yes |
533 | 3136 | 3136.0 | 0.0 | 0.0 | Diffusion-in-gel methods for immunological analysis. | O Ouchterlony | Prog Allergy | 1958 | 13578996 | Yes |
534 | 6258 | 3129.0 | 132.56 | 66.3 | Toll-like receptor signalling. | Shizuo Akira, Kiyoshi Takeda | Nat Rev Immunol | 2004 | 15229469 | No |
535 | 3128 | 3128.0 | 66.3 | 66.3 | Mechanisms of angiogenesis and arteriogenesis. | P Carmeliet | Nat Med | 2000 | 10742145 | No |
536 | 3123 | 3123.0 | 27.21 | 27.2 | Gene action in the X-chromosome of the mouse (Mus musculus L.). | M F Lyon | Nature | 1961 | 13764598 | Yes |
537 | 3121 | 3121.0 | 96.27 | 96.3 | Expert committee recommendations regarding the prevention, assessment, and treatment of child and adolescent overweight and obesity: summary report. | Sarah E Barlow | Pediatrics | 2007 | 18055651 | Yes |
538 | 3120 | 3120.0 | 66.02 | 66.0 | Angiogenesis in health and disease. | Peter Carmeliet | Nat Med | 2003 | 12778163 | No |
539 | 3118 | 3118.0 | 89.47 | 89.5 | Statistical tests of neutrality of mutations against population growth, hitchhiking and background selection. | Y X Fu | Genetics | 1997 | 9335623 | Yes |
540 | 6204 | 3102.0 | 100.92 | 50.5 | Pain mechanisms: a new theory. | R Melzack, P D Wall | Science | 1965 | 5320816 | No |
541 | 6203 | 3101.5 | 203.95 | 102.0 | Measuring agreement in method comparison studies. | J M Bland, D G Altman | Stat Methods Med Res | 1999 | 10501650 | No |
542 | 9296 | 3098.7 | 312.89 | 104.3 | Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. | R M Palmer, A G Ferrige, S Moncada | Nature | 1987 | 3495737 | Yes |
543 | 6196 | 3098.0 | 149.59 | 74.8 | Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. | Weizhong Li, Adam Godzik | Bioinformatics | 2006 | 16731699 | Yes |
544 | 6194 | 3097.0 | 150.99 | 75.5 | In vitro selection of RNA molecules that bind specific ligands. | A D Ellington, J W Szostak | Nature | 1990 | 1697402 | Yes |
545 | 3096 | 3096.0 | 119.65 | 119.7 | Half a century of research on the Stroop effect: an integrative review. | C M MacLeod | Psychol Bull | 1991 | 2034749 | No |
546 | 3095 | 3095.0 | 54.56 | 54.6 | Automated electron microscope tomography using robust prediction of specimen movements. | David N Mastronarde | J Struct Biol | 2005 | 16182563 | Yes |
547 | 9278 | 3092.7 | 194.04 | 64.7 | Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. | Benjamin P Lewis, Christopher B Burge, David P Bartel | Cell | 2005 | 15652477 | Yes |
548 | 3089 | 3089.0 | 85.75 | 85.8 | Rapid isolation of antigens from cells with a staphylococcal protein A-antibody adsorbent: parameters of the interaction of antibody-antigen complexes with protein A. | S W Kessler | J Immunol | 1975 | 1102604 | Yes |
549 | 12356 | 3089.0 | 469.94 | 117.5 | APACHE II: a severity of disease classification system. | W A Knaus, E A Draper, D P Wagner, J E Zimmerman | Crit Care Med | 1985 | 3928249 | Yes |
550 | 6168 | 3084.0 | 181.29 | 90.6 | Complex brain networks: graph theoretical analysis of structural and functional systems. | Ed Bullmore, Olaf Sporns | Nat Rev Neurosci | 2009 | 19190637 | No |
551 | 6165 | 3082.5 | 150.16 | 75.1 | Exploring the full spectrum of macrophage activation. | David M Mosser, Justin P Edwards | Nat Rev Immunol | 2008 | 19029990 | No |
552 | 6157 | 3078.5 | 155.7 | 77.8 | Voxel-based morphometry--the methods. | J Ashburner, K J Friston | Neuroimage | 2000 | 10860804 | No |
553 | 3075 | 3075.0 | 75.97 | 76.0 | Recent advances with liposomes as pharmaceutical carriers. | Vladimir P Torchilin | Nat Rev Drug Discov | 2005 | 15688077 | No |
554 | 6149 | 3074.5 | 53.53 | 26.8 | The serial cultivation of human diploid cell strains. | L Hayflick, P S Moorhead | Exp Cell Res | 1961 | 13905658 | Yes |
555 | 3069 | 3069.0 | 72.73 | 72.7 | Obesity as a medical problem. | P G Kopelman | Nature | 2000 | 10766250 | No |
556 | 9205 | 3068.3 | 259.68 | 86.6 | Detecting the number of clusters of individuals using the software STRUCTURE: a simulation study. | G Evanno, S Regnaut, J Goudet | Mol Ecol | 2005 | 15969739 | Yes |
557 | 6135 | 3067.5 | 136.54 | 68.3 | MicroRNA signatures in human cancers. | George A Calin, Carlo M Croce | Nat Rev Cancer | 2006 | 17060945 | No |
558 | 3060 | 3060.0 | 89.48 | 89.5 | Hepatocellular carcinoma. | Hashem B El-Serag | N Engl J Med | 2011 | 21992124 | No |
559 | 6103 | 3051.5 | 108.22 | 54.1 | The language of covalent histone modifications. | B D Strahl, C D Allis | Nature | 2000 | 10638745 | Yes |
560 | 3051 | 3051.0 | 107.67 | 107.7 | The Danish Civil Registration System. | Carsten Bøcker Pedersen | Scand J Public Health | 2011 | 21775345 | Yes |
561 | 3046 | 3046.0 | 122.93 | 122.9 | Adolescence-limited and life-course-persistent antisocial behavior: a developmental taxonomy. | T E Moffitt | Psychol Rev | 1993 | 8255953 | No |
562 | 3044 | 3044.0 | 70.55 | 70.5 | Cadherin cell adhesion receptors as a morphogenetic regulator. | M Takeichi | Science | 1991 | 2006419 | No |
563 | 3043 | 3043.0 | 104.76 | 104.8 | The processing-speed theory of adult age differences in cognition. | T A Salthouse | Psychol Rev | 1996 | 8759042 | No |
564 | 6072 | 3036.0 | 188.62 | 94.3 | Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees. | K Tamura, M Nei | Mol Biol Evol | 1993 | 8336541 | Yes |
565 | 3033 | 3033.0 | 108.93 | 108.9 | Quantifying test-retest reliability using the intraclass correlation coefficient and the SEM. | Joseph P Weir | J Strength Cond Res | 2005 | 15705040 | No |
566 | 6064 | 3032.0 | 162.03 | 81.0 | The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. | Taro Kawai, Shizuo Akira | Nat Immunol | 2010 | 20404851 | No |
567 | 6047 | 3023.5 | 178.67 | 89.3 | Electrochemical photolysis of water at a semiconductor electrode. | A Fujishima, K Honda | Nature | 1972 | 12635268 | Yes |
568 | 3020 | 3020.0 | 76.2 | 76.2 | Cellular and molecular mechanisms of fibrosis. | T A Wynn | J Pathol | 2008 | 18161745 | No |
569 | 6030 | 3015.0 | 0.0 | 0.0 | A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. | S Reitman, S Frankel | Am J Clin Pathol | 1957 | 13458125 | Yes |
570 | 3015 | 3015.0 | 107.47 | 107.5 | A Rapid Permethylation Of Glycolipid, And Polysaccharide Catalyzed By Methylsulfinyl Carbanion In Dimethyl Sulfoxide. | S Hakomori | J Biochem | 1964 | 14135466 | Yes |
571 | 6028 | 3014.0 | 180.03 | 90.0 | mTOR signaling in growth control and disease. | Mathieu Laplante, David M Sabatini | Cell | 2012 | 22500797 | No |
572 | 3012 | 3012.0 | 0.0 | 0.0 | A study of fixation for electron microscopy. | G E Palade | J Exp Med | 1952 | 14927794 | Yes |
573 | 9034 | 3011.3 | 178.72 | 59.6 | Significance analysis of microarrays applied to the ionizing radiation response. | V G Tusher, R Tibshirani, G Chu | Proc Natl Acad Sci U S A | 2001 | 11309499 | Yes |
574 | 3010 | 3010.0 | 64.75 | 64.8 | TGFbeta in Cancer. | Joan Massagué | Cell | 2008 | 18662538 | No |
575 | 2993 | 2993.0 | 95.05 | 95.0 | An empirical correction for absorption anisotropy. | R H Blessing | Acta Crystallogr A | 1995 | 7702794 | Yes |
576 | 2990 | 2990.0 | 102.12 | 102.1 | Measurement of pain. | E C Huskisson | Lancet | 1974 | 4139420 | Yes |
577 | 11940 | 2985.0 | 282.87 | 70.7 | Haploview: analysis and visualization of LD and haplotype maps. | J C Barrett, B Fry, J Maller, M J Daly | Bioinformatics | 2005 | 15297300 | Yes |
578 | 2984 | 2984.0 | 72.45 | 72.5 | The resurgence of platinum-based cancer chemotherapy. | Lloyd Kelland | Nat Rev Cancer | 2007 | 17625587 | No |
579 | 2983 | 2983.0 | 55.89 | 55.9 | Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and lamm equation modeling. | P Schuck | Biophys J | 2000 | 10692345 | Yes |
580 | 2980 | 2980.0 | 69.01 | 69.0 | Chemokines--chemotactic cytokines that mediate inflammation. | A D Luster | N Engl J Med | 1998 | 9459648 | No |
581 | 5959 | 2979.5 | 249.89 | 124.9 | Assessment of outcome after severe brain damage. | B Jennett, M Bond | Lancet | 1975 | 46957 | Yes |
582 | 5957 | 2978.5 | 141.2 | 70.6 | Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. | T C Chou, P Talalay | Adv Enzyme Regul | 1984 | 6382953 | Yes |
583 | 2978 | 2978.0 | 52.78 | 52.8 | The gel-filtration behaviour of proteins related to their molecular weights over a wide range. | P Andrews | Biochem J | 1965 | 5862401 | Yes |
584 | 2977 | 2977.0 | 0.0 | 0.0 | Catheter replacement of the needle in percutaneous arteriography; a new technique. | S I Seldinger | Acta radiol | 1953 | 13057644 | Yes |
585 | 5949 | 2974.5 | 125.36 | 62.7 | Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. | D B Smith, K S Johnson | Gene | 1988 | 3047011 | Yes |
586 | 2972 | 2972.0 | 134.57 | 134.6 | The short-form McGill Pain Questionnaire. | Ronald Melzack | Pain | 1987 | 3670870 | Yes |
587 | 5941 | 2970.5 | 134.38 | 67.2 | Oxidants, oxidative stress and the biology of ageing. | T Finkel, N J Holbrook | Nature | 2000 | 11089981 | No |
588 | 8897 | 2965.7 | 207.35 | 69.1 | TopHat: discovering splice junctions with RNA-Seq. | Cole Trapnell, Lior Pachter, Steven L Salzberg | Bioinformatics | 2009 | 19289445 | Yes |
589 | 23720 | 2965.0 | 515.86 | 64.5 | The Protein Data Bank. | H M Berman, J Westbrook, Z Feng, G Gilliland, T N Bhat, H Weissig, I N Shindyalov, P E Bourne | Nucleic Acids Res | 2000 | 10592235 | Yes |
590 | 26681 | 2964.6 | 574.19 | 63.8 | Cytoscape: a software environment for integrated models of biomolecular interaction networks. | Paul Shannon, Andrew Markiel, Owen Ozier, Nitin S Baliga, Jonathan T Wang, Daniel Ramage, Nada Amin, Benno Schwikowski, Trey Ideker | Genome Res | 2003 | 14597658 | Yes |
591 | 2962 | 2962.0 | 58.85 | 58.9 | Toll-like receptors and innate immunity. | R Medzhitov | Nat Rev Immunol | 2001 | 11905821 | No |
592 | 2957 | 2957.0 | 101.67 | 101.7 | What is value in health care? | Michael E Porter | N Engl J Med | 2010 | 21142528 | Yes |
593 | 2956 | 2956.0 | 78.18 | 78.2 | Accurate Coulomb-fitting basis sets for H to Rn. | Florian Weigend | Phys Chem Chem Phys | 2006 | 16633586 | Yes |
594 | 2953 | 2953.0 | 90.88 | 90.9 | Matrix metalloproteinases and their inhibitors in connective tissue remodeling. | J F Woessner | FASEB J | 1991 | 1850705 | No |
595 | 2950 | 2950.0 | 54.76 | 54.8 | RNA interference. | Gregory J Hannon | Nature | 2002 | 12110901 | No |
596 | 8843 | 2947.7 | 242.55 | 80.9 | Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. | Y Gavrieli, Y Sherman, S A Ben-Sasson | J Cell Biol | 1992 | 1400587 | Yes |
597 | 2946 | 2946.0 | 80.23 | 80.2 | The nuclear factor NF-kappaB pathway in inflammation. | Toby Lawrence | Cold Spring Harb Perspect Biol | 2009 | 20457564 | No |
598 | 5880 | 2940.0 | 184.84 | 92.4 | Tissue engineering. | R Langer, J P Vacanti | Science | 1993 | 8493529 | No |
599 | 5879 | 2939.5 | 124.82 | 62.4 | Emergence of scaling in random networks | A L Barabasi, R Albert | Science | 1999 | 10521342 | Yes |
600 | 2936 | 2936.0 | 73.12 | 73.1 | Optimal two-stage designs for phase II clinical trials. | R Simon | Control Clin Trials | 1989 | 2702835 | Yes |
601 | 8776 | 2925.3 | 286.46 | 95.5 | Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. | R A Deyo, D C Cherkin, M A Ciol | J Clin Epidemiol | 1992 | 1607900 | Yes |
602 | 8753 | 2917.7 | 215.92 | 72.0 | ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. | Kai Wang, Mingyao Li, Hakon Hakonarson | Nucleic Acids Res | 2010 | 20601685 | Yes |
603 | 2909 | 2909.0 | 88.6 | 88.6 | Estimation of metabolite concentrations from localized in vivo proton NMR spectra. | S W Provencher | Magn Reson Med | 1993 | 8139448 | Yes |
604 | 5811 | 2905.5 | 173.89 | 86.9 | The fluid mosaic model of the structure of cell membranes. | S J Singer, G L Nicolson | Science | 1972 | 4333397 | Yes |
605 | 5808 | 2904.0 | 162.61 | 81.3 | Inositol trisphosphate, a novel second messenger in cellular signal transduction. | M J Berridge, R F Irvine | Nature | 1984 | 6095092 | No |
606 | 11597 | 2899.2 | 425.52 | 106.4 | Statistical power analyses using G*Power 3.1: tests for correlation and regression analyses. | Franz Faul, Edgar Erdfelder, Axel Buchner, Albert-Georg Lang | Behav Res Methods | 2009 | 19897823 | Yes |
607 | 2899 | 2899.0 | 0.0 | 0.0 | The genetical structure of populations. | S Wright | Ann Eugen | 1951 | 24540312 | Yes |
608 | 2897 | 2897.0 | 60.16 | 60.2 | Principles of CDK regulation. | D O Morgan | Nature | 1995 | 7877684 | No |
609 | 8682 | 2894.0 | 0.0 | 0.0 | The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. | R J Havel, H A Eder, J H Bragdon | J Clin Invest | 1955 | 13252080 | Yes |
610 | 2894 | 2894.0 | 65.29 | 65.3 | Autophagy: process and function. | Noboru Mizushima | Genes Dev | 2007 | 18006683 | No |
611 | 8681 | 2893.7 | 164.7 | 54.9 | Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. | Ron Edgar, Michael Domrachev, Alex E Lash | Nucleic Acids Res | 2002 | 11752295 | Yes |
612 | 5784 | 2892.0 | 252.47 | 126.2 | GenAlEx 6.5: genetic analysis in Excel. Population genetic software for teaching and research--an update. | Rod Peakall, Peter E Smouse | Bioinformatics | 2012 | 22820204 | Yes |
613 | 5781 | 2890.5 | 214.56 | 107.3 | The structure of negative emotional states: comparison of the Depression Anxiety Stress Scales (DASS) with the Beck Depression and Anxiety Inventories. | P F Lovibond, S H Lovibond | Behav Res Ther | 1995 | 7726811 | Yes |
614 | 2890 | 2890.0 | 70.24 | 70.2 | Phase separation of integral membrane proteins in Triton X-114 solution. | C Bordier | J Biol Chem | 1981 | 6257680 | Yes |
615 | 2889 | 2889.0 | 83.57 | 83.6 | Efficient methods to compute genomic predictions. | P M VanRaden | J Dairy Sci | 2008 | 18946147 | Yes |
616 | 8644 | 2881.3 | 198.52 | 66.2 | The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. | R C Lee, R L Feinbaum, V Ambros | Cell | 1993 | 8252621 | Yes |
617 | 2880 | 2880.0 | 86.28 | 86.3 | Implications of normal brain development for the pathogenesis of schizophrenia. | D R Weinberger | Arch Gen Psychiatry | 1987 | 3606332 | Yes |
618 | 5758 | 2879.0 | 182.4 | 91.2 | Self-determination theory and the facilitation of intrinsic motivation, social development, and well-being. | R M Ryan, E L Deci | Am Psychol | 2000 | 11392867 | Yes |
619 | 2878 | 2878.0 | 68.48 | 68.5 | Structure and function of telomeres. | E H Blackburn | Nature | 1991 | 1708110 | No |
620 | 2874 | 2874.0 | 51.22 | 51.2 | One-step gene disruption in yeast. | R J Rothstein | Methods Enzymol | 1983 | 6310324 | Yes |
621 | 2873 | 2873.0 | 61.79 | 61.8 | Inflammatory bowel disease. | Daniel K Podolsky | N Engl J Med | 2002 | 12167685 | No |
622 | 2869 | 2869.0 | 43.55 | 43.5 | Towards a network theory of the immune system. | N K Jerne | Ann Immunol (Paris) | 1974 | 4142565 | No |
623 | 2869 | 2869.0 | 29.35 | 29.4 | Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism. | P Mitchell | Nature | 1961 | 13771349 | Yes |
624 | 5738 | 2869.0 | 126.91 | 63.5 | Oncomirs - microRNAs with a role in cancer. | Aurora Esquela-Kerscher, Frank J Slack | Nat Rev Cancer | 2006 | 16557279 | No |
625 | 2868 | 2868.0 | 100.29 | 100.3 | Measures of reliability in sports medicine and science. | W G Hopkins | Sports Med | 2000 | 10907753 | Yes |
626 | 2867 | 2867.0 | 95.62 | 95.6 | Role of oxidative stress in development of complications in diabetes. | J W Baynes | Diabetes | 1991 | 2010041 | No |
627 | 5728 | 2864.0 | 120.95 | 60.5 | Inflammation and cancer: back to Virchow? | F Balkwill, A Mantovani | Lancet | 2001 | 11229684 | No |
628 | 2864 | 2864.0 | 50.43 | 50.4 | A Generalized Wilcoxon Test For Comparing Arbitrarily Singly-Censored Samples. | E A Gehan | Biometrika | 1965 | 14341275 | Yes |
629 | 2860 | 2860.0 | 0.0 | 0.0 | Phosphorus compounds in animal tissues; extraction and estimation of desoxypentose nucleic acid and of pentose nucleic acid. | W C Schneider | J Biol Chem | 1945 | 21005736 | Yes |
630 | 2857 | 2857.0 | 52.89 | 52.9 | Genome maintenance mechanisms for preventing cancer. | J H Hoeijmakers | Nature | 2001 | 11357144 | No |
631 | 2857 | 2857.0 | 0.0 | 0.0 | A study of the adrenotropic receptors. | R P Ahlquist | Am J Physiol | 1948 | 18882199 | Yes |
632 | 2851 | 2851.0 | 67.27 | 67.3 | MapChart: software for the graphical presentation of linkage maps and QTLs. | R E Voorrips | J Hered | 2002 | 12011185 | Yes |
633 | 8552 | 2850.7 | 255.78 | 85.3 | Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane. | G Fairbanks, T L Steck, D F Wallach | Biochemistry | 1971 | 4326772 | Yes |
634 | 5689 | 2844.5 | 144.91 | 72.5 | Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain. | J Glowinski, L L Iversen | J Neurochem | 1966 | 5950056 | Yes |
635 | 2842 | 2842.0 | 0.0 | 0.0 | Notes on sugar determination. | M Smogyi | J Biol Chem | 1952 | 14938350 | Yes |
636 | 5683 | 2841.5 | 247.12 | 123.6 | Revised methods for the Salmonella mutagenicity test. | D M Maron, B N Ames | Mutat Res | 1983 | 6341825 | Yes |
637 | 2840 | 2840.0 | 46.37 | 46.4 | A Rationale And Test For The Number Of Factors In Factor Analysis. | J L Horn | Psychometrika | 1965 | 14306381 | Yes |
638 | 2839 | 2839.0 | 93.82 | 93.8 | Some studies of the protein-binding of steroids and their application to the routine micro and ultramicro measurement of various steroids in body fluids by competitive protein-binding radioassay. | B E Murphy | J Clin Endocrinol Metab | 1967 | 4291524 | Yes |
639 | 5674 | 2837.0 | 149.11 | 74.6 | Pattern recognition receptors and inflammation. | Osamu Takeuchi, Shizuo Akira | Cell | 2010 | 20303872 | No |
640 | 2833 | 2833.0 | 54.81 | 54.8 | A gene complex controlling segmentation in Drosophila. | E B Lewis | Nature | 1978 | 103000 | Yes |
641 | 2831 | 2831.0 | 64.24 | 64.2 | Calcium signaling. | David E Clapham | Cell | 2007 | 18083096 | No |
642 | 11304 | 2826.0 | 333.76 | 83.4 | Naive Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy. | Qiong Wang, George M Garrity, James M Tiedje, James R Cole | Appl Environ Microbiol | 2007 | 17586664 | Yes |
643 | 5648 | 2824.0 | 149.37 | 74.7 | Unified segmentation. | John Ashburner, Karl J Friston | Neuroimage | 2005 | 15955494 | Yes |
644 | 8460 | 2820.0 | 431.46 | 143.8 | Methods for dietary fiber, neutral detergent fiber, and nonstarch polysaccharides in relation to animal nutrition. | P J Van Soest, J B Robertson, B A Lewis | J Dairy Sci | 1991 | 1660498 | No |
645 | 2819 | 2819.0 | 60.82 | 60.8 | Nuclear factor-kappaB in cancer development and progression. | Michael Karin | Nature | 2006 | 16724054 | No |
646 | 2817 | 2817.0 | 55.62 | 55.6 | Interleukin-12 and the regulation of innate resistance and adaptive immunity. | Giorgio Trinchieri | Nat Rev Immunol | 2003 | 12563297 | No |
647 | 2813 | 2813.0 | 55.73 | 55.7 | Papillomaviruses and cancer: from basic studies to clinical application. | Harald zur Hausen | Nat Rev Cancer | 2002 | 12044010 | No |
648 | 2812 | 2812.0 | 71.14 | 71.1 | Analysis of gene diversity in subdivided populations. | M Nei | Proc Natl Acad Sci U S A | 1973 | 4519626 | Yes |
649 | 2811 | 2811.0 | 65.8 | 65.8 | Modularity and community structure in networks. | M E J Newman | Proc Natl Acad Sci U S A | 2006 | 16723398 | Yes |
650 | 2808 | 2808.0 | 53.62 | 53.6 | Elastic properties of lipid bilayers: theory and possible experiments. | W Helfrich | Z Naturforsch C | 1973 | 4273690 | Yes |
651 | 5602 | 2801.0 | 152.33 | 76.2 | The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers. | J Vieira, J Messing | Gene | 1982 | 6295879 | Yes |
652 | 5597 | 2798.5 | 126.77 | 63.4 | Caspases: enemies within. | N A Thornberry, Y Lazebnik | Science | 1998 | 9721091 | No |
653 | 2798 | 2798.0 | 84.88 | 84.9 | Primate models of movement disorders of basal ganglia origin. | M R DeLong | Trends Neurosci | 1990 | 1695404 | No |
654 | 2798 | 2798.0 | 93.38 | 93.4 | Stereotaxic mapping of the monoamine pathways in the rat brain. | U Ungerstedt | Acta Physiol Scand Suppl | 1971 | 4109331 | Yes |
655 | 2795 | 2795.0 | 74.28 | 74.3 | Separation of leukocytes from blood and bone marrow. Introduction. | A Böyum | Scand J Clin Lab Invest Suppl | 1968 | 5707208 | Yes |
656 | 5584 | 2792.0 | 112.49 | 56.2 | Establishment in culture of pluripotential cells from mouse embryos. | M J Evans, M H Kaufman | Nature | 1981 | 7242681 | Yes |
657 | 5578 | 2789.0 | 77.79 | 38.9 | A method for determining the sedimentation behavior of enzymes: application to protein mixtures. | R G Martin, B N Ames | J Biol Chem | 1961 | 13767412 | Yes |
658 | 2788 | 2788.0 | 65.27 | 65.3 | Molecular chaperones in cellular protein folding. | F U Hartl | Nature | 1996 | 8637592 | No |
659 | 11141 | 2785.2 | 297.51 | 74.4 | Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. | P W Rigby, M Dieckmann, C Rhodes, P Berg | J Mol Biol | 1977 | 881736 | Yes |
660 | 5570 | 2785.0 | 173.04 | 86.5 | Computed tomography--an increasing source of radiation exposure. | David J Brenner, Eric J Hall | N Engl J Med | 2007 | 18046031 | No |
661 | 2784 | 2784.0 | 47.76 | 47.8 | Mechanisms underlying ubiquitination. | C M Pickart | Annu Rev Biochem | 2001 | 11395416 | No |
662 | 5566 | 2783.0 | 192.35 | 96.2 | A method of comparing the areas under receiver operating characteristic curves derived from the same cases. | J A Hanley, B J McNeil | Radiology | 1983 | 6878708 | Yes |
663 | 2782 | 2782.0 | 0.0 | 0.0 | Efficient trace-labelling of proteins with iodine. | A S McFARLANE | Nature | 1958 | 13566175 | Yes |
664 | 2780 | 2780.0 | 115.84 | 115.8 | Colorimetric assay of catalase. | A K Sinha | Anal Biochem | 1972 | 4556490 | Yes |
665 | 5546 | 2773.0 | 133.16 | 66.6 | Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. | S Marklund, G Marklund | Eur J Biochem | 1974 | 4215654 | Yes |
666 | 2773 | 2773.0 | 61.9 | 61.9 | Salt and drought stress signal transduction in plants. | Jian-Kang Zhu | Annu Rev Plant Biol | 2002 | 12221975 | No |
667 | 11083 | 2770.8 | 341.24 | 85.3 | Cancer statistics, 2010. | Ahmedin Jemal, Rebecca Siegel, Jiaquan Xu, Elizabeth Ward | CA Cancer J Clin | 2010 | 20610543 | Yes |
668 | 5541 | 2770.5 | 173.87 | 86.9 | Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. | J Sedlak, R H Lindsay | Anal Biochem | 1968 | 4973948 | Yes |
669 | 2765 | 2765.0 | 0.0 | 0.0 | Quantitative estimation of sialic acids. II. A colorimetric resorcinol-hydrochloric acid method. | L Svennerholm | Biochim Biophys Acta | 1957 | 13436486 | Yes |
670 | 2764 | 2764.0 | 124.98 | 125.0 | Detecting alcoholism. The CAGE questionnaire. | J A Ewing | JAMA | 1984 | 6471323 | Yes |
671 | 8284 | 2761.3 | 189.41 | 63.1 | Pathogen recognition and innate immunity. | Shizuo Akira, Satoshi Uematsu, Osamu Takeuchi | Cell | 2006 | 16497588 | No |
672 | 2760 | 2760.0 | 104.65 | 104.7 | A simple technique for demonstrating centromeric heterochromatin. | A T Sumner | Exp Cell Res | 1972 | 4117921 | Yes |
673 | 30352 | 2759.3 | 632.58 | 57.5 | Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. | Aravind Subramanian, Pablo Tamayo, Vamsi K Mootha, Sayan Mukherjee, Benjamin L Ebert, Michael A Gillette, Amanda Paulovich, Scott L Pomeroy, Todd R Golub, Eric S Lander, Jill P Mesirov | Proc Natl Acad Sci U S A | 2005 | 16199517 | Yes |
674 | 5517 | 2758.5 | 109.61 | 54.8 | Innate immune recognition. | Charles A Janeway, Ruslan Medzhitov | Annu Rev Immunol | 2002 | 11861602 | No |
675 | 2756 | 2756.0 | 66.49 | 66.5 | Cell death during development of the nervous system. | R W Oppenheim | Annu Rev Neurosci | 1991 | 2031577 | No |
676 | 2755 | 2755.0 | 79.61 | 79.6 | Improving the quality of Web surveys: the Checklist for Reporting Results of Internet E-Surveys (CHERRIES). | Gunther Eysenbach | J Med Internet Res | 2004 | 15471760 | No |
677 | 5506 | 2753.0 | 133.63 | 66.8 | Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. | D Hanahan, J Folkman | Cell | 1996 | 8756718 | No |
678 | 2752 | 2752.0 | 112.47 | 112.5 | Microplastics in the marine environment. | Anthony L Andrady | Mar Pollut Bull | 2011 | 21742351 | No |
679 | 5501 | 2750.5 | 129.99 | 65.0 | Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. | F W Studier, B A Moffatt | J Mol Biol | 1986 | 3537305 | Yes |
680 | 5490 | 2745.0 | 85.2 | 42.6 | A modified uronic acid carbazole reaction. | T Bitter, H M Muir | Anal Biochem | 1962 | 13971270 | Yes |
681 | 2744 | 2744.0 | 68.33 | 68.3 | Models for the specific adhesion of cells to cells. | G I Bell | Science | 1978 | 347575 | No |
682 | 2739 | 2739.0 | 103.42 | 103.4 | KDIGO clinical practice guidelines for acute kidney injury. | Arif Khwaja | Nephron Clin Pract | 2012 | 22890468 | No |
683 | 5468 | 2734.0 | 167.04 | 83.5 | Glutathione. | A Meister, M E Anderson | Annu Rev Biochem | 1983 | 6137189 | No |
684 | 5463 | 2731.5 | 197.61 | 98.8 | Longitudinal data analysis for discrete and continuous outcomes. | S L Zeger, K Y Liang | Biometrics | 1986 | 3719049 | Yes |
685 | 2729 | 2729.0 | 69.2 | 69.2 | The genetic legacy of the Quaternary ice ages. | G Hewitt | Nature | 2000 | 10879524 | No |
686 | 8177 | 2725.7 | 353.97 | 118.0 | Detection of postnatal depression. Development of the 10-item Edinburgh Postnatal Depression Scale. | J L Cox, J M Holden, R Sagovsky | Br J Psychiatry | 1987 | 3651732 | Yes |
687 | 2722 | 2722.0 | 53.12 | 53.1 | The danger model: a renewed sense of self. | Polly Matzinger | Science | 2002 | 11951032 | Yes |
688 | 2721 | 2721.0 | 70.26 | 70.3 | Predictive reward signal of dopamine neurons. | W Schultz | J Neurophysiol | 1998 | 9658025 | No |
689 | 5439 | 2719.5 | 150.84 | 75.4 | Adherence to medication. | Lars Osterberg, Terrence Blaschke | N Engl J Med | 2005 | 16079372 | No |
690 | 5435 | 2717.5 | 107.39 | 53.7 | High-efficiency transformation of mammalian cells by plasmid DNA. | C Chen, H Okayama | Mol Cell Biol | 1987 | 3670292 | Yes |
691 | 2717 | 2717.0 | 61.43 | 61.4 | Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. | S A Bustin | J Mol Endocrinol | 2000 | 11013345 | No |
692 | 2714 | 2714.0 | 68.58 | 68.6 | Dietary pattern analysis: a new direction in nutritional epidemiology. | Frank B Hu | Curr Opin Lipidol | 2002 | 11790957 | No |
693 | 8137 | 2712.3 | 174.83 | 58.3 | Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. | C M Gorman, L F Moffat, B H Howard | Mol Cell Biol | 1982 | 6960240 | Yes |
694 | 5422 | 2711.0 | 126.65 | 63.3 | Autophagy in the pathogenesis of disease. | Beth Levine, Guido Kroemer | Cell | 2008 | 18191218 | No |
695 | 2707 | 2707.0 | 58.59 | 58.6 | Bone resorption by osteoclasts. | S L Teitelbaum | Science | 2000 | 10968780 | No |
696 | 18936 | 2705.1 | 725.79 | 103.7 | limma powers differential expression analyses for RNA-sequencing and microarray studies. | Matthew E Ritchie, Belinda Phipson, Di Wu, Yifang Hu, Charity W Law, Wei Shi, Gordon K Smyth | Nucleic Acids Res | 2015 | 25605792 | Yes |
697 | 2705 | 2705.0 | 62.87 | 62.9 | Memory--a century of consolidation. | J L McGaugh | Science | 2000 | 10634773 | No |
698 | 2703 | 2703.0 | 103.09 | 103.1 | Role of nrf2 in oxidative stress and toxicity. | Qiang Ma | Annu Rev Pharmacol Toxicol | 2013 | 23294312 | No |
699 | 24299 | 2699.9 | 777.9 | 86.4 | STAR: ultrafast universal RNA-seq aligner. | Alexander Dobin, Carrie A Davis, Felix Schlesinger, Jorg Drenkow, Chris Zaleski, Sonali Jha, Philippe Batut, Mark Chaisson, Thomas R Gingeras | Bioinformatics | 2013 | 23104886 | Yes |
700 | 2697 | 2697.0 | 60.76 | 60.8 | Cell adhesion: the molecular basis of tissue architecture and morphogenesis. | B M Gumbiner | Cell | 1996 | 8608588 | No |
701 | 5392 | 2696.0 | 258.15 | 129.1 | Stress, social support, and the buffering hypothesis. | S Cohen, T A Wills | Psychol Bull | 1985 | 3901065 | No |
702 | 5388 | 2694.0 | 168.45 | 84.2 | Accurate and simple analytic representation of the electron-gas correlation energy. | J P Perdew, Y Wang | Phys Rev B Condens Matter | 1992 | 10001404 | Yes |
703 | 8082 | 2694.0 | 200.63 | 66.9 | MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment. | Sudhir Kumar, Koichiro Tamura, Masatoshi Nei | Brief Bioinform | 2004 | 15260895 | Yes |
704 | 5374 | 2687.0 | 154.01 | 77.0 | The Social Readjustment Rating Scale. | T H Holmes, R H Rahe | J Psychosom Res | 1967 | 6059863 | Yes |
705 | 10734 | 2683.5 | 227.84 | 57.0 | Cluster analysis and display of genome-wide expression patterns. | M B Eisen, P T Spellman, P O Brown, D Botstein | Proc Natl Acad Sci U S A | 1998 | 9843981 | Yes |
706 | 8040 | 2680.0 | 198.64 | 66.2 | Canonical sampling through velocity rescaling. | Giovanni Bussi, Davide Donadio, Michele Parrinello | J Chem Phys | 2007 | 17212484 | Yes |
707 | 2678 | 2678.0 | 75.74 | 75.7 | Parkinson's disease: clinical features and diagnosis. | J Jankovic | J Neurol Neurosurg Psychiatry | 2008 | 18344392 | No |
708 | 2675 | 2675.0 | 60.48 | 60.5 | Prostaglandins and leukotrienes: advances in eicosanoid biology. | C D Funk | Science | 2001 | 11729303 | No |
709 | 2668 | 2668.0 | 80.7 | 80.7 | SF-36 health survey update. | J E Ware | Spine (Phila Pa 1976) | 2000 | 11124729 | No |
710 | 10662 | 2665.5 | 314.77 | 78.7 | Establishing a standard definition for child overweight and obesity worldwide: international survey. | T J Cole, M C Bellizzi, K M Flegal, W H Dietz | BMJ | 2000 | 10797032 | Yes |
711 | 2660 | 2660.0 | 51.53 | 51.5 | Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. | Shimon Sakaguchi | Annu Rev Immunol | 2004 | 15032588 | No |
712 | 2657 | 2657.0 | 68.77 | 68.8 | Protein purification by affinity chromatography. Derivatizations of agarose and polyacrylamide beads. | P Cuatrecasas | J Biol Chem | 1970 | 5432796 | Yes |
713 | 2653 | 2653.0 | 70.28 | 70.3 | The magical number 4 in short-term memory: a reconsideration of mental storage capacity. | N Cowan | Behav Brain Sci | 2001 | 11515286 | Yes |
714 | 2653 | 2653.0 | 23.31 | 23.3 | Satellite cell of skeletal muscle fibers. | A Mauro | J Biophys Biochem Cytol | 1961 | 13768451 | Yes |
715 | 2651 | 2651.0 | 57.65 | 57.6 | On the number of segregating sites in genetical models without recombination. | G A Watterson | Theor Popul Biol | 1975 | 1145509 | Yes |
716 | 2648 | 2648.0 | 63.8 | 63.8 | T cell exhaustion. | E John Wherry | Nat Immunol | 2011 | 21739672 | No |
717 | 5278 | 2639.0 | 180.8 | 90.4 | The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions. | S H Downs, N Black | J Epidemiol Community Health | 1998 | 9764259 | Yes |
718 | 2638 | 2638.0 | 65.7 | 65.7 | The nerve growth factor 35 years later. | R Levi-Montalcini | Science | 1987 | 3306916 | No |
719 | 2637 | 2637.0 | 60.28 | 60.3 | Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface. | G P Smith | Science | 1985 | 4001944 | Yes |
720 | 2636 | 2636.0 | 81.78 | 81.8 | What are the functional consequences of neurocognitive deficits in schizophrenia? | M F Green | Am J Psychiatry | 1996 | 8610818 | No |
721 | 2633 | 2633.0 | 77.94 | 77.9 | The unfolded protein response: controlling cell fate decisions under ER stress and beyond. | Claudio Hetz | Nat Rev Mol Cell Biol | 2012 | 22251901 | No |
722 | 5262 | 2631.0 | 0.0 | 0.0 | Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid. | J D Watson, F H Crick | Nature | 1953 | 13054692 | Yes |
723 | 5261 | 2630.5 | 155.16 | 77.6 | Long-range corrected hybrid density functionals with damped atom-atom dispersion corrections. | Jeng-Da Chai, Martin Head-Gordon | Phys Chem Chem Phys | 2008 | 18989472 | Yes |
724 | 5254 | 2627.0 | 181.48 | 90.7 | Extracellular vesicles: exosomes, microvesicles, and friends. | Graça Raposo, Willem Stoorvogel | J Cell Biol | 2013 | 23420871 | No |
725 | 5248 | 2624.0 | 136.49 | 68.2 | Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. | L A Greene, A S Tischler | Proc Natl Acad Sci U S A | 1976 | 1065897 | Yes |
726 | 2621 | 2621.0 | 104.82 | 104.8 | The biology of oxygen radicals. | I Fridovich | Science | 1978 | 210504 | Yes |
727 | 5240 | 2620.0 | 117.26 | 58.6 | Signal transduction by receptors with tyrosine kinase activity. | A Ullrich, J Schlessinger | Cell | 1990 | 2158859 | No |
728 | 5239 | 2619.5 | 207.42 | 103.7 | A feature-integration theory of attention. | A M Treisman, G Gelade | Cogn Psychol | 1980 | 7351125 | Yes |
729 | 2614 | 2614.0 | 63.54 | 63.5 | Molecular basis of bacterial outer membrane permeability revisited. | Hiroshi Nikaido | Microbiol Mol Biol Rev | 2003 | 14665678 | No |
730 | 5222 | 2611.0 | 180.41 | 90.2 | A simple, rapid, and sensitive DNA assay procedure. | C Labarca, K Paigen | Anal Biochem | 1980 | 6158890 | Yes |
731 | 2611 | 2611.0 | 58.93 | 58.9 | Vascular endothelial growth factor: basic science and clinical progress. | Napoleone Ferrara | Endocr Rev | 2004 | 15294883 | No |
732 | 5221 | 2610.5 | 0.0 | 0.0 | Some quantitative uses of drug antagonists. | O Arunlakshana, H O Schild | Br J Pharmacol Chemother | 1959 | 13651579 | Yes |
733 | 2610 | 2610.0 | 116.82 | 116.8 | The membrane actions of anesthetics and tranquilizers. | P Seeman | Pharmacol Rev | 1972 | 4565956 | No |
734 | 2610 | 2610.0 | 81.38 | 81.4 | Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. | B Samuelsson | Science | 1983 | 6301011 | Yes |
735 | 5220 | 2610.0 | 159.43 | 79.7 | Rapid isolation of high molecular weight plant DNA. | M G Murray, W F Thompson | Nucleic Acids Res | 1980 | 7433111 | Yes |
736 | 2607 | 2607.0 | 74.53 | 74.5 | Formation and Structure of Self-Assembled Monolayers. | Abraham Ulman | Chem Rev | 1996 | 11848802 | Yes |
737 | 5196 | 2598.0 | 102.21 | 51.1 | Untangling the ErbB signalling network. | Y Yarden, M X Sliwkowski | Nat Rev Mol Cell Biol | 2001 | 11252954 | No |
738 | 15585 | 2597.5 | 349.48 | 58.2 | Phaser crystallographic software. | Airlie J McCoy, Ralf W Grosse-Kunstleve, Paul D Adams, Martyn D Winn, Laurent C Storoni, Randy J Read | J Appl Crystallogr | 2007 | 19461840 | Yes |
739 | 2596 | 2596.0 | 55.64 | 55.6 | G1 phase progression: cycling on cue. | C J Sherr | Cell | 1994 | 7954821 | No |
740 | 5182 | 2591.0 | 106.59 | 53.3 | MicroRNAs: small RNAs with a big role in gene regulation. | Lin He, Gregory J Hannon | Nat Rev Genet | 2004 | 15211354 | No |
741 | 2590 | 2590.0 | 62.29 | 62.3 | Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. | E C Butcher | Cell | 1991 | 1760836 | No |
742 | 2583 | 2583.0 | 0.0 | 0.0 | The hydrolysis of rabbit y-globulin and antibodies with crystalline papain. | R R Porter | Biochem J | 1959 | 14434282 | Yes |
743 | 5155 | 2577.5 | 159.54 | 79.8 | The L-arginine-nitric oxide pathway. | S Moncada, A Higgs | N Engl J Med | 1993 | 7504210 | No |
744 | 2577 | 2577.0 | 73.11 | 73.1 | Delayed neuronal death in the gerbil hippocampus following ischemia. | T Kirino | Brain Res | 1982 | 7093691 | Yes |
745 | 2575 | 2575.0 | 62.35 | 62.4 | Cancer nanotechnology: opportunities and challenges. | Mauro Ferrari | Nat Rev Cancer | 2005 | 15738981 | No |
746 | 2575 | 2575.0 | 56.97 | 57.0 | Epigenetics in cancer. | Manel Esteller | N Engl J Med | 2008 | 18337604 | No |
747 | 2566 | 2566.0 | 104.13 | 104.1 | Qualitative research. Introducing focus groups. | J Kitzinger | BMJ | 1995 | 7633241 | Yes |
748 | 5132 | 2566.0 | 166.52 | 83.3 | The neural basis of drug craving: an incentive-sensitization theory of addiction. | T E Robinson, K C Berridge | Brain Res Brain Res Rev | 1993 | 8401595 | No |
749 | 2564 | 2564.0 | 53.45 | 53.5 | Evolving concepts of rheumatoid arthritis. | Gary S Firestein | Nature | 2003 | 12748655 | No |
750 | 2562 | 2562.0 | 36.35 | 36.4 | The catecholamine hypothesis of affective disorders: a review of supporting evidence. | J J Schildkraut | Am J Psychiatry | 1965 | 5319766 | No |
751 | 2562 | 2562.0 | 50.26 | 50.3 | Tumour-educated macrophages promote tumour progression and metastasis. | Jeffrey W Pollard | Nat Rev Cancer | 2004 | 14708027 | No |
752 | 7685 | 2561.7 | 228.63 | 76.2 | FastTree 2--approximately maximum-likelihood trees for large alignments. | Morgan N Price, Paramvir S Dehal, Adam P Arkin | PLoS One | 2010 | 20224823 | Yes |
753 | 2561 | 2561.0 | 0.0 | 0.0 | The Estimation Of Pepsin, Trypsin, Papain, And Cathepsin With Hemoglobin. | M L Anson | J Gen Physiol | 1938 | 19873094 | Yes |
754 | 2561 | 2561.0 | 101.29 | 101.3 | Central sensitization: implications for the diagnosis and treatment of pain. | Clifford J Woolf | Pain | 2011 | 20961685 | No |
755 | 2558 | 2558.0 | 68.34 | 68.3 | Dominant forces in protein folding. | K A Dill | Biochemistry | 1990 | 2207096 | No |
756 | 5116 | 2558.0 | 80.92 | 40.5 | A general method applicable to the search for similarities in the amino acid sequence of two proteins. | S B Needleman, C D Wunsch | J Mol Biol | 1970 | 5420325 | Yes |
757 | 2558 | 2558.0 | 0.0 | 0.0 | Zone electrophoresis in starch gels: group variations in the serum proteins of normal human adults. | O Smithies | Biochem J | 1955 | 13276348 | Yes |
758 | 10203 | 2550.8 | 464.44 | 116.1 | IQ-TREE: a fast and effective stochastic algorithm for estimating maximum-likelihood phylogenies. | Lam-Tung Nguyen, Heiko A Schmidt, Arndt von Haeseler, Bui Quang Minh | Mol Biol Evol | 2015 | 25371430 | Yes |
759 | 2548 | 2548.0 | 71.47 | 71.5 | Two-sided confidence intervals for the single proportion: comparison of seven methods. | R G Newcombe | Stat Med | 1998 | 9595616 | Yes |
760 | 2544 | 2544.0 | 72.96 | 73.0 | Stress, adaptation, and disease. Allostasis and allostatic load. | B S McEwen | Ann N Y Acad Sci | 1998 | 9629234 | No |
761 | 2540 | 2540.0 | 26.62 | 26.6 | The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes. | S Boyden | J Exp Med | 1962 | 13872176 | Yes |
762 | 2539 | 2539.0 | 51.95 | 52.0 | Telomere measurement by quantitative PCR. | Richard M Cawthon | Nucleic Acids Res | 2002 | 12000852 | Yes |
763 | 10150 | 2537.5 | 1506.74 | 376.7 | Cancer Statistics, 2021. | Rebecca L Siegel, Kimberly D Miller, Hannah E Fuchs, Ahmedin Jemal | CA Cancer J Clin | 2021 | 33433946 | Yes |
764 | 2537 | 2537.0 | 51.04 | 51.0 | Universal control mechanism regulating onset of M-phase. | P Nurse | Nature | 1990 | 2138713 | No |
765 | 2536 | 2536.0 | 55.09 | 55.1 | Angiogenesis in life, disease and medicine. | Peter Carmeliet | Nature | 2005 | 16355210 | No |
766 | 7604 | 2534.7 | 261.13 | 87.0 | Effect of the damping function in dispersion corrected density functional theory. | Stefan Grimme, Stephan Ehrlich, Lars Goerigk | J Comput Chem | 2011 | 21370243 | Yes |
767 | 5060 | 2530.0 | 273.63 | 136.8 | A diagnostic interview: the schedule for affective disorders and schizophrenia. | J Endicott, R L Spitzer | Arch Gen Psychiatry | 1978 | 678037 | Yes |
768 | 2530 | 2530.0 | 77.65 | 77.7 | Secretory products of macrophages. | C F Nathan | J Clin Invest | 1987 | 3543052 | No |
769 | 5060 | 2530.0 | 231.85 | 115.9 | Periodontal Disease In Pregnancy. Ii. Correlation Between Oral Hygiene And Periodontal Condtion. | J Silness, H Loe | Acta Odontol Scand | 1964 | 14158464 | Yes |
770 | 2525 | 2525.0 | 87.47 | 87.5 | A computational approach to edge detection. | J Canny | IEEE Trans Pattern Anal Mach Intell | 1986 | 21869365 | Yes |
771 | 5047 | 2523.5 | 125.01 | 62.5 | Reactive oxygen species: metabolism, oxidative stress, and signal transduction. | Klaus Apel, Heribert Hirt | Annu Rev Plant Biol | 2004 | 15377225 | No |
772 | 2522 | 2522.0 | 70.23 | 70.2 | Physiology and neurobiology of stress and adaptation: central role of the brain. | Bruce S McEwen | Physiol Rev | 2007 | 17615391 | No |
773 | 2516 | 2516.0 | 79.94 | 79.9 | Social cognitive theory: an agentic perspective. | A Bandura | Annu Rev Psychol | 2001 | 11148297 | Yes |
774 | 2515 | 2515.0 | 61.69 | 61.7 | A mechanism for cognitive dynamics: neuronal communication through neuronal coherence. | Pascal Fries | Trends Cogn Sci | 2005 | 16150631 | No |
775 | 2515 | 2515.0 | 108.18 | 108.2 | Statistics corner: A guide to appropriate use of correlation coefficient in medical research. | M M Mukaka | Malawi Med J | 2012 | 23638278 | Yes |
776 | 2514 | 2514.0 | 70.18 | 70.2 | Human gastric carcinogenesis: a multistep and multifactorial process--First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. | P Correa | Cancer Res | 1992 | 1458460 | No |
777 | 2508 | 2508.0 | 82.42 | 82.4 | A rating instrument for anxiety disorders. | W W Zung | Psychosomatics | 1971 | 5172928 | Yes |
778 | 2502 | 2502.0 | 78.11 | 78.1 | The free-energy principle: a unified brain theory? | Karl Friston | Nat Rev Neurosci | 2010 | 20068583 | No |
779 | 2498 | 2498.0 | 44.97 | 45.0 | Wnt signaling and cancer. | P Polakis | Genes Dev | 2000 | 10921899 | No |
780 | 4993 | 2496.5 | 179.4 | 89.7 | Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril. | P J Fraker, J C Speck | Biochem Biophys Res Commun | 1978 | 637870 | Yes |
781 | 2492 | 2492.0 | 148.8 | 148.8 | Hepatocellular Carcinoma. | Augusto Villanueva | N Engl J Med | 2019 | 30970190 | No |
782 | 9961 | 2490.2 | 411.68 | 102.9 | Cancer statistics, 2014. | Rebecca Siegel, Jiemin Ma, Zhaohui Zou, Ahmedin Jemal | CA Cancer J Clin | 2014 | 24399786 | Yes |
783 | 2488 | 2488.0 | 66.01 | 66.0 | Evaluating the quality of medical care. | A Donabedian | Milbank Mem Fund Q | 1966 | 5338568 | No |
784 | 2486 | 2486.0 | 112.08 | 112.1 | Oxygen-dependent microbial killing by phagocytes (first of two parts). | B M Babior | N Engl J Med | 1978 | 24176 | Yes |
785 | 4966 | 2483.0 | 141.52 | 70.8 | Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. | J V Durnin, J Womersley | Br J Nutr | 1974 | 4843734 | Yes |
786 | 2482 | 2482.0 | 81.21 | 81.2 | Perceived exertion as an indicator of somatic stress. | G Borg | Scand J Rehabil Med | 1970 | 5523831 | Yes |
787 | 4950 | 2475.0 | 99.36 | 49.7 | Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. | D Bonnet, J E Dick | Nat Med | 1997 | 9212098 | Yes |
788 | 4947 | 2473.5 | 118.85 | 59.4 | Calculation of protein extinction coefficients from amino acid sequence data. | S C Gill, P H von Hippel | Anal Biochem | 1989 | 2610349 | Yes |
789 | 4946 | 2473.0 | 96.31 | 48.2 | CDK inhibitors: positive and negative regulators of G1-phase progression. | C J Sherr, J M Roberts | Genes Dev | 1999 | 10385618 | No |
790 | 4912 | 2456.0 | 215.79 | 107.9 | Clinical significance: a statistical approach to defining meaningful change in psychotherapy research. | N S Jacobson, P Truax | J Consult Clin Psychol | 1991 | 2002127 | Yes |
791 | 7366 | 2455.3 | 200.56 | 66.9 | Quantum mechanical continuum solvation models. | Jacopo Tomasi, Benedetta Mennucci, Roberto Cammi | Chem Rev | 2005 | 16092826 | Yes |
792 | 2452 | 2452.0 | 54.46 | 54.5 | Social controls on cell survival and cell death. | M C Raff | Nature | 1992 | 1557121 | No |
793 | 4902 | 2451.0 | 114.48 | 57.2 | Myeloid-derived suppressor cells as regulators of the immune system. | Dmitry I Gabrilovich, Srinivas Nagaraj | Nat Rev Immunol | 2009 | 19197294 | No |
794 | 7352 | 2450.7 | 184.93 | 61.6 | RNA-Seq: a revolutionary tool for transcriptomics. | Zhong Wang, Mark Gerstein, Michael Snyder | Nat Rev Genet | 2009 | 19015660 | No |
795 | 7340 | 2446.7 | 196.12 | 65.4 | Immunity, inflammation, and cancer. | Sergei I Grivennikov, Florian R Greten, Michael Karin | Cell | 2010 | 20303878 | No |
796 | 2444 | 2444.0 | 0.0 | 0.0 | Transduction of linked genetic characters of the host by bacteriophage P1. | E S Lennox | Virology | 1955 | 13267987 | Yes |
797 | 2443 | 2443.0 | 47.33 | 47.3 | Getting started with yeast. | F Sherman | Methods Enzymol | 1991 | 2005794 | Yes |
798 | 2443 | 2443.0 | 65.72 | 65.7 | Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication. | H G Gratzner | Science | 1982 | 7123245 | Yes |
799 | 4870 | 2435.0 | 145.15 | 72.6 | SPSS and SAS procedures for estimating indirect effects in simple mediation models. | Kristopher J Preacher, Andrew F Hayes | Behav Res Methods Instrum Comput | 2004 | 15641418 | Yes |
800 | 2431 | 2431.0 | 61.02 | 61.0 | Immunological and inflammatory functions of the interleukin-1 family. | Charles A Dinarello | Annu Rev Immunol | 2009 | 19302047 | No |
801 | 2430 | 2430.0 | 122.83 | 122.8 | Conservation of resources. A new attempt at conceptualizing stress. | S E Hobfoll | Am Psychol | 1989 | 2648906 | No |
802 | 2424 | 2424.0 | 57.99 | 58.0 | Causes and consequences of microRNA dysregulation in cancer. | Carlo M Croce | Nat Rev Genet | 2009 | 19763153 | No |
803 | 4842 | 2421.0 | 125.81 | 62.9 | UniFrac: a new phylogenetic method for comparing microbial communities. | Catherine Lozupone, Rob Knight | Appl Environ Microbiol | 2005 | 16332807 | Yes |
804 | 4831 | 2415.5 | 120.63 | 60.3 | A global optimisation method for robust affine registration of brain images. | M Jenkinson, S Smith | Med Image Anal | 2001 | 11516708 | Yes |
805 | 9657 | 2414.2 | 253.7 | 63.4 | GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation. | Berk Hess, Carsten Kutzner, David van der Spoel, Erik Lindahl | J Chem Theory Comput | 2008 | 26620784 | Yes |
806 | 7238 | 2412.7 | 206.43 | 68.8 | Bacterial biofilms: a common cause of persistent infections. | J W Costerton, P S Stewart, E P Greenberg | Science | 1999 | 10334980 | No |
807 | 2409 | 2409.0 | 92.21 | 92.2 | Missing data analysis: making it work in the real world. | John W Graham | Annu Rev Psychol | 2009 | 18652544 | No |
808 | 4814 | 2407.0 | 107.41 | 53.7 | Signal integration in the endoplasmic reticulum unfolded protein response. | David Ron, Peter Walter | Nat Rev Mol Cell Biol | 2007 | 17565364 | No |
809 | 7215 | 2405.0 | 186.72 | 62.2 | Cortical surface-based analysis. I. Segmentation and surface reconstruction. | A M Dale, B Fischl, M I Sereno | Neuroimage | 1999 | 9931268 | Yes |
810 | 2403 | 2403.0 | 52.33 | 52.3 | Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. | T Hunter | Cell | 1995 | 7834742 | No |
811 | 2402 | 2402.0 | 77.03 | 77.0 | Plant products as antimicrobial agents. | M M Cowan | Clin Microbiol Rev | 1999 | 10515903 | No |
812 | 4798 | 2399.0 | 93.01 | 46.5 | The phosphatidylinositol 3-Kinase AKT pathway in human cancer. | Igor Vivanco, Charles L Sawyers | Nat Rev Cancer | 2002 | 12094235 | No |
813 | 2399 | 2399.0 | 0.0 | 0.0 | The information capacity of the human motor system in controlling the amplitude of movement. | P M Fitts | J Exp Psychol | 1954 | 13174710 | Yes |
814 | 2397 | 2397.0 | 94.33 | 94.3 | The biology and function of fibroblasts in cancer. | Raghu Kalluri | Nat Rev Cancer | 2016 | 27550820 | No |
815 | 4787 | 2393.5 | 119.9 | 60.0 | The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. | Karen Bedard, Karl-Heinz Krause | Physiol Rev | 2007 | 17237347 | No |
816 | 4785 | 2392.5 | 94.36 | 47.2 | Lipid rafts and signal transduction. | K Simons, D Toomre | Nat Rev Mol Cell Biol | 2000 | 11413487 | No |
817 | 2388 | 2388.0 | 73.84 | 73.8 | The role of positive emotions in positive psychology. The broaden-and-build theory of positive emotions. | B L Fredrickson | Am Psychol | 2001 | 11315248 | Yes |
818 | 4767 | 2383.5 | 152.12 | 76.1 | Microenvironmental regulation of tumor progression and metastasis. | Daniela F Quail, Johanna A Joyce | Nat Med | 2013 | 24202395 | No |
819 | 2379 | 2379.0 | 49.69 | 49.7 | Molecular physiology of P2X receptors. | R Alan North | Physiol Rev | 2002 | 12270951 | No |
820 | 4756 | 2378.0 | 126.69 | 63.3 | Alzheimer's disease: the amyloid cascade hypothesis. | J A Hardy, G A Higgins | Science | 1992 | 1566067 | No |
821 | 2378 | 2378.0 | 49.9 | 49.9 | Cisplatin: mode of cytotoxic action and molecular basis of resistance. | Zahid H Siddik | Oncogene | 2003 | 14576837 | No |
822 | 2375 | 2375.0 | 60.07 | 60.1 | Inferring the historical patterns of biological evolution. | M Pagel | Nature | 1999 | 10553904 | Yes |
823 | 4750 | 2375.0 | 48.82 | 24.4 | Periodontal Disease In Pregnancy. I. Prevalence And Severity. | H Loe, J Silness | Acta Odontol Scand | 1963 | 14121956 | Yes |
824 | 4743 | 2371.5 | 120.22 | 60.1 | Management of hepatocellular carcinoma. | Jordi Bruix, Morris Sherman | Hepatology | 2005 | 16250051 | No |
825 | 2370 | 2370.0 | 107.83 | 107.8 | Structural Model Evaluation and Modification: An Interval Estimation Approach. | J H Steiger | Multivariate Behav Res | 1990 | 26794479 | Yes |
826 | 2369 | 2369.0 | 43.38 | 43.4 | Java Treeview--extensible visualization of microarray data. | Alok J Saldanha | Bioinformatics | 2004 | 15180930 | Yes |
827 | 4737 | 2368.5 | 140.94 | 70.5 | Neural mechanisms of selective visual attention. | R Desimone, J Duncan | Annu Rev Neurosci | 1995 | 7605061 | No |
828 | 2368 | 2368.0 | 54.11 | 54.1 | A decade of molecular biology of retinoic acid receptors. | P Chambon | FASEB J | 1996 | 8801176 | No |
829 | 2367 | 2367.0 | 80.19 | 80.2 | A rapid radiochemical method for the determination of choline acetyltransferase. | F Fonnum | J Neurochem | 1975 | 1113118 | Yes |
830 | 2367 | 2367.0 | 82.06 | 82.1 | Doxil®--the first FDA-approved nano-drug: lessons learned. | Yechezkel Barenholz | J Control Release | 2012 | 22484195 | No |
831 | 4733 | 2366.5 | 154.42 | 77.2 | Random-effects models for longitudinal data. | N M Laird, J H Ware | Biometrics | 1982 | 7168798 | Yes |
832 | 2361 | 2361.0 | 67.12 | 67.1 | Scaffolds in tissue engineering bone and cartilage. | D W Hutmacher | Biomaterials | 2000 | 11071603 | Yes |
833 | 4720 | 2360.0 | 103.57 | 51.8 | Death receptors: signaling and modulation. | A Ashkenazi, V M Dixit | Science | 1998 | 9721089 | No |
834 | 2359 | 2359.0 | 52.03 | 52.0 | Rab GTPases as coordinators of vesicle traffic. | Harald Stenmark | Nat Rev Mol Cell Biol | 2009 | 19603039 | No |
835 | 2357 | 2357.0 | 117.34 | 117.3 | Electroimmuno assay. | C B Laurell | Scand J Clin Lab Invest Suppl | 1972 | 4114358 | Yes |
836 | 2356 | 2356.0 | 75.96 | 76.0 | Epidemiology of viral hepatitis and hepatocellular carcinoma. | Hashem B El-Serag | Gastroenterology | 2012 | 22537432 | No |
837 | 2354 | 2354.0 | 57.25 | 57.2 | The anatomy and taxonomy of protein structure. | J S Richardson | Adv Protein Chem | 1981 | 7020376 | No |
838 | 2353 | 2353.0 | 101.79 | 101.8 | The Michigan alcoholism screening test: the quest for a new diagnostic instrument. | M L Selzer | Am J Psychiatry | 1971 | 5565851 | Yes |
839 | 2352 | 2352.0 | 45.08 | 45.1 | Mechanisms of type-I- and type-II-interferon-mediated signalling. | Leonidas C Platanias | Nat Rev Immunol | 2005 | 15864272 | No |
840 | 4702 | 2351.0 | 139.06 | 69.5 | Missing data: our view of the state of the art. | Joseph L Schafer, John W Graham | Psychol Methods | 2002 | 12090408 | Yes |
841 | 2348 | 2348.0 | 78.21 | 78.2 | Working memory. | A Baddeley | Science | 1992 | 1736359 | No |
842 | 2348 | 2348.0 | 53.0 | 53.0 | The inflammatory reflex. | Kevin J Tracey | Nature | 2002 | 12490958 | No |
843 | 4693 | 2346.5 | 97.69 | 48.8 | New functions for the matrix metalloproteinases in cancer progression. | Mikala Egeblad, Zena Werb | Nat Rev Cancer | 2002 | 11990853 | No |
844 | 2346 | 2346.0 | 43.1 | 43.1 | Targeting RAS signalling pathways in cancer therapy. | Julian Downward | Nat Rev Cancer | 2003 | 12509763 | No |
845 | 7036 | 2345.3 | 70.26 | 23.4 | On The Nature Of Allosteric Transitions: A Plausible Model. | J Monod, J Wyman, J P Changeux | J Mol Biol | 1965 | 14343300 | Yes |
846 | 2345 | 2345.0 | 51.72 | 51.7 | Mitochondrial diseases in man and mouse. | D C Wallace | Science | 1999 | 10066162 | No |
847 | 2343 | 2343.0 | 50.95 | 51.0 | A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. | Douglas C Wallace | Annu Rev Genet | 2005 | 16285865 | No |
848 | 4685 | 2342.5 | 135.83 | 67.9 | Nonparametric statistical testing of EEG- and MEG-data. | Eric Maris, Robert Oostenveld | J Neurosci Methods | 2007 | 17517438 | Yes |
849 | 2342 | 2342.0 | 51.84 | 51.8 | The structure and regulation of protein phosphatases. | P Cohen | Annu Rev Biochem | 1989 | 2549856 | No |
850 | 7026 | 2342.0 | 153.95 | 51.3 | The biology of VEGF and its receptors. | Napoleone Ferrara, Hans-Peter Gerber, Jennifer LeCouter | Nat Med | 2003 | 12778165 | No |
851 | 4679 | 2339.5 | 100.67 | 50.3 | Judgment under Uncertainty: Heuristics and Biases. | A Tversky, D Kahneman | Science | 1974 | 17835457 | Yes |
852 | 2338 | 2338.0 | 0.0 | 0.0 | Isolation by Distance. | S Wright | Genetics | 1943 | 17247074 | Yes |
853 | 4674 | 2337.0 | 103.22 | 51.6 | Screening lambdagt recombinant clones by hybridization to single plaques in situ. | W D Benton, R W Davis | Science | 1977 | 322279 | Yes |
854 | 2335 | 2335.0 | 0.0 | 0.0 | Muscle structure and theories of contraction. | A F Huxley | Prog Biophys Biophys Chem | 1957 | 13485191 | Yes |
855 | 6999 | 2333.0 | 184.94 | 61.6 | Regularization Paths for Generalized Linear Models via Coordinate Descent. | Jerome Friedman, Trevor Hastie, Rob Tibshirani | J Stat Softw | 2010 | 20808728 | Yes |
856 | 4663 | 2331.5 | 126.87 | 63.4 | Ab initio molecular-dynamics simulation of the liquid-metal-amorphous-semiconductor transition in germanium. | G Kresse, J Hafner | Phys Rev B Condens Matter | 1994 | 10010505 | Yes |
857 | 2331 | 2331.0 | 84.26 | 84.3 | Calmodulin plays a pivotal role in cellular regulation. | W Y Cheung | Science | 1980 | 6243188 | No |
858 | 2328 | 2328.0 | 79.96 | 80.0 | Gctf: Real-time CTF determination and correction. | Kai Zhang | J Struct Biol | 2016 | 26592709 | Yes |
859 | 4655 | 2327.5 | 118.52 | 59.3 | Gold nanoparticles: assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology. | Marie-Christine Daniel, Didier Astruc | Chem Rev | 2004 | 14719978 | No |
860 | 2327 | 2327.0 | 61.1 | 61.1 | A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. | P Chomczynski | Biotechniques | 1993 | 7692896 | Yes |
861 | 4652 | 2326.0 | 87.26 | 43.6 | A novel genetic system to detect protein-protein interactions. | S Fields, O Song | Nature | 1989 | 2547163 | Yes |
862 | 4645 | 2322.5 | 131.41 | 65.7 | The number of people with glaucoma worldwide in 2010 and 2020. | H A Quigley, A T Broman | Br J Ophthalmol | 2006 | 16488940 | Yes |
863 | 2321 | 2321.0 | 57.47 | 57.5 | A model for receptor-regulated calcium entry. | J W Putney | Cell Calcium | 1986 | 2420465 | No |
864 | 4641 | 2320.5 | 129.58 | 64.8 | Quantitative film detection of 3H and 14C in polyacrylamide gels by fluorography. | R A Laskey, A D Mills | Eur J Biochem | 1975 | 1175627 | Yes |
865 | 2320 | 2320.0 | 66.25 | 66.2 | Interleukin-1 and interleukin-1 antagonism. | C A Dinarello | Blood | 1991 | 1826616 | No |
866 | 4640 | 2320.0 | 195.08 | 97.5 | The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. | H P Misra, I Fridovich | J Biol Chem | 1972 | 4623845 | Yes |
867 | 2319 | 2319.0 | 46.75 | 46.8 | Stereochemistry of cooperative effects in haemoglobin. | M F Perutz | Nature | 1970 | 5528785 | Yes |
868 | 2317 | 2317.0 | 90.32 | 90.3 | Effective physician-patient communication and health outcomes: a review. | M A Stewart | CMAJ | 1995 | 7728691 | Yes |
869 | 4634 | 2317.0 | 126.39 | 63.2 | Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. | Michael D Fox, Marcus E Raichle | Nat Rev Neurosci | 2007 | 17704812 | No |
870 | 2316 | 2316.0 | 65.65 | 65.7 | Inositol phospholipids and cell surface receptor function. | R H Michell | Biochim Biophys Acta | 1975 | 164246 | No |
871 | 2314 | 2314.0 | 55.33 | 55.3 | Ischemic cell death in brain neurons. | P Lipton | Physiol Rev | 1999 | 10508238 | No |
872 | 4625 | 2312.5 | 160.6 | 80.3 | The biofilm matrix. | Hans-Curt Flemming, Jost Wingender | Nat Rev Microbiol | 2010 | 20676145 | No |
873 | 4618 | 2309.0 | 122.11 | 61.1 | Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. | C W Elston, I O Ellis | Histopathology | 1991 | 1757079 | Yes |
874 | 2309 | 2309.0 | 57.14 | 57.1 | Bcl-2 and the regulation of programmed cell death. | J C Reed | J Cell Biol | 1994 | 8294493 | No |
875 | 4612 | 2306.0 | 102.25 | 51.1 | AKT/PKB signaling: navigating downstream. | Brendan D Manning, Lewis C Cantley | Cell | 2007 | 17604717 | No |
876 | 2304 | 2304.0 | 48.71 | 48.7 | NOX enzymes and the biology of reactive oxygen. | J David Lambeth | Nat Rev Immunol | 2004 | 15039755 | No |
877 | 4600 | 2300.0 | 116.1 | 58.0 | Acute-phase proteins and other systemic responses to inflammation. | C Gabay, I Kushner | N Engl J Med | 1999 | 9971870 | No |
878 | 4599 | 2299.5 | 77.99 | 39.0 | High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study. | M N Berry, D S Friend | J Cell Biol | 1969 | 4900611 | Yes |
879 | 4596 | 2298.0 | 74.03 | 37.0 | On the size of the active site in proteases. I. Papain. | I Schechter, A Berger | Biochem Biophys Res Commun | 1967 | 6035483 | Yes |
880 | 2298 | 2298.0 | 56.3 | 56.3 | An index to quantify an individual's scientific research output. | J E Hirsch | Proc Natl Acad Sci U S A | 2005 | 16275915 | Yes |
881 | 2296 | 2296.0 | 71.58 | 71.6 | Reactive oxygen species and the central nervous system. | B Halliwell | J Neurochem | 1992 | 1402908 | No |
882 | 2296 | 2296.0 | 58.3 | 58.3 | Network pharmacology: the next paradigm in drug discovery. | Andrew L Hopkins | Nat Chem Biol | 2008 | 18936753 | No |
883 | 2295 | 2295.0 | 531.73 | 531.7 | Hallmarks of Cancer: New Dimensions. | Douglas Hanahan | Cancer Discov | 2022 | 35022204 | No |
884 | 2291 | 2291.0 | 19.35 | 19.4 | Mechanism Of Sustained-Action Medication. Theoretical Analysis Of Rate Of Release Of Solid Drugs Dispersed In Solid Matrices. | T Higuchi | J Pharm Sci | 1963 | 14088963 | Yes |
885 | 4580 | 2290.0 | 116.05 | 58.0 | A receptor-mediated pathway for cholesterol homeostasis. | M S Brown, J L Goldstein | Science | 1986 | 3513311 | No |
886 | 2290 | 2290.0 | 49.76 | 49.8 | Nitric oxide and the immune response. | C Bogdan | Nat Immunol | 2001 | 11577346 | No |
887 | 4574 | 2287.0 | 88.96 | 44.5 | Mechanisms of TGF-beta signaling from cell membrane to the nucleus. | Yigong Shi, Joan Massagué | Cell | 2003 | 12809600 | No |
888 | 2286 | 2286.0 | 78.54 | 78.5 | Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. | F F Jöbsis | Science | 1977 | 929199 | Yes |
889 | 2286 | 2286.0 | 45.25 | 45.2 | SV40-transformed simian cells support the replication of early SV40 mutants. | Y Gluzman | Cell | 1981 | 6260373 | Yes |
890 | 2286 | 2286.0 | 69.42 | 69.4 | A two process model of sleep regulation. | A A Borbély | Hum Neurobiol | 1982 | 7185792 | Yes |
891 | 4571 | 2285.5 | 168.07 | 84.0 | Self-rated health and mortality: a review of twenty-seven community studies. | E L Idler, Y Benyamini | J Health Soc Behav | 1997 | 9097506 | No |
892 | 4569 | 2284.5 | 89.73 | 44.9 | The interpretation of protein structures: estimation of static accessibility. | B Lee, F M Richards | J Mol Biol | 1971 | 5551392 | Yes |
893 | 2283 | 2283.0 | 61.65 | 61.6 | Intestinal mucosal barrier function in health and disease. | Jerrold R Turner | Nat Rev Immunol | 2009 | 19855405 | No |
894 | 4565 | 2282.5 | 167.17 | 83.6 | The attention system of the human brain. | M I Posner, S E Petersen | Annu Rev Neurosci | 1990 | 2183676 | No |
895 | 2282 | 2282.0 | 93.95 | 94.0 | The validity and practicality of sun-reactive skin types I through VI. | T B Fitzpatrick | Arch Dermatol | 1988 | 3377516 | Yes |
896 | 2282 | 2282.0 | 56.21 | 56.2 | Contrasting mechanisms of defense against biotrophic and necrotrophic pathogens. | Jane Glazebrook | Annu Rev Phytopathol | 2005 | 16078883 | No |
897 | 4559 | 2279.5 | 107.37 | 53.7 | Protein misfolding, functional amyloid, and human disease. | Fabrizio Chiti, Christopher M Dobson | Annu Rev Biochem | 2006 | 16756495 | No |
898 | 9109 | 2277.2 | 217.95 | 54.5 | Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. | C A Lipinski, F Lombardo, B W Dominy, P J Feeney | Adv Drug Deliv Rev | 2001 | 11259830 | No |
899 | 2277 | 2277.0 | 76.2 | 76.2 | Glutamate, nitric oxide and cell-cell signalling in the nervous system. | J Garthwaite | Trends Neurosci | 1991 | 1708538 | No |
900 | 2277 | 2277.0 | 0.0 | 0.0 | [Rapid physiological coagulation method in determination of fibrinogen]. | A Clauss | Acta Haematol | 1957 | 13434757 | Yes |
901 | 2276 | 2276.0 | 53.13 | 53.1 | Specification of cerebral cortical areas. | P Rakic | Science | 1988 | 3291116 | No |
902 | 2274 | 2274.0 | 104.54 | 104.5 | Deep learning in neural networks: an overview. | Jürgen Schmidhuber | Neural Netw | 2015 | 25462637 | No |
903 | 2273 | 2273.0 | 49.18 | 49.2 | Chemokines and leukocyte traffic. | M Baggiolini | Nature | 1998 | 9560152 | No |
904 | 4546 | 2273.0 | 111.2 | 55.6 | Nonparametric permutation tests for functional neuroimaging: a primer with examples. | Thomas E Nichols, Andrew P Holmes | Hum Brain Mapp | 2002 | 11747097 | Yes |
905 | 2273 | 2273.0 | 57.61 | 57.6 | A theory of cortical responses. | Karl Friston | Philos Trans R Soc Lond B Biol Sci | 2005 | 15937014 | No |
906 | 2272 | 2272.0 | 42.84 | 42.8 | Histone acetylation in chromatin structure and transcription. | M Grunstein | Nature | 1997 | 9311776 | No |
907 | 2270 | 2270.0 | 71.15 | 71.2 | Human error: models and management. | J Reason | BMJ | 2000 | 10720363 | Yes |
908 | 4533 | 2266.5 | 122.17 | 61.1 | Application of phylogenetic networks in evolutionary studies. | Daniel H Huson, David Bryant | Mol Biol Evol | 2006 | 16221896 | Yes |
909 | 2263 | 2263.0 | 60.11 | 60.1 | The importance of selenium to human health. | M P Rayman | Lancet | 2000 | 10963212 | No |
910 | 2261 | 2261.0 | 68.93 | 68.9 | Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM. | R A DeFronzo | Diabetes | 1988 | 3289989 | No |
911 | 2261 | 2261.0 | 47.24 | 47.2 | Application of a microtechnique to viral serological investigations. | J L Sever | J Immunol | 1962 | 13910995 | Yes |
912 | 9021 | 2255.2 | 198.07 | 49.5 | Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. | A Krogh, B Larsson, G von Heijne, E L Sonnhammer | J Mol Biol | 2001 | 11152613 | Yes |
913 | 4508 | 2254.0 | 94.96 | 47.5 | Mass spectrometry-based proteomics. | Ruedi Aebersold, Matthias Mann | Nature | 2003 | 12634793 | No |
914 | 2252 | 2252.0 | 75.43 | 75.4 | Simplified calculation of body-surface area. | R D Mosteller | N Engl J Med | 1987 | 3657876 | Yes |
915 | 2251 | 2251.0 | 44.62 | 44.6 | The molecular biology of memory storage: a dialogue between genes and synapses. | E R Kandel | Science | 2001 | 11691980 | No |
916 | 2251 | 2251.0 | 58.13 | 58.1 | The blood-brain barrier in health and chronic neurodegenerative disorders. | Berislav V Zlokovic | Neuron | 2008 | 18215617 | No |
917 | 2251 | 2251.0 | 59.02 | 59.0 | MYC on the path to cancer. | Chi V Dang | Cell | 2012 | 22464321 | No |
918 | 2250 | 2250.0 | 0.0 | 0.0 | Studies on lysogenesis. I. The mode of phage liberation by lysogenic Escherichia coli. | G Bertani | J Bacteriol | 1951 | 14888646 | Yes |
919 | 4498 | 2249.0 | 102.84 | 51.4 | A simple and very efficient method for generating cDNA libraries. | U Gubler, B J Hoffman | Gene | 1983 | 6198242 | Yes |
920 | 2248 | 2248.0 | 73.04 | 73.0 | Eye movements in reading and information processing: 20 years of research. | K Rayner | Psychol Bull | 1998 | 9849112 | No |
921 | 2245 | 2245.0 | 61.54 | 61.5 | Molecular diversity of glutamate receptors and implications for brain function. | S Nakanishi | Science | 1992 | 1329206 | No |
922 | 2243 | 2243.0 | 109.27 | 109.3 | Mechanisms of action of transmitters and other substances on smooth muscle. | T B Bolton | Physiol Rev | 1979 | 37533 | No |
923 | 2243 | 2243.0 | 49.17 | 49.2 | Intracellular aspects of the process of protein synthesis. | G Palade | Science | 1975 | 1096303 | No |
924 | 2241 | 2241.0 | 53.1 | 53.1 | Protein kinase C and lipid signaling for sustained cellular responses. | Y Nishizuka | FASEB J | 1995 | 7737456 | No |
925 | 2241 | 2241.0 | 114.12 | 114.1 | The antibiotic resistance crisis: part 1: causes and threats. | C Lee Ventola | P T | 2015 | 25859123 | Yes |
926 | 2240 | 2240.0 | 83.65 | 83.7 | Specific impairments of planning. | T Shallice | Philos Trans R Soc Lond B Biol Sci | 1982 | 6125971 | Yes |
927 | 2240 | 2240.0 | 52.83 | 52.8 | Mechanisms and genes of cellular suicide. | H Steller | Science | 1995 | 7878463 | No |
928 | 2240 | 2240.0 | 55.96 | 56.0 | RGD and other recognition sequences for integrins. | E Ruoslahti | Annu Rev Cell Dev Biol | 1996 | 8970741 | No |
929 | 2240 | 2240.0 | 73.4 | 73.4 | Qualitative research: standards, challenges, and guidelines. | K Malterud | Lancet | 2001 | 11513933 | Yes |
930 | 2239 | 2239.0 | 123.35 | 123.3 | Determination and quantification of content validity. | M R Lynn | Nurs Res | 1986 | 3640358 | Yes |
931 | 2238 | 2238.0 | 54.87 | 54.9 | Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide to nitrocellulose. | J Kyhse-Andersen | J Biochem Biophys Methods | 1984 | 6530509 | Yes |
932 | 2238 | 2238.0 | 59.75 | 59.8 | Carbonic anhydrases: novel therapeutic applications for inhibitors and activators. | Claudiu T Supuran | Nat Rev Drug Discov | 2008 | 18167490 | No |
933 | 2236 | 2236.0 | 77.56 | 77.6 | Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases. | B N Ames | Science | 1983 | 6351251 | No |
934 | 2236 | 2236.0 | 71.22 | 71.2 | Spinal and supraspinal factors in human muscle fatigue. | S C Gandevia | Physiol Rev | 2001 | 11581501 | No |
935 | 4462 | 2231.0 | 108.68 | 54.3 | A scaling normalization method for differential expression analysis of RNA-seq data. | Mark D Robinson, Alicia Oshlack | Genome Biol | 2010 | 20196867 | Yes |
936 | 4455 | 2227.5 | 108.0 | 54.0 | Regulation of the mevalonate pathway. | J L Goldstein, M S Brown | Nature | 1990 | 1967820 | No |
937 | 2227 | 2227.0 | 49.03 | 49.0 | The regulation of AP-1 activity by mitogen-activated protein kinases. | M Karin | J Biol Chem | 1995 | 7622446 | No |
938 | 2227 | 2227.0 | 57.89 | 57.9 | Working memory: looking back and looking forward. | Alan Baddeley | Nat Rev Neurosci | 2003 | 14523382 | No |
939 | 4452 | 2226.0 | 128.62 | 64.3 | Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. | C J Murray, A D Lopez | Lancet | 1997 | 9167458 | Yes |
940 | 4451 | 2225.5 | 98.07 | 49.0 | Organization and expression of eucaryotic split genes coding for proteins. | R Breathnach, P Chambon | Annu Rev Biochem | 1981 | 6791577 | No |
941 | 4450 | 2225.0 | 39.65 | 19.8 | A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. | J E TILL, E A McCULLOCH | Radiat Res | 1961 | 13776896 | Yes |
942 | 2223 | 2223.0 | 63.53 | 63.5 | TGFβ signalling in context. | Joan Massagué | Nat Rev Mol Cell Biol | 2012 | 22992590 | No |
943 | 4444 | 2222.0 | 87.95 | 44.0 | Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. | T V Bliss, T Lomo | J Physiol | 1973 | 4727084 | Yes |
944 | 2221 | 2221.0 | 68.64 | 68.6 | Biodiesel from microalgae. | Yusuf Chisti | Biotechnol Adv | 2007 | 17350212 | No |
945 | 4439 | 2219.5 | 91.27 | 45.6 | The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin. | J A Spudich, S Watt | J Biol Chem | 1971 | 4254541 | Yes |
946 | 2219 | 2219.0 | 53.94 | 53.9 | Animal mitochondrial genomes. | J L Boore | Nucleic Acids Res | 1999 | 10101183 | No |
947 | 2217 | 2217.0 | 58.28 | 58.3 | Epidemiology of insomnia: what we know and what we still need to learn. | Maurice M Ohayon | Sleep Med Rev | 2002 | 12531146 | Yes |
948 | 17728 | 2216.0 | 558.93 | 69.9 | The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. | D M Nathan, S Genuth, J Lachin, P Cleary, O Crofford, M Davis, L Rand, C Siebert | N Engl J Med | 1993 | 8366922 | Yes |
949 | 2214 | 2214.0 | 137.46 | 137.5 | Presidential Address-1976. Social support as a moderator of life stress. | S Cobb | Psychosom Med | 1976 | 981490 | Yes |
950 | 2214 | 2214.0 | 64.43 | 64.4 | Hazards of heavy metal contamination. | Lars Järup | Br Med Bull | 2003 | 14757716 | No |
951 | 2212 | 2212.0 | 68.05 | 68.0 | Prooxidant states and tumor promotion. | P A Cerutti | Science | 1985 | 2981433 | No |
952 | 2212 | 2212.0 | 83.33 | 83.3 | Role of endothelium in responses of vascular smooth muscle. | R F Furchgott | Circ Res | 1983 | 6313250 | No |
953 | 4422 | 2211.0 | 120.04 | 60.0 | A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. | Y Matsumura, H Maeda | Cancer Res | 1986 | 2946403 | Yes |
954 | 4422 | 2211.0 | 96.31 | 48.2 | Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. | F Sallusto, A Lanzavecchia | J Exp Med | 1994 | 8145033 | Yes |
955 | 4419 | 2209.5 | 99.17 | 49.6 | The Bcl-2 protein family: arbiters of cell survival. | J M Adams, S Cory | Science | 1998 | 9735050 | No |
956 | 2207 | 2207.0 | 65.53 | 65.5 | Diagnosis of Alzheimer's disease. | Z S Khachaturian | Arch Neurol | 1985 | 2864910 | Yes |
957 | 4409 | 2204.5 | 99.08 | 49.5 | Brown adipose tissue: function and physiological significance. | Barbara Cannon, Jan Nedergaard | Physiol Rev | 2004 | 14715917 | No |
958 | 2201 | 2201.0 | 52.93 | 52.9 | Lead- and drug-like compounds: the rule-of-five revolution. | Christopher A Lipinski | Drug Discov Today Technol | 2004 | 24981612 | Yes |
959 | 2200 | 2200.0 | 56.03 | 56.0 | Standardized low-resolution brain electromagnetic tomography (sLORETA): technical details. | R D Pascual-Marqui | Methods Find Exp Clin Pharmacol | 2002 | 12575463 | No |
960 | 2199 | 2199.0 | 89.07 | 89.1 | Role of Streptococcus mutans in human dental decay. | W J Loesche | Microbiol Rev | 1986 | 3540569 | No |
961 | 2199 | 2199.0 | 69.11 | 69.1 | Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. | W A Craig | Clin Infect Dis | 1998 | 9455502 | No |
962 | 2198 | 2198.0 | 57.49 | 57.5 | Pancreatic cancer. | Manuel Hidalgo | N Engl J Med | 2010 | 20427809 | No |
963 | 2195 | 2195.0 | 54.9 | 54.9 | Removal of fatty acids from serum albumin by charcoal treatment. | R F Chen | J Biol Chem | 1967 | 6016603 | Yes |
964 | 4388 | 2194.0 | 125.64 | 62.8 | Distributed hierarchical processing in the primate cerebral cortex. | D J Felleman, D C Van Essen | Cereb Cortex | 1991 | 1822724 | No |
965 | 2194 | 2194.0 | 63.83 | 63.8 | Social determinants of health inequalities. | Michael Marmot | Lancet | 2005 | 15781105 | Yes |
966 | 2193 | 2193.0 | 41.32 | 41.3 | Shelterin: the protein complex that shapes and safeguards human telomeres. | Titia de Lange | Genes Dev | 2005 | 16166375 | No |
967 | 2193 | 2193.0 | 61.78 | 61.8 | Hybrid porous solids: past, present, future. | Gérard Férey | Chem Soc Rev | 2008 | 18197340 | Yes |
968 | 2191 | 2191.0 | 79.16 | 79.2 | Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminals. | H W Steinbusch | Neuroscience | 1981 | 7017455 | Yes |
969 | 2190 | 2190.0 | 47.67 | 47.7 | The distribution of secondary growths in cancer of the breast. 1889. | S Paget | Cancer Metastasis Rev | 1989 | 2673568 | No |
970 | 2189 | 2189.0 | 65.53 | 65.5 | PsychoPy--Psychophysics software in Python. | Jonathan W Peirce | J Neurosci Methods | 2007 | 17254636 | Yes |
971 | 2184 | 2184.0 | 48.44 | 48.4 | Chemokines. | B J Rollins | Blood | 1997 | 9242519 | No |
972 | 2184 | 2184.0 | 86.75 | 86.8 | Approximate entropy as a measure of system complexity. | S M Pincus | Proc Natl Acad Sci U S A | 1991 | 11607165 | Yes |
973 | 4367 | 2183.5 | 111.46 | 55.7 | Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. | M Matsuda, R A DeFronzo | Diabetes Care | 1999 | 10480510 | Yes |
974 | 19639 | 2182.1 | 935.21 | 103.9 | Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. | Jacques Ferlay, Isabelle Soerjomataram, Rajesh Dikshit, Sultan Eser, Colin Mathers, Marise Rebelo, Donald Maxwell Parkin, David Forman, Freddie Bray | Int J Cancer | 2015 | 25220842 | Yes |
975 | 2181 | 2181.0 | 46.82 | 46.8 | Complement. First of two parts. | M J Walport | N Engl J Med | 2001 | 11287977 | No |
976 | 2178 | 2178.0 | 53.22 | 53.2 | Breast cancer and hormone-replacement therapy in the Million Women Study. | Valerie Beral | Lancet | 2003 | 12927427 | Yes |
977 | 2176 | 2176.0 | 75.76 | 75.8 | Large-scale brain networks and psychopathology: a unifying triple network model. | Vinod Menon | Trends Cogn Sci | 2011 | 21908230 | No |
978 | 6525 | 2175.0 | 250.9 | 83.6 | Glucose clamp technique: a method for quantifying insulin secretion and resistance. | R A DeFronzo, J D Tobin, R Andres | Am J Physiol | 1979 | 382871 | Yes |
979 | 2173 | 2173.0 | 90.61 | 90.6 | A systematic method for clinical description and classification of personality variants. A proposal. | C R Cloninger | Arch Gen Psychiatry | 1987 | 3579504 | Yes |
980 | 2168 | 2168.0 | 71.62 | 71.6 | A classification of glycosyl hydrolases based on amino acid sequence similarities. | B Henrissat | Biochem J | 1991 | 1747104 | Yes |
981 | 2167 | 2167.0 | 65.75 | 65.8 | Fetal origins of coronary heart disease. | D J Barker | BMJ | 1995 | 7613432 | No |
982 | 2165 | 2165.0 | 53.47 | 53.5 | P-LINCS: A Parallel Linear Constraint Solver for Molecular Simulation. | Berk Hess | J Chem Theory Comput | 2008 | 26619985 | Yes |
983 | 2162 | 2162.0 | 60.08 | 60.1 | Superoxide radical and superoxide dismutases. | I Fridovich | Annu Rev Biochem | 1995 | 7574505 | No |
984 | 2162 | 2162.0 | 70.32 | 70.3 | Keratoconus. | Y S Rabinowitz | Surv Ophthalmol | 1998 | 9493273 | No |
985 | 2161 | 2161.0 | 41.81 | 41.8 | Protein modules and signalling networks. | T Pawson | Nature | 1995 | 7531822 | No |
986 | 2161 | 2161.0 | 58.62 | 58.6 | Biofilms: microbial life on surfaces. | Rodney M Donlan | Emerg Infect Dis | 2002 | 12194761 | No |
987 | 4322 | 2161.0 | 0.0 | 0.0 | Loss of recent memory after bilateral hippocampal lesions. | W B Scoville, B Milner | J Neurol Neurosurg Psychiatry | 1957 | 13406589 | Yes |
988 | 8642 | 2160.5 | 208.91 | 52.2 | Matrix elasticity directs stem cell lineage specification. | Adam J Engler, Shamik Sen, H Lee Sweeney, Dennis E Discher | Cell | 2006 | 16923388 | Yes |
989 | 4317 | 2158.5 | 148.01 | 74.0 | Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method. | R B Devereux, N Reichek | Circulation | 1977 | 138494 | Yes |
990 | 4315 | 2157.5 | 104.49 | 52.2 | Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. | Michael T Lin, M Flint Beal | Nature | 2006 | 17051205 | No |
991 | 2156 | 2156.0 | 58.36 | 58.4 | The episodic buffer: a new component of working memory? | A Baddeley | Trends Cogn Sci | 2000 | 11058819 | Yes |
992 | 2154 | 2154.0 | 31.04 | 31.0 | Sedimentation Studies Of The Size And Shape Of Dna. | F W Studier | J Mol Biol | 1965 | 14290352 | Yes |
993 | 2153 | 2153.0 | 48.14 | 48.1 | A clearer vision for in vivo imaging. | R Weissleder | Nat Biotechnol | 2001 | 11283581 | No |
994 | 6458 | 2152.7 | 131.59 | 43.9 | Immunochemical quantitation of antigens by single radial immunodiffusion. | G Mancini, A O Carbonara, J F Heremans | Immunochemistry | 1965 | 4956917 | Yes |
995 | 2152 | 2152.0 | 49.47 | 49.5 | Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. | G Trinchieri | Annu Rev Immunol | 1995 | 7612223 | No |
996 | 4304 | 2152.0 | 111.74 | 55.9 | ATHENA, ARTEMIS, HEPHAESTUS: data analysis for X-ray absorption spectroscopy using IFEFFIT. | B Ravel, M Newville | J Synchrotron Radiat | 2005 | 15968136 | Yes |
997 | 4300 | 2150.0 | 81.32 | 40.7 | Variations in pattern of pubertal changes in girls. | W A Marshall, J M Tanner | Arch Dis Child | 1969 | 5785179 | Yes |
998 | 2147 | 2147.0 | 54.06 | 54.1 | The extracellular matrix: not just pretty fibrils. | Richard O Hynes | Science | 2009 | 19965464 | No |
999 | 4293 | 2146.5 | 100.76 | 50.4 | Assembly of asparagine-linked oligosaccharides. | R Kornfeld, S Kornfeld | Annu Rev Biochem | 1985 | 3896128 | No |
1000 | 2144 | 2144.0 | 48.82 | 48.8 | Pathways towards and away from Alzheimer's disease. | Mark P Mattson | Nature | 2004 | 15295589 | No |
1001 | 4287 | 2143.5 | 107.32 | 53.7 | Function and activation of NF-kappa B in the immune system. | P A Baeuerle, T Henkel | Annu Rev Immunol | 1994 | 8011280 | No |
1002 | 6429 | 2143.0 | 191.2 | 63.7 | The brain's default network: anatomy, function, and relevance to disease. | Randy L Buckner, Jessica R Andrews-Hanna, Daniel L Schacter | Ann N Y Acad Sci | 2008 | 18400922 | No |
1003 | 4285 | 2142.5 | 102.37 | 51.2 | Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. | Hashem B El-Serag, K Lenhard Rudolph | Gastroenterology | 2007 | 17570226 | No |
1004 | 2142 | 2142.0 | 54.78 | 54.8 | Descending control of pain. | Mark J Millan | Prog Neurobiol | 2002 | 12034378 | No |
1005 | 4283 | 2141.5 | 123.4 | 61.7 | Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. | J S Beckman, W H Koppenol | Am J Physiol | 1996 | 8944624 | No |
1006 | 2141 | 2141.0 | 55.92 | 55.9 | The molecular pathology of Alzheimer's disease. | D J Selkoe | Neuron | 1991 | 1673054 | No |
1007 | 8562 | 2140.5 | 173.83 | 43.5 | WebLogo: a sequence logo generator. | Gavin E Crooks, Gary Hon, John-Marc Chandonia, Steven E Brenner | Genome Res | 2004 | 15173120 | Yes |
1008 | 2140 | 2140.0 | 59.96 | 60.0 | The energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers. | D E Atkinson | Biochemistry | 1968 | 4972613 | Yes |
1009 | 2140 | 2140.0 | 0.0 | 0.0 | Analysis of tissue and arterial blood temperatures in the resting human forearm. | H H Pennes | J Appl Physiol | 1948 | 18887578 | Yes |
1010 | 2137 | 2137.0 | 0.0 | 0.0 | A new specific color reaction of hexuronic acids. | Z Dische | J Biol Chem | 1947 | 20281638 | Yes |
1011 | 6409 | 2136.3 | 185.0 | 61.7 | Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. | C E Murry, R B Jennings, K A Reimer | Circulation | 1986 | 3769170 | Yes |
1012 | 6409 | 2136.3 | 177.68 | 59.2 | Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. | F E Harrell, K L Lee, D B Mark | Stat Med | 1996 | 8668867 | No |
1013 | 4271 | 2135.5 | 73.76 | 36.9 | A Simplified Lead Citrate Stain For Use In Electron Microscopy. | J H Venable, R Coggeshall | J Cell Biol | 1965 | 14287192 | Yes |
1014 | 2132 | 2132.0 | 39.96 | 40.0 | NK cell recognition. | Lewis L Lanier | Annu Rev Immunol | 2005 | 15771571 | No |
1015 | 2125 | 2125.0 | 60.04 | 60.0 | Infrared spectroscopy of proteins. | Andreas Barth | Biochim Biophys Acta | 2007 | 17692815 | No |
1016 | 2124 | 2124.0 | 51.01 | 51.0 | Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences. | Edward V Loftus | Gastroenterology | 2004 | 15168363 | Yes |
1017 | 6367 | 2122.3 | 145.88 | 48.6 | MOLMOL: a program for display and analysis of macromolecular structures. | R Koradi, M Billeter, K Wüthrich | J Mol Graph | 1996 | 8744573 | Yes |
1018 | 2122 | 2122.0 | 90.2 | 90.2 | What's in a name? Qualitative description revisited. | Margarete Sandelowski | Res Nurs Health | 2010 | 20014004 | Yes |
1019 | 4243 | 2121.5 | 121.74 | 60.9 | Angiogenic factors. | J Folkman, M Klagsbrun | Science | 1987 | 2432664 | No |
1020 | 2121 | 2121.0 | 52.52 | 52.5 | Using circular dichroism spectra to estimate protein secondary structure. | Norma J Greenfield | Nat Protoc | 2006 | 17406547 | Yes |
1021 | 6362 | 2120.7 | 198.61 | 66.2 | Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire. | R L Spitzer, K Kroenke, J B Williams | JAMA | 1999 | 10568646 | Yes |
1022 | 2120 | 2120.0 | 42.4 | 42.4 | Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. | Shimon Sakaguchi | Nat Immunol | 2005 | 15785760 | No |
1023 | 6357 | 2119.0 | 282.07 | 94.0 | Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test. | B N Ames, J Mccann, E Yamasaki | Mutat Res | 1975 | 768755 | Yes |
1024 | 2119 | 2119.0 | 48.01 | 48.0 | Comparison of the predicted and observed secondary structure of T4 phage lysozyme. | B W Matthews | Biochim Biophys Acta | 1975 | 1180967 | Yes |
1025 | 2118 | 2118.0 | 44.57 | 44.6 | Mammalian G1 cyclins. | C J Sherr | Cell | 1993 | 8513492 | No |
1026 | 4235 | 2117.5 | 80.52 | 40.3 | The fundamental role of epigenetic events in cancer. | Peter A Jones, Stephen B Baylin | Nat Rev Genet | 2002 | 12042769 | No |
1027 | 2116 | 2116.0 | 35.69 | 35.7 | Methods for the quantitative estimation of N-acetylneuraminic acid and their application to hydrolysates of sialomucoids. | D Aminoff | Biochem J | 1961 | 13860975 | Yes |
1028 | 2115 | 2115.0 | 104.04 | 104.0 | Metazoan MicroRNAs. | David P Bartel | Cell | 2018 | 29570994 | No |
1029 | 6340 | 2113.3 | 119.35 | 39.8 | Control of regulatory T cell development by the transcription factor Foxp3. | Shohei Hori, Takashi Nomura, Shimon Sakaguchi | Science | 2003 | 12522256 | Yes |
1030 | 2113 | 2113.0 | 63.97 | 64.0 | The unbiased estimation of number and sizes of arbitrary particles using the disector. | D C Sterio | J Microsc | 1984 | 6737468 | Yes |
1031 | 4225 | 2112.5 | 180.43 | 90.2 | The Health Belief Model: a decade later. | N K Janz, M H Becker | Health Educ Q | 1984 | 6392204 | No |
1032 | 6321 | 2107.0 | 159.95 | 53.3 | GUS fusions: beta-glucuronidase as a sensitive and versatile gene fusion marker in higher plants. | R A Jefferson, T A Kavanagh, M W Bevan | EMBO J | 1987 | 3327686 | Yes |
1033 | 4214 | 2107.0 | 106.66 | 53.3 | Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. | E Lander, L Kruglyak | Nat Genet | 1995 | 7581446 | Yes |
1034 | 2107 | 2107.0 | 45.11 | 45.1 | Theta oscillations in the hippocampus. | György Buzsáki | Neuron | 2002 | 11832222 | No |
1035 | 2107 | 2107.0 | 42.95 | 43.0 | Role of angiogenesis in tumor growth and metastasis. | Judah Folkman | Semin Oncol | 2002 | 12516034 | No |
1036 | 2105 | 2105.0 | 54.32 | 54.3 | The physiology of glucagon-like peptide 1. | Jens Juul Holst | Physiol Rev | 2007 | 17928588 | No |
1037 | 12628 | 2104.7 | 281.92 | 47.0 | NMRPipe: a multidimensional spectral processing system based on UNIX pipes. | F Delaglio, S Grzesiek, G W Vuister, G Zhu, J Pfeifer, A Bax | J Biomol NMR | 1995 | 8520220 | Yes |
1038 | 4206 | 2103.0 | 134.04 | 67.0 | A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. | Gary J Bennett, Y-K Xie | Pain | 1988 | 2837713 | Yes |
1039 | 2103 | 2103.0 | 61.53 | 61.5 | Hypoxia-inducible factors in physiology and medicine. | Gregg L Semenza | Cell | 2012 | 22304911 | No |
1040 | 2100 | 2100.0 | 49.64 | 49.6 | Patterns of amino acids near signal-sequence cleavage sites. | G von Heijne | Eur J Biochem | 1983 | 6852022 | Yes |
1041 | 2100 | 2100.0 | 52.89 | 52.9 | Accurate description of van der Waals complexes by density functional theory including empirical corrections. | Stefan Grimme | J Comput Chem | 2004 | 15224390 | Yes |
1042 | 2098 | 2098.0 | 112.94 | 112.9 | The assessment of clinical skills/competence/performance. | G E Miller | Acad Med | 1990 | 2400509 | Yes |
1043 | 4196 | 2098.0 | 82.26 | 41.1 | Network biology: understanding the cell's functional organization. | Albert-László Barabási, Zoltán N Oltvai | Nat Rev Genet | 2004 | 14735121 | No |
1044 | 2096 | 2096.0 | 55.28 | 55.3 | The plasma lecithins:cholesterol acyltransferase reaction. | J A Glomset | J Lipid Res | 1968 | 4868699 | No |
1045 | 2095 | 2095.0 | 90.65 | 90.7 | The Children's Depression, Inventory (CDI). | M Kovacs | Psychopharmacol Bull | 1985 | 4089116 | Yes |
1046 | 2095 | 2095.0 | 38.15 | 38.1 | Chemiosmotic coupling in oxidative and photosynthetic phosphorylation. | P Mitchell | Biol Rev Camb Philos Soc | 1966 | 5329743 | No |
1047 | 2092 | 2092.0 | 83.15 | 83.2 | A clinically based classification system for acute pancreatitis. Summary of the International Symposium on Acute Pancreatitis, Atlanta, Ga, September 11 through 13, 1992. | E L Bradley | Arch Surg | 1993 | 8489394 | No |
1048 | 4184 | 2092.0 | 110.34 | 55.2 | The inflammasomes. | Kate Schroder, Jurg Tschopp | Cell | 2010 | 20303873 | No |
1049 | 4182 | 2091.0 | 143.26 | 71.6 | Shifting the genomic gold standard for the prokaryotic species definition. | Michael Richter, Ramon Rosselló-Móra | Proc Natl Acad Sci U S A | 2009 | 19855009 | Yes |
1050 | 4180 | 2090.0 | 82.26 | 41.1 | Smad-dependent and Smad-independent pathways in TGF-beta family signalling. | Rik Derynck, Ying E Zhang | Nature | 2003 | 14534577 | No |
1051 | 2088 | 2088.0 | 103.37 | 103.4 | Abiotic Stress Signaling and Responses in Plants. | Jian-Kang Zhu | Cell | 2016 | 27716505 | No |
1052 | 2087 | 2087.0 | 90.41 | 90.4 | Method For Assay Of Intestinal Disaccharidases. | A Dahlqvist | Anal Biochem | 1964 | 14106916 | Yes |
1053 | 2084 | 2084.0 | 45.64 | 45.6 | Biology of natural killer cells. | G Trinchieri | Adv Immunol | 1989 | 2683611 | No |
1054 | 4166 | 2083.0 | 101.59 | 50.8 | Measuring the thickness of the human cerebral cortex from magnetic resonance images. | B Fischl, A M Dale | Proc Natl Acad Sci U S A | 2000 | 10984517 | Yes |
1055 | 6242 | 2080.7 | 128.24 | 42.7 | EMBOSS: the European Molecular Biology Open Software Suite. | P Rice, I Longden, A Bleasby | Trends Genet | 2000 | 10827456 | Yes |
1056 | 4156 | 2078.0 | 108.71 | 54.4 | The heat-shock proteins. | S Lindquist, E A Craig | Annu Rev Genet | 1988 | 2853609 | No |
1057 | 2078 | 2078.0 | 74.17 | 74.2 | International experiences with the Hospital Anxiety and Depression Scale--a review of validation data and clinical results. | C Herrmann | J Psychosom Res | 1997 | 9055211 | No |
1058 | 6229 | 2076.3 | 146.91 | 49.0 | APE: Analyses of Phylogenetics and Evolution in R language. | Emmanuel Paradis, Julien Claude, Korbinian Strimmer | Bioinformatics | 2004 | 14734327 | Yes |
1059 | 2076 | 2076.0 | 63.61 | 63.6 | Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. | Leonardo Pantoni | Lancet Neurol | 2010 | 20610345 | No |
1060 | 4146 | 2073.0 | 86.74 | 43.4 | A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation. | G Shaw, R Kamen | Cell | 1986 | 3488815 | Yes |
1061 | 4145 | 2072.5 | 100.53 | 50.3 | Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. | G G Glenner, C W Wong | Biochem Biophys Res Commun | 1984 | 6375662 | Yes |
1062 | 2070 | 2070.0 | 38.03 | 38.0 | Enzymatic Basis For Active Transport Of Na+ And K+ Across Cell Membrane. | J C Skou | Physiol Rev | 1965 | 14337569 | No |
1063 | 2069 | 2069.0 | 45.26 | 45.3 | Defensins: antimicrobial peptides of innate immunity. | Tomas Ganz | Nat Rev Immunol | 2003 | 12949495 | No |
1064 | 2069 | 2069.0 | 50.14 | 50.1 | Dopamine, learning and motivation. | Roy A Wise | Nat Rev Neurosci | 2004 | 15152198 | No |
1065 | 4137 | 2068.5 | 82.44 | 41.2 | Mammalian MAP kinase signalling cascades. | L Chang, M Karin | Nature | 2001 | 11242034 | No |
1066 | 8273 | 2068.2 | 303.64 | 75.9 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | J Clin Epidemiol | 2009 | 19631508 | No |
1067 | 4136 | 2068.0 | 36.42 | 18.2 | Genetic regulatory mechanisms in the synthesis of proteins. | F Jacob, J Monod | J Mol Biol | 1961 | 13718526 | Yes |
1068 | 2068 | 2068.0 | 54.21 | 54.2 | Selection Of Hybrids From Matings Of Fibroblasts In Vitro And Their Presumed Recombinants. | J W Littlefield | Science | 1964 | 14168277 | Yes |
1069 | 4135 | 2067.5 | 81.64 | 40.8 | Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. | M Gossen, H Bujard | Proc Natl Acad Sci U S A | 1992 | 1319065 | Yes |
1070 | 2067 | 2067.0 | 59.42 | 59.4 | ATP-regulated K+ channels in cardiac muscle. | A Noma | Nature | 1983 | 6310409 | Yes |
1071 | 2066 | 2066.0 | 42.49 | 42.5 | G1 events and regulation of cell proliferation. | A B Pardee | Science | 1989 | 2683075 | No |
1072 | 2066 | 2066.0 | 53.22 | 53.2 | The heme oxygenase system: a regulator of second messenger gases. | M D Maines | Annu Rev Pharmacol Toxicol | 1997 | 9131263 | No |
1073 | 2059 | 2059.0 | 48.45 | 48.5 | Interleukin-2: inception, impact, and implications. | K A Smith | Science | 1988 | 3131876 | No |
1074 | 2059 | 2059.0 | 68.8 | 68.8 | Purinergic nerves. | G Burnstock | Pharmacol Rev | 1972 | 4404211 | No |
1075 | 2059 | 2059.0 | 48.07 | 48.1 | Metabolomics--the link between genotypes and phenotypes. | Oliver Fiehn | Plant Mol Biol | 2002 | 11860207 | No |
1076 | 2059 | 2059.0 | 67.24 | 67.2 | Optimal caliper widths for propensity-score matching when estimating differences in means and differences in proportions in observational studies. | Peter C Austin | Pharm Stat | 2011 | 20925139 | Yes |
1077 | 4117 | 2058.5 | 0.0 | 0.0 | Plaque formation and isolation of pure lines with poliomyelitis viruses. | R Dulbecco, M Vogt | J Exp Med | 1954 | 13130792 | Yes |
1078 | 2054 | 2054.0 | 50.29 | 50.3 | Drug-like properties and the causes of poor solubility and poor permeability. | C A Lipinski | J Pharmacol Toxicol Methods | 2000 | 11274893 | No |
1079 | 4101 | 2050.5 | 110.83 | 55.4 | New perspectives in cell adhesion: RGD and integrins. | E Ruoslahti, M D Pierschbacher | Science | 1987 | 2821619 | No |
1080 | 4095 | 2047.5 | 80.54 | 40.3 | Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. | Rudolf Jaenisch, Adrian Bird | Nat Genet | 2003 | 12610534 | No |
1081 | 2047 | 2047.0 | 53.11 | 53.1 | Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. | Gökhan S Hotamisligil | Cell | 2010 | 20303879 | No |
1082 | 2046 | 2046.0 | 13.46 | 13.5 | The kinetics of enzyme-catalyzed reactions with two or more substrates or products. I. Nomenclature and rate equations. | W W Cleland | Biochim Biophys Acta | 1963 | 14021667 | Yes |
1083 | 4091 | 2045.5 | 183.6 | 91.8 | Stages and processes of self-change of smoking: toward an integrative model of change. | J O Prochaska, C C DiClemente | J Consult Clin Psychol | 1983 | 6863699 | Yes |
1084 | 8179 | 2044.8 | 175.77 | 43.9 | MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform. | Kazutaka Katoh, Kazuharu Misawa, Kei-ichi Kuma, Takashi Miyata | Nucleic Acids Res | 2002 | 12136088 | Yes |
1085 | 4089 | 2044.5 | 174.19 | 87.1 | The MOS social support survey. | C D Sherbourne, A L Stewart | Soc Sci Med | 1991 | 2035047 | Yes |
1086 | 2044 | 2044.0 | 41.39 | 41.4 | Metastasis to bone: causes, consequences and therapeutic opportunities. | Gregory R Mundy | Nat Rev Cancer | 2002 | 12154351 | No |
1087 | 4082 | 2041.0 | 100.65 | 50.3 | Cutaneous wound healing. | A J Singer, R A Clark | N Engl J Med | 1999 | 10471461 | No |
1088 | 2040 | 2040.0 | 50.45 | 50.5 | Mechanisms of hepatic fibrogenesis. | Scott L Friedman | Gastroenterology | 2008 | 18471545 | No |
1089 | 4079 | 2039.5 | 112.99 | 56.5 | Autophagy: renovation of cells and tissues. | Noboru Mizushima, Masaaki Komatsu | Cell | 2011 | 22078875 | No |
1090 | 2039 | 2039.0 | 58.64 | 58.6 | Medscape's response to the Institute of Medicine Report: Crossing the quality chasm: a new health system for the 21st century. | M Leavitt | MedGenMed | 2001 | 11549951 | No |
1091 | 2038 | 2038.0 | 51.08 | 51.1 | Determination and analysis of urea and guanidine hydrochloride denaturation curves. | C N Pace | Methods Enzymol | 1986 | 3773761 | Yes |
1092 | 6114 | 2038.0 | 182.46 | 60.8 | Arlequin (version 3.0): an integrated software package for population genetics data analysis. | Laurent Excoffier, Guillaume Laval, Stefan Schneider | Evol Bioinform Online | 2007 | 19325852 | Yes |
1093 | 4075 | 2037.5 | 124.86 | 62.4 | Macrophage plasticity and polarization: in vivo veritas. | Antonio Sica, Alberto Mantovani | J Clin Invest | 2012 | 22378047 | No |
1094 | 6111 | 2037.0 | 177.05 | 59.0 | GSVA: gene set variation analysis for microarray and RNA-seq data. | Sonja Hänzelmann, Robert Castelo, Justin Guinney | BMC Bioinformatics | 2013 | 23323831 | Yes |
1095 | 2036 | 2036.0 | 39.53 | 39.5 | Signalling pathways of the TNF superfamily: a double-edged sword. | Bharat B Aggarwal | Nat Rev Immunol | 2003 | 12949498 | No |
1096 | 2035 | 2035.0 | 72.5 | 72.5 | Determination of glutathione and glutathione disulfide in biological samples. | M E Anderson | Methods Enzymol | 1985 | 4088074 | Yes |
1097 | 2035 | 2035.0 | 47.73 | 47.7 | Calcium signaling. | D E Clapham | Cell | 1995 | 7834745 | No |
1098 | 4069 | 2034.5 | 98.55 | 49.3 | Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. | P Liang, A B Pardee | Science | 1992 | 1354393 | Yes |
1099 | 6102 | 2034.0 | 200.83 | 66.9 | Parallel organization of functionally segregated circuits linking basal ganglia and cortex. | G E Alexander, M R DeLong, P L Strick | Annu Rev Neurosci | 1986 | 3085570 | No |
1100 | 2032 | 2032.0 | 56.53 | 56.5 | Estimating causal effects from large data sets using propensity scores. | D B Rubin | Ann Intern Med | 1997 | 9382394 | No |
1101 | 2032 | 2032.0 | 41.86 | 41.9 | Molecular bases for circadian clocks. | J C Dunlap | Cell | 1999 | 9988221 | No |
1102 | 2032 | 2032.0 | 46.69 | 46.7 | Follicular helper CD4 T cells (TFH). | Shane Crotty | Annu Rev Immunol | 2011 | 21314428 | No |
1103 | 8125 | 2031.2 | 266.56 | 66.6 | Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. | A J Hughes, S E Daniel, L Kilford, A J Lees | J Neurol Neurosurg Psychiatry | 1992 | 1564476 | Yes |
1104 | 4061 | 2030.5 | 129.08 | 64.5 | Polymyositis and dermatomyositis (first of two parts). | A Bohan, J B Peter | N Engl J Med | 1975 | 1090839 | No |
1105 | 2030 | 2030.0 | 64.32 | 64.3 | Health consequences of intimate partner violence. | Jacquelyn C Campbell | Lancet | 2002 | 11965295 | No |
1106 | 2028 | 2028.0 | 44.43 | 44.4 | Structural design and molecular evolution of a cytokine receptor superfamily. | J F Bazan | Proc Natl Acad Sci U S A | 1990 | 2169613 | Yes |
1107 | 4049 | 2024.5 | 94.84 | 47.4 | Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. | B A Reynolds, S Weiss | Science | 1992 | 1553558 | Yes |
1108 | 2024 | 2024.0 | 62.82 | 62.8 | Ethical authorship and publishing. | Andrew J S Coats | Int J Cardiol | 2009 | 19046787 | No |
1109 | 4048 | 2024.0 | 118.11 | 59.1 | Wnt/β-catenin signaling and disease. | Hans Clevers, Roel Nusse | Cell | 2012 | 22682243 | No |
1110 | 2022 | 2022.0 | 52.57 | 52.6 | Analysis of bacteriophage T7 early RNAs and proteins on slab gels. | F W Studier | J Mol Biol | 1973 | 4760132 | Yes |
1111 | 2020 | 2020.0 | 0.0 | 0.0 | Antigen-antibody reactions in gels. | O Ouchterlony | Acta Pathol Microbiol Scand | 1949 | 18143039 | Yes |
1112 | 2016 | 2016.0 | 58.45 | 58.5 | Protein oxidation and aging. | E R Stadtman | Science | 1992 | 1355616 | No |
1113 | 6048 | 2016.0 | 186.54 | 62.2 | Universal solvation model based on solute electron density and on a continuum model of the solvent defined by the bulk dielectric constant and atomic surface tensions. | Aleksandr V Marenich, Christopher J Cramer, Donald G Truhlar | J Phys Chem B | 2009 | 19366259 | Yes |
1114 | 2015 | 2015.0 | 39.04 | 39.0 | CpG motifs in bacterial DNA and their immune effects. | Arthur M Krieg | Annu Rev Immunol | 2002 | 11861616 | No |
1115 | 12084 | 2014.0 | 379.29 | 63.2 | Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. | Jacques Ferlay, Hai-Rim Shin, Freddie Bray, David Forman, Colin Mathers, Donald Maxwell Parkin | Int J Cancer | 2010 | 21351269 | Yes |
1116 | 6038 | 2012.7 | 227.32 | 75.8 | Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA. | G Muyzer, E C de Waal, A G Uitterlinden | Appl Environ Microbiol | 1993 | 7683183 | Yes |
1117 | 4025 | 2012.5 | 79.2 | 39.6 | The Wnt signaling pathway in development and disease. | Catriona Y Logan, Roel Nusse | Annu Rev Cell Dev Biol | 2004 | 15473860 | No |
1118 | 6031 | 2010.3 | 193.6 | 64.5 | Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. | C Lord, M Rutter, A Le Couteur | J Autism Dev Disord | 1994 | 7814313 | Yes |
1119 | 2009 | 2009.0 | 35.06 | 35.1 | ATM and related protein kinases: safeguarding genome integrity. | Yosef Shiloh | Nat Rev Cancer | 2003 | 12612651 | No |
1120 | 2007 | 2007.0 | 41.61 | 41.6 | XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density. | D E McRee | J Struct Biol | 1999 | 10222271 | Yes |
1121 | 4009 | 2004.5 | 173.76 | 86.9 | The Brief Symptom Inventory: an introductory report. | L R Derogatis, N Melisaratos | Psychol Med | 1983 | 6622612 | Yes |
1122 | 4008 | 2004.0 | 0.0 | 0.0 | A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. | R F Beers, I W Sizer | J Biol Chem | 1952 | 14938361 | Yes |
1123 | 10020 | 2004.0 | 234.21 | 46.8 | Development and testing of a general amber force field. | Junmei Wang, Romain M Wolf, James W Caldwell, Peter A Kollman, David A Case | J Comput Chem | 2004 | 15116359 | Yes |
1124 | 2004 | 2004.0 | 47.32 | 47.3 | Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. | Scott L Friedman | Physiol Rev | 2008 | 18195085 | No |
1125 | 2002 | 2002.0 | 78.47 | 78.5 | Perception of risk. | P Slovic | Science | 1987 | 3563507 | Yes |
1126 | 2002 | 2002.0 | 46.85 | 46.9 | DAMPs, PAMPs and alarmins: all we need to know about danger. | Marco E Bianchi | J Leukoc Biol | 2007 | 17032697 | No |
1127 | 4003 | 2001.5 | 96.84 | 48.4 | Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions. | M Nei, T Gojobori | Mol Biol Evol | 1986 | 3444411 | Yes |
1128 | 4002 | 2001.0 | 107.66 | 53.8 | The unfolded protein response: from stress pathway to homeostatic regulation. | Peter Walter, David Ron | Science | 2011 | 22116877 | No |
1129 | 8002 | 2000.5 | 380.62 | 95.2 | The Satisfaction With Life Scale. | E Diener, R A Emmons, R J Larsen, S Griffin | J Pers Assess | 1985 | 16367493 | Yes |
1130 | 4000 | 2000.0 | 103.32 | 51.7 | Building better batteries. | M Armand, J-M Tarascon | Nature | 2008 | 18256660 | No |
1131 | 1996 | 1996.0 | 42.49 | 42.5 | The fractionation of high-molecular-weight ribonucleic acid by polyacrylamide-gel electrophoresis. | U E Loening | Biochem J | 1967 | 5339944 | Yes |
1132 | 1994 | 1994.0 | 36.55 | 36.5 | In situ hybridization: an improved whole-mount method for Xenopus embryos. | R M Harland | Methods Cell Biol | 1991 | 1811161 | Yes |
1133 | 1992 | 1992.0 | 50.69 | 50.7 | Flow-mediated endothelial mechanotransduction. | P F Davies | Physiol Rev | 1995 | 7624393 | No |
1134 | 1990 | 1990.0 | 40.92 | 40.9 | Mechanisms of intracellular protein transport. | J E Rothman | Nature | 1994 | 7969419 | No |
1135 | 3980 | 1990.0 | 143.7 | 71.8 | Deciphering key features in protein structures with the new ENDscript server. | Xavier Robert, Patrice Gouet | Nucleic Acids Res | 2014 | 24753421 | Yes |
1136 | 3976 | 1988.0 | 86.12 | 43.1 | The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. | A J Ridley, A Hall | Cell | 1992 | 1643657 | Yes |
1137 | 7948 | 1987.0 | 297.82 | 74.5 | The Fagerström Test for Nicotine Dependence: a revision of the Fagerström Tolerance Questionnaire. | T F Heatherton, L T Kozlowski, R C Frecker, K O Fagerström | Br J Addict | 1991 | 1932883 | Yes |
1138 | 1987 | 1987.0 | 82.68 | 82.7 | A rating scale for drug-induced akathisia. | T R Barnes | Br J Psychiatry | 1989 | 2574607 | Yes |
1139 | 3972 | 1986.0 | 85.27 | 42.6 | Lessons from hereditary colorectal cancer. | K W Kinzler, B Vogelstein | Cell | 1996 | 8861899 | No |
1140 | 1985 | 1985.0 | 72.38 | 72.4 | UCLA Loneliness Scale (Version 3): reliability, validity, and factor structure. | D W Russell | J Pers Assess | 1996 | 8576833 | Yes |
1141 | 1984 | 1984.0 | 95.2 | 95.2 | Performance-oriented assessment of mobility problems in elderly patients. | M E Tinetti | J Am Geriatr Soc | 1986 | 3944402 | Yes |
1142 | 1984 | 1984.0 | 38.49 | 38.5 | Antiviral actions of interferons. | C E Samuel | Clin Microbiol Rev | 2001 | 11585785 | No |
1143 | 1984 | 1984.0 | 55.28 | 55.3 | Japanese Classification of Gastric Carcinoma - 2nd English Edition - | Japanese Gastric Cancer Association | Gastric Cancer | 1998 | 11957040 | Yes |
1144 | 1982 | 1982.0 | 52.99 | 53.0 | Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis. | J Folkman | N Engl J Med | 1995 | 7491141 | No |
1145 | 1981 | 1981.0 | 54.42 | 54.4 | The biology of interleukin-6. | T Kishimoto | Blood | 1989 | 2473791 | No |
1146 | 1981 | 1981.0 | 20.62 | 20.6 | Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? | J V Neel | Am J Hum Genet | 1962 | 13937884 | Yes |
1147 | 1980 | 1980.0 | 39.3 | 39.3 | DNA topoisomerases: structure, function, and mechanism. | J J Champoux | Annu Rev Biochem | 2001 | 11395412 | No |
1148 | 1978 | 1978.0 | 48.12 | 48.1 | Interfaces and the driving force of hydrophobic assembly. | David Chandler | Nature | 2005 | 16193038 | No |
1149 | 1975 | 1975.0 | 65.75 | 65.8 | The use of a plus-maze to measure anxiety in the mouse. | R G Lister | Psychopharmacology (Berl) | 1987 | 3110839 | Yes |
1150 | 3944 | 1972.0 | 97.74 | 48.9 | Leptin and the regulation of body weight in mammals. | J M Friedman, J L Halaas | Nature | 1998 | 9796811 | No |
1151 | 3943 | 1971.5 | 89.89 | 44.9 | The acute respiratory distress syndrome. | L B Ware, M A Matthay | N Engl J Med | 2000 | 10793167 | No |
1152 | 1970 | 1970.0 | 50.42 | 50.4 | What is cognitive reserve? Theory and research application of the reserve concept. | Yaakov Stern | J Int Neuropsychol Soc | 2002 | 11939702 | No |
1153 | 3939 | 1969.5 | 90.18 | 45.1 | Base-calling of automated sequencer traces using phred. II. Error probabilities. | B Ewing, P Green | Genome Res | 1998 | 9521922 | Yes |
1154 | 1968 | 1968.0 | 58.05 | 58.0 | Intracellular calcium homeostasis. | E Carafoli | Annu Rev Biochem | 1987 | 3304139 | No |
1155 | 1968 | 1968.0 | 48.58 | 48.6 | Negative refraction makes a perfect lens | J B Pendry | Phys Rev Lett | 2000 | 11041972 | Yes |
1156 | 1968 | 1968.0 | 41.65 | 41.6 | Developmental regulation of the growth plate. | Henry M Kronenberg | Nature | 2003 | 12748651 | No |
1157 | 1968 | 1968.0 | 41.45 | 41.5 | TRP channels as cellular sensors. | David E Clapham | Nature | 2003 | 14654832 | No |
1158 | 1968 | 1968.0 | 58.83 | 58.8 | Global epidemiology of oral and oropharyngeal cancer. | Saman Warnakulasuriya | Oral Oncol | 2009 | 18804401 | No |
1159 | 13774 | 1967.7 | 304.07 | 43.4 | Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. | Jo Vandesompele, Katleen De Preter, Filip Pattyn, Bruce Poppe, Nadine Van Roy, Anne De Paepe, Frank Speleman | Genome Biol | 2002 | 12184808 | Yes |
1160 | 1964 | 1964.0 | 86.43 | 86.4 | A modified card sorting test sensitive to frontal lobe defects. | H E Nelson | Cortex | 1976 | 1009768 | Yes |
1161 | 3926 | 1963.0 | 107.63 | 53.8 | Insulin-like growth factors and their binding proteins: biological actions. | J I Jones, D R Clemmons | Endocr Rev | 1995 | 7758431 | No |
1162 | 1963 | 1963.0 | 35.02 | 35.0 | Signaling--2000 and beyond. | T Hunter | Cell | 2000 | 10647936 | No |
1163 | 3924 | 1962.0 | 96.69 | 48.3 | Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. | P J Barnes, M Karin | N Engl J Med | 1997 | 9091804 | No |
1164 | 1962 | 1962.0 | 55.07 | 55.1 | Flavonoids as antioxidants. | P G Pietta | J Nat Prod | 2000 | 10924197 | No |
1165 | 3924 | 1962.0 | 74.72 | 37.4 | SIFT: Predicting amino acid changes that affect protein function. | Pauline C Ng, Steven Henikoff | Nucleic Acids Res | 2003 | 12824425 | Yes |
1166 | 1962 | 1962.0 | 42.81 | 42.8 | Neutrophils and immunity: challenges and opportunities. | Carl Nathan | Nat Rev Immunol | 2006 | 16498448 | No |
1167 | 1960 | 1960.0 | 90.91 | 90.9 | The brain's default mode network. | Marcus E Raichle | Annu Rev Neurosci | 2015 | 25938726 | No |
1168 | 1957 | 1957.0 | 38.18 | 38.2 | Approaching the asymptote? Evolution and revolution in immunology. | C A Janeway | Cold Spring Harb Symp Quant Biol | 1989 | 2700931 | No |
1169 | 1956 | 1956.0 | 0.0 | 0.0 | Crystalline Soybean Trypsin Inhibitor : Ii. General Properties. | M Kunitz | J Gen Physiol | 1947 | 19873496 | Yes |
1170 | 3911 | 1955.5 | 65.48 | 32.7 | Periodate-lysine-paraformaldehyde fixative. A new fixation for immunoelectron microscopy. | I W McLean, P K Nakane | J Histochem Cytochem | 1974 | 4374474 | Yes |
1171 | 3908 | 1954.0 | 123.6 | 61.8 | Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid. | A C Chang, S N Cohen | J Bacteriol | 1978 | 149110 | Yes |
1172 | 5860 | 1953.3 | 120.56 | 40.2 | Rapid and efficient site-specific mutagenesis without phenotypic selection. | T A Kunkel, J D Roberts, R A Zakour | Methods Enzymol | 1987 | 3323813 | Yes |
1173 | 31241 | 1952.6 | 1017.79 | 63.6 | Fiji: an open-source platform for biological-image analysis. | Johannes Schindelin, Ignacio Arganda-Carreras, Erwin Frise, Verena Kaynig, Mark Longair, Tobias Pietzsch, Stephan Preibisch, Curtis Rueden, Stephan Saalfeld, Benjamin Schmid, Jean-Yves Tinevez, Daniel James White, Volker Hartenstein, Kevin Eliceiri, Pavel Tomancak, Albert Cardona | Nat Methods | 2012 | 22743772 | Yes |
1174 | 1952 | 1952.0 | 0.0 | 0.0 | On estimating the relation between blood group and disease. | B Woolf | Ann Hum Genet | 1955 | 14388528 | Yes |
1175 | 3902 | 1951.0 | 109.01 | 54.5 | Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. | B J Marshall, J R Warren | Lancet | 1984 | 6145023 | Yes |
1176 | 1951 | 1951.0 | 0.0 | 0.0 | The adsorption of proteins on erythrocytes treated with tannic acid and subsequent hemagglutination by antiprotein sera. | S V Boyden | J Exp Med | 1951 | 14803635 | Yes |
1177 | 7802 | 1950.5 | 232.39 | 58.1 | Antibiotic susceptibility testing by a standardized single disk method. | A W Bauer, W M Kirby, J C Sherris, M Turck | Am J Clin Pathol | 1966 | 5325707 | Yes |
1178 | 1950 | 1950.0 | 79.51 | 79.5 | Specific pharmacology of calcium in myocardium, cardiac pacemakers, and vascular smooth muscle. | A Fleckenstein | Annu Rev Pharmacol Toxicol | 1977 | 326161 | No |
1179 | 1950 | 1950.0 | 69.28 | 69.3 | The emerging role of lncRNAs in cancer. | Maite Huarte | Nat Med | 2015 | 26540387 | No |
1180 | 7799 | 1949.8 | 324.07 | 81.0 | jModelTest 2: more models, new heuristics and parallel computing. | Diego Darriba, Guillermo L Taboada, Ramón Doallo, David Posada | Nat Methods | 2012 | 22847109 | Yes |
1181 | 1948 | 1948.0 | 60.25 | 60.2 | Fluorographic detection of radioactivity in polyacrylamide gels with the water-soluble fluor, sodium salicylate. | J P Chamberlain | Anal Biochem | 1979 | 543547 | Yes |
1182 | 1948 | 1948.0 | 0.0 | 0.0 | Influences of glucose loading and of injected insulin on hepatic glucose output. | R Steele | Ann N Y Acad Sci | 1959 | 13833973 | Yes |
1183 | 1947 | 1947.0 | 58.76 | 58.8 | Loss, trauma, and human resilience: have we underestimated the human capacity to thrive after extremely aversive events? | George A Bonanno | Am Psychol | 2004 | 14736317 | No |
1184 | 1947 | 1947.0 | 53.66 | 53.7 | Trail Making Test A and B: normative data stratified by age and education. | Tom N Tombaugh | Arch Clin Neuropsychol | 2004 | 15010086 | Yes |
1185 | 1947 | 1947.0 | 38.54 | 38.5 | DNA methylation and human disease. | Keith D Robertson | Nat Rev Genet | 2005 | 16136652 | No |
1186 | 3894 | 1947.0 | 115.2 | 57.6 | Oncology meets immunology: the cancer-immunity cycle. | Daniel S Chen, Ira Mellman | Immunity | 2013 | 23890059 | No |
1187 | 1946 | 1946.0 | 64.2 | 64.2 | Intermediate filaments as mechanical integrators of cellular space. | E Lazarides | Nature | 1980 | 7188712 | Yes |
1188 | 5838 | 1946.0 | 189.69 | 63.2 | AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. | P G Reeves, F H Nielsen, G C Fahey | J Nutr | 1993 | 8229312 | No |
1189 | 1944 | 1944.0 | 37.75 | 37.8 | Systems biology: a brief overview. | Hiroaki Kitano | Science | 2002 | 11872829 | No |
1190 | 1942 | 1942.0 | 45.79 | 45.8 | Thickness, cross-sectional areas and depth of invasion in the prognosis of cutaneous melanoma. | A Breslow | Ann Surg | 1970 | 5477666 | Yes |
1191 | 1942 | 1942.0 | 40.95 | 41.0 | The immunopathogenesis of sepsis. | Jonathan Cohen | Nature | 2002 | 12490963 | No |
1192 | 13591 | 1941.6 | 311.51 | 44.5 | Induction of pluripotent stem cells from adult human fibroblasts by defined factors. | Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda, Shinya Yamanaka | Cell | 2007 | 18035408 | Yes |
1193 | 7763 | 1940.8 | 190.15 | 47.5 | Cancer-related inflammation. | Alberto Mantovani, Paola Allavena, Antonio Sica, Frances Balkwill | Nature | 2008 | 18650914 | No |
1194 | 3878 | 1939.0 | 94.27 | 47.1 | Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. | J G Rheinwald, H Green | Cell | 1975 | 1052771 | Yes |
1195 | 1939 | 1939.0 | 0.0 | 0.0 | On respiratory impairment in cancer cells. | O Warburg | Science | 1956 | 13351639 | Yes |
1196 | 7753 | 1938.2 | 2266.45 | 566.6 | Cancer statistics, 2022. | Rebecca L Siegel, Kimberly D Miller, Hannah E Fuchs, Ahmedin Jemal | CA Cancer J Clin | 2022 | 35020204 | Yes |
1197 | 1938 | 1938.0 | 55.32 | 55.3 | Excitotoxic cell death. | D W Choi | J Neurobiol | 1992 | 1361523 | No |
1198 | 1937 | 1937.0 | 61.33 | 61.3 | Calculation of substrate oxidation rates in vivo from gaseous exchange. | K N Frayn | J Appl Physiol Respir Environ Exerc Physiol | 1983 | 6618956 | Yes |
1199 | 5811 | 1937.0 | 107.55 | 35.9 | Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. | Jason D Fontenot, Marc A Gavin, Alexander Y Rudensky | Nat Immunol | 2003 | 12612578 | Yes |
1200 | 3874 | 1937.0 | 133.0 | 66.5 | Preparation Of Fatty Acid Methyl Esters And Dimethylacetals From Lipids With Boron Fluoride--Methanol. | W R Morrison, L M Smith | J Lipid Res | 1964 | 14221106 | Yes |
1201 | 5808 | 1936.0 | 175.64 | 58.5 | Estimating the mean and variance from the median, range, and the size of a sample. | Stela Pudar Hozo, Benjamin Djulbegovic, Iztok Hozo | BMC Med Res Methodol | 2005 | 15840177 | Yes |
1202 | 1936 | 1936.0 | 45.49 | 45.5 | The global health burden of infection-associated cancers in the year 2002. | Donald Maxwell Parkin | Int J Cancer | 2006 | 16404738 | Yes |
1203 | 1936 | 1936.0 | 39.03 | 39.0 | The complex language of chromatin regulation during transcription. | Shelley L Berger | Nature | 2007 | 17522673 | No |
1204 | 1935 | 1935.0 | 40.38 | 40.4 | A cell culture model for T lymphocyte clonal anergy. | R H Schwartz | Science | 1990 | 2113314 | Yes |
1205 | 3869 | 1934.5 | 88.0 | 44.0 | Liver fibrosis. | Ramón Bataller, David A Brenner | J Clin Invest | 2005 | 15690074 | No |
1206 | 1934 | 1934.0 | 60.95 | 61.0 | Sick individuals and sick populations. | G Rose | Int J Epidemiol | 1985 | 3872850 | Yes |
1207 | 1934 | 1934.0 | 62.68 | 62.7 | Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. | Sergio Pecorelli | Int J Gynaecol Obstet | 2009 | 19367689 | No |
1208 | 3867 | 1933.5 | 85.81 | 42.9 | Issues and challenges facing rechargeable lithium batteries. | J M Tarascon, M Armand | Nature | 2001 | 11713543 | Yes |
1209 | 1932 | 1932.0 | 60.65 | 60.6 | Epidemiological features of chronic low-back pain. | G B Andersson | Lancet | 1999 | 10470716 | No |
1210 | 1932 | 1932.0 | 39.76 | 39.8 | Thrombin signalling and protease-activated receptors. | S R Coughlin | Nature | 2000 | 11001069 | No |
1211 | 1932 | 1932.0 | 44.75 | 44.8 | Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. | B L Wajchenberg | Endocr Rev | 2000 | 11133069 | No |
1212 | 1932 | 1932.0 | 53.17 | 53.2 | Determination of minimum inhibitory concentrations. | J M Andrews | J Antimicrob Chemother | 2001 | 11420333 | Yes |
1213 | 1931 | 1931.0 | 57.41 | 57.4 | Calbindin D-28k and parvalbumin in the rat nervous system. | M R Celio | Neuroscience | 1990 | 2199841 | Yes |
1214 | 3862 | 1931.0 | 86.26 | 43.1 | The DNA-damage response in human biology and disease. | Stephen P Jackson, Jiri Bartek | Nature | 2009 | 19847258 | No |
1215 | 3861 | 1930.5 | 102.57 | 51.3 | Inositol phosphates and cell signalling. | M J Berridge, R F Irvine | Nature | 1989 | 2550825 | No |
1216 | 1929 | 1929.0 | 50.46 | 50.5 | DNA topoisomerase poisons as antitumor drugs. | L F Liu | Annu Rev Biochem | 1989 | 2549853 | No |
1217 | 1929 | 1929.0 | 42.91 | 42.9 | Signal sequences. The limits of variation. | G von Heijne | J Mol Biol | 1985 | 4032478 | Yes |
1218 | 1926 | 1926.0 | 33.89 | 33.9 | Mechanisms of alternative pre-messenger RNA splicing. | Douglas L Black | Annu Rev Biochem | 2003 | 12626338 | No |
1219 | 3849 | 1924.5 | 94.91 | 47.5 | The endophenotype concept in psychiatry: etymology and strategic intentions. | Irving I Gottesman, Todd D Gould | Am J Psychiatry | 2003 | 12668349 | No |
1220 | 3847 | 1923.5 | 123.52 | 61.8 | Oxygen toxicity, oxygen radicals, transition metals and disease. | B Halliwell, J M Gutteridge | Biochem J | 1984 | 6326753 | No |
1221 | 1922 | 1922.0 | 46.94 | 46.9 | DNA topoisomerases. | J C Wang | Annu Rev Biochem | 1985 | 2992360 | No |
1222 | 1922 | 1922.0 | 39.2 | 39.2 | The expanding role of mitochondria in apoptosis. | X Wang | Genes Dev | 2001 | 11711427 | No |
1223 | 3842 | 1921.0 | 73.65 | 36.8 | Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. | M Karin, Y Ben-Neriah | Annu Rev Immunol | 2000 | 10837071 | No |
1224 | 1919 | 1919.0 | 46.53 | 46.5 | Thioredoxin. | A Holmgren | Annu Rev Biochem | 1985 | 3896121 | No |
1225 | 1919 | 1919.0 | 83.05 | 83.0 | Brain dopamine receptors. | P Seeman | Pharmacol Rev | 1980 | 6117090 | No |
1226 | 3832 | 1916.0 | 128.28 | 64.1 | Mathematical model for studying genetic variation in terms of restriction endonucleases. | M Nei, W H Li | Proc Natl Acad Sci U S A | 1979 | 291943 | Yes |
1227 | 1915 | 1915.0 | 33.82 | 33.8 | The regulation of E2F by pRB-family proteins. | N Dyson | Genes Dev | 1998 | 9694791 | No |
1228 | 7656 | 1914.0 | 188.91 | 47.2 | p53 mutations in human cancers. | M Hollstein, D Sidransky, B Vogelstein, C C Harris | Science | 1991 | 1905840 | No |
1229 | 1913 | 1913.0 | 40.78 | 40.8 | The etiology of chondromalacia patellae. | R E Outerbridge | J Bone Joint Surg Br | 1961 | 14038135 | Yes |
1230 | 1913 | 1913.0 | 36.58 | 36.6 | Notch signalling: a simple pathway becomes complex. | Sarah J Bray | Nat Rev Mol Cell Biol | 2006 | 16921404 | No |
1231 | 1912 | 1912.0 | 53.82 | 53.8 | Introduction and General Overview of Cyclodextrin Chemistry. | József Szejtli | Chem Rev | 1998 | 11848947 | Yes |
1232 | 3824 | 1912.0 | 0.0 | 0.0 | Acetylornithinase of Escherichia coli: partial purification and some properties. | H J Vogel, D M Bonner | J Biol Chem | 1956 | 13278318 | Yes |
1233 | 1911 | 1911.0 | 56.07 | 56.1 | Inhibited spontaneous emission in solid-state physics and electronics. | E Yablonovitch | Phys Rev Lett | 1987 | 10034639 | Yes |
1234 | 1910 | 1910.0 | 63.02 | 63.0 | Physiological actions of taurine. | R J Huxtable | Physiol Rev | 1992 | 1731369 | No |
1235 | 1910 | 1910.0 | 42.86 | 42.9 | High-speed scanning in human memory. | S Sternberg | Science | 1966 | 5939936 | Yes |
1236 | 1910 | 1910.0 | 45.32 | 45.3 | The dawning era of polymer therapeutics. | Ruth Duncan | Nat Rev Drug Discov | 2003 | 12750738 | No |
1237 | 1910 | 1910.0 | 59.73 | 59.7 | A new automated colorimetric method for measuring total oxidant status. | Ozcan Erel | Clin Biochem | 2005 | 16214125 | Yes |
1238 | 7638 | 1909.5 | 297.56 | 74.4 | A simple technique for quantitation of low levels of DNA damage in individual cells. | N P Singh, M T McCoy, R R Tice, E L Schneider | Exp Cell Res | 1988 | 3345800 | Yes |
1239 | 1908 | 1908.0 | 46.16 | 46.2 | Cancer chemoprevention with dietary phytochemicals. | Young-Joon Surh | Nat Rev Cancer | 2003 | 14570043 | No |
1240 | 3814 | 1907.0 | 112.58 | 56.3 | Mechanisms of salinity tolerance. | Rana Munns, Mark Tester | Annu Rev Plant Biol | 2008 | 18444910 | No |
1241 | 5718 | 1906.0 | 187.8 | 62.6 | Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction data. | L Excoffier, P E Smouse, J M Quattro | Genetics | 1992 | 1644282 | Yes |
1242 | 1906 | 1906.0 | 39.11 | 39.1 | Mechanisms of cancer drug resistance. | Michael M Gottesman | Annu Rev Med | 2002 | 11818492 | No |
1243 | 1906 | 1906.0 | 61.02 | 61.0 | Grounded cognition. | Lawrence W Barsalou | Annu Rev Psychol | 2008 | 17705682 | No |
1244 | 3811 | 1905.5 | 98.41 | 49.2 | Probing Single Molecules and Single Nanoparticles by Surface-Enhanced Raman Scattering | S Nie, S R Emory | Science | 1997 | 9027306 | Yes |
1245 | 3811 | 1905.5 | 119.26 | 59.6 | Efficient pseudopotentials for plane-wave calculations. | N Troullier, J L Martins | Phys Rev B Condens Matter | 1991 | 9997467 | Yes |
1246 | 1905 | 1905.0 | 41.37 | 41.4 | A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics. | J SantaLucia | Proc Natl Acad Sci U S A | 1998 | 9465037 | Yes |
1247 | 1904 | 1904.0 | 48.98 | 49.0 | Dengue and dengue hemorrhagic fever. | D J Gubler | Clin Microbiol Rev | 1998 | 9665979 | No |
1248 | 1903 | 1903.0 | 54.43 | 54.4 | The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. | G P Chrousos | N Engl J Med | 1995 | 7715646 | No |
1249 | 1902 | 1902.0 | 62.35 | 62.4 | The molecular theory of polyelectrolyte solutions with applications to the electrostatic properties of polynucleotides. | G S Manning | Q Rev Biophys | 1978 | 353876 | No |
1250 | 3802 | 1901.0 | 135.59 | 67.8 | ITS primers with enhanced specificity for basidiomycetes--application to the identification of mycorrhizae and rusts. | M Gardes, T D Bruns | Mol Ecol | 1993 | 8180733 | Yes |
1251 | 5700 | 1900.0 | 337.08 | 112.4 | Research diagnostic criteria: rationale and reliability. | R L Spitzer, J Endicott, E Robins | Arch Gen Psychiatry | 1978 | 655775 | Yes |
1252 | 1900 | 1900.0 | 45.84 | 45.8 | Python: a programming language for software integration and development. | M F Sanner | J Mol Graph Model | 1999 | 10660911 | Yes |
1253 | 1900 | 1900.0 | 0.0 | 0.0 | The oxidation of ribonuclease with performic acid. | C H Hirs | J Biol Chem | 1956 | 13319283 | Yes |
1254 | 1899 | 1899.0 | 53.94 | 53.9 | In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain. | T R Chen | Exp Cell Res | 1977 | 65285 | Yes |
1255 | 3797 | 1898.5 | 133.52 | 66.8 | Reactive oxygen species and antioxidant machinery in abiotic stress tolerance in crop plants. | Sarvajeet Singh Gill, Narendra Tuteja | Plant Physiol Biochem | 2010 | 20870416 | No |
1256 | 1898 | 1898.0 | 24.76 | 24.8 | A theory of cerebellar cortex. | D Marr | J Physiol | 1969 | 5784296 | Yes |
1257 | 1898 | 1898.0 | 46.09 | 46.1 | Episodic memory: from mind to brain. | Endel Tulving | Annu Rev Psychol | 2002 | 11752477 | Yes |
1258 | 1897 | 1897.0 | 47.06 | 47.1 | Pathogen recognition and inflammatory signaling in innate immune defenses. | Trine H Mogensen | Clin Microbiol Rev | 2009 | 19366914 | No |
1259 | 1897 | 1897.0 | 69.73 | 69.7 | Pro-resolving lipid mediators are leads for resolution physiology. | Charles N Serhan | Nature | 2014 | 24899309 | No |
1260 | 20854 | 1895.8 | 520.57 | 47.3 | PLINK: a tool set for whole-genome association and population-based linkage analyses. | Shaun Purcell, Benjamin Neale, Kathe Todd-Brown, Lori Thomas, Manuel A R Ferreira, David Bender, Julian Maller, Pamela Sklar, Paul I W de Bakker, Mark J Daly, Pak C Sham | Am J Hum Genet | 2007 | 17701901 | Yes |
1261 | 3788 | 1894.0 | 88.89 | 44.4 | Neuronal oscillations in cortical networks. | György Buzsáki, Andreas Draguhn | Science | 2004 | 15218136 | No |
1262 | 1893 | 1893.0 | 43.27 | 43.3 | Targeting PI3K signalling in cancer: opportunities, challenges and limitations. | Jeffrey A Engelman | Nat Rev Cancer | 2009 | 19629070 | No |
1263 | 3784 | 1892.0 | 112.27 | 56.1 | Individual differences in two emotion regulation processes: implications for affect, relationships, and well-being. | James J Gross, Oliver P John | J Pers Soc Psychol | 2003 | 12916575 | Yes |
1264 | 1891 | 1891.0 | 41.02 | 41.0 | The mitogen-activated protein kinase signal transduction pathway. | R J Davis | J Biol Chem | 1993 | 8325833 | No |
1265 | 3781 | 1890.5 | 86.4 | 43.2 | The Fas death factor. | S Nagata, P Golstein | Science | 1995 | 7533326 | No |
1266 | 1889 | 1889.0 | 17.5 | 17.5 | Positional information and the spatial pattern of cellular differentiation. | L Wolpert | J Theor Biol | 1969 | 4390734 | Yes |
1267 | 3778 | 1889.0 | 128.76 | 64.4 | Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. | M H Zweig, G Campbell | Clin Chem | 1993 | 8472349 | No |
1268 | 3777 | 1888.5 | 84.25 | 42.1 | Parkinson's disease: mechanisms and models. | William Dauer, Serge Przedborski | Neuron | 2003 | 12971891 | No |
1269 | 1888 | 1888.0 | 59.52 | 59.5 | Complete nucleotide sequence of the Escherichia coli plasmid pBR322. | J G Sutcliffe | Cold Spring Harb Symp Quant Biol | 1979 | 383387 | Yes |
1270 | 3776 | 1888.0 | 84.85 | 42.4 | Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. | T Miyashita, J C Reed | Cell | 1995 | 7834749 | Yes |
1271 | 3775 | 1887.5 | 87.24 | 43.6 | PRODRG: a tool for high-throughput crystallography of protein-ligand complexes. | Alexander W Schüttelkopf, Daan M F van Aalten | Acta Crystallogr D Biol Crystallogr | 2004 | 15272157 | Yes |
1272 | 3770 | 1885.0 | 112.08 | 56.0 | An efficient mRNA-dependent translation system from reticulocyte lysates. | H R Pelham, R J Jackson | Eur J Biochem | 1976 | 823012 | Yes |
1273 | 1884 | 1884.0 | 0.0 | 0.0 | Dendritic organization in the neurons of the visual and motor cortices of the cat. | D A Sholl | J Anat | 1953 | 13117757 | Yes |
1274 | 1884 | 1884.0 | 59.19 | 59.2 | Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders. | Berislav V Zlokovic | Nat Rev Neurosci | 2011 | 22048062 | No |
1275 | 3765 | 1882.5 | 89.73 | 44.9 | The future of genetic studies of complex human diseases. | N Risch, K Merikangas | Science | 1996 | 8801636 | Yes |
1276 | 1881 | 1881.0 | 64.08 | 64.1 | Guided Search 2.0 A revised model of visual search. | J M Wolfe | Psychon Bull Rev | 1994 | 24203471 | Yes |
1277 | 11279 | 1879.8 | 622.32 | 103.7 | DADA2: High-resolution sample inference from Illumina amplicon data. | Benjamin J Callahan, Paul J McMurdie, Michael J Rosen, Andrew W Han, Amy Jo A Johnson, Susan P Holmes | Nat Methods | 2016 | 27214047 | Yes |
1278 | 1879 | 1879.0 | 45.13 | 45.1 | The genetics of ageing. | Cynthia J Kenyon | Nature | 2010 | 20336132 | No |
1279 | 1878 | 1878.0 | 52.94 | 52.9 | Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis. | A Dunaif | Endocr Rev | 1997 | 9408743 | No |
1280 | 5633 | 1877.7 | 243.57 | 81.2 | Scoping studies: advancing the methodology. | Danielle Levac, Heather Colquhoun, Kelly K O'Brien | Implement Sci | 2010 | 20854677 | Yes |
1281 | 5632 | 1877.3 | 144.13 | 48.0 | Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. | G S Hotamisligil, N S Shargill, B M Spiegelman | Science | 1993 | 7678183 | Yes |
1282 | 3754 | 1877.0 | 126.7 | 63.4 | Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. | G Di Chiara, A Imperato | Proc Natl Acad Sci U S A | 1988 | 2899326 | Yes |
1283 | 1876 | 1876.0 | 86.75 | 86.8 | A simple fluorometric assay for lipoperoxide in blood plasma. | K Yagi | Biochem Med | 1976 | 962904 | Yes |
1284 | 1876 | 1876.0 | 41.27 | 41.3 | Cellular mechanisms of insulin resistance. | G I Shulman | J Clin Invest | 2000 | 10903330 | No |
1285 | 1875 | 1875.0 | 41.82 | 41.8 | The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. | Michael R Lieber | Annu Rev Biochem | 2010 | 20192759 | No |
1286 | 1874 | 1874.0 | 69.23 | 69.2 | Recognition-by-components: a theory of human image understanding. | Irving Biederman | Psychol Rev | 1987 | 3575582 | Yes |
1287 | 7494 | 1873.5 | 251.96 | 63.0 | Reporting results of cancer treatment. | A B Miller, B Hoogstraten, M Staquet, A Winkler | Cancer | 1981 | 7459811 | Yes |
1288 | 7493 | 1873.2 | 184.47 | 46.1 | Epithelial-mesenchymal transitions in development and disease. | Jean Paul Thiery, Hervé Acloque, Ruby Y J Huang, M Angela Nieto | Cell | 2009 | 19945376 | No |
1289 | 1872 | 1872.0 | 50.86 | 50.9 | A computational procedure for determining energetically favorable binding sites on biologically important macromolecules. | P J Goodford | J Med Chem | 1985 | 3892003 | Yes |
1290 | 1872 | 1872.0 | 52.03 | 52.0 | Cell biology and molecular basis of denitrification. | W G Zumft | Microbiol Mol Biol Rev | 1997 | 9409151 | No |
1291 | 1869 | 1869.0 | 40.24 | 40.2 | Exploring complex networks. | S H Strogatz | Nature | 2001 | 11258382 | No |
1292 | 1868 | 1868.0 | 53.55 | 53.5 | Multiple imputation: a primer. | J L Schafer | Stat Methods Med Res | 1999 | 10347857 | No |
1293 | 3736 | 1868.0 | 105.81 | 52.9 | Event-related EEG/MEG synchronization and desynchronization: basic principles. | G Pfurtscheller, F H Lopes da Silva | Clin Neurophysiol | 1999 | 10576479 | No |
1294 | 3735 | 1867.5 | 79.11 | 39.6 | Raster3D: photorealistic molecular graphics. | E A Merritt, D J Bacon | Methods Enzymol | 1997 | 18488322 | Yes |
1295 | 1867 | 1867.0 | 45.2 | 45.2 | The hydrogen bond in the solid state. | Thomas Steiner | Angew Chem Int Ed Engl | 2002 | 12491444 | Yes |
1296 | 1866 | 1866.0 | 114.45 | 114.5 | Understanding Bland Altman analysis. | Davide Giavarina | Biochem Med (Zagreb) | 2015 | 26110027 | No |
1297 | 5590 | 1863.3 | 125.95 | 42.0 | A new statistical method for haplotype reconstruction from population data. | M Stephens, N J Smith, P Donnelly | Am J Hum Genet | 2001 | 11254454 | Yes |
1298 | 3725 | 1862.5 | 68.03 | 34.0 | Rho GTPases in cell biology. | Sandrine Etienne-Manneville, Alan Hall | Nature | 2002 | 12478284 | No |
1299 | 1861 | 1861.0 | 68.09 | 68.1 | Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury. | D R Janero | Free Radic Biol Med | 1990 | 2079232 | No |
1300 | 14885 | 1860.6 | 364.85 | 45.6 | Electric field effect in atomically thin carbon films. | K S Novoselov, A K Geim, S V Morozov, D Jiang, Y Zhang, S V Dubonos, I V Grigorieva, A A Firsov | Science | 2004 | 15499015 | Yes |
1301 | 13011 | 1858.7 | 464.42 | 66.3 | Assessing the quality of reports of randomized clinical trials: is blinding necessary? | A R Jadad, R A Moore, D Carroll, C Jenkinson, D J Reynolds, D J Gavaghan, H J McQuay | Control Clin Trials | 1996 | 8721797 | Yes |
1302 | 1858 | 1858.0 | 53.8 | 53.8 | Molecular weight determination of protein-dodecyl sulfate complexes by gel electrophoresis in a discontinuous buffer system. | D M Neville | J Biol Chem | 1971 | 5127429 | Yes |
1303 | 1857 | 1857.0 | 41.6 | 41.6 | Fabrication of novel biomaterials through molecular self-assembly. | Shuguang Zhang | Nat Biotechnol | 2003 | 14520402 | No |
1304 | 3714 | 1857.0 | 116.88 | 58.4 | Understanding interobserver agreement: the kappa statistic. | Anthony J Viera, Joanne M Garrett | Fam Med | 2005 | 15883903 | Yes |
1305 | 3714 | 1857.0 | 128.25 | 64.1 | PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data. | Daniel R Roe, Thomas E Cheatham | J Chem Theory Comput | 2013 | 26583988 | Yes |
1306 | 1856 | 1856.0 | 48.5 | 48.5 | Hepatitis B virus infection. | W M Lee | N Engl J Med | 1997 | 9392700 | No |
1307 | 1854 | 1854.0 | 37.67 | 37.7 | The lasso method for variable selection in the Cox model. | R Tibshirani | Stat Med | 1997 | 9044528 | Yes |
1308 | 1854 | 1854.0 | 37.27 | 37.3 | Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. | R J Kaufman | Genes Dev | 1999 | 10346810 | No |
1309 | 1854 | 1854.0 | 43.01 | 43.0 | The retinal pigment epithelium in visual function. | Olaf Strauss | Physiol Rev | 2005 | 15987797 | No |
1310 | 5560 | 1853.3 | 138.81 | 46.3 | Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. | Z N Oltvai, C L Milliman, S J Korsmeyer | Cell | 1993 | 8358790 | Yes |
1311 | 3706 | 1853.0 | 109.83 | 54.9 | Photoperoxidation in isolated chloroplasts. I. Kinetics and stoichiometry of fatty acid peroxidation. | R L Heath, L Packer | Arch Biochem Biophys | 1968 | 5655425 | Yes |
1312 | 3704 | 1852.0 | 76.56 | 38.3 | Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. | C D Nobes, A Hall | Cell | 1995 | 7536630 | Yes |
1313 | 1851 | 1851.0 | 49.41 | 49.4 | Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic. | Robert E Marx | J Oral Maxillofac Surg | 2003 | 12966493 | Yes |
1314 | 3702 | 1851.0 | 112.89 | 56.4 | Threshold-free cluster enhancement: addressing problems of smoothing, threshold dependence and localisation in cluster inference. | Stephen M Smith, Thomas E Nichols | Neuroimage | 2009 | 18501637 | Yes |
1315 | 1849 | 1849.0 | 96.24 | 96.2 | Subjective well-being. | E Diener | Psychol Bull | 1984 | 6399758 | No |
1316 | 1848 | 1848.0 | 41.71 | 41.7 | Global cancer statistics in the year 2000. | D M Parkin | Lancet Oncol | 2001 | 11905707 | No |
1317 | 3695 | 1847.5 | 37.8 | 18.9 | Immunoassay of insulin with insulin-antibody precipitate. | C N Hales, P J Randle | Biochem J | 1963 | 13952078 | Yes |
1318 | 1847 | 1847.0 | 45.69 | 45.7 | Protein denaturation. | C Tanford | Adv Protein Chem | 1968 | 4882248 | No |
1319 | 3694 | 1847.0 | 78.07 | 39.0 | Monocyte and macrophage heterogeneity. | Siamon Gordon, Philip R Taylor | Nat Rev Immunol | 2005 | 16322748 | No |
1320 | 1846 | 1846.0 | 41.74 | 41.7 | Integrating cell-signalling pathways with NF-kappaB and IKK function. | Neil D Perkins | Nat Rev Mol Cell Biol | 2007 | 17183360 | No |
1321 | 14767 | 1845.9 | 415.47 | 51.9 | Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. | R K Saiki, D H Gelfand, S Stoffel, S J Scharf, R Higuchi, G T Horn, K B Mullis, H A Erlich | Science | 1988 | 2448875 | Yes |
1322 | 1845 | 1845.0 | 44.91 | 44.9 | Evolutionary relationship of DNA sequences in finite populations. | F Tajima | Genetics | 1983 | 6628982 | Yes |
1323 | 1844 | 1844.0 | 43.71 | 43.7 | The mitochondrial permeability transition pore and its role in cell death. | M Crompton | Biochem J | 1999 | 10393078 | No |
1324 | 5530 | 1843.3 | 251.14 | 83.7 | Fast and sensitive protein alignment using DIAMOND. | Benjamin Buchfink, Chao Xie, Daniel H Huson | Nat Methods | 2015 | 25402007 | Yes |
1325 | 3684 | 1842.0 | 110.43 | 55.2 | Development of a new resilience scale: the Connor-Davidson Resilience Scale (CD-RISC). | Kathryn M Connor, Jonathan R T Davidson | Depress Anxiety | 2003 | 12964174 | Yes |
1326 | 1841 | 1841.0 | 57.94 | 57.9 | The Gingival Index, the Plaque Index and the Retention Index Systems. | H Löe | J Periodontol | 1967 | 5237684 | Yes |
1327 | 7363 | 1840.8 | 177.99 | 44.5 | Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. | A Shevchenko, M Wilm, O Vorm, M Mann | Anal Chem | 1996 | 8779443 | Yes |
1328 | 5520 | 1840.0 | 121.42 | 40.5 | A rapid method for the isolation of functional thymus-derived murine lymphocytes. | M H Julius, E Simpson, L A Herzenberg | Eur J Immunol | 1973 | 4587740 | Yes |
1329 | 1840 | 1840.0 | 68.26 | 68.3 | Physiological aspects of primary hypertension. | B Folkow | Physiol Rev | 1982 | 6461865 | No |
1330 | 1840 | 1840.0 | 77.09 | 77.1 | The drug abuse screening test. | H A Skinner | Addict Behav | 1982 | 7183189 | Yes |
1331 | 1840 | 1840.0 | 41.62 | 41.6 | DNA topoisomerases. | J C Wang | Annu Rev Biochem | 1996 | 8811192 | No |
1332 | 1840 | 1840.0 | 119.0 | 119.0 | Toward understanding the origin and evolution of cellular organisms. | Minoru Kanehisa | Protein Sci | 2019 | 31441146 | No |
1333 | 3677 | 1838.5 | 309.84 | 154.9 | The biology, function, and biomedical applications of exosomes. | Raghu Kalluri, Valerie S LeBleu | Science | 2020 | 32029601 | No |
1334 | 7353 | 1838.2 | 336.57 | 84.1 | Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. | D J Sahn, A DeMaria, J Kisslo, A Weyman | Circulation | 1978 | 709763 | Yes |
1335 | 3676 | 1838.0 | 76.2 | 38.1 | Identification of common molecular subsequences. | T F Smith, M S Waterman | J Mol Biol | 1981 | 7265238 | Yes |
1336 | 1837 | 1837.0 | 66.12 | 66.1 | Why patients use alternative medicine: results of a national study. | J A Astin | JAMA | 1998 | 9605899 | Yes |
1337 | 1837 | 1837.0 | 48.38 | 48.4 | The comet assay for DNA damage and repair: principles, applications, and limitations. | Andrew R Collins | Mol Biotechnol | 2004 | 15004294 | No |
1338 | 9183 | 1836.6 | 219.37 | 43.9 | Mapping and quantifying mammalian transcriptomes by RNA-Seq. | Ali Mortazavi, Brian A Williams, Kenneth McCue, Lorian Schaeffer, Barbara Wold | Nat Methods | 2008 | 18516045 | Yes |
1339 | 3669 | 1834.5 | 120.39 | 60.2 | Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. | R A DeFronzo, E Ferrannini | Diabetes Care | 1991 | 2044434 | No |
1340 | 1834 | 1834.0 | 55.7 | 55.7 | The atom economy--a search for synthetic efficiency. | B M Trost | Science | 1991 | 1962206 | Yes |
1341 | 1834 | 1834.0 | 45.13 | 45.1 | Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials. | Fiona Turnbull | Lancet | 2003 | 14615107 | Yes |
1342 | 5500 | 1833.3 | 121.7 | 40.6 | Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. | Michael W Pfaffl, Graham W Horgan, Leo Dempfle | Nucleic Acids Res | 2002 | 11972351 | Yes |
1343 | 1830 | 1830.0 | 54.23 | 54.2 | An overview of brominated flame retardants in the environment. | Cynthia A de Wit | Chemosphere | 2002 | 11999784 | No |
1344 | 1829 | 1829.0 | 36.47 | 36.5 | MicroRNA biogenesis: coordinated cropping and dicing. | V Narry Kim | Nat Rev Mol Cell Biol | 2005 | 15852042 | No |
1345 | 1827 | 1827.0 | 49.33 | 49.3 | A classification of hand preference by association analysis. | M Annett | Br J Psychol | 1970 | 5457503 | Yes |
1346 | 3653 | 1826.5 | 76.2 | 38.1 | Cell death: critical control points. | Nika N Danial, Stanley J Korsmeyer | Cell | 2004 | 14744432 | No |
1347 | 1826 | 1826.0 | 12.81 | 12.8 | A Method Of Measuring Eye Movement Using A Scleral Search Coil In A Magnetic Field. | D A Robinson | IEEE Trans Biomed Eng | 1963 | 14121113 | Yes |
1348 | 1826 | 1826.0 | 50.18 | 50.2 | Systemic lupus erythematosus. | George C Tsokos | N Engl J Med | 2011 | 22129255 | No |
1349 | 1825 | 1825.0 | 84.05 | 84.0 | Determinants of low birth weight: methodological assessment and meta-analysis. | M S Kramer | Bull World Health Organ | 1987 | 3322602 | No |
1350 | 1825 | 1825.0 | 57.24 | 57.2 | Matching methods for causal inference: A review and a look forward. | Elizabeth A Stuart | Stat Sci | 2010 | 20871802 | Yes |
1351 | 3647 | 1823.5 | 81.4 | 40.7 | Amino acid substitution matrices from protein blocks. | S Henikoff, J G Henikoff | Proc Natl Acad Sci U S A | 1992 | 1438297 | Yes |
1352 | 3647 | 1823.5 | 110.61 | 55.3 | New method for quantitative determination of uronic acids. | N Blumenkrantz, G Asboe-Hansen | Anal Biochem | 1973 | 4269305 | Yes |
1353 | 1823 | 1823.0 | 46.77 | 46.8 | From sensation to cognition. | M M Mesulam | Brain | 1998 | 9648540 | No |
1354 | 1823 | 1823.0 | 48.18 | 48.2 | Molecular dissection of reactive astrogliosis and glial scar formation. | Michael V Sofroniew | Trends Neurosci | 2009 | 19782411 | No |
1355 | 5467 | 1822.3 | 162.57 | 54.2 | Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration. | Helga Thorvaldsdóttir, James T Robinson, Jill P Mesirov | Brief Bioinform | 2013 | 22517427 | Yes |
1356 | 1822 | 1822.0 | 35.43 | 35.4 | Cancer and the chemokine network. | Fran Balkwill | Nat Rev Cancer | 2004 | 15229479 | No |
1357 | 3642 | 1821.0 | 127.47 | 63.7 | Regulation of microRNA biogenesis. | Minju Ha, V Narry Kim | Nat Rev Mol Cell Biol | 2014 | 25027649 | No |
1358 | 3639 | 1819.5 | 131.29 | 65.6 | miRBase: annotating high confidence microRNAs using deep sequencing data. | Ana Kozomara, Sam Griffiths-Jones | Nucleic Acids Res | 2014 | 24275495 | Yes |
1359 | 5455 | 1818.3 | 194.96 | 65.0 | Molecular mechanisms of epithelial-mesenchymal transition. | Samy Lamouille, Jian Xu, Rik Derynck | Nat Rev Mol Cell Biol | 2014 | 24556840 | No |
1360 | 3636 | 1818.0 | 98.94 | 49.5 | Biofilms: survival mechanisms of clinically relevant microorganisms. | Rodney M Donlan, J William Costerton | Clin Microbiol Rev | 2002 | 11932229 | No |
1361 | 1818 | 1818.0 | 0.0 | 0.0 | The influence of some cations on an adenosine triphosphatase from peripheral nerves. | J C Skou | Biochim Biophys Acta | 1957 | 13412736 | Yes |
1362 | 5453 | 1817.7 | 480.76 | 160.3 | An interactive web-based dashboard to track COVID-19 in real time. | Ensheng Dong, Hongru Du, Lauren Gardner | Lancet Infect Dis | 2020 | 32087114 | Yes |
1363 | 1817 | 1817.0 | 39.81 | 39.8 | Gene finding in novel genomes. | Ian Korf | BMC Bioinformatics | 2004 | 15144565 | Yes |
1364 | 1817 | 1817.0 | 59.24 | 59.2 | Cognitive reserve. | Yaakov Stern | Neuropsychologia | 2009 | 19467352 | No |
1365 | 1816 | 1816.0 | 35.67 | 35.7 | Evolutionary rate at the molecular level. | M Kimura | Nature | 1968 | 5637732 | Yes |
1366 | 1815 | 1815.0 | 70.88 | 70.9 | Predicting basal metabolic rate, new standards and review of previous work. | W N Schofield | Hum Nutr Clin Nutr | 1985 | 4044297 | Yes |
1367 | 1815 | 1815.0 | 69.83 | 69.8 | Reliability and validity studies of the WHO--Composite International Diagnostic Interview (CIDI): a critical review. | H U Wittchen | J Psychiatr Res | 1994 | 8064641 | No |
1368 | 1811 | 1811.0 | 36.63 | 36.6 | Molecular regulation of vessel maturation. | Rakesh K Jain | Nat Med | 2003 | 12778167 | No |
1369 | 1810 | 1810.0 | 58.99 | 59.0 | Heavy metal intensification of DAB-based HRP reaction product. | J C Adams | J Histochem Cytochem | 1981 | 7252134 | Yes |
1370 | 3614 | 1807.0 | 96.45 | 48.2 | Variations in the pattern of pubertal changes in boys. | W A Marshall, J M Tanner | Arch Dis Child | 1970 | 5440182 | Yes |
1371 | 5418 | 1806.0 | 102.81 | 34.3 | Surfing the p53 network. | B Vogelstein, D Lane, A J Levine | Nature | 2000 | 11099028 | No |
1372 | 1805 | 1805.0 | 57.31 | 57.3 | Postsynaptic supersensitivity after 6-hydroxy-dopamine induced degeneration of the nigro-striatal dopamine system. | U Ungerstedt | Acta Physiol Scand Suppl | 1971 | 4332693 | Yes |
1373 | 1805 | 1805.0 | 18.66 | 18.7 | Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal. | S Cohen | J Biol Chem | 1962 | 13880319 | Yes |
1374 | 3609 | 1804.5 | 92.14 | 46.1 | Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. | K D McCarthy, J de Vellis | J Cell Biol | 1980 | 6248568 | Yes |
1375 | 7217 | 1804.2 | 175.25 | 43.8 | Improved optimization for the robust and accurate linear registration and motion correction of brain images. | Mark Jenkinson, Peter Bannister, Michael Brady, Stephen Smith | Neuroimage | 2002 | 12377157 | Yes |
1376 | 1804 | 1804.0 | 48.53 | 48.5 | New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. | R Y Tsien | Biochemistry | 1980 | 6770893 | Yes |
1377 | 1804 | 1804.0 | 49.13 | 49.1 | Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution. | H LeVine | Protein Sci | 1993 | 8453378 | Yes |
1378 | 3608 | 1804.0 | 104.75 | 52.4 | Molecular mechanisms and clinical applications of angiogenesis. | Peter Carmeliet, Rakesh K Jain | Nature | 2011 | 21593862 | No |
1379 | 1802 | 1802.0 | 66.23 | 66.2 | The Resonating Valence Bond State in La2CuO4 and Superconductivity. | P W Anderson | Science | 1987 | 17818979 | Yes |
1380 | 3594 | 1797.0 | 86.29 | 43.1 | Protein folding in the cell. | M J Gething, J Sambrook | Nature | 1992 | 1731198 | No |
1381 | 1797 | 1797.0 | 0.0 | 0.0 | Cognitive maps in rats and men. | E C Tolman | Psychol Rev | 1948 | 18870876 | Yes |
1382 | 1794 | 1794.0 | 42.37 | 42.4 | Type III protein secretion systems in bacterial pathogens of animals and plants. | C J Hueck | Microbiol Mol Biol Rev | 1998 | 9618447 | No |
1383 | 3588 | 1794.0 | 87.04 | 43.5 | Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. | Christian Haass, Dennis J Selkoe | Nat Rev Mol Cell Biol | 2007 | 17245412 | No |
1384 | 3587 | 1793.5 | 159.96 | 80.0 | Multiple receptors for dopamine. | J W Kebabian, D B Calne | Nature | 1979 | 215920 | No |
1385 | 1793 | 1793.0 | 98.27 | 98.3 | Estimability and estimation in case-referent studies. | O Miettinen | Am J Epidemiol | 1976 | 1251836 | Yes |
1386 | 1793 | 1793.0 | 56.41 | 56.4 | Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. | M Zasloff | Proc Natl Acad Sci U S A | 1987 | 3299384 | Yes |
1387 | 1793 | 1793.0 | 62.53 | 62.5 | A cortical network for directed attention and unilateral neglect. | M M Mesulam | Ann Neurol | 1981 | 7032417 | No |
1388 | 3586 | 1793.0 | 100.03 | 50.0 | EQ-5D: a measure of health status from the EuroQol Group. | R Rabin, F de Charro | Ann Med | 2001 | 11491192 | No |
1389 | 1793 | 1793.0 | 42.45 | 42.5 | Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. | D Lavanchy | J Viral Hepat | 2004 | 14996343 | No |
1390 | 1793 | 1793.0 | 39.62 | 39.6 | Recognition of microorganisms and activation of the immune response. | Ruslan Medzhitov | Nature | 2007 | 17943118 | No |
1391 | 1792 | 1792.0 | 49.2 | 49.2 | Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus. | Ralph A Defronzo | Diabetes | 2009 | 19336687 | No |
1392 | 1792 | 1792.0 | 43.29 | 43.3 | Integration, scaling, space-group assignment and post-refinement. | Wolfgang Kabsch | Acta Crystallogr D Biol Crystallogr | 2010 | 20124693 | Yes |
1393 | 1791 | 1791.0 | 35.85 | 35.9 | The effect of infections on susceptibility to autoimmune and allergic diseases. | Jean-Francois Bach | N Engl J Med | 2002 | 12239261 | No |
1394 | 1791 | 1791.0 | 0.0 | 0.0 | The measurement of volume changes in human limbs. | R J Whitney | J Physiol | 1953 | 13085295 | Yes |
1395 | 1790 | 1790.0 | 51.37 | 51.4 | Perceptual symbol systems. | L W Barsalou | Behav Brain Sci | 1999 | 11301525 | No |
1396 | 8947 | 1789.4 | 234.3 | 46.9 | Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. | Sarah Wild, Gojka Roglic, Anders Green, Richard Sicree, Hilary King | Diabetes Care | 2004 | 15111519 | Yes |
1397 | 3573 | 1786.5 | 92.21 | 46.1 | Receptive fields and functional architecture of monkey striate cortex. | D H Hubel, T N Wiesel | J Physiol | 1968 | 4966457 | Yes |
1398 | 10718 | 1786.3 | 313.14 | 52.2 | Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. | Ronald C Kessler, Patricia Berglund, Olga Demler, Robert Jin, Kathleen R Merikangas, Ellen E Walters | Arch Gen Psychiatry | 2005 | 15939837 | Yes |
1399 | 1785 | 1785.0 | 36.61 | 36.6 | Structure and regulation of voltage-gated Ca2+ channels. | W A Catterall | Annu Rev Cell Dev Biol | 2000 | 11031246 | No |
1400 | 7139 | 1784.8 | 198.6 | 49.6 | Comorbidity measures for use with administrative data. | A Elixhauser, C Steiner, D R Harris, R M Coffey | Med Care | 1998 | 9431328 | Yes |
1401 | 1784 | 1784.0 | 58.59 | 58.6 | The crisis in antibiotic resistance. | H C Neu | Science | 1992 | 1509257 | No |
1402 | 5352 | 1784.0 | 161.55 | 53.9 | Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. | P A Wolf, R D Abbott, W B Kannel | Stroke | 1991 | 1866765 | Yes |
1403 | 3563 | 1781.5 | 178.03 | 89.0 | Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. | M Mihara, M Uchiyama | Anal Biochem | 1978 | 655387 | Yes |
1404 | 3563 | 1781.5 | 88.54 | 44.3 | Maturation of the head of bacteriophage T4. I. DNA packaging events. | U K Laemmli, M Favre | J Mol Biol | 1973 | 4204102 | Yes |
1405 | 1781 | 1781.0 | 58.82 | 58.8 | Large-scale neurocognitive networks and distributed processing for attention, language, and memory. | M M Mesulam | Ann Neurol | 1990 | 2260847 | No |
1406 | 1780 | 1780.0 | 47.09 | 47.1 | Interleukin-6: an overview. | J Van Snick | Annu Rev Immunol | 1990 | 2188664 | No |
1407 | 1780 | 1780.0 | 66.85 | 66.8 | Cognitive reserve in ageing and Alzheimer's disease. | Yaakov Stern | Lancet Neurol | 2012 | 23079557 | No |
1408 | 5339 | 1779.7 | 111.48 | 37.2 | A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays. | J H Zhang, T D Chung, K R Oldenburg | J Biomol Screen | 1999 | 10838414 | Yes |
1409 | 1777 | 1777.0 | 48.72 | 48.7 | Leptospirosis. | P N Levett | Clin Microbiol Rev | 2001 | 11292640 | No |
1410 | 1777 | 1777.0 | 49.35 | 49.4 | Porous scaffold design for tissue engineering. | Scott J Hollister | Nat Mater | 2005 | 16003400 | No |
1411 | 1776 | 1776.0 | 35.95 | 36.0 | Points of control in inflammation. | Carl Nathan | Nature | 2002 | 12490957 | No |
1412 | 1775 | 1775.0 | 57.91 | 57.9 | Pineal melatonin: cell biology of its synthesis and of its physiological interactions. | R J Reiter | Endocr Rev | 1991 | 1649044 | No |
1413 | 1774 | 1774.0 | 57.4 | 57.4 | The inverse care law. | J T Hart | Lancet | 1971 | 4100731 | Yes |
1414 | 1773 | 1773.0 | 58.86 | 58.9 | Drugs of abuse: anatomy, pharmacology and function of reward pathways. | G F Koob | Trends Pharmacol Sci | 1992 | 1604710 | No |
1415 | 3546 | 1773.0 | 128.83 | 64.4 | The need to belong: desire for interpersonal attachments as a fundamental human motivation. | R F Baumeister, M R Leary | Psychol Bull | 1995 | 7777651 | No |
1416 | 1772 | 1772.0 | 32.76 | 32.8 | Cellular roles of DNA topoisomerases: a molecular perspective. | James C Wang | Nat Rev Mol Cell Biol | 2002 | 12042765 | No |
1417 | 1770 | 1770.0 | 53.9 | 53.9 | Social relationships and health. | Sheldon Cohen | Am Psychol | 2004 | 15554821 | No |
1418 | 1770 | 1770.0 | 43.53 | 43.5 | Adipose tissue, adipokines, and inflammation. | Giamila Fantuzzi | J Allergy Clin Immunol | 2005 | 15867843 | No |
1419 | 3535 | 1767.5 | 88.53 | 44.3 | The biology of vascular endothelial growth factor. | N Ferrara, T Davis-Smyth | Endocr Rev | 1997 | 9034784 | No |
1420 | 1767 | 1767.0 | 108.65 | 108.7 | Making sense of implementation theories, models and frameworks. | Per Nilsen | Implement Sci | 2015 | 25895742 | Yes |
1421 | 1765 | 1765.0 | 47.85 | 47.9 | G proteins and dual control of adenylate cyclase. | A G Gilman | Cell | 1984 | 6321035 | Yes |
1422 | 5292 | 1764.0 | 139.52 | 46.5 | Median-joining networks for inferring intraspecific phylogenies. | H J Bandelt, P Forster, A Röhl | Mol Biol Evol | 1999 | 10331250 | Yes |
1423 | 1764 | 1764.0 | 47.35 | 47.4 | What we can do and what we cannot do with fMRI. | Nikos K Logothetis | Nature | 2008 | 18548064 | No |
1424 | 7055 | 1763.8 | 138.32 | 34.6 | Stem cells, cancer, and cancer stem cells. | T Reya, S J Morrison, M F Clarke, I L Weissman | Nature | 2001 | 11689955 | No |
1425 | 1763 | 1763.0 | 37.73 | 37.7 | Oogenesis in Xenopus laevis (Daudin). I. Stages of oocyte development in laboratory maintained animals. | J N Dumont | J Morphol | 1972 | 4109871 | Yes |
1426 | 3526 | 1763.0 | 126.46 | 63.2 | Pain assessment: global use of the Brief Pain Inventory. | C S Cleeland, K M Ryan | Ann Acad Med Singap | 1994 | 8080219 | No |
1427 | 1763 | 1763.0 | 36.05 | 36.0 | An extensively modified version of MolScript that includes greatly enhanced coloring capabilities. | R M Esnouf | J Mol Graph Model | 1997 | 9385560 | Yes |
1428 | 1763 | 1763.0 | 0.0 | 0.0 | The reaction of acetylcholine and other carboxylic acid derivatives with hydroxylamine, and its analytical application. | S Hestrin | J Biol Chem | 1949 | 18133390 | Yes |
1429 | 1760 | 1760.0 | 40.11 | 40.1 | Steroid receptor regulated transcription of specific genes and gene networks. | K R Yamamoto | Annu Rev Genet | 1985 | 3909942 | No |
1430 | 1760 | 1760.0 | 35.99 | 36.0 | Protein homology detection by HMM-HMM comparison. | Johannes Söding | Bioinformatics | 2005 | 15531603 | Yes |
1431 | 1759 | 1759.0 | 44.79 | 44.8 | The pathophysiology of tumor necrosis factors. | P Vassalli | Annu Rev Immunol | 1992 | 1590993 | No |
1432 | 3517 | 1758.5 | 90.6 | 45.3 | Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation. | M A Nitsche, W Paulus | J Physiol | 2000 | 10990547 | Yes |
1433 | 1758 | 1758.0 | 61.08 | 61.1 | The role of hormone receptors and GTP-regulatory proteins in membrane transduction. | M Rodbell | Nature | 1980 | 6101906 | Yes |
1434 | 1758 | 1758.0 | 42.36 | 42.4 | Growth of the plant cell wall. | Daniel J Cosgrove | Nat Rev Mol Cell Biol | 2005 | 16261190 | No |
1435 | 17579 | 1757.9 | 550.04 | 55.0 | Measurement of protein using bicinchoninic acid. | P K Smith, R I Krohn, G T Hermanson, A K Mallia, F H Gartner, M D Provenzano, E K Fujimoto, N M Goeke, B J Olson, D C Klenk | Anal Biochem | 1985 | 3843705 | Yes |
1436 | 1757 | 1757.0 | 48.81 | 48.8 | Transposition and fusion of the lac genes to selected promoters in Escherichia coli using bacteriophage lambda and Mu. | M J Casadaban | J Mol Biol | 1976 | 781293 | Yes |
1437 | 1757 | 1757.0 | 18.6 | 18.6 | Chromatin structure: a repeating unit of histones and DNA. | R D Kornberg | Science | 1974 | 4825889 | Yes |
1438 | 1757 | 1757.0 | 49.23 | 49.2 | Oxidative stress: oxidants and antioxidants. | H Sies | Exp Physiol | 1997 | 9129943 | No |
1439 | 1757 | 1757.0 | 0.0 | 0.0 | A personality scale of manifest anxiety. | J A Taylor | J Abnorm Psychol | 1953 | 13052352 | Yes |
1440 | 1756 | 1756.0 | 46.33 | 46.3 | Oxidative stress and neurodegeneration: where are we now? | Barry Halliwell | J Neurochem | 2006 | 16805774 | No |
1441 | 3511 | 1755.5 | 86.52 | 43.3 | Matrix metalloproteinases. | H Nagase, J F Woessner | J Biol Chem | 1999 | 10419448 | No |
1442 | 3510 | 1755.0 | 108.61 | 54.3 | Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. | F Denizot, R Lang | J Immunol Methods | 1986 | 3486233 | Yes |
1443 | 3509 | 1754.5 | 49.07 | 24.5 | A complementation analysis of the restriction and modification of DNA in Escherichia coli. | H W Boyer, D Roulland-Dussoix | J Mol Biol | 1969 | 4896022 | Yes |
1444 | 3508 | 1754.0 | 136.51 | 68.3 | Assays of glutathione peroxidase. | L Flohé, W A Günzler | Methods Enzymol | 1984 | 6727659 | Yes |
1445 | 1754 | 1754.0 | 38.83 | 38.8 | The synaptic vesicle cycle: a cascade of protein-protein interactions. | T C Südhof | Nature | 1995 | 7791897 | No |
1446 | 1754 | 1754.0 | 43.98 | 44.0 | Flavonoid biosynthesis. A colorful model for genetics, biochemistry, cell biology, and biotechnology. | B Winkel-Shirley | Plant Physiol | 2001 | 11402179 | No |
1447 | 5261 | 1753.7 | 139.11 | 46.4 | The metabolic syndrome--a new worldwide definition. | K George M M Alberti, Paul Zimmet, Jonathan Shaw | Lancet | 2005 | 16182882 | Yes |
1448 | 7009 | 1752.2 | 270.38 | 67.6 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | Int J Surg | 2010 | 20171303 | No |
1449 | 1752 | 1752.0 | 40.64 | 40.6 | Areas, volumes, packing and protein structure. | F M Richards | Annu Rev Biophys Bioeng | 1977 | 326146 | No |
1450 | 3504 | 1752.0 | 138.49 | 69.2 | ROS function in redox signaling and oxidative stress. | Michael Schieber, Navdeep S Chandel | Curr Biol | 2014 | 24845678 | No |
1451 | 12262 | 1751.7 | 296.82 | 42.4 | Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. | William C Knowler, Elizabeth Barrett-Connor, Sarah E Fowler, Richard F Hamman, John M Lachin, Elizabeth A Walker, David M Nathan | N Engl J Med | 2002 | 11832527 | Yes |
1452 | 1751 | 1751.0 | 55.07 | 55.1 | The stress response in fish. | S E Wendelaar Bonga | Physiol Rev | 1997 | 9234959 | No |
1453 | 1750 | 1750.0 | 46.02 | 46.0 | Chlorpromazine equivalent doses for the newer atypical antipsychotics. | Scott W Woods | J Clin Psychiatry | 2003 | 12823080 | No |
1454 | 1749 | 1749.0 | 36.42 | 36.4 | Excitatory actions of gaba during development: the nature of the nurture. | Yehezkel Ben-Ari | Nat Rev Neurosci | 2002 | 12209121 | No |
1455 | 3496 | 1748.0 | 92.65 | 46.3 | Prediction of protein antigenic determinants from amino acid sequences. | T P Hopp, K R Woods | Proc Natl Acad Sci U S A | 1981 | 6167991 | Yes |
1456 | 3494 | 1747.0 | 73.09 | 36.5 | Why do cancers have high aerobic glycolysis? | Robert A Gatenby, Robert J Gillies | Nat Rev Cancer | 2004 | 15516961 | No |
1457 | 3494 | 1747.0 | 85.43 | 42.7 | Macrophage diversity enhances tumor progression and metastasis. | Bin-Zhi Qian, Jeffrey W Pollard | Cell | 2010 | 20371344 | No |
1458 | 1747 | 1747.0 | 38.51 | 38.5 | The hippo signaling pathway in development and cancer. | Duojia Pan | Dev Cell | 2010 | 20951342 | No |
1459 | 1746 | 1746.0 | 57.09 | 57.1 | Serum albumin. | T Peters | Adv Protein Chem | 1985 | 3904348 | No |
1460 | 1746 | 1746.0 | 44.0 | 44.0 | Hydrogels for biomedical applications. | Allan S Hoffman | Adv Drug Deliv Rev | 2002 | 11755703 | No |
1461 | 3491 | 1745.5 | 74.67 | 37.3 | Insulin signalling and the regulation of glucose and lipid metabolism. | A R Saltiel, C R Kahn | Nature | 2001 | 11742412 | Yes |
1462 | 1744 | 1744.0 | 37.75 | 37.8 | ATPase activity of myosin correlated with speed of muscle shortening. | M Bárány | J Gen Physiol | 1967 | 4227924 | Yes |
1463 | 1744 | 1744.0 | 33.36 | 33.4 | Transplacental carcinogenesis by stilbestrol. | J Folkman | N Engl J Med | 1971 | 5556579 | Yes |
1464 | 3488 | 1744.0 | 148.52 | 74.3 | mTOR Signaling in Growth, Metabolism, and Disease. | Robert A Saxton, David M Sabatini | Cell | 2017 | 28283069 | No |
1465 | 3487 | 1743.5 | 97.13 | 48.6 | The precuneus: a review of its functional anatomy and behavioural correlates. | Andrea E Cavanna, Michael R Trimble | Brain | 2006 | 16399806 | No |
1466 | 1743 | 1743.0 | 41.93 | 41.9 | Why genes in pieces? | W Gilbert | Nature | 1978 | 622185 | Yes |
1467 | 5228 | 1742.7 | 141.77 | 47.3 | trimAl: a tool for automated alignment trimming in large-scale phylogenetic analyses. | Salvador Capella-Gutiérrez, José M Silla-Martínez, Toni Gabaldón | Bioinformatics | 2009 | 19505945 | Yes |
1468 | 3484 | 1742.0 | 94.63 | 47.3 | Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. | K B Mullis, F A Faloona | Methods Enzymol | 1987 | 3431465 | Yes |
1469 | 1742 | 1742.0 | 46.95 | 47.0 | Oxidative stress hypothesis in Alzheimer's disease. | W R Markesbery | Free Radic Biol Med | 1997 | 9165306 | No |
1470 | 1742 | 1742.0 | 42.09 | 42.1 | Clinical application of C-reactive protein for cardiovascular disease detection and prevention. | Paul M Ridker | Circulation | 2003 | 12551853 | No |
1471 | 1742 | 1742.0 | 36.62 | 36.6 | Maintenance of C. elegans. | Theresa Stiernagle | WormBook | 2006 | 18050451 | No |
1472 | 1741 | 1741.0 | 71.54 | 71.5 | Dynamic properties of mammalian skeletal muscles. | R I Close | Physiol Rev | 1972 | 4256989 | No |
1473 | 1741 | 1741.0 | 54.42 | 54.4 | Glutamate: a neurotransmitter in mammalian brain. | F Fonnum | J Neurochem | 1984 | 6139418 | No |
1474 | 3480 | 1740.0 | 122.95 | 61.5 | The transtheoretical model of health behavior change. | J O Prochaska, W F Velicer | Am J Health Promot | 1997 | 10170434 | No |
1475 | 3479 | 1739.5 | 73.11 | 36.6 | Integrin signaling. | F G Giancotti, E Ruoslahti | Science | 1999 | 10446041 | No |
1476 | 3479 | 1739.5 | 119.58 | 59.8 | The Oswestry Disability Index. | J C Fairbank, P B Pynsent | Spine (Phila Pa 1976) | 2000 | 11074683 | No |
1477 | 3477 | 1738.5 | 113.94 | 57.0 | Saliency, switching, attention and control: a network model of insula function. | Vinod Menon, Lucina Q Uddin | Brain Struct Funct | 2010 | 20512370 | No |
1478 | 1738 | 1738.0 | 61.85 | 61.9 | Cyclosporine. | B D Kahan | N Engl J Med | 1989 | 2687689 | No |
1479 | 1737 | 1737.0 | 52.21 | 52.2 | Aging, cellular senescence, and cancer. | Judith Campisi | Annu Rev Physiol | 2013 | 23140366 | No |
1480 | 6941 | 1735.2 | 135.64 | 33.9 | Transformation of intact yeast cells treated with alkali cations. | H Ito, Y Fukuda, K Murata, A Kimura | J Bacteriol | 1983 | 6336730 | Yes |
1481 | 1735 | 1735.0 | 40.68 | 40.7 | Solvent-accessible surfaces of proteins and nucleic acids. | M L Connolly | Science | 1983 | 6879170 | Yes |
1482 | 3470 | 1735.0 | 80.46 | 40.2 | The incidence of congenital heart disease. | Julien I E Hoffman, Samuel Kaplan | J Am Coll Cardiol | 2002 | 12084585 | No |
1483 | 1735 | 1735.0 | 74.41 | 74.4 | Optical properties of biological tissues: a review. | Steven L Jacques | Phys Med Biol | 2013 | 23666068 | No |
1484 | 3468 | 1734.0 | 90.99 | 45.5 | Cloned glutamate receptors. | M Hollmann, S Heinemann | Annu Rev Neurosci | 1994 | 8210177 | No |
1485 | 1734 | 1734.0 | 35.46 | 35.5 | Oxidative stress shortens telomeres. | Thomas von Zglinicki | Trends Biochem Sci | 2002 | 12114022 | Yes |
1486 | 3468 | 1734.0 | 91.94 | 46.0 | The mirror-neuron system. | Giacomo Rizzolatti, Laila Craighero | Annu Rev Neurosci | 2004 | 15217330 | No |
1487 | 5200 | 1733.3 | 112.73 | 37.6 | Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. | A Nicholls, K A Sharp, B Honig | Proteins | 1991 | 1758883 | Yes |
1488 | 1733 | 1733.0 | 64.69 | 64.7 | Simple proton spectroscopic imaging. | W T Dixon | Radiology | 1984 | 6089263 | Yes |
1489 | 1733 | 1733.0 | 31.42 | 31.4 | CD4+ CD25+ suppressor T cells: more questions than answers. | Ethan M Shevach | Nat Rev Immunol | 2002 | 12093005 | No |
1490 | 1733 | 1733.0 | 58.56 | 58.6 | Functional and effective connectivity: a review. | Karl J Friston | Brain Connect | 2011 | 22432952 | No |
1491 | 1732 | 1732.0 | 40.87 | 40.9 | Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining. | A Krishan | J Cell Biol | 1975 | 49354 | Yes |
1492 | 1731 | 1731.0 | 59.85 | 59.9 | Falls in older people: epidemiology, risk factors and strategies for prevention. | Laurence Z Rubenstein | Age Ageing | 2006 | 16926202 | No |
1493 | 1730 | 1730.0 | 38.28 | 38.3 | Mode of cell migration to the superficial layers of fetal monkey neocortex. | P Rakic | J Comp Neurol | 1972 | 4624784 | Yes |
1494 | 1730 | 1730.0 | 59.43 | 59.4 | Free radicals, antioxidants, and human disease: curiosity, cause, or consequence? | B Halliwell | Lancet | 1994 | 7915779 | No |
1495 | 1730 | 1730.0 | 65.38 | 65.4 | Antibiotics in the aquatic environment--a review--part I. | Klaus Kümmerer | Chemosphere | 2009 | 19185900 | No |
1496 | 3459 | 1729.5 | 99.43 | 49.7 | Alzheimer's disease. | Henry W Querfurth, Frank M LaFerla | N Engl J Med | 2010 | 20107219 | No |
1497 | 1729 | 1729.0 | 0.0 | 0.0 | The recurrence of intracranial meningiomas after surgical treatment. | D Simpson | J Neurol Neurosurg Psychiatry | 1957 | 13406590 | Yes |
1498 | 1728 | 1728.0 | 37.53 | 37.5 | Determination of free amino groups in proteins by trinitrobenzenesulfonic acid. | A F Habeeb | Anal Biochem | 1966 | 4161471 | Yes |
1499 | 1727 | 1727.0 | 60.68 | 60.7 | Changes in the visual system of monocularly sutured or enucleated cats demonstrable with cytochrome oxidase histochemistry. | M Wong-Riley | Brain Res | 1979 | 223730 | Yes |
1500 | 1726 | 1726.0 | 42.88 | 42.9 | Cellular basis of working memory. | P S Goldman-Rakic | Neuron | 1995 | 7695894 | No |
1501 | 3452 | 1726.0 | 82.4 | 41.2 | Origins and Mechanisms of miRNAs and siRNAs. | Richard W Carthew, Erik J Sontheimer | Cell | 2009 | 19239886 | No |
1502 | 6901 | 1725.2 | 452.21 | 113.1 | Rayyan-a web and mobile app for systematic reviews. | Mourad Ouzzani, Hossam Hammady, Zbys Fedorowicz, Ahmed Elmagarmid | Syst Rev | 2016 | 27919275 | Yes |
1503 | 3450 | 1725.0 | 78.66 | 39.3 | Shared principles in NF-kappaB signaling. | Matthew S Hayden, Sankar Ghosh | Cell | 2008 | 18267068 | No |
1504 | 1724 | 1724.0 | 49.73 | 49.7 | Risk and safety of repetitive transcranial magnetic stimulation: report and suggested guidelines from the International Workshop on the Safety of Repetitive Transcranial Magnetic Stimulation, June 5-7, 1996. | E M Wassermann | Electroencephalogr Clin Neurophysiol | 1998 | 9474057 | No |
1505 | 1724 | 1724.0 | 0.0 | 0.0 | The general adaptation syndrome and the diseases of adaptation. | H Selye | J Clin Endocrinol Metab | 1946 | 21025115 | Yes |
1506 | 3447 | 1723.5 | 177.17 | 88.6 | Interrater reliability of a modified Ashworth scale of muscle spasticity. | R W Bohannon, M B Smith | Phys Ther | 1987 | 3809245 | Yes |
1507 | 3447 | 1723.5 | 108.97 | 54.5 | Genome editing. The new frontier of genome engineering with CRISPR-Cas9. | Jennifer A Doudna, Emmanuelle Charpentier | Science | 2014 | 25430774 | No |
1508 | 1722 | 1722.0 | 56.11 | 56.1 | Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli. | E M Witkin | Bacteriol Rev | 1976 | 795416 | No |
1509 | 1722 | 1722.0 | 52.19 | 52.2 | Genetic differentiation and estimation of gene flow from F-statistics under isolation by distance. | F Rousset | Genetics | 1997 | 9093870 | Yes |
1510 | 10332 | 1722.0 | 313.45 | 52.2 | New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. | Stéphane Guindon, Jean-François Dufayard, Vincent Lefort, Maria Anisimova, Wim Hordijk, Olivier Gascuel | Syst Biol | 2010 | 20525638 | Yes |
1511 | 5163 | 1721.0 | 116.86 | 39.0 | Inflammation and atherosclerosis. | Peter Libby, Paul M Ridker, Attilio Maseri | Circulation | 2002 | 11877368 | No |
1512 | 5161 | 1720.3 | 229.76 | 76.6 | Some statistical methods useful in circulation research. | S Wallenstein, C L Zucker, J L Fleiss | Circ Res | 1980 | 7379260 | Yes |
1513 | 1719 | 1719.0 | 64.64 | 64.6 | Modeling and variable selection in epidemiologic analysis. | S Greenland | Am J Public Health | 1989 | 2916724 | Yes |
1514 | 1719 | 1719.0 | 33.37 | 33.4 | Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. | Judith Campisi | Cell | 2005 | 15734683 | No |
1515 | 1718 | 1718.0 | 43.75 | 43.8 | The smooth muscle cell. II. Growth of smooth muscle in culture and formation of elastic fibers. | R Ross | J Cell Biol | 1971 | 4327464 | Yes |
1516 | 3436 | 1718.0 | 0.0 | 0.0 | Convergent and discriminant validation by the multitrait-multimethod matrix. | D T Campbell, D W Fiske | Psychol Bull | 1959 | 13634291 | Yes |
1517 | 3436 | 1718.0 | 124.67 | 62.3 | The integrative review: updated methodology. | Robin Whittemore, Kathleen Knafl | J Adv Nurs | 2005 | 16268861 | Yes |
1518 | 3436 | 1718.0 | 152.32 | 76.2 | Cancer immunotherapy using checkpoint blockade. | Antoni Ribas, Jedd D Wolchok | Science | 2018 | 29567705 | No |
1519 | 1715 | 1715.0 | 41.0 | 41.0 | Tricine-SDS-PAGE. | Hermann Schägger | Nat Protoc | 2006 | 17406207 | Yes |
1520 | 1714 | 1714.0 | 56.87 | 56.9 | Microalbuminuria predicts clinical proteinuria and early mortality in maturity-onset diabetes. | C E Mogensen | N Engl J Med | 1984 | 6690964 | Yes |
1521 | 3427 | 1713.5 | 86.96 | 43.5 | Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. | Steven E Nissen, Kathy Wolski | N Engl J Med | 2007 | 17517853 | Yes |
1522 | 1713 | 1713.0 | 40.41 | 40.4 | The relationship between the spleen colony-forming cell and the haemopoietic stem cell. | R Schofield | Blood Cells | 1978 | 747780 | Yes |
1523 | 1713 | 1713.0 | 44.56 | 44.6 | Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli. | G C Walker | Microbiol Rev | 1984 | 6371470 | No |
1524 | 1713 | 1713.0 | 32.41 | 32.4 | Network motifs: theory and experimental approaches. | Uri Alon | Nat Rev Genet | 2007 | 17510665 | No |
1525 | 3425 | 1712.5 | 83.12 | 41.6 | The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. | A E Bolton, W M Hunter | Biochem J | 1973 | 4733239 | Yes |
1526 | 3425 | 1712.5 | 147.1 | 73.5 | A standardized set of 260 pictures: norms for name agreement, image agreement, familiarity, and visual complexity. | J G Snodgrass, M Vanderwart | J Exp Psychol Hum Learn | 1980 | 7373248 | Yes |
1527 | 5136 | 1712.0 | 161.29 | 53.8 | Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. | H Esterbauer, R J Schaur, H Zollner | Free Radic Biol Med | 1991 | 1937131 | No |
1528 | 1712 | 1712.0 | 38.96 | 39.0 | Tumor angiogenesis. | Robert S Kerbel | N Engl J Med | 2008 | 18463380 | No |
1529 | 3423 | 1711.5 | 86.47 | 43.2 | Quantum dot bioconjugates for ultrasensitive nonisotopic detection. | W C Chan, S Nie | Science | 1998 | 9748158 | Yes |
1530 | 3420 | 1710.0 | 112.28 | 56.1 | A "Direct-Coloring" Thiocholine Method For Cholinesterases. | M J Karnovsky, L Roots | J Histochem Cytochem | 1964 | 14187330 | Yes |
1531 | 1710 | 1710.0 | 0.0 | 0.0 | Transformation Of Biochemically Deficient Strains Of Bacillus Subtilis By Deoxyribonucleate. | J Spizizen | Proc Natl Acad Sci U S A | 1958 | 16590310 | Yes |
1532 | 13679 | 1709.9 | 579.42 | 72.4 | The SILVA ribosomal RNA gene database project: improved data processing and web-based tools. | Christian Quast, Elmar Pruesse, Pelin Yilmaz, Jan Gerken, Timmy Schweer, Pablo Yarza, Jörg Peplies, Frank Oliver Glöckner | Nucleic Acids Res | 2013 | 23193283 | Yes |
1533 | 1709 | 1709.0 | 31.63 | 31.6 | How eukaryotic transcriptional activators work. | M Ptashne | Nature | 1988 | 3050531 | No |
1534 | 1709 | 1709.0 | 60.63 | 60.6 | Computerized transverse axial scanning (tomography). 1. Description of system. | G N Hounsfield | Br J Radiol | 1973 | 4757352 | Yes |
1535 | 1708 | 1708.0 | 38.48 | 38.5 | Effects of cytochalasin and phalloidin on actin. | J A Cooper | J Cell Biol | 1987 | 3312229 | No |
1536 | 1707 | 1707.0 | 52.22 | 52.2 | A measure of population subdivision based on microsatellite allele frequencies. | M Slatkin | Genetics | 1995 | 7705646 | Yes |
1537 | 1707 | 1707.0 | 41.58 | 41.6 | Maximum likelihood phylogenetic estimation from DNA sequences with variable rates over sites: approximate methods. | Z Yang | J Mol Evol | 1994 | 7932792 | Yes |
1538 | 3414 | 1707.0 | 73.71 | 36.9 | Fibroblasts in cancer. | Raghu Kalluri, Michael Zeisberg | Nat Rev Cancer | 2006 | 16572188 | No |
1539 | 3412 | 1706.0 | 129.74 | 64.9 | The three-factor eating questionnaire to measure dietary restraint, disinhibition and hunger. | A J Stunkard, S Messick | J Psychosom Res | 1985 | 3981480 | Yes |
1540 | 1704 | 1704.0 | 36.9 | 36.9 | Trastuzumab--mechanism of action and use in clinical practice. | Clifford A Hudis | N Engl J Med | 2007 | 17611206 | No |
1541 | 6814 | 1703.5 | 143.8 | 36.0 | Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. | E A Jaffe, R L Nachman, C G Becker, C R Minick | J Clin Invest | 1973 | 4355998 | Yes |
1542 | 1702 | 1702.0 | 45.12 | 45.1 | THE WATER-WATER CYCLE IN CHLOROPLASTS: Scavenging of Active Oxygens and Dissipation of Excess Photons. | Kozi Asada | Annu Rev Plant Physiol Plant Mol Biol | 1999 | 15012221 | Yes |
1543 | 1702 | 1702.0 | 69.36 | 69.4 | Whatever next? Predictive brains, situated agents, and the future of cognitive science. | Andy Clark | Behav Brain Sci | 2013 | 23663408 | No |
1544 | 17014 | 1701.4 | 539.76 | 54.0 | The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. | F C Arnett, S M Edworthy, D A Bloch, D J McShane, J F Fries, N S Cooper, L A Healey, S R Kaplan, M H Liang, H S Luthra | Arthritis Rheum | 1988 | 3358796 | Yes |
1545 | 3401 | 1700.5 | 145.09 | 72.5 | A fluorometric method for determination of oxidized and reduced glutathione in tissues. | P J Hissin, R Hilf | Anal Biochem | 1976 | 962076 | Yes |
1546 | 3399 | 1699.5 | 135.81 | 67.9 | Dermatology Life Quality Index (DLQI)--a simple practical measure for routine clinical use. | A Y Finlay, G K Khan | Clin Exp Dermatol | 1994 | 8033378 | Yes |
1547 | 1698 | 1698.0 | 45.44 | 45.4 | Integrins. | E Ruoslahti | J Clin Invest | 1991 | 1985087 | No |
1548 | 1698 | 1698.0 | 56.93 | 56.9 | Carboxylate-assisted transition-metal-catalyzed C-H bond functionalizations: mechanism and scope. | Lutz Ackermann | Chem Rev | 2011 | 21391562 | Yes |
1549 | 3395 | 1697.5 | 93.68 | 46.8 | Biochemistry of multidrug resistance mediated by the multidrug transporter. | M M Gottesman, I Pastan | Annu Rev Biochem | 1993 | 8102521 | No |
1550 | 3395 | 1697.5 | 343.78 | 171.9 | WHO Declares COVID-19 a Pandemic. | Domenico Cucinotta, Maurizio Vanelli | Acta Biomed | 2020 | 32191675 | Yes |
1551 | 8487 | 1697.4 | 210.26 | 42.1 | Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. | Alan S Go, Glenn M Chertow, Dongjie Fan, Charles E McCulloch, Chi-yuan Hsu | N Engl J Med | 2004 | 15385656 | Yes |
1552 | 1697 | 1697.0 | 75.87 | 75.9 | The micronucleus test. | W Schmid | Mutat Res | 1975 | 48190 | Yes |
1553 | 1697 | 1697.0 | 41.29 | 41.3 | The statistical analysis of enzyme kinetic data. | W W Cleland | Adv Enzymol Relat Areas Mol Biol | 1967 | 4881884 | No |
1554 | 1697 | 1697.0 | 55.06 | 55.1 | Validation of a decisional conflict scale. | A M O'Connor | Med Decis Making | 1995 | 7898294 | Yes |
1555 | 1697 | 1697.0 | 69.79 | 69.8 | Adverse health effects of high-effort/low-reward conditions. | J Siegrist | J Occup Health Psychol | 1996 | 9547031 | No |
1556 | 1697 | 1697.0 | 38.36 | 38.4 | Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): trends and problems. | S A Bustin | J Mol Endocrinol | 2002 | 12200227 | No |
1557 | 1697 | 1697.0 | 37.28 | 37.3 | AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. | D Grahame Hardie | Nat Rev Mol Cell Biol | 2007 | 17712357 | No |
1558 | 3394 | 1697.0 | 252.73 | 126.4 | Interactive Tree Of Life (iTOL) v4: recent updates and new developments. | Ivica Letunic, Peer Bork | Nucleic Acids Res | 2019 | 30931475 | Yes |
1559 | 1696 | 1696.0 | 38.89 | 38.9 | A graphic method for the determination and presentation of binding parameters in a complex system. | H E Rosenthal | Anal Biochem | 1967 | 6048188 | Yes |
1560 | 1696 | 1696.0 | 33.46 | 33.5 | The synaptic vesicle cycle. | Thomas C Sudhof | Annu Rev Neurosci | 2004 | 15217342 | No |
1561 | 1696 | 1696.0 | 53.95 | 54.0 | Receiver operating characteristic curve in diagnostic test assessment. | Jayawant N Mandrekar | J Thorac Oncol | 2010 | 20736804 | No |
1562 | 8478 | 1695.6 | 192.94 | 38.6 | Stages of embryonic development of the zebrafish. | C B Kimmel, W W Ballard, S R Kimmel, B Ullmann, T F Schilling | Dev Dyn | 1995 | 8589427 | Yes |
1563 | 3391 | 1695.5 | 109.22 | 54.6 | Separate visual pathways for perception and action. | M A Goodale, A D Milner | Trends Neurosci | 1992 | 1374953 | No |
1564 | 1695 | 1695.0 | 40.73 | 40.7 | The molecular genetics of cancer. | J M Bishop | Science | 1987 | 3541204 | No |
1565 | 3389 | 1694.5 | 110.65 | 55.3 | Role of free radicals and catalytic metal ions in human disease: an overview. | B Halliwell, J M Gutteridge | Methods Enzymol | 1990 | 2172697 | No |
1566 | 1694 | 1694.0 | 43.09 | 43.1 | Carbonic anhydrase: chemistry, physiology, and inhibition. | T H Maren | Physiol Rev | 1967 | 4964060 | No |
1567 | 6772 | 1693.0 | 286.09 | 71.5 | An inventory for measuring clinical anxiety: psychometric properties. | A T Beck, N Epstein, G Brown, R A Steer | J Consult Clin Psychol | 1988 | 3204199 | Yes |
1568 | 1693 | 1693.0 | 65.28 | 65.3 | Selenium and human health. | Margaret P Rayman | Lancet | 2012 | 22381456 | No |
1569 | 1692 | 1692.0 | 45.35 | 45.4 | The glomerular permeability determined by dextran clearance using Sephadex gel filtration. | C E Mogensen | Scand J Clin Lab Invest | 1968 | 5637478 | Yes |
1570 | 1692 | 1692.0 | 36.13 | 36.1 | Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. | S L Friedman | J Biol Chem | 2000 | 10644669 | No |
1571 | 10147 | 1691.2 | 284.2 | 47.4 | Positional cloning of the mouse obese gene and its human homologue. | Y Zhang, R Proenca, M Maffei, M Barone, L Leopold, J M Friedman | Nature | 1994 | 7984236 | Yes |
1572 | 1691 | 1691.0 | 68.15 | 68.2 | Negative symptoms in schizophrenia. Definition and reliability. | N C Andreasen | Arch Gen Psychiatry | 1982 | 7165477 | Yes |
1573 | 5072 | 1690.7 | 111.82 | 37.3 | An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. | J K Eng, A L McCormack, J R Yates | J Am Soc Mass Spectrom | 1994 | 24226387 | Yes |
1574 | 3380 | 1690.0 | 67.14 | 33.6 | An automated method for finding molecular complexes in large protein interaction networks. | Gary D Bader, Christopher W V Hogue | BMC Bioinformatics | 2003 | 12525261 | Yes |
1575 | 3378 | 1689.0 | 94.1 | 47.0 | Protective and pathogenic functions of macrophage subsets. | Peter J Murray, Thomas A Wynn | Nat Rev Immunol | 2011 | 21997792 | No |
1576 | 5061 | 1687.0 | 130.56 | 43.5 | The rapid generation of mutation data matrices from protein sequences. | D T Jones, W R Taylor, J M Thornton | Comput Appl Biosci | 1992 | 1633570 | Yes |
1577 | 3373 | 1686.5 | 67.66 | 33.8 | A guided tour into subcellular colocalization analysis in light microscopy. | S Bolte, F P Cordelières | J Microsc | 2006 | 17210054 | Yes |
1578 | 1686 | 1686.0 | 31.09 | 31.1 | Cyclin-dependent kinases: engines, clocks, and microprocessors. | D O Morgan | Annu Rev Cell Dev Biol | 1997 | 9442875 | No |
1579 | 1686 | 1686.0 | 32.43 | 32.4 | Generating samples under a Wright-Fisher neutral model of genetic variation. | Richard R Hudson | Bioinformatics | 2002 | 11847089 | Yes |
1580 | 3372 | 1686.0 | 78.34 | 39.2 | The BCL-2 protein family: opposing activities that mediate cell death. | Richard J Youle, Andreas Strasser | Nat Rev Mol Cell Biol | 2008 | 18097445 | No |
1581 | 1684 | 1684.0 | 55.3 | 55.3 | The polyvagal perspective. | Stephen W Porges | Biol Psychol | 2007 | 17049418 | No |
1582 | 1684 | 1684.0 | 39.65 | 39.6 | Angiogenesis: an organizing principle for drug discovery? | Judah Folkman | Nat Rev Drug Discov | 2007 | 17396134 | No |
1583 | 3368 | 1684.0 | 87.83 | 43.9 | Multiple sclerosis. | Alastair Compston, Alasdair Coles | Lancet | 2008 | 18970977 | Yes |
1584 | 8418 | 1683.6 | 285.36 | 57.1 | The hallmarks of aging. | Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer | Cell | 2013 | 23746838 | No |
1585 | 3367 | 1683.5 | 101.91 | 51.0 | The pathogenesis of rheumatoid arthritis. | Iain B McInnes, Georg Schett | N Engl J Med | 2011 | 22150039 | No |
1586 | 1683 | 1683.0 | 10.09 | 10.1 | Chromatographic Separation Of Human Brain Gangliosides. | L Svennerholm | J Neurochem | 1963 | 14066623 | Yes |
1587 | 8412 | 1682.4 | 321.22 | 64.2 | UCHIME improves sensitivity and speed of chimera detection. | Robert C Edgar, Brian J Haas, Jose C Clemente, Christopher Quince, Rob Knight | Bioinformatics | 2011 | 21700674 | Yes |
1588 | 1682 | 1682.0 | 59.89 | 59.9 | Amyloid deposits and amyloidosis. The beta-fibrilloses (first of two parts). | G G Glenner | N Engl J Med | 1980 | 6154243 | No |
1589 | 3364 | 1682.0 | 80.61 | 40.3 | CAP3: A DNA sequence assembly program. | X Huang, A Madan | Genome Res | 1999 | 10508846 | Yes |
1590 | 1682 | 1682.0 | 66.92 | 66.9 | Plastic Embedding Mixtures For Use In Electron Microscopy. | H H Mollenhauer | Stain Technol | 1964 | 14127791 | Yes |
1591 | 1681 | 1681.0 | 49.5 | 49.5 | Pedigrees of some mutant strains of Escherichia coli K-12. | B J Bachmann | Bacteriol Rev | 1972 | 4568763 | No |
1592 | 1681 | 1681.0 | 50.63 | 50.6 | Constructions of masculinity and their influence on men's well-being: a theory of gender and health. | W H Courtenay | Soc Sci Med | 2000 | 10741575 | No |
1593 | 1681 | 1681.0 | 0.0 | 0.0 | The theory and applications of the exchange of inert gas at the lungs and tissues. | S S Kety | Pharmacol Rev | 1951 | 14833874 | Yes |
1594 | 1680 | 1680.0 | 32.93 | 32.9 | Hox genes in vertebrate development. | R Krumlauf | Cell | 1994 | 7913880 | No |
1595 | 1679 | 1679.0 | 62.79 | 62.8 | Paced auditory serial-addition task: a measure of recovery from concussion. | D M Gronwall | Percept Mot Skills | 1977 | 866038 | Yes |
1596 | 5037 | 1679.0 | 109.08 | 36.4 | Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. | J E Darnell, I M Kerr, G R Stark | Science | 1994 | 8197455 | No |
1597 | 1679 | 1679.0 | 47.18 | 47.2 | The in vitro micronucleus technique. | M Fenech | Mutat Res | 2000 | 11113469 | No |
1598 | 3358 | 1679.0 | 83.75 | 41.9 | Protein structure prediction on the Web: a case study using the Phyre server. | Lawrence A Kelley, Michael J E Sternberg | Nat Protoc | 2009 | 19247286 | Yes |
1599 | 5035 | 1678.3 | 119.64 | 39.9 | Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. | Prateek Kumar, Steven Henikoff, Pauline C Ng | Nat Protoc | 2009 | 19561590 | Yes |
1600 | 1678 | 1678.0 | 38.66 | 38.7 | The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. | D M Kingsley | Genes Dev | 1994 | 8299934 | No |
1601 | 5034 | 1678.0 | 131.67 | 43.9 | A neural substrate of prediction and reward. | W Schultz, P Dayan, P R Montague | Science | 1997 | 9054347 | No |
1602 | 1676 | 1676.0 | 49.18 | 49.2 | Drugs which inhibit prostaglandin biosynthesis. | R J Flower | Pharmacol Rev | 1974 | 4208101 | Yes |
1603 | 1676 | 1676.0 | 34.16 | 34.2 | Neurotrophins and their receptors: a convergence point for many signalling pathways. | Moses V Chao | Nat Rev Neurosci | 2003 | 12671646 | No |
1604 | 1676 | 1676.0 | 18.41 | 18.4 | Impulses and Physiological States in Theoretical Models of Nerve Membrane. | R Fitzhugh | Biophys J | 1961 | 19431309 | Yes |
1605 | 3352 | 1676.0 | 155.18 | 77.6 | The amyloid hypothesis of Alzheimer's disease at 25 years. | Dennis J Selkoe, John Hardy | EMBO Mol Med | 2016 | 27025652 | No |
1606 | 1675 | 1675.0 | 49.74 | 49.7 | phangorn: phylogenetic analysis in R. | Klaus Peter Schliep | Bioinformatics | 2011 | 21169378 | Yes |
1607 | 3349 | 1674.5 | 71.52 | 35.8 | The epigenomics of cancer. | Peter A Jones, Stephen B Baylin | Cell | 2007 | 17320506 | No |
1608 | 3348 | 1674.0 | 69.58 | 34.8 | A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids. | D Wessel, U I Flügge | Anal Biochem | 1984 | 6731838 | Yes |
1609 | 3347 | 1673.5 | 84.2 | 42.1 | Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients. | S Schulman, C Kearon | J Thromb Haemost | 2005 | 15842354 | Yes |
1610 | 1673 | 1673.0 | 58.11 | 58.1 | Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture. | A H Conney | Cancer Res | 1982 | 6814745 | No |
1611 | 1672 | 1672.0 | 49.88 | 49.9 | Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture. | J A Miller | Cancer Res | 1970 | 4915745 | No |
1612 | 1672 | 1672.0 | 39.04 | 39.0 | A revolution in optical manipulation. | David G Grier | Nature | 2003 | 12917694 | No |
1613 | 3344 | 1672.0 | 50.65 | 25.3 | Determination of the base composition of deoxyribonucleic acid from its thermal denaturation temperature. | J Marmur, P Doty | J Mol Biol | 1962 | 14470099 | Yes |
1614 | 1672 | 1672.0 | 36.62 | 36.6 | Perceptions of epigenetics. | Adrian Bird | Nature | 2007 | 17522671 | Yes |
1615 | 1671 | 1671.0 | 53.88 | 53.9 | Synaptic density in human frontal cortex - developmental changes and effects of aging. | P R Huttenlocher | Brain Res | 1979 | 427544 | Yes |
1616 | 1671 | 1671.0 | 38.39 | 38.4 | NADPH oxidase: an update. | B M Babior | Blood | 1999 | 10029572 | No |
1617 | 6683 | 1670.8 | 192.31 | 48.1 | The validity of the Hospital Anxiety and Depression Scale. An updated literature review. | Ingvar Bjelland, Alv A Dahl, Tone Tangen Haug, Dag Neckelmann | J Psychosom Res | 2002 | 11832252 | No |
1618 | 6683 | 1670.8 | 224.39 | 56.1 | SignalP 4.0: discriminating signal peptides from transmembrane regions. | Thomas Nordahl Petersen, Søren Brunak, Gunnar von Heijne, Henrik Nielsen | Nat Methods | 2011 | 21959131 | Yes |
1619 | 3340 | 1670.0 | 79.06 | 39.5 | The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. | P Angel, M Karin | Biochim Biophys Acta | 1991 | 1751545 | No |
1620 | 1670 | 1670.0 | 39.84 | 39.8 | Inflammatory bowel disease: etiology and pathogenesis. | C Fiocchi | Gastroenterology | 1998 | 9649475 | No |
1621 | 1670 | 1670.0 | 38.52 | 38.5 | PLANT COLD ACCLIMATION: Freezing Tolerance Genes and Regulatory Mechanisms. | Michael F. Thomashow | Annu Rev Plant Physiol Plant Mol Biol | 1999 | 15012220 | Yes |
1622 | 3339 | 1669.5 | 82.92 | 41.5 | Receptors for purines and pyrimidines. | V Ralevic, G Burnstock | Pharmacol Rev | 1998 | 9755289 | No |
1623 | 5007 | 1669.0 | 164.14 | 54.7 | A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. | J R Le Gall, S Lemeshow, F Saulnier | JAMA | 1993 | 8254858 | Yes |
1624 | 3335 | 1667.5 | 218.37 | 109.2 | The structure of coping. | L I Pearlin, C Schooler | J Health Soc Behav | 1978 | 649936 | Yes |
1625 | 3335 | 1667.5 | 78.14 | 39.1 | Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. | Robert Visse, Hideaki Nagase | Circ Res | 2003 | 12730128 | No |
1626 | 1667 | 1667.0 | 52.73 | 52.7 | Metallothionein. | D H Hamer | Annu Rev Biochem | 1986 | 3527054 | No |
1627 | 1667 | 1667.0 | 26.92 | 26.9 | RNA-dependent DNA polymerase in virions of RNA tumour viruses. | D Baltimore | Nature | 1970 | 4316300 | Yes |
1628 | 1667 | 1667.0 | 32.36 | 32.4 | Cell cycle checkpoints: preventing an identity crisis. | S J Elledge | Science | 1996 | 8939848 | No |
1629 | 1667 | 1667.0 | 0.0 | 0.0 | Method for the determination of hexosamines in tissues. | N F Boas | J Biol Chem | 1953 | 13117829 | Yes |
1630 | 3329 | 1664.5 | 86.89 | 43.4 | Regulation of chromatin by histone modifications. | Andrew J Bannister, Tony Kouzarides | Cell Res | 2011 | 21321607 | No |
1631 | 11641 | 1663.0 | 390.84 | 55.8 | GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. | Gordon H Guyatt, Andrew D Oxman, Gunn E Vist, Regina Kunz, Yngve Falck-Ytter, Pablo Alonso-Coello, Holger J Schünemann | BMJ | 2008 | 18436948 | Yes |
1632 | 1661 | 1661.0 | 36.08 | 36.1 | The NCI60 human tumour cell line anticancer drug screen. | Robert H Shoemaker | Nat Rev Cancer | 2006 | 16990858 | No |
1633 | 1661 | 1661.0 | 52.74 | 52.7 | Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances. | Joseph J Volpe | Lancet Neurol | 2009 | 19081519 | No |
1634 | 6643 | 1660.8 | 152.92 | 38.2 | Use of T7 RNA polymerase to direct expression of cloned genes. | F W Studier, A H Rosenberg, J J Dunn, J W Dubendorff | Methods Enzymol | 1990 | 2199796 | Yes |
1635 | 3321 | 1660.5 | 83.76 | 41.9 | Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene. | M Grunstein, D S Hogness | Proc Natl Acad Sci U S A | 1975 | 1105573 | Yes |
1636 | 3320 | 1660.0 | 97.32 | 48.7 | An information-maximization approach to blind separation and blind deconvolution. | A J Bell, T J Sejnowski | Neural Comput | 1995 | 7584893 | Yes |
1637 | 1660 | 1660.0 | 66.38 | 66.4 | Sample size in qualitative research. | M Sandelowski | Res Nurs Health | 1995 | 7899572 | Yes |
1638 | 3320 | 1660.0 | 67.22 | 33.6 | A general framework for weighted gene co-expression network analysis. | Bin Zhang, Steve Horvath | Stat Appl Genet Mol Biol | 2005 | 16646834 | Yes |
1639 | 4978 | 1659.3 | 196.08 | 65.4 | The MOS 36-Item Short-Form Health Survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. | C A McHorney, J E Ware, A E Raczek | Med Care | 1993 | 8450681 | Yes |
1640 | 1659 | 1659.0 | 54.73 | 54.7 | Number of people with glaucoma worldwide. | H A Quigley | Br J Ophthalmol | 1996 | 8695555 | No |
1641 | 1659 | 1659.0 | 44.27 | 44.3 | Synergy, antagonism, and what the chequerboard puts between them. | F C Odds | J Antimicrob Chemother | 2003 | 12805255 | No |
1642 | 4976 | 1658.7 | 261.61 | 87.2 | Impact of Event Scale: a measure of subjective stress. | M Horowitz, N Wilner, W Alvarez | Psychosom Med | 1979 | 472086 | Yes |
1643 | 6633 | 1658.2 | 191.02 | 47.8 | Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. | B Biswal, F Z Yetkin, V M Haughton, J S Hyde | Magn Reson Med | 1995 | 8524021 | Yes |
1644 | 1658 | 1658.0 | 48.79 | 48.8 | Classification of inflammatory bowel disease. | J E Lennard-Jones | Scand J Gastroenterol Suppl | 1989 | 2617184 | Yes |
1645 | 8289 | 1657.8 | 64.94 | 13.0 | Studies Of Illness In The Aged. The Index Of Adl: A Standardized Measure Of Biological And Psychosocial Function. | S Katz, A B Ford, R W Moskowitz, B A Jackson, M W Jaffe | JAMA | 1963 | 14044222 | Yes |
1646 | 9944 | 1657.3 | 203.22 | 33.9 | Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. | A Fire, S Xu, M K Montgomery, S A Kostas, S E Driver, C C Mello | Nature | 1998 | 9486653 | Yes |
1647 | 3312 | 1656.0 | 58.86 | 29.4 | Method for the isolation of intact islets of Langerhans from the rat pancreas. | P E Lacy, M Kostianovsky | Diabetes | 1967 | 5333500 | Yes |
1648 | 6622 | 1655.5 | 261.92 | 65.5 | 16S ribosomal DNA amplification for phylogenetic study. | W G Weisburg, S M Barns, D A Pelletier, D J Lane | J Bacteriol | 1991 | 1987160 | Yes |
1649 | 1655 | 1655.0 | 37.09 | 37.1 | Introduction to NF-kappaB: players, pathways, perspectives. | T D Gilmore | Oncogene | 2006 | 17072321 | No |
1650 | 3310 | 1655.0 | 94.16 | 47.1 | Astrocytes: biology and pathology. | Michael V Sofroniew, Harry V Vinters | Acta Neuropathol | 2010 | 20012068 | No |
1651 | 1654 | 1654.0 | 67.88 | 67.9 | Responses to depression and their effects on the duration of depressive episodes. | S Nolen-Hoeksema | J Abnorm Psychol | 1991 | 1757671 | No |
1652 | 1654 | 1654.0 | 39.18 | 39.2 | Two pathogenetic types of endometrial carcinoma. | J V Bokhman | Gynecol Oncol | 1983 | 6822361 | Yes |
1653 | 1654 | 1654.0 | 41.92 | 41.9 | Neurotrophins and neuronal plasticity. | H Thoenen | Science | 1995 | 7570017 | No |
1654 | 1654 | 1654.0 | 0.0 | 0.0 | Axo-somatic and axo-dendritic synapses of the cerebral cortex: an electron microscope study. | E G Gray | J Anat | 1959 | 13829103 | Yes |
1655 | 1654 | 1654.0 | 0.0 | 0.0 | Note on the sampling error of the difference between correlated proportions or percentages. | Q McNEMAR | Psychometrika | 1947 | 20254758 | Yes |
1656 | 3304 | 1652.0 | 121.34 | 60.7 | The Carbon Monoxide-Binding Pigment Of Liver Microsomes. Ii. Solubilization, Purification, And Properties. | T Omura, R Sato | J Biol Chem | 1964 | 14209972 | Yes |
1657 | 1651 | 1651.0 | 80.74 | 80.7 | Measuring degree of physical dependence to tobacco smoking with reference to individualization of treatment. | K O Fagerström | Addict Behav | 1978 | 735910 | Yes |
1658 | 1651 | 1651.0 | 44.4 | 44.4 | An improved procedure for serum creatine phosphokinase determination. | S B Rosalki | J Lab Clin Med | 1967 | 4381359 | Yes |
1659 | 1650 | 1650.0 | 30.59 | 30.6 | Neuroblastoma: biological insights into a clinical enigma. | Garrett M Brodeur | Nat Rev Cancer | 2003 | 12612655 | No |
1660 | 1649 | 1649.0 | 31.37 | 31.4 | Switching and signaling at the telomere. | E H Blackburn | Cell | 2001 | 11572773 | No |
1661 | 3296 | 1648.0 | 122.87 | 61.4 | The mini-mental state examination: a comprehensive review. | T N Tombaugh, N J McIntyre | J Am Geriatr Soc | 1992 | 1512391 | No |
1662 | 1648 | 1648.0 | 67.36 | 67.4 | A comparison of the two one-sided tests procedure and the power approach for assessing the equivalence of average bioavailability. | D J Schuirmann | J Pharmacokinet Biopharm | 1987 | 3450848 | Yes |
1663 | 3295 | 1647.5 | 87.05 | 43.5 | Integrating QTL mapping and genome scans towards the characterization of candidate loci under parallel selection in the lake whitefish (Coregonus clupeaformis). | S M Rogers, L Bernatchez | Mol Ecol | 2005 | 15660930 | Yes |
1664 | 1647 | 1647.0 | 42.72 | 42.7 | Alpha-crystallin can function as a molecular chaperone. | J Horwitz | Proc Natl Acad Sci U S A | 1992 | 1438232 | Yes |
1665 | 1647 | 1647.0 | 46.61 | 46.6 | The many roles for fluorine in medicinal chemistry. | William K Hagmann | J Med Chem | 2008 | 18570365 | Yes |
1666 | 6582 | 1645.5 | 203.21 | 50.8 | The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. | S P Baker, B O'Neill, W Haddon, W B Long | J Trauma | 1974 | 4814394 | Yes |
1667 | 3291 | 1645.5 | 106.61 | 53.3 | Neurocircuitry of addiction. | George F Koob, Nora D Volkow | Neuropsychopharmacology | 2010 | 19710631 | No |
1668 | 1645 | 1645.0 | 45.46 | 45.5 | Turnover of inositol phospholipids and signal transduction. | Y Nishizuka | Science | 1984 | 6147898 | No |
1669 | 3289 | 1644.5 | 66.51 | 33.3 | Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. | Gary L Johnson, Razvan Lapadat | Science | 2002 | 12471242 | No |
1670 | 1644 | 1644.0 | 33.31 | 33.3 | DNA in a material world. | Nadrian C Seeman | Nature | 2003 | 12540916 | No |
1671 | 1644 | 1644.0 | 39.2 | 39.2 | The failing heart--an engine out of fuel. | Stefan Neubauer | N Engl J Med | 2007 | 17360992 | No |
1672 | 1643 | 1643.0 | 45.05 | 45.0 | The origins of the developmental origins theory. | D J P Barker | J Intern Med | 2007 | 17444880 | No |
1673 | 3286 | 1643.0 | 130.58 | 65.3 | The Emerging Hallmarks of Cancer Metabolism. | Natalya N Pavlova, Craig B Thompson | Cell Metab | 2016 | 26771115 | No |
1674 | 3285 | 1642.5 | 65.96 | 33.0 | Upstream and downstream of mTOR. | Nissim Hay, Nahum Sonenberg | Genes Dev | 2004 | 15314020 | No |
1675 | 1642 | 1642.0 | 49.02 | 49.0 | Extracellular ATP: effects, sources and fate. | J L Gordon | Biochem J | 1986 | 3006665 | No |
1676 | 1642 | 1642.0 | 19.62 | 19.6 | Amino acid difference formula to help explain protein evolution. | R Grantham | Science | 1974 | 4843792 | Yes |
1677 | 3284 | 1642.0 | 71.15 | 35.6 | Protein structure comparison by alignment of distance matrices. | L Holm, C Sander | J Mol Biol | 1993 | 8377180 | Yes |
1678 | 1642 | 1642.0 | 50.84 | 50.8 | Stress and disorders of the stress system. | George P Chrousos | Nat Rev Endocrinol | 2009 | 19488073 | No |
1679 | 4926 | 1642.0 | 209.97 | 70.0 | The behaviour change wheel: a new method for characterising and designing behaviour change interventions. | Susan Michie, Maartje M van Stralen, Robert West | Implement Sci | 2011 | 21513547 | No |
1680 | 1641 | 1641.0 | 62.62 | 62.6 | Probiotics in man and animals. | R Fuller | J Appl Bacteriol | 1989 | 2666378 | No |
1681 | 1641 | 1641.0 | 46.37 | 46.4 | Semiempirical hybrid density functional with perturbative second-order correlation. | Stefan Grimme | J Chem Phys | 2006 | 16438568 | Yes |
1682 | 1640 | 1640.0 | 40.36 | 40.4 | Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia. | Shitij Kapur | Am J Psychiatry | 2003 | 12505794 | No |
1683 | 1640 | 1640.0 | 46.84 | 46.8 | Optimization of parameters for semiempirical methods V: modification of NDDO approximations and application to 70 elements. | James J P Stewart | J Mol Model | 2007 | 17828561 | Yes |
1684 | 1640 | 1640.0 | 53.15 | 53.1 | The global impact of pre-eclampsia and eclampsia. | Lelia Duley | Semin Perinatol | 2009 | 19464502 | No |
1685 | 1639 | 1639.0 | 53.79 | 53.8 | Archaea in coastal marine environments. | E F DeLong | Proc Natl Acad Sci U S A | 1992 | 1608980 | Yes |
1686 | 1638 | 1638.0 | 32.41 | 32.4 | Simple memory: a theory for archicortex. | D Marr | Philos Trans R Soc Lond B Biol Sci | 1971 | 4399412 | Yes |
1687 | 1638 | 1638.0 | 30.47 | 30.5 | Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy. | M G Gustafsson | J Microsc | 2000 | 10810003 | Yes |
1688 | 3276 | 1638.0 | 99.38 | 49.7 | The benefits of being present: mindfulness and its role in psychological well-being. | Kirk Warren Brown, Richard M Ryan | J Pers Soc Psychol | 2003 | 12703651 | Yes |
1689 | 1638 | 1638.0 | 37.48 | 37.5 | In vivo near-infrared fluorescence imaging. | John V Frangioni | Curr Opin Chem Biol | 2003 | 14580568 | No |
1690 | 1638 | 1638.0 | 35.53 | 35.5 | Hematopoietic stem-cell transplantation. | Edward A Copelan | N Engl J Med | 2006 | 16641398 | No |
1691 | 3276 | 1638.0 | 91.25 | 45.6 | A perspective on cancer cell metastasis. | Christine L Chaffer, Robert A Weinberg | Science | 2011 | 21436443 | No |
1692 | 1637 | 1637.0 | 58.58 | 58.6 | Dual-task interference in simple tasks: data and theory. | H Pashler | Psychol Bull | 1994 | 7972591 | No |
1693 | 1637 | 1637.0 | 35.43 | 35.4 | An approximately unbiased test of phylogenetic tree selection. | Hidetoshi Shimodaira | Syst Biol | 2002 | 12079646 | Yes |
1694 | 3274 | 1637.0 | 74.77 | 37.4 | Human mesenchymal stem cells modulate allogeneic immune cell responses. | Sudeepta Aggarwal, Mark F Pittenger | Blood | 2005 | 15494428 | Yes |
1695 | 1636 | 1636.0 | 34.68 | 34.7 | Neuronal calcium signaling. | M J Berridge | Neuron | 1998 | 9697848 | No |
1696 | 1636 | 1636.0 | 38.2 | 38.2 | A simple fluorimetric method for the estimation of free 11-hydroxycorticoids in human plasma. | D Mattingly | J Clin Pathol | 1962 | 14471419 | Yes |
1697 | 3267 | 1633.5 | 212.18 | 106.1 | A clinical method of functional assessment of the shoulder. | C R Constant, A H Murley | Clin Orthop Relat Res | 1987 | 3791738 | Yes |
1698 | 1633 | 1633.0 | 30.57 | 30.6 | Germinal centers. | I C MacLennan | Annu Rev Immunol | 1994 | 8011279 | No |
1699 | 1632 | 1632.0 | 56.45 | 56.5 | Frontal-subcortical circuits and human behavior. | J L Cummings | Arch Neurol | 1993 | 8352676 | No |
1700 | 1632 | 1632.0 | 29.16 | 29.2 | Maximum-likelihood density modification. | T C Terwilliger | Acta Crystallogr D Biol Crystallogr | 2000 | 10944333 | Yes |
1701 | 1631 | 1631.0 | 71.07 | 71.1 | Neurogenetic adaptive mechanisms in alcoholism. | C R Cloninger | Science | 1987 | 2882604 | Yes |
1702 | 3262 | 1631.0 | 77.12 | 38.6 | Adipose tissue as an endocrine organ. | Erin E Kershaw, Jeffrey S Flier | J Clin Endocrinol Metab | 2004 | 15181022 | No |
1703 | 1630 | 1630.0 | 34.84 | 34.8 | Bone morphogenetic proteins: multifunctional regulators of vertebrate development. | B L Hogan | Genes Dev | 1996 | 8682290 | No |
1704 | 1630 | 1630.0 | 38.51 | 38.5 | Five rules for the evolution of cooperation. | Martin A Nowak | Science | 2006 | 17158317 | No |
1705 | 9776 | 1629.3 | 226.72 | 37.8 | Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. | D J Slamon, G M Clark, S G Wong, W J Levin, A Ullrich, W L McGuire | Science | 1987 | 3798106 | Yes |
1706 | 1629 | 1629.0 | 58.25 | 58.2 | Cell damage in the brain: a speculative synthesis. | B K Siesjö | J Cereb Blood Flow Metab | 1981 | 6276420 | No |
1707 | 1629 | 1629.0 | 72.48 | 72.5 | Mood and memory. | G H Bower | Am Psychol | 1981 | 7224324 | Yes |
1708 | 1629 | 1629.0 | 40.29 | 40.3 | Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. | M J Meaney | Annu Rev Neurosci | 2001 | 11520931 | No |
1709 | 3257 | 1628.5 | 88.59 | 44.3 | Bronchopulmonary dysplasia. | A H Jobe, E Bancalari | Am J Respir Crit Care Med | 2001 | 11401896 | No |
1710 | 1628 | 1628.0 | 49.21 | 49.2 | Stress signalling pathways that impair prefrontal cortex structure and function. | Amy F T Arnsten | Nat Rev Neurosci | 2009 | 19455173 | No |
1711 | 13012 | 1626.5 | 377.76 | 47.2 | The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. | Ziad S Nasreddine, Natalie A Phillips, Valérie Bédirian, Simon Charbonneau, Victor Whitehead, Isabelle Collin, Jeffrey L Cummings, Howard Chertkow | J Am Geriatr Soc | 2005 | 15817019 | Yes |
1712 | 1626 | 1626.0 | 23.03 | 23.0 | Structural considerations in the interaction of DNA and acridines. | L S Lerman | J Mol Biol | 1961 | 13761054 | Yes |
1713 | 6503 | 1625.8 | 280.67 | 70.2 | A rating scale for mania: reliability, validity and sensitivity. | R C Young, J T Biggs, V E Ziegler, D A Meyer | Br J Psychiatry | 1978 | 728692 | Yes |
1714 | 1625 | 1625.0 | 41.66 | 41.7 | Understanding biofilm resistance to antibacterial agents. | David Davies | Nat Rev Drug Discov | 2003 | 12563302 | No |
1715 | 4875 | 1625.0 | 147.35 | 49.1 | Simultaneous inference in general parametric models. | Torsten Hothorn, Frank Bretz, Peter Westfall | Biom J | 2008 | 18481363 | No |
1716 | 1624 | 1624.0 | 42.56 | 42.6 | Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp. | D A Dougherty | Science | 1996 | 8539615 | No |
1717 | 1624 | 1624.0 | 46.34 | 46.3 | The basal ganglia: focused selection and inhibition of competing motor programs. | J W Mink | Prog Neurobiol | 1996 | 9004351 | No |
1718 | 1623 | 1623.0 | 45.24 | 45.2 | Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction. | B Hille | J Gen Physiol | 1977 | 300786 | Yes |
1719 | 1623 | 1623.0 | 33.1 | 33.1 | Structural features in eukaryotic mRNAs that modulate the initiation of translation. | M Kozak | J Biol Chem | 1991 | 1939050 | No |
1720 | 1623 | 1623.0 | 58.11 | 58.1 | The linear-quadratic formula and progress in fractionated radiotherapy. | J F Fowler | Br J Radiol | 1989 | 2670032 | No |
1721 | 3245 | 1622.5 | 96.77 | 48.4 | Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltons. | M Karas, F Hillenkamp | Anal Chem | 1988 | 3239801 | Yes |
1722 | 3245 | 1622.5 | 109.64 | 54.8 | Neutrophil recruitment and function in health and inflammation. | Elzbieta Kolaczkowska, Paul Kubes | Nat Rev Immunol | 2013 | 23435331 | No |
1723 | 1622 | 1622.0 | 46.06 | 46.1 | Fluorescence energy transfer as a spectroscopic ruler. | L Stryer | Annu Rev Biochem | 1978 | 354506 | No |
1724 | 1622 | 1622.0 | 50.87 | 50.9 | Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage. | D W Choi | Trends Neurosci | 1988 | 2469166 | No |
1725 | 1622 | 1622.0 | 34.24 | 34.2 | The caveolae membrane system. | R G Anderson | Annu Rev Biochem | 1998 | 9759488 | No |
1726 | 3244 | 1622.0 | 84.98 | 42.5 | Early identification of refractory epilepsy. | P Kwan, M J Brodie | N Engl J Med | 2000 | 10660394 | Yes |
1727 | 1620 | 1620.0 | 27.86 | 27.9 | Cell cycle checkpoint signaling through the ATM and ATR kinases. | R T Abraham | Genes Dev | 2001 | 11544175 | No |
1728 | 3239 | 1619.5 | 86.16 | 43.1 | Molecular mechanisms of long noncoding RNAs. | Kevin C Wang, Howard Y Chang | Mol Cell | 2011 | 21925379 | No |
1729 | 1619 | 1619.0 | 47.33 | 47.3 | Metalloproteinases and their inhibitors in matrix remodeling. | L M Matrisian | Trends Genet | 1990 | 2132731 | No |
1730 | 3237 | 1618.5 | 76.62 | 38.3 | Rapid and sensitive protein similarity searches. | D J Lipman, W R Pearson | Science | 1985 | 2983426 | Yes |
1731 | 6474 | 1618.5 | 213.99 | 53.5 | Common method biases in behavioral research: a critical review of the literature and recommended remedies. | Philip M Podsakoff, Scott B MacKenzie, Jeong-Yeon Lee, Nathan P Podsakoff | J Appl Psychol | 2003 | 14516251 | No |
1732 | 4855 | 1618.3 | 94.84 | 31.6 | T-Coffee: A novel method for fast and accurate multiple sequence alignment. | C Notredame, D G Higgins, J Heringa | J Mol Biol | 2000 | 10964570 | Yes |
1733 | 1618 | 1618.0 | 41.17 | 41.2 | The importance of the ratio of omega-6/omega-3 essential fatty acids. | A P Simopoulos | Biomed Pharmacother | 2002 | 12442909 | No |
1734 | 1617 | 1617.0 | 57.81 | 57.8 | Aging, natural death, and the compression of morbidity. | J F Fries | N Engl J Med | 1980 | 7383070 | Yes |
1735 | 4850 | 1616.7 | 176.98 | 59.0 | Multiple imputation using chained equations: Issues and guidance for practice. | Ian R White, Patrick Royston, Angela M Wood | Stat Med | 2011 | 21225900 | Yes |
1736 | 9699 | 1616.5 | 335.04 | 55.8 | Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. | L C Green, D A Wagner, J Glogowski, P L Skipper, J S Wishnok, S R Tannenbaum | Anal Biochem | 1982 | 7181105 | Yes |
1737 | 1616 | 1616.0 | 36.96 | 37.0 | VLA proteins in the integrin family: structures, functions, and their role on leukocytes. | M E Hemler | Annu Rev Immunol | 1990 | 2188667 | No |
1738 | 1616 | 1616.0 | 0.0 | 0.0 | Discharge patterns and functional organization of mammalian retina. | S W Kuffler | J Neurophysiol | 1953 | 13035466 | Yes |
1739 | 1615 | 1615.0 | 72.04 | 72.0 | The structure and properties of the sense of coherence scale. | A Antonovsky | Soc Sci Med | 1993 | 8480217 | Yes |
1740 | 3229 | 1614.5 | 89.09 | 44.5 | Diarrheagenic Escherichia coli. | J P Nataro, J B Kaper | Clin Microbiol Rev | 1998 | 9457432 | No |
1741 | 1614 | 1614.0 | 58.53 | 58.5 | Interhemispheric differences in the localization of psychological processes in man. | B Milner | Br Med Bull | 1971 | 4937273 | No |
1742 | 3228 | 1614.0 | 95.18 | 47.6 | Unified approach for molecular dynamics and density-functional theory. | R Car, M Parrinello | Phys Rev Lett | 1985 | 10032153 | Yes |
1743 | 1612 | 1612.0 | 36.91 | 36.9 | Cellular oncogenes and retroviruses. | J M Bishop | Annu Rev Biochem | 1983 | 6351725 | No |
1744 | 1612 | 1612.0 | 30.5 | 30.5 | Protein kinases--the major drug targets of the twenty-first century? | Philip Cohen | Nat Rev Drug Discov | 2002 | 12120282 | No |
1745 | 1612 | 1612.0 | 45.35 | 45.4 | Understanding organofluorine chemistry. An introduction to the C-F bond. | David O'Hagan | Chem Soc Rev | 2008 | 18197347 | No |
1746 | 1609 | 1609.0 | 51.05 | 51.0 | Cellular defenses against damage from reactive oxygen species. | B P Yu | Physiol Rev | 1994 | 8295932 | No |
1747 | 1609 | 1609.0 | 49.5 | 49.5 | Apoptosis in cancer: from pathogenesis to treatment. | Rebecca S Y Wong | J Exp Clin Cancer Res | 2011 | 21943236 | No |
1748 | 1609 | 1609.0 | 220.54 | 220.5 | COVID-19 and mental health: A review of the existing literature. | Ravi Philip Rajkumar | Asian J Psychiatr | 2020 | 32302935 | Yes |
1749 | 3217 | 1608.5 | 62.58 | 31.3 | Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. | M E Greenberg, E B Ziff | Nature | 1984 | 6090941 | Yes |
1750 | 3217 | 1608.5 | 152.47 | 76.2 | Making sense of Cronbach's alpha. | Mohsen Tavakol, Reg Dennick | Int J Med Educ | 2011 | 28029643 | No |
1751 | 1608 | 1608.0 | 40.69 | 40.7 | External validity of randomised controlled trials: "to whom do the results of this trial apply?". | Peter M Rothwell | Lancet | 2005 | 15639683 | Yes |
1752 | 11254 | 1607.7 | 335.82 | 48.0 | AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility. | Garrett M Morris, Ruth Huey, William Lindstrom, Michel F Sanner, Richard K Belew, David S Goodsell, Arthur J Olson | J Comput Chem | 2009 | 19399780 | Yes |
1753 | 1607 | 1607.0 | 45.5 | 45.5 | Ionic dependence of glutamate neurotoxicity. | D W Choi | J Neurosci | 1987 | 2880938 | Yes |
1754 | 1607 | 1607.0 | 57.21 | 57.2 | Cytokines in inflammatory bowel disease. | Markus F Neurath | Nat Rev Immunol | 2014 | 24751956 | No |
1755 | 1606 | 1606.0 | 39.48 | 39.5 | Tumor necrosis factor (TNF). | L J Old | Science | 1985 | 2413547 | Yes |
1756 | 1605 | 1605.0 | 56.4 | 56.4 | The case-crossover design: a method for studying transient effects on the risk of acute events. | M Maclure | Am J Epidemiol | 1991 | 1985444 | Yes |
1757 | 3210 | 1605.0 | 67.23 | 33.6 | The Ki-67 protein: from the known and the unknown. | T Scholzen, J Gerdes | J Cell Physiol | 2000 | 10653597 | No |
1758 | 3209 | 1604.5 | 81.65 | 40.8 | ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins. | Markus Wiederstein, Manfred J Sippl | Nucleic Acids Res | 2007 | 17517781 | Yes |
1759 | 3208 | 1604.0 | 114.03 | 57.0 | Measuring emotion: the Self-Assessment Manikin and the Semantic Differential. | M M Bradley, P J Lang | J Behav Ther Exp Psychiatry | 1994 | 7962581 | Yes |
1760 | 1604 | 1604.0 | 44.58 | 44.6 | Multiple imputation of discrete and continuous data by fully conditional specification. | Stef van Buuren | Stat Methods Med Res | 2007 | 17621469 | Yes |
1761 | 1602 | 1602.0 | 0.0 | 0.0 | Cerebral blood flow and oxygen consumption in man. | N A Lassen | Physiol Rev | 1959 | 13645234 | Yes |
1762 | 1602 | 1602.0 | 30.96 | 31.0 | The microRNA Registry. | Sam Griffiths-Jones | Nucleic Acids Res | 2004 | 14681370 | Yes |
1763 | 3203 | 1601.5 | 112.92 | 56.5 | Avoiding false positives with PCR. | S Kwok, R Higuchi | Nature | 1989 | 2716852 | Yes |
1764 | 1601 | 1601.0 | 45.94 | 45.9 | The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system function. | R R Llinás | Science | 1988 | 3059497 | No |
1765 | 1601 | 1601.0 | 33.41 | 33.4 | The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept. | A G Pearse | J Histochem Cytochem | 1969 | 4143745 | No |
1766 | 3202 | 1601.0 | 64.05 | 32.0 | The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat. | J O'Keefe, J Dostrovsky | Brain Res | 1971 | 5124915 | Yes |
1767 | 1601 | 1601.0 | 39.05 | 39.0 | Recognition of errors in three-dimensional structures of proteins. | M J Sippl | Proteins | 1993 | 8108378 | Yes |
1768 | 1601 | 1601.0 | 41.92 | 41.9 | Task switching. | Stephen Monsell | Trends Cogn Sci | 2003 | 12639695 | Yes |
1769 | 1601 | 1601.0 | 0.0 | 0.0 | Antigen-antibody reactions in gels. IV. Types of reactions in coordinated systems of diffusion. | O Ouchterlony | Acta Pathol Microbiol Scand | 1953 | 13079779 | Yes |
1770 | 1601 | 1601.0 | 0.0 | 0.0 | Application of a Theory of Enzyme Specificity to Protein Synthesis. | D E Koshland | Proc Natl Acad Sci U S A | 1958 | 16590179 | Yes |
1771 | 1600 | 1600.0 | 31.67 | 31.7 | An analysis of vertebrate mRNA sequences: intimations of translational control. | M Kozak | J Cell Biol | 1991 | 1955461 | No |
1772 | 3200 | 1600.0 | 67.61 | 33.8 | Inhibitors of mammalian G1 cyclin-dependent kinases. | C J Sherr, J M Roberts | Genes Dev | 1995 | 7758941 | No |
1773 | 3200 | 1600.0 | 156.24 | 78.1 | Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees. | Ivica Letunic, Peer Bork | Nucleic Acids Res | 2016 | 27095192 | Yes |
1774 | 4799 | 1599.7 | 114.31 | 38.1 | Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets. | Claus Lindbjerg Andersen, Jens Ledet Jensen, Torben Falck Ørntoft | Cancer Res | 2004 | 15289330 | Yes |
1775 | 3199 | 1599.5 | 66.08 | 33.0 | Signaling to NF-kappaB. | Matthew S Hayden, Sankar Ghosh | Genes Dev | 2004 | 15371334 | No |
1776 | 1599 | 1599.0 | 40.93 | 40.9 | Molecular biology of prion diseases. | S B Prusiner | Science | 1991 | 1675487 | No |
1777 | 4797 | 1599.0 | 133.05 | 44.4 | Cell death: the significance of apoptosis. | A H Wyllie, J F Kerr, A R Currie | Int Rev Cytol | 1980 | 7014501 | No |
1778 | 3198 | 1599.0 | 61.73 | 30.9 | Automated MAD and MIR structure solution. | T C Terwilliger, J Berendzen | Acta Crystallogr D Biol Crystallogr | 1999 | 10089316 | Yes |
1779 | 1598 | 1598.0 | 52.11 | 52.1 | Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue'). | M N Marsh | Gastroenterology | 1992 | 1727768 | No |
1780 | 1598 | 1598.0 | 34.22 | 34.2 | On finding all suboptimal foldings of an RNA molecule. | M Zuker | Science | 1989 | 2468181 | No |
1781 | 1598 | 1598.0 | 52.97 | 53.0 | Asthma phenotypes: the evolution from clinical to molecular approaches. | Sally E Wenzel | Nat Med | 2012 | 22561835 | No |
1782 | 3194 | 1597.0 | 88.47 | 44.2 | Polyamines. | C W Tabor, H Tabor | Annu Rev Biochem | 1984 | 6206782 | No |
1783 | 1597 | 1597.0 | 72.76 | 72.8 | Measurement of health state utilities for economic appraisal. | G W Torrance | J Health Econ | 1986 | 10311607 | No |
1784 | 1597 | 1597.0 | 36.46 | 36.5 | Getting formal with dopamine and reward. | Wolfram Schultz | Neuron | 2002 | 12383780 | No |
1785 | 1597 | 1597.0 | 36.19 | 36.2 | Thiazolidinediones. | Hannele Yki-Järvinen | N Engl J Med | 2004 | 15356308 | No |
1786 | 1597 | 1597.0 | 45.11 | 45.1 | Gold-catalyzed organic reactions. | A Stephen K Hashmi | Chem Rev | 2007 | 17580975 | Yes |
1787 | 3191 | 1595.5 | 83.32 | 41.7 | Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. | D B Dill, D L Costill | J Appl Physiol | 1974 | 4850854 | Yes |
1788 | 1595 | 1595.0 | 36.66 | 36.7 | A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. | D A Gewirtz | Biochem Pharmacol | 1999 | 10075079 | No |
1789 | 1595 | 1595.0 | 36.36 | 36.4 | Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. | S C Manolagas | Endocr Rev | 2000 | 10782361 | No |
1790 | 1595 | 1595.0 | 36.67 | 36.7 | Neurovascular regulation in the normal brain and in Alzheimer's disease. | Costantino Iadecola | Nat Rev Neurosci | 2004 | 15100718 | No |
1791 | 1594 | 1594.0 | 28.74 | 28.7 | Altering the genome by homologous recombination. | M R Capecchi | Science | 1989 | 2660260 | No |
1792 | 1593 | 1593.0 | 55.2 | 55.2 | The self-medication hypothesis of substance use disorders: a reconsideration and recent applications. | E J Khantzian | Harv Rev Psychiatry | 1997 | 9385000 | No |
1793 | 1593 | 1593.0 | 38.96 | 39.0 | The corticosteroid receptor hypothesis of depression. | F Holsboer | Neuropsychopharmacology | 2000 | 11027914 | No |
1794 | 3185 | 1592.5 | 77.53 | 38.8 | A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes. | S Tabor, C C Richardson | Proc Natl Acad Sci U S A | 1985 | 3156376 | Yes |
1795 | 3185 | 1592.5 | 91.62 | 45.8 | Oxidative stress, glutamate, and neurodegenerative disorders. | J T Coyle, P Puttfarcken | Science | 1993 | 7901908 | No |
1796 | 1592 | 1592.0 | 70.8 | 70.8 | The contribution of low birth weight to infant mortality and childhood morbidity. | M C McCormick | N Engl J Med | 1985 | 3880598 | No |
1797 | 1592 | 1592.0 | 44.21 | 44.2 | Extended-spectrum beta-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat. | P A Bradford | Clin Microbiol Rev | 2001 | 11585791 | No |
1798 | 1591 | 1591.0 | 35.64 | 35.6 | Hypertrophic cardiomyopathy: a systematic review. | Barry J Maron | JAMA | 2002 | 11886323 | No |
1799 | 1590 | 1590.0 | 56.74 | 56.7 | Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons. | P Holzer | Pharmacol Rev | 1991 | 1852779 | No |
1800 | 1590 | 1590.0 | 31.34 | 31.3 | Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing. | D I Svergun | Biophys J | 1999 | 10354416 | Yes |
1801 | 1590 | 1590.0 | 80.27 | 80.3 | Hydrogel: Preparation, characterization, and applications: A review. | Enas M Ahmed | J Adv Res | 2015 | 25750745 | No |
1802 | 1589 | 1589.0 | 48.77 | 48.8 | Efficient analysis of experimental observations. | W J Dixon | Annu Rev Pharmacol Toxicol | 1980 | 7387124 | Yes |
1803 | 1589 | 1589.0 | 48.36 | 48.4 | Chlorophyll fluorescence: a probe of photosynthesis in vivo. | Neil R Baker | Annu Rev Plant Biol | 2008 | 18444897 | No |
1804 | 3176 | 1588.0 | 66.12 | 33.1 | Fitting a mixture model by expectation maximization to discover motifs in biopolymers. | T L Bailey, C Elkan | Proc Int Conf Intell Syst Mol Biol | 1994 | 7584402 | Yes |
1805 | 1588 | 1588.0 | 41.88 | 41.9 | Precision mapping of quantitative trait loci. | Z B Zeng | Genetics | 1994 | 8013918 | Yes |
1806 | 3172 | 1586.0 | 116.5 | 58.2 | A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms. | J A Horne, O Ostberg | Int J Chronobiol | 1976 | 1027738 | Yes |
1807 | 1586 | 1586.0 | 51.8 | 51.8 | Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection. | W H Oldendorf | Am J Physiol | 1971 | 5124307 | Yes |
1808 | 1586 | 1586.0 | 35.52 | 35.5 | The proto-oncogene Bcl-2 and its role in regulating apoptosis. | G Kroemer | Nat Med | 1997 | 9176486 | No |
1809 | 1585 | 1585.0 | 65.34 | 65.3 | Regulation of noradrenaline release by presynaptic receptor systems. | K Starke | Rev Physiol Biochem Pharmacol | 1977 | 14389 | No |
1810 | 3170 | 1585.0 | 97.21 | 48.6 | Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. | D S Bredt, S H Snyder | Proc Natl Acad Sci U S A | 1990 | 1689048 | Yes |
1811 | 1585 | 1585.0 | 35.93 | 35.9 | The genetical evolution of social behaviour. II. | W D Hamilton | J Theor Biol | 1964 | 5875340 | Yes |
1812 | 1585 | 1585.0 | 34.33 | 34.3 | Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. | G L Semenza | Annu Rev Cell Dev Biol | 1999 | 10611972 | No |
1813 | 1584 | 1584.0 | 29.45 | 29.4 | How cells read TGF-beta signals. | J Massagué | Nat Rev Mol Cell Biol | 2000 | 11252892 | No |
1814 | 4747 | 1582.3 | 115.74 | 38.6 | Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. | Earl S Ford, Wayne H Giles, William H Dietz | JAMA | 2002 | 11790215 | Yes |
1815 | 3164 | 1582.0 | 70.53 | 35.3 | Lipopolysaccharide endotoxins. | Christian R H Raetz, Chris Whitfield | Annu Rev Biochem | 2002 | 12045108 | No |
1816 | 1582 | 1582.0 | 44.15 | 44.1 | Dithiothreitol, A New Protective Reagent For Sh Groups. | W W Cleland | Biochemistry | 1964 | 14192894 | Yes |
1817 | 1581 | 1581.0 | 52.33 | 52.3 | Which elements are excited in electrical stimulation of mammalian central nervous system: a review. | J B Ranck | Brain Res | 1975 | 1102064 | No |
1818 | 1580 | 1580.0 | 47.55 | 47.5 | Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance. | L Bravo | Nutr Rev | 1998 | 9838798 | No |
1819 | 1580 | 1580.0 | 104.44 | 104.4 | The Global Epidemic of the Metabolic Syndrome. | Mohammad G Saklayen | Curr Hypertens Rep | 2018 | 29480368 | No |
1820 | 3158 | 1579.0 | 174.28 | 87.1 | Natural Products as Sources of New Drugs from 1981 to 2014. | David J Newman, Gordon M Cragg | J Nat Prod | 2016 | 26852623 | No |
1821 | 1578 | 1578.0 | 48.58 | 48.6 | The role of the amygdala in fear and anxiety. | M Davis | Annu Rev Neurosci | 1992 | 1575447 | No |
1822 | 1578 | 1578.0 | 31.32 | 31.3 | Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy. | R K Jain | Nat Med | 2001 | 11533692 | No |
1823 | 3156 | 1578.0 | 62.41 | 31.2 | NF-kappaB regulation in the immune system. | Qiutang Li, Inder M Verma | Nat Rev Immunol | 2002 | 12360211 | No |
1824 | 1578 | 1578.0 | 37.37 | 37.4 | The blood-brain barrier: bottleneck in brain drug development. | William M Pardridge | NeuroRx | 2005 | 15717053 | No |
1825 | 17347 | 1577.0 | 548.65 | 49.9 | A new equation to estimate glomerular filtration rate. | Andrew S Levey, Lesley A Stevens, Christopher H Schmid, Yaping Lucy Zhang, Alejandro F Castro, Harold I Feldman, John W Kusek, Paul Eggers, Frederick Van Lente, Tom Greene, Josef Coresh | Ann Intern Med | 2009 | 19414839 | Yes |
1826 | 4728 | 1576.0 | 129.01 | 43.0 | Dating of the human-ape splitting by a molecular clock of mitochondrial DNA. | M Hasegawa, H Kishino, T Yano | J Mol Evol | 1985 | 3934395 | Yes |
1827 | 1576 | 1576.0 | 34.02 | 34.0 | Mechanisms of bone metastasis. | G David Roodman | N Engl J Med | 2004 | 15084698 | No |
1828 | 1575 | 1575.0 | 42.61 | 42.6 | The complete general secretory pathway in gram-negative bacteria. | A P Pugsley | Microbiol Rev | 1993 | 8096622 | No |
1829 | 1575 | 1575.0 | 29.97 | 30.0 | Immunosuppressive networks in the tumour environment and their therapeutic relevance. | Weiping Zou | Nat Rev Cancer | 2005 | 15776005 | No |
1830 | 1575 | 1575.0 | 30.42 | 30.4 | Regulatory T cells, tumour immunity and immunotherapy. | Weiping Zou | Nat Rev Immunol | 2006 | 16557261 | No |
1831 | 1575 | 1575.0 | 36.63 | 36.6 | Insulin and insulin-like growth factor signalling in neoplasia. | Michael Pollak | Nat Rev Cancer | 2008 | 19029956 | No |
1832 | 4722 | 1574.0 | 115.36 | 38.5 | Two-photon laser scanning fluorescence microscopy. | W Denk, J H Strickler, W W Webb | Science | 1990 | 2321027 | Yes |
1833 | 1574 | 1574.0 | 52.48 | 52.5 | Biology of interleukin 1. | C A Dinarello | FASEB J | 1988 | 3277884 | No |
1834 | 1574 | 1574.0 | 44.98 | 45.0 | Glycosphingolipids in cellular interaction, differentiation, and oncogenesis. | S Hakomori | Annu Rev Biochem | 1981 | 7023369 | No |
1835 | 3148 | 1574.0 | 98.63 | 49.3 | Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. | G R Gibson, M B Roberfroid | J Nutr | 1995 | 7782892 | No |
1836 | 3148 | 1574.0 | 64.71 | 32.4 | Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions. | E Krissinel, K Henrick | Acta Crystallogr D Biol Crystallogr | 2004 | 15572779 | Yes |
1837 | 3147 | 1573.5 | 92.38 | 46.2 | Density functionals with broad applicability in chemistry. | Yan Zhao, Donald G Truhlar | Acc Chem Res | 2008 | 18186612 | Yes |
1838 | 1573 | 1573.0 | 40.08 | 40.1 | Aspergillus fumigatus and aspergillosis. | J P Latgé | Clin Microbiol Rev | 1999 | 10194462 | No |
1839 | 3146 | 1573.0 | 88.11 | 44.1 | Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research. | Sally S Dickerson, Margaret E Kemeny | Psychol Bull | 2004 | 15122924 | Yes |
1840 | 3145 | 1572.5 | 127.17 | 63.6 | Methods for the thematic synthesis of qualitative research in systematic reviews. | James Thomas, Angela Harden | BMC Med Res Methodol | 2008 | 18616818 | Yes |
1841 | 3145 | 1572.5 | 99.91 | 50.0 | Palladium-catalyzed ligand-directed C-H functionalization reactions. | Thomas W Lyons, Melanie S Sanford | Chem Rev | 2010 | 20078038 | No |
1842 | 1572 | 1572.0 | 41.57 | 41.6 | Molecular bases of the acute coronary syndromes. | P Libby | Circulation | 1995 | 7758192 | No |
1843 | 1572 | 1572.0 | 37.8 | 37.8 | HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy. | J M Coffin | Science | 1995 | 7824947 | Yes |
1844 | 1572 | 1572.0 | 29.67 | 29.7 | Intrinsically unstructured proteins. | Peter Tompa | Trends Biochem Sci | 2002 | 12368089 | No |
1845 | 3143 | 1571.5 | 61.3 | 30.6 | The evolutionary fate and consequences of duplicate genes. | M Lynch, J S Conery | Science | 2000 | 11073452 | No |
1846 | 3142 | 1571.0 | 68.67 | 34.3 | Neurotrophins: roles in neuronal development and function. | E J Huang, L F Reichardt | Annu Rev Neurosci | 2001 | 11520916 | No |
1847 | 3142 | 1571.0 | 57.95 | 29.0 | The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. | Michael H Glickman, Aaron Ciechanover | Physiol Rev | 2002 | 11917093 | No |
1848 | 1571 | 1571.0 | 39.07 | 39.1 | Marine viruses--major players in the global ecosystem. | Curtis A Suttle | Nat Rev Microbiol | 2007 | 17853907 | No |
1849 | 1570 | 1570.0 | 66.78 | 66.8 | Structure, Function, and Evolution of Coronavirus Spike Proteins. | Fang Li | Annu Rev Virol | 2016 | 27578435 | No |
1850 | 3139 | 1569.5 | 96.95 | 48.5 | Oxidative stress and diabetic complications. | Ferdinando Giacco, Michael Brownlee | Circ Res | 2010 | 21030723 | No |
1851 | 1569 | 1569.0 | 59.96 | 60.0 | Local effector functions of capsaicin-sensitive sensory nerve endings: involvement of tachykinins, calcitonin gene-related peptide and other neuropeptides. | P Holzer | Neuroscience | 1988 | 3288903 | No |
1852 | 3136 | 1568.0 | 60.52 | 30.3 | Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. | O Tetsu, F McCormick | Nature | 1999 | 10201372 | Yes |
1853 | 1567 | 1567.0 | 106.58 | 106.6 | Anterior acromioplasty for the chronic impingement syndrome in the shoulder: a preliminary report. | C S Neer | J Bone Joint Surg Am | 1972 | 5054450 | Yes |
1854 | 1565 | 1565.0 | 0.0 | 0.0 | A modified spectrophotometric determination of chymotrypsin, trypsin, and thrombin. | B C Hummel | Can J Biochem Physiol | 1959 | 14405350 | Yes |
1855 | 3129 | 1564.5 | 67.89 | 33.9 | Microtubules as a target for anticancer drugs. | Mary Ann Jordan, Leslie Wilson | Nat Rev Cancer | 2004 | 15057285 | No |
1856 | 1564 | 1564.0 | 33.42 | 33.4 | From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels. | W A Catterall | Neuron | 2000 | 10798388 | No |
1857 | 1564 | 1564.0 | 47.95 | 48.0 | Ordinary magic. Resilience processes in development. | A S Masten | Am Psychol | 2001 | 11315249 | Yes |
1858 | 3128 | 1564.0 | 67.15 | 33.6 | Complex networks orchestrate epithelial-mesenchymal transitions. | Jean Paul Thiery, Jonathan P Sleeman | Nat Rev Mol Cell Biol | 2006 | 16493418 | No |
1859 | 1564 | 1564.0 | 0.0 | 0.0 | The estimation of phosphorus. | R J Allen | Biochem J | 1940 | 16747230 | Yes |
1860 | 1563 | 1563.0 | 28.53 | 28.5 | Selforganization of matter and the evolution of biological macromolecules. | M Eigen | Naturwissenschaften | 1971 | 4942363 | No |
1861 | 1563 | 1563.0 | 37.31 | 37.3 | The biology of incretin hormones. | Daniel J Drucker | Cell Metab | 2006 | 16517403 | No |
1862 | 1562 | 1562.0 | 35.77 | 35.8 | Neurotrophin-regulated signalling pathways. | Louis F Reichardt | Philos Trans R Soc Lond B Biol Sci | 2006 | 16939974 | No |
1863 | 1561 | 1561.0 | 52.29 | 52.3 | Screening for prostate cancer: U.S. Preventive Services Task Force recommendation statement. | Virginia A Moyer | Ann Intern Med | 2012 | 22801674 | No |
1864 | 1561 | 1561.0 | 52.21 | 52.2 | The role of senescent cells in ageing. | Jan M van Deursen | Nature | 2014 | 24848057 | No |
1865 | 3121 | 1560.5 | 65.53 | 32.8 | Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome. | C B Lozzio, B B Lozzio | Blood | 1975 | 163658 | Yes |
1866 | 1560 | 1560.0 | 29.69 | 29.7 | Protein degradation and protection against misfolded or damaged proteins. | Alfred L Goldberg | Nature | 2003 | 14685250 | No |
1867 | 3120 | 1560.0 | 74.38 | 37.2 | Unravelling the pathogenesis of inflammatory bowel disease. | R J Xavier, D K Podolsky | Nature | 2007 | 17653185 | No |
1868 | 4680 | 1560.0 | 120.97 | 40.3 | Optimization by simulated annealing. | S Kirkpatrick, C D Gelatt, M P Vecchi | Science | 1983 | 17813860 | Yes |
1869 | 3120 | 1560.0 | 133.83 | 66.9 | Parkinson's disease. | Lorraine V Kalia, Anthony E Lang | Lancet | 2015 | 25904081 | No |
1870 | 1560 | 1560.0 | 58.7 | 58.7 | Modeling Development and Disease with Organoids. | Hans Clevers | Cell | 2016 | 27315476 | No |
1871 | 3119 | 1559.5 | 101.04 | 50.5 | The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today. | R Doll, R Peto | J Natl Cancer Inst | 1981 | 7017215 | No |
1872 | 4678 | 1559.3 | 87.25 | 29.1 | Notch signaling: cell fate control and signal integration in development. | S Artavanis-Tsakonas, M D Rand, R J Lake | Science | 1999 | 10221902 | No |
1873 | 1559 | 1559.0 | 41.32 | 41.3 | A more meaningful scoring system for determining the severity of coronary heart disease. | G G Gensini | Am J Cardiol | 1983 | 6823874 | Yes |
1874 | 3118 | 1559.0 | 66.96 | 33.5 | Cancer metastasis: building a framework. | Gaorav P Gupta, Joan Massagué | Cell | 2006 | 17110329 | No |
1875 | 3115 | 1557.5 | 69.95 | 35.0 | The human plasma proteome: history, character, and diagnostic prospects. | N Leigh Anderson, Norman G Anderson | Mol Cell Proteomics | 2002 | 12488461 | No |
1876 | 1557 | 1557.0 | 31.41 | 31.4 | The ubiquitin-proteasome proteolytic pathway. | A Ciechanover | Cell | 1994 | 7923371 | No |
1877 | 1557 | 1557.0 | 25.86 | 25.9 | Neuronal specification in the spinal cord: inductive signals and transcriptional codes. | T M Jessell | Nat Rev Genet | 2000 | 11262869 | No |
1878 | 1557 | 1557.0 | 46.18 | 46.2 | A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. | Ozcan Erel | Clin Biochem | 2004 | 15003729 | Yes |
1879 | 1556 | 1556.0 | 77.49 | 77.5 | Bias in analytic research. | D L Sackett | J Chronic Dis | 1979 | 447779 | Yes |
1880 | 1556 | 1556.0 | 77.61 | 77.6 | Muscle and tendon: properties, models, scaling, and application to biomechanics and motor control. | F E Zajac | Crit Rev Biomed Eng | 1989 | 2676342 | No |
1881 | 6223 | 1555.8 | 153.8 | 38.5 | Most mammalian mRNAs are conserved targets of microRNAs. | Robin C Friedman, Kyle Kai-How Farh, Christopher B Burge, David P Bartel | Genome Res | 2009 | 18955434 | Yes |
1882 | 4665 | 1555.0 | 92.36 | 30.8 | Efficient selection for high-expression transfectants with a novel eukaryotic vector. | H Niwa, K Yamamura, J Miyazaki | Gene | 1991 | 1660837 | Yes |
1883 | 3110 | 1555.0 | 100.33 | 50.2 | Neoantigens in cancer immunotherapy. | Ton N Schumacher, Robert D Schreiber | Science | 2015 | 25838375 | No |
1884 | 4664 | 1554.7 | 103.76 | 34.6 | Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer. | M A Frohman, M K Dush, G R Martin | Proc Natl Acad Sci U S A | 1988 | 2461560 | Yes |
1885 | 3107 | 1553.5 | 58.41 | 29.2 | Mutations affecting segment number and polarity in Drosophila. | C Nüsslein-Volhard, E Wieschaus | Nature | 1980 | 6776413 | Yes |
1886 | 3104 | 1552.0 | 43.4 | 21.7 | Computed circular dichroism spectra for the evaluation of protein conformation. | N Greenfield, G D Fasman | Biochemistry | 1969 | 5346390 | Yes |
1887 | 1552 | 1552.0 | 54.17 | 54.2 | Multimodal approach to control postoperative pathophysiology and rehabilitation. | H Kehlet | Br J Anaesth | 1997 | 9175983 | No |
1888 | 1552 | 1552.0 | 73.62 | 73.6 | Computing Inter-Rater Reliability for Observational Data: An Overview and Tutorial. | Kevin A Hallgren | Tutor Quant Methods Psychol | 2012 | 22833776 | Yes |
1889 | 3103 | 1551.5 | 79.39 | 39.7 | Dali server: conservation mapping in 3D. | Liisa Holm, Päivi Rosenström | Nucleic Acids Res | 2010 | 20457744 | Yes |
1890 | 3103 | 1551.5 | 102.95 | 51.5 | The future of immune checkpoint therapy. | Padmanee Sharma, James P Allison | Science | 2015 | 25838373 | No |
1891 | 1551 | 1551.0 | 0.0 | 0.0 | Cerebral vascular accidents in patients over the age of 60. II. Prognosis. | J Rankin | Scott Med J | 1957 | 13432835 | Yes |
1892 | 1550 | 1550.0 | 32.45 | 32.5 | Drug discovery: a historical perspective. | J Drews | Science | 2000 | 10720314 | No |
1893 | 3100 | 1550.0 | 122.93 | 61.5 | Alginate: properties and biomedical applications. | Kuen Yong Lee, David J Mooney | Prog Polym Sci | 2012 | 22125349 | Yes |
1894 | 4648 | 1549.3 | 88.46 | 29.5 | A highly sensitive adenylate cyclase assay. | Y Salomon, C Londos, M Rodbell | Anal Biochem | 1974 | 4827395 | Yes |
1895 | 1549 | 1549.0 | 36.67 | 36.7 | The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. | H Maeda | Adv Enzyme Regul | 2001 | 11384745 | No |
1896 | 1549 | 1549.0 | 33.26 | 33.3 | Tumor metastasis: mechanistic insights and clinical challenges. | Patricia S Steeg | Nat Med | 2006 | 16892035 | No |
1897 | 3098 | 1549.0 | 73.76 | 36.9 | Malignant gliomas in adults. | Patrick Y Wen, Santosh Kesari | N Engl J Med | 2008 | 18669428 | No |
1898 | 1549 | 1549.0 | 65.7 | 65.7 | Macrophage Polarization. | Peter J Murray | Annu Rev Physiol | 2017 | 27813830 | No |
1899 | 15480 | 1548.0 | 368.97 | 36.9 | Multilineage potential of adult human mesenchymal stem cells. | M F Pittenger, A M Mackay, S C Beck, R K Jaiswal, R Douglas, J D Mosca, M A Moorman, D W Simonetti, S Craig, D R Marshak | Science | 1999 | 10102814 | Yes |
1900 | 3095 | 1547.5 | 62.03 | 31.0 | Toll-like receptor control of the adaptive immune responses. | Akiko Iwasaki, Ruslan Medzhitov | Nat Immunol | 2004 | 15454922 | No |
1901 | 4639 | 1546.3 | 155.35 | 51.8 | Phylogenetic identification and in situ detection of individual microbial cells without cultivation. | R I Amann, W Ludwig, K H Schleifer | Microbiol Rev | 1995 | 7535888 | No |
1902 | 3092 | 1546.0 | 74.85 | 37.4 | Steatohepatitis: a tale of two "hits"? | C P Day, O F James | Gastroenterology | 1998 | 9547102 | No |
1903 | 1545 | 1545.0 | 42.4 | 42.4 | Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum. | A Fabiato | Am J Physiol | 1983 | 6346892 | No |
1904 | 3090 | 1545.0 | 75.0 | 37.5 | Cell signaling by receptor tyrosine kinases. | Mark A Lemmon, Joseph Schlessinger | Cell | 2010 | 20602996 | No |
1905 | 1544 | 1544.0 | 43.89 | 43.9 | Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy. | A E Pegg | Cancer Res | 1988 | 3123052 | No |
1906 | 1543 | 1543.0 | 47.06 | 47.1 | Domino Reactions in Organic Synthesis. | Lutz F. Tietze | Chem Rev | 1996 | 11848746 | Yes |
1907 | 3086 | 1543.0 | 66.15 | 33.1 | Self-assembly at all scales. | George M Whitesides, Bartosz Grzybowski | Science | 2002 | 11923529 | Yes |
1908 | 1542 | 1542.0 | 30.37 | 30.4 | E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. | J R Nevins | Science | 1992 | 1411535 | Yes |
1909 | 3082 | 1541.0 | 71.8 | 35.9 | New Giemsa method for the differential staining of sister chromatids. | P Perry, S Wolff | Nature | 1974 | 4138930 | Yes |
1910 | 1540 | 1540.0 | 56.13 | 56.1 | Statistical analysis of enzyme kinetic data. | W W Cleland | Methods Enzymol | 1979 | 502857 | Yes |
1911 | 1540 | 1540.0 | 34.89 | 34.9 | Pathogenesis of group A streptococcal infections. | M W Cunningham | Clin Microbiol Rev | 2000 | 10885988 | No |
1912 | 1540 | 1540.0 | 30.94 | 30.9 | RNA silencing in plants. | David Baulcombe | Nature | 2004 | 15372043 | No |
1913 | 1539 | 1539.0 | 60.97 | 61.0 | A structured interview guide for the Hamilton Depression Rating Scale. | J B Williams | Arch Gen Psychiatry | 1988 | 3395203 | Yes |
1914 | 1539 | 1539.0 | 37.23 | 37.2 | Clinical features of metastatic bone disease and risk of skeletal morbidity. | Robert E Coleman | Clin Cancer Res | 2006 | 17062708 | No |
1915 | 1539 | 1539.0 | 38.11 | 38.1 | Use and misuse of the receiver operating characteristic curve in risk prediction. | Nancy R Cook | Circulation | 2007 | 17309939 | Yes |
1916 | 1538 | 1538.0 | 52.92 | 52.9 | Biological applications of ionophores. | B C Pressman | Annu Rev Biochem | 1976 | 786156 | No |
1917 | 1538 | 1538.0 | 34.02 | 34.0 | Molecular themes in oncogenesis. | J M Bishop | Cell | 1991 | 1988146 | No |
1918 | 1538 | 1538.0 | 48.24 | 48.2 | The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate. | G R Buettner | Arch Biochem Biophys | 1993 | 8434935 | No |
1919 | 3075 | 1537.5 | 105.56 | 52.8 | Diabetes and cardiovascular disease. The Framingham study. | W B Kannel, D L McGee | JAMA | 1979 | 430798 | Yes |
1920 | 3075 | 1537.5 | 114.49 | 57.2 | Universal chemical assay for the detection and determination of siderophores. | B Schwyn, J B Neilands | Anal Biochem | 1987 | 2952030 | Yes |
1921 | 4612 | 1537.3 | 97.45 | 32.5 | Adjusting batch effects in microarray expression data using empirical Bayes methods. | W Evan Johnson, Cheng Li, Ariel Rabinovic | Biostatistics | 2007 | 16632515 | Yes |
1922 | 9223 | 1537.2 | 218.06 | 36.3 | GROMACS: fast, flexible, and free. | David Van Der Spoel, Erik Lindahl, Berk Hess, Gerrit Groenhof, Alan E Mark, Herman J C Berendsen | J Comput Chem | 2005 | 16211538 | Yes |
1923 | 1537 | 1537.0 | 42.64 | 42.6 | Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy. | Y Ben-Ari | Neuroscience | 1985 | 2859548 | No |
1924 | 1537 | 1537.0 | 47.85 | 47.9 | Evidence for a central component of post-injury pain hypersensitivity. | C J Woolf | Nature | 1983 | 6656869 | Yes |
1925 | 3074 | 1537.0 | 78.97 | 39.5 | Empirical threshold values for quantitative trait mapping. | G A Churchill, R W Doerge | Genetics | 1994 | 7851788 | Yes |
1926 | 1537 | 1537.0 | 0.0 | 0.0 | Nutrition needs of mammalian cells in tissue culture. | H Eagle | Science | 1955 | 13255879 | Yes |
1927 | 3073 | 1536.5 | 0.0 | 0.0 | A method for the determination of desoxyribonucleic acid, ribonucleic acid, and phosphoproteins in animal tissues. | G Schmidt, S J Thannhauser | J Biol Chem | 1945 | 21005717 | Yes |
1928 | 1536 | 1536.0 | 43.46 | 43.5 | Glycobiology: Toward Understanding the Function of Sugars. | Raymond A. Dwek | Chem Rev | 1996 | 11848770 | Yes |
1929 | 1536 | 1536.0 | 30.7 | 30.7 | The Buccaneer software for automated model building. 1. Tracing protein chains. | Kevin Cowtan | Acta Crystallogr D Biol Crystallogr | 2006 | 16929101 | Yes |
1930 | 3071 | 1535.5 | 15.52 | 7.8 | Junctional complexes in various epithelia. | M G Farquhar, G E Palade | J Cell Biol | 1963 | 13944428 | Yes |
1931 | 1535 | 1535.0 | 45.82 | 45.8 | Calcium release from the sarcoplasmic reticulum. | M Endo | Physiol Rev | 1977 | 13441 | Yes |
1932 | 1535 | 1535.0 | 31.29 | 31.3 | Antigen-Antibody Crossed Electrophoresis. | C B Laurell | Anal Biochem | 1965 | 14302464 | Yes |
1933 | 1535 | 1535.0 | 41.97 | 42.0 | n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases. | Philip C Calder | Am J Clin Nutr | 2006 | 16841861 | No |
1934 | 1534 | 1534.0 | 24.04 | 24.0 | An enzymic method for the trace iodination of immunoglobulins and other proteins. | J J Marchalonis | Biochem J | 1969 | 4185494 | Yes |
1935 | 1534 | 1534.0 | 36.85 | 36.9 | Myeloperoxidase: friend and foe. | Seymour J Klebanoff | J Leukoc Biol | 2005 | 15689384 | No |
1936 | 1534 | 1534.0 | 58.06 | 58.1 | A Protection Motivation Theory of Fear Appeals and Attitude Change1. | Ronald W Rogers | J Psychol | 1975 | 28136248 | Yes |
1937 | 3067 | 1533.5 | 67.65 | 33.8 | Cell migration: a physically integrated molecular process. | D A Lauffenburger, A F Horwitz | Cell | 1996 | 8608589 | No |
1938 | 6132 | 1533.0 | 208.91 | 52.2 | Guidelines for the process of cross-cultural adaptation of self-report measures. | D E Beaton, C Bombardier, F Guillemin, M B Ferraz | Spine (Phila Pa 1976) | 2000 | 11124735 | No |
1939 | 1532 | 1532.0 | 38.72 | 38.7 | Early signals in the mitogenic response. | E Rozengurt | Science | 1986 | 3018928 | No |
1940 | 3064 | 1532.0 | 61.8 | 30.9 | The Bcl2 family: regulators of the cellular life-or-death switch. | Suzanne Cory, Jerry M Adams | Nat Rev Cancer | 2002 | 12209154 | No |
1941 | 6128 | 1532.0 | 120.03 | 30.0 | A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. | B M Bolstad, R A Irizarry, M Astrand, T P Speed | Bioinformatics | 2003 | 12538238 | Yes |
1942 | 1532 | 1532.0 | 34.55 | 34.5 | The Unified Medical Language System (UMLS): integrating biomedical terminology. | Olivier Bodenreider | Nucleic Acids Res | 2004 | 14681409 | Yes |
1943 | 3062 | 1531.0 | 70.82 | 35.4 | A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. | L Buck, R Axel | Cell | 1991 | 1840504 | Yes |
1944 | 1531 | 1531.0 | 45.37 | 45.4 | Recent advances in the biochemistry of polyamines in eukaryotes. | A E Pegg | Biochem J | 1986 | 3087344 | No |
1945 | 1531 | 1531.0 | 47.56 | 47.6 | Some observations upon a new inhibitor of monoamine oxidase in brain tissue. | J P Johnston | Biochem Pharmacol | 1968 | 5659776 | Yes |
1946 | 3062 | 1531.0 | 62.62 | 31.3 | Development by self-digestion: molecular mechanisms and biological functions of autophagy. | Beth Levine, Daniel J Klionsky | Dev Cell | 2004 | 15068787 | No |
1947 | 1531 | 1531.0 | 61.35 | 61.4 | α-band oscillations, attention, and controlled access to stored information. | Wolfgang Klimesch | Trends Cogn Sci | 2012 | 23141428 | No |
1948 | 3062 | 1531.0 | 95.21 | 47.6 | How good are my data and what is the resolution? | Philip R Evans, Garib N Murshudov | Acta Crystallogr D Biol Crystallogr | 2013 | 23793146 | Yes |
1949 | 7652 | 1530.4 | 152.17 | 30.4 | Prospective identification of tumorigenic breast cancer cells. | Muhammad Al-Hajj, Max S Wicha, Adalberto Benito-Hernandez, Sean J Morrison, Michael F Clarke | Proc Natl Acad Sci U S A | 2003 | 12629218 | Yes |
1950 | 3060 | 1530.0 | 56.45 | 28.2 | Cellular motility driven by assembly and disassembly of actin filaments. | Thomas D Pollard, Gary G Borisy | Cell | 2003 | 12600310 | No |
1951 | 1530 | 1530.0 | 35.83 | 35.8 | Upconversion and anti-Stokes processes with f and d ions in solids. | François Auzel | Chem Rev | 2004 | 14719973 | Yes |
1952 | 1530 | 1530.0 | 43.37 | 43.4 | Surface plasmon resonance sensors for detection of chemical and biological species. | Jirí Homola | Chem Rev | 2008 | 18229953 | No |
1953 | 1528 | 1528.0 | 28.45 | 28.4 | Vienna RNA secondary structure server. | Ivo L Hofacker | Nucleic Acids Res | 2003 | 12824340 | Yes |
1954 | 3054 | 1527.0 | 91.6 | 45.8 | Quality control and preprocessing of metagenomic datasets. | Robert Schmieder, Robert Edwards | Bioinformatics | 2011 | 21278185 | Yes |
1955 | 1527 | 1527.0 | 63.21 | 63.2 | Nonalcoholic fatty liver disease: a systematic review. | Mary E Rinella | JAMA | 2015 | 26057287 | No |
1956 | 3053 | 1526.5 | 180.73 | 90.4 | A scaled version of the General Health Questionnaire. | D P Goldberg, V F Hillier | Psychol Med | 1979 | 424481 | Yes |
1957 | 1526 | 1526.0 | 41.27 | 41.3 | Stress and depression. | Constance Hammen | Annu Rev Clin Psychol | 2005 | 17716090 | No |
1958 | 1525 | 1525.0 | 41.34 | 41.3 | Tumor invasion and metastases--role of the extracellular matrix: Rhoads Memorial Award lecture. | L A Liotta | Cancer Res | 1986 | 2998604 | No |
1959 | 3047 | 1523.5 | 62.94 | 31.5 | Coordination of circadian timing in mammals. | Steven M Reppert, David R Weaver | Nature | 2002 | 12198538 | No |
1960 | 1523 | 1523.0 | 38.08 | 38.1 | Trophic factors and neuronal survival. | Y A Barde | Neuron | 1989 | 2697237 | No |
1961 | 1522 | 1522.0 | 37.96 | 38.0 | Type I diabetes mellitus. A chronic autoimmune disease. | G S Eisenbarth | N Engl J Med | 1986 | 3517648 | No |
1962 | 1522 | 1522.0 | 29.85 | 29.9 | Macromolecular crowding: obvious but underappreciated. | R J Ellis | Trends Biochem Sci | 2001 | 11590012 | No |
1963 | 1522 | 1522.0 | 34.53 | 34.5 | Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study). | K M Fox | Lancet | 2003 | 13678872 | Yes |
1964 | 3044 | 1522.0 | 75.98 | 38.0 | Obesity. | David W Haslam, W Philip T James | Lancet | 2005 | 16198769 | No |
1965 | 4565 | 1521.7 | 96.8 | 32.3 | The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. | S K Hanks, A M Quinn, T Hunter | Science | 1988 | 3291115 | No |
1966 | 1521 | 1521.0 | 50.43 | 50.4 | Deliberate practice and the acquisition and maintenance of expert performance in medicine and related domains. | K Anders Ericsson | Acad Med | 2004 | 15383395 | No |
1967 | 1521 | 1521.0 | 41.93 | 41.9 | Bioactive microbial metabolites. | János Bérdy | J Antibiot (Tokyo) | 2005 | 15813176 | No |
1968 | 1520 | 1520.0 | 18.6 | 18.6 | A soluble protein characteristic of the nervous system. | B W Moore | Biochem Biophys Res Commun | 1965 | 4953930 | Yes |
1969 | 4558 | 1519.3 | 102.98 | 34.3 | Click Chemistry: Diverse Chemical Function from a Few Good Reactions. | Hartmuth C. Kolb, M G Finn, K. Barry Sharpless | Angew Chem Int Ed Engl | 2001 | 11433435 | Yes |
1970 | 3038 | 1519.0 | 71.23 | 35.6 | Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. | F Q Schafer, G R Buettner | Free Radic Biol Med | 2001 | 11368918 | No |
1971 | 1519 | 1519.0 | 33.66 | 33.7 | Ordered porous materials for emerging applications. | Mark E Davis | Nature | 2002 | 12075343 | No |
1972 | 1518 | 1518.0 | 48.02 | 48.0 | Stability of proteins: small globular proteins. | P L Privalov | Adv Protein Chem | 1979 | 44431 | No |
1973 | 3035 | 1517.5 | 140.99 | 70.5 | MicroRNA therapeutics: towards a new era for the management of cancer and other diseases. | Rajesha Rupaimoole, Frank J Slack | Nat Rev Drug Discov | 2017 | 28209991 | No |
1974 | 1517 | 1517.0 | 47.22 | 47.2 | The law of attrition. | Gunther Eysenbach | J Med Internet Res | 2005 | 15829473 | Yes |
1975 | 1516 | 1516.0 | 34.43 | 34.4 | Dopamine (3-hydroxytyramine) and brain function. | O Hornykiewicz | Pharmacol Rev | 1966 | 5328389 | No |
1976 | 3031 | 1515.5 | 67.37 | 33.7 | NF-kappaB: a key role in inflammatory diseases. | P P Tak, G S Firestein | J Clin Invest | 2001 | 11134171 | No |
1977 | 9092 | 1515.3 | 260.39 | 43.4 | A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. | Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier | Science | 2012 | 22745249 | Yes |
1978 | 4543 | 1514.3 | 98.48 | 32.8 | Osteoclast differentiation and activation. | William J Boyle, W Scott Simonet, David L Lacey | Nature | 2003 | 12748652 | No |
1979 | 3027 | 1513.5 | 101.54 | 50.8 | Thermodynamics of protein association reactions: forces contributing to stability. | P D Ross, S Subramanian | Biochemistry | 1981 | 7248271 | Yes |
1980 | 1513 | 1513.0 | 40.0 | 40.0 | Reversible binding of Pi by beef heart mitochondrial adenosine triphosphatase. | H S Penefsky | J Biol Chem | 1977 | 16006 | Yes |
1981 | 1513 | 1513.0 | 47.97 | 48.0 | Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. | C A Barnes | J Comp Physiol Psychol | 1979 | 221551 | Yes |
1982 | 4538 | 1512.7 | 115.77 | 38.6 | Cortical surface-based analysis. II: Inflation, flattening, and a surface-based coordinate system. | B Fischl, M I Sereno, A M Dale | Neuroimage | 1999 | 9931269 | Yes |
1983 | 1512 | 1512.0 | 50.56 | 50.6 | A Social Neuroscience Perspective on Adolescent Risk-Taking. | Laurence Steinberg | Dev Rev | 2008 | 18509515 | Yes |
1984 | 3024 | 1512.0 | 104.48 | 52.2 | Van der Waals heterostructures. | A K Geim, I V Grigorieva | Nature | 2013 | 23887427 | Yes |
1985 | 3023 | 1511.5 | 80.09 | 40.0 | The gut microbiota shapes intestinal immune responses during health and disease. | June L Round, Sarkis K Mazmanian | Nat Rev Immunol | 2009 | 19343057 | No |
1986 | 1511 | 1511.0 | 55.73 | 55.7 | Atherogenesis: a postprandial phenomenon. | D B Zilversmit | Circulation | 1979 | 222498 | Yes |
1987 | 1511 | 1511.0 | 89.45 | 89.5 | Stimulated acoustic emissions from within the human auditory system. | D T Kemp | J Acoust Soc Am | 1978 | 744838 | Yes |
1988 | 1511 | 1511.0 | 28.03 | 28.0 | Aggresomes, inclusion bodies and protein aggregation. | R R Kopito | Trends Cell Biol | 2000 | 11121744 | No |
1989 | 1511 | 1511.0 | 32.76 | 32.8 | The tumor microenvironment and its role in promoting tumor growth. | T L Whiteside | Oncogene | 2008 | 18836471 | No |
1990 | 1510 | 1510.0 | 33.09 | 33.1 | Far-field optical nanoscopy. | Stefan W Hell | Science | 2007 | 17525330 | No |
1991 | 3019 | 1509.5 | 108.09 | 54.0 | The M1 and M2 paradigm of macrophage activation: time for reassessment. | Fernando O Martinez, Siamon Gordon | F1000Prime Rep | 2014 | 24669294 | No |
1992 | 1509 | 1509.0 | 50.1 | 50.1 | Stereology of arbitrary particles. A review of unbiased number and size estimators and the presentation of some new ones, in memory of William R. Thompson. | H J Gundersen | J Microsc | 1986 | 3761363 | Yes |
1993 | 3017 | 1508.5 | 464.1 | 232.1 | Interactive Tree Of Life (iTOL) v5: an online tool for phylogenetic tree display and annotation. | Ivica Letunic, Peer Bork | Nucleic Acids Res | 2021 | 33885785 | Yes |
1994 | 1508 | 1508.0 | 45.14 | 45.1 | Signal transduction by reactive oxygen species. | Toren Finkel | J Cell Biol | 2011 | 21746850 | No |
1995 | 4523 | 1507.7 | 162.04 | 54.0 | Hydroperoxide metabolism in mammalian organs. | B Chance, H Sies, A Boveris | Physiol Rev | 1979 | 37532 | Yes |
1996 | 3012 | 1506.0 | 58.97 | 29.5 | Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. | P J Mitchell, R Tjian | Science | 1989 | 2667136 | No |
1997 | 3012 | 1506.0 | 89.15 | 44.6 | Extended-connectivity fingerprints. | David Rogers, Mathew Hahn | J Chem Inf Model | 2010 | 20426451 | Yes |
1998 | 3010 | 1505.0 | 86.26 | 43.1 | What's the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes. | J Zhang, K F Yu | JAMA | 1998 | 9832001 | Yes |
1999 | 1504 | 1504.0 | 47.97 | 48.0 | Health consequences of obesity in youth: childhood predictors of adult disease. | W H Dietz | Pediatrics | 1998 | 12224658 | No |
2000 | 3008 | 1504.0 | 79.52 | 39.8 | Materials for electrochemical capacitors. | Patrice Simon, Yury Gogotsi | Nat Mater | 2008 | 18956000 | Yes |
2001 | 3008 | 1504.0 | 67.79 | 33.9 | The DNA damage response: making it safe to play with knives. | Alberto Ciccia, Stephen J Elledge | Mol Cell | 2010 | 20965415 | No |
2002 | 3006 | 1503.0 | 86.76 | 43.4 | Accessories to the crime: functions of cells recruited to the tumor microenvironment. | Douglas Hanahan, Lisa M Coussens | Cancer Cell | 2012 | 22439926 | No |
2003 | 3005 | 1502.5 | 57.43 | 28.7 | Missing pieces in the NF-kappaB puzzle. | Sankar Ghosh, Michael Karin | Cell | 2002 | 11983155 | No |
2004 | 4507 | 1502.3 | 127.2 | 42.4 | The fusiform face area: a module in human extrastriate cortex specialized for face perception. | N Kanwisher, J McDermott, M M Chun | J Neurosci | 1997 | 9151747 | Yes |
2005 | 1502 | 1502.0 | 51.56 | 51.6 | Lyme disease. | A C Steere | N Engl J Med | 1989 | 2668764 | No |
2006 | 3004 | 1502.0 | 176.9 | 88.5 | Rating systems in the evaluation of knee ligament injuries. | Y Tegner, J Lysholm | Clin Orthop Relat Res | 1985 | 4028566 | Yes |
2007 | 1502 | 1502.0 | 33.61 | 33.6 | The molecular logic of endocannabinoid signalling. | Daniele Piomelli | Nat Rev Neurosci | 2003 | 14595399 | No |
2008 | 3004 | 1502.0 | 78.8 | 39.4 | Lipid rafts as a membrane-organizing principle. | Daniel Lingwood, Kai Simons | Science | 2010 | 20044567 | No |
2009 | 1501 | 1501.0 | 34.16 | 34.2 | Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors. | J C Unkeless | J Exp Med | 1979 | 90108 | Yes |
2010 | 1501 | 1501.0 | 40.4 | 40.4 | Rheumatoid arthritis. Pathophysiology and implications for therapy. | E D Harris | N Engl J Med | 1990 | 2271017 | No |
2011 | 9005 | 1500.8 | 283.15 | 47.2 | TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. | Daehwan Kim, Geo Pertea, Cole Trapnell, Harold Pimentel, Ryan Kelley, Steven L Salzberg | Genome Biol | 2013 | 23618408 | Yes |
2012 | 1500 | 1500.0 | 31.57 | 31.6 | Cancer epigenomics: DNA methylomes and histone-modification maps. | Manel Esteller | Nat Rev Genet | 2007 | 17339880 | No |
2013 | 1500 | 1500.0 | 58.8 | 58.8 | Screening for lung cancer: U.S. Preventive Services Task Force recommendation statement. | Virginia A Moyer | Ann Intern Med | 2014 | 24378917 | No |
2014 | 2999 | 1499.5 | 89.76 | 44.9 | Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI. | P J Basser, C Pierpaoli | J Magn Reson B | 1996 | 8661285 | Yes |
2015 | 1497 | 1497.0 | 42.71 | 42.7 | Isolated removal of hypothalamic or other brain nuclei of the rat. | M Palkovits | Brain Res | 1973 | 4747772 | Yes |
2016 | 1497 | 1497.0 | 33.67 | 33.7 | Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone. | M B Luskin | Neuron | 1993 | 8338665 | Yes |
2017 | 2994 | 1497.0 | 0.0 | 0.0 | Lactic dehydrogenase activity in blood. | F Wroblewski, J S Ladue | Proc Soc Exp Biol Med | 1955 | 13273400 | Yes |
2018 | 1496 | 1496.0 | 32.92 | 32.9 | Hyaluronan: from extracellular glue to pericellular cue. | Bryan P Toole | Nat Rev Cancer | 2004 | 15229478 | No |
2019 | 1496 | 1496.0 | 0.0 | 0.0 | The colorimetric determination of phosphorus. | E J King | Biochem J | 1932 | 16744823 | Yes |
2020 | 1494 | 1494.0 | 39.05 | 39.0 | The human immunodeficiency virus: infectivity and mechanisms of pathogenesis. | A S Fauci | Science | 1988 | 3277274 | No |
2021 | 1494 | 1494.0 | 37.12 | 37.1 | Reconciling the chemistry and biology of reactive oxygen species. | Christine C Winterbourn | Nat Chem Biol | 2008 | 18421291 | No |
2022 | 2987 | 1493.5 | 0.0 | 0.0 | Mutations of Bacteria from Virus Sensitivity to Virus Resistance. | S E Luria, M Delbrück | Genetics | 1943 | 17247100 | Yes |
2023 | 1493 | 1493.0 | 33.15 | 33.1 | Tumor suppressor genes. | R A Weinberg | Science | 1991 | 1659741 | No |
2024 | 2986 | 1493.0 | 60.26 | 30.1 | Chemokines: a new classification system and their role in immunity. | A Zlotnik, O Yoshie | Immunity | 2000 | 10714678 | No |
2025 | 2983 | 1491.5 | 88.24 | 44.1 | Porosity of 3D biomaterial scaffolds and osteogenesis. | Vassilis Karageorgiou, David Kaplan | Biomaterials | 2005 | 15860204 | No |
2026 | 1491 | 1491.0 | 29.73 | 29.7 | Coupling of enzymes to proteins with glutaraldehyde. Use of the conjugates for the detection of antigens and antibodies. | S Avrameas | Immunochemistry | 1969 | 4975324 | Yes |
2027 | 1490 | 1490.0 | 33.17 | 33.2 | Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis. | C Taswell | J Immunol | 1981 | 7009746 | Yes |
2028 | 2980 | 1490.0 | 66.35 | 33.2 | How matrix metalloproteinases regulate cell behavior. | M D Sternlicht, Z Werb | Annu Rev Cell Dev Biol | 2001 | 11687497 | No |
2029 | 1489 | 1489.0 | 39.82 | 39.8 | Redox signaling: nitrosylation and related target interactions of nitric oxide. | J S Stamler | Cell | 1994 | 7923362 | No |
2030 | 4466 | 1488.7 | 120.46 | 40.2 | I-TASSER: a unified platform for automated protein structure and function prediction. | Ambrish Roy, Alper Kucukural, Yang Zhang | Nat Protoc | 2010 | 20360767 | Yes |
2031 | 1488 | 1488.0 | 49.59 | 49.6 | The measurement of psychological androgyny. | S L Bem | J Consult Clin Psychol | 1974 | 4823550 | Yes |
2032 | 1488 | 1488.0 | 26.03 | 26.0 | Histone acetylation and transcriptional regulatory mechanisms. | K Struhl | Genes Dev | 1998 | 9499396 | No |
2033 | 1487 | 1487.0 | 21.51 | 21.5 | Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate. | J W Olney | Science | 1969 | 5778021 | Yes |
2034 | 1487 | 1487.0 | 46.21 | 46.2 | Polycystic ovary syndrome. | S Franks | N Engl J Med | 1995 | 7651477 | No |
2035 | 1487 | 1487.0 | 36.92 | 36.9 | An economic method for the fluorescent labeling of PCR fragments. | M Schuelke | Nat Biotechnol | 2000 | 10657137 | Yes |
2036 | 1487 | 1487.0 | 48.56 | 48.6 | The World Oral Health Report 2003: continuous improvement of oral health in the 21st century--the approach of the WHO Global Oral Health Programme. | Poul Erik Petersen | Community Dent Oral Epidemiol | 2003 | 15015736 | Yes |
2037 | 1487 | 1487.0 | 32.03 | 32.0 | Critical period plasticity in local cortical circuits. | Takao K Hensch | Nat Rev Neurosci | 2005 | 16261181 | No |
2038 | 1487 | 1487.0 | 58.33 | 58.3 | MorphoJ: an integrated software package for geometric morphometrics. | Christian Peter Klingenberg | Mol Ecol Resour | 2011 | 21429143 | Yes |
2039 | 2973 | 1486.5 | 64.68 | 32.3 | Cellular senescence: when bad things happen to good cells. | Judith Campisi, Fabrizio d'Adda di Fagagna | Nat Rev Mol Cell Biol | 2007 | 17667954 | No |
2040 | 1485 | 1485.0 | 19.97 | 20.0 | The mechanism of muscular contraction. | H E Huxley | Science | 1969 | 4181952 | No |
2041 | 4455 | 1485.0 | 115.11 | 38.4 | How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. | R M Sapolsky, L M Romero, A U Munck | Endocr Rev | 2000 | 10696570 | No |
2042 | 1485 | 1485.0 | 41.16 | 41.2 | Emotion regulation: affective, cognitive, and social consequences. | James J Gross | Psychophysiology | 2002 | 12212647 | No |
2043 | 2970 | 1485.0 | 82.38 | 41.2 | Genome regulation by long noncoding RNAs. | John L Rinn, Howard Y Chang | Annu Rev Biochem | 2012 | 22663078 | No |
2044 | 19299 | 1484.5 | 502.28 | 38.6 | Clustal W and Clustal X version 2.0. | M A Larkin, G Blackshields, N P Brown, R Chenna, P A McGettigan, H McWilliam, F Valentin, I M Wallace, A Wilm, R Lopez, J D Thompson, T J Gibson, D G Higgins | Bioinformatics | 2007 | 17846036 | Yes |
2045 | 1484 | 1484.0 | 42.97 | 43.0 | Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. | M D Maines | FASEB J | 1988 | 3290025 | No |
2046 | 8903 | 1483.8 | 209.38 | 34.9 | Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. | Hadi Valadi, Karin Ekström, Apostolos Bossios, Margareta Sjöstrand, James J Lee, Jan O Lötvall | Nat Cell Biol | 2007 | 17486113 | Yes |
2047 | 2967 | 1483.5 | 116.37 | 58.2 | Assessment of eating disorders: interview or self-report questionnaire? | C G Fairburn, S J Beglin | Int J Eat Disord | 1994 | 7866415 | Yes |
2048 | 1483 | 1483.0 | 45.74 | 45.7 | Superoxide dismutases. | I Fridovich | Annu Rev Biochem | 1975 | 1094908 | No |
2049 | 1483 | 1483.0 | 26.23 | 26.2 | R factor transfer in Rhizobium leguminosarum. | J E Beringer | J Gen Microbiol | 1974 | 4612098 | Yes |
2050 | 1483 | 1483.0 | 47.79 | 47.8 | SPSS and SAS programs for determining the number of components using parallel analysis and velicer's MAP test. | B P O'Connor | Behav Res Methods Instrum Comput | 2000 | 11029811 | Yes |
2051 | 10378 | 1482.6 | 221.69 | 31.7 | Embryonic stem cell lines derived from human blastocysts. | J A Thomson, J Itskovitz-Eldor, S S Shapiro, M A Waknitz, J J Swiergiel, V S Marshall, J M Jones | Science | 1998 | 9804556 | Yes |
2052 | 1482 | 1482.0 | 32.94 | 32.9 | Defective repair replication of DNA in xeroderma pigmentosum. | J E Cleaver | Nature | 1968 | 5655953 | Yes |
2053 | 1482 | 1482.0 | 40.45 | 40.5 | Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms. | J A Beavo | Physiol Rev | 1995 | 7480160 | No |
2054 | 2964 | 1482.0 | 99.45 | 49.7 | How useful is SBF in predicting in vivo bone bioactivity? | Tadashi Kokubo, Hiroaki Takadama | Biomaterials | 2006 | 16448693 | No |
2055 | 4446 | 1482.0 | 108.77 | 36.3 | Membrane lipids: where they are and how they behave. | Gerrit van Meer, Dennis R Voelker, Gerald W Feigenson | Nat Rev Mol Cell Biol | 2008 | 18216768 | No |
2056 | 1481 | 1481.0 | 35.21 | 35.2 | Neuronal synchrony: a versatile code for the definition of relations? | W Singer | Neuron | 1999 | 10677026 | No |
2057 | 2962 | 1481.0 | 63.98 | 32.0 | Escaping free-energy minima. | Alessandro Laio, Michele Parrinello | Proc Natl Acad Sci U S A | 2002 | 12271136 | Yes |
2058 | 1481 | 1481.0 | 5.69 | 5.7 | Chemoaffinity In The Orderly Growth Of Nerve Fiber Patterns And Connections. | R W Sperry | Proc Natl Acad Sci U S A | 1963 | 14077501 | Yes |
2059 | 2962 | 1481.0 | 76.87 | 38.4 | Improvement of phylogenies after removing divergent and ambiguously aligned blocks from protein sequence alignments. | Gerard Talavera, Jose Castresana | Syst Biol | 2007 | 17654362 | Yes |
2060 | 1480 | 1480.0 | 30.74 | 30.7 | Ionic blockage of sodium channels in nerve. | A M Woodhull | J Gen Physiol | 1973 | 4541078 | Yes |
2061 | 1480 | 1480.0 | 32.57 | 32.6 | The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes. | S E Kahn | Diabetologia | 2003 | 12637977 | No |
2062 | 2960 | 1480.0 | 91.13 | 45.6 | LigPlot+: multiple ligand-protein interaction diagrams for drug discovery. | Roman A Laskowski, Mark B Swindells | J Chem Inf Model | 2011 | 21919503 | Yes |
2063 | 1479 | 1479.0 | 33.85 | 33.9 | The cadherins: cell-cell adhesion molecules controlling animal morphogenesis. | M Takeichi | Development | 1988 | 3048970 | No |
2064 | 2958 | 1479.0 | 76.78 | 38.4 | The expanding universe of T-cell subsets: Th1, Th2 and more. | T R Mosmann, S Sad | Immunol Today | 1996 | 8820272 | No |
2065 | 1479 | 1479.0 | 42.92 | 42.9 | Mitochondria and cancer. | Douglas C Wallace | Nat Rev Cancer | 2012 | 23001348 | No |
2066 | 1478 | 1478.0 | 73.58 | 73.6 | Neutrophil extracellular traps in immunity and disease. | Venizelos Papayannopoulos | Nat Rev Immunol | 2018 | 28990587 | No |
2067 | 5909 | 1477.2 | 243.61 | 60.9 | A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. | M A Markwell, S M Haas, L L Bieber, N E Tolbert | Anal Biochem | 1978 | 98070 | Yes |
2068 | 1477 | 1477.0 | 65.26 | 65.3 | Human agency in social cognitive theory. | A Bandura | Am Psychol | 1989 | 2782727 | Yes |
2069 | 1477 | 1477.0 | 48.09 | 48.1 | Inflammation in atherosclerosis. | Peter Libby | Arterioscler Thromb Vasc Biol | 2012 | 22895665 | No |
2070 | 4430 | 1476.7 | 74.07 | 24.7 | Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs. | C A Winter, E A Risley, G W Nuss | Proc Soc Exp Biol Med | 1962 | 14001233 | Yes |
2071 | 1476 | 1476.0 | 39.92 | 39.9 | A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE Task Force on Classification and Terminology. | J Engel | Epilepsia | 2001 | 11422340 | Yes |
2072 | 4427 | 1475.7 | 32.58 | 10.9 | The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes. | J T Dodge, C Mitchell, D J Hanahan | Arch Biochem Biophys | 1963 | 14028302 | Yes |
2073 | 8853 | 1475.5 | 261.14 | 43.5 | Cancer statistics, 2009. | Ahmedin Jemal, Rebecca Siegel, Elizabeth Ward, Yongping Hao, Jiaquan Xu, Michael J Thun | CA Cancer J Clin | 2009 | 19474385 | Yes |
2074 | 1475 | 1475.0 | 64.57 | 64.6 | Derivation and validation of a short-form oral health impact profile. | G D Slade | Community Dent Oral Epidemiol | 1997 | 9332805 | Yes |
2075 | 1475 | 1475.0 | 24.9 | 24.9 | Evidence For The Existence Of Monoamine Neurons In The Central Nervous System. Iv. Distribution Of Monoamine Nerve Terminals In The Central Nervous System. | K Fuxe | Acta Physiol Scand Suppl | 1965 | 14319769 | Yes |
2076 | 4422 | 1474.0 | 153.98 | 51.3 | CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. | Teresa C Horan, Mary Andrus, Margaret A Dudeck | Am J Infect Control | 2008 | 18538699 | No |
2077 | 2946 | 1473.0 | 77.54 | 38.8 | A general method for isolation of high molecular weight DNA from eukaryotes. | N Blin, D W Stafford | Nucleic Acids Res | 1976 | 987581 | Yes |
2078 | 2946 | 1473.0 | 75.27 | 37.6 | Abdominal obesity and metabolic syndrome. | Jean-Pierre Després, Isabelle Lemieux | Nature | 2006 | 17167477 | No |
2079 | 1472 | 1472.0 | 37.22 | 37.2 | Interoception: the sense of the physiological condition of the body. | A D Craig | Curr Opin Neurobiol | 2003 | 12965300 | No |
2080 | 1471 | 1471.0 | 34.64 | 34.6 | Oxidative stress in Parkinson's disease. | Peter Jenner | Ann Neurol | 2003 | 12666096 | No |
2081 | 2940 | 1470.0 | 91.92 | 46.0 | Modified RECIST (mRECIST) assessment for hepatocellular carcinoma. | Riccardo Lencioni, Josep M Llovet | Semin Liver Dis | 2010 | 20175033 | No |
2082 | 1469 | 1469.0 | 70.79 | 70.8 | Chronic illness as biographical disruption. | M Bury | Sociol Health Illn | 1982 | 10260456 | Yes |
2083 | 1469 | 1469.0 | 7.64 | 7.6 | Electron Microscope Studies On The Structure Of Natural And Synthetic Protein Filaments From Striated Muscle. | H E Huxley | J Mol Biol | 1963 | 14064165 | Yes |
2084 | 1468 | 1468.0 | 38.43 | 38.4 | Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. | Michael F Holick | Am J Clin Nutr | 2004 | 15585788 | No |
2085 | 13206 | 1467.3 | 405.46 | 45.1 | The 1982 revised criteria for the classification of systemic lupus erythematosus. | E M Tan, A S Cohen, J F Fries, A T Masi, D J McShane, N F Rothfield, J G Schaller, N Talal, R J Winchester | Arthritis Rheum | 1982 | 7138600 | Yes |
2086 | 4402 | 1467.3 | 93.02 | 31.0 | TOR signaling in growth and metabolism. | Stephan Wullschleger, Robbie Loewith, Michael N Hall | Cell | 2006 | 16469695 | No |
2087 | 1467 | 1467.0 | 33.37 | 33.4 | Simple methods for "staining with lead" at high pH in electron microscopy. | M J Karnovsky | J Biophys Biochem Cytol | 1961 | 14454024 | Yes |
2088 | 1467 | 1467.0 | 36.07 | 36.1 | Fast and robust fixed-point algorithms for independent component analysis. | A Hyvärinen | IEEE Trans Neural Netw | 1999 | 18252563 | Yes |
2089 | 1466 | 1466.0 | 45.57 | 45.6 | The Neuropsychiatric Inventory: assessing psychopathology in dementia patients. | J L Cummings | Neurology | 1997 | 9153155 | No |
2090 | 1466 | 1466.0 | 31.17 | 31.2 | Topoisomerase I inhibitors: camptothecins and beyond. | Yves Pommier | Nat Rev Cancer | 2006 | 16990856 | No |
2091 | 5862 | 1465.5 | 128.24 | 32.1 | Probability-based protein identification by searching sequence databases using mass spectrometry data. | D N Perkins, D J Pappin, D M Creasy, J S Cottrell | Electrophoresis | 1999 | 10612281 | Yes |
2092 | 1465 | 1465.0 | 54.27 | 54.3 | Cardiac valve surgery--the "French correction". | A Carpentier | J Thorac Cardiovasc Surg | 1983 | 6887954 | Yes |
2093 | 1465 | 1465.0 | 40.19 | 40.2 | Leishmaniasis: current situation and new perspectives. | P Desjeux | Comp Immunol Microbiol Infect Dis | 2004 | 15225981 | No |
2094 | 1465 | 1465.0 | 31.5 | 31.5 | Autophagy: from phenomenology to molecular understanding in less than a decade. | Daniel J Klionsky | Nat Rev Mol Cell Biol | 2007 | 17712358 | No |
2095 | 1464 | 1464.0 | 0.0 | 0.0 | Modality and topographic properties of single neurons of cat's somatic sensory cortex. | V B Mountcastle | J Neurophysiol | 1957 | 13439410 | Yes |
2096 | 1464 | 1464.0 | 0.0 | 0.0 | The free amino groups of insulin. | F Sanger | Biochem J | 1945 | 16747948 | Yes |
2097 | 2927 | 1463.5 | 86.53 | 43.3 | From best evidence to best practice: effective implementation of change in patients' care. | Richard Grol, Jeremy Grimshaw | Lancet | 2003 | 14568747 | No |
2098 | 1462 | 1462.0 | 45.09 | 45.1 | Equipoise and the ethics of clinical research. | B Freedman | N Engl J Med | 1987 | 3600702 | Yes |
2099 | 1462 | 1462.0 | 33.86 | 33.9 | PPAR-gamma: adipogenic regulator and thiazolidinedione receptor. | B M Spiegelman | Diabetes | 1998 | 9568680 | No |
2100 | 1462 | 1462.0 | 0.0 | 0.0 | Methods of paper chromatography of steroids applicable to the study of steroids in mammalian blood and tissues. | I E Bush | Biochem J | 1952 | 14915960 | Yes |
2101 | 4385 | 1461.7 | 35.48 | 11.8 | Improved method for the determination of blood glutathione. | E Beutler, O Duron, B M Kelly | J Lab Clin Med | 1963 | 13967893 | Yes |
2102 | 2923 | 1461.5 | 38.87 | 19.4 | The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation. | E G Gray, V P Whittaker | J Anat | 1962 | 13901297 | Yes |
2103 | 2923 | 1461.5 | 113.67 | 56.8 | Elements of cancer immunity and the cancer-immune set point. | Daniel S Chen, Ira Mellman | Nature | 2017 | 28102259 | No |
2104 | 1461 | 1461.0 | 34.41 | 34.4 | Binary Agrobacterium vectors for plant transformation. | M Bevan | Nucleic Acids Res | 1984 | 6095209 | Yes |
2105 | 1461 | 1461.0 | 0.0 | 0.0 | The Function Of The Vertebral Veins And Their Role In The Spread Of Metastases. | O V Batson | Ann Surg | 1940 | 17857618 | Yes |
2106 | 1460 | 1460.0 | 36.05 | 36.0 | Microbial ecology of the gastrointestinal tract. | D C Savage | Annu Rev Microbiol | 1977 | 334036 | No |
2107 | 1460 | 1460.0 | 26.76 | 26.8 | The Relation Of Recombination To Mutational Advance. | H J Muller | Mutat Res | 1964 | 14195748 | Yes |
2108 | 2917 | 1458.5 | 85.8 | 42.9 | The cortical organization of speech processing. | Gregory Hickok, David Poeppel | Nat Rev Neurosci | 2007 | 17431404 | No |
2109 | 1458 | 1458.0 | 28.97 | 29.0 | The organization of proteins in the human red blood cell membrane. A review. | T L Steck | J Cell Biol | 1974 | 4600883 | No |
2110 | 2914 | 1457.0 | 0.0 | 0.0 | Techniques for hemagglutination and hemagglutination-inhibition with arthropod-borne viruses. | D H Clarke, J Casals | Am J Trop Med Hyg | 1958 | 13571577 | Yes |
2111 | 13110 | 1456.7 | 403.01 | 44.8 | The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. | D V Sheehan, Y Lecrubier, K H Sheehan, P Amorim, J Janavs, E Weiller, T Hergueta, R Baker, G C Dunbar | J Clin Psychiatry | 1998 | 9881538 | No |
2112 | 2913 | 1456.5 | 60.54 | 30.3 | Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry. | Joshua E Elias, Steven P Gygi | Nat Methods | 2007 | 17327847 | Yes |
2113 | 4368 | 1456.0 | 95.18 | 31.7 | Telomeres shorten during ageing of human fibroblasts. | C B Harley, A B Futcher, C W Greider | Nature | 1990 | 2342578 | Yes |
2114 | 2912 | 1456.0 | 85.18 | 42.6 | Mediation in experimental and nonexperimental studies: new procedures and recommendations. | Patrick E Shrout, Niall Bolger | Psychol Methods | 2002 | 12530702 | Yes |
2115 | 1456 | 1456.0 | 41.39 | 41.4 | The Hospital Anxiety And Depression Scale. | R Philip Snaith | Health Qual Life Outcomes | 2003 | 12914662 | Yes |
2116 | 1456 | 1456.0 | 33.8 | 33.8 | Phytohemagglutinin: an initiator of mitosis in cultures of normal human leukocytes. | P C Nowell | Cancer Res | 1960 | 14427849 | Yes |
2117 | 10191 | 1455.9 | 285.49 | 40.8 | BLAST+: architecture and applications. | Christiam Camacho, George Coulouris, Vahram Avagyan, Ning Ma, Jason Papadopoulos, Kevin Bealer, Thomas L Madden | BMC Bioinformatics | 2009 | 20003500 | Yes |
2118 | 2911 | 1455.5 | 99.26 | 49.6 | Assay of proteins in the presence of interfering materials. | A Bensadoun, D Weinstein | Anal Biochem | 1976 | 1259145 | Yes |
2119 | 4363 | 1454.3 | 109.68 | 36.6 | The metabolic syndrome. | Robert H Eckel, Scott M Grundy, Paul Z Zimmet | Lancet | 2005 | 15836891 | No |
2120 | 1454 | 1454.0 | 49.84 | 49.8 | Assessing self-maintenance: activities of daily living, mobility, and instrumental activities of daily living. | S Katz | J Am Geriatr Soc | 1983 | 6418786 | No |
2121 | 1454 | 1454.0 | 0.0 | 0.0 | A modified ninhydrin colorimetric analysis for amino acids. | H Rosen | Arch Biochem Biophys | 1957 | 13412116 | Yes |
2122 | 1454 | 1454.0 | 0.0 | 0.0 | Potential, Impedance, And Rectification In Membranes. | D E Goldman | J Gen Physiol | 1943 | 19873371 | Yes |
2123 | 2906 | 1453.0 | 66.29 | 33.1 | Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA. | C Auffray, F Rougeon | Eur J Biochem | 1980 | 6772444 | Yes |
2124 | 2906 | 1453.0 | 77.54 | 38.8 | Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. | B R Celli, W MacNee | Eur Respir J | 2004 | 15219010 | No |
2125 | 4358 | 1452.7 | 132.41 | 44.1 | Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. | S van der Linden, H A Valkenburg, A Cats | Arthritis Rheum | 1984 | 6231933 | Yes |
2126 | 2904 | 1452.0 | 74.51 | 37.3 | Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. | I Issemann, S Green | Nature | 1990 | 2129546 | Yes |
2127 | 1452 | 1452.0 | 35.49 | 35.5 | General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids. | R A Houghten | Proc Natl Acad Sci U S A | 1985 | 2410914 | Yes |
2128 | 2904 | 1452.0 | 67.28 | 33.6 | The MAPK signaling cascade. | R Seger, E G Krebs | FASEB J | 1995 | 7601337 | No |
2129 | 2904 | 1452.0 | 57.88 | 28.9 | Intrinsically unstructured proteins and their functions. | H Jane Dyson, Peter E Wright | Nat Rev Mol Cell Biol | 2005 | 15738986 | No |
2130 | 1452 | 1452.0 | 44.04 | 44.0 | The functional gastrointestinal disorders and the Rome III process. | Douglas A Drossman | Gastroenterology | 2006 | 16678553 | No |
2131 | 1452 | 1452.0 | 72.29 | 72.3 | International classification of sleep disorders-third edition: highlights and modifications. | Michael J Sateia | Chest | 2014 | 25367475 | No |
2132 | 2903 | 1451.5 | 90.87 | 45.4 | Functional architecture of basal ganglia circuits: neural substrates of parallel processing. | G E Alexander, M D Crutcher | Trends Neurosci | 1990 | 1695401 | No |
2133 | 1451 | 1451.0 | 48.43 | 48.4 | Analysis of radioligand binding experiments. A collection of computer programs for the IBM PC. | G A McPherson | J Pharmacol Methods | 1985 | 3840547 | Yes |
2134 | 1451 | 1451.0 | 19.55 | 19.6 | Codon--anticodon pairing: the wobble hypothesis. | F H Crick | J Mol Biol | 1966 | 5969078 | Yes |
2135 | 1451 | 1451.0 | 46.06 | 46.1 | A clinical method for assessing the ventilatory response to carbon dioxide. | D J Read | Australas Ann Med | 1967 | 6032026 | Yes |
2136 | 1451 | 1451.0 | 31.61 | 31.6 | Protein misfolding, evolution and disease. | C M Dobson | Trends Biochem Sci | 1999 | 10470028 | No |
2137 | 5803 | 1450.8 | 180.44 | 45.1 | The unlabeled antibody enzyme method of immunohistochemistry: preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes. | L A Sternberger, P H Hardy, J J Cuculis, H G Meyer | J Histochem Cytochem | 1970 | 4192899 | Yes |
2138 | 1450 | 1450.0 | 36.25 | 36.2 | Stress and hippocampal plasticity. | B S McEwen | Annu Rev Neurosci | 1999 | 10202533 | No |
2139 | 1450 | 1450.0 | 40.78 | 40.8 | Treatment of infections associated with surgical implants. | Rabih O Darouiche | N Engl J Med | 2004 | 15070792 | No |
2140 | 2899 | 1449.5 | 94.39 | 47.2 | Peptidoglycan types of bacterial cell walls and their taxonomic implications. | K H Schleifer, O Kandler | Bacteriol Rev | 1972 | 4568761 | No |
2141 | 2899 | 1449.5 | 79.25 | 39.6 | A rapid boiling method for the preparation of bacterial plasmids. | D S Holmes, M Quigley | Anal Biochem | 1981 | 6269464 | Yes |
2142 | 4347 | 1449.0 | 92.69 | 30.9 | NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. | S Ghosh, M J May, E B Kopp | Annu Rev Immunol | 1998 | 9597130 | No |
2143 | 1449 | 1449.0 | 30.6 | 30.6 | Neurotrophins as synaptic modulators. | M M Poo | Nat Rev Neurosci | 2001 | 11253356 | No |
2144 | 1449 | 1449.0 | 36.27 | 36.3 | Wound healing and its impairment in the diabetic foot. | Vincent Falanga | Lancet | 2005 | 16291068 | No |
2145 | 1449 | 1449.0 | 32.87 | 32.9 | Cell signaling. H2O2, a necessary evil for cell signaling. | Sue Goo Rhee | Science | 2006 | 16809515 | Yes |
2146 | 2896 | 1448.0 | 72.09 | 36.0 | 3' non-coding region sequences in eukaryotic messenger RNA. | N J Proudfoot, G G Brownlee | Nature | 1976 | 822353 | Yes |
2147 | 1448 | 1448.0 | 33.57 | 33.6 | Developmental cell death: morphological diversity and multiple mechanisms. | P G Clarke | Anat Embryol (Berl) | 1990 | 2186664 | No |
2148 | 1448 | 1448.0 | 74.51 | 74.5 | The determinants of parenting: a process model. | J Belsky | Child Dev | 1984 | 6705636 | Yes |
2149 | 1447 | 1447.0 | 0.0 | 0.0 | Starch gel electrophoresis in a discontinous system of buffers. | M D Poulik | Nature | 1957 | 13493570 | Yes |
2150 | 1447 | 1447.0 | 42.41 | 42.4 | Variations in patients' adherence to medical recommendations: a quantitative review of 50 years of research. | M Robin DiMatteo | Med Care | 2004 | 15076819 | Yes |
2151 | 1447 | 1447.0 | 35.51 | 35.5 | The amygdala modulates the consolidation of memories of emotionally arousing experiences. | James L McGaugh | Annu Rev Neurosci | 2004 | 15217324 | No |
2152 | 1446 | 1446.0 | 42.47 | 42.5 | Human cardiovascular adjustments to exercise and thermal stress. | L B Rowell | Physiol Rev | 1974 | 4587247 | No |
2153 | 1446 | 1446.0 | 31.68 | 31.7 | Mitochondria: dynamic organelles in disease, aging, and development. | David C Chan | Cell | 2006 | 16814712 | No |
2154 | 2889 | 1444.5 | 57.96 | 29.0 | A study of the factors affecting the aluminum oxide-trihydroxyindole procedure for the analysis of catecholamines. | A H Anton, D F Sayre | J Pharmacol Exp Ther | 1962 | 14013351 | Yes |
2155 | 2889 | 1444.5 | 109.5 | 54.8 | A new initiative on precision medicine. | Francis S Collins, Harold Varmus | N Engl J Med | 2015 | 25635347 | Yes |
2156 | 1444 | 1444.0 | 117.67 | 117.7 | User's guide to correlation coefficients. | Haldun Akoglu | Turk J Emerg Med | 2018 | 30191186 | No |
2157 | 1443 | 1443.0 | 50.42 | 50.4 | Phase retrieval algorithms: a comparison. | J R Fienup | Appl Opt | 1982 | 20396114 | Yes |
2158 | 12987 | 1443.0 | 632.92 | 70.3 | Cancer statistics in China, 2015. | Wanqing Chen, Rongshou Zheng, Peter D Baade, Siwei Zhang, Hongmei Zeng, Freddie Bray, Ahmedin Jemal, Xue Qin Yu, Jie He | CA Cancer J Clin | 2016 | 26808342 | Yes |
2159 | 2883 | 1441.5 | 85.87 | 42.9 | The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. | J D Hayes, D J Pulford | Crit Rev Biochem Mol Biol | 1995 | 8770536 | No |
2160 | 2883 | 1441.5 | 0.0 | 0.0 | Mutants of Escherichia coli requiring methionine or vitamin B12. | B D Davis, E S Mingioli | J Bacteriol | 1950 | 15436457 | Yes |
2161 | 1441 | 1441.0 | 57.14 | 57.1 | An outpatient program in behavioral medicine for chronic pain patients based on the practice of mindfulness meditation: theoretical considerations and preliminary results. | J Kabat-Zinn | Gen Hosp Psychiatry | 1982 | 7042457 | Yes |
2162 | 1441 | 1441.0 | 37.71 | 37.7 | The world health report 2002 - reducing risks, promoting healthy life. | J J Guilbert | Educ Health (Abingdon) | 2003 | 14741909 | Yes |
2163 | 15843 | 1440.3 | 418.55 | 38.1 | The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. | Aaron McKenna, Matthew Hanna, Eric Banks, Andrey Sivachenko, Kristian Cibulskis, Andrew Kernytsky, Kiran Garimella, David Altshuler, Stacey Gabriel, Mark Daly, Mark A DePristo | Genome Res | 2010 | 20644199 | Yes |
2164 | 1440 | 1440.0 | 37.06 | 37.1 | Capacitative calcium entry revisited. | J W Putney | Cell Calcium | 1990 | 1965707 | No |
2165 | 1440 | 1440.0 | 37.95 | 38.0 | Cell and environment interactions in tumor microregions: the multicell spheroid model. | R M Sutherland | Science | 1988 | 2451290 | Yes |
2166 | 4320 | 1440.0 | 260.91 | 87.0 | SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules. | Antoine Daina, Olivier Michielin, Vincent Zoete | Sci Rep | 2017 | 28256516 | Yes |
2167 | 1439 | 1439.0 | 56.44 | 56.4 | Reliability and factor analysis of the Epworth Sleepiness Scale. | M W Johns | Sleep | 1992 | 1519015 | Yes |
2168 | 1439 | 1439.0 | 29.56 | 29.6 | Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. | S S Ferguson | Pharmacol Rev | 2001 | 11171937 | No |
2169 | 2877 | 1438.5 | 78.15 | 39.1 | Angiogenesis. | J Folkman, Y Shing | J Biol Chem | 1992 | 1375931 | No |
2170 | 2876 | 1438.0 | 94.16 | 47.1 | The efficiency of systematic sampling in stereology and its prediction. | H J Gundersen, E B Jensen | J Microsc | 1987 | 3430576 | Yes |
2171 | 1438 | 1438.0 | 34.68 | 34.7 | Origin, biogenesis, and activity of plant microRNAs. | Olivier Voinnet | Cell | 2009 | 19239888 | No |
2172 | 1438 | 1438.0 | 31.52 | 31.5 | DNA damage, aging, and cancer. | Jan H J Hoeijmakers | N Engl J Med | 2009 | 19812404 | No |
2173 | 4308 | 1436.0 | 101.07 | 33.7 | Long non-coding RNAs: insights into functions. | Tim R Mercer, Marcel E Dinger, John S Mattick | Nat Rev Genet | 2009 | 19188922 | No |
2174 | 1436 | 1436.0 | 59.05 | 59.0 | Working memory: theories, models, and controversies. | Alan Baddeley | Annu Rev Psychol | 2012 | 21961947 | No |
2175 | 2871 | 1435.5 | 91.56 | 45.8 | Synchronization of Plasmodium falciparum erythrocytic stages in culture. | C Lambros, J P Vanderberg | J Parasitol | 1979 | 383936 | Yes |
2176 | 2870 | 1435.0 | 60.03 | 30.0 | The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. | M S Brown, J L Goldstein | Cell | 1997 | 9150132 | No |
2177 | 2870 | 1435.0 | 0.0 | 0.0 | Histological grading and prognosis in breast cancer; a study of 1409 cases of which 359 have been followed for 15 years. | H J Bloom, W W Richardson | Br J Cancer | 1957 | 13499785 | Yes |
2178 | 2870 | 1435.0 | 73.31 | 36.7 | Molecular replacement with MOLREP. | Alexei Vagin, Alexei Teplyakov | Acta Crystallogr D Biol Crystallogr | 2010 | 20057045 | Yes |
2179 | 4302 | 1434.0 | 114.01 | 38.0 | Fast model-based estimation of ancestry in unrelated individuals. | David H Alexander, John Novembre, Kenneth Lange | Genome Res | 2009 | 19648217 | Yes |
2180 | 1434 | 1434.0 | 40.32 | 40.3 | Graphene transistors. | Frank Schwierz | Nat Nanotechnol | 2010 | 20512128 | Yes |
2181 | 1433 | 1433.0 | 92.35 | 92.3 | The three column spine and its significance in the classification of acute thoracolumbar spinal injuries. | F Denis | Spine (Phila Pa 1976) | 1983 | 6670016 | Yes |
2182 | 1433 | 1433.0 | 0.0 | 0.0 | A new readability yardstick. | R Flesch | J Appl Psychol | 1948 | 18867058 | Yes |
2183 | 2865 | 1432.5 | 0.0 | 0.0 | Brain stem reticular formation and activation of the EEG. | G Moruzzi, H W Magoun | Electroencephalogr Clin Neurophysiol | 1949 | 18421835 | Yes |
2184 | 1432 | 1432.0 | 42.09 | 42.1 | Energy contributions of volatile fatty acids from the gastrointestinal tract in various species. | E N Bergman | Physiol Rev | 1990 | 2181501 | No |
2185 | 1432 | 1432.0 | 50.81 | 50.8 | The prevalence of 'alexithymic' characteristics in psychosomatic patients. | P E Sifneos | Psychother Psychosom | 1973 | 4770536 | Yes |
2186 | 1432 | 1432.0 | 34.1 | 34.1 | The use of nanocrystals in biological detection. | Paul Alivisatos | Nat Biotechnol | 2004 | 14704706 | Yes |
2187 | 2863 | 1431.5 | 67.35 | 33.7 | Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. | H Cai, D G Harrison | Circ Res | 2000 | 11073878 | No |
2188 | 2862 | 1431.0 | 54.08 | 27.0 | T-cell antigen receptor genes and T-cell recognition. | M M Davis, P J Bjorkman | Nature | 1988 | 3043226 | No |
2189 | 1431 | 1431.0 | 33.6 | 33.6 | Predictive values of body mass index and waist circumference for risk factors of certain related diseases in Chinese adults--study on optimal cut-off points of body mass index and waist circumference in Chinese adults. | Bei-Fan Zhou | Biomed Environ Sci | 2002 | 12046553 | Yes |
2190 | 1430 | 1430.0 | 41.78 | 41.8 | The fetal and infant origins of adult disease. | D J Barker | BMJ | 1990 | 2252919 | No |
2191 | 1430 | 1430.0 | 49.65 | 49.6 | Colorimetric determination of phospholipids with ammonium ferrothiocyanate. | J C Stewart | Anal Biochem | 1980 | 6892980 | Yes |
2192 | 1430 | 1430.0 | 42.46 | 42.5 | Strong localization of photons in certain disordered dielectric superlattices. | S John | Phys Rev Lett | 1987 | 10034761 | Yes |
2193 | 7145 | 1429.0 | 153.34 | 30.7 | Site-directed mutagenesis by overlap extension using the polymerase chain reaction. | S N Ho, H D Hunt, R M Horton, J K Pullen, L R Pease | Gene | 1989 | 2744487 | Yes |
2194 | 1429 | 1429.0 | 47.79 | 47.8 | Gene flow and the geographic structure of natural populations. | M Slatkin | Science | 1987 | 3576198 | Yes |
2195 | 4283 | 1427.7 | 84.06 | 28.0 | The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. | Fabio Martinon, Kimberly Burns, Jürg Tschopp | Mol Cell | 2002 | 12191486 | Yes |
2196 | 1427 | 1427.0 | 41.18 | 41.2 | The aging process. | D Harman | Proc Natl Acad Sci U S A | 1981 | 6947277 | Yes |
2197 | 1427 | 1427.0 | 33.34 | 33.3 | Functions of ceramide in coordinating cellular responses to stress. | Y A Hannun | Science | 1996 | 8943189 | No |
2198 | 4280 | 1426.7 | 88.11 | 29.4 | Toll-like receptors. | Kiyoshi Takeda, Tsuneyasu Kaisho, Shizuo Akira | Annu Rev Immunol | 2003 | 12524386 | No |
2199 | 17114 | 1426.2 | 718.67 | 59.9 | Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology. | Sue Richards, Nazneen Aziz, Sherri Bale, David Bick, Soma Das, Julie Gastier-Foster, Wayne W Grody, Madhuri Hegde, Elaine Lyon, Elaine Spector, Karl Voelkerding, Heidi L Rehm | Genet Med | 2015 | 25741868 | No |
2200 | 2851 | 1425.5 | 69.73 | 34.9 | Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. | E S Lander, D Botstein | Genetics | 1989 | 2563713 | Yes |
2201 | 2850 | 1425.0 | 58.38 | 29.2 | 'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease? | George Davey Smith, Shah Ebrahim | Int J Epidemiol | 2003 | 12689998 | No |
2202 | 1425 | 1425.0 | 37.12 | 37.1 | Linked Functions And Reciprocal Effects In Hemoglobin: A Second Look. | J Wyman | Adv Protein Chem | 1964 | 14268785 | No |
2203 | 1425 | 1425.0 | 40.82 | 40.8 | Recent developments in isocyanide based multicomponent reactions in applied chemistry. | Alexander Dömling | Chem Rev | 2006 | 16402771 | No |
2204 | 11399 | 1424.9 | 283.92 | 35.5 | Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. | N Tzourio-Mazoyer, B Landeau, D Papathanassiou, F Crivello, O Etard, N Delcroix, B Mazoyer, M Joliot | Neuroimage | 2002 | 11771995 | Yes |
2205 | 1424 | 1424.0 | 93.45 | 93.5 | The Knee Society total knee arthroplasty roentgenographic evaluation and scoring system. | F C Ewald | Clin Orthop Relat Res | 1989 | 2805502 | Yes |
2206 | 2847 | 1423.5 | 96.55 | 48.3 | Selective loss of central cholinergic neurons in Alzheimer's disease. | P Davies, A J Maloney | Lancet | 1976 | 63862 | Yes |
2207 | 2847 | 1423.5 | 55.03 | 27.5 | Autophagy as a regulated pathway of cellular degradation. | D J Klionsky, S D Emr | Science | 2000 | 11099404 | No |
2208 | 1423 | 1423.0 | 35.27 | 35.3 | The 'effective number of codons' used in a gene. | F Wright | Gene | 1990 | 2110097 | Yes |
2209 | 1423 | 1423.0 | 26.68 | 26.7 | Ubiquitin-dependent protein degradation. | M Hochstrasser | Annu Rev Genet | 1996 | 8982460 | No |
2210 | 1423 | 1423.0 | 25.73 | 25.7 | The DNA methyltransferases of mammals. | T H Bestor | Hum Mol Genet | 2000 | 11005794 | No |
2211 | 1422 | 1422.0 | 36.14 | 36.1 | Hemispheric asymmetry reduction in older adults: the HAROLD model. | Roberto Cabeza | Psychol Aging | 2002 | 11931290 | No |
2212 | 4265 | 1421.7 | 222.14 | 74.0 | Radiomics: Images Are More than Pictures, They Are Data. | Robert J Gillies, Paul E Kinahan, Hedvig Hricak | Radiology | 2016 | 26579733 | Yes |
2213 | 2843 | 1421.5 | 144.31 | 72.2 | A simple practice guide for dose conversion between animals and human. | Anroop B Nair, Shery Jacob | J Basic Clin Pharm | 2016 | 27057123 | No |
2214 | 1421 | 1421.0 | 41.12 | 41.1 | Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. | Charles A Dinarello | Blood | 2011 | 21304099 | No |
2215 | 1420 | 1420.0 | 51.52 | 51.5 | Sodium ions, calcium ions, blood pressure regulation, and hypertension: a reassessment and a hypothesis. | M P Blaustein | Am J Physiol | 1977 | 324293 | No |
2216 | 1420 | 1420.0 | 43.41 | 43.4 | Biological basis of the behavior of sick animals. | B L Hart | Neurosci Biobehav Rev | 1988 | 3050629 | No |
2217 | 2840 | 1420.0 | 55.01 | 27.5 | Cancer genes and the pathways they control. | Bert Vogelstein, Kenneth W Kinzler | Nat Med | 2004 | 15286780 | No |
2218 | 1420 | 1420.0 | 44.85 | 44.9 | Formation of glasses from liquids and biopolymers. | C A Angell | Science | 1995 | 17770101 | Yes |
2219 | 5680 | 1420.0 | 262.43 | 65.6 | Prevalence of childhood and adult obesity in the United States, 2011-2012. | Cynthia L Ogden, Margaret D Carroll, Brian K Kit, Katherine M Flegal | JAMA | 2014 | 24570244 | Yes |
2220 | 2839 | 1419.5 | 84.22 | 42.1 | Intracellular pH. | A Roos, W F Boron | Physiol Rev | 1981 | 7012859 | No |
2221 | 5675 | 1418.8 | 165.58 | 41.4 | Reversible middle cerebral artery occlusion without craniectomy in rats. | E Z Longa, P R Weinstein, S Carlson, R Cummins | Stroke | 1989 | 2643202 | Yes |
2222 | 2836 | 1418.0 | 97.25 | 48.6 | The framing of decisions and the psychology of choice. | A Tversky, D Kahneman | Science | 1981 | 7455683 | Yes |
2223 | 5671 | 1417.8 | 144.72 | 36.2 | Microbial ecology: human gut microbes associated with obesity. | Ruth E Ley, Peter J Turnbaugh, Samuel Klein, Jeffrey I Gordon | Nature | 2006 | 17183309 | Yes |
2224 | 4252 | 1417.3 | 140.84 | 46.9 | Vascular endothelial cells synthesize nitric oxide from L-arginine. | R M Palmer, D S Ashton, S Moncada | Nature | 1988 | 3131684 | Yes |
2225 | 2834 | 1417.0 | 68.17 | 34.1 | Decision curve analysis: a novel method for evaluating prediction models. | Andrew J Vickers, Elena B Elkin | Med Decis Making | 2006 | 17099194 | Yes |
2226 | 2833 | 1416.5 | 107.97 | 54.0 | Conn: a functional connectivity toolbox for correlated and anticorrelated brain networks. | Susan Whitfield-Gabrieli, Alfonso Nieto-Castanon | Brain Connect | 2012 | 22642651 | Yes |
2227 | 1416 | 1416.0 | 42.74 | 42.7 | Mate selection-a selection for a handicap. | A Zahavi | J Theor Biol | 1975 | 1195756 | Yes |
2228 | 1416 | 1416.0 | 56.38 | 56.4 | Social phobia. | M R Liebowitz | Mod Probl Pharmacopsychiatry | 1987 | 2885745 | Yes |
2229 | 2832 | 1416.0 | 72.1 | 36.0 | Morris water maze: procedures for assessing spatial and related forms of learning and memory. | Charles V Vorhees, Michael T Williams | Nat Protoc | 2006 | 17406317 | Yes |
2230 | 1415 | 1415.0 | 33.45 | 33.5 | Proinflammatory cytokines. | C A Dinarello | Chest | 2000 | 10936147 | No |
2231 | 2830 | 1415.0 | 0.0 | 0.0 | Virus interference. I. The interferon. | A Isaacs, J Lindenmann | Proc R Soc Lond B Biol Sci | 1957 | 13465720 | Yes |
2232 | 1415 | 1415.0 | 32.28 | 32.3 | Nonaqueous liquid electrolytes for lithium-based rechargeable batteries. | Kang Xu | Chem Rev | 2004 | 15669157 | Yes |
2233 | 1414 | 1414.0 | 22.86 | 22.9 | Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis. | K S McCully | Am J Pathol | 1969 | 5792556 | Yes |
2234 | 1414 | 1414.0 | 26.36 | 26.4 | NK cell receptors. | L L Lanier | Annu Rev Immunol | 1998 | 9597134 | No |
2235 | 1414 | 1414.0 | 26.99 | 27.0 | The significance of responses of the genome to challenge. | B McClintock | Science | 1984 | 15739260 | No |
2236 | 2827 | 1413.5 | 79.39 | 39.7 | Defining the clinical course of multiple sclerosis: results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. | F D Lublin, S C Reingold | Neurology | 1996 | 8780061 | Yes |
2237 | 2827 | 1413.5 | 118.76 | 59.4 | 3D bioprinting of tissues and organs. | Sean V Murphy, Anthony Atala | Nat Biotechnol | 2014 | 25093879 | Yes |
2238 | 1413 | 1413.0 | 35.26 | 35.3 | Solute perturbation of protein fluorescence. The quenching of the tryptophyl fluorescence of model compounds and of lysozyme by iodide ion. | S S Lehrer | Biochemistry | 1971 | 5119250 | Yes |
2239 | 2826 | 1413.0 | 56.5 | 28.2 | Short-term synaptic plasticity. | Robert S Zucker, Wade G Regehr | Annu Rev Physiol | 2002 | 11826273 | No |
2240 | 1413 | 1413.0 | 48.36 | 48.4 | Quantitative Genetic Analysis Of Multivariate Evolution, Applied To Brain:Body Size Allometry. | Russell Lande | Evolution | 1979 | 28568194 | Yes |
2241 | 1412 | 1412.0 | 59.62 | 59.6 | The self-medication hypothesis of addictive disorders: focus on heroin and cocaine dependence. | E J Khantzian | Am J Psychiatry | 1985 | 3904487 | No |
2242 | 1412 | 1412.0 | 39.72 | 39.7 | Isolation and cultivation of Lyme disease spirochetes. | A G Barbour | Yale J Biol Med | 1984 | 6393604 | Yes |
2243 | 1412 | 1412.0 | 36.08 | 36.1 | The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. | T Szkudelski | Physiol Res | 2001 | 11829314 | No |
2244 | 1412 | 1412.0 | 42.2 | 42.2 | The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. | Artemis P Simopoulos | Exp Biol Med (Maywood) | 2008 | 18408140 | No |
2245 | 2821 | 1410.5 | 121.85 | 60.9 | Sex differences in immune responses. | Sabra L Klein, Katie L Flanagan | Nat Rev Immunol | 2016 | 27546235 | No |
2246 | 2820 | 1410.0 | 71.66 | 35.8 | A globally coherent fingerprint of climate change impacts across natural systems. | Camille Parmesan, Gary Yohe | Nature | 2003 | 12511946 | Yes |
2247 | 2820 | 1410.0 | 0.0 | 0.0 | The effect of sodium ions on the electrical activity of giant axon of the squid. | A L Hodgkin, B Katz | J Physiol | 1949 | 18128147 | Yes |
2248 | 1410 | 1410.0 | 40.77 | 40.8 | Breakthrough of the year 2013. Cancer immunotherapy. | Jennifer Couzin-Frankel | Science | 2013 | 24357284 | No |
2249 | 1409 | 1409.0 | 32.88 | 32.9 | Speculations on the functions of the major heat shock and glucose-regulated proteins. | H R Pelham | Cell | 1986 | 2944601 | Yes |
2250 | 1409 | 1409.0 | 37.53 | 37.5 | A note on robust variance estimation for cluster-correlated data. | R L Williams | Biometrics | 2000 | 10877330 | Yes |
2251 | 1409 | 1409.0 | 52.06 | 52.1 | Diversity in tropical rain forests and coral reefs. | J H Connell | Science | 1978 | 17840770 | Yes |
2252 | 1409 | 1409.0 | 61.13 | 61.1 | Periodontitis: from microbial immune subversion to systemic inflammation. | George Hajishengallis | Nat Rev Immunol | 2015 | 25534621 | No |
2253 | 2816 | 1408.0 | 80.56 | 40.3 | Empirical predictions of protein conformation. | P Y Chou, G D Fasman | Annu Rev Biochem | 1978 | 354496 | No |
2254 | 1408 | 1408.0 | 33.5 | 33.5 | The basic science of gene therapy. | R C Mulligan | Science | 1993 | 8493530 | No |
2255 | 5628 | 1407.0 | 155.74 | 38.9 | Image quality assessment: from error visibility to structural similarity. | Zhou Wang, Alan Conrad Bovik, Hamid Rahim Sheikh, Eero P Simoncelli | IEEE Trans Image Process | 2004 | 15376593 | Yes |
2256 | 2813 | 1406.5 | 54.72 | 27.4 | Wnt signalling in stem cells and cancer. | Tannishtha Reya, Hans Clevers | Nature | 2005 | 15829953 | No |
2257 | 1406 | 1406.0 | 61.53 | 61.5 | A New Weighting System For Mean Surface Temperature Of The Human Body. | N L Ramanathan | J Appl Physiol | 1964 | 14173555 | Yes |
2258 | 2811 | 1405.5 | 52.45 | 26.2 | Oncogenic kinase signalling. | P Blume-Jensen, T Hunter | Nature | 2001 | 11357143 | No |
2259 | 2811 | 1405.5 | 72.53 | 36.3 | Alternative activation of macrophages: mechanism and functions. | Siamon Gordon, Fernando O Martinez | Immunity | 2010 | 20510870 | No |
2260 | 1405 | 1405.0 | 36.04 | 36.0 | The intraclass correlation coefficient as a measure of reliability. | J J Bartko | Psychol Rep | 1966 | 5942109 | Yes |
2261 | 2810 | 1405.0 | 77.06 | 38.5 | Transforming growth factor beta in tissue fibrosis. | W A Border, N A Noble | N Engl J Med | 1994 | 7935686 | No |
2262 | 2808 | 1404.0 | 87.83 | 43.9 | Performing the exact test of Hardy-Weinberg proportion for multiple alleles. | S W Guo, E A Thompson | Biometrics | 1992 | 1637966 | Yes |
2263 | 1404 | 1404.0 | 25.49 | 25.5 | Selection of successive tumour lines for metastasis. | I J Fidler | Nat New Biol | 1973 | 4512654 | Yes |
2264 | 4212 | 1404.0 | 146.47 | 48.8 | Structure-antioxidant activity relationships of flavonoids and phenolic acids. | C A Rice-Evans, N J Miller, G Paganga | Free Radic Biol Med | 1996 | 8743980 | Yes |
2265 | 1404 | 1404.0 | 35.29 | 35.3 | Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides. | Y Shai | Biochim Biophys Acta | 1999 | 10590302 | No |
2266 | 1404 | 1404.0 | 36.73 | 36.7 | The epidemiology of venous thromboembolism. | Richard H White | Circulation | 2003 | 12814979 | No |
2267 | 1404 | 1404.0 | 39.0 | 39.0 | The debate over dopamine's role in reward: the case for incentive salience. | Kent C Berridge | Psychopharmacology (Berl) | 2007 | 17072591 | No |
2268 | 4212 | 1404.0 | 120.89 | 40.3 | Dose translation from animal to human studies revisited. | Shannon Reagan-Shaw, Minakshi Nihal, Nihal Ahmad | FASEB J | 2008 | 17942826 | Yes |
2269 | 2806 | 1403.0 | 69.64 | 34.8 | Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule. | M D Pierschbacher, E Ruoslahti | Nature | 1984 | 6325925 | Yes |
2270 | 1403 | 1403.0 | 62.68 | 62.7 | Adjustments to Zatsiorsky-Seluyanov's segment inertia parameters. | P de Leva | J Biomech | 1996 | 8872282 | Yes |
2271 | 4207 | 1402.3 | 85.41 | 28.5 | Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM). | Michael J Rust, Mark Bates, Xiaowei Zhuang | Nat Methods | 2006 | 16896339 | Yes |
2272 | 1402 | 1402.0 | 45.94 | 45.9 | Overcoming the absence of socioeconomic data in medical records: validation and application of a census-based methodology. | N Krieger | Am J Public Health | 1992 | 1566949 | Yes |
2273 | 1402 | 1402.0 | 50.34 | 50.3 | Categorical Data Analysis: Away from ANOVAs (transformation or not) and towards Logit Mixed Models. | T Florian Jaeger | J Mem Lang | 2008 | 19884961 | Yes |
2274 | 2803 | 1401.5 | 71.04 | 35.5 | CLUSTAL: a package for performing multiple sequence alignment on a microcomputer. | D G Higgins, P M Sharp | Gene | 1988 | 3243435 | Yes |
2275 | 2803 | 1401.5 | 62.48 | 31.2 | Raster3D Version 2.0. A program for photorealistic molecular graphics. | E A Merritt, M E Murphy | Acta Crystallogr D Biol Crystallogr | 1994 | 15299354 | Yes |
2276 | 2802 | 1401.0 | 42.18 | 21.1 | Prediction of protein conformation. | P Y Chou, G D Fasman | Biochemistry | 1974 | 4358940 | Yes |
2277 | 1400 | 1400.0 | 32.03 | 32.0 | Protein kinase C: structure, function, and regulation. | A C Newton | J Biol Chem | 1995 | 7499357 | No |
2278 | 2800 | 1400.0 | 61.63 | 30.8 | An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. | A A Beg, D Baltimore | Science | 1996 | 8864118 | Yes |
2279 | 8396 | 1399.3 | 215.45 | 35.9 | Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. | Roy G Brower, Michael A Matthay, Alan Morris, David Schoenfeld, B Taylor Thompson, Arthur Wheeler | N Engl J Med | 2000 | 10793162 | Yes |
2280 | 2798 | 1399.0 | 69.76 | 34.9 | Molecular beacons: probes that fluoresce upon hybridization. | S Tyagi, F R Kramer | Nat Biotechnol | 1996 | 9630890 | Yes |
2281 | 2797 | 1398.5 | 61.97 | 31.0 | The pathophysiology and treatment of sepsis. | Richard S Hotchkiss, Irene E Karl | N Engl J Med | 2003 | 12519925 | No |
2282 | 2796 | 1398.0 | 69.55 | 34.8 | Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications. | Felix Krueger, Simon R Andrews | Bioinformatics | 2011 | 21493656 | Yes |
2283 | 2795 | 1397.5 | 85.72 | 42.9 | Unidentified curved bacilli on gastric epithelium in active chronic gastritis. | J R Warren, B Marshall | Lancet | 1983 | 6134060 | Yes |
2284 | 1397 | 1397.0 | 50.31 | 50.3 | The SPQ: a scale for the assessment of schizotypal personality based on DSM-III-R criteria. | A Raine | Schizophr Bull | 1991 | 1805349 | Yes |
2285 | 1397 | 1397.0 | 28.17 | 28.2 | The Interaction of Selection and Linkage. I. General Considerations; Heterotic Models. | R C Lewontin | Genetics | 1964 | 17248194 | Yes |
2286 | 2793 | 1396.5 | 110.87 | 55.4 | Cisplatin in cancer therapy: molecular mechanisms of action. | Shaloam Dasari, Paul Bernard Tchounwou | Eur J Pharmacol | 2014 | 25058905 | No |
2287 | 1395 | 1395.0 | 24.22 | 24.2 | The economics of ribosome biosynthesis in yeast. | J R Warner | Trends Biochem Sci | 1999 | 10542411 | No |
2288 | 2790 | 1395.0 | 88.73 | 44.4 | Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art. | Johan W S Vlaeyen, Steven J Linton | Pain | 2000 | 10781906 | No |
2289 | 1395 | 1395.0 | 33.36 | 33.4 | Drug-induced prolongation of the QT interval. | Dan M Roden | N Engl J Med | 2004 | 14999113 | No |
2290 | 2789 | 1394.5 | 82.46 | 41.2 | Glycine potentiates the NMDA response in cultured mouse brain neurons. | J W Johnson, P Ascher | Nature | 1987 | 2433595 | Yes |
2291 | 2786 | 1393.0 | 72.97 | 36.5 | Enzyme-linked immunosorbent assay (ELISA). Quantitative assay of immunoglobulin G. | E Engvall, P Perlmann | Immunochemistry | 1971 | 5135623 | Yes |
2292 | 1393 | 1393.0 | 30.52 | 30.5 | The ATP synthase--a splendid molecular machine. | P D Boyer | Annu Rev Biochem | 1997 | 9242922 | No |
2293 | 2786 | 1393.0 | 84.63 | 42.3 | An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. | O Johnell, J A Kanis | Osteoporos Int | 2006 | 16983459 | Yes |
2294 | 2785 | 1392.5 | 82.28 | 41.1 | Microdetermination of long-chain fatty acids in plasma and tissues. | V P Dole, H Meinertz | J Biol Chem | 1960 | 13817286 | Yes |
2295 | 1392 | 1392.0 | 52.78 | 52.8 | Presidential address, 1980. Surprise!...Surprise? | E Donchin | Psychophysiology | 1981 | 7280146 | Yes |
2296 | 2783 | 1391.5 | 148.64 | 74.3 | Social networks, host resistance, and mortality: a nine-year follow-up study of Alameda County residents. | L F Berkman, S L Syme | Am J Epidemiol | 1979 | 425958 | Yes |
2297 | 1391 | 1391.0 | 50.04 | 50.0 | Quantitative methods in the review of epidemiologic literature. | S Greenland | Epidemiol Rev | 1987 | 3678409 | Yes |
2298 | 4173 | 1391.0 | 121.32 | 40.4 | Validation of the Insomnia Severity Index as an outcome measure for insomnia research. | C H. Bastien, A Vallières, C M. Morin | Sleep Med | 2001 | 11438246 | Yes |
2299 | 1391 | 1391.0 | 29.62 | 29.6 | Cancer of the ovary. | Stephen A Cannistra | N Engl J Med | 2004 | 15590954 | No |
2300 | 1391 | 1391.0 | 34.74 | 34.7 | The cancer stem cell: premises, promises and challenges. | Hans Clevers | Nat Med | 2011 | 21386835 | No |
2301 | 2781 | 1390.5 | 80.47 | 40.2 | CLUMPP: a cluster matching and permutation program for dealing with label switching and multimodality in analysis of population structure. | Mattias Jakobsson, Noah A Rosenberg | Bioinformatics | 2007 | 17485429 | Yes |
2302 | 1389 | 1389.0 | 62.76 | 62.8 | Mechanisms linking social ties and support to physical and mental health. | Peggy A Thoits | J Health Soc Behav | 2011 | 21673143 | No |
2303 | 2777 | 1388.5 | 65.76 | 32.9 | Inflammation, stress, and diabetes. | Kathryn E Wellen, Gökhan S Hotamisligil | J Clin Invest | 2005 | 15864338 | No |
2304 | 1388 | 1388.0 | 28.31 | 28.3 | Origin of concatemeric T7 DNA. | J D Watson | Nat New Biol | 1972 | 4507727 | Yes |
2305 | 1388 | 1388.0 | 33.83 | 33.8 | Tobacco smoke carcinogens and lung cancer. | S S Hecht | J Natl Cancer Inst | 1999 | 10413421 | No |
2306 | 1388 | 1388.0 | 26.96 | 27.0 | Natively unfolded proteins: a point where biology waits for physics. | Vladimir N Uversky | Protein Sci | 2002 | 11910019 | No |
2307 | 1387 | 1387.0 | 35.11 | 35.1 | Diagnosis of osteoporosis and assessment of fracture risk. | John A Kanis | Lancet | 2002 | 12057569 | No |
2308 | 4161 | 1387.0 | 100.21 | 33.4 | Wnt/beta-catenin signaling: components, mechanisms, and diseases. | Bryan T MacDonald, Keiko Tamai, Xi He | Dev Cell | 2009 | 19619488 | No |
2309 | 2773 | 1386.5 | 63.5 | 31.8 | A method of trace iodination of proteins for immunologic studies. | P J McConahey, F J Dixon | Int Arch Allergy Appl Immunol | 1966 | 4160044 | Yes |
2310 | 2772 | 1386.0 | 62.15 | 31.1 | Immunoassay of endogenous plasma insulin in man. | R S Yalow, S A Berson | J Clin Invest | 1960 | 13846364 | Yes |
2311 | 5544 | 1386.0 | 204.53 | 51.1 | FieldTrip: Open source software for advanced analysis of MEG, EEG, and invasive electrophysiological data. | Robert Oostenveld, Pascal Fries, Eric Maris, Jan-Mathijs Schoffelen | Comput Intell Neurosci | 2011 | 21253357 | Yes |
2312 | 2771 | 1385.5 | 71.36 | 35.7 | A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments. | J Messing, J Vieira | Gene | 1982 | 6295880 | Yes |
2313 | 1385 | 1385.0 | 30.13 | 30.1 | Target-oriented and diversity-oriented organic synthesis in drug discovery. | S L Schreiber | Science | 2000 | 10720315 | No |
2314 | 4154 | 1384.7 | 111.21 | 37.1 | TCS: a computer program to estimate gene genealogies. | M Clement, D Posada, K A Crandall | Mol Ecol | 2000 | 11050560 | Yes |
2315 | 2769 | 1384.5 | 88.82 | 44.4 | The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. | W R Gibb, A J Lees | J Neurol Neurosurg Psychiatry | 1988 | 2841426 | No |
2316 | 2769 | 1384.5 | 81.09 | 40.5 | Physiological time-series analysis using approximate entropy and sample entropy. | J S Richman, J R Moorman | Am J Physiol Heart Circ Physiol | 2000 | 10843903 | Yes |
2317 | 4151 | 1383.7 | 194.08 | 64.7 | Risk factors for falls among elderly persons living in the community. | M E Tinetti, M Speechley, S F Ginter | N Engl J Med | 1988 | 3205267 | Yes |
2318 | 1383 | 1383.0 | 46.48 | 46.5 | Interleukin-1. | C A Dinarello | Rev Infect Dis | 1984 | 6369481 | No |
2319 | 4148 | 1382.7 | 87.73 | 29.2 | Multidrug resistance in cancer: role of ATP-dependent transporters. | Michael M Gottesman, Tito Fojo, Susan E Bates | Nat Rev Cancer | 2002 | 11902585 | No |
2320 | 1382 | 1382.0 | 18.71 | 18.7 | Hippocampal electrical activity and voluntary movement in the rat. | C H Vanderwolf | Electroencephalogr Clin Neurophysiol | 1969 | 4183562 | Yes |
2321 | 1382 | 1382.0 | 0.0 | 0.0 | Intracellular distribution of enzymes; the oxidation of octanoic acid by rat liver fractions. | W C Schneider | J Biol Chem | 1948 | 18886166 | Yes |
2322 | 1381 | 1381.0 | 31.33 | 31.3 | Molecular basis of long-term plasticity underlying addiction. | E J Nestler | Nat Rev Neurosci | 2001 | 11252991 | No |
2323 | 1380 | 1380.0 | 35.94 | 35.9 | Genetic consequences of climatic oscillations in the Quaternary. | G M Hewitt | Philos Trans R Soc Lond B Biol Sci | 2004 | 15101575 | No |
2324 | 4139 | 1379.7 | 83.63 | 27.9 | The versatility and universality of calcium signalling. | M J Berridge, P Lipp, M D Bootman | Nat Rev Mol Cell Biol | 2000 | 11413485 | No |
2325 | 1379 | 1379.0 | 30.63 | 30.6 | Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles. | M Kozak | Microbiol Rev | 1983 | 6343825 | No |
2326 | 2758 | 1379.0 | 79.98 | 40.0 | Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. | C J Murray, A D Lopez | Lancet | 1997 | 9164317 | Yes |
2327 | 2758 | 1379.0 | 67.15 | 33.6 | Powering the planet: chemical challenges in solar energy utilization. | Nathan S Lewis, Daniel G Nocera | Proc Natl Acad Sci U S A | 2006 | 17043226 | Yes |
2328 | 1379 | 1379.0 | 57.14 | 57.1 | The global burden of IBD: from 2015 to 2025. | Gilaad G Kaplan | Nat Rev Gastroenterol Hepatol | 2015 | 26323879 | No |
2329 | 6893 | 1378.6 | 254.81 | 51.0 | Evidence based medicine: what it is and what it isn't. | D L Sackett, W M Rosenberg, J A Gray, R B Haynes, W S Richardson | BMJ | 1996 | 8555924 | No |
2330 | 4133 | 1377.7 | 140.69 | 46.9 | Factor structure of the Barratt impulsiveness scale. | J H Patton, M S Stanford, E S Barratt | J Clin Psychol | 1995 | 8778124 | Yes |
2331 | 4133 | 1377.7 | 92.11 | 30.7 | OrthoMCL: identification of ortholog groups for eukaryotic genomes. | Li Li, Christian J Stoeckert, David S Roos | Genome Res | 2003 | 12952885 | Yes |
2332 | 4132 | 1377.3 | 136.5 | 45.5 | Global estimates of the prevalence of diabetes for 2010 and 2030. | J E Shaw, R A Sicree, P Z Zimmet | Diabetes Res Clin Pract | 2010 | 19896746 | Yes |
2333 | 1377 | 1377.0 | 58.85 | 58.9 | Refinement of the coomassie blue method of protein quantitation. A simple and linear spectrophotometric assay for less than or equal to 0.5 to 50 microgram of protein. | T Spector | Anal Biochem | 1978 | 655375 | Yes |
2334 | 1377 | 1377.0 | 24.37 | 24.4 | The snail superfamily of zinc-finger transcription factors. | M Angela Nieto | Nat Rev Mol Cell Biol | 2002 | 11994736 | No |
2335 | 1377 | 1377.0 | 29.29 | 29.3 | A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. | Dale R Nyholt | Am J Hum Genet | 2004 | 14997420 | Yes |
2336 | 1377 | 1377.0 | 43.99 | 44.0 | The role of autophagy in neurodegenerative disease. | Ralph A Nixon | Nat Med | 2013 | 23921753 | No |
2337 | 2753 | 1376.5 | 99.35 | 49.7 | Biology of disease: free radicals and tissue injury. | B A Freeman, J D Crapo | Lab Invest | 1982 | 6290784 | No |
2338 | 2752 | 1376.0 | 95.1 | 47.5 | A new scale of social desirability independent of psychopathology. | D P Crowne, D Marlowe | J Consult Psychol | 1960 | 13813058 | Yes |
2339 | 1376 | 1376.0 | 43.65 | 43.6 | Amino acids: metabolism, functions, and nutrition. | Guoyao Wu | Amino Acids | 2009 | 19301095 | No |
2340 | 1376 | 1376.0 | 0.0 | 0.0 | The generalisation of student's problems when several different population variances are involved. | B L Welch | Biometrika | 1947 | 20287819 | Yes |
2341 | 2752 | 1376.0 | 109.21 | 54.6 | Natural products as sources of new drugs over the 30 years from 1981 to 2010. | David J Newman, Gordon M Cragg | J Nat Prod | 2012 | 22316239 | No |
2342 | 4127 | 1375.7 | 98.39 | 32.8 | Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. | Daniel Falush, Matthew Stephens, Jonathan K Pritchard | Genetics | 2003 | 12930761 | Yes |
2343 | 1375 | 1375.0 | 21.79 | 21.8 | Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction. | J R David | Proc Natl Acad Sci U S A | 1966 | 5229858 | Yes |
2344 | 8249 | 1374.8 | 270.54 | 45.1 | Antioxidant activity applying an improved ABTS radical cation decolorization assay. | R Re, N Pellegrini, A Proteggente, A Pannala, M Yang, C Rice-Evans | Free Radic Biol Med | 1999 | 10381194 | Yes |
2345 | 2749 | 1374.5 | 70.33 | 35.2 | Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins. | D Marion, K Wüthrich | Biochem Biophys Res Commun | 1983 | 6307308 | Yes |
2346 | 2749 | 1374.5 | 73.84 | 36.9 | Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. | Robert E W Hancock, Hans-Georg Sahl | Nat Biotechnol | 2006 | 17160061 | No |
2347 | 1374 | 1374.0 | 39.15 | 39.1 | Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation. | P Willner | Psychopharmacology (Berl) | 1997 | 9452163 | No |
2348 | 5491 | 1372.8 | 211.59 | 52.9 | Bayesian phylogenetics with BEAUti and the BEAST 1.7. | Alexei J Drummond, Marc A Suchard, Dong Xie, Andrew Rambaut | Mol Biol Evol | 2012 | 22367748 | Yes |
2349 | 1372 | 1372.0 | 28.3 | 28.3 | Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators. | R I Morimoto | Genes Dev | 1998 | 9869631 | No |
2350 | 1372 | 1372.0 | 0.0 | 0.0 | An improved procedure for starch-gel electrophoresis: further variations in the serum proteins of normal individuals. | O Smithies | Biochem J | 1959 | 13638269 | Yes |
2351 | 1372 | 1372.0 | 35.24 | 35.2 | The human orbitofrontal cortex: linking reward to hedonic experience. | Morten L Kringelbach | Nat Rev Neurosci | 2005 | 16136173 | No |
2352 | 2743 | 1371.5 | 55.21 | 27.6 | Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids. | A J Berk, P A Sharp | Cell | 1977 | 922889 | Yes |
2353 | 2743 | 1371.5 | 77.36 | 38.7 | Mortality by cause for eight regions of the world: Global Burden of Disease Study. | C J Murray, A D Lopez | Lancet | 1997 | 9142060 | Yes |
2354 | 1371 | 1371.0 | 31.9 | 31.9 | Huntington's disease. | Francis O Walker | Lancet | 2007 | 17240289 | No |
2355 | 2741 | 1370.5 | 67.9 | 34.0 | Myocardial reperfusion injury. | Derek M Yellon, Derek J Hausenloy | N Engl J Med | 2007 | 17855673 | No |
2356 | 1370 | 1370.0 | 32.21 | 32.2 | Regulation of differentiation of vascular smooth muscle cells. | G K Owens | Physiol Rev | 1995 | 7624392 | No |
2357 | 4109 | 1369.7 | 118.05 | 39.4 | Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins. | J Garnier, D J Osguthorpe, B Robson | J Mol Biol | 1978 | 642007 | Yes |
2358 | 2739 | 1369.5 | 93.37 | 46.7 | Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans. | D H Figurski, D R Helinski | Proc Natl Acad Sci U S A | 1979 | 377280 | Yes |
2359 | 1369 | 1369.0 | 37.44 | 37.4 | The pollution of the marine environment by plastic debris: a review. | José G B Derraik | Mar Pollut Bull | 2002 | 12405208 | No |
2360 | 1369 | 1369.0 | 54.02 | 54.0 | AliView: a fast and lightweight alignment viewer and editor for large datasets. | Anders Larsson | Bioinformatics | 2014 | 25095880 | Yes |
2361 | 1368 | 1368.0 | 46.98 | 47.0 | Multiple calcium channels and neuronal function. | R J Miller | Science | 1987 | 2432656 | No |
2362 | 1368 | 1368.0 | 42.4 | 42.4 | The projections of the ventral tegmental area and adjacent regions: a combined fluorescent retrograde tracer and immunofluorescence study in the rat. | L W Swanson | Brain Res Bull | 1982 | 6816390 | Yes |
2363 | 1368 | 1368.0 | 39.87 | 39.9 | Depression in late life: review and commentary. | Dan G Blazer | J Gerontol A Biol Sci Med Sci | 2003 | 12634292 | No |
2364 | 1368 | 1368.0 | 25.9 | 25.9 | Epithelial-mesenchymal transitions in development and pathologies. | Jean Paul Thiery | Curr Opin Cell Biol | 2003 | 14644200 | No |
2365 | 2736 | 1368.0 | 70.97 | 35.5 | EasySpin, a comprehensive software package for spectral simulation and analysis in EPR. | Stefan Stoll, Arthur Schweiger | J Magn Reson | 2006 | 16188474 | Yes |
2366 | 1367 | 1367.0 | 44.22 | 44.2 | Synopsis of some recent tactical application of bioisosteres in drug design. | Nicholas A Meanwell | J Med Chem | 2011 | 21413808 | Yes |
2367 | 2733 | 1366.5 | 82.24 | 41.1 | Estimating wealth effects without expenditure data--or tears: an application to educational enrollments in states of India. | D Filmer, L H Pritchett | Demography | 2001 | 11227840 | Yes |
2368 | 1366 | 1366.0 | 22.34 | 22.3 | Cancer. Addiction to oncogenes--the Achilles heal of cancer. | I Bernard Weinstein | Science | 2002 | 12098689 | No |
2369 | 1366 | 1366.0 | 64.74 | 64.7 | PLATON SQUEEZE: a tool for the calculation of the disordered solvent contribution to the calculated structure factors. | Anthony L Spek | Acta Crystallogr C Struct Chem | 2015 | 25567569 | Yes |
2370 | 6828 | 1365.6 | 198.08 | 39.6 | Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. | Ronald C Kessler, Wai Tat Chiu, Olga Demler, Kathleen R Merikangas, Ellen E Walters | Arch Gen Psychiatry | 2005 | 15939839 | Yes |
2371 | 2731 | 1365.5 | 85.13 | 42.6 | A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. | R L Juliano, V Ling | Biochim Biophys Acta | 1976 | 990323 | Yes |
2372 | 2731 | 1365.5 | 80.3 | 40.1 | The Measurement Of Selection On Correlated Characters. | Russell Lande, Stevan J Arnold | Evolution | 1983 | 28556011 | Yes |
2373 | 1364 | 1364.0 | 0.0 | 0.0 | Notes on continuous stochastic phenomena. | P A P Moran | Biometrika | 1950 | 15420245 | Yes |
2374 | 2726 | 1363.0 | 54.07 | 27.0 | Prediction of complete gene structures in human genomic DNA. | C Burge, S Karlin | J Mol Biol | 1997 | 9149143 | Yes |
2375 | 2726 | 1363.0 | 73.34 | 36.7 | Antibiotic resistance of bacteria in biofilms. | P S Stewart, J W Costerton | Lancet | 2001 | 11463434 | No |
2376 | 1363 | 1363.0 | 0.0 | 0.0 | Effects of varying the vehicle for OsO4 in tissue fixation. | J B Caulfield | J Biophys Biochem Cytol | 1957 | 13475399 | Yes |
2377 | 1362 | 1362.0 | 49.62 | 49.6 | The structure of beta-lactamases. | R P Ambler | Philos Trans R Soc Lond B Biol Sci | 1980 | 6109327 | Yes |
2378 | 1362 | 1362.0 | 34.33 | 34.3 | Mitochondrial fusion and fission in cell life and death. | Benedikt Westermann | Nat Rev Mol Cell Biol | 2010 | 21102612 | No |
2379 | 1362 | 1362.0 | 48.83 | 48.8 | The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles. | Eleonore Fröhlich | Int J Nanomedicine | 2012 | 23144561 | No |
2380 | 1361 | 1361.0 | 32.76 | 32.8 | Membrane protein structure prediction. Hydrophobicity analysis and the positive-inside rule. | G von Heijne | J Mol Biol | 1992 | 1593632 | Yes |
2381 | 1361 | 1361.0 | 64.43 | 64.4 | Molecular pathology of schizophrenia: more than one disease process? | T J Crow | Br Med J | 1980 | 6101544 | No |
2382 | 1361 | 1361.0 | 42.97 | 43.0 | Antecedent- and response-focused emotion regulation: divergent consequences for experience, expression, and physiology. | J J Gross | J Pers Soc Psychol | 1998 | 9457784 | Yes |
2383 | 2721 | 1360.5 | 52.21 | 26.1 | A protein sequenator. | P Edman, G Begg | Eur J Biochem | 1967 | 6059350 | Yes |
2384 | 2721 | 1360.5 | 57.77 | 28.9 | LTP and LTD: an embarrassment of riches. | Robert C Malenka, Mark F Bear | Neuron | 2004 | 15450156 | No |
2385 | 1360 | 1360.0 | 24.22 | 24.2 | Chromatin modification and epigenetic reprogramming in mammalian development. | En Li | Nat Rev Genet | 2002 | 12209141 | No |
2386 | 1360 | 1360.0 | 27.98 | 28.0 | Stability and flexibility of epigenetic gene regulation in mammalian development. | Wolf Reik | Nature | 2007 | 17522676 | No |
2387 | 1360 | 1360.0 | 41.0 | 41.0 | Cross-dehydrogenative coupling (CDC): exploring C-C bond formations beyond functional group transformations. | Chao-Jun Li | Acc Chem Res | 2009 | 19220064 | Yes |
2388 | 2719 | 1359.5 | 95.56 | 47.8 | A sensitive silver stain for detecting lipopolysaccharides in polyacrylamide gels. | C M Tsai, C E Frasch | Anal Biochem | 1982 | 6176137 | Yes |
2389 | 2717 | 1358.5 | 62.64 | 31.3 | NF-kappa B: ten years after. | P A Baeuerle, D Baltimore | Cell | 1996 | 8858144 | No |
2390 | 2717 | 1358.5 | 62.72 | 31.4 | Emerging roles of caspase-3 in apoptosis. | A G Porter, R U Jänicke | Cell Death Differ | 1999 | 10200555 | No |
2391 | 2717 | 1358.5 | 74.76 | 37.4 | miRBase: integrating microRNA annotation and deep-sequencing data. | Ana Kozomara, Sam Griffiths-Jones | Nucleic Acids Res | 2011 | 21037258 | Yes |
2392 | 2716 | 1358.0 | 55.65 | 27.8 | Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. | J M Kyriakis, J Avruch | Physiol Rev | 2001 | 11274345 | No |
2393 | 2716 | 1358.0 | 0.0 | 0.0 | The respiratory chain and oxidative phosphorylation. | B Chance, G R Williams | Adv Enzymol Relat Subj Biochem | 1956 | 13313307 | Yes |
2394 | 1358 | 1358.0 | 12.12 | 12.1 | Immunological function of the thymus. | J F Miller | Lancet | 1961 | 14474038 | Yes |
2395 | 1357 | 1357.0 | 27.15 | 27.1 | Dimerization of cell surface receptors in signal transduction. | C H Heldin | Cell | 1995 | 7834741 | No |
2396 | 1356 | 1356.0 | 36.02 | 36.0 | Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications. | P Lips | Endocr Rev | 2001 | 11493580 | No |
2397 | 1356 | 1356.0 | 31.23 | 31.2 | Two's company, three's a crowd: can H2S be the third endogenous gaseous transmitter? | Rui Wang | FASEB J | 2002 | 12409322 | Yes |
2398 | 8136 | 1356.0 | 241.57 | 40.3 | The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. | Erik von Elm, Douglas G Altman, Matthias Egger, Stuart J Pocock, Peter C Gøtzsche, Jan P Vandenbroucke | Lancet | 2007 | 18064739 | Yes |
2399 | 6778 | 1355.6 | 165.16 | 33.0 | Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. | Sarah Lewington, Robert Clarke, Nawab Qizilbash, Richard Peto, Rory Collins | Lancet | 2002 | 12493255 | Yes |
2400 | 2709 | 1354.5 | 66.37 | 33.2 | Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. | M P Lutolf, J A Hubbell | Nat Biotechnol | 2005 | 15637621 | No |
2401 | 1354 | 1354.0 | 42.93 | 42.9 | Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: a hypothesis for the etiology of schizophrenia. | A A Grace | Neuroscience | 1991 | 1676137 | No |
2402 | 1354 | 1354.0 | 25.58 | 25.6 | The origin of the genetic code. | F H Crick | J Mol Biol | 1968 | 4887876 | Yes |
2403 | 1354 | 1354.0 | 34.64 | 34.6 | The carbon dioxide hydration activity of carbonic anhydrase. I. Stop-flow kinetic studies on the native human isoenzymes B and C. | R G Khalifah | J Biol Chem | 1971 | 4994926 | Yes |
2404 | 1354 | 1354.0 | 52.82 | 52.8 | Blood gas calculator. | J W Severinghaus | J Appl Physiol | 1966 | 5912737 | Yes |
2405 | 1354 | 1354.0 | 29.92 | 29.9 | Diarylethenes for Memories and Switches. | Masahiro Irie | Chem Rev | 2000 | 11777416 | Yes |
2406 | 1354 | 1354.0 | 139.91 | 139.9 | A Review of Coronavirus Disease-2019 (COVID-19). | Tanu Singhal | Indian J Pediatr | 2020 | 32166607 | No |
2407 | 1353 | 1353.0 | 0.0 | 0.0 | An approximate distribution of estimates of variance components. | F E Satterthwaite | Biometrics | 1946 | 20287815 | Yes |
2408 | 1352 | 1352.0 | 43.36 | 43.4 | History of the Rochester Epidemiology Project. | L J Melton | Mayo Clin Proc | 1996 | 8594285 | No |
2409 | 4056 | 1352.0 | 35.93 | 12.0 | Cytochemistry and electron microscopy. The preservation of cellular ultrastructure and enzymatic activity by aldehyde fixation. | D D Sabatini, K Bensch, R J Barrnett | J Cell Biol | 1963 | 13975866 | Yes |
2410 | 2704 | 1352.0 | 58.91 | 29.5 | NMR View: A computer program for the visualization and analysis of NMR data. | B A Johnson, R A Blevins | J Biomol NMR | 1994 | 22911360 | Yes |
2411 | 2703 | 1351.5 | 67.51 | 33.8 | The neural basis of human error processing: reinforcement learning, dopamine, and the error-related negativity. | Clay B Holroyd, Michael G H Coles | Psychol Rev | 2002 | 12374324 | Yes |
2412 | 1351 | 1351.0 | 42.31 | 42.3 | Glutathione metabolism and its selective modification. | A Meister | J Biol Chem | 1988 | 3053703 | No |
2413 | 2702 | 1351.0 | 61.22 | 30.6 | Disruption of epithelial cell-matrix interactions induces apoptosis. | S M Frisch, H Francis | J Cell Biol | 1994 | 8106557 | Yes |
2414 | 4053 | 1351.0 | 90.63 | 30.2 | Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides. | Christian W Tornøe, Caspar Christensen, Morten Meldal | J Org Chem | 2002 | 11975567 | Yes |
2415 | 4053 | 1351.0 | 104.26 | 34.8 | Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. | Robert D Schreiber, Lloyd J Old, Mark J Smyth | Science | 2011 | 21436444 | No |
2416 | 8105 | 1350.8 | 204.08 | 34.0 | A default mode of brain function. | M E Raichle, A M MacLeod, A Z Snyder, W J Powers, D A Gusnard, G L Shulman | Proc Natl Acad Sci U S A | 2001 | 11209064 | Yes |
2417 | 2700 | 1350.0 | 124.97 | 62.5 | Glutathione peroxidase activity in selenium-deficient rat liver. | R A Lawrence, R F Burk | Biochem Biophys Res Commun | 1976 | 971321 | Yes |
2418 | 1350 | 1350.0 | 36.27 | 36.3 | Atopic dermatitis. | Thomas Bieber | N Engl J Med | 2008 | 18385500 | Yes |
2419 | 5397 | 1349.2 | 127.46 | 31.9 | The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling. | Konstantin Arnold, Lorenza Bordoli, Jürgen Kopp, Torsten Schwede | Bioinformatics | 2006 | 16301204 | Yes |
2420 | 1349 | 1349.0 | 41.1 | 41.1 | Neurotransmitters and neuromodulators in the basal ganglia. | A M Graybiel | Trends Neurosci | 1990 | 1695398 | No |
2421 | 5395 | 1348.8 | 124.54 | 31.1 | Quantitative monitoring of gene expression patterns with a complementary DNA microarray. | M Schena, D Shalon, R W Davis, P O Brown | Science | 1995 | 7569999 | Yes |
2422 | 1348 | 1348.0 | 35.57 | 35.6 | Seminars in medicine of the Beth Israel Hospital, Boston. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies. | S L Friedman | N Engl J Med | 1993 | 8502273 | No |
2423 | 2696 | 1348.0 | 65.95 | 33.0 | The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. | Daniel J Drucker, Michael A Nauck | Lancet | 2006 | 17098089 | No |
2424 | 2696 | 1348.0 | 75.61 | 37.8 | Epidemiology of invasive candidiasis: a persistent public health problem. | M A Pfaller, D J Diekema | Clin Microbiol Rev | 2007 | 17223626 | No |
2425 | 2695 | 1347.5 | 64.97 | 32.5 | Regulation mechanisms and signaling pathways of autophagy. | Congcong He, Daniel J Klionsky | Annu Rev Genet | 2009 | 19653858 | No |
2426 | 1347 | 1347.0 | 33.74 | 33.7 | A molecular view of microbial diversity and the biosphere. | N R Pace | Science | 1997 | 9115194 | No |
2427 | 4040 | 1346.7 | 115.73 | 38.6 | A rapid bootstrap algorithm for the RAxML Web servers. | Alexandros Stamatakis, Paul Hoover, Jacques Rougemont | Syst Biol | 2008 | 18853362 | Yes |
2428 | 1346 | 1346.0 | 42.1 | 42.1 | Renin-angiotensin system: biochemistry and mechanisms of action. | M J Peach | Physiol Rev | 1977 | 191856 | No |
2429 | 1346 | 1346.0 | 28.09 | 28.1 | Stereological principles for morphometry in electron microscopic cytology. | E R Weibel | Int Rev Cytol | 1969 | 4899604 | No |
2430 | 1346 | 1346.0 | 26.05 | 26.1 | Chromosomal translocations in human cancer. | T H Rabbitts | Nature | 1994 | 7969446 | No |
2431 | 2692 | 1346.0 | 61.59 | 30.8 | The RXR heterodimers and orphan receptors. | D J Mangelsdorf, R M Evans | Cell | 1995 | 8521508 | No |
2432 | 1345 | 1345.0 | 28.59 | 28.6 | HIF-1: mediator of physiological and pathophysiological responses to hypoxia. | G L Semenza | J Appl Physiol (1985) | 2000 | 10749844 | No |
2433 | 2689 | 1344.5 | 75.54 | 37.8 | The OPLS [optimized potentials for liquid simulations] potential functions for proteins, energy minimizations for crystals of cyclic peptides and crambin. | W L Jorgensen, J Tirado-Rives | J Am Chem Soc | 1988 | 27557051 | Yes |
2434 | 2688 | 1344.0 | 90.17 | 45.1 | Plasma-high-density-lipoprotein concentration and development of ischaemic heart-disease. | G J Miller, N E Miller | Lancet | 1975 | 46338 | Yes |
2435 | 1344 | 1344.0 | 45.18 | 45.2 | Functional organization of central pathways regulating the cardiovascular system. | R A Dampney | Physiol Rev | 1994 | 8171117 | No |
2436 | 1344 | 1344.0 | 24.29 | 24.3 | c-Myc target genes involved in cell growth, apoptosis, and metabolism. | C V Dang | Mol Cell Biol | 1999 | 9858526 | No |
2437 | 1344 | 1344.0 | 0.0 | 0.0 | The critical incident technique. | J C Flanagan | Psychol Bull | 1954 | 13177800 | Yes |
2438 | 2688 | 1344.0 | 83.49 | 41.7 | CTFFIND4: Fast and accurate defocus estimation from electron micrographs. | Alexis Rohou, Nikolaus Grigorieff | J Struct Biol | 2015 | 26278980 | Yes |
2439 | 2686 | 1343.0 | 61.68 | 30.8 | Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma. | G Blobel, B Dobberstein | J Cell Biol | 1975 | 811671 | Yes |
2440 | 1343 | 1343.0 | 50.76 | 50.8 | Translating social ecological theory into guidelines for community health promotion. | D Stokols | Am J Health Promot | 1996 | 10159709 | No |
2441 | 2683 | 1341.5 | 77.83 | 38.9 | Evidence For The Existence Of Monoamine-Containing Neurons In The Central Nervous System. I. Demonstration Of Monoamines In The Cell Bodies Of Brain Stem Neurons. | A Dahlstroem, K Fuxe | Acta Physiol Scand Suppl | 1964 | 14229500 | Yes |
2442 | 9388 | 1341.1 | 380.97 | 54.4 | Development and validation of a geriatric depression screening scale: a preliminary report. | J A Yesavage, T L Brink, T L Rose, O Lum, V Huang, M Adey, V O Leirer | J Psychiatr Res | 1982 | 7183759 | Yes |
2443 | 1341 | 1341.0 | 39.01 | 39.0 | Osteoblast adhesion on biomaterials. | K Anselme | Biomaterials | 2000 | 10711964 | No |
2444 | 1341 | 1341.0 | 37.64 | 37.6 | Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles. | Felix Kratz | J Control Release | 2008 | 18582981 | No |
2445 | 1341 | 1341.0 | 43.02 | 43.0 | The amazing osteocyte. | Lynda F Bonewald | J Bone Miner Res | 2011 | 21254230 | No |
2446 | 1340 | 1340.0 | 35.62 | 35.6 | Fibronectin and its receptors. | E Ruoslahti | Annu Rev Biochem | 1988 | 2972252 | No |
2447 | 1340 | 1340.0 | 42.16 | 42.2 | The phenomenon of the acute phase response. | I Kushner | Ann N Y Acad Sci | 1982 | 7046585 | No |
2448 | 2680 | 1340.0 | 78.81 | 39.4 | A cognitive model of posttraumatic stress disorder. | A Ehlers, D M Clark | Behav Res Ther | 2000 | 10761279 | No |
2449 | 1340 | 1340.0 | 41.9 | 41.9 | Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data. | Thomas Heberer | Toxicol Lett | 2002 | 11988354 | Yes |
2450 | 1340 | 1340.0 | 27.37 | 27.4 | The many faces of macrophage activation. | David M Mosser | J Leukoc Biol | 2003 | 12554797 | No |
2451 | 1340 | 1340.0 | 0.0 | 0.0 | A simple ultraviolet spectrophotometric method for the determination of protein. | W J Waddell | J Lab Clin Med | 1956 | 13346201 | Yes |
2452 | 1339 | 1339.0 | 33.14 | 33.1 | The biologic clock: the mitochondria? | D Harman | J Am Geriatr Soc | 1972 | 5016631 | Yes |
2453 | 1339 | 1339.0 | 12.67 | 12.7 | Cellular resistance to infection. | G B Mackaness | J Exp Med | 1962 | 14467923 | Yes |
2454 | 1339 | 1339.0 | 25.16 | 25.2 | A modified procedure for lead staining of thin sections. | G Millonig | J Biophys Biochem Cytol | 1961 | 14474176 | Yes |
2455 | 1338 | 1338.0 | 47.85 | 47.9 | Letter: Grading of angina pectoris. | L Campeau | Circulation | 1976 | 947585 | Yes |
2456 | 1338 | 1338.0 | 29.25 | 29.2 | Physiological concentrations of purines and pyrimidines. | T W Traut | Mol Cell Biochem | 1994 | 7877593 | No |
2457 | 1338 | 1338.0 | 23.05 | 23.1 | Protein modification by SUMO. | Erica S Johnson | Annu Rev Biochem | 2004 | 15189146 | No |
2458 | 2675 | 1337.5 | 93.4 | 46.7 | Total energy intake: implications for epidemiologic analyses. | W Willett, M J Stampfer | Am J Epidemiol | 1986 | 3521261 | No |
2459 | 2675 | 1337.5 | 59.36 | 29.7 | ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking. | Matthew D Wilkerson, D Neil Hayes | Bioinformatics | 2010 | 20427518 | Yes |
2460 | 1337 | 1337.0 | 34.97 | 35.0 | The molten globule state as a clue for understanding the folding and cooperativity of globular-protein structure. | K Kuwajima | Proteins | 1989 | 2695928 | No |
2461 | 1337 | 1337.0 | 47.24 | 47.2 | Neuropeptide Y: complete amino acid sequence of the brain peptide. | K Tatemoto | Proc Natl Acad Sci U S A | 1982 | 6957876 | Yes |
2462 | 1337 | 1337.0 | 29.37 | 29.4 | Transcriptional control of adipocyte formation. | Stephen R Farmer | Cell Metab | 2006 | 17011499 | No |
2463 | 4011 | 1337.0 | 210.77 | 70.3 | Shedding light on the cell biology of extracellular vesicles. | Guillaume van Niel, Gisela D'Angelo, Graça Raposo | Nat Rev Mol Cell Biol | 2018 | 29339798 | No |
2464 | 2673 | 1336.5 | 87.34 | 43.7 | Origins and evolution of antibiotic resistance. | Julian Davies, Dorothy Davies | Microbiol Mol Biol Rev | 2010 | 20805405 | No |
2465 | 1336 | 1336.0 | 28.5 | 28.5 | The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. | G B Morin | Cell | 1989 | 2805070 | Yes |
2466 | 2671 | 1335.5 | 59.72 | 29.9 | A comparison of bayesian methods for haplotype reconstruction from population genotype data. | Matthew Stephens, Peter Donnelly | Am J Hum Genet | 2003 | 14574645 | Yes |
2467 | 2669 | 1334.5 | 54.28 | 27.1 | Regulated portals of entry into the cell. | Sean D Conner, Sandra L Schmid | Nature | 2003 | 12621426 | No |
2468 | 1334 | 1334.0 | 28.62 | 28.6 | Codon usage and tRNA content in unicellular and multicellular organisms. | T Ikemura | Mol Biol Evol | 1985 | 3916708 | No |
2469 | 1334 | 1334.0 | 29.78 | 29.8 | Physiological and molecular basis of thyroid hormone action. | P M Yen | Physiol Rev | 2001 | 11427693 | No |
2470 | 1334 | 1334.0 | 25.71 | 25.7 | microRNAs: tiny regulators with great potential. | V Ambros | Cell | 2001 | 11779458 | No |
2471 | 1334 | 1334.0 | 41.98 | 42.0 | Electrocatalyst approaches and challenges for automotive fuel cells. | Mark K Debe | Nature | 2012 | 22678278 | Yes |
2472 | 2667 | 1333.5 | 73.27 | 36.6 | Further improvements in the plaque technique for detecting single antibody-forming cells. | A J Cunningham, A Szenberg | Immunology | 1968 | 5653817 | Yes |
2473 | 1333 | 1333.0 | 20.69 | 20.7 | A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon. | A M Olovnikov | J Theor Biol | 1973 | 4754905 | Yes |
2474 | 1332 | 1332.0 | 35.81 | 35.8 | Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects. | E B Hunziker | Osteoarthritis Cartilage | 2002 | 12056848 | No |
2475 | 1330 | 1330.0 | 34.64 | 34.6 | The aryl hydrocarbon receptor complex. | O Hankinson | Annu Rev Pharmacol Toxicol | 1995 | 7598497 | No |
2476 | 1330 | 1330.0 | 39.35 | 39.4 | Circuitry and functional aspects of the insular lobe in primates including humans. | J R Augustine | Brain Res Brain Res Rev | 1996 | 8957561 | No |
2477 | 1330 | 1330.0 | 25.68 | 25.7 | Mechanisms of caspase activation and inhibition during apoptosis. | Yigong Shi | Mol Cell | 2002 | 11931755 | No |
2478 | 1329 | 1329.0 | 31.5 | 31.5 | Recent advances in neuroblastoma. | John M Maris | N Engl J Med | 2010 | 20558371 | No |
2479 | 1329 | 1329.0 | 59.38 | 59.4 | Machine Learning in Medicine. | Rahul C Deo | Circulation | 2015 | 26572668 | No |
2480 | 5315 | 1328.8 | 130.69 | 32.7 | Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. | D W Cleveland, S G Fischer, M W Kirschner, U K Laemmli | J Biol Chem | 1977 | 320200 | Yes |
2481 | 1328 | 1328.0 | 37.98 | 38.0 | Cytokinesis-block micronucleus cytome assay. | Michael Fenech | Nat Protoc | 2007 | 17546000 | Yes |
2482 | 1327 | 1327.0 | 33.69 | 33.7 | Thioredoxin and glutaredoxin systems. | A Holmgren | J Biol Chem | 1989 | 2668278 | No |
2483 | 6635 | 1327.0 | 182.13 | 36.4 | Transection of the oesophagus for bleeding oesophageal varices. | R N Pugh, I M Murray-Lyon, J L Dawson, M C Pietroni, R Williams | Br J Surg | 1973 | 4541913 | Yes |
2484 | 2654 | 1327.0 | 60.38 | 30.2 | Integrins and signal transduction pathways: the road taken. | E A Clark, J S Brugge | Science | 1995 | 7716514 | No |
2485 | 1327 | 1327.0 | 32.86 | 32.9 | N-heterocyclic carbenes: a new concept in organometallic catalysis. | Wolfgang A Herrmann | Angew Chem Int Ed Engl | 2002 | 19750753 | Yes |
2486 | 3980 | 1326.7 | 97.53 | 32.5 | Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm. | Y Zhang, M Brady, S Smith | IEEE Trans Med Imaging | 2001 | 11293691 | Yes |
2487 | 2652 | 1326.0 | 72.46 | 36.2 | A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival. | B G Durie, S E Salmon | Cancer | 1975 | 1182674 | Yes |
2488 | 1326 | 1326.0 | 23.08 | 23.1 | Regulatory T cells: key controllers of immunologic self-tolerance. | S Sakaguchi | Cell | 2000 | 10850488 | No |
2489 | 2651 | 1325.5 | 54.46 | 27.2 | Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter. | P J Southern, P Berg | J Mol Appl Genet | 1982 | 6286831 | Yes |
2490 | 2651 | 1325.5 | 67.17 | 33.6 | Therapeutic potential of resveratrol: the in vivo evidence. | Joseph A Baur, David A Sinclair | Nat Rev Drug Discov | 2006 | 16732220 | No |
2491 | 1325 | 1325.0 | 31.75 | 31.8 | Apoptosis in cancer therapy: crossing the threshold. | D E Fisher | Cell | 1994 | 8069905 | No |
2492 | 1325 | 1325.0 | 29.93 | 29.9 | Functions of the neurotrophins during nervous system development: what the knockouts are teaching us. | W D Snider | Cell | 1994 | 8205613 | No |
2493 | 1324 | 1324.0 | 29.14 | 29.1 | Measuring information transfer | T Schreiber | Phys Rev Lett | 2000 | 10991308 | Yes |
2494 | 1324 | 1324.0 | 28.07 | 28.1 | The enzymes, regulation, and genetics of bile acid synthesis. | David W Russell | Annu Rev Biochem | 2003 | 12543708 | No |
2495 | 1324 | 1324.0 | 23.38 | 23.4 | SUMO: a history of modification. | Ronald T Hay | Mol Cell | 2005 | 15808504 | No |
2496 | 1324 | 1324.0 | 33.95 | 34.0 | Microbial influences in inflammatory bowel diseases. | R Balfour Sartor | Gastroenterology | 2008 | 18242222 | No |
2497 | 1323 | 1323.0 | 65.47 | 65.5 | Displaced proximal humeral fractures. I. Classification and evaluation. | C S Neer | J Bone Joint Surg Am | 1970 | 5455339 | Yes |
2498 | 3968 | 1322.7 | 102.4 | 34.1 | Cognitive and emotional influences in anterior cingulate cortex. | G Bush, P Luu, M I Posner | Trends Cogn Sci | 2000 | 10827444 | Yes |
2499 | 1322 | 1322.0 | 24.61 | 24.6 | Antigen-specific interaction between T and B cells. | A Lanzavecchia | Nature | 1985 | 3157869 | Yes |
2500 | 1322 | 1322.0 | 50.86 | 50.9 | Free-radical mechanisms in tissue injury. | T F Slater | Biochem J | 1984 | 6383353 | No |
2501 | 1322 | 1322.0 | 23.1 | 23.1 | Clonal selection and learning in the antibody system. | K Rajewsky | Nature | 1996 | 8657279 | No |
2502 | 1322 | 1322.0 | 0.0 | 0.0 | On the psychophysical law. | S S Stevens | Psychol Rev | 1957 | 13441853 | Yes |
2503 | 1322 | 1322.0 | 37.93 | 37.9 | BEDTools: The Swiss-Army Tool for Genome Feature Analysis. | Aaron R Quinlan | Curr Protoc Bioinformatics | 2014 | 25199790 | Yes |
2504 | 3965 | 1321.7 | 90.25 | 30.1 | Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? | Witold Filipowicz, Suvendra N Bhattacharyya, Nahum Sonenberg | Nat Rev Genet | 2008 | 18197166 | No |
2505 | 3964 | 1321.3 | 99.13 | 33.0 | LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions. | A C Wallace, R A Laskowski, J M Thornton | Protein Eng | 1995 | 7630882 | Yes |
2506 | 2642 | 1321.0 | 55.5 | 27.8 | Liver regeneration. | G K Michalopoulos, M C DeFrances | Science | 1997 | 9082986 | No |
2507 | 5284 | 1321.0 | 116.94 | 29.2 | Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. | Eugenia E Calle, Carmen Rodriguez, Kimberly Walker-Thurmond, Michael J Thun | N Engl J Med | 2003 | 12711737 | Yes |
2508 | 2641 | 1320.5 | 64.14 | 32.1 | Microglia: active sensor and versatile effector cells in the normal and pathologic brain. | Uwe-Karsten Hanisch, Helmut Kettenmann | Nat Neurosci | 2007 | 17965659 | No |
2509 | 3961 | 1320.3 | 97.37 | 32.5 | The p53 tumour suppressor gene. | A J Levine, J Momand, C A Finlay | Nature | 1991 | 2046748 | No |
2510 | 2639 | 1319.5 | 90.54 | 45.3 | Functional interactions between the gut microbiota and host metabolism. | Valentina Tremaroli, Fredrik Bäckhed | Nature | 2012 | 22972297 | No |
2511 | 1319 | 1319.0 | 48.16 | 48.2 | The life and times of the Enterococcus. | B E Murray | Clin Microbiol Rev | 1990 | 2404568 | No |
2512 | 1319 | 1319.0 | 36.9 | 36.9 | Stimulus-secretion coupling: the concept and clues from chromaffin and other cells. | W W Douglas | Br J Pharmacol | 1968 | 4882190 | No |
2513 | 2638 | 1319.0 | 48.61 | 24.3 | Immunization of dissociated spleen cell cultures from normal mice. | R I Mishell, R W Dutton | J Exp Med | 1967 | 6034749 | Yes |
2514 | 1319 | 1319.0 | 63.41 | 63.4 | The clinical application of the biopsychosocial model. | G L Engel | Am J Psychiatry | 1980 | 7369396 | Yes |
2515 | 1319 | 1319.0 | 35.38 | 35.4 | Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. | Arnold I Caplan | J Cell Physiol | 2007 | 17620285 | No |
2516 | 3956 | 1318.7 | 106.86 | 35.6 | Nitric oxide and peroxynitrite in health and disease. | Pál Pacher, Joseph S Beckman, Lucas Liaudet | Physiol Rev | 2007 | 17237348 | No |
2517 | 5274 | 1318.5 | 132.63 | 33.2 | Universal sample preparation method for proteome analysis. | Jacek R Wiśniewski, Alexandre Zougman, Nagarjuna Nagaraj, Matthias Mann | Nat Methods | 2009 | 19377485 | Yes |
2518 | 3955 | 1318.3 | 84.11 | 28.0 | A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. | R Medzhitov, P Preston-Hurlburt, C A Janeway | Nature | 1997 | 9237759 | Yes |
2519 | 1318 | 1318.0 | 39.15 | 39.1 | Classification of chronic viral hepatitis: a need for reassessment. | P J Scheuer | J Hepatol | 1991 | 1808228 | No |
2520 | 2636 | 1318.0 | 96.71 | 48.4 | Enzyme-linked immunosorbent assay, Elisa. 3. Quantitation of specific antibodies by enzyme-labeled anti-immunoglobulin in antigen-coated tubes. | E Engvall, P Perlmann | J Immunol | 1972 | 4113792 | Yes |
2521 | 1318 | 1318.0 | 51.34 | 51.3 | What is self-rated health and why does it predict mortality? Towards a unified conceptual model. | Marja Jylhä | Soc Sci Med | 2009 | 19520474 | Yes |
2522 | 3950 | 1316.7 | 147.84 | 49.3 | Complex heatmaps reveal patterns and correlations in multidimensional genomic data. | Zuguang Gu, Roland Eils, Matthias Schlesner | Bioinformatics | 2016 | 27207943 | Yes |
2523 | 1316 | 1316.0 | 36.98 | 37.0 | The matrix-degrading metalloproteinases. | L M Matrisian | Bioessays | 1992 | 1445287 | No |
2524 | 1316 | 1316.0 | 45.17 | 45.2 | Carnitine--metabolism and functions. | J Bremer | Physiol Rev | 1983 | 6361812 | No |
2525 | 1316 | 1316.0 | 0.0 | 0.0 | A quantitative immunochemical measure of the primary interaction between I BSA and antibody. | R S Farr | J Infect Dis | 1958 | 13611294 | Yes |
2526 | 1316 | 1316.0 | 118.79 | 118.8 | Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults. | Jonas F Ludvigsson | Acta Paediatr | 2020 | 32202343 | Yes |
2527 | 1315 | 1315.0 | 34.61 | 34.6 | Phylogenies from molecular sequences: inference and reliability. | J Felsenstein | Annu Rev Genet | 1988 | 3071258 | No |
2528 | 1315 | 1315.0 | 17.04 | 17.0 | Disconnexion syndromes in animals and man. I. | N Geschwind | Brain | 1965 | 5318481 | No |
2529 | 1315 | 1315.0 | 42.57 | 42.6 | An application of prefrontal cortex function theory to cognitive aging. | R L West | Psychol Bull | 1996 | 8831298 | No |
2530 | 1315 | 1315.0 | 28.22 | 28.2 | Prediction of protein cellular attributes using pseudo-amino acid composition. | K C Chou | Proteins | 2001 | 11288174 | Yes |
2531 | 1315 | 1315.0 | 28.5 | 28.5 | Mechanisms of foxp3+ T regulatory cell-mediated suppression. | Ethan M Shevach | Immunity | 2009 | 19464986 | No |
2532 | 2628 | 1314.0 | 41.45 | 20.7 | Functions of lysosomes. | C De Duve, R Wattiaux | Annu Rev Physiol | 1966 | 5322983 | No |
2533 | 1314 | 1314.0 | 27.65 | 27.6 | Double identity for proteins of the Bcl-2 family. | J C Reed | Nature | 1997 | 9194558 | No |
2534 | 1314 | 1314.0 | 33.25 | 33.2 | Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders. | R M Sapolsky | Arch Gen Psychiatry | 2000 | 11015810 | No |
2535 | 1314 | 1314.0 | 26.93 | 26.9 | Solving structures of protein complexes by molecular replacement with Phaser. | Airlie J McCoy | Acta Crystallogr D Biol Crystallogr | 2007 | 17164524 | Yes |
2536 | 2627 | 1313.5 | 100.6 | 50.3 | Malondialdehyde determination as index of lipid peroxidation. | H H Draper, M Hadley | Methods Enzymol | 1990 | 2233309 | Yes |
2537 | 2627 | 1313.5 | 58.15 | 29.1 | Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. | Jane E Visvader, Geoffrey J Lindeman | Nat Rev Cancer | 2008 | 18784658 | No |
2538 | 2626 | 1313.0 | 48.84 | 24.4 | New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. | R D Gietz, A Sugino | Gene | 1988 | 3073106 | Yes |
2539 | 2626 | 1313.0 | 46.62 | 23.3 | Rab proteins as membrane organizers. | M Zerial, H McBride | Nat Rev Mol Cell Biol | 2001 | 11252952 | No |
2540 | 1312 | 1312.0 | 32.81 | 32.8 | Comparative physiology of salt and water stress. | R. Munns | Plant Cell Environ | 2002 | 11841667 | Yes |
2541 | 1312 | 1312.0 | 32.58 | 32.6 | Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. | G L Semenza | Oncogene | 2010 | 19946328 | No |
2542 | 1312 | 1312.0 | 57.9 | 57.9 | 1,500 scientists lift the lid on reproducibility. | Monya Baker | Nature | 2016 | 27225100 | No |
2543 | 5246 | 1311.5 | 123.76 | 30.9 | Improved prediction of signal peptides: SignalP 3.0. | Jannick Dyrløv Bendtsen, Henrik Nielsen, Gunnar von Heijne, Søren Brunak | J Mol Biol | 2004 | 15223320 | Yes |
2544 | 2623 | 1311.5 | 61.31 | 30.7 | Microenvironmental regulation of metastasis. | Johanna A Joyce, Jeffrey W Pollard | Nat Rev Cancer | 2009 | 19279573 | No |
2545 | 2620 | 1310.0 | 117.12 | 58.6 | Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty. | J M Tanner, R H Whitehouse | Arch Dis Child | 1976 | 952550 | Yes |
2546 | 1310 | 1310.0 | 0.0 | 0.0 | Analyzer for accurate estimation of respiratory gases in one-half cubic centimeter samples. | P F Scholander | J Biol Chem | 1947 | 20281644 | Yes |
2547 | 2620 | 1310.0 | 71.33 | 35.7 | Tumor metastasis: molecular insights and evolving paradigms. | Scott Valastyan, Robert A Weinberg | Cell | 2011 | 22000009 | No |
2548 | 6548 | 1309.6 | 251.78 | 50.4 | Fsl. | Mark Jenkinson, Christian F Beckmann, Timothy E J Behrens, Mark W Woolrich, Stephen M Smith | Neuroimage | 2012 | 21979382 | No |
2549 | 2619 | 1309.5 | 59.32 | 29.7 | Supercoil sequencing: a fast and simple method for sequencing plasmid DNA. | E Y Chen, P H Seeburg | DNA | 1985 | 3996185 | Yes |
2550 | 3927 | 1309.0 | 139.61 | 46.5 | A new method for off-line removal of ocular artifact. | G Gratton, M G Coles, E Donchin | Electroencephalogr Clin Neurophysiol | 1983 | 6187540 | Yes |
2551 | 1309 | 1309.0 | 33.89 | 33.9 | Supported membranes: scientific and practical applications. | E Sackmann | Science | 1996 | 8539599 | No |
2552 | 1309 | 1309.0 | 0.0 | 0.0 | The anterior approach for removal of ruptured cervical disks. | R B Cloward | J Neurosurg | 1958 | 13599052 | Yes |
2553 | 1309 | 1309.0 | 27.47 | 27.5 | Human natural killer cells. | Michael A Caligiuri | Blood | 2008 | 18650461 | No |
2554 | 1307 | 1307.0 | 38.85 | 38.9 | Gadolinium--a specific trigger for the development of nephrogenic fibrosing dermopathy and nephrogenic systemic fibrosis? | Thomas Grobner | Nephrol Dial Transplant | 2006 | 16431890 | Yes |
2555 | 2613 | 1306.5 | 95.18 | 47.6 | Role of the microbiota in immunity and inflammation. | Yasmine Belkaid, Timothy W Hand | Cell | 2014 | 24679531 | No |
2556 | 3919 | 1306.3 | 93.13 | 31.0 | Functional porous coordination polymers. | Susumu Kitagawa, Ryo Kitaura, Shin-ichiro Noro | Angew Chem Int Ed Engl | 2004 | 15114565 | Yes |
2557 | 1306 | 1306.0 | 69.97 | 70.0 | Psychosocial resilience and protective mechanisms. | Michael Rutter | Am J Orthopsychiatry | 1987 | 3303954 | No |
2558 | 1306 | 1306.0 | 54.19 | 54.2 | Error in medicine. | L L Leape | JAMA | 1994 | 7503827 | Yes |
2559 | 1306 | 1306.0 | 34.75 | 34.8 | Sarcopenia: origins and clinical relevance. | I H Rosenberg | J Nutr | 1997 | 9164280 | No |
2560 | 1306 | 1306.0 | 35.28 | 35.3 | Polycystic ovary syndrome. | David A Ehrmann | N Engl J Med | 2005 | 15788499 | No |
2561 | 1306 | 1306.0 | 44.27 | 44.3 | AmpC beta-lactamases. | George A Jacoby | Clin Microbiol Rev | 2009 | 19136439 | No |
2562 | 2612 | 1306.0 | 105.9 | 53.0 | A typology of reviews: an analysis of 14 review types and associated methodologies. | Maria J Grant, Andrew Booth | Health Info Libr J | 2009 | 19490148 | No |
2563 | 2612 | 1306.0 | 63.35 | 31.7 | Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. | Subhra K Biswas, Alberto Mantovani | Nat Immunol | 2010 | 20856220 | No |
2564 | 2612 | 1306.0 | 190.37 | 95.2 | ape 5.0: an environment for modern phylogenetics and evolutionary analyses in R. | Emmanuel Paradis, Klaus Schliep | Bioinformatics | 2019 | 30016406 | Yes |
2565 | 2610 | 1305.0 | 40.31 | 20.2 | The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites. | J Shine, L Dalgarno | Proc Natl Acad Sci U S A | 1974 | 4598299 | Yes |
2566 | 1305 | 1305.0 | 23.64 | 23.6 | CD95's deadly mission in the immune system. | P H Krammer | Nature | 2000 | 11048730 | No |
2567 | 1305 | 1305.0 | 29.72 | 29.7 | Metastatic bone disease: clinical features, pathophysiology and treatment strategies. | R E Coleman | Cancer Treat Rev | 2001 | 11417967 | No |
2568 | 1305 | 1305.0 | 30.99 | 31.0 | Non-Smad pathways in TGF-beta signaling. | Ying E Zhang | Cell Res | 2009 | 19114990 | No |
2569 | 2608 | 1304.0 | 86.99 | 43.5 | Social conditions as fundamental causes of disease. | B G Link, J Phelan | J Health Soc Behav | 1995 | 7560851 | No |
2570 | 2607 | 1303.5 | 56.12 | 28.1 | Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information. | M Zuker, P Stiegler | Nucleic Acids Res | 1981 | 6163133 | Yes |
2571 | 1303 | 1303.0 | 38.03 | 38.0 | Qinghaosu (artemisinin): an antimalarial drug from China. | D L Klayman | Science | 1985 | 3887571 | No |
2572 | 2606 | 1303.0 | 67.1 | 33.5 | Apoptosis, oncosis, and necrosis. An overview of cell death. | G Majno, I Joris | Am J Pathol | 1995 | 7856735 | No |
2573 | 3909 | 1303.0 | 80.4 | 26.8 | Calcium signalling: dynamics, homeostasis and remodelling. | Michael J Berridge, Martin D Bootman, H Llewelyn Roderick | Nat Rev Mol Cell Biol | 2003 | 12838335 | No |
2574 | 1303 | 1303.0 | 29.82 | 29.8 | Oxidative stress in neurodegeneration: cause or consequence? | Julie K Andersen | Nat Med | 2004 | 15298006 | No |
2575 | 1302 | 1302.0 | 31.18 | 31.2 | Receptors for epidermal growth factor and other polypeptide mitogens. | G Carpenter | Annu Rev Biochem | 1987 | 3039909 | No |
2576 | 1302 | 1302.0 | 44.58 | 44.6 | The theoretical bases of indirect calorimetry: a review. | E Ferrannini | Metabolism | 1988 | 3278194 | No |
2577 | 1302 | 1302.0 | 21.65 | 21.6 | Extraordinary sex ratios. A sex-ratio theory for sex linkage and inbreeding has new implications in cytogenetics and entomology. | W D Hamilton | Science | 1967 | 6021675 | Yes |
2578 | 2603 | 1301.5 | 43.63 | 21.8 | Genetic transformation of Drosophila with transposable element vectors. | G M Rubin, A C Spradling | Science | 1982 | 6289436 | Yes |
2579 | 1301 | 1301.0 | 34.2 | 34.2 | The sympathetic control of blood pressure. | Patrice G Guyenet | Nat Rev Neurosci | 2006 | 16760914 | No |
2580 | 3902 | 1300.7 | 90.57 | 30.2 | Tissue cells feel and respond to the stiffness of their substrate. | Dennis E Discher, Paul Janmey, Yu-Li Wang | Science | 2005 | 16293750 | No |
2581 | 2601 | 1300.5 | 82.65 | 41.3 | Epidermal growth factor. | G Carpenter, S Cohen | Annu Rev Biochem | 1979 | 382984 | No |
2582 | 3901 | 1300.3 | 85.91 | 28.6 | Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. | Axel Nimmerjahn, Frank Kirchhoff, Fritjof Helmchen | Science | 2005 | 15831717 | Yes |
2583 | 1299 | 1299.0 | 42.34 | 42.3 | Optimal foraging, the marginal value theorem. | E L Charnov | Theor Popul Biol | 1976 | 1273796 | Yes |
2584 | 7785 | 1297.5 | 197.0 | 32.8 | Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research. | Ana Conesa, Stefan Götz, Juan Miguel García-Gómez, Javier Terol, Manuel Talón, Montserrat Robles | Bioinformatics | 2005 | 16081474 | Yes |
2585 | 1297 | 1297.0 | 28.46 | 28.5 | Long-term potentiation and memory. | M A Lynch | Physiol Rev | 2004 | 14715912 | No |
2586 | 1297 | 1297.0 | 60.02 | 60.0 | Oxidative stress: a concept in redox biology and medicine. | Helmut Sies | Redox Biol | 2015 | 25588755 | No |
2587 | 2593 | 1296.5 | 82.73 | 41.4 | Tumor-associated macrophages: from mechanisms to therapy. | Roy Noy, Jeffrey W Pollard | Immunity | 2014 | 25035953 | No |
2588 | 1296 | 1296.0 | 43.67 | 43.7 | Ruthenium red and violet. I. Chemistry, purification, methods of use for electron microscopy and mechanism of action. | J H Luft | Anat Rec | 1971 | 4108333 | Yes |
2589 | 1296 | 1296.0 | 11.62 | 11.6 | Metabolic stability and epigenesis in randomly constructed genetic nets. | S A Kauffman | J Theor Biol | 1969 | 5803332 | Yes |
2590 | 1296 | 1296.0 | 29.86 | 29.9 | The path to ubiquitous and low-cost organic electronic appliances on plastic. | Stephen R Forrest | Nature | 2004 | 15118718 | Yes |
2591 | 2591 | 1295.5 | 55.76 | 27.9 | Mitochondrial control of cell death. | G Kroemer, J C Reed | Nat Med | 2000 | 10802706 | No |
2592 | 2591 | 1295.5 | 59.06 | 29.5 | Cell cycle, CDKs and cancer: a changing paradigm. | Marcos Malumbres, Mariano Barbacid | Nat Rev Cancer | 2009 | 19238148 | No |
2593 | 5181 | 1295.2 | 103.79 | 25.9 | Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. | D D Sarbassov, David A Guertin, Siraj M Ali, David M Sabatini | Science | 2005 | 15718470 | Yes |
2594 | 6470 | 1294.0 | 159.15 | 31.8 | Enzymatic determination of total serum cholesterol. | C C Allain, L S Poon, C S Chan, W Richmond, P C Fu | Clin Chem | 1974 | 4818200 | Yes |
2595 | 3882 | 1294.0 | 99.46 | 33.2 | Atomic force microscope. | G Binnig, C F Quate, C Gerber | Phys Rev Lett | 1986 | 10033323 | Yes |
2596 | 1294 | 1294.0 | 0.0 | 0.0 | Limitations of the application of fourfold table analysis to hospital data. | J Berkson | Biometrics | 1946 | 21001024 | Yes |
2597 | 2587 | 1293.5 | 37.83 | 18.9 | Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. | J E Sulston, H R Horvitz | Dev Biol | 1977 | 838129 | Yes |
2598 | 2586 | 1293.0 | 61.5 | 30.8 | Multipoint quantitative-trait linkage analysis in general pedigrees. | L Almasy, J Blangero | Am J Hum Genet | 1998 | 9545414 | Yes |
2599 | 1292 | 1292.0 | 31.73 | 31.7 | Surrogate endpoints in clinical trials: definition and operational criteria. | R L Prentice | Stat Med | 1989 | 2727467 | Yes |
2600 | 1292 | 1292.0 | 39.49 | 39.5 | Chronic disease management: what will it take to improve care for chronic illness? | E H Wagner | Eff Clin Pract | 1998 | 10345255 | No |
2601 | 1292 | 1292.0 | 0.0 | 0.0 | On the local reactions of the arterial wall to changes of internal pressure. | W M Bayliss | J Physiol | 1902 | 16992618 | Yes |
2602 | 1292 | 1292.0 | 29.78 | 29.8 | Tumour necrosis factor and cancer. | Frances Balkwill | Nat Rev Cancer | 2009 | 19343034 | No |
2603 | 2582 | 1291.0 | 75.2 | 37.6 | Prediction of the secondary structure of proteins from their amino acid sequence. | P Y Chou, G D Fasman | Adv Enzymol Relat Areas Mol Biol | 1978 | 364941 | No |
2604 | 1291 | 1291.0 | 30.11 | 30.1 | Pathways of oxidative damage. | James A Imlay | Annu Rev Microbiol | 2003 | 14527285 | No |
2605 | 3872 | 1290.7 | 100.98 | 33.7 | Bacterial biofilms: from the natural environment to infectious diseases. | Luanne Hall-Stoodley, J William Costerton, Paul Stoodley | Nat Rev Microbiol | 2004 | 15040259 | No |
2606 | 6453 | 1290.6 | 121.69 | 24.3 | Crystal structure of the nucleosome core particle at 2.8 A resolution. | K Luger, A W Mäder, R K Richmond, D F Sargent, T J Richmond | Nature | 1997 | 9305837 | Yes |
2607 | 5161 | 1290.2 | 224.47 | 56.1 | Progressive statistics for studies in sports medicine and exercise science. | William G Hopkins, Stephen W Marshall, Alan M Batterham, Juri Hanin | Med Sci Sports Exerc | 2009 | 19092709 | No |
2608 | 1290 | 1290.0 | 29.51 | 29.5 | Oxyradicals and DNA damage. | L J Marnett | Carcinogenesis | 2000 | 10688856 | No |
2609 | 2579 | 1289.5 | 61.19 | 30.6 | Production of single-stranded plasmid DNA. | J Vieira, J Messing | Methods Enzymol | 1987 | 3323803 | Yes |
2610 | 1289 | 1289.0 | 30.44 | 30.4 | Lymphokine production by human T cells in disease states. | S Romagnani | Annu Rev Immunol | 1994 | 8011282 | No |
2611 | 1289 | 1289.0 | 37.91 | 37.9 | Endometriosis. | Serdar E Bulun | N Engl J Med | 2009 | 19144942 | No |
2612 | 3866 | 1288.7 | 91.06 | 30.4 | Evolution and functions of long noncoding RNAs. | Chris P Ponting, Peter L Oliver, Wolf Reik | Cell | 2009 | 19239885 | No |
2613 | 1288 | 1288.0 | 33.12 | 33.1 | Psychological and neural mechanisms of the affective dimension of pain. | D D Price | Science | 2000 | 10846154 | No |
2614 | 1288 | 1288.0 | 29.11 | 29.1 | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. | Nigel Unwin | J Mol Biol | 2005 | 15701510 | Yes |
2615 | 2575 | 1287.5 | 61.67 | 30.8 | C-reactive protein: a critical update. | Mark B Pepys, Gideon M Hirschfield | J Clin Invest | 2003 | 12813013 | No |
2616 | 2575 | 1287.5 | 56.69 | 28.3 | Breaking the diffraction resolution limit by stimulated emission: stimulated-emission-depletion fluorescence microscopy. | S W Hell, J Wichmann | Opt Lett | 1994 | 19844443 | Yes |
2617 | 1287 | 1287.0 | 33.7 | 33.7 | Isolation of leucocytes from human blood. Further observations. Methylcellulose, dextran, and ficoll as erythrocyteaggregating agents. | A Böyum | Scand J Clin Lab Invest Suppl | 1968 | 4179066 | Yes |
2618 | 2574 | 1287.0 | 71.01 | 35.5 | What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience? | K C Berridge, T E Robinson | Brain Res Brain Res Rev | 1998 | 9858756 | No |
2619 | 1287 | 1287.0 | 55.13 | 55.1 | Rhythms for Cognition: Communication through Coherence. | Pascal Fries | Neuron | 2015 | 26447583 | No |
2620 | 2573 | 1286.5 | 87.64 | 43.8 | Regulatory sequences involved in the promotion and termination of RNA transcription. | M Rosenberg, D Court | Annu Rev Genet | 1979 | 94251 | No |
2621 | 1286 | 1286.0 | 39.62 | 39.6 | Electrophoretic separation of plasma lipoproteins in agarose gel. | R P Noble | J Lipid Res | 1968 | 4176473 | Yes |
2622 | 1286 | 1286.0 | 59.33 | 59.3 | Cardiovascular and renal actions of dopamine: potential clinical applications. | L I Goldberg | Pharmacol Rev | 1972 | 4554480 | No |
2623 | 1286 | 1286.0 | 35.14 | 35.1 | The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions. | R G Gerrity | Am J Pathol | 1981 | 7234961 | Yes |
2624 | 2572 | 1286.0 | 81.9 | 41.0 | Oxidative mechanisms in the toxicity of metal ions. | S J Stohs, D Bagchi | Free Radic Biol Med | 1995 | 7744317 | No |
2625 | 1286 | 1286.0 | 27.16 | 27.2 | The stem-cell niche as an entity of action. | David T Scadden | Nature | 2006 | 16810242 | No |
2626 | 1286 | 1286.0 | 40.46 | 40.5 | Thermal properties of graphene and nanostructured carbon materials. | Alexander A Balandin | Nat Mater | 2011 | 21778997 | Yes |
2627 | 2570 | 1285.0 | 65.31 | 32.7 | Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. | J A Ledbetter, L A Herzenberg | Immunol Rev | 1979 | 398327 | No |
2628 | 1285 | 1285.0 | 38.89 | 38.9 | Diversity and ubiquity of K channels. | B Rudy | Neuroscience | 1988 | 2457185 | No |
2629 | 1285 | 1285.0 | 30.68 | 30.7 | Papillomavirus infections--a major cause of human cancers. | H zur Hausen | Biochim Biophys Acta | 1996 | 8876633 | No |
2630 | 1284 | 1284.0 | 29.12 | 29.1 | Chemistry and biology of the immunophilins and their immunosuppressive ligands. | S L Schreiber | Science | 1991 | 1702904 | No |
2631 | 2568 | 1284.0 | 158.82 | 79.4 | Facial nerve grading system. | J W House, D E Brackmann | Otolaryngol Head Neck Surg | 1985 | 3921901 | Yes |
2632 | 2568 | 1284.0 | 63.76 | 31.9 | Interneurons of the hippocampus. | T F Freund, G Buzsáki | Hippocampus | 1996 | 8915675 | No |
2633 | 1284 | 1284.0 | 28.4 | 28.4 | Liver fibrosis -- from bench to bedside. | Scott L Friedman | J Hepatol | 2003 | 12591185 | No |
2634 | 2566 | 1283.0 | 0.0 | 0.0 | Primary carcinoma of the liver: a study of 100 cases among 48,900 necropsies. | H A Edmondson, P E Steiner | Cancer | 1954 | 13160935 | Yes |
2635 | 1283 | 1283.0 | 26.9 | 26.9 | Neuroligins and neurexins link synaptic function to cognitive disease. | Thomas C Südhof | Nature | 2008 | 18923512 | No |
2636 | 1283 | 1283.0 | 55.12 | 55.1 | Transcriptional architecture of the mammalian circadian clock. | Joseph S Takahashi | Nat Rev Genet | 2017 | 27990019 | No |
2637 | 2565 | 1282.5 | 46.73 | 23.4 | Live or let die: the cell's response to p53. | Karen H Vousden, Xin Lu | Nat Rev Cancer | 2002 | 12154352 | No |
2638 | 2565 | 1282.5 | 54.84 | 27.4 | The canonical Notch signaling pathway: unfolding the activation mechanism. | Raphael Kopan, Maria Xenia G Ilagan | Cell | 2009 | 19379690 | No |
2639 | 14103 | 1282.1 | 380.95 | 34.6 | The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. | Aram V Chobanian, George L Bakris, Henry R Black, William C Cushman, Lee A Green, Joseph L Izzo, Daniel W Jones, Barry J Materson, Suzanne Oparil, Jackson T Wright, Edward J Roccella | JAMA | 2003 | 12748199 | No |
2640 | 1282 | 1282.0 | 41.17 | 41.2 | How stigma interferes with mental health care. | Patrick Corrigan | Am Psychol | 2004 | 15491256 | Yes |
2641 | 1282 | 1282.0 | 32.58 | 32.6 | Pain and emotion interactions in subregions of the cingulate gyrus. | Brent A Vogt | Nat Rev Neurosci | 2005 | 15995724 | No |
2642 | 2563 | 1281.5 | 66.15 | 33.1 | Establishment and characterization of a human histiocytic lymphoma cell line (U-937). | C Sundström, K Nilsson | Int J Cancer | 1976 | 178611 | Yes |
2643 | 2563 | 1281.5 | 46.02 | 23.0 | DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. | Christopher J Bakkenist, Michael B Kastan | Nature | 2003 | 12556884 | Yes |
2644 | 1281 | 1281.0 | 80.1 | 80.1 | A comparison of canal preparations in straight and curved root canals. | S W Schneider | Oral Surg Oral Med Oral Pathol | 1971 | 5284110 | Yes |
2645 | 1281 | 1281.0 | 39.44 | 39.4 | Somatostatin. | S Reichlin | N Engl J Med | 1983 | 6139753 | No |
2646 | 2562 | 1281.0 | 129.03 | 64.5 | A study of the natural history of back pain. Part I: development of a reliable and sensitive measure of disability in low-back pain. | M Roland, R Morris | Spine (Phila Pa 1976) | 1983 | 6222486 | Yes |
2647 | 1281 | 1281.0 | 0.0 | 0.0 | Agammaglobulinemia. | O C Bruton | Pediatrics | 1952 | 14929630 | Yes |
2648 | 1281 | 1281.0 | 23.95 | 23.9 | Mobile elements: drivers of genome evolution. | Haig H Kazazian | Science | 2004 | 15016989 | No |
2649 | 3843 | 1281.0 | 127.2 | 42.4 | Rehospitalizations among patients in the Medicare fee-for-service program. | Stephen F Jencks, Mark V Williams, Eric A Coleman | N Engl J Med | 2009 | 19339721 | Yes |
2650 | 1280 | 1280.0 | 31.99 | 32.0 | The mitochondrial electron transport and oxidative phosphorylation system. | Y Hatefi | Annu Rev Biochem | 1985 | 2862839 | No |
2651 | 1280 | 1280.0 | 31.61 | 31.6 | Overview of general physiologic features and functions of vitamin D. | Hector F DeLuca | Am J Clin Nutr | 2004 | 15585789 | No |
2652 | 2559 | 1279.5 | 0.0 | 0.0 | Construct validity in psychological tests. | L J Cronbach, P E Meehl | Psychol Bull | 1955 | 13245896 | Yes |
2653 | 2559 | 1279.5 | 54.94 | 27.5 | The pathophysiology of mitochondrial cell death. | Douglas R Green, Guido Kroemer | Science | 2004 | 15286356 | No |
2654 | 1279 | 1279.0 | 46.67 | 46.7 | Substance P. | B Pernow | Pharmacol Rev | 1983 | 6196797 | No |
2655 | 1279 | 1279.0 | 28.48 | 28.5 | Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration. | T A Springer | Annu Rev Physiol | 1995 | 7778885 | No |
2656 | 1279 | 1279.0 | 44.83 | 44.8 | Plasma perspective on strong field multiphoton ionization. | P B Corkum | Phys Rev Lett | 1993 | 10054556 | Yes |
2657 | 1279 | 1279.0 | 41.42 | 41.4 | The epidemiology of adult obstructive sleep apnea. | Naresh M Punjabi | Proc Am Thorac Soc | 2008 | 18250205 | No |
2658 | 8952 | 1278.9 | 253.26 | 36.2 | Cancer statistics, 2008. | Ahmedin Jemal, Rebecca Siegel, Elizabeth Ward, Yongping Hao, Jiaquan Xu, Taylor Murray, Michael J Thun | CA Cancer J Clin | 2008 | 18287387 | Yes |
2659 | 3836 | 1278.7 | 86.7 | 28.9 | Photodynamic therapy for cancer. | Dennis E J G J Dolmans, Dai Fukumura, Rakesh K Jain | Nat Rev Cancer | 2003 | 12724736 | No |
2660 | 2557 | 1278.5 | 52.59 | 26.3 | The molecular biology of axon guidance. | M Tessier-Lavigne, C S Goodman | Science | 1996 | 8895455 | No |
2661 | 2557 | 1278.5 | 62.79 | 31.4 | The free radical theory of aging matures. | K B Beckman, B N Ames | Physiol Rev | 1998 | 9562038 | No |
2662 | 1278 | 1278.0 | 34.74 | 34.7 | Neural simulation of action: a unifying mechanism for motor cognition. | M Jeannerod | Neuroimage | 2001 | 11373140 | No |
2663 | 3832 | 1277.3 | 136.14 | 45.4 | Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. | Marina Colombo, Graça Raposo, Clotilde Théry | Annu Rev Cell Dev Biol | 2014 | 25288114 | No |
2664 | 1277 | 1277.0 | 55.92 | 55.9 | Biomaterial-centered infection: microbial adhesion versus tissue integration. | A G Gristina | Science | 1987 | 3629258 | Yes |
2665 | 1277 | 1277.0 | 40.95 | 41.0 | Bee and wasp venoms. | E Habermann | Science | 1972 | 4113805 | No |
2666 | 2554 | 1277.0 | 23.61 | 11.8 | Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. | J Altman, G D Das | J Comp Neurol | 1965 | 5861717 | Yes |
2667 | 1277 | 1277.0 | 26.9 | 26.9 | Recognition and processing of ubiquitin-protein conjugates by the proteasome. | Daniel Finley | Annu Rev Biochem | 2009 | 19489727 | No |
2668 | 1276 | 1276.0 | 22.43 | 22.4 | The molecular motor toolbox for intracellular transport. | Ronald D Vale | Cell | 2003 | 12600311 | No |
2669 | 2552 | 1276.0 | 80.54 | 40.3 | Molecular and cellular insights into T cell exhaustion. | E John Wherry, Makoto Kurachi | Nat Rev Immunol | 2015 | 26205583 | No |
2670 | 7655 | 1275.8 | 192.28 | 32.0 | An obesity-associated gut microbiome with increased capacity for energy harvest. | Peter J Turnbaugh, Ruth E Ley, Michael A Mahowald, Vincent Magrini, Elaine R Mardis, Jeffrey I Gordon | Nature | 2006 | 17183312 | Yes |
2671 | 2551 | 1275.5 | 73.6 | 36.8 | Alternatives for logistic regression in cross-sectional studies: an empirical comparison of models that directly estimate the prevalence ratio. | Aluísio J D Barros, Vânia N Hirakata | BMC Med Res Methodol | 2003 | 14567763 | Yes |
2672 | 1275 | 1275.0 | 60.86 | 60.9 | New norms of upper limb fat and muscle areas for assessment of nutritional status. | A R Frisancho | Am J Clin Nutr | 1981 | 6975564 | Yes |
2673 | 1275 | 1275.0 | 42.97 | 43.0 | Density matrix formulation for quantum renormalization groups. | S R White | Phys Rev Lett | 1992 | 10046608 | Yes |
2674 | 2550 | 1275.0 | 63.24 | 31.6 | Neuronal plasticity: increasing the gain in pain. | C J Woolf, M W Salter | Science | 2000 | 10846153 | No |
2675 | 1275 | 1275.0 | 0.0 | 0.0 | Differential spectrophotometry of purine compounds by means of specific enzymes; studies of the enzymes of purine metabolism. | H M Kalckar | J Biol Chem | 1947 | 20285041 | Yes |
2676 | 2549 | 1274.5 | 67.18 | 33.6 | Integrins in cancer: biological implications and therapeutic opportunities. | Jay S Desgrosellier, David A Cheresh | Nat Rev Cancer | 2010 | 20029421 | No |
2677 | 1274 | 1274.0 | 25.57 | 25.6 | Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy. | R H Schwartz | Cell | 1992 | 1335362 | No |
2678 | 1274 | 1274.0 | 42.42 | 42.4 | Phenylpropanoid biosynthesis. | Thomas Vogt | Mol Plant | 2010 | 20035037 | No |
2679 | 1274 | 1274.0 | 38.64 | 38.6 | Persister cells. | Kim Lewis | Annu Rev Microbiol | 2010 | 20528688 | No |
2680 | 2547 | 1273.5 | 58.76 | 29.4 | Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. | Kornelia Polyak, Robert A Weinberg | Nat Rev Cancer | 2009 | 19262571 | No |
2681 | 1273 | 1273.0 | 33.82 | 33.8 | The biochemistry and medical significance of the flavonoids. | Bent H Havsteen | Pharmacol Ther | 2002 | 12453566 | No |
2682 | 1273 | 1273.0 | 32.13 | 32.1 | Plasmonics: merging photonics and electronics at nanoscale dimensions. | Ekmel Ozbay | Science | 2006 | 16410515 | Yes |
2683 | 2545 | 1272.5 | 56.54 | 28.3 | The codon Adaptation Index--a measure of directional synonymous codon usage bias, and its potential applications. | P M Sharp, W H Li | Nucleic Acids Res | 1987 | 3547335 | Yes |
2684 | 2545 | 1272.5 | 59.42 | 29.7 | Quorum sensing in bacteria. | M B Miller, B L Bassler | Annu Rev Microbiol | 2001 | 11544353 | No |
2685 | 1272 | 1272.0 | 20.87 | 20.9 | Antigen receptor tail clue. | M Reth | Nature | 1989 | 2927501 | Yes |
2686 | 2544 | 1272.0 | 68.14 | 34.1 | Chlorophyll fluorescence--a practical guide. | K Maxwell, G N Johnson | J Exp Bot | 2000 | 10938857 | No |
2687 | 1272 | 1272.0 | 27.12 | 27.1 | Sustainable hydrogen production. | John A Turner | Science | 2004 | 15310892 | Yes |
2688 | 2544 | 1272.0 | 67.36 | 33.7 | Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. | Ajay Kumar Gupta, Mona Gupta | Biomaterials | 2005 | 15626447 | No |
2689 | 1272 | 1272.0 | 31.4 | 31.4 | Hydrogen sulphide and its therapeutic potential. | Csaba Szabó | Nat Rev Drug Discov | 2007 | 17948022 | No |
2690 | 1272 | 1272.0 | 36.82 | 36.8 | Species concepts and species delimitation. | Kevin De Queiroz | Syst Biol | 2007 | 18027281 | Yes |
2691 | 1272 | 1272.0 | 0.0 | 0.0 | The antidiuretic hormone and the factors which determine its release. | E B Verney | Proc R Soc Lond B Biol Sci | 1947 | 18918876 | Yes |
2692 | 1272 | 1272.0 | 117.32 | 117.3 | COVID-19 and African Americans. | Clyde W Yancy | JAMA | 2020 | 32293639 | Yes |
2693 | 2543 | 1271.5 | 50.62 | 25.3 | A rapid, sensitive, and specific method for the determination of protein in dilute solution. | W Schaffner, C Weissmann | Anal Biochem | 1973 | 4128882 | Yes |
2694 | 2543 | 1271.5 | 48.79 | 24.4 | Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis. | M Fried, D M Crothers | Nucleic Acids Res | 1981 | 6275366 | Yes |
2695 | 5086 | 1271.5 | 112.45 | 28.1 | A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes. | Vsevolod V Rostovtsev, Luke G Green, Valery V Fokin, K Barry Sharpless | Angew Chem Int Ed Engl | 2002 | 12203546 | Yes |
2696 | 1271 | 1271.0 | 29.26 | 29.3 | The prefrontal cortex and cognitive control. | E K Miller | Nat Rev Neurosci | 2000 | 11252769 | No |
2697 | 1271 | 1271.0 | 34.29 | 34.3 | How brains beware: neural mechanisms of emotional attention. | Patrik Vuilleumier | Trends Cogn Sci | 2005 | 16289871 | Yes |
2698 | 2542 | 1271.0 | 81.05 | 40.5 | DPARSF: A MATLAB Toolbox for "Pipeline" Data Analysis of Resting-State fMRI. | Yan Chao-Gan, Zang Yu-Feng | Front Syst Neurosci | 2010 | 20577591 | Yes |
2699 | 1270 | 1270.0 | 29.99 | 30.0 | Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. | Hiroshi Takayanagi | Nat Rev Immunol | 2007 | 17380158 | No |
2700 | 2540 | 1270.0 | 77.05 | 38.5 | Insights into the regulation of protein abundance from proteomic and transcriptomic analyses. | Christine Vogel, Edward M Marcotte | Nat Rev Genet | 2012 | 22411467 | No |
2701 | 2539 | 1269.5 | 84.54 | 42.3 | Surgical risk as related to time of intervention in the repair of intracranial aneurysms. | W E Hunt, R M Hess | J Neurosurg | 1968 | 5635959 | Yes |
2702 | 2538 | 1269.0 | 57.18 | 28.6 | Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. | D A Brown, J K Rose | Cell | 1992 | 1531449 | Yes |
2703 | 1269 | 1269.0 | 34.78 | 34.8 | Tumor angiogenesis. | J Folkman | Adv Cancer Res | 1985 | 2581424 | No |
2704 | 3807 | 1269.0 | 128.44 | 42.8 | Job burnout. | C Maslach, W B Schaufeli, M P Leiter | Annu Rev Psychol | 2001 | 11148311 | Yes |
2705 | 2537 | 1268.5 | 76.11 | 38.1 | An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. | Sun Ho Kim, Jin Mo Chung | Pain | 1992 | 1333581 | Yes |
2706 | 2537 | 1268.5 | 61.34 | 30.7 | Drug delivery systems: entering the mainstream. | Theresa M Allen, Pieter R Cullis | Science | 2004 | 15031496 | Yes |
2707 | 3801 | 1267.0 | 169.5 | 56.5 | In search of how people change. Applications to addictive behaviors. | J O Prochaska, C C DiClemente, J C Norcross | Am Psychol | 1992 | 1329589 | Yes |
2708 | 3801 | 1267.0 | 90.4 | 30.1 | Dystrophin: the protein product of the Duchenne muscular dystrophy locus. | E P Hoffman, R H Brown, L M Kunkel | Cell | 1987 | 3319190 | Yes |
2709 | 1267 | 1267.0 | 36.37 | 36.4 | A Wilcoxon-type test for trend. | J Cuzick | Stat Med | 1985 | 3992076 | Yes |
2710 | 1265 | 1265.0 | 30.47 | 30.5 | Short-term synaptic plasticity. | R S Zucker | Annu Rev Neurosci | 1989 | 2648947 | No |
2711 | 1265 | 1265.0 | 25.8 | 25.8 | Endocytosis and molecular sorting. | I Mellman | Annu Rev Cell Dev Biol | 1996 | 8970738 | No |
2712 | 1264 | 1264.0 | 24.79 | 24.8 | Structure and function of intercellular junctions. | L A Staehelin | Int Rev Cytol | 1974 | 4611943 | No |
2713 | 1264 | 1264.0 | 26.02 | 26.0 | Signal transduction via the MAP kinases: proceed at your own RSK. | J Blenis | Proc Natl Acad Sci U S A | 1993 | 8392180 | No |
2714 | 1264 | 1264.0 | 21.6 | 21.6 | Cancer susceptibility and the functions of BRCA1 and BRCA2. | Ashok R Venkitaraman | Cell | 2002 | 11832208 | No |
2715 | 2528 | 1264.0 | 9.57 | 4.8 | Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. | G J Todaro, H Green | J Cell Biol | 1963 | 13985244 | Yes |
2716 | 1264 | 1264.0 | 35.01 | 35.0 | Regulation of glutathione synthesis. | Shelly C Lu | Mol Aspects Med | 2009 | 18601945 | No |
2717 | 3791 | 1263.7 | 102.93 | 34.3 | Molecular characterization of a peripheral receptor for cannabinoids. | S Munro, K L Thomas, M Abu-Shaar | Nature | 1993 | 7689702 | Yes |
2718 | 1263 | 1263.0 | 31.53 | 31.5 | Apoptosis. | J J Cohen | Immunol Today | 1993 | 8466628 | No |
2719 | 1263 | 1263.0 | 62.31 | 62.3 | Biological roles of glycans. | Ajit Varki | Glycobiology | 2017 | 27558841 | No |
2720 | 2525 | 1262.5 | 48.93 | 24.5 | CpG islands in vertebrate genomes. | M Gardiner-Garden, M Frommer | J Mol Biol | 1987 | 3656447 | Yes |
2721 | 2525 | 1262.5 | 44.48 | 22.2 | The DNA damage response: putting checkpoints in perspective. | B B Zhou, S J Elledge | Nature | 2000 | 11100718 | No |
2722 | 1262 | 1262.0 | 32.14 | 32.1 | Rapid evolution of a protein in vitro by DNA shuffling. | W P Stemmer | Nature | 1994 | 8047147 | Yes |
2723 | 1262 | 1262.0 | 43.8 | 43.8 | PaDEL-descriptor: an open source software to calculate molecular descriptors and fingerprints. | Chun Wei Yap | J Comput Chem | 2011 | 21425294 | Yes |
2724 | 2523 | 1261.5 | 51.48 | 25.7 | Tumorigenesis and the angiogenic switch. | Gabriele Bergers, Laura E Benjamin | Nat Rev Cancer | 2003 | 12778130 | No |
2725 | 3784 | 1261.3 | 138.32 | 46.1 | Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. | C J Caspersen, K E Powell, G M Christenson | Public Health Rep | 1985 | 3920711 | Yes |
2726 | 1261 | 1261.0 | 14.14 | 14.1 | A restriction point for control of normal animal cell proliferation. | A B Pardee | Proc Natl Acad Sci U S A | 1974 | 4524638 | Yes |
2727 | 1261 | 1261.0 | 31.29 | 31.3 | Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution. | J Deisenhofer | Biochemistry | 1981 | 7236608 | Yes |
2728 | 1261 | 1261.0 | 25.8 | 25.8 | SETOR: hardware-lighted three-dimensional solid model representations of macromolecules. | S V Evans | J Mol Graph | 1993 | 8347566 | Yes |
2729 | 2522 | 1261.0 | 61.97 | 31.0 | Pharmacology and functions of metabotropic glutamate receptors. | P J Conn, J P Pin | Annu Rev Pharmacol Toxicol | 1997 | 9131252 | No |
2730 | 2522 | 1261.0 | 94.89 | 47.4 | Liposomal drug delivery systems: from concept to clinical applications. | Theresa M Allen, Pieter R Cullis | Adv Drug Deliv Rev | 2013 | 23036225 | No |
2731 | 5041 | 1260.2 | 184.27 | 46.1 | The chemistry and applications of metal-organic frameworks. | Hiroyasu Furukawa, Kyle E Cordova, Michael O'Keeffe, Omar M Yaghi | Science | 2013 | 23990564 | Yes |
2732 | 1260 | 1260.0 | 33.78 | 33.8 | Signaling through phosphatidylcholine breakdown. | J H Exton | J Biol Chem | 1990 | 2104616 | No |
2733 | 2520 | 1260.0 | 66.9 | 33.5 | Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction. | J L Weber, P E May | Am J Hum Genet | 1989 | 2916582 | Yes |
2734 | 1260 | 1260.0 | 25.23 | 25.2 | Searching for genetic determinants in the new millennium. | N J Risch | Nature | 2000 | 10866211 | No |
2735 | 2520 | 1260.0 | 56.22 | 28.1 | Can the pharmaceutical industry reduce attrition rates? | Ismail Kola, John Landis | Nat Rev Drug Discov | 2004 | 15286737 | No |
2736 | 1260 | 1260.0 | 31.59 | 31.6 | The effective period of preventive antibiotic action in experimental incisions and dermal lesions. | J F Burke | Surgery | 1961 | 16722001 | Yes |
2737 | 1259 | 1259.0 | 40.2 | 40.2 | Tumor delivery of macromolecular drugs based on the EPR effect. | Vladimir Torchilin | Adv Drug Deliv Rev | 2011 | 20304019 | No |
2738 | 1259 | 1259.0 | 36.29 | 36.3 | Deconvoluting the context-dependent role for autophagy in cancer. | Eileen White | Nat Rev Cancer | 2012 | 22534666 | No |
2739 | 2517 | 1258.5 | 78.11 | 39.1 | Modeling and comparison of dissolution profiles. | P Costa, J M Sousa Lobo | Eur J Pharm Sci | 2001 | 11297896 | No |
2740 | 2517 | 1258.5 | 68.77 | 34.4 | Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. | Taro Kawai, Shizuo Akira | Immunity | 2011 | 21616434 | No |
2741 | 1258 | 1258.0 | 27.8 | 27.8 | Life, death, and the pursuit of apoptosis. | E White | Genes Dev | 1996 | 8557188 | No |
2742 | 1258 | 1258.0 | 29.94 | 29.9 | Somatostatin and its receptor family. | Y C Patel | Front Neuroendocrinol | 1999 | 10433861 | No |
2743 | 3774 | 1258.0 | 89.97 | 30.0 | Thresholding of statistical maps in functional neuroimaging using the false discovery rate. | Christopher R Genovese, Nicole A Lazar, Thomas Nichols | Neuroimage | 2002 | 11906227 | Yes |
2744 | 1258 | 1258.0 | 35.6 | 35.6 | Plant productivity and environment. | J S Boyer | Science | 1982 | 17808529 | Yes |
2745 | 1257 | 1257.0 | 35.91 | 35.9 | Strategy and tactics in protein chemistry. | B S Hartley | Biochem J | 1970 | 4923920 | No |
2746 | 2513 | 1256.5 | 152.62 | 76.3 | A joint coordinate system for the clinical description of three-dimensional motions: application to the knee. | E S Grood, W J Suntay | J Biomech Eng | 1983 | 6865355 | Yes |
2747 | 1256 | 1256.0 | 36.02 | 36.0 | Peptide antibiotics and their role in innate immunity. | H G Boman | Annu Rev Immunol | 1995 | 7612236 | No |
2748 | 1256 | 1256.0 | 29.65 | 29.6 | Reactive oxygen radicals in signaling and damage in the ischemic brain. | P H Chan | J Cereb Blood Flow Metab | 2001 | 11149664 | No |
2749 | 2512 | 1256.0 | 51.02 | 25.5 | ERBB receptors and cancer: the complexity of targeted inhibitors. | Nancy E Hynes, Heidi A Lane | Nat Rev Cancer | 2005 | 15864276 | No |
2750 | 5020 | 1255.0 | 144.57 | 36.1 | Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma. | N Weidner, J P Semple, W R Welch, J Folkman | N Engl J Med | 1991 | 1701519 | Yes |
2751 | 2510 | 1255.0 | 72.8 | 36.4 | Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. | J I Morgan, T Curran | Annu Rev Neurosci | 1991 | 1903243 | No |
2752 | 1255 | 1255.0 | 0.0 | 0.0 | A simple objective technique for measuring flexibility in thinking. | E A Berg | J Gen Psychol | 1948 | 18889466 | Yes |
2753 | 1254 | 1254.0 | 34.23 | 34.2 | Internal models for motor control and trajectory planning. | M Kawato | Curr Opin Neurobiol | 1999 | 10607637 | No |
2754 | 1254 | 1254.0 | 33.13 | 33.1 | Persister cells, dormancy and infectious disease. | Kim Lewis | Nat Rev Microbiol | 2007 | 17143318 | No |
2755 | 3761 | 1253.7 | 110.96 | 37.0 | The functional anatomy of basal ganglia disorders. | R L Albin, A B Young, J B Penney | Trends Neurosci | 1989 | 2479133 | No |
2756 | 2507 | 1253.5 | 213.58 | 106.8 | Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: retrospective and prospective analyses. | R B Gustilo, J T Anderson | J Bone Joint Surg Am | 1976 | 773941 | Yes |
2757 | 2507 | 1253.5 | 47.05 | 23.5 | The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. | T Maehama, J E Dixon | J Biol Chem | 1998 | 9593664 | Yes |
2758 | 2505 | 1252.5 | 57.84 | 28.9 | DNA sequence analysis with a modified bacteriophage T7 DNA polymerase. | S Tabor, C C Richardson | Proc Natl Acad Sci U S A | 1987 | 3474623 | Yes |
2759 | 1252 | 1252.0 | 26.22 | 26.2 | Nucleic acid junctions and lattices. | N C Seeman | J Theor Biol | 1982 | 6188926 | Yes |
2760 | 1252 | 1252.0 | 42.07 | 42.1 | Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells. | R Lotan | Biochim Biophys Acta | 1980 | 6989400 | No |
2761 | 1252 | 1252.0 | 24.77 | 24.8 | STATs: signal transducers and activators of transcription. | J N Ihle | Cell | 1996 | 8608586 | No |
2762 | 1252 | 1252.0 | 42.74 | 42.7 | Inhibition and facilitation of nucleic acid amplification. | I G Wilson | Appl Environ Microbiol | 1997 | 9327537 | No |
2763 | 1252 | 1252.0 | 26.77 | 26.8 | Molecular physiology of low-voltage-activated t-type calcium channels. | Edward Perez-Reyes | Physiol Rev | 2003 | 12506128 | No |
2764 | 1252 | 1252.0 | 53.69 | 53.7 | Environmentally induced oxidative stress in aquatic animals. | Volodymyr I Lushchak | Aquat Toxicol | 2011 | 21074869 | No |
2765 | 3755 | 1251.7 | 112.08 | 37.4 | Oxidants, antioxidants, and the degenerative diseases of aging. | B N Ames, M K Shigenaga, T M Hagen | Proc Natl Acad Sci U S A | 1993 | 8367443 | No |
2766 | 1251 | 1251.0 | 27.27 | 27.3 | S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles. | R Donato | Int J Biochem Cell Biol | 2001 | 11390274 | No |
2767 | 1250 | 1250.0 | 62.72 | 62.7 | Assessment of chronic pain. I. Aspects of the reliability and validity of the visual analogue scale. | Anna Maria Carlsson | Pain | 1983 | 6602967 | Yes |
2768 | 1250 | 1250.0 | 47.94 | 47.9 | Minority stress and mental health in gay men. | I H Meyer | J Health Soc Behav | 1995 | 7738327 | Yes |
2769 | 2499 | 1249.5 | 68.91 | 34.5 | Nitric oxide synthases: roles, tolls, and controls. | C Nathan, Q W Xie | Cell | 1994 | 7522969 | No |
2770 | 4998 | 1249.5 | 116.04 | 29.0 | Autophagy fights disease through cellular self-digestion. | Noboru Mizushima, Beth Levine, Ana Maria Cuervo, Daniel J Klionsky | Nature | 2008 | 18305538 | No |
2771 | 1249 | 1249.0 | 82.6 | 82.6 | The problem of rigor in qualitative research. | M Sandelowski | ANS Adv Nurs Sci | 1986 | 3083765 | Yes |
2772 | 2498 | 1249.0 | 65.85 | 32.9 | Epidemiology and outcomes of osteoporotic fractures. | Steven R Cummings, L Joseph Melton | Lancet | 2002 | 12049882 | No |
2773 | 1249 | 1249.0 | 34.71 | 34.7 | Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes--a meta-analysis. | P Vestergaard | Osteoporos Int | 2007 | 17068657 | No |
2774 | 1249 | 1249.0 | 38.36 | 38.4 | Understanding diagnostic tests 3: Receiver operating characteristic curves. | Anthony K Akobeng | Acta Paediatr | 2007 | 17376185 | No |
2775 | 2497 | 1248.5 | 48.69 | 24.3 | Gene silencing in cancer in association with promoter hypermethylation. | James G Herman, Stephen B Baylin | N Engl J Med | 2003 | 14627790 | No |
2776 | 6242 | 1248.4 | 285.81 | 57.2 | BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs. | Felipe A Simão, Robert M Waterhouse, Panagiotis Ioannidis, Evgenia V Kriventseva, Evgeny M Zdobnov | Bioinformatics | 2015 | 26059717 | Yes |
2777 | 4993 | 1248.2 | 105.26 | 26.3 | Interleukin-10 and the interleukin-10 receptor. | K W Moore, R de Waal Malefyt, R L Coffman, A O'Garra | Annu Rev Immunol | 2001 | 11244051 | No |
2778 | 2496 | 1248.0 | 94.91 | 47.5 | Cronbach's alpha. | J M Bland, D G Altman | BMJ | 1997 | 9055718 | Yes |
2779 | 1248 | 1248.0 | 28.31 | 28.3 | Evaluating medication effects outside of clinical trials: new-user designs. | Wayne A Ray | Am J Epidemiol | 2003 | 14585769 | Yes |
2780 | 3744 | 1248.0 | 103.79 | 34.6 | Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. | Günter Oberdörster, Eva Oberdörster, Jan Oberdörster | Environ Health Perspect | 2005 | 16002369 | No |
2781 | 1248 | 1248.0 | 25.96 | 26.0 | The roles of intracellular protein-degradation pathways in neurodegeneration. | David C Rubinsztein | Nature | 2006 | 17051204 | No |
2782 | 1248 | 1248.0 | 31.3 | 31.3 | TNF-mediated inflammatory disease. | J R Bradley | J Pathol | 2008 | 18161752 | No |
2783 | 13727 | 1247.9 | 328.04 | 29.8 | New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. | P Therasse, S G Arbuck, E A Eisenhauer, J Wanders, R S Kaplan, L Rubinstein, J Verweij, M Van Glabbeke, A T van Oosterom, M C Christian, S G Gwyther | J Natl Cancer Inst | 2000 | 10655437 | No |
2784 | 1247 | 1247.0 | 57.42 | 57.4 | A cognitive approach to panic. | D M Clark | Behav Res Ther | 1986 | 3741311 | Yes |
2785 | 1247 | 1247.0 | 30.89 | 30.9 | Optimal experimental design for event-related fMRI. | A M Dale | Hum Brain Mapp | 1999 | 10524601 | Yes |
2786 | 1247 | 1247.0 | 35.95 | 36.0 | Subcutaneous and visceral adipose tissue: structural and functional differences. | M Mohsen Ibrahim | Obes Rev | 2010 | 19656312 | No |
2787 | 1247 | 1247.0 | 38.95 | 39.0 | Nanobodies: natural single-domain antibodies. | Serge Muyldermans | Annu Rev Biochem | 2013 | 23495938 | No |
2788 | 1247 | 1247.0 | 71.91 | 71.9 | DLS and zeta potential - What they are and what they are not? | Sourav Bhattacharjee | J Control Release | 2016 | 27297779 | No |
2789 | 2493 | 1246.5 | 63.59 | 31.8 | Hydrogels for tissue engineering: scaffold design variables and applications. | Jeanie L Drury, David J Mooney | Biomaterials | 2003 | 12922147 | No |
2790 | 2493 | 1246.5 | 62.76 | 31.4 | Nanostructures in biodiagnostics. | Nathaniel L Rosi, Chad A Mirkin | Chem Rev | 2005 | 15826019 | No |
2791 | 8725 | 1246.4 | 220.6 | 31.5 | Integrative genomics viewer. | James T Robinson, Helga Thorvaldsdóttir, Wendy Winckler, Mitchell Guttman, Eric S Lander, Gad Getz, Jill P Mesirov | Nat Biotechnol | 2011 | 21221095 | Yes |
2792 | 1246 | 1246.0 | 24.41 | 24.4 | Cytokines induce the development of functionally heterogeneous T helper cell subsets. | A O'Garra | Immunity | 1998 | 9529145 | No |
2793 | 2491 | 1245.5 | 63.32 | 31.7 | Genetic dissection of complex traits. | E S Lander, N J Schork | Science | 1994 | 8091226 | No |
2794 | 1245 | 1245.0 | 23.46 | 23.5 | Neuron-glia relationship during granule cell migration in developing cerebellar cortex. A Golgi and electronmicroscopic study in Macacus Rhesus. | P Rakic | J Comp Neurol | 1971 | 4101340 | Yes |
2795 | 1245 | 1245.0 | 41.9 | 41.9 | How is the level of free arachidonic acid controlled in mammalian cells? | R F Irvine | Biochem J | 1982 | 6810878 | No |
2796 | 1245 | 1245.0 | 32.62 | 32.6 | The lipocalin protein family: structure and function. | D R Flower | Biochem J | 1996 | 8761444 | No |
2797 | 1244 | 1244.0 | 34.6 | 34.6 | The effects of stressful life events on depression. | R C Kessler | Annu Rev Psychol | 1997 | 9046559 | No |
2798 | 2487 | 1243.5 | 61.63 | 30.8 | Molecular mechanisms of action of steroid/thyroid receptor superfamily members. | M J Tsai, B W O'Malley | Annu Rev Biochem | 1994 | 7979245 | No |
2799 | 2487 | 1243.5 | 79.8 | 39.9 | The short-form version of the Depression Anxiety Stress Scales (DASS-21): construct validity and normative data in a large non-clinical sample. | Julie D Henry, John R Crawford | Br J Clin Psychol | 2005 | 16004657 | Yes |
2800 | 7461 | 1243.5 | 215.27 | 35.9 | Free radicals and antioxidants in normal physiological functions and human disease. | Marian Valko, Dieter Leibfritz, Jan Moncol, Mark T D Cronin, Milan Mazur, Joshua Telser | Int J Biochem Cell Biol | 2007 | 16978905 | No |
2801 | 1243 | 1243.0 | 30.28 | 30.3 | Program DYNAFIT for the analysis of enzyme kinetic data: application to HIV proteinase. | P Kuzmic | Anal Biochem | 1996 | 8660575 | Yes |
2802 | 1243 | 1243.0 | 28.52 | 28.5 | Optical microcavities. | Kerry J Vahala | Nature | 2003 | 12917698 | Yes |
2803 | 1243 | 1243.0 | 46.85 | 46.9 | Microtiter dish biofilm formation assay. | George A O'Toole | J Vis Exp | 2011 | 21307833 | Yes |
2804 | 2484 | 1242.0 | 90.19 | 45.1 | The stunned myocardium: prolonged, postischemic ventricular dysfunction. | E Braunwald, R A Kloner | Circulation | 1982 | 6754130 | No |
2805 | 1242 | 1242.0 | 89.31 | 89.3 | SARS-CoV-2 vaccines in development. | Florian Krammer | Nature | 2020 | 32967006 | No |
2806 | 2483 | 1241.5 | 64.58 | 32.3 | Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. | Barry J Everitt, Trevor W Robbins | Nat Neurosci | 2005 | 16251991 | No |
2807 | 1241 | 1241.0 | 35.85 | 35.9 | Invasive aspergillosis. | D W Denning | Clin Infect Dis | 1998 | 9564455 | No |
2808 | 3723 | 1241.0 | 87.62 | 29.2 | Global and societal implications of the diabetes epidemic. | P Zimmet, K G Alberti, J Shaw | Nature | 2001 | 11742409 | No |
2809 | 1241 | 1241.0 | 0.0 | 0.0 | Intra-sexual selection in Drosophila. | A J Bateman | Heredity (Edinb) | 1948 | 18103134 | Yes |
2810 | 3722 | 1240.7 | 116.39 | 38.8 | MR diffusion tensor spectroscopy and imaging. | P J Basser, J Mattiello, D LeBihan | Biophys J | 1994 | 8130344 | Yes |
2811 | 6203 | 1240.6 | 248.54 | 49.7 | The Phyre2 web portal for protein modeling, prediction and analysis. | Lawrence A Kelley, Stefans Mezulis, Christopher M Yates, Mark N Wass, Michael J E Sternberg | Nat Protoc | 2015 | 25950237 | Yes |
2812 | 1240 | 1240.0 | 37.81 | 37.8 | Calcium channel modulation by neurotransmitters, enzymes and drugs. | H Reuter | Nature | 1983 | 6131381 | No |
2813 | 1240 | 1240.0 | 31.8 | 31.8 | Drug delivery and targeting. | R Langer | Nature | 1998 | 9579855 | No |
2814 | 1240 | 1240.0 | 0.0 | 0.0 | A modification of receptor theory. | R P Stephenson | Br J Pharmacol Chemother | 1956 | 13383117 | Yes |
2815 | 1239 | 1239.0 | 26.01 | 26.0 | Antigen-presenting function of the macrophage. | E R Unanue | Annu Rev Immunol | 1984 | 6242349 | No |
2816 | 1239 | 1239.0 | 35.25 | 35.2 | Varieties of impulsivity. | J L Evenden | Psychopharmacology (Berl) | 1999 | 10550486 | No |
2817 | 2478 | 1239.0 | 48.26 | 24.1 | Proliferation, cell cycle and apoptosis in cancer. | G I Evan, K H Vousden | Nature | 2001 | 11357141 | No |
2818 | 1239 | 1239.0 | 30.26 | 30.3 | Primate anterior cingulate cortex: where motor control, drive and cognition interface. | T Paus | Nat Rev Neurosci | 2001 | 11389475 | No |
2819 | 2478 | 1239.0 | 61.42 | 30.7 | Hydrogels for tissue engineering. | K Y Lee, D J Mooney | Chem Rev | 2001 | 11710233 | No |
2820 | 3714 | 1238.0 | 71.83 | 23.9 | Exosomes: composition, biogenesis and function. | Clotilde Théry, Laurence Zitvogel, Sebastian Amigorena | Nat Rev Immunol | 2002 | 12154376 | No |
2821 | 1238 | 1238.0 | 38.0 | 38.0 | Risk and maintenance factors for eating pathology: a meta-analytic review. | Eric Stice | Psychol Bull | 2002 | 12206196 | No |
2822 | 1238 | 1238.0 | 26.42 | 26.4 | Assortative mixing in networks. | M E J Newman | Phys Rev Lett | 2002 | 12443515 | Yes |
2823 | 2476 | 1238.0 | 53.19 | 26.6 | Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. | Eugenia E Calle, Rudolf Kaaks | Nat Rev Cancer | 2004 | 15286738 | No |
2824 | 2476 | 1238.0 | 103.45 | 51.7 | Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities. | Roel Nusse, Hans Clevers | Cell | 2017 | 28575679 | No |
2825 | 2474 | 1237.0 | 47.73 | 23.9 | Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. | C W Greider, E H Blackburn | Cell | 1985 | 3907856 | Yes |
2826 | 1237 | 1237.0 | 32.0 | 32.0 | Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome: a summary of the evidence. | Earl S Ford | Diabetes Care | 2005 | 15983333 | No |
2827 | 2473 | 1236.5 | 53.42 | 26.7 | The role of polyamines in the neutralization of bacteriophage deoxyribonucleic acid. | B N Ames, D T Dubin | J Biol Chem | 1960 | 13793161 | Yes |
2828 | 1236 | 1236.0 | 0.0 | 0.0 | Sequential tests for the detection of linkage. | N E Morton | Am J Hum Genet | 1955 | 13258560 | Yes |
2829 | 3708 | 1236.0 | 104.33 | 34.8 | The Patient Health Questionnaire-2: validity of a two-item depression screener. | Kurt Kroenke, Robert L Spitzer, Janet B W Williams | Med Care | 2003 | 14583691 | Yes |
2830 | 1236 | 1236.0 | 34.95 | 35.0 | Targeting recovery: priorities of the spinal cord-injured population. | Kim D Anderson | J Neurotrauma | 2004 | 15672628 | Yes |
2831 | 2472 | 1236.0 | 67.85 | 33.9 | The cognitive control of emotion. | Kevin N Ochsner, James J Gross | Trends Cogn Sci | 2005 | 15866151 | No |
2832 | 1235 | 1235.0 | 32.4 | 32.4 | Thermo- and pH-responsive polymers in drug delivery. | Dirk Schmaljohann | Adv Drug Deliv Rev | 2006 | 17125884 | No |
2833 | 1235 | 1235.0 | 40.38 | 40.4 | Function and information content of DNA methylation. | Dirk Schübeler | Nature | 2015 | 25592537 | No |
2834 | 2469 | 1234.5 | 101.64 | 50.8 | Reading senseless sentences: brain potentials reflect semantic incongruity. | M Kutas, S A Hillyard | Science | 1980 | 7350657 | Yes |
2835 | 1234 | 1234.0 | 51.36 | 51.4 | A cochlear frequency-position function for several species--29 years later. | D D Greenwood | J Acoust Soc Am | 1990 | 2373794 | Yes |
2836 | 1234 | 1234.0 | 38.59 | 38.6 | Antioxidants in human health and disease. | B Halliwell | Annu Rev Nutr | 1996 | 8839918 | No |
2837 | 1234 | 1234.0 | 0.0 | 0.0 | The relation of the trail making test to organic brain damage. | R M Reitan | J Consult Psychol | 1955 | 13263471 | Yes |
2838 | 1234 | 1234.0 | 30.01 | 30.0 | Electrochemiluminescence (ECL). | Mark M Richter | Chem Rev | 2004 | 15186186 | No |
2839 | 2468 | 1234.0 | 66.37 | 33.2 | Increasing incidence of thyroid cancer in the United States, 1973-2002. | Louise Davies, H Gilbert Welch | JAMA | 2006 | 16684987 | Yes |
2840 | 1234 | 1234.0 | 52.75 | 52.8 | The Laboratory Rat: Relating Its Age With Human's. | Pallav Sengupta | Int J Prev Med | 2013 | 23930179 | Yes |
2841 | 2467 | 1233.5 | 48.29 | 24.1 | Checkpoints: controls that ensure the order of cell cycle events. | L H Hartwell, T A Weinert | Science | 1989 | 2683079 | No |
2842 | 2467 | 1233.5 | 62.22 | 31.1 | Epidemiology of Parkinson's disease. | Lonneke M L de Lau, Monique M B Breteler | Lancet Neurol | 2006 | 16713924 | No |
2843 | 8633 | 1233.3 | 254.71 | 36.4 | Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. | H P Adams, B H Bendixen, L J Kappelle, J Biller, B B Love, D L Gordon, E E Marsh | Stroke | 1993 | 7678184 | Yes |
2844 | 3700 | 1233.3 | 140.52 | 46.8 | Visible light photoredox catalysis with transition metal complexes: applications in organic synthesis. | Christopher K Prier, Danica A Rankic, David W C MacMillan | Chem Rev | 2013 | 23509883 | No |
2845 | 4933 | 1233.2 | 130.45 | 32.6 | Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. | Michael J Pencina, Ralph B D'Agostino, Ralph B D'Agostino, Ramachandran S Vasan | Stat Med | 2008 | 17569110 | Yes |
2846 | 1233 | 1233.0 | 27.5 | 27.5 | Neurobiology of Pavlovian fear conditioning. | S Maren | Annu Rev Neurosci | 2001 | 11520922 | No |
2847 | 2465 | 1232.5 | 66.09 | 33.0 | Meeting of minds: the medial frontal cortex and social cognition. | David M Amodio, Chris D Frith | Nat Rev Neurosci | 2006 | 16552413 | No |
2848 | 2464 | 1232.0 | 55.43 | 27.7 | Cellular processing of platinum anticancer drugs. | Dong Wang, Stephen J Lippard | Nat Rev Drug Discov | 2005 | 15789122 | No |
2849 | 6157 | 1231.4 | 192.77 | 38.6 | Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. | J S Beckman, T W Beckman, J Chen, P A Marshall, B A Freeman | Proc Natl Acad Sci U S A | 1990 | 2154753 | Yes |
2850 | 1231 | 1231.0 | 32.37 | 32.4 | Low density lipoprotein oxidation and its pathobiological significance. | D Steinberg | J Biol Chem | 1997 | 9261091 | No |
2851 | 1231 | 1231.0 | 26.6 | 26.6 | Nuclear factor-kappaB: the enemy within. | Bharat B Aggarwal | Cancer Cell | 2004 | 15380510 | No |
2852 | 1231 | 1231.0 | 37.86 | 37.9 | Evaluating the quality of medical care. 1966. | Avedis Donabedian | Milbank Q | 2005 | 16279964 | No |
2853 | 1231 | 1231.0 | 33.37 | 33.4 | Infection in solid-organ transplant recipients. | Jay A Fishman | N Engl J Med | 2007 | 18094380 | No |
2854 | 1231 | 1231.0 | 26.42 | 26.4 | Hypoxia, HIF1 and glucose metabolism in the solid tumour. | Nicholas C Denko | Nat Rev Cancer | 2008 | 19143055 | No |
2855 | 1230 | 1230.0 | 41.79 | 41.8 | Physiological implications of hydrogen sulfide: a whiff exploration that blossomed. | Rui Wang | Physiol Rev | 2012 | 22535897 | No |
2856 | 2459 | 1229.5 | 64.73 | 32.4 | A review of central 5-HT receptors and their function. | N M Barnes, T Sharp | Neuropharmacology | 1999 | 10462127 | No |
2857 | 2459 | 1229.5 | 62.35 | 31.2 | An integrative theory of locus coeruleus-norepinephrine function: adaptive gain and optimal performance. | Gary Aston-Jones, Jonathan D Cohen | Annu Rev Neurosci | 2005 | 16022602 | No |
2858 | 1229 | 1229.0 | 44.14 | 44.1 | Transduction of psychosocial stress into the neurobiology of recurrent affective disorder. | R M Post | Am J Psychiatry | 1992 | 1353322 | No |
2859 | 2458 | 1229.0 | 68.22 | 34.1 | Ageing and Parkinson's disease: substantia nigra regional selectivity. | J M Fearnley, A J Lees | Brain | 1991 | 1933245 | Yes |
2860 | 1229 | 1229.0 | 43.82 | 43.8 | The LMS method for constructing normalized growth standards. | T J Cole | Eur J Clin Nutr | 1990 | 2354692 | Yes |
2861 | 2458 | 1229.0 | 56.93 | 28.5 | Peroxisome proliferator-activated receptors: nuclear control of metabolism. | B Desvergne, W Wahli | Endocr Rev | 1999 | 10529898 | No |
2862 | 1228 | 1228.0 | 21.88 | 21.9 | Mutation selection and the natural history of cancer. | J Cairns | Nature | 1975 | 1143315 | Yes |
2863 | 2456 | 1228.0 | 75.98 | 38.0 | Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. | J E Hixson, D T Vernier | J Lipid Res | 1990 | 2341813 | Yes |
2864 | 1228 | 1228.0 | 55.34 | 55.3 | Continuous improvement as an ideal in health care. | D M Berwick | N Engl J Med | 1989 | 2909878 | Yes |
2865 | 1228 | 1228.0 | 33.12 | 33.1 | Current source-density method and application in cat cerebral cortex: investigation of evoked potentials and EEG phenomena. | U Mitzdorf | Physiol Rev | 1985 | 3880898 | No |
2866 | 1228 | 1228.0 | 22.73 | 22.7 | Histone-deacetylase inhibitors: novel drugs for the treatment of cancer. | Ricky W Johnstone | Nat Rev Drug Discov | 2002 | 12120280 | No |
2867 | 1228 | 1228.0 | 40.06 | 40.1 | Photoplethysmography and its application in clinical physiological measurement. | John Allen | Physiol Meas | 2007 | 17322588 | No |
2868 | 2455 | 1227.5 | 39.29 | 19.6 | A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. | D Tautz, C Pfeifle | Chromosoma | 1989 | 2476281 | Yes |
2869 | 2455 | 1227.5 | 63.21 | 31.6 | Biology of incretins: GLP-1 and GIP. | Laurie L Baggio, Daniel J Drucker | Gastroenterology | 2007 | 17498508 | No |
2870 | 1227 | 1227.0 | 32.12 | 32.1 | Preparation of rat liver cells. 3. Enzymatic requirements for tissue dispersion. | P O Seglen | Exp Cell Res | 1973 | 4358115 | Yes |
2871 | 1227 | 1227.0 | 18.54 | 18.5 | The concept of immunological surveillance. | F M Burnet | Prog Exp Tumor Res | 1970 | 4921480 | No |
2872 | 1227 | 1227.0 | 18.98 | 19.0 | The diagnosis of ischaemic heart pain and intermittent claudication in field surveys. | G A Rose | Bull World Health Organ | 1962 | 13974778 | Yes |
2873 | 3681 | 1227.0 | 109.7 | 36.6 | Health benefits of physical activity: the evidence. | Darren E R Warburton, Crystal Whitney Nicol, Shannon S D Bredin | CMAJ | 2006 | 16534088 | No |
2874 | 2453 | 1226.5 | 48.89 | 24.4 | Community structure in social and biological networks. | M Girvan, M E J Newman | Proc Natl Acad Sci U S A | 2002 | 12060727 | No |
2875 | 3679 | 1226.3 | 115.07 | 38.4 | Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS. | B K Matuszewski, M L Constanzer, C M Chavez-Eng | Anal Chem | 2003 | 12964746 | Yes |
2876 | 1226 | 1226.0 | 25.33 | 25.3 | MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. | R N Germain | Cell | 1994 | 8293464 | No |
2877 | 1226 | 1226.0 | 30.69 | 30.7 | Endothelial-leukocyte adhesion molecules. | M P Bevilacqua | Annu Rev Immunol | 1993 | 8476577 | No |
2878 | 2452 | 1226.0 | 43.33 | 21.7 | Stats: transcriptional control and biological impact. | David E Levy, J E Darnell | Nat Rev Mol Cell Biol | 2002 | 12209125 | No |
2879 | 1226 | 1226.0 | 52.2 | 52.2 | Receiver Operating Characteristic (ROC) Curve Analysis for Medical Diagnostic Test Evaluation. | Karimollah Hajian-Tilaki | Caspian J Intern Med | 2013 | 24009950 | No |
2880 | 1226 | 1226.0 | 67.63 | 67.6 | ROS Are Good. | Ron Mittler | Trends Plant Sci | 2017 | 27666517 | No |
2881 | 2451 | 1225.5 | 54.01 | 27.0 | Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange. | G K McMaster, G G Carmichael | Proc Natl Acad Sci U S A | 1977 | 73185 | Yes |
2882 | 1225 | 1225.0 | 32.09 | 32.1 | Measurement of feelings using visual analogue scales. | R C Aitken | Proc R Soc Med | 1969 | 4899510 | No |
2883 | 1225 | 1225.0 | 22.31 | 22.3 | Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture. | H E Ruley | Nature | 1983 | 6308473 | Yes |
2884 | 1225 | 1225.0 | 28.63 | 28.6 | A likelihood approach to estimating phylogeny from discrete morphological character data. | P O Lewis | Syst Biol | 2001 | 12116640 | Yes |
2885 | 1225 | 1225.0 | 31.03 | 31.0 | Polymer conjugates as anticancer nanomedicines. | Ruth Duncan | Nat Rev Cancer | 2006 | 16900224 | No |
2886 | 1224 | 1224.0 | 26.66 | 26.7 | Heterotrimeric G proteins: organizers of transmembrane signals. | E J Neer | Cell | 1995 | 7834744 | No |
2887 | 1224 | 1224.0 | 44.64 | 44.6 | Comfortable and maximum walking speed of adults aged 20-79 years: reference values and determinants. | R W Bohannon | Age Ageing | 1997 | 9143432 | Yes |
2888 | 1224 | 1224.0 | 28.74 | 28.7 | Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis. | R Balfour Sartor | Nat Clin Pract Gastroenterol Hepatol | 2006 | 16819502 | No |
2889 | 1224 | 1224.0 | 34.62 | 34.6 | T follicular helper cell differentiation, function, and roles in disease. | Shane Crotty | Immunity | 2014 | 25367570 | No |
2890 | 4892 | 1223.0 | 274.44 | 68.6 | Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm. | L A Papile, J Burstein, R Burstein, H Koffler | J Pediatr | 1978 | 305471 | Yes |
2891 | 1223 | 1223.0 | 63.01 | 63.0 | Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method. | K Satoh | Clin Chim Acta | 1978 | 719890 | Yes |
2892 | 1223 | 1223.0 | 26.11 | 26.1 | Microglia as a source and target of cytokines. | Uwe-Karsten Hanisch | Glia | 2002 | 12379902 | No |
2893 | 1223 | 1223.0 | 36.11 | 36.1 | Federal funding for the study of antimicrobial resistance in nosocomial pathogens: no ESKAPE. | Louis B Rice | J Infect Dis | 2008 | 18419525 | No |
2894 | 1223 | 1223.0 | 23.19 | 23.2 | ChIP-seq: advantages and challenges of a maturing technology. | Peter J Park | Nat Rev Genet | 2009 | 19736561 | No |
2895 | 1222 | 1222.0 | 43.28 | 43.3 | Experience from a multicentre stroke register: a preliminary report. | S Hatano | Bull World Health Organ | 1976 | 1088404 | Yes |
2896 | 1222 | 1222.0 | 30.85 | 30.9 | Neural systems for recognizing emotion. | Ralph Adolphs | Curr Opin Neurobiol | 2002 | 12015233 | No |
2897 | 2443 | 1221.5 | 65.29 | 32.6 | Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications. | M A Pfeffer, E Braunwald | Circulation | 1990 | 2138525 | No |
2898 | 1221 | 1221.0 | 33.76 | 33.8 | Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections. | F Hefti | J Neurosci | 1986 | 3746405 | Yes |
2899 | 1221 | 1221.0 | 37.13 | 37.1 | Delirium in older persons. | Sharon K Inouye | N Engl J Med | 2006 | 16540616 | No |
2900 | 1220 | 1220.0 | 48.66 | 48.7 | Bone "mass" and the "mechanostat": a proposal. | H M Frost | Anat Rec | 1987 | 3688455 | Yes |
2901 | 1220 | 1220.0 | 23.58 | 23.6 | Lipid rafts: elusive or illusive? | Sean Munro | Cell | 2003 | 14622593 | No |
2902 | 1220 | 1220.0 | 27.57 | 27.6 | Production of recombinant protein therapeutics in cultivated mammalian cells. | Florian M Wurm | Nat Biotechnol | 2004 | 15529164 | No |
2903 | 1219 | 1219.0 | 44.77 | 44.8 | The P300 wave of the human event-related potential. | T W Picton | J Clin Neurophysiol | 1992 | 1464675 | No |
2904 | 1219 | 1219.0 | 28.63 | 28.6 | Growth factors and cancer. | S A Aaronson | Science | 1991 | 1659742 | No |
2905 | 1219 | 1219.0 | 32.62 | 32.6 | Akaike's information criterion in generalized estimating equations. | W Pan | Biometrics | 2001 | 11252586 | Yes |
2906 | 13403 | 1218.5 | 345.62 | 31.4 | Frailty in older adults: evidence for a phenotype. | L P Fried, C M Tangen, J Walston, A B Newman, C Hirsch, J Gottdiener, T Seeman, R Tracy, W J Kop, G Burke, M A McBurnie | J Gerontol A Biol Sci Med Sci | 2001 | 11253156 | Yes |
2907 | 1218 | 1218.0 | 45.47 | 45.5 | A cognitive model of drug urges and drug-use behavior: role of automatic and nonautomatic processes. | S T Tiffany | Psychol Rev | 1990 | 2186423 | No |
2908 | 1218 | 1218.0 | 32.72 | 32.7 | Levels of racism: a theoretic framework and a gardener's tale. | C P Jones | Am J Public Health | 2000 | 10936998 | Yes |
2909 | 1218 | 1218.0 | 27.33 | 27.3 | Brain tumors. | L M DeAngelis | N Engl J Med | 2001 | 11150363 | No |
2910 | 2436 | 1218.0 | 87.31 | 43.7 | Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. | John F Cryan, Timothy G Dinan | Nat Rev Neurosci | 2012 | 22968153 | No |
2911 | 2436 | 1218.0 | 129.26 | 64.6 | Sensitivity Analysis in Observational Research: Introducing the E-Value. | Tyler J VanderWeele, Peng Ding | Ann Intern Med | 2017 | 28693043 | Yes |
2912 | 1217 | 1217.0 | 59.1 | 59.1 | ROC methodology in radiologic imaging. | C E Metz | Invest Radiol | 1986 | 3095258 | No |
2913 | 1217 | 1217.0 | 22.14 | 22.1 | Kinesin and dynein superfamily proteins and the mechanism of organelle transport. | N Hirokawa | Science | 1998 | 9438838 | No |
2914 | 1217 | 1217.0 | 25.09 | 25.1 | Platelets in atherothrombosis. | Zaverio M Ruggeri | Nat Med | 2002 | 12411949 | No |
2915 | 1217 | 1217.0 | 10.75 | 10.8 | Cumulative dose-response curves. II. Technique for the making of dose-response curves in isolated organs and the evaluation of drug parameters. | J M Van Rossum | Arch Int Pharmacodyn Ther | 1963 | 13996119 | Yes |
2916 | 2433 | 1216.5 | 48.03 | 24.0 | Molecular chaperones in the cytosol: from nascent chain to folded protein. | F Ulrich Hartl, Manajit Hayer-Hartl | Science | 2002 | 11884745 | No |
2917 | 2432 | 1216.0 | 78.58 | 39.3 | Atomic structure and chemistry of human serum albumin. | X M He, D C Carter | Nature | 1992 | 1630489 | Yes |
2918 | 1216 | 1216.0 | 44.49 | 44.5 | Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment. | S H Safe | Crit Rev Toxicol | 1994 | 8037844 | No |
2919 | 1216 | 1216.0 | 25.69 | 25.7 | Dendritic cells: unique leukocyte populations which control the primary immune response. | D N Hart | Blood | 1997 | 9345009 | No |
2920 | 2431 | 1215.5 | 18.83 | 9.4 | The Aggregation Of Blood Platelets. | G V Born, M J Cross | J Physiol | 1963 | 14056485 | Yes |
2921 | 3646 | 1215.3 | 61.49 | 20.5 | A system for stable expression of short interfering RNAs in mammalian cells. | Thijn R Brummelkamp, René Bernards, Reuven Agami | Science | 2002 | 11910072 | Yes |
2922 | 1215 | 1215.0 | 24.36 | 24.4 | Basement membranes: structure, assembly and role in tumour angiogenesis. | Raghu Kalluri | Nat Rev Cancer | 2003 | 12778132 | No |
2923 | 1215 | 1215.0 | 30.71 | 30.7 | Functionalized acenes and heteroacenes for organic electronics. | John E Anthony | Chem Rev | 2006 | 17165682 | Yes |
2924 | 2429 | 1214.5 | 86.67 | 43.3 | Nitric oxide synthases: regulation and function. | Ulrich Förstermann, William C Sessa | Eur Heart J | 2012 | 21890489 | No |
2925 | 3642 | 1214.0 | 179.31 | 59.8 | Assessing coping strategies: a theoretically based approach. | C S Carver, M F Scheier, J K Weintraub | J Pers Soc Psychol | 1989 | 2926629 | Yes |
2926 | 1214 | 1214.0 | 27.04 | 27.0 | Translating cell biology into therapeutic advances in Alzheimer's disease. | D J Selkoe | Nature | 1999 | 10392577 | No |
2927 | 1214 | 1214.0 | 29.27 | 29.3 | Plant salt tolerance. | J K Zhu | Trends Plant Sci | 2001 | 11173290 | Yes |
2928 | 1212 | 1212.0 | 20.24 | 20.2 | Mitotic kinases as regulators of cell division and its checkpoints. | E A Nigg | Nat Rev Mol Cell Biol | 2001 | 11413462 | No |
2929 | 1212 | 1212.0 | 33.35 | 33.4 | Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective. | Antoine Bechara | Nat Neurosci | 2005 | 16251988 | No |
2930 | 1211 | 1211.0 | 42.09 | 42.1 | Hydrophilic-interaction chromatography for the separation of peptides, nucleic acids and other polar compounds. | A J Alpert | J Chromatogr | 1990 | 2324207 | Yes |
2931 | 2422 | 1211.0 | 39.41 | 19.7 | High resolution acrylamide gel electrophoresis of histones. | S Panyim, R Chalkley | Arch Biochem Biophys | 1969 | 5778650 | Yes |
2932 | 1211 | 1211.0 | 24.88 | 24.9 | Morphogenetic roles of classic cadherins. | M Takeichi | Curr Opin Cell Biol | 1995 | 8573335 | No |
2933 | 6053 | 1210.6 | 147.51 | 29.5 | Jalview Version 2--a multiple sequence alignment editor and analysis workbench. | Andrew M Waterhouse, James B Procter, David M A Martin, Michèle Clamp, Geoffrey J Barton | Bioinformatics | 2009 | 19151095 | Yes |
2934 | 2421 | 1210.5 | 64.14 | 32.1 | A neurotrophic model for stress-related mood disorders. | Ronald S Duman, Lisa M Monteggia | Biol Psychiatry | 2006 | 16631126 | No |
2935 | 1210 | 1210.0 | 29.35 | 29.4 | Bcl-2 initiates a new category of oncogenes: regulators of cell death. | S J Korsmeyer | Blood | 1992 | 1498330 | No |
2936 | 1210 | 1210.0 | 25.13 | 25.1 | Caspase structure, proteolytic substrates, and function during apoptotic cell death. | D W Nicholson | Cell Death Differ | 1999 | 10578171 | No |
2937 | 1210 | 1210.0 | 31.65 | 31.6 | Chronic mild stress (CMS) revisited: consistency and behavioural-neurobiological concordance in the effects of CMS. | Paul Willner | Neuropsychobiology | 2005 | 16037678 | No |
2938 | 1210 | 1210.0 | 34.72 | 34.7 | High prevalence of vitamin D inadequacy and implications for health. | Michael F Holick | Mayo Clin Proc | 2006 | 16529140 | No |
2939 | 2419 | 1209.5 | 72.62 | 36.3 | Inflammatory mechanisms in obesity. | Margaret F Gregor, Gökhan S Hotamisligil | Annu Rev Immunol | 2011 | 21219177 | No |
2940 | 2419 | 1209.5 | 97.14 | 48.6 | Unique features of long non-coding RNA biogenesis and function. | Jeffrey J Quinn, Howard Y Chang | Nat Rev Genet | 2016 | 26666209 | No |
2941 | 9666 | 1208.2 | 249.68 | 31.2 | A method and server for predicting damaging missense mutations. | Ivan A Adzhubei, Steffen Schmidt, Leonid Peshkin, Vasily E Ramensky, Anna Gerasimova, Peer Bork, Alexey S Kondrashov, Shamil R Sunyaev | Nat Methods | 2010 | 20354512 | Yes |
2942 | 1208 | 1208.0 | 28.71 | 28.7 | Rapid and sensitive sequence comparison with FASTP and FASTA. | W R Pearson | Methods Enzymol | 1990 | 2156132 | Yes |
2943 | 2416 | 1208.0 | 52.63 | 26.3 | Toll-like receptors in innate immunity. | Kiyoshi Takeda, Shizuo Akira | Int Immunol | 2005 | 15585605 | No |
2944 | 1208 | 1208.0 | 33.66 | 33.7 | Water as an active constituent in cell biology. | Philip Ball | Chem Rev | 2008 | 18095715 | No |
2945 | 1208 | 1208.0 | 34.29 | 34.3 | Electrochemical glucose biosensors. | Joseph Wang | Chem Rev | 2008 | 18154363 | No |
2946 | 1208 | 1208.0 | 37.84 | 37.8 | Clinical practice. Endometriosis. | Linda C Giudice | N Engl J Med | 2010 | 20573927 | No |
2947 | 1208 | 1208.0 | 52.68 | 52.7 | Inflammation, metaflammation and immunometabolic disorders. | Gökhan S Hotamisligil | Nature | 2017 | 28179656 | No |
2948 | 7244 | 1207.3 | 135.72 | 22.6 | Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. | S M Elbashir, J Harborth, W Lendeckel, A Yalcin, K Weber, T Tuschl | Nature | 2001 | 11373684 | Yes |
2949 | 1207 | 1207.0 | 48.45 | 48.5 | Bacterial adherence: adhesin-receptor interactions mediating the attachment of bacteria to mucosal surface. | E H Beachey | J Infect Dis | 1981 | 7014727 | No |
2950 | 1207 | 1207.0 | 24.71 | 24.7 | Fibrotic disease and the T(H)1/T(H)2 paradigm. | Thomas A Wynn | Nat Rev Immunol | 2004 | 15286725 | No |
2951 | 1207 | 1207.0 | 23.1 | 23.1 | IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. | Yong-Jun Liu | Annu Rev Immunol | 2005 | 15771572 | No |
2952 | 2413 | 1206.5 | 101.86 | 50.9 | The Warburg Effect: How Does it Benefit Cancer Cells? | Maria V Liberti, Jason W Locasale | Trends Biochem Sci | 2016 | 26778478 | No |
2953 | 1206 | 1206.0 | 38.11 | 38.1 | Linkage map of Escherichia coli K-12, edition 7. | B J Bachmann | Microbiol Rev | 1983 | 6348505 | No |
2954 | 4823 | 1205.8 | 185.63 | 46.4 | Predicting effective microRNA target sites in mammalian mRNAs. | Vikram Agarwal, George W Bell, Jin-Wu Nam, David P Bartel | Elife | 2015 | 26267216 | Yes |
2955 | 3617 | 1205.7 | 72.9 | 24.3 | Large-scale analysis of the yeast proteome by multidimensional protein identification technology. | M P Washburn, D Wolters, J R Yates | Nat Biotechnol | 2001 | 11231557 | Yes |
2956 | 2411 | 1205.5 | 59.84 | 29.9 | Rising incidence of hepatocellular carcinoma in the United States. | H B El-Serag, A C Mason | N Engl J Med | 1999 | 10072408 | Yes |
2957 | 3616 | 1205.3 | 113.73 | 37.9 | Qualitative research in health care. Analysing qualitative data. | C Pope, S Ziebland, N Mays | BMJ | 2000 | 10625273 | No |
2958 | 2410 | 1205.0 | 96.8 | 48.4 | The N1 wave of the human electric and magnetic response to sound: a review and an analysis of the component structure. | R Näätänen, T Picton | Psychophysiology | 1987 | 3615753 | Yes |
2959 | 1205 | 1205.0 | 28.19 | 28.2 | Intracellular protein topogenesis. | G Blobel | Proc Natl Acad Sci U S A | 1980 | 6929499 | Yes |
2960 | 1205 | 1205.0 | 37.3 | 37.3 | Sensorimotor integration in human postural control. | R J Peterka | J Neurophysiol | 2002 | 12205132 | Yes |
2961 | 2410 | 1205.0 | 57.24 | 28.6 | Principles of bioactive lipid signalling: lessons from sphingolipids. | Yusuf A Hannun, Lina M Obeid | Nat Rev Mol Cell Biol | 2008 | 18216770 | No |
2962 | 3613 | 1204.3 | 101.64 | 33.9 | Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. | H King, R E Aubert, W H Herman | Diabetes Care | 1998 | 9727886 | Yes |
2963 | 1204 | 1204.0 | 29.24 | 29.2 | The neuropathology of schizophrenia. A critical review of the data and their interpretation. | P J Harrison | Brain | 1999 | 10219775 | No |
2964 | 1204 | 1204.0 | 48.9 | 48.9 | The variable nature of cognitive control: a dual mechanisms framework. | Todd S Braver | Trends Cogn Sci | 2012 | 22245618 | Yes |
2965 | 4815 | 1203.8 | 111.95 | 28.0 | Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. | G L Wang, B H Jiang, E A Rue, G L Semenza | Proc Natl Acad Sci U S A | 1995 | 7539918 | Yes |
2966 | 2407 | 1203.5 | 74.16 | 37.1 | A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data. | A Ennaceur, J Delacour | Behav Brain Res | 1988 | 3228475 | Yes |
2967 | 2407 | 1203.5 | 82.63 | 41.3 | Factors affecting wound healing. | S Guo, L A Dipietro | J Dent Res | 2010 | 20139336 | No |
2968 | 1203 | 1203.0 | 29.66 | 29.7 | Automatic quantitation of localized in vivo 1H spectra with LCModel. | S W Provencher | NMR Biomed | 2001 | 11410943 | Yes |
2969 | 4811 | 1202.8 | 153.76 | 38.4 | Validation of a combined comorbidity index. | M Charlson, T P Szatrowski, J Peterson, J Gold | J Clin Epidemiol | 1994 | 7722560 | Yes |
2970 | 1202 | 1202.0 | 25.66 | 25.7 | The finer things in X-ray diffraction data collection. | J W Pflugrath | Acta Crystallogr D Biol Crystallogr | 1999 | 10531521 | Yes |
2971 | 1202 | 1202.0 | 30.81 | 30.8 | The complex role of estrogens in inflammation. | Rainer H Straub | Endocr Rev | 2007 | 17640948 | No |
2972 | 3604 | 1201.3 | 86.55 | 28.8 | Functional diversity of helper T lymphocytes. | A K Abbas, K M Murphy, A Sher | Nature | 1996 | 8893001 | No |
2973 | 1201 | 1201.0 | 39.28 | 39.3 | Assay of intestinal disaccharidases. | A Dahlqvist | Anal Biochem | 1968 | 5636962 | Yes |
2974 | 1201 | 1201.0 | 21.33 | 21.3 | Studies on phosphatidylcholine vesicles. Formation and physical characteristics. | C Huang | Biochemistry | 1969 | 5777332 | Yes |
2975 | 1201 | 1201.0 | 27.11 | 27.1 | Mitochondrial transport of cations: channels, exchangers, and permeability transition. | P Bernardi | Physiol Rev | 1999 | 10508231 | No |
2976 | 1201 | 1201.0 | 37.63 | 37.6 | Socioeconomic status and obesity. | Lindsay McLaren | Epidemiol Rev | 2007 | 17478442 | No |
2977 | 2401 | 1200.5 | 243.71 | 121.9 | The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. | Hussin A Rothan, Siddappa N Byrareddy | J Autoimmun | 2020 | 32113704 | No |
2978 | 4801 | 1200.2 | 240.71 | 60.2 | Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range. | Xiang Wan, Wenqian Wang, Jiming Liu, Tiejun Tong | BMC Med Res Methodol | 2014 | 25524443 | Yes |
2979 | 2400 | 1200.0 | 70.8 | 35.4 | Recent advances in the phencyclidine model of schizophrenia. | D C Javitt, S R Zukin | Am J Psychiatry | 1991 | 1654746 | No |
2980 | 2400 | 1200.0 | 53.35 | 26.7 | Transforming gene product of Rous sarcoma virus phosphorylates tyrosine. | T Hunter, B M Sefton | Proc Natl Acad Sci U S A | 1980 | 6246487 | Yes |
2981 | 2400 | 1200.0 | 64.11 | 32.1 | Leukocyte-endothelial adhesion molecules. | T M Carlos, J M Harlan | Blood | 1994 | 7522621 | No |
2982 | 1200 | 1200.0 | 45.65 | 45.6 | Glutathione synthesis. | Shelly C Lu | Biochim Biophys Acta | 2013 | 22995213 | No |
2983 | 1199 | 1199.0 | 52.2 | 52.2 | Campylobacter enteritis: a "new" disease. | M B Skirrow | Br Med J | 1977 | 871765 | Yes |
2984 | 1199 | 1199.0 | 38.21 | 38.2 | The pathogenesis of sepsis. | R C Bone | Ann Intern Med | 1991 | 1872494 | No |
2985 | 1199 | 1199.0 | 20.45 | 20.4 | Biochemical adaptations in muscle. Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle. | J O Holloszy | J Biol Chem | 1967 | 4290225 | Yes |
2986 | 2398 | 1199.0 | 63.07 | 31.5 | Imaging cognition II: An empirical review of 275 PET and fMRI studies. | R Cabeza, L Nyberg | J Cogn Neurosci | 2000 | 10769304 | No |
2987 | 1199 | 1199.0 | 32.22 | 32.2 | The emotional dog and its rational tail: a social intuitionist approach to moral judgment. | J Haidt | Psychol Rev | 2001 | 11699120 | Yes |
2988 | 1199 | 1199.0 | 50.44 | 50.4 | The use of the Center for Epidemiologic Studies Depression Scale in adolescents and young adults. | L S Radloff | J Youth Adolesc | 1991 | 24265004 | Yes |
2989 | 2397 | 1198.5 | 61.65 | 30.8 | Humans integrate visual and haptic information in a statistically optimal fashion. | Marc O Ernst, Martin S Banks | Nature | 2002 | 11807554 | Yes |
2990 | 2397 | 1198.5 | 68.65 | 34.3 | Titanium dioxide nanomaterials: synthesis, properties, modifications, and applications. | Xiaobo Chen, Samuel S Mao | Chem Rev | 2007 | 17590053 | Yes |
2991 | 4793 | 1198.2 | 196.08 | 49.0 | QUAST: quality assessment tool for genome assemblies. | Alexey Gurevich, Vladislav Saveliev, Nikolay Vyahhi, Glenn Tesler | Bioinformatics | 2013 | 23422339 | Yes |
2992 | 1198 | 1198.0 | 40.9 | 40.9 | The deadly quartet. Upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension. | N M Kaplan | Arch Intern Med | 1989 | 2662932 | No |
2993 | 1198 | 1198.0 | 46.82 | 46.8 | Geriatric Depression Scale. | J A Yesavage | Psychopharmacol Bull | 1988 | 3249773 | Yes |
2994 | 1198 | 1198.0 | 61.0 | 61.0 | Rating scales to assess depression in school-aged children. | M Kovacs | Acta Paedopsychiatr | 1981 | 7025571 | Yes |
2995 | 1198 | 1198.0 | 44.74 | 44.7 | The evolving concept of health literacy. | Don Nutbeam | Soc Sci Med | 2008 | 18952344 | Yes |
2996 | 1197 | 1197.0 | 38.36 | 38.4 | The Danish Register of Causes of Death. | Karin Helweg-Larsen | Scand J Public Health | 2011 | 21775346 | Yes |
2997 | 1196 | 1196.0 | 25.91 | 25.9 | An overview of epithelio-mesenchymal transformation. | E D Hay | Acta Anat (Basel) | 1995 | 8714286 | No |
2998 | 2392 | 1196.0 | 47.78 | 23.9 | Of mice and not men: differences between mouse and human immunology. | Javier Mestas, Christopher C W Hughes | J Immunol | 2004 | 14978070 | No |
2999 | 4783 | 1195.8 | 132.09 | 33.0 | Toxic potential of materials at the nanolevel. | Andre Nel, Tian Xia, Lutz Mädler, Ning Li | Science | 2006 | 16456071 | No |
3000 | 1195 | 1195.0 | 31.02 | 31.0 | Q-ball imaging. | David S Tuch | Magn Reson Med | 2004 | 15562495 | Yes |
3001 | 1194 | 1194.0 | 32.92 | 32.9 | Normalization of cell responses in cat striate cortex. | D J Heeger | Vis Neurosci | 1992 | 1504027 | Yes |
3002 | 1194 | 1194.0 | 48.94 | 48.9 | Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). | S Safe | Crit Rev Toxicol | 1990 | 2124811 | No |
3003 | 1194 | 1194.0 | 29.6 | 29.6 | Hereditary cancer, oncogenes, and antioncogenes. | A G Knudson | Cancer Res | 1985 | 2983882 | Yes |
3004 | 1194 | 1194.0 | 27.95 | 27.9 | Matrix proteoglycans: from molecular design to cellular function. | R V Iozzo | Annu Rev Biochem | 1998 | 9759499 | No |
3005 | 3582 | 1194.0 | 73.61 | 24.5 | Toll-like receptors: critical proteins linking innate and acquired immunity. | S Akira, K Takeda, T Kaisho | Nat Immunol | 2001 | 11477402 | No |
3006 | 1193 | 1193.0 | 36.76 | 36.8 | Biosynthesis and metabolism of endothelium-derived nitric oxide. | L J Ignarro | Annu Rev Pharmacol Toxicol | 1990 | 2188578 | No |
3007 | 1193 | 1193.0 | 20.8 | 20.8 | Stem cells: units of development, units of regeneration, and units in evolution. | I L Weissman | Cell | 2000 | 10647940 | No |
3008 | 1193 | 1193.0 | 34.53 | 34.5 | MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship. | Amy E Pasquinelli | Nat Rev Genet | 2012 | 22411466 | No |
3009 | 4769 | 1192.2 | 130.7 | 32.7 | Measurement of the elastic properties and intrinsic strength of monolayer graphene. | Changgu Lee, Xiaoding Wei, Jeffrey W Kysar, James Hone | Science | 2008 | 18635798 | Yes |
3010 | 1192 | 1192.0 | 35.98 | 36.0 | The mysteries of lipoprotein(a). | G Utermann | Science | 1989 | 2530631 | No |
3011 | 1192 | 1192.0 | 33.26 | 33.3 | Papillary and follicular thyroid carcinoma. | M J Schlumberger | N Engl J Med | 1998 | 9445411 | No |
3012 | 2383 | 1191.5 | 49.4 | 24.7 | Sequence logos: a new way to display consensus sequences. | T D Schneider, R M Stephens | Nucleic Acids Res | 1990 | 2172928 | Yes |
3013 | 2383 | 1191.5 | 45.44 | 22.7 | Dynamic instability of microtubule growth. | T Mitchison, M Kirschner | Nature | 1984 | 6504138 | Yes |
3014 | 2383 | 1191.5 | 49.72 | 24.9 | Atherosclerosis. the road ahead. | C K Glass, J L Witztum | Cell | 2001 | 11239408 | No |
3015 | 1191 | 1191.0 | 34.66 | 34.7 | Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes. | W Sieghart | Pharmacol Rev | 1995 | 7568326 | No |
3016 | 1191 | 1191.0 | 32.76 | 32.8 | Diversity of group types, regulation, and function of phospholipase A2. | E A Dennis | J Biol Chem | 1994 | 8175726 | No |
3017 | 1191 | 1191.0 | 28.5 | 28.5 | Metabolism and functions of glutathione in brain. | R Dringen | Prog Neurobiol | 2000 | 10880854 | No |
3018 | 1191 | 1191.0 | 52.81 | 52.8 | The Colorimetric Micro-Determination Of Non-Esterified Fatty Acids In Plasma. | W G Duncombe | Clin Chim Acta | 1964 | 14122498 | Yes |
3019 | 2382 | 1191.0 | 49.0 | 24.5 | NF-kappaB: linking inflammation and immunity to cancer development and progression. | Michael Karin, Florian R Greten | Nat Rev Immunol | 2005 | 16175180 | No |
3020 | 1191 | 1191.0 | 30.5 | 30.5 | Physiology and pathophysiology of purinergic neurotransmission. | Geoffrey Burnstock | Physiol Rev | 2007 | 17429044 | No |
3021 | 2381 | 1190.5 | 57.93 | 29.0 | Heat-shock proteins, molecular chaperones, and the stress response: evolutionary and ecological physiology. | M E Feder, G E Hofmann | Annu Rev Physiol | 1999 | 10099689 | No |
3022 | 1190 | 1190.0 | 21.37 | 21.4 | Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes. | D Hanahan | Nature | 1985 | 2986015 | Yes |
3023 | 1189 | 1189.0 | 30.15 | 30.1 | Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. | G Boden | Diabetes | 1997 | 8971073 | No |
3024 | 1189 | 1189.0 | 19.39 | 19.4 | Themes and variations on ubiquitylation. | A M Weissman | Nat Rev Mol Cell Biol | 2001 | 11265246 | No |
3025 | 1189 | 1189.0 | 33.86 | 33.9 | Atomic layer deposition: an overview. | Steven M George | Chem Rev | 2010 | 19947596 | Yes |
3026 | 19021 | 1188.8 | 545.17 | 34.1 | New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). | E A Eisenhauer, P Therasse, J Bogaerts, L H Schwartz, D Sargent, R Ford, J Dancey, S Arbuck, S Gwyther, M Mooney, L Rubinstein, L Shankar, L Dodd, R Kaplan, D Lacombe, J Verweij | Eur J Cancer | 2009 | 19097774 | No |
3027 | 10694 | 1188.2 | 354.02 | 39.3 | A novel potent vasoconstrictor peptide produced by vascular endothelial cells. | M Yanagisawa, H Kurihara, S Kimura, Y Tomobe, M Kobayashi, Y Mitsui, Y Yazaki, K Goto, T Masaki | Nature | 1988 | 2451132 | Yes |
3028 | 4753 | 1188.2 | 136.99 | 34.2 | Place navigation impaired in rats with hippocampal lesions. | R G Morris, P Garrud, J N Rawlins, J O'Keefe | Nature | 1982 | 7088155 | Yes |
3029 | 1188 | 1188.0 | 34.88 | 34.9 | The structure of common mental disorders. | R F Krueger | Arch Gen Psychiatry | 1999 | 10530634 | Yes |
3030 | 2376 | 1188.0 | 44.14 | 22.1 | Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. | C Li, W H Wong | Proc Natl Acad Sci U S A | 2001 | 11134512 | Yes |
3031 | 1188 | 1188.0 | 24.1 | 24.1 | Evo-devo and an expanding evolutionary synthesis: a genetic theory of morphological evolution. | Sean B Carroll | Cell | 2008 | 18614008 | Yes |
3032 | 1188 | 1188.0 | 29.83 | 29.8 | Molecular genetics of colorectal cancer. | Eric R Fearon | Annu Rev Pathol | 2011 | 21090969 | No |
3033 | 5936 | 1187.2 | 141.1 | 28.2 | Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. | T R Mosmann, H Cherwinski, M W Bond, M A Giedlin, R L Coffman | J Immunol | 1986 | 2419430 | Yes |
3034 | 2374 | 1187.0 | 111.91 | 56.0 | Simultaneous single isotope radioenzymatic assay of plasma norepinephrine, epinephrine and dopamine. | J D Peuler, G A Johnson | Life Sci | 1977 | 904439 | Yes |
3035 | 1187 | 1187.0 | 23.73 | 23.7 | Protein tyrosine phosphatases: from genes, to function, to disease. | Nicholas K Tonks | Nat Rev Mol Cell Biol | 2006 | 17057753 | No |
3036 | 2374 | 1187.0 | 69.49 | 34.7 | Natural products as sources of new drugs over the last 25 years. | David J Newman, Gordon M Cragg | J Nat Prod | 2007 | 17309302 | No |
3037 | 2373 | 1186.5 | 84.07 | 42.0 | Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells. | A Fabiato, F Fabiato | J Physiol (Paris) | 1979 | 533865 | Yes |
3038 | 2372 | 1186.0 | 61.24 | 30.6 | Statistical tests of neutrality of mutations. | Y X Fu, W H Li | Genetics | 1993 | 8454210 | Yes |
3039 | 1186 | 1186.0 | 23.53 | 23.5 | Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. | Harold F Dvorak | J Clin Oncol | 2002 | 12409337 | No |
3040 | 1186 | 1186.0 | 23.63 | 23.6 | Up on the tightrope: natural killer cell activation and inhibition. | Lewis L Lanier | Nat Immunol | 2008 | 18425106 | No |
3041 | 4744 | 1186.0 | 132.77 | 33.2 | AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. | Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan | Nat Cell Biol | 2011 | 21258367 | Yes |
3042 | 2371 | 1185.5 | 71.75 | 35.9 | Plasmonics for improved photovoltaic devices. | Harry A Atwater, Albert Polman | Nat Mater | 2010 | 20168344 | Yes |
3043 | 1185 | 1185.0 | 52.07 | 52.1 | Presynaptic regulation of the release of catecholamines. | S Z Langer | Pharmacol Rev | 1980 | 6267618 | Yes |
3044 | 5925 | 1185.0 | 198.64 | 39.7 | Posttraumatic stress disorder in the National Comorbidity Survey. | R C Kessler, A Sonnega, E Bromet, M Hughes, C B Nelson | Arch Gen Psychiatry | 1995 | 7492257 | Yes |
3045 | 1185 | 1185.0 | 30.08 | 30.1 | Disorders of iron metabolism. | N C Andrews | N Engl J Med | 1999 | 10607817 | No |
3046 | 1185 | 1185.0 | 23.18 | 23.2 | A microRNA as a translational repressor of APETALA2 in Arabidopsis flower development. | Xuemei Chen | Science | 2004 | 12893888 | Yes |
3047 | 16584 | 1184.6 | 353.63 | 25.3 | Crystallography & NMR system: A new software suite for macromolecular structure determination. | A T Brünger, P D Adams, G M Clore, W L DeLano, P Gros, R W Grosse-Kunstleve, J S Jiang, J Kuszewski, M Nilges, N S Pannu, R J Read, L M Rice, T Simonson, G L Warren | Acta Crystallogr D Biol Crystallogr | 1998 | 9757107 | Yes |
3048 | 3552 | 1184.0 | 102.32 | 34.1 | The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. | G Blessed, B E Tomlinson, M Roth | Br J Psychiatry | 1968 | 5662937 | Yes |
3049 | 2368 | 1184.0 | 95.11 | 47.6 | Rapid procedure for detection and isolation of large and small plasmids. | C I Kado, S T Liu | J Bacteriol | 1981 | 7009583 | Yes |
3050 | 1184 | 1184.0 | 36.61 | 36.6 | Peritonectomy procedures. | P H Sugarbaker | Ann Surg | 1995 | 7826158 | Yes |
3051 | 1184 | 1184.0 | 41.64 | 41.6 | Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes. | M A Lemp | CLAO J | 1995 | 8565190 | No |
3052 | 1184 | 1184.0 | 0.0 | 0.0 | Histological demonstration of mucin after periodic acid. | J F A McMANUS | Nature | 1946 | 20995486 | Yes |
3053 | 3551 | 1183.7 | 72.03 | 24.0 | Cellular survival: a play in three Akts. | S R Datta, A Brunet, M E Greenberg | Genes Dev | 1999 | 10579998 | No |
3054 | 2366 | 1183.0 | 65.27 | 32.6 | Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. | R G Phillips, J E LeDoux | Behav Neurosci | 1992 | 1590953 | Yes |
3055 | 1183 | 1183.0 | 26.23 | 26.2 | The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression. | S J Collins | Blood | 1987 | 3311197 | No |
3056 | 1183 | 1183.0 | 26.82 | 26.8 | Hybridization of denatured RNA transferred or dotted nitrocellulose paper. | P S Thomas | Methods Enzymol | 1983 | 6194404 | Yes |
3057 | 1183 | 1183.0 | 25.71 | 25.7 | Simple model of spiking neurons. | E M Izhikevich | IEEE Trans Neural Netw | 2003 | 18244602 | Yes |
3058 | 2365 | 1182.5 | 30.23 | 15.1 | Studies of marine planktonic diatoms. I. Cyclotella nana Hustedt, and Detonula confervacea (cleve) Gran. | R R Guillard, J H Ryther | Can J Microbiol | 1962 | 13902807 | Yes |
3059 | 5912 | 1182.4 | 288.69 | 57.7 | Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. | N Bellamy, W W Buchanan, C H Goldsmith, J Campbell, L W Stitt | J Rheumatol | 1988 | 3068365 | Yes |
3060 | 1182 | 1182.0 | 36.24 | 36.2 | The somatic marker hypothesis and the possible functions of the prefrontal cortex. | A R Damasio | Philos Trans R Soc Lond B Biol Sci | 1996 | 8941953 | No |
3061 | 1182 | 1182.0 | 20.71 | 20.7 | Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig. | G D Winter | Nature | 1962 | 14007593 | Yes |
3062 | 1182 | 1182.0 | 31.05 | 31.1 | Bacteroides: the good, the bad, and the nitty-gritty. | Hannah M Wexler | Clin Microbiol Rev | 2007 | 17934076 | No |
3063 | 5908 | 1181.6 | 219.02 | 43.8 | DNA primers for amplification of mitochondrial cytochrome c oxidase subunit I from diverse metazoan invertebrates. | O Folmer, M Black, W Hoeh, R Lutz, R Vrijenhoek | Mol Mar Biol Biotechnol | 1994 | 7881515 | Yes |
3064 | 2363 | 1181.5 | 88.16 | 44.1 | Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. | H Esterbauer, K H Cheeseman | Methods Enzymol | 1990 | 2233308 | Yes |
3065 | 2363 | 1181.5 | 48.51 | 24.3 | The mammalian unfolded protein response. | Martin Schröder, Randal J Kaufman | Annu Rev Biochem | 2005 | 15952902 | No |
3066 | 4726 | 1181.5 | 147.95 | 37.0 | Epidemiology and causes of preterm birth. | Robert L Goldenberg, Jennifer F Culhane, Jay D Iams, Roberto Romero | Lancet | 2008 | 18177778 | No |
3067 | 2363 | 1181.5 | 65.85 | 32.9 | New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. | Jonathan B Baell, Georgina A Holloway | J Med Chem | 2010 | 20131845 | Yes |
3068 | 1181 | 1181.0 | 45.2 | 45.2 | Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes. | H V Gelboin | Physiol Rev | 1980 | 7001511 | No |
3069 | 1181 | 1181.0 | 38.84 | 38.8 | Checklists for improving rigour in qualitative research: a case of the tail wagging the dog? | R S Barbour | BMJ | 2001 | 11337448 | No |
3070 | 1181 | 1181.0 | 0.0 | 0.0 | Voluntary strength and fatigue. | P A Merton | J Physiol | 1954 | 13152698 | Yes |
3071 | 1181 | 1181.0 | 54.57 | 54.6 | Salience processing and insular cortical function and dysfunction. | Lucina Q Uddin | Nat Rev Neurosci | 2015 | 25406711 | No |
3072 | 1180 | 1180.0 | 65.5 | 65.5 | Nontuberculous mycobacteria and associated diseases. | E Wolinsky | Am Rev Respir Dis | 1979 | 369415 | No |
3073 | 2360 | 1180.0 | 102.14 | 51.1 | Numerical index of the discriminatory ability of typing systems: an application of Simpson's index of diversity. | P R Hunter, M A Gaston | J Clin Microbiol | 1988 | 3069867 | Yes |
3074 | 1180 | 1180.0 | 32.39 | 32.4 | The stress response to trauma and surgery. | J P Desborough | Br J Anaesth | 2000 | 10927999 | No |
3075 | 1180 | 1180.0 | 43.89 | 43.9 | Energy metabolism in the liver. | Liangyou Rui | Compr Physiol | 2014 | 24692138 | No |
3076 | 1179 | 1179.0 | 34.45 | 34.5 | A human model of gastric carcinogenesis. | P Correa | Cancer Res | 1988 | 3288329 | No |
3077 | 1179 | 1179.0 | 38.78 | 38.8 | Interleukin-1 and the pathogenesis of the acute-phase response. | C A Dinarello | N Engl J Med | 1984 | 6208485 | No |
3078 | 1179 | 1179.0 | 73.02 | 73.0 | Impingement lesions. | C S Neer | Clin Orthop Relat Res | 1983 | 6825348 | Yes |
3079 | 1179 | 1179.0 | 25.43 | 25.4 | The myofibroblast in wound healing and fibrocontractive diseases. | G Gabbiani | J Pathol | 2003 | 12845617 | No |
3080 | 1179 | 1179.0 | 34.03 | 34.0 | The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin. | R G Pertwee | Br J Pharmacol | 2008 | 17828291 | No |
3081 | 1179 | 1179.0 | 58.67 | 58.7 | The new statistics: why and how. | Geoff Cumming | Psychol Sci | 2014 | 24220629 | Yes |
3082 | 2357 | 1178.5 | 68.18 | 34.1 | The low-density lipoprotein pathway and its relation to atherosclerosis. | J L Goldstein, M S Brown | Annu Rev Biochem | 1977 | 197883 | No |
3083 | 2357 | 1178.5 | 52.42 | 26.2 | Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. | Jing Yang, Robert A Weinberg | Dev Cell | 2008 | 18539112 | No |
3084 | 10605 | 1178.3 | 274.05 | 30.5 | MolProbity: all-atom structure validation for macromolecular crystallography. | Vincent B Chen, W Bryan Arendall, Jeffrey J Headd, Daniel A Keedy, Robert M Immormino, Gary J Kapral, Laura W Murray, Jane S Richardson, David C Richardson | Acta Crystallogr D Biol Crystallogr | 2010 | 20057044 | Yes |
3085 | 5891 | 1178.2 | 190.79 | 38.2 | Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. | D Steinberg, S Parthasarathy, T E Carew, J C Khoo, J L Witztum | N Engl J Med | 1989 | 2648148 | No |
3086 | 1178 | 1178.0 | 25.78 | 25.8 | How neutrophils kill microbes. | Anthony W Segal | Annu Rev Immunol | 2005 | 15771570 | No |
3087 | 1178 | 1178.0 | 0.0 | 0.0 | Immunity to homologous grafted skin; the fate of skin homografts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye. | P B Medawar | Br J Exp Pathol | 1948 | 18865105 | Yes |
3088 | 1178 | 1178.0 | 28.36 | 28.4 | Targeting DNA topoisomerase II in cancer chemotherapy. | John L Nitiss | Nat Rev Cancer | 2009 | 19377506 | No |
3089 | 1178 | 1178.0 | 46.09 | 46.1 | A review and synthesis of the first 20 years of PET and fMRI studies of heard speech, spoken language and reading. | Cathy J Price | Neuroimage | 2012 | 22584224 | No |
3090 | 2355 | 1177.5 | 50.77 | 25.4 | Lymphocyte homing and homeostasis. | E C Butcher, L J Picker | Science | 1996 | 8600538 | No |
3091 | 2355 | 1177.5 | 48.58 | 24.3 | Toll-like receptors in the induction of the innate immune response. | A Aderem, R J Ulevitch | Nature | 2000 | 10963608 | No |
3092 | 8241 | 1177.3 | 162.65 | 23.2 | Exploration, normalization, and summaries of high density oligonucleotide array probe level data. | Rafael A Irizarry, Bridget Hobbs, Francois Collin, Yasmin D Beazer-Barclay, Kristen J Antonellis, Uwe Scherf, Terence P Speed | Biostatistics | 2003 | 12925520 | Yes |
3093 | 1177 | 1177.0 | 34.55 | 34.5 | Analyzing the mosaic structure of genes. | J M Smith | J Mol Evol | 1992 | 1556748 | No |
3094 | 1177 | 1177.0 | 28.11 | 28.1 | A tension-based theory of morphogenesis and compact wiring in the central nervous system. | D C Van Essen | Nature | 1997 | 9002514 | Yes |
3095 | 1177 | 1177.0 | 47.11 | 47.1 | The anatomy of stages of change. | A Bandura | Am J Health Promot | 1997 | 10170438 | No |
3096 | 2354 | 1177.0 | 56.37 | 28.2 | Predictive coding in the visual cortex: a functional interpretation of some extra-classical receptive-field effects. | R P Rao, D H Ballard | Nat Neurosci | 1999 | 10195184 | Yes |
3097 | 3531 | 1177.0 | 90.67 | 30.2 | Methods in mammalian autophagy research. | Noboru Mizushima, Tamotsu Yoshimori, Beth Levine | Cell | 2010 | 20144757 | Yes |
3098 | 2353 | 1176.5 | 76.75 | 38.4 | Quantitative determination of serum triglycerides by the use of enzymes. | G Bucolo, H David | Clin Chem | 1973 | 4703655 | Yes |
3099 | 4706 | 1176.5 | 105.36 | 26.3 | Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. | J E Walker, M Saraste, M J Runswick, N J Gay | EMBO J | 1982 | 6329717 | Yes |
3100 | 1176 | 1176.0 | 40.56 | 40.6 | An approach for the treatment of penile carcinoma. | R M Cabanas | Cancer | 1977 | 837331 | Yes |
3101 | 1176 | 1176.0 | 37.93 | 37.9 | Agents that increase the permeability of the outer membrane. | M Vaara | Microbiol Rev | 1992 | 1406489 | No |
3102 | 2352 | 1176.0 | 76.34 | 38.2 | Physiological parameters in laboratory animals and humans. | B Davies, T Morris | Pharm Res | 1993 | 8378254 | No |
3103 | 1176 | 1176.0 | 30.54 | 30.5 | The neurobiology of stress: from serendipity to clinical relevance. | B S McEwen | Brain Res | 2000 | 11119695 | No |
3104 | 1176 | 1176.0 | 39.91 | 39.9 | Volumetric modulated arc therapy: IMRT in a single gantry arc. | Karl Otto | Med Phys | 2008 | 18293586 | Yes |
3105 | 3527 | 1175.7 | 163.23 | 54.4 | Cross-cultural adaptation of health-related quality of life measures: literature review and proposed guidelines. | F Guillemin, C Bombardier, D Beaton | J Clin Epidemiol | 1993 | 8263569 | No |
3106 | 2351 | 1175.5 | 61.57 | 30.8 | The ubiquitin code. | David Komander, Michael Rape | Annu Rev Biochem | 2012 | 22524316 | No |
3107 | 2350 | 1175.0 | 201.83 | 100.9 | Radiological demarcation of cemented sockets in total hip replacement. | J G DeLee, J Charnley | Clin Orthop Relat Res | 1976 | 991504 | Yes |
3108 | 1175 | 1175.0 | 24.3 | 24.3 | Microsatellites: simple sequences with complex evolution. | Hans Ellegren | Nat Rev Genet | 2004 | 15153996 | No |
3109 | 2349 | 1174.5 | 42.4 | 21.2 | Hedgehog signaling in animal development: paradigms and principles. | P W Ingham, A P McMahon | Genes Dev | 2001 | 11731473 | No |
3110 | 1174 | 1174.0 | 26.14 | 26.1 | Cadherins: a molecular family important in selective cell-cell adhesion. | M Takeichi | Annu Rev Biochem | 1990 | 2197976 | No |
3111 | 2348 | 1174.0 | 45.97 | 23.0 | Multiple nuclear factors interact with the immunoglobulin enhancer sequences. | R Sen, D Baltimore | Cell | 1986 | 3091258 | Yes |
3112 | 1174 | 1174.0 | 32.32 | 32.3 | The induction of pain: an integrative review. | M J Millan | Prog Neurobiol | 1999 | 9987804 | No |
3113 | 1174 | 1174.0 | 0.0 | 0.0 | A production of amino acids under possible primitive earth conditions. | S L Miller | Science | 1953 | 13056598 | Yes |
3114 | 2347 | 1173.5 | 72.15 | 36.1 | Theoretical studies of enzymic reactions: dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme. | A Warshel, M Levitt | J Mol Biol | 1976 | 985660 | Yes |
3115 | 2347 | 1173.5 | 52.72 | 26.4 | Adaptive protein evolution at the Adh locus in Drosophila. | J H McDonald, M Kreitman | Nature | 1991 | 1904993 | Yes |
3116 | 3520 | 1173.3 | 73.76 | 24.6 | Computer visualization of three-dimensional image data using IMOD. | J R Kremer, D N Mastronarde, J R McIntosh | J Struct Biol | 1996 | 8742726 | Yes |
3117 | 1173 | 1173.0 | 45.59 | 45.6 | Freezing of living cells: mechanisms and implications. | P Mazur | Am J Physiol | 1984 | 6383068 | No |
3118 | 1173 | 1173.0 | 38.9 | 38.9 | Enhancing the quality and credibility of qualitative analysis. | M Q Patton | Health Serv Res | 1999 | 10591279 | No |
3119 | 2346 | 1173.0 | 66.42 | 33.2 | Heterogeneous photocatalyst materials for water splitting. | Akihiko Kudo, Yugo Miseki | Chem Soc Rev | 2009 | 19088977 | Yes |
3120 | 3518 | 1172.7 | 90.12 | 30.0 | Towards a natural system of organisms: proposal for the domains Archaea, Bacteria, and Eucarya. | C R Woese, O Kandler, M L Wheelis | Proc Natl Acad Sci U S A | 1990 | 2112744 | Yes |
3121 | 7036 | 1172.7 | 199.97 | 33.3 | Genome engineering using the CRISPR-Cas9 system. | F Ann Ran, Patrick D Hsu, Jason Wright, Vineeta Agarwala, David A Scott, Feng Zhang | Nat Protoc | 2013 | 24157548 | Yes |
3122 | 3517 | 1172.3 | 88.04 | 29.3 | Use and abuse of HOMA modeling. | Tara M Wallace, Jonathan C Levy, David R Matthews | Diabetes Care | 2004 | 15161807 | No |
3123 | 2344 | 1172.0 | 73.29 | 36.6 | Antiseptics and disinfectants: activity, action, and resistance. | G McDonnell, A D Russell | Clin Microbiol Rev | 1999 | 9880479 | No |
3124 | 1172 | 1172.0 | 24.13 | 24.1 | Apoptosis in neurodegenerative disorders. | M P Mattson | Nat Rev Mol Cell Biol | 2000 | 11253364 | No |
3125 | 4688 | 1172.0 | 132.71 | 33.2 | Biological identifications through DNA barcodes. | Paul D N Hebert, Alina Cywinska, Shelley L Ball, Jeremy R deWaard | Proc Biol Sci | 2003 | 12614582 | Yes |
3126 | 2343 | 1171.5 | 74.27 | 37.1 | Solubilization of membranes by detergents. | A Helenius, K Simons | Biochim Biophys Acta | 1975 | 1091302 | No |
3127 | 1171 | 1171.0 | 30.74 | 30.7 | Pathogenesis of dengue: challenges to molecular biology. | S B Halstead | Science | 1988 | 3277268 | No |
3128 | 2341 | 1170.5 | 71.94 | 36.0 | bold: The Barcode of Life Data System (http://www.barcodinglife.org). | Sujeevan Ratnasingham, Paul D N Hebert | Mol Ecol Notes | 2007 | 18784790 | Yes |
3129 | 3510 | 1170.0 | 70.5 | 23.5 | Predicting coiled coils from protein sequences. | A Lupas, M Van Dyke, J Stock | Science | 1991 | 2031185 | Yes |
3130 | 1170 | 1170.0 | 21.84 | 21.8 | Shrinkage necrosis: a distinct mode of cellular death. | J F Kerr | J Pathol | 1971 | 4108566 | Yes |
3131 | 1170 | 1170.0 | 106.27 | 106.3 | The analysis of errors in orthodontic measurements. | W J Houston | Am J Orthod | 1983 | 6573846 | Yes |
3132 | 3510 | 1170.0 | 116.8 | 38.9 | Hepatocellular carcinoma. | Alejandro Forner, Josep M Llovet, Jordi Bruix | Lancet | 2012 | 22353262 | No |
3133 | 1170 | 1170.0 | 44.88 | 44.9 | The biogenesis and emerging roles of circular RNAs. | Ling-Ling Chen | Nat Rev Mol Cell Biol | 2016 | 26908011 | Yes |
3134 | 2339 | 1169.5 | 92.16 | 46.1 | Kraken: ultrafast metagenomic sequence classification using exact alignments. | Derrick E Wood, Steven L Salzberg | Genome Biol | 2014 | 24580807 | Yes |
3135 | 11693 | 1169.3 | 424.5 | 42.5 | The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. | Alessandro Liberati, Douglas G Altman, Jennifer Tetzlaff, Cynthia Mulrow, Peter C Gøtzsche, John P A Ioannidis, Mike Clarke, P J Devereaux, Jos Kleijnen, David Moher | BMJ | 2009 | 19622552 | No |
3136 | 2338 | 1169.0 | 36.81 | 18.4 | Theoretical aspects of DNA-protein interactions: co-operative and non-co-operative binding of large ligands to a one-dimensional homogeneous lattice. | J D McGhee, P H von Hippel | J Mol Biol | 1974 | 4416620 | Yes |
3137 | 1169 | 1169.0 | 31.35 | 31.4 | Core affect and the psychological construction of emotion. | James A Russell | Psychol Rev | 2003 | 12529060 | No |
3138 | 1169 | 1169.0 | 22.81 | 22.8 | Telomeres and human disease: ageing, cancer and beyond. | Maria A Blasco | Nat Rev Genet | 2005 | 16136653 | No |
3139 | 3507 | 1169.0 | 84.79 | 28.3 | Astrocyte-endothelial interactions at the blood-brain barrier. | N Joan Abbott, Lars Rönnbäck, Elisabeth Hansson | Nat Rev Neurosci | 2006 | 16371949 | No |
3140 | 2337 | 1168.5 | 76.62 | 38.3 | Efficacy of the Theory of Planned Behaviour: a meta-analytic review. | C J Armitage, M Conner | Br J Soc Psychol | 2001 | 11795063 | Yes |
3141 | 1168 | 1168.0 | 30.15 | 30.1 | 6-Hydroxy-dopamine induced degeneration of central monoamine neurons. | U Ungerstedt | Eur J Pharmacol | 1968 | 5718510 | Yes |
3142 | 1168 | 1168.0 | 34.86 | 34.9 | Low-molecular-weight heparins. | J I Weitz | N Engl J Med | 1997 | 9278467 | No |
3143 | 1168 | 1168.0 | 0.0 | 0.0 | A chemical method for the determination of oestriol, oestrone and oestradiol in human urine. | J B Brown | Biochem J | 1955 | 14389222 | Yes |
3144 | 1168 | 1168.0 | 45.97 | 46.0 | Comments on 'KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease'. | Konrad M Andrassy | Kidney Int | 2013 | 23989362 | Yes |
3145 | 1168 | 1168.0 | 56.18 | 56.2 | When to use the Bonferroni correction. | Richard A Armstrong | Ophthalmic Physiol Opt | 2014 | 24697967 | No |
3146 | 2335 | 1167.5 | 70.85 | 35.4 | Stochastic relaxation, gibbs distributions, and the bayesian restoration of images. | S Geman, D Geman | IEEE Trans Pattern Anal Mach Intell | 1984 | 22499653 | Yes |
3147 | 1167 | 1167.0 | 31.3 | 31.3 | Presynaptic regulation of catecholamine release. | S Z Langer | Biochem Pharmacol | 1974 | 4617579 | No |
3148 | 1167 | 1167.0 | 0.0 | 0.0 | A simple method of increasing the adhesion of acrylic filling materials to enamel surfaces. | M G Buonocore | J Dent Res | 1955 | 13271655 | Yes |
3149 | 1167 | 1167.0 | 0.0 | 0.0 | The cytoarchitectonic organization of the spinal cord in the cat. | B Rexed | J Comp Neurol | 1952 | 14946260 | Yes |
3150 | 10502 | 1166.9 | 270.84 | 30.1 | Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. | Cole Trapnell, Brian A Williams, Geo Pertea, Ali Mortazavi, Gordon Kwan, Marijke J van Baren, Steven L Salzberg, Barbara J Wold, Lior Pachter | Nat Biotechnol | 2010 | 20436464 | Yes |
3151 | 4667 | 1166.8 | 124.3 | 31.1 | Organometal halide perovskites as visible-light sensitizers for photovoltaic cells. | Akihiro Kojima, Kenjiro Teshima, Yasuo Shirai, Tsutomu Miyasaka | J Am Chem Soc | 2009 | 19366264 | Yes |
3152 | 4666 | 1166.5 | 108.44 | 27.1 | Base-calling of automated sequencer traces using phred. I. Accuracy assessment. | B Ewing, L Hillier, M C Wendl, P Green | Genome Res | 1998 | 9521921 | Yes |
3153 | 2333 | 1166.5 | 95.82 | 47.9 | Systematic review of the health benefits of physical activity and fitness in school-aged children and youth. | Ian Janssen, Allana G Leblanc | Int J Behav Nutr Phys Act | 2010 | 20459784 | Yes |
3154 | 3499 | 1166.3 | 78.75 | 26.2 | Molecular weight estimation of polypeptide chains by electrophoresis in SDS-polyacrylamide gels. | A L Shapiro, E Viñuela, J V Maizel | Biochem Biophys Res Commun | 1967 | 4861258 | Yes |
3155 | 1166 | 1166.0 | 33.27 | 33.3 | What is synergy? | M C Berenbaum | Pharmacol Rev | 1989 | 2692037 | No |
3156 | 1166 | 1166.0 | 35.68 | 35.7 | Context, time, and memory retrieval in the interference paradigms of Pavlovian learning. | M E Bouton | Psychol Bull | 1993 | 8346330 | No |
3157 | 4664 | 1166.0 | 90.09 | 22.5 | Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. | L Alexopoulou, A C Holt, R Medzhitov, R A Flavell | Nature | 2001 | 11607032 | Yes |
3158 | 2331 | 1165.5 | 69.44 | 34.7 | Software survey: VOSviewer, a computer program for bibliometric mapping. | Nees Jan van Eck, Ludo Waltman | Scientometrics | 2010 | 20585380 | Yes |
3159 | 1165 | 1165.0 | 35.66 | 35.7 | MOPAC: a semiempirical molecular orbital program. | J J Stewart | J Comput Aided Mol Des | 1990 | 2197373 | No |
3160 | 1165 | 1165.0 | 22.1 | 22.1 | Contingent genetic regulatory events in T lymphocyte activation. | G R Crabtree | Science | 1989 | 2783497 | Yes |
3161 | 1165 | 1165.0 | 11.53 | 11.5 | Pathologic anatomy of the pancreas in juvenile diabetes mellitus. | W Gepts | Diabetes | 1965 | 5318831 | Yes |
3162 | 1165 | 1165.0 | 31.72 | 31.7 | Pharmacology of cannabinoid CB1 and CB2 receptors. | R G Pertwee | Pharmacol Ther | 1997 | 9336020 | No |
3163 | 2330 | 1165.0 | 49.22 | 24.6 | Functions of lipid rafts in biological membranes. | D A Brown, E London | Annu Rev Cell Dev Biol | 1998 | 9891780 | No |
3164 | 4658 | 1164.5 | 175.3 | 43.8 | Near-optimal probabilistic RNA-seq quantification. | Nicolas L Bray, Harold Pimentel, Páll Melsted, Lior Pachter | Nat Biotechnol | 2016 | 27043002 | Yes |
3165 | 1164 | 1164.0 | 22.02 | 22.0 | Microarray data normalization and transformation. | John Quackenbush | Nat Genet | 2002 | 12454644 | No |
3166 | 1164 | 1164.0 | 35.35 | 35.4 | Platelet-rich plasma: evidence to support its use. | Robert E Marx | J Oral Maxillofac Surg | 2004 | 15085519 | No |
3167 | 1164 | 1164.0 | 37.66 | 37.7 | On the law of effect. | R J Herrnstein | J Exp Anal Behav | 1970 | 16811440 | Yes |
3168 | 3491 | 1163.7 | 138.78 | 46.3 | Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves. | A DeLean, P J Munson, D Rodbard | Am J Physiol | 1978 | 686171 | Yes |
3169 | 2327 | 1163.5 | 79.72 | 39.9 | The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis. | G P Chrousos, P W Gold | JAMA | 1992 | 1538563 | No |
3170 | 6981 | 1163.5 | 237.18 | 39.5 | The occurrence of sleep-disordered breathing among middle-aged adults. | T Young, M Palta, J Dempsey, J Skatrud, S Weber, S Badr | N Engl J Med | 1993 | 8464434 | Yes |
3171 | 2327 | 1163.5 | 63.02 | 31.5 | A new local density functional for main-group thermochemistry, transition metal bonding, thermochemical kinetics, and noncovalent interactions. | Yan Zhao, Donald G Truhlar | J Chem Phys | 2006 | 17129083 | Yes |
3172 | 2327 | 1163.5 | 84.07 | 42.0 | Severe sepsis and septic shock. | Derek C Angus, Tom van der Poll | N Engl J Med | 2013 | 23984731 | No |
3173 | 1163 | 1163.0 | 41.98 | 42.0 | The case for motivated reasoning. | Z Kunda | Psychol Bull | 1990 | 2270237 | No |
3174 | 1163 | 1163.0 | 36.67 | 36.7 | Molecular biology of steroid hormone synthesis. | W L Miller | Endocr Rev | 1988 | 3061784 | No |
3175 | 1163 | 1163.0 | 34.27 | 34.3 | Determinants of tumor blood flow: a review. | R K Jain | Cancer Res | 1988 | 3282647 | No |
3176 | 1163 | 1163.0 | 34.75 | 34.8 | Effect of anoxia on ion distribution in the brain. | A J Hansen | Physiol Rev | 1985 | 3880896 | No |
3177 | 1163 | 1163.0 | 23.73 | 23.7 | Biogenic amines and the states of sleep. | M Jouvet | Science | 1969 | 4303225 | No |
3178 | 1163 | 1163.0 | 51.2 | 51.2 | Preliminary Trial Of Carisoprodol In Multiple Sclerosis. | B Ashworth | Practitioner | 1964 | 14143329 | Yes |
3179 | 3489 | 1163.0 | 76.96 | 25.7 | Hepatocellular carcinoma. | Josep M Llovet, Andrew Burroughs, Jordi Bruix | Lancet | 2003 | 14667750 | No |
3180 | 1162 | 1162.0 | 26.78 | 26.8 | Neurons with graded response have collective computational properties like those of two-state neurons. | J J Hopfield | Proc Natl Acad Sci U S A | 1984 | 6587342 | Yes |
3181 | 1162 | 1162.0 | 39.22 | 39.2 | beta-Lactamases in laboratory and clinical resistance. | D M Livermore | Clin Microbiol Rev | 1995 | 8665470 | No |
3182 | 1162 | 1162.0 | 22.19 | 22.2 | The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities. | Y Yarden | Eur J Cancer | 2001 | 11597398 | No |
3183 | 1162 | 1162.0 | 31.3 | 31.3 | Production and scavenging of reactive oxygen species in chloroplasts and their functions. | Kozi Asada | Plant Physiol | 2006 | 16760493 | Yes |
3184 | 2324 | 1162.0 | 50.38 | 25.2 | Blinded by the Light: The Growing Complexity of p53. | Karen H Vousden, Carol Prives | Cell | 2009 | 19410540 | No |
3185 | 3485 | 1161.7 | 118.74 | 39.6 | The 'Trier Social Stress Test'--a tool for investigating psychobiological stress responses in a laboratory setting. | C Kirschbaum, K M Pirke, D H Hellhammer | Neuropsychobiology | 1993 | 8255414 | Yes |
3186 | 2323 | 1161.5 | 47.53 | 23.8 | Learning the parts of objects by non-negative matrix factorization. | D D Lee, H S Seung | Nature | 1999 | 10548103 | Yes |
3187 | 2323 | 1161.5 | 53.64 | 26.8 | Regulation of wound healing by growth factors and cytokines. | Sabine Werner, Richard Grose | Physiol Rev | 2003 | 12843410 | No |
3188 | 1161 | 1161.0 | 17.5 | 17.5 | The Nature Of Herpes Zoster: A Long-Term Study And A New Hypothesis. | R E Hope-Simpson | Proc R Soc Med | 1965 | 14267505 | Yes |
3189 | 1161 | 1161.0 | 27.84 | 27.8 | Context and behavioral processes in extinction. | Mark E Bouton | Learn Mem | 2004 | 15466298 | No |
3190 | 1161 | 1161.0 | 26.65 | 26.6 | Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms. | William C Aird | Circ Res | 2007 | 17272818 | No |
3191 | 3482 | 1160.7 | 147.22 | 49.1 | Measurement of health status. Ascertaining the minimal clinically important difference. | R Jaeschke, J Singer, G H Guyatt | Control Clin Trials | 1989 | 2691207 | Yes |
3192 | 1160 | 1160.0 | 38.08 | 38.1 | Starting at the beginning: an introduction to coefficient alpha and internal consistency. | David L Streiner | J Pers Assess | 2003 | 12584072 | Yes |
3193 | 1160 | 1160.0 | 30.49 | 30.5 | Epidemiology of women and depression. | Ronald C Kessler | J Affect Disord | 2003 | 12646294 | Yes |
3194 | 1160 | 1160.0 | 23.34 | 23.3 | Liver regeneration: from myth to mechanism. | Rebecca Taub | Nat Rev Mol Cell Biol | 2004 | 15459664 | No |
3195 | 3478 | 1159.3 | 107.6 | 35.9 | Evaluating the public health impact of health promotion interventions: the RE-AIM framework. | R E Glasgow, T M Vogt, S M Boles | Am J Public Health | 1999 | 10474547 | No |
3196 | 1159 | 1159.0 | 35.95 | 36.0 | Strategies of antioxidant defense. | H Sies | Eur J Biochem | 1993 | 7688300 | No |
3197 | 1159 | 1159.0 | 38.61 | 38.6 | Mediators and mechanisms of change in psychotherapy research. | Alan E Kazdin | Annu Rev Clin Psychol | 2007 | 17716046 | No |
3198 | 2317 | 1158.5 | 53.94 | 27.0 | Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival. | Josep M Llovet, Jordi Bruix | Hepatology | 2003 | 12540794 | No |
3199 | 2317 | 1158.5 | 54.11 | 27.1 | Establishing, maintaining and modifying DNA methylation patterns in plants and animals. | Julie A Law, Steven E Jacobsen | Nat Rev Genet | 2010 | 20142834 | No |
3200 | 3475 | 1158.3 | 84.63 | 28.2 | High resolution two-dimensional electrophoresis of basic as well as acidic proteins. | P Z O'Farrell, H M Goodman, P H O'Farrell | Cell | 1977 | 23215 | Yes |
3201 | 1158 | 1158.0 | 22.04 | 22.0 | RNA metabolism in the HeLa cell nucleus. | S Penman | J Mol Biol | 1966 | 5961144 | Yes |
3202 | 1158 | 1158.0 | 25.95 | 25.9 | Effect of carvedilol on outcome after myocardial infarction in patients with left-ventricular dysfunction: the CAPRICORN randomised trial. | H J Dargie | Lancet | 2001 | 11356434 | Yes |
3203 | 1158 | 1158.0 | 52.54 | 52.5 | The problem with the phrase women and minorities: intersectionality-an important theoretical framework for public health. | Lisa Bowleg | Am J Public Health | 2012 | 22594719 | Yes |
3204 | 2315 | 1157.5 | 49.51 | 24.8 | Defining the role of mTOR in cancer. | David A Guertin, David M Sabatini | Cancer Cell | 2007 | 17613433 | No |
3205 | 1157 | 1157.0 | 39.58 | 39.6 | Estimation of the number of nucleotide substitutions when there are strong transition-transversion and G+C-content biases. | K Tamura | Mol Biol Evol | 1992 | 1630306 | Yes |
3206 | 1157 | 1157.0 | 14.77 | 14.8 | Central dogma of molecular biology. | F Crick | Nature | 1970 | 4913914 | No |
3207 | 5781 | 1156.2 | 108.26 | 21.7 | The protein kinase complement of the human genome. | G Manning, D B Whyte, R Martinez, T Hunter, S Sudarsanam | Science | 2002 | 12471243 | No |
3208 | 1156 | 1156.0 | 28.35 | 28.4 | The epidemiologic transition. A theory of the epidemiology of population change. | A R Omran | Milbank Mem Fund Q | 1971 | 5155251 | Yes |
3209 | 1156 | 1156.0 | 50.58 | 50.6 | Coping theory and research: past, present, and future. | R S Lazarus | Psychosom Med | 1993 | 8346332 | No |
3210 | 11551 | 1155.1 | 291.54 | 29.2 | Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. | M Dominici, K Le Blanc, I Mueller, I Slaper-Cortenbach, Fc Marini, Ds Krause, Rj Deans, A Keating, Dj Prockop, Em Horwitz | Cytotherapy | 2006 | 16923606 | Yes |
3211 | 2310 | 1155.0 | 59.78 | 29.9 | Verification of protein structures: patterns of nonbonded atomic interactions. | C Colovos, T O Yeates | Protein Sci | 1993 | 8401235 | Yes |
3212 | 1155 | 1155.0 | 19.88 | 19.9 | Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism. | M S Wold | Annu Rev Biochem | 1997 | 9242902 | No |
3213 | 1155 | 1155.0 | 21.27 | 21.3 | Biological robustness. | Hiroaki Kitano | Nat Rev Genet | 2004 | 15520792 | No |
3214 | 1155 | 1155.0 | 24.38 | 24.4 | The advantages and disadvantages of being polyploid. | Luca Comai | Nat Rev Genet | 2005 | 16304599 | No |
3215 | 1155 | 1155.0 | 0.0 | 0.0 | Observations on the isolated phrenic nerve diaphragm preparation of the rat. | E Bulbring | Br J Pharmacol Chemother | 1946 | 20999334 | Yes |
3216 | 3464 | 1154.7 | 81.7 | 27.2 | Prediction of total genetic value using genome-wide dense marker maps. | T H Meuwissen, B J Hayes, M E Goddard | Genetics | 2001 | 11290733 | Yes |
3217 | 2309 | 1154.5 | 66.88 | 33.4 | Excitatory amino acids as a final common pathway for neurologic disorders. | S A Lipton, P A Rosenberg | N Engl J Med | 1994 | 7905600 | No |
3218 | 5772 | 1154.4 | 163.85 | 32.8 | Quantitative assessment of tactile allodynia in the rat paw. | S R Chaplan, F W Bach, J W Pogrel, J M Chung, T L Yaksh | J Neurosci Methods | 1994 | 7990513 | Yes |
3219 | 1154 | 1154.0 | 12.88 | 12.9 | Autoradiographic and histological studies of postnatal neurogenesis. IV. Cell proliferation and migration in the anterior forebrain, with special reference to persisting neurogenesis in the olfactory bulb. | J Altman | J Comp Neurol | 1969 | 5361244 | Yes |
3220 | 1154 | 1154.0 | 26.76 | 26.8 | Amyloid, the presenilins and Alzheimer's disease. | J Hardy | Trends Neurosci | 1997 | 9106355 | No |
3221 | 2308 | 1154.0 | 72.31 | 36.2 | The reward circuit: linking primate anatomy and human imaging. | Suzanne N Haber, Brian Knutson | Neuropsychopharmacology | 2010 | 19812543 | No |
3222 | 2307 | 1153.5 | 64.38 | 32.2 | Growth of a rat neuroblastoma cell line in serum-free supplemented medium. | J E Bottenstein, G H Sato | Proc Natl Acad Sci U S A | 1979 | 284369 | Yes |
3223 | 2307 | 1153.5 | 43.83 | 21.9 | NF-kappaB at the crossroads of life and death. | Michael Karin, Anning Lin | Nat Immunol | 2002 | 11875461 | No |
3224 | 2307 | 1153.5 | 36.42 | 18.2 | Adenosine 3',5'-phosphate in biological materials. I. Purification and properties of cyclic 3',5'-nucleotide phosphodiesterase and use of this enzyme to characterize adenosine 3',5'-phosphate in human urine. | R W Butcher, E W Sutherland | J Biol Chem | 1962 | 13875173 | Yes |
3225 | 2306 | 1153.0 | 46.45 | 23.2 | A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. | N C Andrews, D V Faller | Nucleic Acids Res | 1991 | 2041787 | Yes |
3226 | 1153 | 1153.0 | 24.24 | 24.2 | Stem cells in the central nervous system. | R McKay | Science | 1997 | 9082987 | No |
3227 | 1153 | 1153.0 | 22.06 | 22.1 | Mechanisms and consequences of activation of protein kinase B/Akt. | J Downward | Curr Opin Cell Biol | 1998 | 9561851 | No |
3228 | 1153 | 1153.0 | 22.16 | 22.2 | Regulation of cadherin-mediated adhesion in morphogenesis. | Barry M Gumbiner | Nat Rev Mol Cell Biol | 2005 | 16025097 | No |
3229 | 3459 | 1153.0 | 103.62 | 34.5 | SeaView version 4: A multiplatform graphical user interface for sequence alignment and phylogenetic tree building. | Manolo Gouy, Stéphane Guindon, Olivier Gascuel | Mol Biol Evol | 2010 | 19854763 | Yes |
3230 | 2305 | 1152.5 | 66.63 | 33.3 | Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. | P Brugada, J Brugada | J Am Coll Cardiol | 1992 | 1309182 | Yes |
3231 | 2305 | 1152.5 | 70.96 | 35.5 | Role of oxidized low density lipoprotein in atherogenesis. | J L Witztum, D Steinberg | J Clin Invest | 1991 | 1752940 | No |
3232 | 1152 | 1152.0 | 25.13 | 25.1 | G-quartets 40 years later: from 5'-GMP to molecular biology and supramolecular chemistry. | Jeffery T Davis | Angew Chem Int Ed Engl | 2004 | 14755695 | No |
3233 | 3456 | 1152.0 | 91.24 | 30.4 | Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? | Dunyaporn Trachootham, Jerome Alexandre, Peng Huang | Nat Rev Drug Discov | 2009 | 19478820 | No |
3234 | 8062 | 1151.7 | 281.17 | 40.2 | Metagenomic biomarker discovery and explanation. | Nicola Segata, Jacques Izard, Levi Waldron, Dirk Gevers, Larisa Miropolsky, Wendy S Garrett, Curtis Huttenhower | Genome Biol | 2011 | 21702898 | Yes |
3235 | 2303 | 1151.5 | 43.56 | 21.8 | Rho GTPases: biochemistry and biology. | Aron B Jaffe, Alan Hall | Annu Rev Cell Dev Biol | 2005 | 16212495 | No |
3236 | 1151 | 1151.0 | 27.27 | 27.3 | Selective coronary arteriography. I. A percutaneous transfemoral technic. | M P Judkins | Radiology | 1967 | 6048074 | Yes |
3237 | 2302 | 1151.0 | 76.86 | 38.4 | Pharmaceuticals and personal care products in the environment: agents of subtle change? | C G Daughton, T A Ternes | Environ Health Perspect | 1999 | 10592150 | No |
3238 | 1151 | 1151.0 | 41.32 | 41.3 | Postural orientation and equilibrium: what do we need to know about neural control of balance to prevent falls? | Fay B Horak | Age Ageing | 2006 | 16926210 | No |
3239 | 1151 | 1151.0 | 35.25 | 35.2 | A practical solution to the pervasive problems of p values. | Eric-Jan Wagenmakers | Psychon Bull Rev | 2007 | 18087943 | Yes |
3240 | 1150 | 1150.0 | 35.97 | 36.0 | Relations between the statistics of natural images and the response properties of cortical cells. | D J Field | J Opt Soc Am A | 1987 | 3430225 | Yes |
3241 | 2300 | 1150.0 | 56.52 | 28.3 | Plasminogen: purification from human plasma by affinity chromatography. | D G Deutsch, E T Mertz | Science | 1970 | 5475635 | Yes |
3242 | 1150 | 1150.0 | 24.27 | 24.3 | Epstein-Barr virus infection. | J I Cohen | N Engl J Med | 2000 | 10944566 | No |
3243 | 1150 | 1150.0 | 0.0 | 0.0 | A sensitive method for the assay of 5-hydroxytryptamine. | J R Vane | Br J Pharmacol Chemother | 1957 | 13460242 | Yes |
3244 | 2300 | 1150.0 | 47.86 | 23.9 | Protein aggregation and neurodegenerative disease. | Christopher A Ross, Michelle A Poirier | Nat Med | 2004 | 15272267 | No |
3245 | 1149 | 1149.0 | 33.07 | 33.1 | Nature of Col E 1 plasmid replication in Escherichia coli in the presence of the chloramphenicol. | D B Clewell | J Bacteriol | 1972 | 4336693 | Yes |
3246 | 1149 | 1149.0 | 31.39 | 31.4 | Leishmaniasis. | B L Herwaldt | Lancet | 1999 | 10513726 | No |
3247 | 1149 | 1149.0 | 29.43 | 29.4 | The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. | R A Jain | Biomaterials | 2000 | 11055295 | No |
3248 | 1149 | 1149.0 | 24.79 | 24.8 | Serine protease mechanism and specificity. | Lizbeth Hedstrom | Chem Rev | 2002 | 12475199 | No |
3249 | 2297 | 1148.5 | 109.39 | 54.7 | Research diagnostic criteria for temporomandibular disorders: review, criteria, examinations and specifications, critique. | S F Dworkin, L LeResche | J Craniomandib Disord | 1992 | 1298767 | No |
3250 | 2297 | 1148.5 | 89.71 | 44.9 | A simple method to assess exercise behavior in the community. | G Godin, R J Shephard | Can J Appl Sport Sci | 1985 | 4053261 | Yes |
3251 | 1148 | 1148.0 | 43.22 | 43.2 | Molecular aspects of ligand binding to serum albumin. | U Kragh-Hansen | Pharmacol Rev | 1981 | 7027277 | No |
3252 | 2296 | 1148.0 | 67.18 | 33.6 | Nitric oxide synthases in mammals. | R G Knowles, S Moncada | Biochem J | 1994 | 7510950 | No |
3253 | 2296 | 1148.0 | 51.69 | 25.8 | Shape-controlled synthesis of gold and silver nanoparticles. | Yugang Sun, Younan Xia | Science | 2002 | 12481134 | Yes |
3254 | 1148 | 1148.0 | 27.8 | 27.8 | Mode of action of membrane active antimicrobial peptides. | Yechiel Shai | Biopolymers | 2002 | 12491537 | No |
3255 | 2296 | 1148.0 | 50.47 | 25.2 | Esophageal cancer. | Peter C Enzinger, Robert J Mayer | N Engl J Med | 2003 | 14657432 | No |
3256 | 2296 | 1148.0 | 54.23 | 27.1 | Endometriosis. | Linda C Giudice, Lee C Kao | Lancet | 2004 | 15541453 | No |
3257 | 1148 | 1148.0 | 28.09 | 28.1 | Nanoparticles, Proteins, and Nucleic Acids: Biotechnology Meets Materials Science. | Christof M Niemeyer | Angew Chem Int Ed Engl | 2001 | 29712109 | No |
3258 | 2295 | 1147.5 | 50.57 | 25.3 | Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set. | N Sreerama, R W Woody | Anal Biochem | 2000 | 11112271 | Yes |
3259 | 1147 | 1147.0 | 48.33 | 48.3 | A spreading-activation theory of retrieval in sentence production. | G S Dell | Psychol Rev | 1986 | 3749399 | Yes |
3260 | 1147 | 1147.0 | 31.93 | 31.9 | DNA topoisomerases. | M Gellert | Annu Rev Biochem | 1981 | 6267993 | No |
3261 | 2294 | 1147.0 | 67.45 | 33.7 | The capacity of visual working memory for features and conjunctions. | S J Luck, E K Vogel | Nature | 1997 | 9384378 | Yes |
3262 | 1147 | 1147.0 | 0.0 | 0.0 | The perceptron: a probabilistic model for information storage and organization in the brain. | F Rosenblatt | Psychol Rev | 1958 | 13602029 | Yes |
3263 | 3441 | 1147.0 | 95.75 | 31.9 | Regulation of cancer cell metabolism. | Rob A Cairns, Isaac S Harris, Tak W Mak | Nat Rev Cancer | 2011 | 21258394 | No |
3264 | 1147 | 1147.0 | 48.96 | 49.0 | The prevalence of DSM-IV attention-deficit/hyperactivity disorder: a meta-analytic review. | Erik G Willcutt | Neurotherapeutics | 2012 | 22976615 | No |
3265 | 3439 | 1146.3 | 91.51 | 30.5 | Matrix metalloproteinases: regulators of the tumor microenvironment. | Kai Kessenbrock, Vicki Plaks, Zena Werb | Cell | 2010 | 20371345 | No |
3266 | 1146 | 1146.0 | 31.11 | 31.1 | Diseases of the mitochondrial DNA. | D C Wallace | Annu Rev Biochem | 1992 | 1497308 | No |
3267 | 4584 | 1146.0 | 110.98 | 27.7 | Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. | H Nielsen, J Engelbrecht, S Brunak, G von Heijne | Protein Eng | 1997 | 9051728 | Yes |
3268 | 1146 | 1146.0 | 32.81 | 32.8 | Rethinking schizophrenia. | Thomas R Insel | Nature | 2010 | 21068826 | No |
3269 | 2292 | 1146.0 | 93.21 | 46.6 | Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation. | Ulrich M Zanger, Matthias Schwab | Pharmacol Ther | 2013 | 23333322 | No |
3270 | 3437 | 1145.7 | 216.51 | 72.2 | Production, use, and fate of all plastics ever made. | Roland Geyer, Jenna R Jambeck, Kara Lavender Law | Sci Adv | 2017 | 28776036 | Yes |
3271 | 3436 | 1145.3 | 87.88 | 29.3 | The widespread regulation of microRNA biogenesis, function and decay. | Jacek Krol, Inga Loedige, Witold Filipowicz | Nat Rev Genet | 2010 | 20661255 | No |
3272 | 1145 | 1145.0 | 33.34 | 33.3 | Animal mitochondrial DNA: structure and evolution. | D R Wolstenholme | Int Rev Cytol | 1992 | 1452431 | No |
3273 | 1145 | 1145.0 | 42.01 | 42.0 | Omega-3 fatty acids in health and disease and in growth and development. | A P Simopoulos | Am J Clin Nutr | 1991 | 1908631 | No |
3274 | 1145 | 1145.0 | 0.0 | 0.0 | The powerful placebo. | H K Beecher | J Am Med Assoc | 1955 | 13271123 | Yes |
3275 | 1145 | 1145.0 | 22.35 | 22.4 | Inferences, questions and possibilities in Toll-like receptor signalling. | Bruce Beutler | Nature | 2004 | 15241424 | No |
3276 | 2289 | 1144.5 | 61.14 | 30.6 | BODIPY dyes and their derivatives: syntheses and spectroscopic properties. | Aurore Loudet, Kevin Burgess | Chem Rev | 2007 | 17924696 | Yes |
3277 | 2289 | 1144.5 | 68.03 | 34.0 | Type 2 diabetes as an inflammatory disease. | Marc Y Donath, Steven E Shoelson | Nat Rev Immunol | 2011 | 21233852 | No |
3278 | 1144 | 1144.0 | 45.44 | 45.4 | Radioimmunological determination of human C-peptide in serum. | L G Heding | Diabetologia | 1975 | 1239396 | Yes |
3279 | 1144 | 1144.0 | 32.98 | 33.0 | An improved fluorometric assay for DNA. | R T Hinegardner | Anal Biochem | 1971 | 5544593 | Yes |
3280 | 2288 | 1144.0 | 68.31 | 34.2 | Multiple significance tests: the Bonferroni method. | J M Bland, D G Altman | BMJ | 1995 | 7833759 | Yes |
3281 | 1144 | 1144.0 | 7.06 | 7.1 | A New Serum Type System In Man--The Lp System. | K Berg | Acta Pathol Microbiol Scand | 1963 | 14064818 | Yes |
3282 | 1144 | 1144.0 | 30.06 | 30.1 | A theory of magnitude: common cortical metrics of time, space and quantity. | Vincent Walsh | Trends Cogn Sci | 2003 | 14585444 | Yes |
3283 | 1144 | 1144.0 | 24.02 | 24.0 | Version 1.2 of the Crystallography and NMR system. | Axel T Brunger | Nat Protoc | 2007 | 18007608 | Yes |
3284 | 3432 | 1144.0 | 604.58 | 201.5 | MEGA11: Molecular Evolutionary Genetics Analysis Version 11. | Koichiro Tamura, Glen Stecher, Sudhir Kumar | Mol Biol Evol | 2021 | 33892491 | Yes |
3285 | 2287 | 1143.5 | 47.26 | 23.6 | Plant pathogens and integrated defence responses to infection. | J L Dangl, J D Jones | Nature | 2001 | 11459065 | No |
3286 | 3429 | 1143.0 | 107.88 | 36.0 | Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate. | G M Wahl, M Stern, G R Stark | Proc Natl Acad Sci U S A | 1979 | 291033 | Yes |
3287 | 2286 | 1143.0 | 66.48 | 33.2 | A rating scale for extrapyramidal side effects. | G M Simpson, J W Angus | Acta Psychiatr Scand Suppl | 1970 | 4917967 | Yes |
3288 | 1143 | 1143.0 | 0.0 | 0.0 | Fertilizing capacity of spermatozoa deposited into the fallopian tubes. | M C Chang | Nature | 1951 | 14882325 | Yes |
3289 | 2286 | 1143.0 | 48.1 | 24.1 | Regulation of translation initiation in eukaryotes: mechanisms and biological targets. | Nahum Sonenberg, Alan G Hinnebusch | Cell | 2009 | 19239892 | No |
3290 | 1143 | 1143.0 | 57.38 | 57.4 | The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease. | Costantino Iadecola | Neuron | 2017 | 28957666 | No |
3291 | 2285 | 1142.5 | 53.82 | 26.9 | ZINC--a free database of commercially available compounds for virtual screening. | John J Irwin, Brian K Shoichet | J Chem Inf Model | 2005 | 15667143 | Yes |
3292 | 6853 | 1142.2 | 228.12 | 38.0 | The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. | Erik von Elm, Douglas G Altman, Matthias Egger, Stuart J Pocock, Peter C Gøtzsche, Jan P Vandenbroucke | J Clin Epidemiol | 2008 | 18313558 | Yes |
3293 | 1142 | 1142.0 | 33.36 | 33.4 | Reducing children's television viewing to prevent obesity: a randomized controlled trial. | T N Robinson | JAMA | 1999 | 10546696 | Yes |
3294 | 6849 | 1141.5 | 198.08 | 33.0 | The unity and diversity of executive functions and their contributions to complex "Frontal Lobe" tasks: a latent variable analysis. | A Miyake, N P Friedman, M J Emerson, A H Witzki, A Howerter, T D Wager | Cogn Psychol | 2000 | 10945922 | Yes |
3295 | 1141 | 1141.0 | 16.58 | 16.6 | Biochemistry of dystrophic muscle. Mitochondrial succinate-tetrazolium reductase and adenosine triphosphatase. | R J Pennington | Biochem J | 1961 | 13734134 | Yes |
3296 | 1141 | 1141.0 | 21.35 | 21.4 | Diffusion-in-gel methods for immunological analysis. II. | O Ouchterlony | Prog Allergy | 1962 | 14482809 | Yes |
3297 | 1141 | 1141.0 | 25.39 | 25.4 | Next-generation DNA sequencing methods. | Elaine R Mardis | Annu Rev Genomics Hum Genet | 2008 | 18576944 | No |
3298 | 2281 | 1140.5 | 44.46 | 22.2 | Homeobox genes and axial patterning. | W McGinnis, R Krumlauf | Cell | 1992 | 1346368 | No |
3299 | 1140 | 1140.0 | 28.66 | 28.7 | Two-stage model of memory trace formation: a role for "noisy" brain states. | G Buzsáki | Neuroscience | 1989 | 2687720 | No |
3300 | 1140 | 1140.0 | 55.94 | 55.9 | The tension-stress effect on the genesis and growth of tissues. Part I. The influence of stability of fixation and soft-tissue preservation. | G A Ilizarov | Clin Orthop Relat Res | 1989 | 2910611 | Yes |
3301 | 1140 | 1140.0 | 40.42 | 40.4 | Neurotoxins that act on voltage-sensitive sodium channels in excitable membranes. | W A Catterall | Annu Rev Pharmacol Toxicol | 1980 | 6247957 | No |
3302 | 1140 | 1140.0 | 21.25 | 21.2 | Regulation of phosphoinositide-specific phospholipase C. | S G Rhee | Annu Rev Biochem | 2001 | 11395409 | No |
3303 | 2280 | 1140.0 | 50.75 | 25.4 | microRNA functions. | Natascha Bushati, Stephen M Cohen | Annu Rev Cell Dev Biol | 2007 | 17506695 | No |
3304 | 2279 | 1139.5 | 60.26 | 30.1 | Analysis of gene control signals by DNA fusion and cloning in Escherichia coli. | M J Casadaban, S N Cohen | J Mol Biol | 1980 | 6997493 | Yes |
3305 | 6836 | 1139.3 | 153.34 | 25.6 | Principal components analysis corrects for stratification in genome-wide association studies. | Alkes L Price, Nick J Patterson, Robert M Plenge, Michael E Weinblatt, Nancy A Shadick, David Reich | Nat Genet | 2006 | 16862161 | Yes |
3306 | 1139 | 1139.0 | 25.56 | 25.6 | Estimating absolute rates of molecular evolution and divergence times: a penalized likelihood approach. | Michael J Sanderson | Mol Biol Evol | 2002 | 11752195 | Yes |
3307 | 1139 | 1139.0 | 21.48 | 21.5 | The power and the promise of DNA methylation markers. | Peter W Laird | Nat Rev Cancer | 2003 | 12671664 | No |
3308 | 1139 | 1139.0 | 35.39 | 35.4 | Polybrominated diphenyl ethers in the environment and in people: a meta-analysis of concentrations. | Ronald A Hites | Environ Sci Technol | 2004 | 14998004 | Yes |
3309 | 1138 | 1138.0 | 22.03 | 22.0 | Structure of chromatin. | R D Kornberg | Annu Rev Biochem | 1977 | 332067 | No |
3310 | 2276 | 1138.0 | 46.56 | 23.3 | Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. | G A Gonzalez, M R Montminy | Cell | 1989 | 2573431 | Yes |
3311 | 1138 | 1138.0 | 59.25 | 59.2 | A "rationalized" arcsine transform. | G A Studebaker | J Speech Hear Res | 1985 | 4046587 | Yes |
3312 | 1138 | 1138.0 | 57.49 | 57.5 | Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review. | Dariush Mozaffarian | Circulation | 2016 | 26746178 | No |
3313 | 3413 | 1137.7 | 97.32 | 32.4 | A sensitive and reliable locomotor rating scale for open field testing in rats. | D M Basso, M S Beattie, J C Bresnahan | J Neurotrauma | 1995 | 7783230 | Yes |
3314 | 2275 | 1137.5 | 0.0 | 0.0 | Active transport of sodium as the source of electric current in the short-circuited isolated frog skin. | H H Ussing, K Zerahn | Acta Physiol Scand | 1951 | 14868510 | Yes |
3315 | 1137 | 1137.0 | 33.73 | 33.7 | Unstable angina. A classification. | E Braunwald | Circulation | 1989 | 2752565 | Yes |
3316 | 3411 | 1137.0 | 96.43 | 32.1 | Cytochemical identification of monocytes and granulocytes. | L T Yam, C Y Li, W H Crosby | Am J Clin Pathol | 1971 | 5549896 | Yes |
3317 | 1137 | 1137.0 | 31.38 | 31.4 | Riddle of biofilm resistance. | K Lewis | Antimicrob Agents Chemother | 2001 | 11257008 | No |
3318 | 1137 | 1137.0 | 26.67 | 26.7 | Transcriptional paradigms in mammalian mitochondrial biogenesis and function. | Richard C Scarpulla | Physiol Rev | 2008 | 18391175 | No |
3319 | 1137 | 1137.0 | 27.55 | 27.6 | Correlates of protection induced by vaccination. | Stanley A Plotkin | Clin Vaccine Immunol | 2010 | 20463105 | No |
3320 | 1136 | 1136.0 | 20.16 | 20.2 | Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation. | Eric C Lai | Nat Genet | 2002 | 11896390 | Yes |
3321 | 1136 | 1136.0 | 21.9 | 21.9 | VEGF and the quest for tumour angiogenesis factors. | Napoleone Ferrara | Nat Rev Cancer | 2002 | 12360282 | No |
3322 | 1136 | 1136.0 | 49.73 | 49.7 | How neuroinflammation contributes to neurodegeneration. | Richard M Ransohoff | Science | 2016 | 27540165 | No |
3323 | 3407 | 1135.7 | 106.52 | 35.5 | Development and applications of CRISPR-Cas9 for genome engineering. | Patrick D Hsu, Eric S Lander, Feng Zhang | Cell | 2014 | 24906146 | No |
3324 | 2271 | 1135.5 | 66.76 | 33.4 | Health effects of fine particulate air pollution: lines that connect. | C Arden Pope, Douglas W Dockery | J Air Waste Manag Assoc | 2006 | 16805397 | No |
3325 | 2270 | 1135.0 | 91.14 | 45.6 | Rapid genetic identification and mapping of enzymatically amplified ribosomal DNA from several Cryptococcus species. | R Vilgalys, M Hester | J Bacteriol | 1990 | 2376561 | Yes |
3326 | 1135 | 1135.0 | 46.36 | 46.4 | The PEDro scale is a valid measure of the methodological quality of clinical trials: a demographic study. | Natalie A de Morton | Aust J Physiother | 2009 | 19463084 | Yes |
3327 | 3405 | 1135.0 | 144.1 | 48.0 | Principles of nanoparticle design for overcoming biological barriers to drug delivery. | Elvin Blanco, Haifa Shen, Mauro Ferrari | Nat Biotechnol | 2015 | 26348965 | Yes |
3328 | 2269 | 1134.5 | 49.11 | 24.6 | Deep tissue two-photon microscopy. | Fritjof Helmchen, Winfried Denk | Nat Methods | 2005 | 16299478 | No |
3329 | 1134 | 1134.0 | 42.3 | 42.3 | Second generation logarithmic estimates of single-pool variable volume Kt/V: an analysis of error. | J T Daugirdas | J Am Soc Nephrol | 1993 | 8305648 | Yes |
3330 | 1134 | 1134.0 | 30.77 | 30.8 | A toxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors. | Ron Hardman | Environ Health Perspect | 2006 | 16451849 | No |
3331 | 11334 | 1133.4 | 446.57 | 44.7 | MrBayes 3.2: efficient Bayesian phylogenetic inference and model choice across a large model space. | Fredrik Ronquist, Maxim Teslenko, Paul van der Mark, Daniel L Ayres, Aaron Darling, Sebastian Höhna, Bret Larget, Liang Liu, Marc A Suchard, John P Huelsenbeck | Syst Biol | 2012 | 22357727 | Yes |
3332 | 1133 | 1133.0 | 49.72 | 49.7 | Sixth gaddum memorial lecture, National Institute for Medical Research, Mill Hill, January 1977. Presynaptic receptors and their role in the regulation of transmitter release. | S Z Langer | Br J Pharmacol | 1977 | 20190 | No |
3333 | 1133 | 1133.0 | 22.12 | 22.1 | Regulation of transcription by MAP kinase cascades. | R Treisman | Curr Opin Cell Biol | 1996 | 8791420 | No |
3334 | 1133 | 1133.0 | 26.51 | 26.5 | Aptamers: an emerging class of molecules that rival antibodies in diagnostics. | S D Jayasena | Clin Chem | 1999 | 10471678 | No |
3335 | 1133 | 1133.0 | 30.64 | 30.6 | AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function. | D Grahame Hardie | Genes Dev | 2011 | 21937710 | No |
3336 | 1133 | 1133.0 | 46.13 | 46.1 | The biology and function of exosomes in cancer. | Raghu Kalluri | J Clin Invest | 2016 | 27035812 | No |
3337 | 1132 | 1132.0 | 26.12 | 26.1 | Allelic discrimination using fluorogenic probes and the 5' nuclease assay. | K J Livak | Genet Anal | 1999 | 10084106 | Yes |
3338 | 1132 | 1132.0 | 30.72 | 30.7 | Venous thrombosis: a multicausal disease. | F R Rosendaal | Lancet | 1999 | 10209995 | No |
3339 | 1132 | 1132.0 | 20.4 | 20.4 | The development of neural stem cells. | S Temple | Nature | 2001 | 11689956 | No |
3340 | 2264 | 1132.0 | 42.42 | 21.2 | The druggable genome. | Andrew L Hopkins, Colin R Groom | Nat Rev Drug Discov | 2002 | 12209152 | No |
3341 | 1132 | 1132.0 | 0.0 | 0.0 | A microchemical reaction resulting in the staining of polysaccharide structures in fixed tissue preparations. | R D Hotchkiss | Arch Biochem | 1948 | 18921848 | Yes |
3342 | 1132 | 1132.0 | 50.25 | 50.2 | Canadian Diabetes Association 2013 clinical practice guidelines for the prevention and management of diabetes in Canada. Introduction. | Alice Y Y Cheng | Can J Diabetes | 2013 | 24070926 | No |
3343 | 1132 | 1132.0 | 64.81 | 64.8 | Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features and Rome IV. | Douglas A Drossman | Gastroenterology | 2016 | 27144617 | Yes |
3344 | 2263 | 1131.5 | 77.25 | 38.6 | A simple index of Crohn's-disease activity. | R F Harvey, J M Bradshaw | Lancet | 1980 | 6102236 | Yes |
3345 | 2263 | 1131.5 | 44.51 | 22.3 | Tumour-cell invasion and migration: diversity and escape mechanisms. | Peter Friedl, Katarina Wolf | Nat Rev Cancer | 2003 | 12724734 | No |
3346 | 3394 | 1131.3 | 72.31 | 24.1 | A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. | M Serrano, G J Hannon, D Beach | Nature | 1993 | 8259215 | Yes |
3347 | 2262 | 1131.0 | 58.37 | 29.2 | Protein oxidation in aging, disease, and oxidative stress. | B S Berlett, E R Stadtman | J Biol Chem | 1997 | 9252331 | No |
3348 | 1131 | 1131.0 | 23.87 | 23.9 | Molecular imaging of cancer with positron emission tomography. | Sanjiv Sam Gambhir | Nat Rev Cancer | 2002 | 12209157 | No |
3349 | 1131 | 1131.0 | 23.1 | 23.1 | Understanding the odd science of aging. | Thomas B L Kirkwood | Cell | 2005 | 15734677 | No |
3350 | 1131 | 1131.0 | 31.87 | 31.9 | Neurophysiological and computational principles of cortical rhythms in cognition. | Xiao-Jing Wang | Physiol Rev | 2010 | 20664082 | No |
3351 | 2262 | 1131.0 | 99.18 | 49.6 | The lifelong effects of early childhood adversity and toxic stress. | Jack P Shonkoff, Andrew S Garner | Pediatrics | 2012 | 22201156 | Yes |
3352 | 2261 | 1130.5 | 20.95 | 10.5 | A Generalization Of The Retention Index System Including Linear Temperature Programmed Gas-Liquid Partition Chromatography. | H Vandendool, P D Kratz | J Chromatogr | 1963 | 14062605 | Yes |
3353 | 3391 | 1130.3 | 91.35 | 30.4 | Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. | Robert G Hart, Lesly A Pearce, Maria I Aguilar | Ann Intern Med | 2007 | 17577005 | Yes |
3354 | 1130 | 1130.0 | 28.27 | 28.3 | Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture. | I J Fidler | Cancer Res | 1990 | 1698118 | Yes |
3355 | 2259 | 1129.5 | 51.35 | 25.7 | The Polycomb complex PRC2 and its mark in life. | Raphaël Margueron, Danny Reinberg | Nature | 2011 | 21248841 | No |
3356 | 1129 | 1129.0 | 27.94 | 27.9 | Stereochemical criteria for polypeptides and proteins. V. Conformation of a system of three linked peptide units. | C M Venkatachalam | Biopolymers | 1968 | 5685102 | Yes |
3357 | 1129 | 1129.0 | 38.25 | 38.2 | Selective attention and the organization of visual information. | J Duncan | J Exp Psychol Gen | 1984 | 6240521 | Yes |
3358 | 1129 | 1129.0 | 36.19 | 36.2 | Predictors of postpartum depression: an update. | C T Beck | Nurs Res | 2001 | 11570712 | Yes |
3359 | 1129 | 1129.0 | 30.22 | 30.2 | Disseminating innovations in health care. | Donald M Berwick | JAMA | 2003 | 12697800 | Yes |
3360 | 1129 | 1129.0 | 30.73 | 30.7 | Stronger Brønsted acids. | Takahiko Akiyama | Chem Rev | 2007 | 17983247 | Yes |
3361 | 2257 | 1128.5 | 53.98 | 27.0 | Toxoplasmosis. | J G Montoya, O Liesenfeld | Lancet | 2004 | 15194258 | No |
3362 | 1128 | 1128.0 | 23.49 | 23.5 | Evolution of ageing. | T B Kirkwood | Nature | 1977 | 593350 | Yes |
3363 | 3384 | 1128.0 | 90.62 | 30.2 | Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. | R Schreck, P Rieber, P A Baeuerle | EMBO J | 1991 | 2065663 | Yes |
3364 | 1128 | 1128.0 | 38.52 | 38.5 | Radioimmunoassay: a method for human chorionic gonadotropin and human luteinizing hormone. | A R Midgley | Endocrinology | 1966 | 5950482 | Yes |
3365 | 1128 | 1128.0 | 14.83 | 14.8 | The nature and significance of platelet products in human plasma. | P Wolf | Br J Haematol | 1967 | 6025241 | Yes |
3366 | 1128 | 1128.0 | 30.23 | 30.2 | The chromosomal basis of human neoplasia. | J J Yunis | Science | 1983 | 6336310 | Yes |
3367 | 1128 | 1128.0 | 24.69 | 24.7 | r8s: inferring absolute rates of molecular evolution and divergence times in the absence of a molecular clock. | Michael J Sanderson | Bioinformatics | 2003 | 12538260 | Yes |
3368 | 2256 | 1128.0 | 68.86 | 34.4 | Self-management education: history, definition, outcomes, and mechanisms. | Kate R Lorig, Halsted Holman | Ann Behav Med | 2003 | 12867348 | No |
3369 | 2256 | 1128.0 | 73.1 | 36.5 | Long non-coding RNAs: new players in cell differentiation and development. | Alessandro Fatica, Irene Bozzoni | Nat Rev Genet | 2014 | 24296535 | No |
3370 | 2255 | 1127.5 | 32.82 | 16.4 | Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases. | L M Siegel, K J Monty | Biochim Biophys Acta | 1966 | 5329026 | Yes |
3371 | 2255 | 1127.5 | 68.54 | 34.3 | Mitochondrial fission, fusion, and stress. | Richard J Youle, Alexander M van der Bliek | Science | 2012 | 22936770 | No |
3372 | 1127 | 1127.0 | 54.64 | 54.6 | Self-discrepancy: a theory relating self and affect. | E T Higgins | Psychol Rev | 1987 | 3615707 | Yes |
3373 | 1127 | 1127.0 | 31.91 | 31.9 | Cholesterol and the cell membrane. | P L Yeagle | Biochim Biophys Acta | 1985 | 3904832 | No |
3374 | 1127 | 1127.0 | 28.61 | 28.6 | Intestinal epithelial cell surface membrane glycoprotein synthesis. I. An indicator of cellular differentiation. | M M Weiser | J Biol Chem | 1973 | 4698230 | Yes |
3375 | 1127 | 1127.0 | 42.55 | 42.5 | On the regulation and control of fibrinolysis. Edward Kowalski Memorial Lecture. | D Collen | Thromb Haemost | 1980 | 6450468 | No |
3376 | 1127 | 1127.0 | 23.11 | 23.1 | Differentiation and proliferation of hematopoietic stem cells. | M Ogawa | Blood | 1993 | 8499622 | No |
3377 | 2254 | 1127.0 | 60.81 | 30.4 | Mechanisms of biofilm resistance to antimicrobial agents. | T F Mah, G A O'Toole | Trends Microbiol | 2001 | 11166241 | No |
3378 | 1127 | 1127.0 | 0.0 | 0.0 | Micromethods for the study of proteins and antibodies. I. Procedure and general applications of hemagglutination and hemagglutination-inhibition reactions with tannic acid and protein-treated red blood cells. | A B Stavitsky | J Immunol | 1954 | 13163409 | Yes |
3379 | 2254 | 1127.0 | 54.11 | 27.1 | ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis. | Benoît D'Autréaux, Michel B Toledano | Nat Rev Mol Cell Biol | 2007 | 17848967 | No |
3380 | 1127 | 1127.0 | 71.1 | 71.1 | Information bias in health research: definition, pitfalls, and adjustment methods. | Alaa Althubaiti | J Multidiscip Healthc | 2016 | 27217764 | No |
3381 | 1126 | 1126.0 | 23.64 | 23.6 | Mutator phenotype may be required for multistage carcinogenesis. | L A Loeb | Cancer Res | 1991 | 2039987 | No |
3382 | 1126 | 1126.0 | 24.94 | 24.9 | Possible role of flanking nucleotides in recognition of the AUG initiator codon by eukaryotic ribosomes. | M Kozak | Nucleic Acids Res | 1981 | 7301588 | Yes |
3383 | 1126 | 1126.0 | 23.93 | 23.9 | Fluorescence spectroscopy of single biomolecules. | S Weiss | Science | 1999 | 10073925 | No |
3384 | 1126 | 1126.0 | 20.59 | 20.6 | DNA methylation in cancer: too much, but also too little. | Melanie Ehrlich | Oncogene | 2002 | 12154403 | No |
3385 | 1126 | 1126.0 | 0.0 | 0.0 | Knee joint changes after meniscectomy. | T J Fairbank | J Bone Joint Surg Br | 1948 | 18894618 | Yes |
3386 | 1126 | 1126.0 | 0.0 | 0.0 | pA, a new scale for the measurement of drug antagonism. | H O Schild | Br J Pharmacol Chemother | 1947 | 20258355 | Yes |
3387 | 1126 | 1126.0 | 43.5 | 43.5 | Review of the key results from the Swedish Obese Subjects (SOS) trial - a prospective controlled intervention study of bariatric surgery. | L Sjöström | J Intern Med | 2013 | 23163728 | No |
3388 | 2251 | 1125.5 | 75.47 | 37.7 | Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. | A E Czeizel, I Dudás | N Engl J Med | 1992 | 1307234 | Yes |
3389 | 2251 | 1125.5 | 55.0 | 27.5 | The protective effects of estrogen on the cardiovascular system. | M E Mendelsohn, R H Karas | N Engl J Med | 1999 | 10362825 | No |
3390 | 1125 | 1125.0 | 26.53 | 26.5 | Mechanisms of lipid peroxide formation in animal tissues. | E D Wills | Biochem J | 1966 | 5964963 | Yes |
3391 | 1125 | 1125.0 | 33.13 | 33.1 | Cell surface interactions with extracellular materials. | K M Yamada | Annu Rev Biochem | 1983 | 6351729 | No |
3392 | 2250 | 1125.0 | 49.04 | 24.5 | Regeneration beyond the glial scar. | Jerry Silver, Jared H Miller | Nat Rev Neurosci | 2004 | 14735117 | No |
3393 | 1125 | 1125.0 | 27.73 | 27.7 | Formation and function of the myofibroblast during tissue repair. | Boris Hinz | J Invest Dermatol | 2007 | 17299435 | No |
3394 | 2249 | 1124.5 | 59.16 | 29.6 | Oxidative stress, caloric restriction, and aging. | R S Sohal, R Weindruch | Science | 1996 | 8658196 | No |
3395 | 2249 | 1124.5 | 51.04 | 25.5 | Next-generation DNA sequencing. | Jay Shendure, Hanlee Ji | Nat Biotechnol | 2008 | 18846087 | Yes |
3396 | 1124 | 1124.0 | 67.48 | 67.5 | Cytoprotection by prostaglandins. | A Robert | Gastroenterology | 1979 | 38173 | Yes |
3397 | 1124 | 1124.0 | 32.69 | 32.7 | Modeling tracer kinetics in dynamic Gd-DTPA MR imaging. | P S Tofts | J Magn Reson Imaging | 1997 | 9039598 | No |
3398 | 1124 | 1124.0 | 0.0 | 0.0 | The degree of masculine differentiation of obesities: a factor determining predisposition to diabetes, atherosclerosis, gout, and uric calculous disease. | J Vague | Am J Clin Nutr | 1956 | 13282851 | Yes |
3399 | 1124 | 1124.0 | 17.25 | 17.2 | Inherited Antithrombin Deficiency Causing Thrombophilia. | O Egeberg | Thromb Diath Haemorrh | 1965 | 14347873 | Yes |
3400 | 2248 | 1124.0 | 50.03 | 25.0 | Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. | William G Kaelin, Peter J Ratcliffe | Mol Cell | 2008 | 18498744 | No |
3401 | 2247 | 1123.5 | 88.54 | 44.3 | Statistical methods for assessing measurement error (reliability) in variables relevant to sports medicine. | G Atkinson, A M Nevill | Sports Med | 1998 | 9820922 | No |
3402 | 1123 | 1123.0 | 23.44 | 23.4 | ALSCRIPT: a tool to format multiple sequence alignments. | G J Barton | Protein Eng | 1993 | 8433969 | Yes |
3403 | 2245 | 1122.5 | 51.15 | 25.6 | Modes of resistance to anti-angiogenic therapy. | Gabriele Bergers, Douglas Hanahan | Nat Rev Cancer | 2008 | 18650835 | No |
3404 | 4489 | 1122.2 | 103.26 | 25.8 | SCOP: a structural classification of proteins database for the investigation of sequences and structures. | A G Murzin, S E Brenner, T Hubbard, C Chothia | J Mol Biol | 1995 | 7723011 | Yes |
3405 | 1122 | 1122.0 | 25.39 | 25.4 | The columnar organization of the neocortex. | V B Mountcastle | Brain | 1997 | 9153131 | No |
3406 | 4488 | 1122.0 | 110.41 | 27.6 | Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. | Michael D Greicius, Ben Krasnow, Allan L Reiss, Vinod Menon | Proc Natl Acad Sci U S A | 2003 | 12506194 | Yes |
3407 | 1121 | 1121.0 | 52.01 | 52.0 | Analysis of Fickian and non-Fickian drug release from polymers. | N A Peppas | Pharm Acta Helv | 1985 | 4011621 | Yes |
3408 | 1121 | 1121.0 | 29.63 | 29.6 | Time is brain--quantified. | Jeffrey L Saver | Stroke | 2006 | 16339467 | Yes |
3409 | 1121 | 1121.0 | 42.68 | 42.7 | Amyloid-β and tau: the trigger and bullet in Alzheimer disease pathogenesis. | George S Bloom | JAMA Neurol | 2014 | 24493463 | No |
3410 | 1120 | 1120.0 | 34.47 | 34.5 | Prostate specific antigen: a critical assessment of the most useful tumor marker for adenocarcinoma of the prostate. | J E Oesterling | J Urol | 1991 | 1707989 | No |
3411 | 1120 | 1120.0 | 22.0 | 22.0 | Cytokine receptor signalling. | J N Ihle | Nature | 1995 | 7566171 | No |
3412 | 2240 | 1120.0 | 48.89 | 24.4 | Prediction of protein secondary structure at better than 70% accuracy. | B Rost, C Sander | J Mol Biol | 1993 | 8345525 | Yes |
3413 | 3360 | 1120.0 | 119.75 | 39.9 | Neighborhoods and violent crime: a multilevel study of collective efficacy. | R J Sampson, S W Raudenbush, F Earls | Science | 1997 | 9252316 | Yes |
3414 | 1120 | 1120.0 | 0.0 | 0.0 | Immunogenetic Consequences Of Vascular Anastomoses Between Bovine Twins. | R D Owen | Science | 1945 | 17755278 | Yes |
3415 | 1120 | 1120.0 | 0.0 | 0.0 | Comparing individual means in the analysis of variance. | J W Tukey | Biometrics | 1949 | 18151955 | Yes |
3416 | 2238 | 1119.0 | 50.14 | 25.1 | Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission. | P van den Driessche, James Watmough | Math Biosci | 2002 | 12387915 | Yes |
3417 | 1119 | 1119.0 | 57.02 | 57.0 | Patient reported outcome measures could help transform healthcare. | Nick Black | BMJ | 2013 | 23358487 | Yes |
3418 | 4474 | 1118.5 | 107.81 | 27.0 | C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. | P M Ridker, C H Hennekens, J E Buring, N Rifai | N Engl J Med | 2000 | 10733371 | Yes |
3419 | 2237 | 1118.5 | 59.16 | 29.6 | Fitness effects on the cognitive function of older adults: a meta-analytic study. | Stanley Colcombe, Arthur F Kramer | Psychol Sci | 2003 | 12661673 | Yes |
3420 | 4472 | 1118.0 | 145.03 | 36.3 | The cholinergic hypothesis of geriatric memory dysfunction. | R T Bartus, R L Dean, B Beer, A S Lippa | Science | 1982 | 7046051 | No |
3421 | 1118 | 1118.0 | 23.97 | 24.0 | Complement. Second of two parts. | M J Walport | N Engl J Med | 2001 | 11297706 | No |
3422 | 1118 | 1118.0 | 26.28 | 26.3 | Complementing the genome with an "exposome": the outstanding challenge of environmental exposure measurement in molecular epidemiology. | Christopher Paul Wild | Cancer Epidemiol Biomarkers Prev | 2005 | 16103423 | No |
3423 | 6707 | 1117.8 | 253.44 | 42.2 | Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science. | Laura J Damschroder, David C Aron, Rosalind E Keith, Susan R Kirsh, Jeffery A Alexander, Julie C Lowery | Implement Sci | 2009 | 19664226 | Yes |
3424 | 2235 | 1117.5 | 64.33 | 32.2 | Strategies in the design of nanoparticles for therapeutic applications. | Robby A Petros, Joseph M DeSimone | Nat Rev Drug Discov | 2010 | 20616808 | No |
3425 | 5587 | 1117.4 | 235.75 | 47.1 | Integrating single-cell transcriptomic data across different conditions, technologies, and species. | Andrew Butler, Paul Hoffman, Peter Smibert, Efthymia Papalexi, Rahul Satija | Nat Biotechnol | 2018 | 29608179 | Yes |
3426 | 1117 | 1117.0 | 23.54 | 23.5 | Molecular cloning and expression of glycogen synthase kinase-3/factor A. | J R Woodgett | EMBO J | 1990 | 2164470 | Yes |
3427 | 1117 | 1117.0 | 51.48 | 51.5 | Resilience in the face of adversity. Protective factors and resistance to psychiatric disorder. | M Rutter | Br J Psychiatry | 1985 | 3830321 | Yes |
3428 | 2234 | 1117.0 | 49.73 | 24.9 | Obesity and insulin resistance. | B B Kahn, J S Flier | J Clin Invest | 2000 | 10953022 | No |
3429 | 2234 | 1117.0 | 63.44 | 31.7 | Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. | Patrick S Ward, Craig B Thompson | Cancer Cell | 2012 | 22439925 | No |
3430 | 1117 | 1117.0 | 44.27 | 44.3 | Myeloid-Derived Suppressor Cells. | Dmitry I Gabrilovich | Cancer Immunol Res | 2017 | 28052991 | No |
3431 | 6700 | 1116.7 | 153.5 | 25.6 | Staging of brain pathology related to sporadic Parkinson's disease. | Heiko Braak, Kelly Del Tredici, Udo Rüb, Rob A I de Vos, Ernst N H Jansen Steur, Eva Braak | Neurobiol Aging | 2003 | 12498954 | Yes |
3432 | 2233 | 1116.5 | 45.18 | 22.6 | A survey of telomerase activity in human cancer. | J W Shay, S Bacchetti | Eur J Cancer | 1997 | 9282118 | No |
3433 | 3349 | 1116.3 | 89.29 | 29.8 | A nonparametric method for automatic correction of intensity nonuniformity in MRI data. | J G Sled, A P Zijdenbos, A C Evans | IEEE Trans Med Imaging | 1998 | 9617910 | Yes |
3434 | 5581 | 1116.2 | 111.2 | 22.2 | Electrostatics of nanosystems: application to microtubules and the ribosome. | N A Baker, D Sept, S Joseph, M J Holst, J A McCammon | Proc Natl Acad Sci U S A | 2001 | 11517324 | Yes |
3435 | 1116 | 1116.0 | 35.8 | 35.8 | Social support and health: a review of physiological processes potentially underlying links to disease outcomes. | Bert N Uchino | J Behav Med | 2006 | 16758315 | No |
3436 | 2231 | 1115.5 | 73.14 | 36.6 | Microdroplet Assay Of Human Serum Cytotoxins. | P I Terasaki, J D Mcclelland | Nature | 1964 | 14248725 | Yes |
3437 | 1115 | 1115.0 | 36.97 | 37.0 | Chemoprevention of cancer. | L W Wattenberg | Cancer Res | 1985 | 3880665 | No |
3438 | 1115 | 1115.0 | 26.55 | 26.6 | Molecular drive: a cohesive mode of species evolution. | G Dover | Nature | 1982 | 7110332 | Yes |
3439 | 1115 | 1115.0 | 25.15 | 25.1 | The impact of next-generation sequencing technology on genetics. | Elaine R Mardis | Trends Genet | 2008 | 18262675 | No |
3440 | 2229 | 1114.5 | 48.97 | 24.5 | Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms. | R J Britten, D E Kohne | Science | 1968 | 4874239 | Yes |
3441 | 2229 | 1114.5 | 60.72 | 30.4 | Mechanisms of mitophagy. | Richard J Youle, Derek P Narendra | Nat Rev Mol Cell Biol | 2011 | 21179058 | No |
3442 | 1114 | 1114.0 | 28.53 | 28.5 | Linkage strategies for genetically complex traits. I. Multilocus models. | N Risch | Am J Hum Genet | 1990 | 2301392 | Yes |
3443 | 1114 | 1114.0 | 34.63 | 34.6 | Protein damage and degradation by oxygen radicals. I. general aspects. | K J Davies | J Biol Chem | 1987 | 3036875 | Yes |
3444 | 1114 | 1114.0 | 31.54 | 31.5 | Studies on histones. 7. Preparative methods for histone fractions from calf thymus. | E W Johns | Biochem J | 1964 | 5840387 | Yes |
3445 | 2228 | 1114.0 | 69.79 | 34.9 | Excitatory amino acid transmitters. | J C Watkins, R H Evans | Annu Rev Pharmacol Toxicol | 1981 | 6112965 | No |
3446 | 1114 | 1114.0 | 20.64 | 20.6 | The ubiquitin-proteasome pathway: on protein death and cell life. | A Ciechanover | EMBO J | 1998 | 9857172 | No |
3447 | 1114 | 1114.0 | 25.62 | 25.6 | Large Amplitude Elastic Motions in Proteins from a Single-Parameter, Atomic Analysis. | M M Tirion | Phys Rev Lett | 1996 | 10063201 | Yes |
3448 | 1114 | 1114.0 | 37.49 | 37.5 | A review of psychological risk factors in back and neck pain. | S J Linton | Spine (Phila Pa 1976) | 2000 | 10788861 | No |
3449 | 1114 | 1114.0 | 31.96 | 32.0 | The role of rumination in depressive disorders and mixed anxiety/depressive symptoms. | S Nolen-Hoeksema | J Abnorm Psychol | 2000 | 11016119 | Yes |
3450 | 1114 | 1114.0 | 19.88 | 19.9 | NFAT proteins: key regulators of T-cell development and function. | Fernando Macian | Nat Rev Immunol | 2005 | 15928679 | No |
3451 | 3342 | 1114.0 | 80.99 | 27.0 | Mechanisms linking obesity to insulin resistance and type 2 diabetes. | Steven E Kahn, Rebecca L Hull, Kristina M Utzschneider | Nature | 2006 | 17167471 | No |
3452 | 2227 | 1113.5 | 34.45 | 17.2 | Construction of phylogenetic trees. | W M Fitch, E Margoliash | Science | 1967 | 5334057 | No |
3453 | 2226 | 1113.0 | 58.8 | 29.4 | Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. | R A Ignotz, J Massagué | J Biol Chem | 1986 | 3456347 | Yes |
3454 | 2226 | 1113.0 | 44.79 | 22.4 | RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. | M B Shapiro, P Senapathy | Nucleic Acids Res | 1987 | 3658675 | Yes |
3455 | 1113 | 1113.0 | 28.03 | 28.0 | Sex-hormone-binding globulin. | D C Anderson | Clin Endocrinol (Oxf) | 1974 | 4134992 | No |
3456 | 1113 | 1113.0 | 28.75 | 28.8 | Comprehensive observational assessment: Ia. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse. | S Irwin | Psychopharmacologia | 1968 | 5679627 | Yes |
3457 | 1113 | 1113.0 | 25.24 | 25.2 | Viruses in the sea. | Curtis A Suttle | Nature | 2005 | 16163346 | No |
3458 | 1113 | 1113.0 | 27.6 | 27.6 | Immortal time bias in pharmaco-epidemiology. | Samy Suissa | Am J Epidemiol | 2008 | 18056625 | No |
3459 | 11121 | 1112.1 | 252.88 | 25.3 | Scalable molecular dynamics with NAMD. | James C Phillips, Rosemary Braun, Wei Wang, James Gumbart, Emad Tajkhorshid, Elizabeth Villa, Christophe Chipot, Robert D Skeel, Laxmikant Kalé, Klaus Schulten | J Comput Chem | 2005 | 16222654 | Yes |
3460 | 1112 | 1112.0 | 39.36 | 39.4 | Epidemiological synergy. Interrelationships between human immunodeficiency virus infection and other sexually transmitted diseases. | J N Wasserheit | Sex Transm Dis | 1992 | 1595015 | No |
3461 | 1112 | 1112.0 | 32.92 | 32.9 | Plasmid complements of Streptococcus lactis NCDO 712 and other lactic streptococci after protoplast-induced curing. | M J Gasson | J Bacteriol | 1983 | 6403500 | Yes |
3462 | 4448 | 1112.0 | 116.88 | 29.2 | Prevalence and trends in obesity among US adults, 1999-2000. | Katherine M Flegal, Margaret D Carroll, Cynthia L Ogden, Clifford L Johnson | JAMA | 2002 | 12365955 | Yes |
3463 | 1112 | 1112.0 | 0.0 | 0.0 | A cytoarchitectonic atlas of the spinal cord in the cat. | B Rexed | J Comp Neurol | 1954 | 13163236 | Yes |
3464 | 2224 | 1112.0 | 0.0 | 0.0 | Localization of antigen in tissue cells; improvements in a method for the detection of antigen by means of fluorescent antibody. | A H Coons, M H Kaplan | J Exp Med | 1950 | 15395569 | Yes |
3465 | 1112 | 1112.0 | 0.0 | 0.0 | The Stability of Broken Ends of Chromosomes in Zea Mays. | B McClintock | Genetics | 1941 | 17247004 | Yes |
3466 | 2223 | 1111.5 | 45.58 | 22.8 | Genomic control for association studies. | B Devlin, K Roeder | Biometrics | 1999 | 11315092 | Yes |
3467 | 2223 | 1111.5 | 60.56 | 30.3 | Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis. | J A Sterne, M Egger | J Clin Epidemiol | 2001 | 11576817 | Yes |
3468 | 2221 | 1110.5 | 71.02 | 35.5 | Mechanisms of fibrosis: therapeutic translation for fibrotic disease. | Thomas A Wynn, Thirumalai R Ramalingam | Nat Med | 2012 | 22772564 | No |
3469 | 3330 | 1110.0 | 66.21 | 22.1 | SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. | Jay D Horton, Joseph L Goldstein, Michael S Brown | J Clin Invest | 2002 | 11994399 | No |
3470 | 2220 | 1110.0 | 47.53 | 23.8 | Roles of CHOP/GADD153 in endoplasmic reticulum stress. | S Oyadomari, M Mori | Cell Death Differ | 2004 | 14685163 | No |
3471 | 2219 | 1109.5 | 71.58 | 35.8 | Wine, alcohol, platelets, and the French paradox for coronary heart disease. | S Renaud, M de Lorgeril | Lancet | 1992 | 1351198 | Yes |
3472 | 4438 | 1109.5 | 24.38 | 6.1 | The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. | P J Randle, P B Garland, C N Hales, E A Newsholme | Lancet | 1963 | 13990765 | Yes |
3473 | 2219 | 1109.5 | 54.18 | 27.1 | Adipocytokines: mediators linking adipose tissue, inflammation and immunity. | Herbert Tilg, Alexander R Moschen | Nat Rev Immunol | 2006 | 16998510 | No |
3474 | 2218 | 1109.0 | 90.69 | 45.3 | Tripartite model of anxiety and depression: psychometric evidence and taxonomic implications. | L A Clark, D Watson | J Abnorm Psychol | 1991 | 1918611 | No |
3475 | 1109 | 1109.0 | 26.43 | 26.4 | Quantification of beta-sheet amyloid fibril structures with thioflavin T. | H LeVine | Methods Enzymol | 1999 | 10507030 | Yes |
3476 | 1109 | 1109.0 | 21.07 | 21.1 | Focal adhesion kinase: the first ten years. | J Thomas Parsons | J Cell Sci | 2003 | 12640026 | No |
3477 | 1109 | 1109.0 | 25.68 | 25.7 | Anatomy and regulation of the central melanocortin system. | Roger D Cone | Nat Neurosci | 2005 | 15856065 | No |
3478 | 3326 | 1108.7 | 112.97 | 37.7 | Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides. | M Hamberg, J Svensson, B Samuelsson | Proc Natl Acad Sci U S A | 1975 | 1059088 | Yes |
3479 | 2216 | 1108.0 | 51.95 | 26.0 | Cellular uptake of the tat protein from human immunodeficiency virus. | A D Frankel, C O Pabo | Cell | 1988 | 2849510 | Yes |
3480 | 1108 | 1108.0 | 24.53 | 24.5 | The molecular biology of leukocyte chemoattractant receptors. | P M Murphy | Annu Rev Immunol | 1994 | 8011292 | No |
3481 | 1108 | 1108.0 | 24.15 | 24.1 | Toward self-organization and complex matter. | Jean-Marie Lehn | Science | 2002 | 11923524 | Yes |
3482 | 2215 | 1107.5 | 52.87 | 26.4 | Reducing the dimensionality of data with neural networks. | G E Hinton, R R Salakhutdinov | Science | 2006 | 16873662 | Yes |
3483 | 1107 | 1107.0 | 22.29 | 22.3 | Primary response genes induced by growth factors and tumor promoters. | H R Herschman | Annu Rev Biochem | 1991 | 1883198 | No |
3484 | 1107 | 1107.0 | 33.64 | 33.6 | Inferring microstructural features and the physiological state of tissues from diffusion-weighted images. | P J Basser | NMR Biomed | 1995 | 8739270 | No |
3485 | 2214 | 1107.0 | 49.35 | 24.7 | Synaptic activity and the construction of cortical circuits. | L C Katz, C J Shatz | Science | 1996 | 8895456 | No |
3486 | 1107 | 1107.0 | 23.59 | 23.6 | VEGF as a key mediator of angiogenesis in cancer. | Peter Carmeliet | Oncology | 2005 | 16301830 | No |
3487 | 2214 | 1107.0 | 63.82 | 31.9 | Relaxing the rule of ten events per variable in logistic and Cox regression. | Eric Vittinghoff, Charles E McCulloch | Am J Epidemiol | 2007 | 17182981 | Yes |
3488 | 2213 | 1106.5 | 82.46 | 41.2 | Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes. | I B Wilson, P D Cleary | JAMA | 1995 | 7996652 | Yes |
3489 | 1106 | 1106.0 | 23.24 | 23.2 | A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor. | J Milbrandt | Science | 1987 | 3672127 | Yes |
3490 | 1106 | 1106.0 | 26.13 | 26.1 | Cells in stress: transcriptional activation of heat shock genes. | R I Morimoto | Science | 1993 | 8451637 | No |
3491 | 1106 | 1106.0 | 26.07 | 26.1 | Differential projections of the infralimbic and prelimbic cortex in the rat. | Robert P Vertes | Synapse | 2004 | 14579424 | Yes |
3492 | 1106 | 1106.0 | 32.77 | 32.8 | Cognitive and affective development in adolescence. | Laurence Steinberg | Trends Cogn Sci | 2005 | 15668099 | No |
3493 | 1106 | 1106.0 | 22.04 | 22.0 | Models, mechanisms and clinical evidence for cancer dormancy. | Julio A Aguirre-Ghiso | Nat Rev Cancer | 2007 | 17957189 | No |
3494 | 1106 | 1106.0 | 25.74 | 25.7 | Solid-state nanopores. | Cees Dekker | Nat Nanotechnol | 2007 | 18654264 | No |
3495 | 1106 | 1106.0 | 40.11 | 40.1 | Visual attention: the past 25 years. | Marisa Carrasco | Vision Res | 2011 | 21549742 | No |
3496 | 1105 | 1105.0 | 27.77 | 27.8 | Avidin. | N M Green | Adv Protein Chem | 1975 | 237414 | Yes |
3497 | 1105 | 1105.0 | 27.18 | 27.2 | The synthesis of complex carbohydrates by multiglycosyltransferase systems and their potential function in intercellular adhesion. | S Roseman | Chem Phys Lipids | 1970 | 5476326 | Yes |
3498 | 3315 | 1105.0 | 91.78 | 30.6 | Spirometric reference values from a sample of the general U.S. population. | J L Hankinson, J R Odencrantz, K B Fedan | Am J Respir Crit Care Med | 1999 | 9872837 | Yes |
3499 | 2209 | 1104.5 | 0.0 | 0.0 | Cortisone in ulcerative colitis; final report on a therapeutic trial. | S C Truelove, L J Witts | Br Med J | 1955 | 13260656 | Yes |
3500 | 1104 | 1104.0 | 30.8 | 30.8 | On the utility of P3 amplitude as a measure of processing capacity. | A Kok | Psychophysiology | 2001 | 11352145 | No |
3501 | 1104 | 1104.0 | 24.36 | 24.4 | Lithium batteries and cathode materials. | M Stanley Whittingham | Chem Rev | 2004 | 15669156 | Yes |
3502 | 2208 | 1104.0 | 50.98 | 25.5 | The host defense of Drosophila melanogaster. | Bruno Lemaitre, Jules Hoffmann | Annu Rev Immunol | 2007 | 17201680 | No |
3503 | 1104 | 1104.0 | 45.39 | 45.4 | How does sexual minority stigma "get under the skin"? A psychological mediation framework. | Mark L Hatzenbuehler | Psychol Bull | 2009 | 19702379 | No |
3504 | 2208 | 1104.0 | 65.28 | 32.6 | Chronic hepatitis B: update 2009. | Anna S F Lok, Brian J McMahon | Hepatology | 2009 | 19714720 | Yes |
3505 | 1104 | 1104.0 | 37.57 | 37.6 | Globalization of diabetes: the role of diet, lifestyle, and genes. | Frank B Hu | Diabetes Care | 2011 | 21617109 | No |
3506 | 2207 | 1103.5 | 95.42 | 47.7 | Moving towards best practice when using inverse probability of treatment weighting (IPTW) using the propensity score to estimate causal treatment effects in observational studies. | Peter C Austin, Elizabeth A Stuart | Stat Med | 2015 | 26238958 | No |
3507 | 6619 | 1103.2 | 173.02 | 28.8 | Prediction of coronary heart disease using risk factor categories. | P W Wilson, R B D'Agostino, D Levy, A M Belanger, H Silbershatz, W B Kannel | Circulation | 1998 | 9603539 | Yes |
3508 | 1103 | 1103.0 | 30.07 | 30.1 | Testicular biopsy score count--a method for registration of spermatogenesis in human testes: normal values and results in 335 hypogonadal males. | S G Johnsen | Hormones | 1970 | 5527187 | Yes |
3509 | 1103 | 1103.0 | 27.42 | 27.4 | The Trk family of neurotrophin receptors. | M Barbacid | J Neurobiol | 1994 | 7852993 | No |
3510 | 1103 | 1103.0 | 21.41 | 21.4 | Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. | A S Baldwin | J Clin Invest | 2001 | 11160144 | No |
3511 | 2206 | 1103.0 | 58.39 | 29.2 | Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance. | I Chopra, M Roberts | Microbiol Mol Biol Rev | 2001 | 11381101 | Yes |
3512 | 1103 | 1103.0 | 24.7 | 24.7 | Current concepts of the pathogenesis of the acute coronary syndromes. | P Libby | Circulation | 2001 | 11457759 | No |
3513 | 2206 | 1103.0 | 27.69 | 13.8 | Demonstration Of Tumor-Specific Antigens In Human Colonic Carcinomata By Immunological Tolerance And Absorption Techniques. | P Gold, S O Freedman | J Exp Med | 1965 | 14270243 | Yes |
3514 | 1103 | 1103.0 | 22.84 | 22.8 | Membrane recognition by phospholipid-binding domains. | Mark A Lemmon | Nat Rev Mol Cell Biol | 2008 | 18216767 | No |
3515 | 3308 | 1102.7 | 94.66 | 31.6 | Interpretation of changes in health-related quality of life: the remarkable universality of half a standard deviation. | Geoffrey R Norman, Jeff A Sloan, Kathleen W Wyrwich | Med Care | 2003 | 12719681 | No |
3516 | 2205 | 1102.5 | 50.15 | 25.1 | A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. | J N Cohn, G Tognoni | N Engl J Med | 2001 | 11759645 | Yes |
3517 | 2205 | 1102.5 | 67.1 | 33.5 | Reactive oxygen species, cellular redox systems, and apoptosis. | Magdalena L Circu, Tak Yee Aw | Free Radic Biol Med | 2010 | 20045723 | No |
3518 | 1102 | 1102.0 | 51.13 | 51.1 | Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase. | Y Kono | Arch Biochem Biophys | 1978 | 24422 | Yes |
3519 | 1102 | 1102.0 | 42.35 | 42.4 | The role of endothelium in the responses of vascular smooth muscle to drugs. | R F Furchgott | Annu Rev Pharmacol Toxicol | 1984 | 6203480 | No |
3520 | 4408 | 1102.0 | 149.07 | 37.3 | Prevalence and trends in obesity among US adults, 1999-2008. | Katherine M Flegal, Margaret D Carroll, Cynthia L Ogden, Lester R Curtin | JAMA | 2010 | 20071471 | Yes |
3521 | 7708 | 1101.1 | 239.72 | 34.2 | Toxicity and response criteria of the Eastern Cooperative Oncology Group. | M M Oken, R H Creech, D C Tormey, J Horton, T E Davis, E T McFadden, P P Carbone | Am J Clin Oncol | 1982 | 7165009 | Yes |
3522 | 1101 | 1101.0 | 39.63 | 39.6 | Methods for dealing with reaction time outliers. | R Ratcliff | Psychol Bull | 1993 | 8272468 | Yes |
3523 | 1101 | 1101.0 | 29.03 | 29.0 | Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity. | F P Guengerich | Chem Res Toxicol | 2001 | 11409933 | No |
3524 | 1101 | 1101.0 | 22.42 | 22.4 | Osmotic stress signaling and osmoadaptation in yeasts. | Stefan Hohmann | Microbiol Mol Biol Rev | 2002 | 12040128 | No |
3525 | 1101 | 1101.0 | 23.01 | 23.0 | Phenotypic plasticity and the epigenetics of human disease. | Andrew P Feinberg | Nature | 2007 | 17522677 | No |
3526 | 1101 | 1101.0 | 0.0 | 0.0 | Quantitative Determination of Carbohydrates With Dreywood's Anthrone Reagent. | D L Morris | Science | 1948 | 17814729 | Yes |
3527 | 1101 | 1101.0 | 28.31 | 28.3 | Ovarian cancer development and metastasis. | Ernst Lengyel | Am J Pathol | 2010 | 20651229 | Yes |
3528 | 2202 | 1101.0 | 156.09 | 78.0 | OrthoFinder: phylogenetic orthology inference for comparative genomics. | David M Emms, Steven Kelly | Genome Biol | 2019 | 31727128 | Yes |
3529 | 5502 | 1100.4 | 305.78 | 61.2 | ModelFinder: fast model selection for accurate phylogenetic estimates. | Subha Kalyaanamoorthy, Bui Quang Minh, Thomas K F Wong, Arndt von Haeseler, Lars S Jermiin | Nat Methods | 2017 | 28481363 | Yes |
3530 | 1100 | 1100.0 | 23.02 | 23.0 | T-lymphocyte recognition of antigen in association with gene products of the major histocompatibility complex. | R H Schwartz | Annu Rev Immunol | 1985 | 2415139 | No |
3531 | 2199 | 1099.5 | 51.81 | 25.9 | T antigen is bound to a host protein in SV40-transformed cells. | D P Lane, L V Crawford | Nature | 1979 | 218111 | Yes |
3532 | 2199 | 1099.5 | 63.51 | 31.8 | The acute phase response. | H Baumann, J Gauldie | Immunol Today | 1994 | 7512342 | No |
3533 | 6597 | 1099.5 | 143.22 | 23.9 | Obesity is associated with macrophage accumulation in adipose tissue. | Stuart P Weisberg, Daniel McCann, Manisha Desai, Michael Rosenbaum, Rudolph L Leibel, Anthony W Ferrante | J Clin Invest | 2003 | 14679176 | Yes |
3534 | 1099 | 1099.0 | 33.42 | 33.4 | Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. | D L Coleman | Diabetologia | 1978 | 350680 | No |
3535 | 1099 | 1099.0 | 55.33 | 55.3 | Osseointegration and its experimental background. | P I Brånemark | J Prosthet Dent | 1983 | 6352924 | No |
3536 | 1099 | 1099.0 | 29.91 | 29.9 | Aging, energy, and oxidative stress in neurodegenerative diseases. | M F Beal | Ann Neurol | 1995 | 7668820 | No |
3537 | 2198 | 1099.0 | 49.07 | 24.5 | Cell cycle control and cancer. | L H Hartwell, M B Kastan | Science | 1994 | 7997877 | No |
3538 | 1099 | 1099.0 | 28.14 | 28.1 | Neuropathology of Parkinson's disease. | L S Forno | J Neuropathol Exp Neurol | 1996 | 8786384 | No |
3539 | 1099 | 1099.0 | 36.09 | 36.1 | Socioeconomic disadvantage and child development. | V C McLoyd | Am Psychol | 1998 | 9491747 | No |
3540 | 2198 | 1099.0 | 38.17 | 19.1 | A synthetic oscillatory network of transcriptional regulators. | M B Elowitz, S Leibler | Nature | 2000 | 10659856 | Yes |
3541 | 1099 | 1099.0 | 24.2 | 24.2 | Personal genomes: The case of the missing heritability. | Brendan Maher | Nature | 2008 | 18987709 | No |
3542 | 2198 | 1099.0 | 70.3 | 35.1 | Central sensitization: a generator of pain hypersensitivity by central neural plasticity. | Alban Latremoliere, Clifford J Woolf | J Pain | 2009 | 19712899 | No |
3543 | 1098 | 1098.0 | 18.86 | 18.9 | Cell lines derived from late embryonic stages of Drosophila melanogaster. | I Schneider | J Embryol Exp Morphol | 1972 | 4625067 | Yes |
3544 | 1098 | 1098.0 | 19.59 | 19.6 | Time-dependent processes in memory storage. | J L McGaugh | Science | 1966 | 5917768 | Yes |
3545 | 1098 | 1098.0 | 39.87 | 39.9 | Relativistic electronic-structure calculations employing a two-component no-pair formalism with external-field projection operators. | B A Hess | Phys Rev A Gen Phys | 1986 | 9897114 | Yes |
3546 | 1098 | 1098.0 | 0.0 | 0.0 | Cleavage of the haem-protein link by acid methylethylketone. | F W Teale | Biochim Biophys Acta | 1959 | 13837237 | Yes |
3547 | 1098 | 1098.0 | 46.59 | 46.6 | CONSORT-EHEALTH: improving and standardizing evaluation reports of Web-based and mobile health interventions. | Gunther Eysenbach | J Med Internet Res | 2011 | 22209829 | No |
3548 | 2196 | 1098.0 | 85.46 | 42.7 | Long Noncoding RNAs in Cancer Pathways. | Adam M Schmitt, Howard Y Chang | Cancer Cell | 2016 | 27070700 | No |
3549 | 2196 | 1098.0 | 105.32 | 52.7 | Functional Classification and Experimental Dissection of Long Noncoding RNAs. | Florian Kopp, Joshua T Mendell | Cell | 2018 | 29373828 | No |
3550 | 2195 | 1097.5 | 45.44 | 22.7 | p53: puzzle and paradigm. | L J Ko, C Prives | Genes Dev | 1996 | 8654922 | No |
3551 | 1097 | 1097.0 | 20.27 | 20.3 | Chronic myeloid leukemia. | C L Sawyers | N Engl J Med | 1999 | 10219069 | No |
3552 | 1097 | 1097.0 | 27.34 | 27.3 | Pathogenesis of osteoporosis: concepts, conflicts, and prospects. | Lawrence G Raisz | J Clin Invest | 2005 | 16322775 | No |
3553 | 3291 | 1097.0 | 177.45 | 59.1 | Hepatocellular carcinoma. | Alejandro Forner, María Reig, Jordi Bruix | Lancet | 2018 | 29307467 | No |
3554 | 1096 | 1096.0 | 19.01 | 19.0 | Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast. | R Rothstein | Methods Enzymol | 1991 | 2005793 | Yes |
3555 | 2192 | 1096.0 | 65.66 | 32.8 | 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. | A Poland, J C Knutson | Annu Rev Pharmacol Toxicol | 1982 | 6282188 | No |
3556 | 3288 | 1096.0 | 102.28 | 34.1 | PedsQL 4.0: reliability and validity of the Pediatric Quality of Life Inventory version 4.0 generic core scales in healthy and patient populations. | J W Varni, M Seid, P S Kurtin | Med Care | 2001 | 11468499 | Yes |
3557 | 2191 | 1095.5 | 57.81 | 28.9 | Localized surface plasmon resonance spectroscopy and sensing. | Katherine A Willets, Richard P Van Duyne | Annu Rev Phys Chem | 2007 | 17067281 | No |
3558 | 1095 | 1095.0 | 20.74 | 20.7 | Luciferase reporter gene vectors for analysis of promoters and enhancers. | S K Nordeen | Biotechniques | 1988 | 2908509 | Yes |
3559 | 1095 | 1095.0 | 22.42 | 22.4 | mRNA stability in mammalian cells. | J Ross | Microbiol Rev | 1995 | 7565413 | No |
3560 | 1095 | 1095.0 | 28.03 | 28.0 | Glutathione and its role in cellular functions. | H Sies | Free Radic Biol Med | 1999 | 10569624 | No |
3561 | 1095 | 1095.0 | 27.08 | 27.1 | Seed Germination and Dormancy. | J. D. Bewley | Plant Cell | 1997 | 12237375 | Yes |
3562 | 1095 | 1095.0 | 0.0 | 0.0 | The purine and pyrimidine composition of deoxypentose nucleic acids. | G R Wyatt | Biochem J | 1951 | 14838906 | Yes |
3563 | 1095 | 1095.0 | 32.79 | 32.8 | Social support and patient adherence to medical treatment: a meta-analysis. | M Robin DiMatteo | Health Psychol | 2004 | 15008666 | Yes |
3564 | 2190 | 1095.0 | 74.59 | 37.3 | The complexity of NF-κB signaling in inflammation and cancer. | Bastian Hoesel, Johannes A Schmid | Mol Cancer | 2013 | 23915189 | No |
3565 | 1094 | 1094.0 | 38.58 | 38.6 | Spin trapping: ESR parameters of spin adducts. | G R Buettner | Free Radic Biol Med | 1987 | 2826304 | No |
3566 | 1094 | 1094.0 | 27.69 | 27.7 | Two distinct classes of carbohydrate-recognition domains in animal lectins. | K Drickamer | J Biol Chem | 1988 | 3290208 | No |
3567 | 1094 | 1094.0 | 32.64 | 32.6 | Tests for emotionality in rats and mice: a review. | J Archer | Anim Behav | 1973 | 4578750 | No |
3568 | 2188 | 1094.0 | 77.58 | 38.8 | Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry. | A I Basbaum, H L Fields | Annu Rev Neurosci | 1984 | 6143527 | No |
3569 | 1094 | 1094.0 | 25.19 | 25.2 | The prefrontal cortex--an update: time is of the essence. | J M Fuster | Neuron | 2001 | 11394996 | No |
3570 | 2187 | 1093.5 | 45.72 | 22.9 | The Hsp70 and Hsp60 chaperone machines. | B Bukau, A L Horwich | Cell | 1998 | 9476895 | No |
3571 | 2187 | 1093.5 | 0.0 | 0.0 | Micromethod for the direct determination of serum triglycerides. | E Van Handel, D B Zilversmit | J Lab Clin Med | 1957 | 13439279 | Yes |
3572 | 2187 | 1093.5 | 53.7 | 26.9 | Quorum sensing: cell-to-cell communication in bacteria. | Christopher M Waters, Bonnie L Bassler | Annu Rev Cell Dev Biol | 2005 | 16212498 | No |
3573 | 3280 | 1093.3 | 75.93 | 25.3 | Obesity induces a phenotypic switch in adipose tissue macrophage polarization. | Carey N Lumeng, Jennifer L Bodzin, Alan R Saltiel | J Clin Invest | 2007 | 17200717 | Yes |
3574 | 1093 | 1093.0 | 27.7 | 27.7 | Selectins: interpreters of cell-specific carbohydrate information during inflammation. | L A Lasky | Science | 1992 | 1439808 | No |
3575 | 1093 | 1093.0 | 29.5 | 29.5 | A kinetic photometric method for serum gamma-glutamyl transpeptidase. | G Szasz | Clin Chem | 1969 | 5773262 | Yes |
3576 | 1093 | 1093.0 | 32.29 | 32.3 | Spatially heterogeneous dynamics in supercooled liquids. | M D Ediger | Annu Rev Phys Chem | 2000 | 11031277 | Yes |
3577 | 1093 | 1093.0 | 0.0 | 0.0 | Motivation reconsidered: the concept of competence. | R W White | Psychol Rev | 1959 | 13844397 | Yes |
3578 | 1093 | 1093.0 | 25.96 | 26.0 | Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. | Thomas A Wynn | J Clin Invest | 2007 | 17332879 | No |
3579 | 3278 | 1092.7 | 98.07 | 32.7 | Depression: a new animal model sensitive to antidepressant treatments. | R D Porsolt, M Le Pichon, M Jalfre | Nature | 1977 | 559941 | Yes |
3580 | 2184 | 1092.0 | 80.07 | 40.0 | The Modified Mini-Mental State (3MS) examination. | E L Teng, H C Chui | J Clin Psychiatry | 1987 | 3611032 | Yes |
3581 | 1092 | 1092.0 | 42.96 | 43.0 | Corticosteroids and lymphoid cells. | H N Claman | N Engl J Med | 1972 | 5043524 | Yes |
3582 | 1092 | 1092.0 | 33.98 | 34.0 | The oxidation hypothesis of atherosclerosis. | J L Witztum | Lancet | 1994 | 7916078 | No |
3583 | 5460 | 1092.0 | 114.98 | 23.0 | The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. | J W Harper, G R Adami, N Wei, K Keyomarsi, S J Elledge | Cell | 1993 | 8242751 | Yes |
3584 | 2184 | 1092.0 | 47.93 | 24.0 | Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. | Daniel J Hicklin, Lee M Ellis | J Clin Oncol | 2005 | 15585754 | No |
3585 | 1090 | 1090.0 | 23.05 | 23.1 | Twilight zone of protein sequence alignments. | B Rost | Protein Eng | 1999 | 10195279 | Yes |
3586 | 2180 | 1090.0 | 43.67 | 21.8 | Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm. | P E Wright, H J Dyson | J Mol Biol | 1999 | 10550212 | No |
3587 | 2180 | 1090.0 | 50.21 | 25.1 | Hepatitis C virus infection. | G M Lauer, B D Walker | N Engl J Med | 2001 | 11439948 | No |
3588 | 1090 | 1090.0 | 25.2 | 25.2 | P-450 metabolites of arachidonic acid in the control of cardiovascular function. | Richard J Roman | Physiol Rev | 2002 | 11773611 | No |
3589 | 1090 | 1090.0 | 29.96 | 30.0 | Cholinesterase inhibitors for Alzheimer's disease. | J Birks | Cochrane Database Syst Rev | 2006 | 16437532 | No |
3590 | 2180 | 1090.0 | 64.26 | 32.1 | Are the dorsal and ventral hippocampus functionally distinct structures? | Michael S Fanselow, Hong-Wei Dong | Neuron | 2010 | 20152109 | No |
3591 | 1090 | 1090.0 | 46.35 | 46.4 | A comprehensive review on metabolic syndrome. | Jaspinder Kaur | Cardiol Res Pract | 2014 | 24711954 | No |
3592 | 2179 | 1089.5 | 68.52 | 34.3 | Glutamate and the pathophysiology of hypoxic--ischemic brain damage. | S M Rothman, J W Olney | Ann Neurol | 1986 | 2421636 | No |
3593 | 2179 | 1089.5 | 60.97 | 30.5 | Burden of major musculoskeletal conditions. | Anthony D Woolf, Bruce Pfleger | Bull World Health Organ | 2003 | 14710506 | No |
3594 | 5445 | 1089.0 | 164.6 | 32.9 | Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. | Salim Yusuf, Bertram Pitt, Clarence E Davis, William B Hood, Jay N Cohn | N Engl J Med | 1991 | 2057034 | Yes |
3595 | 1089 | 1089.0 | 19.71 | 19.7 | Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. | R A Frye | Biochem Biophys Res Commun | 2000 | 10873683 | Yes |
3596 | 1089 | 1089.0 | 0.0 | 0.0 | Aniline hydrogen phthalate as a spraying reagent for chromatography of sugars. | S M Partridge | Nature | 1949 | 18140444 | Yes |
3597 | 2177 | 1088.5 | 74.31 | 37.2 | Consensus methods for medical and health services research. | J Jones, D Hunter | BMJ | 1995 | 7640549 | No |
3598 | 2177 | 1088.5 | 83.3 | 41.6 | The Posttraumatic Growth Inventory: measuring the positive legacy of trauma. | R G Tedeschi, L G Calhoun | J Trauma Stress | 1996 | 8827649 | Yes |
3599 | 2176 | 1088.0 | 81.81 | 40.9 | Understanding face recognition. | V Bruce, A Young | Br J Psychol | 1986 | 3756376 | Yes |
3600 | 1088 | 1088.0 | 24.64 | 24.6 | Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes: a proposal for a synonymous codon choice that is optimal for the E. coli translational system. | T Ikemura | J Mol Biol | 1981 | 6175758 | Yes |
3601 | 1088 | 1088.0 | 0.0 | 0.0 | Asymptomatic infections of the urinary tract. | E H Kass | Trans Assoc Am Physicians | 1956 | 13380946 | Yes |
3602 | 1088 | 1088.0 | 7.82 | 7.8 | Cardiac nucleotides in hypoxia: possible role in regulation of coronary blood flow. | R M Berne | Am J Physiol | 1963 | 13971060 | Yes |
3603 | 6525 | 1087.5 | 159.43 | 26.6 | Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. | S Yusuf, P Sleight, J Pogue, J Bosch, R Davies, G Dagenais | N Engl J Med | 2000 | 10639539 | Yes |
3604 | 1087 | 1087.0 | 26.63 | 26.6 | DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability. | J F Ward | Prog Nucleic Acid Res Mol Biol | 1988 | 3065826 | No |
3605 | 1087 | 1087.0 | 27.59 | 27.6 | Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol. | M J Berridge | Biochem J | 1983 | 6309155 | Yes |
3606 | 1087 | 1087.0 | 25.25 | 25.2 | BIONJ: an improved version of the NJ algorithm based on a simple model of sequence data. | O Gascuel | Mol Biol Evol | 1997 | 9254330 | Yes |
3607 | 1087 | 1087.0 | 25.46 | 25.5 | Perylene bisimide dyes as versatile building blocks for functional supramolecular architectures. | Frank Würthner | Chem Commun (Camb) | 2004 | 15263926 | Yes |
3608 | 2173 | 1086.5 | 81.85 | 40.9 | Visual search and stimulus similarity. | J Duncan, G W Humphreys | Psychol Rev | 1989 | 2756067 | Yes |
3609 | 1086 | 1086.0 | 30.83 | 30.8 | Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are onco-developmental antigens. | T Feizi | Nature | 1985 | 2579340 | Yes |
3610 | 2172 | 1086.0 | 50.96 | 25.5 | Peroxidase-labeled antibody. A new method of conjugation. | P K Nakane, A Kawaoi | J Histochem Cytochem | 1974 | 4443551 | Yes |
3611 | 1086 | 1086.0 | 25.14 | 25.1 | Selectins and their ligands: current concepts and controversies. | G S Kansas | Blood | 1996 | 8896391 | No |
3612 | 1086 | 1086.0 | 23.88 | 23.9 | Molecular mechanisms of myocardial remodeling. | B Swynghedauw | Physiol Rev | 1999 | 9922372 | No |
3613 | 1086 | 1086.0 | 23.28 | 23.3 | Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology. | Michael Forgac | Nat Rev Mol Cell Biol | 2007 | 17912264 | No |
3614 | 2171 | 1085.5 | 0.0 | 0.0 | A revision of the Schoenheimer-Sperry method for cholesterol determination. | W M Sperry, M Webb | J Biol Chem | 1950 | 14794694 | Yes |
3615 | 6511 | 1085.2 | 167.54 | 27.9 | The capsaicin receptor: a heat-activated ion channel in the pain pathway. | M J Caterina, M A Schumacher, M Tominaga, T A Rosen, J D Levine, D Julius | Nature | 1997 | 9349813 | Yes |
3616 | 1085 | 1085.0 | 37.3 | 37.3 | Multiple organ failure. Pathophysiology and potential future therapy. | E A Deitch | Ann Surg | 1992 | 1503516 | No |
3617 | 1085 | 1085.0 | 54.77 | 54.8 | The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): a clinical investigation of 225 patients using ambulatory 24-hour pH monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury. | J A Koufman | Laryngoscope | 1991 | 1895864 | No |
3618 | 1085 | 1085.0 | 42.42 | 42.4 | A simple method for determination of serum catalase activity and revision of reference range. | L Góth | Clin Chim Acta | 1991 | 2029780 | Yes |
3619 | 1085 | 1085.0 | 20.56 | 20.6 | At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells. | M Kozak | J Mol Biol | 1987 | 3681984 | Yes |
3620 | 1085 | 1085.0 | 0.0 | 0.0 | The concentration of sympathin in different parts of the central nervous system under normal conditions and after the administration of drugs. | M Vogt | J Physiol | 1954 | 13152692 | Yes |
3621 | 2169 | 1084.5 | 67.08 | 33.5 | Mental rotation of three-dimensional objects. | R N Shepard, J Metzler | Science | 1971 | 5540314 | Yes |
3622 | 2168 | 1084.0 | 75.22 | 37.6 | A formula to estimate the approximate surface area if height and weight be known. 1916. | D Du Bois, E F Du Bois | Nutrition | 1989 | 2520314 | No |
3623 | 1084 | 1084.0 | 30.51 | 30.5 | Limbic-cortical dysregulation: a proposed model of depression. | H S Mayberg | J Neuropsychiatry Clin Neurosci | 1997 | 9276848 | No |
3624 | 1084 | 1084.0 | 20.41 | 20.4 | Progress in human tumour immunology and immunotherapy. | S A Rosenberg | Nature | 2001 | 11357146 | No |
3625 | 1084 | 1084.0 | 28.64 | 28.6 | Abiotic stress, the field environment and stress combination. | Ron Mittler | Trends Plant Sci | 2006 | 16359910 | No |
3626 | 4336 | 1084.0 | 207.77 | 51.9 | Genome sequence-based species delimitation with confidence intervals and improved distance functions. | Jan P Meier-Kolthoff, Alexander F Auch, Hans-Peter Klenk, Markus Göker | BMC Bioinformatics | 2013 | 23432962 | Yes |
3627 | 2166 | 1083.0 | 47.19 | 23.6 | Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age. | T Hunter, J Pines | Cell | 1994 | 7954824 | No |
3628 | 1083 | 1083.0 | 21.45 | 21.4 | Coiled coils: new structures and new functions. | A Lupas | Trends Biochem Sci | 1996 | 8918191 | No |
3629 | 1083 | 1083.0 | 23.76 | 23.8 | New ideas about atrial fibrillation 50 years on. | Stanley Nattel | Nature | 2002 | 11805846 | No |
3630 | 1083 | 1083.0 | 0.0 | 0.0 | The stereotaxic method and radiosurgery of the brain. | L Leksell | Acta Chir Scand | 1951 | 14914373 | Yes |
3631 | 2166 | 1083.0 | 75.96 | 38.0 | A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation. | Walter J Paulus, Carsten Tschöpe | J Am Coll Cardiol | 2013 | 23684677 | No |
3632 | 2165 | 1082.5 | 60.61 | 30.3 | ASCORBATE AND GLUTATHIONE: Keeping Active Oxygen Under Control. | Graham Noctor, Christine H. Foyer | Annu Rev Plant Physiol Plant Mol Biol | 1998 | 15012235 | Yes |
3633 | 1082 | 1082.0 | 58.07 | 58.1 | The stabilizing system of the spine. Part I. Function, dysfunction, adaptation, and enhancement. | M M Panjabi | J Spinal Disord | 1992 | 1490034 | Yes |
3634 | 1082 | 1082.0 | 56.15 | 56.1 | The tension-stress effect on the genesis and growth of tissues: Part II. The influence of the rate and frequency of distraction. | G A Ilizarov | Clin Orthop Relat Res | 1989 | 2912628 | Yes |
3635 | 1082 | 1082.0 | 41.63 | 41.6 | A new international staging system for lung cancer. | C F Mountain | Chest | 1986 | 3514171 | No |
3636 | 1082 | 1082.0 | 30.24 | 30.2 | Transport of molecules in the tumor interstitium: a review. | R K Jain | Cancer Res | 1987 | 3555767 | No |
3637 | 1082 | 1082.0 | 32.48 | 32.5 | A teacher rating scale for use in drug studies with children. | C K Conners | Am J Psychiatry | 1969 | 4900822 | Yes |
3638 | 1082 | 1082.0 | 23.25 | 23.2 | PHD: predicting one-dimensional protein structure by profile-based neural networks. | B Rost | Methods Enzymol | 1996 | 8743704 | Yes |
3639 | 1082 | 1082.0 | 27.69 | 27.7 | Unequal treatment: confronting racial and ethnic disparities in health care. | Alan Nelson | J Natl Med Assoc | 2002 | 12152921 | No |
3640 | 1082 | 1082.0 | 29.18 | 29.2 | What you see may not be what you get: a brief, nontechnical introduction to overfitting in regression-type models. | Michael A Babyak | Psychosom Med | 2004 | 15184705 | Yes |
3641 | 1082 | 1082.0 | 33.7 | 33.7 | Lanthanide luminescence for biomedical analyses and imaging. | Jean-Claude G Bünzli | Chem Rev | 2010 | 20151630 | No |
3642 | 1082 | 1082.0 | 38.2 | 38.2 | Epidemiology of heart failure. | Véronique L Roger | Circ Res | 2013 | 23989710 | No |
3643 | 2163 | 1081.5 | 42.04 | 21.0 | STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. | Hiroki Ishikawa, Glen N Barber | Nature | 2008 | 18724357 | Yes |
3644 | 3244 | 1081.3 | 84.64 | 28.2 | Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. | M K Parmar, V Torri, L Stewart | Stat Med | 1998 | 9921604 | Yes |
3645 | 1081 | 1081.0 | 32.8 | 32.8 | Association of the B-cell alloantigen DRw4 with rheumatoid arthritis. | P Stastny | N Engl J Med | 1978 | 147420 | Yes |
3646 | 1081 | 1081.0 | 20.72 | 20.7 | Radiochemical micro assays for the determination of choline acetyltransferase and acetylcholinesterase activities. | F Fonnum | Biochem J | 1969 | 4982085 | Yes |
3647 | 2162 | 1081.0 | 45.15 | 22.6 | Mitogen-activated protein kinase pathways. | M J Robinson, M H Cobb | Curr Opin Cell Biol | 1997 | 9069255 | No |
3648 | 1081 | 1081.0 | 22.38 | 22.4 | Likelihood ratio tests for detecting positive selection and application to primate lysozyme evolution. | Z Yang | Mol Biol Evol | 1998 | 9580986 | Yes |
3649 | 1081 | 1081.0 | 0.0 | 0.0 | The effect of emotion on cue utilization and the organization of behavior. | J A Easterbrook | Psychol Rev | 1959 | 13658305 | Yes |
3650 | 2162 | 1081.0 | 65.82 | 32.9 | Ischemia and reperfusion--from mechanism to translation. | Holger K Eltzschig, Tobias Eckle | Nat Med | 2011 | 22064429 | No |
3651 | 2161 | 1080.5 | 64.89 | 32.4 | A rapid, sensitive, and versatile assay for protein using Coomassie brilliant blue G250. | J J Sedmak, S E Grossberg | Anal Biochem | 1977 | 68686 | Yes |
3652 | 1080 | 1080.0 | 61.7 | 61.7 | The contribution of the social environment to host resistance: the Fourth Wade Hampton Frost Lecture. | J Cassel | Am J Epidemiol | 1976 | 782233 | No |
3653 | 3240 | 1080.0 | 115.53 | 38.5 | Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. | P S Walsh, D A Metzger, R Higuchi | Biotechniques | 1991 | 1867860 | Yes |
3654 | 2160 | 1080.0 | 63.33 | 31.7 | Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation. | J M Reul, E R de Kloet | Endocrinology | 1985 | 2998738 | Yes |
3655 | 1080 | 1080.0 | 21.41 | 21.4 | Protein denaturation. C. Theoretical models for the mechanism of denaturation. | C Tanford | Adv Protein Chem | 1970 | 4912353 | No |
3656 | 1080 | 1080.0 | 21.41 | 21.4 | Nonlinear structured-illumination microscopy: wide-field fluorescence imaging with theoretically unlimited resolution. | Mats G L Gustafsson | Proc Natl Acad Sci U S A | 2005 | 16141335 | Yes |
3657 | 1080 | 1080.0 | 20.77 | 20.8 | mTOR and cancer: insights into a complex relationship. | David M Sabatini | Nat Rev Cancer | 2006 | 16915295 | No |
3658 | 4316 | 1079.0 | 157.19 | 39.3 | Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. | K F Schulz, I Chalmers, R J Hayes, D G Altman | JAMA | 1995 | 7823387 | Yes |
3659 | 1079 | 1079.0 | 8.27 | 8.3 | The Permeability Of Capillaries In Various Organs As Determined By Use Of The 'Indicator Diffusion' Method. | C Crone | Acta Physiol Scand | 1963 | 14078649 | Yes |
3660 | 1079 | 1079.0 | 27.11 | 27.1 | Fibrinogen and fibrin structure and functions. | M W Mosesson | J Thromb Haemost | 2005 | 16102057 | No |
3661 | 6471 | 1078.5 | 138.9 | 23.2 | Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. | D A Melton, P A Krieg, M R Rebagliati, T Maniatis, K Zinn, M R Green | Nucleic Acids Res | 1984 | 6091052 | Yes |
3662 | 1078 | 1078.0 | 25.4 | 25.4 | Nitric oxide, oxidants, and protein tyrosine nitration. | Rafael Radi | Proc Natl Acad Sci U S A | 2004 | 15020765 | Yes |
3663 | 1078 | 1078.0 | 39.56 | 39.6 | The pathobiology of vascular dementia. | Costantino Iadecola | Neuron | 2013 | 24267647 | No |
3664 | 2155 | 1077.5 | 43.58 | 21.8 | In search of the 'missing self': MHC molecules and NK cell recognition. | H G Ljunggren, K Kärre | Immunol Today | 1990 | 2201309 | No |
3665 | 2155 | 1077.5 | 96.6 | 48.3 | Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics. | J B Mulliken, J Glowacki | Plast Reconstr Surg | 1982 | 7063565 | Yes |
3666 | 2155 | 1077.5 | 46.3 | 23.1 | Finding and evaluating community structure in networks. | M E J Newman, M Girvan | Phys Rev E Stat Nonlin Soft Matter Phys | 2004 | 14995526 | Yes |
3667 | 1077 | 1077.0 | 16.0 | 16.0 | The moulding of senescence by natural selection. | W D Hamilton | J Theor Biol | 1966 | 6015424 | Yes |
3668 | 1077 | 1077.0 | 35.85 | 35.9 | Why we need observational studies to evaluate the effectiveness of health care. | N Black | BMJ | 1996 | 8634569 | Yes |
3669 | 1077 | 1077.0 | 18.8 | 18.8 | Regulatory T cells in autoimmmunity*. | E M Shevach | Annu Rev Immunol | 2000 | 10837065 | No |
3670 | 2154 | 1077.0 | 39.74 | 19.9 | AP-1 as a regulator of cell life and death. | Eitan Shaulian, Michael Karin | Nat Cell Biol | 2002 | 11988758 | No |
3671 | 3228 | 1076.0 | 127.23 | 42.4 | Concurrent and predictive validity of a self-reported measure of medication adherence. | D E Morisky, L W Green, D M Levine | Med Care | 1986 | 3945130 | Yes |
3672 | 1076 | 1076.0 | 28.94 | 28.9 | Statistical quality control and routine data processing for radioimmunoassays and immunoradiometric assays. | D Rodbard | Clin Chem | 1974 | 4370388 | No |
3673 | 1076 | 1076.0 | 37.84 | 37.8 | Coronary physiology. | E O Feigl | Physiol Rev | 1983 | 6296890 | No |
3674 | 1076 | 1076.0 | 36.02 | 36.0 | Lipid peroxidation and antioxidants as biomarkers of tissue damage. | J M Gutteridge | Clin Chem | 1995 | 7497639 | No |
3675 | 2152 | 1076.0 | 60.95 | 30.5 | Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for Gram-negative bacteria. | Ivan Sondi, Branka Salopek-Sondi | J Colloid Interface Sci | 2004 | 15158396 | Yes |
3676 | 1076 | 1076.0 | 25.77 | 25.8 | ImageJ for microscopy. | Tony J Collins | Biotechniques | 2007 | 17936939 | No |
3677 | 2152 | 1076.0 | 246.53 | 123.3 | Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019. | David J Newman, Gordon M Cragg | J Nat Prod | 2020 | 32162523 | No |
3678 | 1075 | 1075.0 | 24.81 | 24.8 | Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology. | E M Tan | Adv Immunol | 1989 | 2646863 | No |
3679 | 3225 | 1075.0 | 152.66 | 50.9 | Development of an upper extremity outcome measure: the DASH (disabilities of the arm, shoulder and hand) [corrected]. The Upper Extremity Collaborative Group (UECG) | P L Hudak, P C Amadio, C Bombardier | Am J Ind Med | 1996 | 8773720 | Yes |
3680 | 1075 | 1075.0 | 18.26 | 18.3 | Molecular mechanisms of axon guidance. | Barry J Dickson | Science | 2002 | 12471249 | No |
3681 | 1075 | 1075.0 | 30.05 | 30.1 | The locus coeruleus and noradrenergic modulation of cognition. | Susan J Sara | Nat Rev Neurosci | 2009 | 19190638 | No |
3682 | 2148 | 1074.0 | 82.77 | 41.4 | Hearing lips and seeing voices. | H McGurk, J MacDonald | Nature | 1976 | 1012311 | Yes |
3683 | 2148 | 1074.0 | 43.07 | 21.5 | A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli. | C S Hoffman, F Winston | Gene | 1987 | 3319781 | Yes |
3684 | 1074 | 1074.0 | 27.39 | 27.4 | Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system. | J P Tam | Proc Natl Acad Sci U S A | 1988 | 3399498 | Yes |
3685 | 1074 | 1074.0 | 28.32 | 28.3 | Microtubule formation in vitro in solutions containing low calcium concentrations. | R C Weisenberg | Science | 1972 | 4626639 | Yes |
3686 | 1074 | 1074.0 | 33.36 | 33.4 | Food reward: brain substrates of wanting and liking. | K C Berridge | Neurosci Biobehav Rev | 1996 | 8622814 | No |
3687 | 1074 | 1074.0 | 23.35 | 23.4 | ECM and cell surface proteolysis: regulating cellular ecology. | Z Werb | Cell | 1997 | 9390552 | No |
3688 | 1074 | 1074.0 | 28.42 | 28.4 | Invited review: Aging and sarcopenia. | Timothy J Doherty | J Appl Physiol (1985) | 2003 | 12970377 | No |
3689 | 3221 | 1073.7 | 63.06 | 21.0 | Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. | Paola Scaffidi, Tom Misteli, Marco E Bianchi | Nature | 2002 | 12110890 | Yes |
3690 | 6442 | 1073.7 | 174.38 | 29.1 | Cancer statistics, 2007. | Ahmedin Jemal, Rebecca Siegel, Elizabeth Ward, Taylor Murray, Jiaquan Xu, Michael J Thun | CA Cancer J Clin | 2007 | 17237035 | Yes |
3691 | 2147 | 1073.5 | 60.42 | 30.2 | Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. | Amit Etkin, Tor D Wager | Am J Psychiatry | 2007 | 17898336 | Yes |
3692 | 3220 | 1073.3 | 75.5 | 25.2 | Arabidopsis mesophyll protoplasts: a versatile cell system for transient gene expression analysis. | Sang-Dong Yoo, Young-Hee Cho, Jen Sheen | Nat Protoc | 2007 | 17585298 | Yes |
3693 | 1073 | 1073.0 | 41.67 | 41.7 | Functional connections between cells as revealed by dye-coupling with a highly fluorescent naphthalimide tracer. | W W Stewart | Cell | 1978 | 688392 | Yes |
3694 | 1073 | 1073.0 | 40.14 | 40.1 | Beyond curriculum reform: confronting medicine's hidden curriculum. | F W Hafferty | Acad Med | 1998 | 9580717 | Yes |
3695 | 2146 | 1073.0 | 83.24 | 41.6 | Chronic catheterization of the spinal subarachnoid space. | T L Yaksh, T A Rudy | Physiol Behav | 1976 | 14677603 | Yes |
3696 | 1073 | 1073.0 | 29.55 | 29.6 | Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review. | John W Newcomer | CNS Drugs | 2005 | 15998156 | No |
3697 | 1073 | 1073.0 | 27.37 | 27.4 | Redefining oxidative stress. | Dean P Jones | Antioxid Redox Signal | 2006 | 16987039 | No |
3698 | 1073 | 1073.0 | 24.02 | 24.0 | Liver regeneration. | George K Michalopoulos | J Cell Physiol | 2007 | 17559071 | No |
3699 | 1073 | 1073.0 | 32.77 | 32.8 | On the mechanisms of biocompatibility. | David F Williams | Biomaterials | 2008 | 18440630 | No |
3700 | 1073 | 1073.0 | 29.61 | 29.6 | Principles of c-di-GMP signalling in bacteria. | Regine Hengge | Nat Rev Microbiol | 2009 | 19287449 | No |
3701 | 2145 | 1072.5 | 83.49 | 41.7 | Glutathione reductase. | I Carlberg, B Mannervik | Methods Enzymol | 1985 | 3003504 | Yes |
3702 | 1072 | 1072.0 | 18.1 | 18.1 | Evolution and tinkering. | F Jacob | Science | 1977 | 860134 | Yes |
3703 | 1072 | 1072.0 | 28.92 | 28.9 | A perspective on judgment and choice: mapping bounded rationality. | Daniel Kahneman | Am Psychol | 2003 | 14584987 | No |
3704 | 2144 | 1072.0 | 54.31 | 27.2 | Antibacterial resistance worldwide: causes, challenges and responses. | Stuart B Levy, Bonnie Marshall | Nat Med | 2004 | 15577930 | No |
3705 | 4287 | 1071.8 | 240.94 | 60.2 | The Cambridge Structural Database. | Colin R Groom, Ian J Bruno, Matthew P Lightfoot, Suzanna C Ward | Acta Crystallogr B Struct Sci Cryst Eng Mater | 2016 | 27048719 | Yes |
3706 | 1071 | 1071.0 | 52.78 | 52.8 | The sociological study of stress. | L I Pearlin | J Health Soc Behav | 1989 | 2674272 | No |
3707 | 1071 | 1071.0 | 30.99 | 31.0 | Microbial heavy-metal resistance. | D H Nies | Appl Microbiol Biotechnol | 1999 | 10422221 | No |
3708 | 1071 | 1071.0 | 29.12 | 29.1 | Ion suppression in mass spectrometry. | Thomas M Annesley | Clin Chem | 2003 | 12816898 | No |
3709 | 1071 | 1071.0 | 55.21 | 55.2 | Systematic text condensation: a strategy for qualitative analysis. | Kirsti Malterud | Scand J Public Health | 2012 | 23221918 | Yes |
3710 | 11776 | 1070.5 | 334.0 | 30.4 | International physical activity questionnaire: 12-country reliability and validity. | Cora L Craig, Alison L Marshall, Michael Sjöström, Adrian E Bauman, Michael L Booth, Barbara E Ainsworth, Michael Pratt, Ulf Ekelund, Agneta Yngve, James F Sallis, Pekka Oja | Med Sci Sports Exerc | 2003 | 12900694 | Yes |
3711 | 2141 | 1070.5 | 75.64 | 37.8 | Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier. | Hirenkumar K Makadia, Steven J Siegel | Polymers (Basel) | 2011 | 22577513 | Yes |
3712 | 10703 | 1070.3 | 352.82 | 35.3 | The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. | N K Aaronson, S Ahmedzai, B Bergman, M Bullinger, A Cull, N J Duez, A Filiberti, H Flechtner, S B Fleishman, J C de Haes | J Natl Cancer Inst | 1993 | 8433390 | Yes |
3713 | 1070 | 1070.0 | 26.48 | 26.5 | The glycemic index: physiological mechanisms relating to obesity, diabetes, and cardiovascular disease. | David S Ludwig | JAMA | 2002 | 11988062 | No |
3714 | 1070 | 1070.0 | 28.21 | 28.2 | Bile acids: regulation of synthesis. | John Y L Chiang | J Lipid Res | 2009 | 19346330 | No |
3715 | 1070 | 1070.0 | 28.51 | 28.5 | An introduction to data reduction: space-group determination, scaling and intensity statistics. | Philip R Evans | Acta Crystallogr D Biol Crystallogr | 2011 | 21460446 | Yes |
3716 | 1070 | 1070.0 | 31.26 | 31.3 | Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy. | Gregg L Semenza | Trends Pharmacol Sci | 2012 | 22398146 | No |
3717 | 2138 | 1069.0 | 71.45 | 35.7 | The pathogenesis of atherosclerosis (first of two parts). | R Ross, J A Glomset | N Engl J Med | 1976 | 819830 | No |
3718 | 1069 | 1069.0 | 27.08 | 27.1 | Axonal growth-associated proteins. | J H Skene | Annu Rev Neurosci | 1989 | 2648946 | No |
3719 | 1069 | 1069.0 | 26.33 | 26.3 | Anti-inflammatory actions of glucocorticoids: molecular mechanisms. | P J Barnes | Clin Sci (Lond) | 1998 | 9854452 | No |
3720 | 1069 | 1069.0 | 26.24 | 26.2 | Biological effects of resveratrol. | L Frémont | Life Sci | 2000 | 10680575 | No |
3721 | 2137 | 1068.5 | 90.77 | 45.4 | Severe psoriasis--oral therapy with a new retinoid. | T Fredriksson, U Pettersson | Dermatologica | 1978 | 357213 | Yes |
3722 | 2136 | 1068.0 | 59.95 | 30.0 | Binding of soluble form of fibroblast surface protein, fibronectin, to collagen. | E Engvall, E Ruoslahti | Int J Cancer | 1977 | 903179 | Yes |
3723 | 1068 | 1068.0 | 29.7 | 29.7 | Mitochondrial genetics: a paradigm for aging and degenerative diseases? | D C Wallace | Science | 1992 | 1533953 | Yes |
3724 | 1068 | 1068.0 | 38.81 | 38.8 | Attention, similarity, and the identification-categorization relationship. | R M Nosofsky | J Exp Psychol Gen | 1986 | 2937873 | Yes |
3725 | 1068 | 1068.0 | 25.68 | 25.7 | The ultrastructural basis of capillary permeability studied with peroxidase as a tracer. | M J Karnovsky | J Cell Biol | 1967 | 6061717 | Yes |
3726 | 1068 | 1068.0 | 30.65 | 30.6 | Muscarinic receptors--characterization, coupling and function. | M P Caulfield | Pharmacol Ther | 1993 | 7504306 | No |
3727 | 2136 | 1068.0 | 37.47 | 18.7 | Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. | W Gu, R G Roeder | Cell | 1997 | 9288740 | Yes |
3728 | 1068 | 1068.0 | 28.02 | 28.0 | Philosophical conceptions of the self: implications for cognitive science. | I Gallagher | Trends Cogn Sci | 2000 | 10637618 | Yes |
3729 | 1068 | 1068.0 | 24.67 | 24.7 | Structure and signalling in the IL-17 receptor family. | Sarah L Gaffen | Nat Rev Immunol | 2009 | 19575028 | No |
3730 | 4271 | 1067.8 | 109.47 | 27.4 | Real time quantitative PCR. | C A Heid, J Stevens, K J Livak, P M Williams | Genome Res | 1996 | 8908518 | Yes |
3731 | 3202 | 1067.3 | 67.55 | 22.5 | 5-fluorouracil: mechanisms of action and clinical strategies. | Daniel B Longley, D Paul Harkin, Patrick G Johnston | Nat Rev Cancer | 2003 | 12724731 | No |
3732 | 4269 | 1067.2 | 110.09 | 27.5 | A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. | I Vermes, C Haanen, H Steffens-Nakken, C Reutelingsperger | J Immunol Methods | 1995 | 7622868 | Yes |
3733 | 1067 | 1067.0 | 30.24 | 30.2 | Autoantibodies to nuclear antigens (ANA): their immunobiology and medicine. | E M Tan | Adv Immunol | 1982 | 6182766 | No |
3734 | 1067 | 1067.0 | 24.17 | 24.2 | The neurobiology of consolidations, or, how stable is the engram? | Yadin Dudai | Annu Rev Psychol | 2004 | 14744210 | No |
3735 | 2133 | 1066.5 | 62.8 | 31.4 | Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. | C N Hales, D J Barker | Diabetologia | 1992 | 1644236 | No |
3736 | 2133 | 1066.5 | 78.97 | 39.5 | Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. | Claudio Franceschi, Judith Campisi | J Gerontol A Biol Sci Med Sci | 2014 | 24833586 | No |
3737 | 1066 | 1066.0 | 50.23 | 50.2 | Clinical experience with impedance audiometry. | J Jerger | Arch Otolaryngol | 1970 | 5455571 | Yes |
3738 | 2132 | 1066.0 | 52.17 | 26.1 | Sulforhodamine B colorimetric assay for cytotoxicity screening. | Vanicha Vichai, Kanyawim Kirtikara | Nat Protoc | 2006 | 17406391 | Yes |
3739 | 1066 | 1066.0 | 28.51 | 28.5 | Neuronal gamma-band synchronization as a fundamental process in cortical computation. | Pascal Fries | Annu Rev Neurosci | 2009 | 19400723 | No |
3740 | 3197 | 1065.7 | 142.63 | 47.5 | Surface markers on human T and B lymphocytes. I. A large population of lymphocytes forming nonimmune rosettes with sheep red blood cells. | M Jondal, G Holm, H Wigzell | J Exp Med | 1972 | 4114496 | Yes |
3741 | 3197 | 1065.7 | 87.01 | 29.0 | Improved vectors and genome-wide libraries for CRISPR screening. | Neville E Sanjana, Ophir Shalem, Feng Zhang | Nat Methods | 2014 | 25075903 | Yes |
3742 | 4261 | 1065.2 | 217.36 | 54.3 | National Institute of Mental Health Diagnostic Interview Schedule. Its history, characteristics, and validity. | L N Robins, J E Helzer, J Croughan, K S Ratcliff | Arch Gen Psychiatry | 1981 | 6260053 | Yes |
3743 | 6391 | 1065.2 | 177.19 | 29.5 | Mild cognitive impairment: clinical characterization and outcome. | R C Petersen, G E Smith, S C Waring, R J Ivnik, E G Tangalos, E Kokmen | Arch Neurol | 1999 | 10190820 | Yes |
3744 | 2129 | 1064.5 | 53.29 | 26.6 | The regulation and function of c-fos and other immediate early genes in the nervous system. | M Sheng, M E Greenberg | Neuron | 1990 | 1969743 | No |
3745 | 2129 | 1064.5 | 42.08 | 21.0 | Calcium-dependent bacteriophage DNA infection. | M Mandel, A Higa | J Mol Biol | 1970 | 4922220 | Yes |
3746 | 2129 | 1064.5 | 116.61 | 58.3 | Sexually transmitted diseases treatment guidelines, 2015. | Kimberly A Workowski, Gail A Bolan | MMWR Recomm Rep | 2015 | 26042815 | No |
3747 | 4257 | 1064.2 | 101.34 | 25.3 | The epidemiology of sepsis in the United States from 1979 through 2000. | Greg S Martin, David M Mannino, Stephanie Eaton, Marc Moss | N Engl J Med | 2003 | 12700374 | Yes |
3748 | 1064 | 1064.0 | 21.76 | 21.8 | The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells. | D Metcalf | Nature | 1989 | 2469962 | No |
3749 | 1064 | 1064.0 | 31.1 | 31.1 | Why people use health services. | I M Rosenstock | Milbank Mem Fund Q | 1966 | 5967464 | Yes |
3750 | 1064 | 1064.0 | 28.65 | 28.6 | Interval estimation for the difference between independent proportions: comparison of eleven methods. | R G Newcombe | Stat Med | 1998 | 9595617 | Yes |
3751 | 1064 | 1064.0 | 22.09 | 22.1 | Oxidant signals and oxidative stress. | Toren Finkel | Curr Opin Cell Biol | 2003 | 12648682 | No |
3752 | 1064 | 1064.0 | 25.85 | 25.9 | Looking into the functional architecture of the brain with diffusion MRI. | Denis Le Bihan | Nat Rev Neurosci | 2003 | 12778119 | No |
3753 | 1064 | 1064.0 | 32.61 | 32.6 | Social cognition and the brain: a meta-analysis. | Frank Van Overwalle | Hum Brain Mapp | 2009 | 18381770 | Yes |
3754 | 1064 | 1064.0 | 76.48 | 76.5 | Epidemiology of Prostate Cancer. | Prashanth Rawla | World J Oncol | 2019 | 31068988 | No |
3755 | 2127 | 1063.5 | 54.03 | 27.0 | Anemia of chronic disease. | Guenter Weiss, Lawrence T Goodnough | N Engl J Med | 2005 | 15758012 | No |
3756 | 5317 | 1063.4 | 193.98 | 38.8 | A new clinical scale for the staging of dementia. | C P Hughes, L Berg, W L Danziger, L A Coben, R L Martin | Br J Psychiatry | 1982 | 7104545 | Yes |
3757 | 1063 | 1063.0 | 35.31 | 35.3 | A colorimetric method for estimating serum triglycerides. | M J Fletcher | Clin Chim Acta | 1968 | 5696963 | Yes |
3758 | 1063 | 1063.0 | 29.82 | 29.8 | Junctional intercellular communication: the cell-to-cell membrane channel. | W R Loewenstein | Physiol Rev | 1981 | 6270711 | No |
3759 | 1063 | 1063.0 | 29.13 | 29.1 | Synchronization of cortical activity and its putative role in information processing and learning. | W Singer | Annu Rev Physiol | 1993 | 8466179 | No |
3760 | 1063 | 1063.0 | 30.46 | 30.5 | Pathogenetic mechanisms of septic shock. | J E Parrillo | N Engl J Med | 1993 | 8479467 | No |
3761 | 1063 | 1063.0 | 28.46 | 28.5 | Inhibition of return. | R M Klein | Trends Cogn Sci | 2000 | 10740278 | Yes |
3762 | 1063 | 1063.0 | 30.02 | 30.0 | The mechanisms of alloxan- and streptozotocin-induced diabetes. | S Lenzen | Diabetologia | 2008 | 18087688 | No |
3763 | 1063 | 1063.0 | 142.24 | 142.2 | COVID-19 Vaccine Hesitancy Worldwide: A Concise Systematic Review of Vaccine Acceptance Rates. | Malik Sallam | Vaccines (Basel) | 2021 | 33669441 | No |
3764 | 2125 | 1062.5 | 56.12 | 28.1 | The evolution of cooperation. | R Axelrod, W D Hamilton | Science | 1981 | 7466396 | Yes |
3765 | 2125 | 1062.5 | 72.72 | 36.4 | Photoacoustic tomography: in vivo imaging from organelles to organs. | Lihong V Wang, Song Hu | Science | 2012 | 22442475 | No |
3766 | 1062 | 1062.0 | 25.5 | 25.5 | The granulocyte-macrophage colony-stimulating factors. | D Metcalf | Science | 1985 | 2990035 | No |
3767 | 2124 | 1062.0 | 80.57 | 40.3 | Societal and individual determinants of medical care utilization in the United States. | R Andersen, J F Newman | Milbank Mem Fund Q Health Soc | 1973 | 4198894 | Yes |
3768 | 1062 | 1062.0 | 32.7 | 32.7 | Prevention of drug access to bacterial targets: permeability barriers and active efflux. | H Nikaido | Science | 1994 | 8153625 | No |
3769 | 6372 | 1062.0 | 161.81 | 27.0 | Ghrelin is a growth-hormone-releasing acylated peptide from stomach. | M Kojima, H Hosoda, Y Date, M Nakazato, H Matsuo, K Kangawa | Nature | 1999 | 10604470 | Yes |
3770 | 1062 | 1062.0 | 22.84 | 22.8 | Ligand-targeted therapeutics in anticancer therapy. | Theresa M Allen | Nat Rev Cancer | 2002 | 12360278 | No |
3771 | 1062 | 1062.0 | 34.04 | 34.0 | Isolation By Distance In Equilibrium And Non-Equilibrium Populations. | Montgomery Slatkin | Evolution | 1993 | 28568097 | Yes |
3772 | 5308 | 1061.6 | 144.2 | 28.8 | Biodiversity hotspots for conservation priorities. | N Myers, R A Mittermeier, C G Mittermeier, G A da Fonseca, J Kent | Nature | 2000 | 10706275 | Yes |
3773 | 2123 | 1061.5 | 87.49 | 43.7 | Communication by Extracellular Vesicles: Where We Are and Where We Need to Go. | Mercedes Tkach, Clotilde Théry | Cell | 2016 | 26967288 | No |
3774 | 3183 | 1061.0 | 80.97 | 27.0 | Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions. | M Piotto, V Saudek, V Sklenár | J Biomol NMR | 1992 | 1490109 | Yes |
3775 | 1061 | 1061.0 | 39.39 | 39.4 | Infection by verocytotoxin-producing Escherichia coli. | M A Karmali | Clin Microbiol Rev | 1989 | 2644022 | No |
3776 | 1061 | 1061.0 | 31.62 | 31.6 | Epidemiology of cancer of the colon and rectum. | D P Burkitt | Cancer | 1971 | 5165022 | Yes |
3777 | 1061 | 1061.0 | 18.89 | 18.9 | Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. | W Kolch | Biochem J | 2000 | 11023813 | No |
3778 | 1061 | 1061.0 | 25.47 | 25.5 | Context, ambiguity, and unlearning: sources of relapse after behavioral extinction. | Mark E Bouton | Biol Psychiatry | 2002 | 12437938 | No |
3779 | 1061 | 1061.0 | 27.87 | 27.9 | Physiology and immunology of the cholinergic antiinflammatory pathway. | Kevin J Tracey | J Clin Invest | 2007 | 17273548 | No |
3780 | 1061 | 1061.0 | 0.0 | 0.0 | A Serological Differentiation Of Human And Other Groups Of Hemolytic Streptococci. | R C Lancefield | J Exp Med | 1933 | 19870148 | Yes |
3781 | 1061 | 1061.0 | 23.03 | 23.0 | Serine/threonine phosphatases: mechanism through structure. | Yigong Shi | Cell | 2009 | 19879837 | No |
3782 | 2121 | 1060.5 | 0.0 | 0.0 | Histochemistry of hepatic phosphatases of a physiologic pH; with special reference to the demonstration of bile canaliculi. | M Wachstein, E Meisel | Am J Clin Pathol | 1957 | 13410831 | Yes |
3783 | 2121 | 1060.5 | 0.0 | 0.0 | Use of glucose oxidase, peroxidase, and O-dianisidine in determination of blood and urinary glucose. | A S Huggett, D A Nixon | Lancet | 1957 | 13464070 | Yes |
3784 | 2121 | 1060.5 | 258.23 | 129.1 | Mental Health and the Covid-19 Pandemic. | Betty Pfefferbaum, Carol S North | N Engl J Med | 2020 | 32283003 | Yes |
3785 | 2120 | 1060.0 | 79.46 | 39.7 | A psychomotor stimulant theory of addiction. | R A Wise, M A Bozarth | Psychol Rev | 1987 | 3317472 | No |
3786 | 2120 | 1060.0 | 32.87 | 16.4 | The growth of mouse bone marrow cells in vitro. | T R Bradley, D Metcalf | Aust J Exp Biol Med Sci | 1966 | 4164182 | Yes |
3787 | 1060 | 1060.0 | 74.18 | 74.2 | Root canal anatomy of the human permanent teeth. | F J Vertucci | Oral Surg Oral Med Oral Pathol | 1984 | 6595621 | Yes |
3788 | 1060 | 1060.0 | 34.74 | 34.7 | Perceptual load as a necessary condition for selective attention. | N Lavie | J Exp Psychol Hum Percept Perform | 1995 | 7790827 | Yes |
3789 | 1060 | 1060.0 | 41.58 | 41.6 | Gait changes in older adults: predictors of falls or indicators of fear. | B E Maki | J Am Geriatr Soc | 1997 | 9063277 | Yes |
3790 | 1060 | 1060.0 | 0.0 | 0.0 | On the Absorption of Fluids from the Connective Tissue Spaces. | E H Starling | J Physiol | 1896 | 16992325 | Yes |
3791 | 1060 | 1060.0 | 36.97 | 37.0 | Stochastic thermodynamics, fluctuation theorems and molecular machines. | Udo Seifert | Rep Prog Phys | 2012 | 23168354 | No |
3792 | 2119 | 1059.5 | 61.8 | 30.9 | The biochemistry of P-glycoprotein-mediated multidrug resistance. | J A Endicott, V Ling | Annu Rev Biochem | 1989 | 2570548 | No |
3793 | 2119 | 1059.5 | 54.04 | 27.0 | Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. | M S Brown, J L Goldstein | Annu Rev Biochem | 1983 | 6311077 | No |
3794 | 2119 | 1059.5 | 48.01 | 24.0 | The significance of digital gene expression profiles. | S Audic, J M Claverie | Genome Res | 1997 | 9331369 | Yes |
3795 | 2119 | 1059.5 | 40.11 | 20.1 | Wnt signaling: a common theme in animal development. | K M Cadigan, R Nusse | Genes Dev | 1997 | 9407023 | No |
3796 | 2119 | 1059.5 | 0.0 | 0.0 | A microcolorimetric method for the determination of inorganic phosphorus. | H H Taussky, E Shorr | J Biol Chem | 1953 | 13061491 | Yes |
3797 | 3178 | 1059.3 | 95.67 | 31.9 | HMMER web server: interactive sequence similarity searching. | Robert D Finn, Jody Clements, Sean R Eddy | Nucleic Acids Res | 2011 | 21593126 | Yes |
3798 | 1059 | 1059.0 | 43.37 | 43.4 | Movement, posture and equilibrium: interaction and coordination. | J Massion | Prog Neurobiol | 1992 | 1736324 | No |
3799 | 1059 | 1059.0 | 24.46 | 24.5 | Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note. | S H Kaufmann | Cancer Res | 1989 | 2790800 | Yes |
3800 | 1059 | 1059.0 | 29.85 | 29.9 | Determination of total protein. | G L Peterson | Methods Enzymol | 1983 | 6855607 | Yes |
3801 | 2118 | 1059.0 | 43.25 | 21.6 | Modified reagents for determination of urea and ammonia. | A L Chaney, E P Marbach | Clin Chem | 1962 | 13878063 | Yes |
3802 | 1059 | 1059.0 | 27.41 | 27.4 | Targeting cancer metabolism: a therapeutic window opens. | Matthew G Vander Heiden | Nat Rev Drug Discov | 2011 | 21878982 | No |
3803 | 3176 | 1058.7 | 76.12 | 25.4 | Nitric oxide and macrophage function. | J MacMicking, Q W Xie, C Nathan | Annu Rev Immunol | 1997 | 9143691 | No |
3804 | 2117 | 1058.5 | 108.82 | 54.4 | The Neck Disability Index: a study of reliability and validity. | H Vernon, S Mior | J Manipulative Physiol Ther | 1991 | 1834753 | Yes |
3805 | 2117 | 1058.5 | 47.94 | 24.0 | Effect of pegylation on pharmaceuticals. | J Milton Harris, Robert B Chess | Nat Rev Drug Discov | 2003 | 12612647 | No |
3806 | 2116 | 1058.0 | 45.28 | 22.6 | The immunoglobulin superfamily--domains for cell surface recognition. | A F Williams, A N Barclay | Annu Rev Immunol | 1988 | 3289571 | No |
3807 | 4232 | 1058.0 | 105.87 | 26.5 | An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. | Joseph A Maldjian, Paul J Laurienti, Robert A Kraft, Jonathan H Burdette | Neuroimage | 2003 | 12880848 | Yes |
3808 | 1058 | 1058.0 | 26.74 | 26.7 | The potential environmental impact of engineered nanomaterials. | Vicki L Colvin | Nat Biotechnol | 2003 | 14520401 | Yes |
3809 | 1058 | 1058.0 | 29.79 | 29.8 | Micellar nanocarriers: pharmaceutical perspectives. | V P Torchilin | Pharm Res | 2007 | 17109211 | No |
3810 | 2115 | 1057.5 | 68.05 | 34.0 | Population growth makes waves in the distribution of pairwise genetic differences. | A R Rogers, H Harpending | Mol Biol Evol | 1992 | 1316531 | Yes |
3811 | 1057 | 1057.0 | 0.0 | 0.0 | Neural basis of the spontaneous optokinetic response produced by visual inversion. | R W Sperry | J Comp Physiol Psychol | 1950 | 14794830 | Yes |
3812 | 1057 | 1057.0 | 30.45 | 30.4 | A comprehensive definition for metabolic syndrome. | Paul L Huang | Dis Model Mech | 2009 | 19407331 | No |
3813 | 2113 | 1056.5 | 82.13 | 41.1 | Comparative aspects of the brain growth spurt. | J Dobbing, J Sands | Early Hum Dev | 1979 | 118862 | Yes |
3814 | 2113 | 1056.5 | 68.82 | 34.4 | Polymyositis and dermatomyositis (second of two parts). | A Bohan, J B Peter | N Engl J Med | 1975 | 1089199 | No |
3815 | 1056 | 1056.0 | 28.45 | 28.4 | T-cell growth factor. | K A Smith | Immunol Rev | 1980 | 7000676 | No |
3816 | 2112 | 1056.0 | 42.25 | 21.1 | IAP family proteins--suppressors of apoptosis. | Q L Deveraux, J C Reed | Genes Dev | 1999 | 9990849 | No |
3817 | 1056 | 1056.0 | 26.86 | 26.9 | From Microporous to Mesoporous Molecular Sieve Materials and Their Use in Catalysis. | Avelino Corma | Chem Rev | 1997 | 11848903 | Yes |
3818 | 1056 | 1056.0 | 45.56 | 45.6 | Bisphenol A and human health: a review of the literature. | Johanna R Rochester | Reprod Toxicol | 2013 | 23994667 | No |
3819 | 2111 | 1055.5 | 43.2 | 21.6 | The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000. | A Bairoch, R Apweiler | Nucleic Acids Res | 2000 | 10592178 | Yes |
3820 | 1055 | 1055.0 | 24.44 | 24.4 | Biochemistry and genetics of von Willebrand factor. | J E Sadler | Annu Rev Biochem | 1998 | 9759493 | No |
3821 | 1055 | 1055.0 | 28.31 | 28.3 | Optogenetics. | Karl Deisseroth | Nat Methods | 2011 | 21191368 | Yes |
3822 | 1055 | 1055.0 | 31.64 | 31.6 | Phosphoinositides: tiny lipids with giant impact on cell regulation. | Tamas Balla | Physiol Rev | 2013 | 23899561 | No |
3823 | 2109 | 1054.5 | 54.03 | 27.0 | Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis. | D C Schwartz, C R Cantor | Cell | 1984 | 6373014 | Yes |
3824 | 1054 | 1054.0 | 26.16 | 26.2 | Skeletal complications of malignancy. | R E Coleman | Cancer | 1997 | 9362426 | No |
3825 | 2107 | 1053.5 | 100.77 | 50.4 | Problems and proposals for recording gingivitis and plaque. | J Ainamo, I Bay | Int Dent J | 1975 | 1058834 | Yes |
3826 | 2107 | 1053.5 | 77.85 | 38.9 | Fingerprinting genomes using PCR with arbitrary primers. | J Welsh, M McClelland | Nucleic Acids Res | 1990 | 2259619 | Yes |
3827 | 3160 | 1053.3 | 66.26 | 22.1 | TGF-beta signalling from cell membrane to nucleus through SMAD proteins. | C H Heldin, K Miyazono, P ten Dijke | Nature | 1997 | 9393997 | No |
3828 | 1053 | 1053.0 | 39.78 | 39.8 | The ovariectomized rat model of postmenopausal bone loss. | D N Kalu | Bone Miner | 1991 | 1773131 | No |
3829 | 1053 | 1053.0 | 29.63 | 29.6 | Hepatitis B virus. The major etiology of hepatocellular carcinoma. | R P Beasley | Cancer | 1988 | 2834034 | No |
Download as CSV