No. | Citations | ECcit | RCR | ECRCR | Title | Authors | Journal | Year | PMID | Article(?) |
---|---|---|---|---|---|---|---|---|---|---|
1 | 224539 | 224539.0 | 5451.14 | 5451.1 | Cleavage of structural proteins during the assembly of the head of bacteriophage T4. | U K Laemmli | Nature | 1970 | 5432063 | Yes |
2 | 171828 | 171828.0 | 6755.3 | 6755.3 | A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. | M M Bradford | Anal Biochem | 1976 | 942051 | Yes |
3 | 285272 | 71318.0 | 0.0 | 0.0 | Protein measurement with the Folin phenol reagent. | O H Lowry, N J Rosebrough, A L Farr, R J Randall | J Biol Chem | 1951 | 14907713 | Yes |
4 | 119444 | 59722.0 | 2963.17 | 1481.6 | Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. | K J Livak, T D Schmittgen | Methods | 2001 | 11846609 | Yes |
5 | 45133 | 45133.0 | 1392.54 | 1392.5 | A short history of SHELX. | George M Sheldrick | Acta Crystallogr A | 2008 | 18156677 | Yes |
6 | 36553 | 36553.0 | 1176.93 | 1176.9 | Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. | T Mosmann | J Immunol Methods | 1983 | 6606682 | Yes |
7 | 64345 | 32172.5 | 1931.6 | 965.8 | Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. | P Chomczynski, N Sacchi | Anal Biochem | 1987 | 2440339 | Yes |
8 | 30258 | 30258.0 | 821.37 | 821.4 | Detection of specific sequences among DNA fragments separated by gel electrophoresis. | E M Southern | J Mol Biol | 1975 | 1195397 | Yes |
9 | 27691 | 27691.0 | 900.98 | 901.0 | The assessment and analysis of handedness: the Edinburgh inventory. | R C Oldfield | Neuropsychologia | 1971 | 5146491 | Yes |
10 | 27592 | 27592.0 | 609.44 | 609.4 | MicroRNAs: genomics, biogenesis, mechanism, and function. | David P Bartel | Cell | 2004 | 14744438 | No |
11 | 26226 | 26226.0 | 620.81 | 620.8 | MUSCLE: multiple sequence alignment with high accuracy and high throughput. | Robert C Edgar | Nucleic Acids Res | 2004 | 15034147 | Yes |
12 | 25735 | 25735.0 | 669.57 | 669.6 | A rating scale for depression. | M Hamilton | J Neurol Neurosurg Psychiatry | 1960 | 14399272 | Yes |
13 | 24313 | 24313.0 | 557.49 | 557.5 | A new mathematical model for relative quantification in real-time RT-PCR. | M W Pfaffl | Nucleic Acids Res | 2001 | 11328886 | Yes |
14 | 24249 | 24249.0 | 751.46 | 751.5 | Confidence Limits On Phylogenies: An Approach Using The Bootstrap. | Joseph Felsenstein | Evolution | 1985 | 28561359 | Yes |
15 | 65928 | 21976.0 | 1647.7 | 549.2 | DNA sequencing with chain-terminating inhibitors. | F Sanger, S Nicklen, A R Coulson | Proc Natl Acad Sci U S A | 1977 | 271968 | Yes |
16 | 65660 | 21886.7 | 2499.48 | 833.2 | "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. | M F Folstein, S E Folstein, P R McHugh | J Psychiatr Res | 1975 | 1202204 | Yes |
17 | 41595 | 20797.5 | 1309.5 | 654.8 | Hallmarks of cancer: the next generation. | Douglas Hanahan, Robert A Weinberg | Cell | 2011 | 21376230 | No |
18 | 20643 | 20643.0 | 711.67 | 711.7 | Density-functional exchange-energy approximation with correct asymptotic behavior. | A D Becke | Phys Rev A Gen Phys | 1988 | 9900728 | Yes |
19 | 20251 | 20251.0 | 147.15 | 147.2 | The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. | E S Reynolds | J Cell Biol | 1963 | 13986422 | Yes |
20 | 39524 | 19762.0 | 1219.34 | 609.7 | The neighbor-joining method: a new method for reconstructing phylogenetic trees. | N Saitou, M Nei | Mol Biol Evol | 1987 | 3447015 | Yes |
21 | 19437 | 19437.0 | 0.0 | 0.0 | Tissue sulfhydryl groups. | G L Ellman | Arch Biochem Biophys | 1959 | 13650640 | Yes |
22 | 35918 | 17959.0 | 1699.3 | 849.6 | Statistical methods for assessing agreement between two methods of clinical measurement. | J M Bland, D G Altman | Lancet | 1986 | 2868172 | Yes |
23 | 17886 | 17886.0 | 501.36 | 501.4 | Projector augmented-wave method. | P E Blöchl | Phys Rev B Condens Matter | 1994 | 9976227 | Yes |
24 | 53522 | 17840.7 | 1974.32 | 658.1 | Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. | H Towbin, T Staehelin, J Gordon | Proc Natl Acad Sci U S A | 1979 | 388439 | Yes |
25 | 34855 | 17427.5 | 1459.21 | 729.6 | The measurement of observer agreement for categorical data. | J R Landis, G G Koch | Biometrics | 1977 | 843571 | Yes |
26 | 17012 | 17012.0 | 622.72 | 622.7 | A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences. | M Kimura | J Mol Evol | 1980 | 7463489 | Yes |
27 | 16890 | 16890.0 | 424.33 | 424.3 | Atherosclerosis--an inflammatory disease. | R Ross | N Engl J Med | 1999 | 9887164 | No |
28 | 16795 | 16795.0 | 636.46 | 636.5 | Disc Electrophoresis. Ii. Method And Application To Human Serum Proteins. | B J Davis | Ann N Y Acad Sci | 1964 | 14240539 | Yes |
29 | 16279 | 16279.0 | 706.06 | 706.1 | RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies. | Alexandros Stamatakis | Bioinformatics | 2014 | 24451623 | Yes |
30 | 16193 | 16193.0 | 447.67 | 447.7 | High resolution two-dimensional electrophoresis of proteins. | P H O'Farrell | J Biol Chem | 1975 | 236308 | Yes |
31 | 32131 | 16065.5 | 0.0 | 0.0 | A rapid method of total lipid extraction and purification. | E G Bligh, W J Dyer | Can J Biochem Physiol | 1959 | 13671378 | Yes |
32 | 15942 | 15942.0 | 0.0 | 0.0 | A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. | K Burton | Biochem J | 1956 | 13293190 | Yes |
33 | 15861 | 15861.0 | 652.52 | 652.5 | A power primer. | J Cohen | Psychol Bull | 1992 | 19565683 | Yes |
34 | 15228 | 15228.0 | 385.1 | 385.1 | MicroRNAs: target recognition and regulatory functions. | David P Bartel | Cell | 2009 | 19167326 | No |
35 | 45181 | 15060.3 | 1289.53 | 429.8 | CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. | J D Thompson, D G Higgins, T J Gibson | Nucleic Acids Res | 1994 | 7984417 | Yes |
36 | 44836 | 14945.3 | 1330.82 | 443.6 | Generalized Gradient Approximation Made Simple. | J P Perdew, K Burke, M Ernzerhof | Phys Rev Lett | 1996 | 10062328 | Yes |
37 | 29586 | 14793.0 | 1184.67 | 592.3 | The hospital anxiety and depression scale. | A S Zigmond, R P Snaith | Acta Psychiatr Scand | 1983 | 6880820 | Yes |
38 | 29362 | 14681.0 | 1101.73 | 550.9 | Meta-analysis in clinical trials. | R DerSimonian, N Laird | Control Clin Trials | 1986 | 3802833 | Yes |
39 | 28885 | 14442.5 | 930.46 | 465.2 | Fast gapped-read alignment with Bowtie 2. | Ben Langmead, Steven L Salzberg | Nat Methods | 2012 | 22388286 | Yes |
40 | 28488 | 14244.0 | 724.51 | 362.3 | Fast and accurate short read alignment with Burrows-Wheeler transform. | Heng Li, Richard Durbin | Bioinformatics | 2009 | 19451168 | Yes |
41 | 14218 | 14218.0 | 554.04 | 554.0 | Catalase in vitro. | H Aebi | Methods Enzymol | 1984 | 6727660 | Yes |
42 | 41513 | 13837.7 | 0.0 | 0.0 | A simple method for the isolation and purification of total lipides from animal tissues. | J Folch, M Lees, G H Sloane Stanley | J Biol Chem | 1957 | 13428781 | Yes |
43 | 40420 | 13473.3 | 1523.96 | 508.0 | Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. | Michael I Love, Wolfgang Huber, Simon Anders | Genome Biol | 2014 | 25516281 | Yes |
44 | 13042 | 13042.0 | 687.46 | 687.5 | Crystal structure refinement with SHELXL. | George M Sheldrick | Acta Crystallogr C Struct Chem | 2015 | 25567568 | Yes |
45 | 12612 | 12612.0 | 0.0 | 0.0 | Phosphorus assay in column chromatography. | G R Bartlett | J Biol Chem | 1959 | 13641241 | Yes |
46 | 62187 | 12437.4 | 1779.08 | 355.8 | Basic local alignment search tool. | S F Altschul, W Gish, W Miller, E W Myers, D J Lipman | J Mol Biol | 1990 | 2231712 | Yes |
47 | 24507 | 12253.5 | 507.63 | 253.8 | Coot: model-building tools for molecular graphics. | Paul Emsley, Kevin Cowtan | Acta Crystallogr D Biol Crystallogr | 2004 | 15572765 | Yes |
48 | 36745 | 12248.3 | 1302.95 | 434.3 | Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density. | C Lee, W Yang, R G Parr | Phys Rev B Condens Matter | 1988 | 9944570 | Yes |
49 | 12190 | 12190.0 | 396.6 | 396.6 | Search and clustering orders of magnitude faster than BLAST. | Robert C Edgar | Bioinformatics | 2010 | 20709691 | Yes |
50 | 24333 | 12166.5 | 998.92 | 499.5 | The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. | J E Ware, C D Sherbourne | Med Care | 1992 | 1593914 | Yes |
51 | 24089 | 12044.5 | 527.92 | 264.0 | Processing of X-ray diffraction data collected in oscillation mode. | Z Otwinowski, W Minor | Methods Enzymol | 1997 | 27754618 | Yes |
52 | 11910 | 11910.0 | 307.77 | 307.8 | Xds. | Wolfgang Kabsch | Acta Crystallogr D Biol Crystallogr | 2010 | 20124692 | Yes |
53 | 23724 | 11862.0 | 652.53 | 326.3 | Efficient iterative schemes for ab initio total-energy calculations using a plane-wave basis set. | G Kresse, J Furthmüller | Phys Rev B Condens Matter | 1996 | 9984901 | Yes |
54 | 11775 | 11775.0 | 134.22 | 134.2 | The genetics of Caenorhabditis elegans. | S Brenner | Genetics | 1974 | 4366476 | Yes |
55 | 11622 | 11622.0 | 382.19 | 382.2 | Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). | J F Kurtzke | Neurology | 1983 | 6685237 | Yes |
56 | 11574 | 11574.0 | 349.88 | 349.9 | The Psychophysics Toolbox. | D H Brainard | Spat Vis | 1997 | 9176952 | Yes |
57 | 23080 | 11540.0 | 624.89 | 312.4 | Quantifying heterogeneity in a meta-analysis. | Julian P T Higgins, Simon G Thompson | Stat Med | 2002 | 12111919 | Yes |
58 | 11490 | 11490.0 | 537.93 | 537.9 | Self-efficacy: toward a unifying theory of behavioral change. | A Bandura | Psychol Rev | 1977 | 847061 | Yes |
59 | 21588 | 10794.0 | 558.62 | 279.3 | A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. | A P Feinberg, B Vogelstein | Anal Biochem | 1983 | 6312838 | Yes |
60 | 10729 | 10729.0 | 410.39 | 410.4 | A new method for measuring daytime sleepiness: the Epworth sleepiness scale. | M W Johns | Sleep | 1991 | 1798888 | Yes |
61 | 21033 | 10516.5 | 460.8 | 230.4 | [20] Processing of X-ray diffraction data collected in oscillation mode. | Zbyszek Otwinowski, Wladek Minor | Methods Enzymol | 1997 | 27799103 | Yes |
62 | 10509 | 10509.0 | 365.6 | 365.6 | Structure validation in chemical crystallography. | Anthony L Spek | Acta Crystallogr D Biol Crystallogr | 2009 | 19171970 | Yes |
63 | 10390 | 10390.0 | 365.08 | 365.1 | Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. | Andreas Stang | Eur J Epidemiol | 2010 | 20652370 | Yes |
64 | 31053 | 10351.0 | 1238.02 | 412.7 | Trimmomatic: a flexible trimmer for Illumina sequence data. | Anthony M Bolger, Marc Lohse, Bjoern Usadel | Bioinformatics | 2014 | 24695404 | Yes |
65 | 10307 | 10307.0 | 202.69 | 202.7 | Improvements in epoxy resin embedding methods. | J H Luft | J Biophys Biochem Cytol | 1961 | 13764136 | Yes |
66 | 30833 | 10277.7 | 802.05 | 267.3 | VMD: visual molecular dynamics. | W Humphrey, A Dalke, K Schulten | J Mol Graph | 1996 | 8744570 | Yes |
67 | 10176 | 10176.0 | 415.0 | 415.0 | Investigation of the freely available easy-to-use software 'EZR' for medical statistics. | Y Kanda | Bone Marrow Transplant | 2013 | 23208313 | Yes |
68 | 20304 | 10152.0 | 876.68 | 438.3 | The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. | R M Baron, D A Kenny | J Pers Soc Psychol | 1986 | 3806354 | Yes |
69 | 40492 | 10123.0 | 1575.52 | 393.9 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | PLoS Med | 2009 | 19621072 | No |
70 | 40163 | 10040.8 | 1150.39 | 287.6 | Measuring inconsistency in meta-analyses. | Julian P T Higgins, Simon G Thompson, Jonathan J Deeks, Douglas G Altman | BMJ | 2003 | 12958120 | No |
71 | 19791 | 9895.5 | 402.09 | 201.0 | The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. | K Weber, M Osborn | J Biol Chem | 1969 | 5806584 | Yes |
72 | 29682 | 9894.0 | 1014.44 | 338.1 | NIH Image to ImageJ: 25 years of image analysis. | Caroline A Schneider, Wayne S Rasband, Kevin W Eliceiri | Nat Methods | 2012 | 22930834 | No |
73 | 19770 | 9885.0 | 769.75 | 384.9 | MAFFT multiple sequence alignment software version 7: improvements in performance and usability. | Kazutaka Katoh, Daron M Standley | Mol Biol Evol | 2013 | 23329690 | Yes |
74 | 9769 | 9769.0 | 0.0 | 0.0 | On the origin of cancer cells. | O Warburg | Science | 1956 | 13298683 | Yes |
75 | 9614 | 9614.0 | 322.61 | 322.6 | Banting lecture 1988. Role of insulin resistance in human disease. | G M Reaven | Diabetes | 1988 | 3056758 | No |
76 | 9539 | 9539.0 | 268.49 | 268.5 | Evolutionary trees from DNA sequences: a maximum likelihood approach. | J Felsenstein | J Mol Evol | 1981 | 7288891 | Yes |
77 | 19003 | 9501.5 | 409.95 | 205.0 | KEGG: kyoto encyclopedia of genes and genomes. | M Kanehisa, S Goto | Nucleic Acids Res | 2000 | 10592173 | Yes |
78 | 18912 | 9456.0 | 487.7 | 243.8 | A simple method for displaying the hydropathic character of a protein. | J Kyte, R F Doolittle | J Mol Biol | 1982 | 7108955 | Yes |
79 | 9432 | 9432.0 | 197.03 | 197.0 | Mfold web server for nucleic acid folding and hybridization prediction. | Michael Zuker | Nucleic Acids Res | 2003 | 12824337 | Yes |
80 | 9366 | 9366.0 | 250.7 | 250.7 | Semiempirical GGA-type density functional constructed with a long-range dispersion correction. | Stefan Grimme | J Comput Chem | 2006 | 16955487 | Yes |
81 | 9337 | 9337.0 | 246.91 | 246.9 | Studies on transformation of Escherichia coli with plasmids. | D Hanahan | J Mol Biol | 1983 | 6345791 | Yes |
82 | 9262 | 9262.0 | 262.99 | 263.0 | Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. | P S Thomas | Proc Natl Acad Sci U S A | 1980 | 6159641 | Yes |
83 | 9242 | 9242.0 | 398.26 | 398.3 | Psychophysical bases of perceived exertion. | G A Borg | Med Sci Sports Exerc | 1982 | 7154893 | Yes |
84 | 9209 | 9209.0 | 267.43 | 267.4 | Vitamin D deficiency. | Michael F Holick | N Engl J Med | 2007 | 17634462 | No |
85 | 9191 | 9191.0 | 239.06 | 239.1 | RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. | Alexandros Stamatakis | Bioinformatics | 2006 | 16928733 | Yes |
86 | 9178 | 9178.0 | 259.45 | 259.4 | The pathogenesis of atherosclerosis: a perspective for the 1990s. | R Ross | Nature | 1993 | 8479518 | No |
87 | 9070 | 9070.0 | 234.05 | 234.1 | Integrins: versatility, modulation, and signaling in cell adhesion. | R O Hynes | Cell | 1992 | 1555235 | No |
88 | 18129 | 9064.5 | 381.5 | 190.8 | The hallmarks of cancer. | D Hanahan, R A Weinberg | Cell | 2000 | 10647931 | No |
89 | 8983 | 8983.0 | 266.14 | 266.1 | The blockade of immune checkpoints in cancer immunotherapy. | Drew M Pardoll | Nat Rev Cancer | 2012 | 22437870 | No |
90 | 35719 | 8929.8 | 1312.62 | 328.2 | A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. | M E Charlson, P Pompei, K L Ales, C R MacKenzie | J Chronic Dis | 1987 | 3558716 | Yes |
91 | 8821 | 8821.0 | 407.77 | 407.8 | Prokka: rapid prokaryotic genome annotation. | Torsten Seemann | Bioinformatics | 2014 | 24642063 | Yes |
92 | 8797 | 8797.0 | 178.45 | 178.4 | Linear models and empirical bayes methods for assessing differential expression in microarray experiments. | Gordon K Smyth | Stat Appl Genet Mol Biol | 2004 | 16646809 | Yes |
93 | 26082 | 8694.0 | 672.92 | 224.3 | Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. | Da Wei Huang, Brad T Sherman, Richard A Lempicki | Nat Protoc | 2009 | 19131956 | Yes |
94 | 34276 | 8569.0 | 1106.49 | 276.6 | Bias in meta-analysis detected by a simple, graphical test. | M Egger, G Davey Smith, M Schneider, C Minder | BMJ | 1997 | 9310563 | Yes |
95 | 8554 | 8554.0 | 222.36 | 222.4 | Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. | M C Hochberg | Arthritis Rheum | 1997 | 9324032 | Yes |
96 | 17096 | 8548.0 | 452.37 | 226.2 | Analyzing real-time PCR data by the comparative C(T) method. | Thomas D Schmittgen, Kenneth J Livak | Nat Protoc | 2008 | 18546601 | Yes |
97 | 8485 | 8485.0 | 0.0 | 0.0 | Copper Enzymes In Isolated Chloroplasts. Polyphenoloxidase In Beta Vulgaris. | D I Arnon | Plant Physiol | 1949 | 16654194 | Yes |
98 | 8474 | 8474.0 | 180.0 | 180.0 | The functions of animal microRNAs. | Victor Ambros | Nature | 2004 | 15372042 | No |
99 | 16943 | 8471.5 | 373.26 | 186.6 | Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. | Kazutoshi Takahashi, Shinya Yamanaka | Cell | 2006 | 16904174 | Yes |
100 | 8409 | 8409.0 | 203.93 | 203.9 | PAML 4: phylogenetic analysis by maximum likelihood. | Ziheng Yang | Mol Biol Evol | 2007 | 17483113 | Yes |
101 | 50386 | 8397.7 | 3506.11 | 584.4 | Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. | Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal | CA Cancer J Clin | 2018 | 30207593 | Yes |
102 | 8372 | 8372.0 | 220.21 | 220.2 | Canonical dynamics: Equilibrium phase-space distributions. | W G Hoover | Phys Rev A Gen Phys | 1985 | 9895674 | Yes |
103 | 8110 | 8110.0 | 0.0 | 0.0 | The assessment of anxiety states by rating. | M Hamilton | Br J Med Psychol | 1959 | 13638508 | Yes |
104 | 8081 | 8081.0 | 176.51 | 176.5 | Solvent content of protein crystals. | B W Matthews | J Mol Biol | 1968 | 5700707 | Yes |
105 | 7997 | 7997.0 | 210.32 | 210.3 | Apoptosis: a review of programmed cell death. | Susan Elmore | Toxicol Pathol | 2007 | 17562483 | No |
106 | 7987 | 7987.0 | 410.16 | 410.2 | SHELXT - integrated space-group and crystal-structure determination. | George M Sheldrick | Acta Crystallogr A Found Adv | 2015 | 25537383 | Yes |
107 | 23907 | 7969.0 | 1374.67 | 458.2 | MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets. | Sudhir Kumar, Glen Stecher, Koichiro Tamura | Mol Biol Evol | 2016 | 27004904 | Yes |
108 | 7961 | 7961.0 | 234.41 | 234.4 | AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. | R W Cox | Comput Biomed Res | 1996 | 8812068 | Yes |
109 | 7958 | 7958.0 | 343.69 | 343.7 | UPARSE: highly accurate OTU sequences from microbial amplicon reads. | Robert C Edgar | Nat Methods | 2013 | 23955772 | Yes |
110 | 7866 | 7866.0 | 217.57 | 217.6 | "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. | W N Burnette | Anal Biochem | 1981 | 6266278 | Yes |
111 | 7811 | 7811.0 | 216.46 | 216.5 | The role of protein kinase C in cell surface signal transduction and tumour promotion. | Y Nishizuka | Nature | 1984 | 6232463 | No |
112 | 7789 | 7789.0 | 225.13 | 225.1 | A simplification of the protein assay method of Lowry et al. which is more generally applicable. | G L Peterson | Anal Biochem | 1977 | 603028 | Yes |
113 | 23327 | 7775.7 | 626.31 | 208.8 | edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. | Mark D Robinson, Davis J McCarthy, Gordon K Smyth | Bioinformatics | 2010 | 19910308 | Yes |
114 | 7759 | 7759.0 | 358.93 | 358.9 | Comparative fit indexes in structural models. | P M Bentler | Psychol Bull | 1990 | 2320703 | Yes |
115 | 15460 | 7730.0 | 377.76 | 188.9 | MrBayes 3: Bayesian phylogenetic inference under mixed models. | Fredrik Ronquist, John P Huelsenbeck | Bioinformatics | 2003 | 12912839 | Yes |
116 | 7653 | 7653.0 | 205.53 | 205.5 | Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. | F Tajima | Genetics | 1989 | 2513255 | Yes |
117 | 7653 | 7653.0 | 156.5 | 156.5 | Tumor angiogenesis: therapeutic implications. | J Folkman | N Engl J Med | 1971 | 4938153 | No |
118 | 7644 | 7644.0 | 226.54 | 226.5 | Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. | J R Vane | Nat New Biol | 1971 | 5284360 | Yes |
119 | 7584 | 7584.0 | 251.99 | 252.0 | Density-functional approximation for the correlation energy of the inhomogeneous electron gas. | J P Perdew | Phys Rev B Condens Matter | 1986 | 9938299 | Yes |
120 | 7575 | 7575.0 | 204.07 | 204.1 | Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. | A Böyum | Scand J Clin Lab Invest Suppl | 1968 | 4179068 | Yes |
121 | 15092 | 7546.0 | 338.52 | 169.3 | Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana. | S J Clough, A F Bent | Plant J | 1998 | 10069079 | Yes |
122 | 22433 | 7477.7 | 660.4 | 220.1 | The PHQ-9: validity of a brief depression severity measure. | K Kroenke, R L Spitzer, J B Williams | J Gen Intern Med | 2001 | 11556941 | Yes |
123 | 7468 | 7468.0 | 160.18 | 160.2 | Chromatin modifications and their function. | Tony Kouzarides | Cell | 2007 | 17320507 | No |
124 | 7430 | 7430.0 | 183.9 | 183.9 | Fast robust automated brain extraction. | Stephen M Smith | Hum Brain Mapp | 2002 | 12391568 | No |
125 | 22205 | 7401.7 | 838.89 | 279.6 | Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. | W T Friedewald, R I Levy, D S Fredrickson | Clin Chem | 1972 | 4337382 | Yes |
126 | 7356 | 7356.0 | 134.4 | 134.4 | A low-viscosity epoxy resin embedding medium for electron microscopy. | A R Spurr | J Ultrastruct Res | 1969 | 4887011 | Yes |
127 | 51174 | 7310.6 | 1318.89 | 188.4 | Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. | S F Altschul, T L Madden, A A Schäffer, J Zhang, Z Zhang, W Miller, D J Lipman | Nucleic Acids Res | 1997 | 9254694 | No |
128 | 14316 | 7158.0 | 482.61 | 241.3 | Three approaches to qualitative content analysis. | Hsiu-Fang Hsieh, Sarah E Shannon | Qual Health Res | 2005 | 16204405 | Yes |
129 | 21342 | 7114.0 | 649.64 | 216.5 | Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. | Daniel Dindo, Nicolas Demartines, Pierre-Alain Clavien | Ann Surg | 2004 | 15273542 | Yes |
130 | 14211 | 7105.5 | 443.19 | 221.6 | AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. | Oleg Trott, Arthur J Olson | J Comput Chem | 2010 | 19499576 | Yes |
131 | 7048 | 7048.0 | 213.08 | 213.1 | The VideoToolbox software for visual psychophysics: transforming numbers into movies. | D G Pelli | Spat Vis | 1997 | 9176953 | Yes |
132 | 7043 | 7043.0 | 191.22 | 191.2 | TreeView: an application to display phylogenetic trees on personal computers. | R D Page | Comput Appl Biosci | 1996 | 8902363 | Yes |
133 | 7027 | 7027.0 | 222.75 | 222.8 | The Clinical Dementia Rating (CDR): current version and scoring rules. | J C Morris | Neurology | 1993 | 8232972 | Yes |
134 | 13825 | 6912.5 | 331.98 | 166.0 | BEDTools: a flexible suite of utilities for comparing genomic features. | Aaron R Quinlan, Ira M Hall | Bioinformatics | 2010 | 20110278 | Yes |
135 | 13817 | 6908.5 | 353.81 | 176.9 | Continuous cultures of fused cells secreting antibody of predefined specificity. | G Köhler, C Milstein | Nature | 1975 | 1172191 | Yes |
136 | 6858 | 6858.0 | 184.63 | 184.6 | The steroid and thyroid hormone receptor superfamily. | R M Evans | Science | 1988 | 3283939 | No |
137 | 6761 | 6761.0 | 237.37 | 237.4 | The Strengths and Difficulties Questionnaire: a research note. | R Goodman | J Child Psychol Psychiatry | 1997 | 9255702 | Yes |
138 | 26929 | 6732.2 | 885.76 | 221.4 | G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. | Franz Faul, Edgar Erdfelder, Albert-Georg Lang, Axel Buchner | Behav Res Methods | 2007 | 17695343 | Yes |
139 | 6696 | 6696.0 | 0.0 | 0.0 | The thiobarbituric acid assay of sialic acids. | L Warren | J Biol Chem | 1959 | 13672998 | Yes |
140 | 6576 | 6576.0 | 172.32 | 172.3 | Adhesion receptors of the immune system. | T A Springer | Nature | 1990 | 1974032 | No |
141 | 13114 | 6557.0 | 309.31 | 154.7 | Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. | Y Cheng, W H Prusoff | Biochem Pharmacol | 1973 | 4202581 | Yes |
142 | 19612 | 6537.3 | 549.0 | 183.0 | A new generation of Ca2+ indicators with greatly improved fluorescence properties. | G Grynkiewicz, M Poenie, R Y Tsien | J Biol Chem | 1985 | 3838314 | Yes |
143 | 6533 | 6533.0 | 213.24 | 213.2 | Ethical guidelines for investigations of experimental pain in conscious animals. | Manfred Zimmermann | Pain | 1983 | 6877845 | No |
144 | 6517 | 6517.0 | 168.96 | 169.0 | Angiogenesis in cancer, vascular, rheumatoid and other disease. | J Folkman | Nat Med | 1995 | 7584949 | No |
145 | 12928 | 6464.0 | 699.25 | 349.6 | Intraclass correlations: uses in assessing rater reliability. | P E Shrout, J L Fleiss | Psychol Bull | 1979 | 18839484 | No |
146 | 6458 | 6458.0 | 128.43 | 128.4 | Integrins: bidirectional, allosteric signaling machines. | Richard O Hynes | Cell | 2002 | 12297042 | No |
147 | 12914 | 6457.0 | 0.0 | 0.0 | Statistical aspects of the analysis of data from retrospective studies of disease. | N Mantel, W Haenszel | J Natl Cancer Inst | 1959 | 13655060 | Yes |
148 | 6391 | 6391.0 | 128.74 | 128.7 | Rapid and efficient site-specific mutagenesis without phenotypic selection. | T A Kunkel | Proc Natl Acad Sci U S A | 1985 | 3881765 | Yes |
149 | 6357 | 6357.0 | 168.74 | 168.7 | A modified poisson regression approach to prospective studies with binary data. | Guangyong Zou | Am J Epidemiol | 2004 | 15033648 | Yes |
150 | 6342 | 6342.0 | 135.74 | 135.7 | p53, the cellular gatekeeper for growth and division. | A J Levine | Cell | 1997 | 9039259 | No |
151 | 6309 | 6309.0 | 149.22 | 149.2 | Inflammation, atherosclerosis, and coronary artery disease. | Göran K Hansson | N Engl J Med | 2005 | 15843671 | No |
152 | 12525 | 6262.5 | 347.51 | 173.8 | EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis. | Arnaud Delorme, Scott Makeig | J Neurosci Methods | 2004 | 15102499 | Yes |
153 | 12511 | 6255.5 | 500.48 | 250.2 | Prediction of creatinine clearance from serum creatinine. | D W Cockcroft, M H Gault | Nephron | 1976 | 1244564 | Yes |
154 | 6244 | 6244.0 | 111.5 | 111.5 | A Self-Rating Depression Scale. | W W Zung | Arch Gen Psychiatry | 1965 | 14221692 | Yes |
155 | 12428 | 6214.0 | 426.09 | 213.0 | The meaning and use of the area under a receiver operating characteristic (ROC) curve. | J A Hanley, B J McNeil | Radiology | 1982 | 7063747 | Yes |
156 | 6178 | 6178.0 | 135.19 | 135.2 | Inflammation in atherosclerosis. | Peter Libby | Nature | 2002 | 12490960 | No |
157 | 6149 | 6149.0 | 144.07 | 144.1 | Free radicals in the physiological control of cell function. | Wulf Dröge | Physiol Rev | 2002 | 11773609 | No |
158 | 6140 | 6140.0 | 144.93 | 144.9 | Biochemistry and molecular cell biology of diabetic complications. | M Brownlee | Nature | 2001 | 11742414 | Yes |
159 | 12250 | 6125.0 | 431.07 | 215.5 | A rapid alkaline extraction procedure for screening recombinant plasmid DNA. | H C Birnboim, J Doly | Nucleic Acids Res | 1979 | 388356 | Yes |
160 | 6117 | 6117.0 | 149.69 | 149.7 | Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. | T A Springer | Cell | 1994 | 7507411 | No |
161 | 6066 | 6066.0 | 0.0 | 0.0 | Index for rating diagnostic tests. | W J Youden | Cancer | 1950 | 15405679 | Yes |
162 | 18131 | 6043.7 | 894.16 | 298.1 | Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. | H Ohkawa, N Ohishi, K Yagi | Anal Biochem | 1979 | 36810 | Yes |
163 | 6039 | 6039.0 | 152.35 | 152.3 | Inositol trisphosphate and calcium signalling. | M J Berridge | Nature | 1993 | 8381210 | No |
164 | 6036 | 6036.0 | 138.94 | 138.9 | Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis. | J Castresana | Mol Biol Evol | 2000 | 10742046 | Yes |
165 | 6025 | 6025.0 | 153.0 | 153.0 | G proteins: transducers of receptor-generated signals. | A G Gilman | Annu Rev Biochem | 1987 | 3113327 | No |
166 | 6006 | 6006.0 | 112.98 | 113.0 | BLAT--the BLAST-like alignment tool. | W James Kent | Genome Res | 2002 | 11932250 | Yes |
167 | 24005 | 6001.2 | 767.25 | 191.8 | Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. | J M Chirgwin, A E Przybyla, R J MacDonald, W J Rutter | Biochemistry | 1979 | 518835 | Yes |
168 | 5975 | 5975.0 | 208.79 | 208.8 | An Introduction to Propensity Score Methods for Reducing the Effects of Confounding in Observational Studies. | Peter C Austin | Multivariate Behav Res | 2011 | 21818162 | Yes |
169 | 11925 | 5962.5 | 282.08 | 141.0 | WGCNA: an R package for weighted correlation network analysis. | Peter Langfelder, Steve Horvath | BMC Bioinformatics | 2008 | 19114008 | Yes |
170 | 5893 | 5893.0 | 142.86 | 142.9 | Inflammation and metabolic disorders. | Gökhan S Hotamisligil | Nature | 2006 | 17167474 | No |
171 | 11780 | 5890.0 | 285.83 | 142.9 | MRBAYES: Bayesian inference of phylogenetic trees. | J P Huelsenbeck, F Ronquist | Bioinformatics | 2001 | 11524383 | Yes |
172 | 5853 | 5853.0 | 135.44 | 135.4 | Antimicrobial peptides of multicellular organisms. | Michael Zasloff | Nature | 2002 | 11807545 | Yes |
173 | 11585 | 5792.5 | 326.78 | 163.4 | RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. | Bo Li, Colin N Dewey | BMC Bioinformatics | 2011 | 21816040 | Yes |
174 | 11498 | 5749.0 | 265.07 | 132.5 | Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features. | W Kabsch, C Sander | Biopolymers | 1983 | 6667333 | Yes |
175 | 5741 | 5741.0 | 171.34 | 171.3 | Modification of seizure activity by electrical stimulation. II. Motor seizure. | R J Racine | Electroencephalogr Clin Neurophysiol | 1972 | 4110397 | Yes |
176 | 5724 | 5724.0 | 143.08 | 143.1 | Apoptosis in the pathogenesis and treatment of disease. | C B Thompson | Science | 1995 | 7878464 | No |
177 | 11402 | 5701.0 | 252.13 | 126.1 | Dendritic cells and the control of immunity. | J Banchereau, R M Steinman | Nature | 1998 | 9521319 | No |
178 | 11379 | 5689.5 | 434.26 | 217.1 | The Carbon Monoxide-Binding Pigment Of Liver Microsomes. I. Evidence For Its Hemoprotein Nature. | T Omura, R Sato | J Biol Chem | 1964 | 14209971 | Yes |
179 | 11338 | 5669.0 | 248.34 | 124.2 | One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. | K A Datsenko, B L Wanner | Proc Natl Acad Sci U S A | 2000 | 10829079 | Yes |
180 | 11324 | 5662.0 | 308.98 | 154.5 | Neuropathological stageing of Alzheimer-related changes. | H Braak, E Braak | Acta Neuropathol | 1991 | 1759558 | No |
181 | 5649 | 5649.0 | 74.09 | 74.1 | The Environment And Disease: Association Or Causation? | A B Hill | Proc R Soc Med | 1965 | 14283879 | Yes |
182 | 11203 | 5601.5 | 0.0 | 0.0 | A series of normal stages in the development of the chick embryo. | V Hamburger, H L Hamilton | J Morphol | 1951 | 24539719 | Yes |
183 | 39117 | 5588.1 | 6816.35 | 973.8 | Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. | Hyuna Sung, Jacques Ferlay, Rebecca L Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, Freddie Bray | CA Cancer J Clin | 2021 | 33538338 | Yes |
184 | 5559 | 5559.0 | 0.0 | 0.0 | Aging: a theory based on free radical and radiation chemistry. | D Harman | J Gerontol | 1956 | 13332224 | Yes |
185 | 5556 | 5556.0 | 176.68 | 176.7 | jModelTest: phylogenetic model averaging. | David Posada | Mol Biol Evol | 2008 | 18397919 | Yes |
186 | 5549 | 5549.0 | 100.5 | 100.5 | Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. | F Tietze | Anal Biochem | 1969 | 4388022 | Yes |
187 | 5525 | 5525.0 | 155.08 | 155.1 | A fast diffeomorphic image registration algorithm. | John Ashburner | Neuroimage | 2007 | 17761438 | Yes |
188 | 11045 | 5522.5 | 289.86 | 144.9 | Sequencing end-labeled DNA with base-specific chemical cleavages. | A M Maxam, W Gilbert | Methods Enzymol | 1980 | 6246368 | Yes |
189 | 5521 | 5521.0 | 133.17 | 133.2 | Development of a rating scale for primary depressive illness. | M Hamilton | Br J Soc Clin Psychol | 1967 | 6080235 | Yes |
190 | 5511 | 5511.0 | 119.93 | 119.9 | The biochemistry of apoptosis. | M O Hengartner | Nature | 2000 | 11048727 | No |
191 | 5491 | 5491.0 | 122.05 | 122.0 | MUSCLE: a multiple sequence alignment method with reduced time and space complexity. | Robert C Edgar | BMC Bioinformatics | 2004 | 15318951 | Yes |
192 | 5473 | 5473.0 | 216.81 | 216.8 | Orienting of attention. | M I Posner | Q J Exp Psychol | 1980 | 7367577 | Yes |
193 | 5468 | 5468.0 | 105.43 | 105.4 | Evaluation of survival data and two new rank order statistics arising in its consideration. | N Mantel | Cancer Chemother Rep | 1966 | 5910392 | Yes |
194 | 5463 | 5463.0 | 95.84 | 95.8 | Mutation and cancer: statistical study of retinoblastoma. | A G Knudson | Proc Natl Acad Sci U S A | 1971 | 5279523 | Yes |
195 | 10924 | 5462.0 | 254.54 | 127.3 | A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. | Stéphane Guindon, Olivier Gascuel | Syst Biol | 2003 | 14530136 | Yes |
196 | 16338 | 5446.0 | 491.38 | 163.8 | A simple salting out procedure for extracting DNA from human nucleated cells. | S A Miller, D D Dykes, H F Polesky | Nucleic Acids Res | 1988 | 3344216 | Yes |
197 | 10876 | 5438.0 | 288.91 | 144.5 | Balanced basis sets of split valence, triple zeta valence and quadruple zeta valence quality for H to Rn: Design and assessment of accuracy. | Florian Weigend, Reinhart Ahlrichs | Phys Chem Chem Phys | 2005 | 16240044 | Yes |
198 | 5357 | 5357.0 | 138.44 | 138.4 | The Cambridge Structural Database: a quarter of a million crystal structures and rising. | Frank H Allen | Acta Crystallogr B | 2002 | 12037359 | Yes |
199 | 10699 | 5349.5 | 299.06 | 149.5 | MODELTEST: testing the model of DNA substitution. | D Posada, K A Crandall | Bioinformatics | 1998 | 9918953 | Yes |
200 | 10688 | 5344.0 | 227.23 | 113.6 | Inflammation and cancer. | Lisa M Coussens, Zena Werb | Nature | 2002 | 12490959 | No |
201 | 10677 | 5338.5 | 750.38 | 375.2 | A Guideline of Selecting and Reporting Intraclass Correlation Coefficients for Reliability Research. | Terry K Koo, Mae Y Li | J Chiropr Med | 2016 | 27330520 | Yes |
202 | 5312 | 5312.0 | 135.07 | 135.1 | New M13 vectors for cloning. | J Messing | Methods Enzymol | 1983 | 6310323 | Yes |
203 | 5292 | 5292.0 | 156.77 | 156.8 | Developments of a water-maze procedure for studying spatial learning in the rat. | R Morris | J Neurosci Methods | 1984 | 6471907 | Yes |
204 | 5292 | 5292.0 | 127.7 | 127.7 | The NF-kappa B and I kappa B proteins: new discoveries and insights. | A S Baldwin | Annu Rev Immunol | 1996 | 8717528 | No |
205 | 10564 | 5282.0 | 1034.38 | 517.2 | Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. | Zunyou Wu, Jennifer M McGoogan | JAMA | 2020 | 32091533 | Yes |
206 | 5280 | 5280.0 | 152.61 | 152.6 | Studies and perspectives of protein kinase C. | Y Nishizuka | Science | 1986 | 3014651 | No |
207 | 26396 | 5279.2 | 712.08 | 142.4 | The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. | J D Thompson, T J Gibson, F Plewniak, F Jeanmougin, D G Higgins | Nucleic Acids Res | 1997 | 9396791 | Yes |
208 | 15780 | 5260.0 | 560.29 | 186.8 | Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. | Allison Tong, Peter Sainsbury, Jonathan Craig | Int J Qual Health Care | 2007 | 17872937 | Yes |
209 | 10478 | 5239.0 | 271.12 | 135.6 | Differential expression analysis for sequence count data. | Simon Anders, Wolfgang Huber | Genome Biol | 2010 | 20979621 | Yes |
210 | 5235 | 5235.0 | 102.36 | 102.4 | Epithelial-mesenchymal transitions in tumour progression. | Jean Paul Thiery | Nat Rev Cancer | 2002 | 12189386 | No |
211 | 5221 | 5221.0 | 0.0 | 0.0 | [A micro-method of immuno-electrophoresis]. | J J Scheidegger | Int Arch Allergy Appl Immunol | 1955 | 13262900 | Yes |
212 | 10437 | 5218.5 | 345.7 | 172.8 | Operating characteristics of a rank correlation test for publication bias. | C B Begg, M Mazumdar | Biometrics | 1994 | 7786990 | Yes |
213 | 10425 | 5212.5 | 0.0 | 0.0 | A quantitative description of membrane current and its application to conduction and excitation in nerve. | A L Hodgkin, A F Huxley | J Physiol | 1952 | 12991237 | Yes |
214 | 5211 | 5211.0 | 189.03 | 189.0 | Oxygen-derived free radicals in postischemic tissue injury. | J M McCord | N Engl J Med | 1985 | 2981404 | No |
215 | 5203 | 5203.0 | 172.72 | 172.7 | Whatever happened to qualitative description? | M Sandelowski | Res Nurs Health | 2000 | 10940958 | No |
216 | 5189 | 5189.0 | 66.09 | 66.1 | Selective extraction of polyoma DNA from infected mouse cell cultures. | B Hirt | J Mol Biol | 1967 | 4291934 | Yes |
217 | 15537 | 5179.0 | 584.35 | 194.8 | The positive and negative syndrome scale (PANSS) for schizophrenia. | S R Kay, A Fiszbein, L A Opler | Schizophr Bull | 1987 | 3616518 | Yes |
218 | 10355 | 5177.5 | 482.73 | 241.4 | A new depression scale designed to be sensitive to change. | S A Montgomery, M Asberg | Br J Psychiatry | 1979 | 444788 | Yes |
219 | 5163 | 5163.0 | 136.64 | 136.6 | Mild cognitive impairment as a diagnostic entity. | R C Petersen | J Intern Med | 2004 | 15324362 | No |
220 | 10307 | 5153.5 | 365.25 | 182.6 | The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. | R F Furchgott, J V Zawadzki | Nature | 1980 | 6253831 | Yes |
221 | 5139 | 5139.0 | 52.87 | 52.9 | The Two Histological Main Types Of Gastric Carcinoma: Diffuse And So-Called Intestinal-Type Carcinoma. An Attempt At A Histo-Clinical Classification. | P Lauren | Acta Pathol Microbiol Scand | 1965 | 14320675 | Yes |
222 | 5117 | 5117.0 | 187.42 | 187.4 | Analyzing Tables Of Statistical Tests. | William R Rice | Evolution | 1989 | 28568501 | Yes |
223 | 10214 | 5107.0 | 271.53 | 135.8 | Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. | H Schägger, G von Jagow | Anal Biochem | 1987 | 2449095 | Yes |
224 | 5102 | 5102.0 | 157.08 | 157.1 | Prejudice, social stress, and mental health in lesbian, gay, and bisexual populations: conceptual issues and research evidence. | Ilan H Meyer | Psychol Bull | 2003 | 12956539 | No |
225 | 5099 | 5099.0 | 101.75 | 101.8 | Rho GTPases and the actin cytoskeleton. | A Hall | Science | 1998 | 9438836 | No |
226 | 5082 | 5082.0 | 139.79 | 139.8 | How mitochondria produce reactive oxygen species. | Michael P Murphy | Biochem J | 2009 | 19061483 | No |
227 | 5079 | 5079.0 | 124.16 | 124.2 | Emotion circuits in the brain. | J E LeDoux | Annu Rev Neurosci | 2000 | 10845062 | No |
228 | 15224 | 5074.7 | 375.7 | 125.2 | Inference of population structure using multilocus genotype data. | J K Pritchard, M Stephens, P Donnelly | Genetics | 2000 | 10835412 | Yes |
229 | 10122 | 5061.0 | 241.04 | 120.5 | Comparative protein modelling by satisfaction of spatial restraints. | A Sali, T L Blundell | J Mol Biol | 1993 | 8254673 | Yes |
230 | 5037 | 5037.0 | 192.21 | 192.2 | Revisiting the behavioral model and access to medical care: does it matter? | R M Andersen | J Health Soc Behav | 1995 | 7738325 | Yes |
231 | 10064 | 5032.0 | 218.91 | 109.5 | The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. | John Hardy, Dennis J Selkoe | Science | 2002 | 12130773 | No |
232 | 5026 | 5026.0 | 228.73 | 228.7 | Interrater reliability: the kappa statistic. | Mary L McHugh | Biochem Med (Zagreb) | 2012 | 23092060 | Yes |
233 | 5017 | 5017.0 | 101.48 | 101.5 | Targeting HIF-1 for cancer therapy. | Gregg L Semenza | Nat Rev Cancer | 2003 | 13130303 | No |
234 | 9981 | 4990.5 | 220.38 | 110.2 | MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. | Jürgen Cox, Matthias Mann | Nat Biotechnol | 2008 | 19029910 | Yes |
235 | 14944 | 4981.3 | 538.39 | 179.5 | Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. | S M Hsu, L Raine, H Fanger | J Histochem Cytochem | 1981 | 6166661 | Yes |
236 | 4959 | 4959.0 | 143.67 | 143.7 | A protein binding assay for adenosine 3':5'-cyclic monophosphate. | A G Gilman | Proc Natl Acad Sci U S A | 1970 | 4318781 | Yes |
237 | 4922 | 4922.0 | 140.66 | 140.7 | Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies. | C B Laurell | Anal Biochem | 1966 | 5959431 | Yes |
238 | 24596 | 4919.2 | 1087.86 | 217.6 | MEGA6: Molecular Evolutionary Genetics Analysis version 6.0. | Koichiro Tamura, Glen Stecher, Daniel Peterson, Alan Filipski, Sudhir Kumar | Mol Biol Evol | 2013 | 24132122 | Yes |
239 | 9806 | 4903.0 | 350.12 | 175.1 | Ligand: a versatile computerized approach for characterization of ligand-binding systems. | P J Munson, D Rodbard | Anal Biochem | 1980 | 6254391 | Yes |
240 | 4900 | 4900.0 | 191.74 | 191.7 | The need for a new medical model: a challenge for biomedicine. | G L Engel | Science | 1977 | 847460 | Yes |
241 | 4897 | 4897.0 | 110.9 | 110.9 | Tandem repeats finder: a program to analyze DNA sequences. | G Benson | Nucleic Acids Res | 1999 | 9862982 | Yes |
242 | 9791 | 4895.5 | 233.77 | 116.9 | A genetic model for colorectal tumorigenesis. | E R Fearon, B Vogelstein | Cell | 1990 | 2188735 | No |
243 | 14602 | 4867.3 | 391.76 | 130.6 | Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. | C Yanisch-Perron, J Vieira, J Messing | Gene | 1985 | 2985470 | Yes |
244 | 4867 | 4867.0 | 110.13 | 110.1 | The clonal evolution of tumor cell populations. | P C Nowell | Science | 1976 | 959840 | Yes |
245 | 4848 | 4848.0 | 97.86 | 97.9 | An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs. | M Kozak | Nucleic Acids Res | 1987 | 3313277 | No |
246 | 14486 | 4828.7 | 1097.23 | 365.7 | Cancer statistics, 2019. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2019 | 30620402 | Yes |
247 | 14469 | 4823.0 | 357.35 | 119.1 | A comprehensive set of sequence analysis programs for the VAX. | J Devereux, P Haeberli, O Smithies | Nucleic Acids Res | 1984 | 6546423 | Yes |
248 | 4785 | 4785.0 | 89.94 | 89.9 | DNA methylation patterns and epigenetic memory. | Adrian Bird | Genes Dev | 2002 | 11782440 | No |
249 | 14339 | 4779.7 | 0.0 | 0.0 | Determination of serum proteins by means of the biuret reaction. | A G Gornall, C J Bardawill, M M David | J Biol Chem | 1949 | 18110453 | Yes |
250 | 19108 | 4777.0 | 494.1 | 123.5 | Features and development of Coot. | P Emsley, B Lohkamp, W G Scott, K Cowtan | Acta Crystallogr D Biol Crystallogr | 2010 | 20383002 | Yes |
251 | 4772 | 4772.0 | 128.53 | 128.5 | Metabolism Of Isolated Fat Cells. I. Effects Of Hormones On Glucose Metabolism And Lipolysis. | M Rodbell | J Biol Chem | 1964 | 14169133 | Yes |
252 | 23851 | 4770.2 | 407.54 | 81.5 | An inventory for measuring depression. | A T Beck, C H Ward, M Mendelson, J Mock, J Erbaugh | Arch Gen Psychiatry | 1961 | 13688369 | Yes |
253 | 4758 | 4758.0 | 104.3 | 104.3 | Cancer cell cycles. | C J Sherr | Science | 1996 | 8939849 | No |
254 | 9509 | 4754.5 | 159.31 | 79.7 | A new technique for the assay of infectivity of human adenovirus 5 DNA. | F L Graham, A J van der Eb | Virology | 1973 | 4705382 | Yes |
255 | 4747 | 4747.0 | 106.42 | 106.4 | ras oncogenes in human cancer: a review. | J L Bos | Cancer Res | 1989 | 2547513 | No |
256 | 4736 | 4736.0 | 157.12 | 157.1 | Traumatic arthritis of the hip after dislocation and acetabular fractures: treatment by mold arthroplasty. An end-result study using a new method of result evaluation. | W H Harris | J Bone Joint Surg Am | 1969 | 5783851 | Yes |
257 | 9472 | 4736.0 | 256.85 | 128.4 | The rise of graphene. | A K Geim, K S Novoselov | Nat Mater | 2007 | 17330084 | Yes |
258 | 9405 | 4702.5 | 237.45 | 118.7 | Improved tools for biological sequence comparison. | W R Pearson, D J Lipman | Proc Natl Acad Sci U S A | 1988 | 3162770 | Yes |
259 | 4702 | 4702.0 | 157.03 | 157.0 | The pathogenesis of atherosclerosis--an update. | R Ross | N Engl J Med | 1986 | 3511384 | No |
260 | 4702 | 4702.0 | 222.5 | 222.5 | Executive functions. | Adele Diamond | Annu Rev Psychol | 2013 | 23020641 | No |
261 | 9351 | 4675.5 | 208.83 | 104.4 | Parkinsonism: onset, progression and mortality. | M M Hoehn, M D Yahr | Neurology | 1967 | 6067254 | Yes |
262 | 4670 | 4670.0 | 103.05 | 103.0 | Alzheimer's disease: genes, proteins, and therapy. | D J Selkoe | Physiol Rev | 2001 | 11274343 | No |
263 | 4668 | 4668.0 | 129.87 | 129.9 | Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes. | P Matsudaira | J Biol Chem | 1987 | 3611052 | Yes |
264 | 4663 | 4663.0 | 215.3 | 215.3 | The McGill Pain Questionnaire: major properties and scoring methods. | Ronald Melzack | Pain | 1975 | 1235985 | Yes |
265 | 4662 | 4662.0 | 72.27 | 72.3 | Aggregation of blood platelets by adenosine diphosphate and its reversal. | G V Born | Nature | 1962 | 13871375 | Yes |
266 | 13952 | 4650.7 | 305.33 | 101.8 | Refinement of macromolecular structures by the maximum-likelihood method. | G N Murshudov, A A Vagin, E J Dodson | Acta Crystallogr D Biol Crystallogr | 1997 | 15299926 | Yes |
267 | 4643 | 4643.0 | 125.39 | 125.4 | A rapid banding technique for human chromosomes. | M Seabright | Lancet | 1971 | 4107917 | Yes |
268 | 27858 | 4643.0 | 982.75 | 163.8 | Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support. | Paul A Harris, Robert Taylor, Robert Thielke, Jonathon Payne, Nathaniel Gonzalez, Jose G Conde | J Biomed Inform | 2009 | 18929686 | Yes |
269 | 13922 | 4640.7 | 1381.78 | 460.6 | Cancer statistics, 2020. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2020 | 31912902 | Yes |
270 | 13907 | 4635.7 | 480.0 | 160.0 | Nitric oxide: physiology, pathophysiology, and pharmacology. | S Moncada, R M Palmer, E A Higgs | Pharmacol Rev | 1991 | 1852778 | No |
271 | 18528 | 4632.0 | 535.03 | 133.8 | MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. | Koichiro Tamura, Joel Dudley, Masatoshi Nei, Sudhir Kumar | Mol Biol Evol | 2007 | 17488738 | Yes |
272 | 4604 | 4604.0 | 102.27 | 102.3 | Prions. | S B Prusiner | Proc Natl Acad Sci U S A | 1998 | 9811807 | No |
273 | 18335 | 4583.8 | 296.34 | 74.1 | A new and rapid colorimetric determination of acetylcholinesterase activity. | G L Ellman, K D Courtney, V Andres, R M Feather-Stone | Biochem Pharmacol | 1961 | 13726518 | Yes |
274 | 4583 | 4583.0 | 40.3 | 40.3 | The Limited In Vitro Lifetime Of Human Diploid Cell Strains. | L Hayflick | Exp Cell Res | 1965 | 14315085 | Yes |
275 | 9156 | 4578.0 | 182.38 | 91.2 | Assessment of older people: self-maintaining and instrumental activities of daily living. | M P Lawton, E M Brody | Gerontologist | 1969 | 5349366 | Yes |
276 | 9091 | 4545.5 | 249.48 | 124.7 | Ab initio molecular dynamics for liquid metals. | G Kresse, J Hafner | Phys Rev B Condens Matter | 1993 | 10004490 | Yes |
277 | 9055 | 4527.5 | 310.24 | 155.1 | Qualitative content analysis in nursing research: concepts, procedures and measures to achieve trustworthiness. | U H Graneheim, B Lundman | Nurse Educ Today | 2004 | 14769454 | No |
278 | 4525 | 4525.0 | 98.01 | 98.0 | ras genes. | M Barbacid | Annu Rev Biochem | 1987 | 3304147 | No |
279 | 9048 | 4524.0 | 330.99 | 165.5 | Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models. | Kristopher J Preacher, Andrew F Hayes | Behav Res Methods | 2008 | 18697684 | Yes |
280 | 4524 | 4524.0 | 226.87 | 226.9 | Minimap2: pairwise alignment for nucleotide sequences. | Heng Li | Bioinformatics | 2018 | 29750242 | Yes |
281 | 9036 | 4518.0 | 149.87 | 74.9 | Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). | J M McCord, I Fridovich | J Biol Chem | 1969 | 5389100 | Yes |
282 | 4516 | 4516.0 | 106.2 | 106.2 | The genetical evolution of social behaviour. I. | W D Hamilton | J Theor Biol | 1964 | 5875341 | Yes |
283 | 9032 | 4516.0 | 200.96 | 100.5 | Primer3 on the WWW for general users and for biologist programmers. | S Rozen, H Skaletsky | Methods Mol Biol | 2000 | 10547847 | Yes |
284 | 4513 | 4513.0 | 93.23 | 93.2 | Alternative activation of macrophages. | Siamon Gordon | Nat Rev Immunol | 2003 | 12511873 | No |
285 | 4497 | 4497.0 | 140.77 | 140.8 | Updating P300: an integrative theory of P3a and P3b. | John Polich | Clin Neurophysiol | 2007 | 17573239 | No |
286 | 8947 | 4473.5 | 148.26 | 74.1 | Functional Evaluation: The Barthel Index. | F I Mahoney, D W Barthel | Md State Med J | 1965 | 14258950 | Yes |
287 | 8922 | 4461.0 | 0.0 | 0.0 | A simplified method of evaluating dose-effect experiments. | J T Litchfield, F Wilcoxon | J Pharmacol Exp Ther | 1949 | 18152921 | Yes |
288 | 4454 | 4454.0 | 90.14 | 90.1 | Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. | M Kozak | Cell | 1986 | 3943125 | Yes |
289 | 4446 | 4446.0 | 102.74 | 102.7 | Cancer. p53, guardian of the genome. | D P Lane | Nature | 1992 | 1614522 | No |
290 | 4446 | 4446.0 | 107.75 | 107.8 | A new method for predicting signal sequence cleavage sites. | G von Heijne | Nucleic Acids Res | 1986 | 3714490 | Yes |
291 | 13304 | 4434.7 | 528.71 | 176.2 | A global measure of perceived stress. | S Cohen, T Kamarck, R Mermelstein | J Health Soc Behav | 1983 | 6668417 | Yes |
292 | 13302 | 4434.0 | 586.08 | 195.4 | Development and validation of brief measures of positive and negative affect: the PANAS scales. | D Watson, L A Clark, A Tellegen | J Pers Soc Psychol | 1988 | 3397865 | Yes |
293 | 26603 | 4433.8 | 930.36 | 155.1 | Global cancer statistics. | Ahmedin Jemal, Freddie Bray, Melissa M Center, Jacques Ferlay, Elizabeth Ward, David Forman | CA Cancer J Clin | 2011 | 21296855 | Yes |
294 | 4432 | 4432.0 | 165.69 | 165.7 | FreeSurfer. | Bruce Fischl | Neuroimage | 2012 | 22248573 | No |
295 | 8839 | 4419.5 | 236.91 | 118.5 | A synaptic model of memory: long-term potentiation in the hippocampus. | T V Bliss, G L Collingridge | Nature | 1993 | 8421494 | No |
296 | 8830 | 4415.0 | 211.44 | 105.7 | Collective dynamics of 'small-world' networks. | D J Watts, S H Strogatz | Nature | 1998 | 9623998 | Yes |
297 | 8782 | 4391.0 | 161.07 | 80.5 | A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels. | W M Bonner, R A Laskey | Eur J Biochem | 1974 | 4850204 | Yes |
298 | 8771 | 4385.5 | 221.62 | 110.8 | Assessment of coma and impaired consciousness. A practical scale. | G Teasdale, B Jennett | Lancet | 1974 | 4136544 | Yes |
299 | 8745 | 4372.5 | 202.13 | 101.1 | SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. | N Guex, M C Peitsch | Electrophoresis | 1997 | 9504803 | Yes |
300 | 4365 | 4365.0 | 90.12 | 90.1 | Wnt/beta-catenin signaling in development and disease. | Hans Clevers | Cell | 2006 | 17081971 | No |
301 | 4359 | 4359.0 | 83.46 | 83.5 | The phosphoinositide 3-kinase pathway. | Lewis C Cantley | Science | 2002 | 12040186 | No |
302 | 4355 | 4355.0 | 218.8 | 218.8 | Tetramethyl benzidine for horseradish peroxidase neurohistochemistry: a non-carcinogenic blue reaction product with superior sensitivity for visualizing neural afferents and efferents. | M M Mesulam | J Histochem Cytochem | 1978 | 24068 | Yes |
303 | 4351 | 4351.0 | 112.22 | 112.2 | Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. | Y Nishizuka | Science | 1992 | 1411571 | No |
304 | 4350 | 4350.0 | 103.59 | 103.6 | Why most published research findings are false. | John P A Ioannidis | PLoS Med | 2005 | 16060722 | Yes |
305 | 25913 | 4318.8 | 959.65 | 159.9 | MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. | Koichiro Tamura, Daniel Peterson, Nicholas Peterson, Glen Stecher, Masatoshi Nei, Sudhir Kumar | Mol Biol Evol | 2011 | 21546353 | Yes |
306 | 12950 | 4316.7 | 653.89 | 218.0 | Cancer statistics, 2016. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2016 | 26742998 | Yes |
307 | 4315 | 4315.0 | 101.19 | 101.2 | Mechanisms of angiogenesis. | W Risau | Nature | 1997 | 9109485 | No |
308 | 4303 | 4303.0 | 128.87 | 128.9 | Glutamate neurotoxicity and diseases of the nervous system. | D W Choi | Neuron | 1988 | 2908446 | No |
309 | 8606 | 4303.0 | 116.72 | 58.4 | Preparation of iodine-131 labelled human growth hormone of high specific activity. | W M Hunter, F C Greenwood | Nature | 1962 | 14450081 | Yes |
310 | 8604 | 4302.0 | 232.28 | 116.1 | Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetii. | Daniel E Voth, Robert A Heinzen | Cell Microbiol | 2007 | 17381428 | No |
311 | 4282 | 4282.0 | 93.11 | 93.1 | Apoptosis by death factor. | S Nagata | Cell | 1997 | 9039262 | No |
312 | 4281 | 4281.0 | 113.64 | 113.6 | The molecular heterogeneity of protein kinase C and its implications for cellular regulation. | Y Nishizuka | Nature | 1988 | 3045562 | No |
313 | 4258 | 4258.0 | 110.49 | 110.5 | Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. | A H Wyllie | Nature | 1980 | 6245367 | Yes |
314 | 4258 | 4258.0 | 155.18 | 155.2 | EuroQol: the current state of play. | R Brooks | Health Policy | 1996 | 10158943 | No |
315 | 4249 | 4249.0 | 80.15 | 80.2 | The detection of disease clustering and a generalized regression approach. | N Mantel | Cancer Res | 1967 | 6018555 | Yes |
316 | 4242 | 4242.0 | 0.0 | 0.0 | Evolution in Mendelian Populations. | S Wright | Genetics | 1931 | 17246615 | Yes |
317 | 4237 | 4237.0 | 0.0 | 0.0 | Estimation of nuclear population from microtome sections. | M Abercrombie | Anat Rec | 1946 | 21015608 | Yes |
318 | 4234 | 4234.0 | 0.0 | 0.0 | The colorimetric estimation of formaldehyde by means of the Hantzsch reaction. | T Nash | Biochem J | 1953 | 13105648 | Yes |
319 | 4228 | 4228.0 | 0.0 | 0.0 | Amino acid metabolism in mammalian cell cultures. | H Eagle | Science | 1959 | 13675766 | Yes |
320 | 4220 | 4220.0 | 87.43 | 87.4 | The retinoblastoma protein and cell cycle control. | R A Weinberg | Cell | 1995 | 7736585 | No |
321 | 4217 | 4217.0 | 93.8 | 93.8 | Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing. | S Henikoff | Gene | 1984 | 6235151 | Yes |
322 | 4217 | 4217.0 | 0.0 | 0.0 | New methods for calculating metabolic rate with special reference to protein metabolism. | J B De B Weir | J Physiol | 1949 | 15394301 | Yes |
323 | 8420 | 4210.0 | 243.6 | 121.8 | Estimating F-Statistics For The Analysis Of Population Structure. | B S Weir, C Clark Cockerham | Evolution | 1984 | 28563791 | Yes |
324 | 12624 | 4208.0 | 405.31 | 135.1 | Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. | E R DeLong, D M DeLong, D L Clarke-Pearson | Biometrics | 1988 | 3203132 | Yes |
325 | 12621 | 4207.0 | 789.21 | 263.1 | Cancer statistics, 2018. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2018 | 29313949 | Yes |
326 | 4200 | 4200.0 | 0.0 | 0.0 | A relation between non-esterified fatty acids in plasma and the metabolism of glucose. | V P Dole | J Clin Invest | 1956 | 13286333 | Yes |
327 | 8389 | 4194.5 | 310.67 | 155.3 | The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay. | I F Benzie, J J Strain | Anal Biochem | 1996 | 8660627 | Yes |
328 | 8378 | 4189.0 | 347.04 | 173.5 | The timed "Up & Go": a test of basic functional mobility for frail elderly persons. | D Podsiadlo, S Richardson | J Am Geriatr Soc | 1991 | 1991946 | Yes |
329 | 4181 | 4181.0 | 75.68 | 75.7 | Generalized lacZ expression with the ROSA26 Cre reporter strain. | P Soriano | Nat Genet | 1999 | 9916792 | Yes |
330 | 4180 | 4180.0 | 90.97 | 91.0 | Atherosclerosis. | A J Lusis | Nature | 2000 | 11001066 | No |
331 | 12538 | 4179.3 | 463.32 | 154.4 | HTSeq--a Python framework to work with high-throughput sequencing data. | Simon Anders, Paul Theodor Pyl, Wolfgang Huber | Bioinformatics | 2015 | 25260700 | Yes |
332 | 4179 | 4179.0 | 87.13 | 87.1 | Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. | C J Marshall | Cell | 1995 | 7834738 | No |
333 | 4155 | 4155.0 | 155.97 | 156.0 | Measuring the accuracy of diagnostic systems. | J A Swets | Science | 1988 | 3287615 | No |
334 | 24930 | 4155.0 | 813.45 | 135.6 | Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. | D R Matthews, J P Hosker, A S Rudenski, B A Naylor, D F Treacher, R C Turner | Diabetologia | 1985 | 3899825 | Yes |
335 | 4155 | 4155.0 | 88.85 | 88.8 | Protein production by auto-induction in high density shaking cultures. | F William Studier | Protein Expr Purif | 2005 | 15915565 | Yes |
336 | 4152 | 4152.0 | 50.46 | 50.5 | Bone: formation by autoinduction. | M R Urist | Science | 1965 | 5319761 | Yes |
337 | 8302 | 4151.0 | 0.0 | 0.0 | Radiological assessment of osteo-arthrosis. | J H Kellgren, J S Lawrence | Ann Rheum Dis | 1957 | 13498604 | Yes |
338 | 8292 | 4146.0 | 347.69 | 173.8 | phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data. | Paul J McMurdie, Susan Holmes | PLoS One | 2013 | 23630581 | Yes |
339 | 4143 | 4143.0 | 166.9 | 166.9 | Determination of protein: a modification of the Lowry method that gives a linear photometric response. | E F Hartree | Anal Biochem | 1972 | 4115981 | Yes |
340 | 8279 | 4139.5 | 177.55 | 88.8 | Genomic sequencing. | G M Church, W Gilbert | Proc Natl Acad Sci U S A | 1984 | 6326095 | Yes |
341 | 4136 | 4136.0 | 0.0 | 0.0 | The determination of enzyme inhibitor constants. | M Dixon | Biochem J | 1953 | 13093635 | Yes |
342 | 12368 | 4122.7 | 552.1 | 184.0 | Deep learning. | Yann LeCun, Yoshua Bengio, Geoffrey Hinton | Nature | 2015 | 26017442 | No |
343 | 4117 | 4117.0 | 91.44 | 91.4 | PAML: a program package for phylogenetic analysis by maximum likelihood. | Z Yang | Comput Appl Biosci | 1997 | 9367129 | Yes |
344 | 4115 | 4115.0 | 107.52 | 107.5 | Staphylococcus aureus infections. | F D Lowy | N Engl J Med | 1998 | 9709046 | No |
345 | 4094 | 4094.0 | 110.59 | 110.6 | Mesenchymal stem cells. | A I Caplan | J Orthop Res | 1991 | 1870029 | Yes |
346 | 4082 | 4082.0 | 127.73 | 127.7 | Bacterial evolution. | C R Woese | Microbiol Rev | 1987 | 2439888 | No |
347 | 12241 | 4080.3 | 453.33 | 151.1 | A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. | J Ware, M Kosinski, S D Keller | Med Care | 1996 | 8628042 | Yes |
348 | 16207 | 4051.8 | 518.55 | 129.6 | A consistent and accurate ab initio parametrization of density functional dispersion correction (DFT-D) for the 94 elements H-Pu. | Stefan Grimme, Jens Antony, Stephan Ehrlich, Helge Krieg | J Chem Phys | 2010 | 20423165 | Yes |
349 | 8095 | 4047.5 | 209.82 | 104.9 | Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. | D E Paglia, W N Valentine | J Lab Clin Med | 1967 | 6066618 | Yes |
350 | 16180 | 4045.0 | 611.26 | 152.8 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | Ann Intern Med | 2009 | 19622511 | No |
351 | 8081 | 4040.5 | 259.92 | 130.0 | DnaSP v5: a software for comprehensive analysis of DNA polymorphism data. | P Librado, J Rozas | Bioinformatics | 2009 | 19346325 | Yes |
352 | 4036 | 4036.0 | 83.94 | 83.9 | The green fluorescent protein. | R Y Tsien | Annu Rev Biochem | 1998 | 9759496 | No |
353 | 28187 | 4026.7 | 623.24 | 89.0 | UCSF Chimera--a visualization system for exploratory research and analysis. | Eric F Pettersen, Thomas D Goddard, Conrad C Huang, Gregory S Couch, Daniel M Greenblatt, Elaine C Meng, Thomas E Ferrin | J Comput Chem | 2004 | 15264254 | Yes |
354 | 4026 | 4026.0 | 175.69 | 175.7 | A short portable mental status questionnaire for the assessment of organic brain deficit in elderly patients. | E Pfeiffer | J Am Geriatr Soc | 1975 | 1159263 | Yes |
355 | 4016 | 4016.0 | 103.64 | 103.6 | Integrins: a family of cell surface receptors. | R O Hynes | Cell | 1987 | 3028640 | No |
356 | 12016 | 4005.3 | 650.79 | 216.9 | Cancer Statistics, 2017. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2017 | 28055103 | Yes |
357 | 3997 | 3997.0 | 101.52 | 101.5 | The Scree Test For The Number Of Factors. | R B Cattell | Multivariate Behav Res | 1966 | 26828106 | Yes |
358 | 7965 | 3982.5 | 203.64 | 101.8 | tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence. | T M Lowe, S R Eddy | Nucleic Acids Res | 1997 | 9023104 | Yes |
359 | 3982 | 3982.0 | 106.82 | 106.8 | What is the evidence that tumors are angiogenesis dependent? | J Folkman | J Natl Cancer Inst | 1990 | 1688381 | No |
360 | 3980 | 3980.0 | 78.56 | 78.6 | Hypoxia--a key regulatory factor in tumour growth. | Adrian L Harris | Nat Rev Cancer | 2002 | 11902584 | No |
361 | 3978 | 3978.0 | 128.18 | 128.2 | Tissue destruction by neutrophils. | S J Weiss | N Engl J Med | 1989 | 2536474 | No |
362 | 3968 | 3968.0 | 0.0 | 0.0 | Staining of tissue sections for electron microscopy with heavy metals. | M L Watson | J Biophys Biochem Cytol | 1958 | 13563554 | Yes |
363 | 3964 | 3964.0 | 115.68 | 115.7 | Soft self-consistent pseudopotentials in a generalized eigenvalue formalism. | D Vanderbilt | Phys Rev B Condens Matter | 1990 | 9993096 | Yes |
364 | 3956 | 3956.0 | 125.96 | 126.0 | How do you feel--now? The anterior insula and human awareness. | A D Bud Craig | Nat Rev Neurosci | 2009 | 19096369 | No |
365 | 3954 | 3954.0 | 70.04 | 70.0 | Principles that govern the folding of protein chains. | C B Anfinsen | Science | 1973 | 4124164 | Yes |
366 | 3952 | 3952.0 | 146.3 | 146.3 | A concordance correlation coefficient to evaluate reproducibility. | L I Lin | Biometrics | 1989 | 2720055 | Yes |
367 | 3949 | 3949.0 | 129.52 | 129.5 | Weighted kappa: nominal scale agreement with provision for scaled disagreement or partial credit. | J Cohen | Psychol Bull | 1968 | 19673146 | Yes |
368 | 15739 | 3934.8 | 578.22 | 144.6 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | BMJ | 2009 | 19622551 | No |
369 | 3934 | 3934.0 | 144.04 | 144.0 | Disc Electrophoresis. I. Background And Theory. | L Ornstein | Ann N Y Acad Sci | 1964 | 14240533 | Yes |
370 | 7865 | 3932.5 | 148.04 | 74.0 | A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. | R S Sikorski, P Hieter | Genetics | 1989 | 2659436 | Yes |
371 | 7854 | 3927.0 | 212.29 | 106.1 | Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose. | H Aviv, P Leder | Proc Natl Acad Sci U S A | 1972 | 4504350 | Yes |
372 | 3926 | 3926.0 | 96.7 | 96.7 | Multiple sequence alignment with hierarchical clustering. | F Corpet | Nucleic Acids Res | 1988 | 2849754 | Yes |
373 | 3922 | 3922.0 | 122.36 | 122.4 | Emerging adulthood. A theory of development from the late teens through the twenties. | J J Arnett | Am Psychol | 2000 | 10842426 | Yes |
374 | 3901 | 3901.0 | 120.26 | 120.3 | Nitric oxide as a secretory product of mammalian cells. | C Nathan | FASEB J | 1992 | 1381691 | No |
375 | 7784 | 3892.0 | 293.85 | 146.9 | Multiwfn: a multifunctional wavefunction analyzer. | Tian Lu, Feiwu Chen | J Comput Chem | 2012 | 22162017 | Yes |
376 | 11672 | 3890.7 | 304.58 | 101.5 | Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. | J F Kerr, A H Wyllie, A R Currie | Br J Cancer | 1972 | 4561027 | No |
377 | 11670 | 3890.0 | 298.57 | 99.5 | Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. | W H Habig, M J Pabst, W B Jakoby | J Biol Chem | 1974 | 4436300 | Yes |
378 | 3883 | 3883.0 | 98.52 | 98.5 | Oxidative stress, antioxidants and stress tolerance. | Ron Mittler | Trends Plant Sci | 2002 | 12234732 | No |
379 | 7758 | 3879.0 | 197.46 | 98.7 | Control of goal-directed and stimulus-driven attention in the brain. | Maurizio Corbetta, Gordon L Shulman | Nat Rev Neurosci | 2002 | 11994752 | No |
380 | 3872 | 3872.0 | 119.13 | 119.1 | Pharmacological implications of microsomal enzyme induction. | A H Conney | Pharmacol Rev | 1967 | 4383307 | Yes |
381 | 3872 | 3872.0 | 80.19 | 80.2 | Protein secondary structure prediction based on position-specific scoring matrices. | D T Jones | J Mol Biol | 1999 | 10493868 | Yes |
382 | 3870 | 3870.0 | 125.27 | 125.3 | Preparation of isolated rat liver cells. | P O Seglen | Methods Cell Biol | 1976 | 177845 | No |
383 | 3861 | 3861.0 | 83.8 | 83.8 | Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. | Rakesh K Jain | Science | 2005 | 15637262 | No |
384 | 7721 | 3860.5 | 215.1 | 107.5 | Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. | S Duval, R Tweedie | Biometrics | 2000 | 10877304 | Yes |
385 | 3851 | 3851.0 | 185.99 | 186.0 | Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs. | Daniël Lakens | Front Psychol | 2013 | 24324449 | No |
386 | 3850 | 3850.0 | 127.99 | 128.0 | Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD. | Russell A Barkley | Psychol Bull | 1997 | 9000892 | No |
387 | 3848 | 3848.0 | 102.66 | 102.7 | Propensity score methods for bias reduction in the comparison of a treatment to a non-randomized control group. | R B D'Agostino | Stat Med | 1998 | 9802183 | Yes |
388 | 3838 | 3838.0 | 101.88 | 101.9 | Observational study of behavior: sampling methods. | J Altmann | Behaviour | 1974 | 4597405 | No |
389 | 7656 | 3828.0 | 144.59 | 72.3 | Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. | A H Brand, N Perrimon | Development | 1993 | 8223268 | Yes |
390 | 3818 | 3818.0 | 90.97 | 91.0 | Caspases: the executioners of apoptosis. | G M Cohen | Biochem J | 1997 | 9337844 | No |
391 | 3818 | 3818.0 | 83.7 | 83.7 | Folding DNA to create nanoscale shapes and patterns. | Paul W K Rothemund | Nature | 2006 | 16541064 | Yes |
392 | 34334 | 3814.9 | 874.84 | 97.2 | The Sequence Alignment/Map format and SAMtools. | Heng Li, Bob Handsaker, Alec Wysoker, Tim Fennell, Jue Ruan, Nils Homer, Gabor Marth, Goncalo Abecasis, Richard Durbin | Bioinformatics | 2009 | 19505943 | Yes |
393 | 3808 | 3808.0 | 102.74 | 102.7 | Revisions in the International System for Staging Lung Cancer. | C F Mountain | Chest | 1997 | 9187198 | Yes |
394 | 15225 | 3806.2 | 461.85 | 115.5 | clusterProfiler: an R package for comparing biological themes among gene clusters. | Guangchuang Yu, Li-Gen Wang, Yanyan Han, Qing-Yu He | OMICS | 2012 | 22455463 | Yes |
395 | 11412 | 3804.0 | 381.54 | 127.2 | featureCounts: an efficient general purpose program for assigning sequence reads to genomic features. | Yang Liao, Gordon K Smyth, Wei Shi | Bioinformatics | 2014 | 24227677 | Yes |
396 | 3795 | 3795.0 | 97.94 | 97.9 | Sequencing technologies - the next generation. | Michael L Metzker | Nat Rev Genet | 2010 | 19997069 | No |
397 | 3791 | 3791.0 | 80.12 | 80.1 | A catalogue of splice junction sequences. | S M Mount | Nucleic Acids Res | 1982 | 7063411 | Yes |
398 | 3784 | 3784.0 | 96.94 | 96.9 | Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? | Kim A Brogden | Nat Rev Microbiol | 2005 | 15703760 | No |
399 | 3777 | 3777.0 | 84.16 | 84.2 | Instability and decay of the primary structure of DNA. | T Lindahl | Nature | 1993 | 8469282 | No |
400 | 7552 | 3776.0 | 182.48 | 91.2 | Mitochondria and apoptosis. | D R Green, J C Reed | Science | 1998 | 9721092 | No |
401 | 3773 | 3773.0 | 73.84 | 73.8 | Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. | G R Martin | Proc Natl Acad Sci U S A | 1981 | 6950406 | Yes |
402 | 3772 | 3772.0 | 77.6 | 77.6 | TGF-beta signal transduction. | J Massagué | Annu Rev Biochem | 1998 | 9759503 | No |
403 | 3761 | 3761.0 | 146.54 | 146.5 | Estimation of the molecular weights of proteins by Sephadex gel-filtration. | P Andrews | Biochem J | 1964 | 4158310 | Yes |
404 | 3754 | 3754.0 | 107.21 | 107.2 | Silver stain for proteins in polyacrylamide gels: a modified procedure with enhanced uniform sensitivity. | J H Morrissey | Anal Biochem | 1981 | 6172996 | Yes |
405 | 3754 | 3754.0 | 94.4 | 94.4 | The origins and the future of microfluidics. | George M Whitesides | Nature | 2006 | 16871203 | No |
406 | 11223 | 3741.0 | 215.39 | 71.8 | Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. | J D Dignam, R M Lebovitz, R G Roeder | Nucleic Acids Res | 1983 | 6828386 | Yes |
407 | 3741 | 3741.0 | 88.98 | 89.0 | Free R value: a novel statistical quantity for assessing the accuracy of crystal structures. | A T Brünger | Nature | 1992 | 18481394 | Yes |
408 | 14960 | 3740.0 | 352.53 | 88.1 | Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. | Ben Langmead, Cole Trapnell, Mihai Pop, Steven L Salzberg | Genome Biol | 2009 | 19261174 | Yes |
409 | 3735 | 3735.0 | 100.62 | 100.6 | Drug combination studies and their synergy quantification using the Chou-Talalay method. | Ting-Chao Chou | Cancer Res | 2010 | 20068163 | Yes |
410 | 3732 | 3732.0 | 79.78 | 79.8 | Scaling and assessment of data quality. | Philip Evans | Acta Crystallogr D Biol Crystallogr | 2006 | 16369096 | No |
411 | 3731 | 3731.0 | 86.54 | 86.5 | Novel proteinaceous infectious particles cause scrapie. | S B Prusiner | Science | 1982 | 6801762 | Yes |
412 | 3728 | 3728.0 | 107.81 | 107.8 | What's wrong with Bonferroni adjustments. | T V Perneger | BMJ | 1998 | 9553006 | No |
413 | 3721 | 3721.0 | 107.17 | 107.2 | Functions of DNA methylation: islands, start sites, gene bodies and beyond. | Peter A Jones | Nat Rev Genet | 2012 | 22641018 | No |
414 | 14860 | 3715.0 | 384.63 | 96.2 | Global cancer statistics, 2002. | D Max Parkin, Freddie Bray, J Ferlay, Paola Pisani | CA Cancer J Clin | 2005 | 15761078 | Yes |
415 | 3712 | 3712.0 | 117.48 | 117.5 | genepop'007: a complete re-implementation of the genepop software for Windows and Linux. | François Rousset | Mol Ecol Resour | 2008 | 21585727 | Yes |
416 | 7420 | 3710.0 | 207.76 | 103.9 | BEAST: Bayesian evolutionary analysis by sampling trees. | Alexei J Drummond, Andrew Rambaut | BMC Evol Biol | 2007 | 17996036 | Yes |
417 | 3705 | 3705.0 | 61.49 | 61.5 | A membrane-filter technique for the detection of complementary DNA. | D T Denhardt | Biochem Biophys Res Commun | 1966 | 5963888 | Yes |
418 | 3698 | 3698.0 | 91.98 | 92.0 | Origin and physiological roles of inflammation. | Ruslan Medzhitov | Nature | 2008 | 18650913 | No |
419 | 3697 | 3697.0 | 66.94 | 66.9 | Somatic generation of antibody diversity. | S Tonegawa | Nature | 1983 | 6300689 | No |
420 | 3694 | 3694.0 | 167.24 | 167.2 | Basic principles of ROC analysis. | C E Metz | Semin Nucl Med | 1978 | 112681 | Yes |
421 | 3684 | 3684.0 | 125.64 | 125.6 | Generalized expectancies for internal versus external control of reinforcement. | J B Rotter | Psychol Monogr | 1966 | 5340840 | No |
422 | 7345 | 3672.5 | 182.99 | 91.5 | Fast and accurate long-read alignment with Burrows-Wheeler transform. | Heng Li, Richard Durbin | Bioinformatics | 2010 | 20080505 | Yes |
423 | 7338 | 3669.0 | 161.84 | 80.9 | Functional rafts in cell membranes. | K Simons, E Ikonen | Nature | 1997 | 9177342 | No |
424 | 7314 | 3657.0 | 186.3 | 93.2 | The basics of epithelial-mesenchymal transition. | Raghu Kalluri, Robert A Weinberg | J Clin Invest | 2009 | 19487818 | No |
425 | 10951 | 3650.3 | 425.54 | 141.8 | HISAT: a fast spliced aligner with low memory requirements. | Daehwan Kim, Ben Langmead, Steven L Salzberg | Nat Methods | 2015 | 25751142 | Yes |
426 | 3647 | 3647.0 | 105.47 | 105.5 | Protective and damaging effects of stress mediators. | B S McEwen | N Engl J Med | 1998 | 9428819 | No |
427 | 3646 | 3646.0 | 100.95 | 101.0 | Biological roles of oligosaccharides: all of the theories are correct. | A Varki | Glycobiology | 1993 | 8490246 | No |
428 | 3632 | 3632.0 | 88.68 | 88.7 | I-TASSER server for protein 3D structure prediction. | Yang Zhang | BMC Bioinformatics | 2008 | 18215316 | Yes |
429 | 18158 | 3631.6 | 698.26 | 139.7 | The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. | D J Buysse, C F Reynolds, T H Monk, S R Berman, D J Kupfer | Psychiatry Res | 1989 | 2748771 | Yes |
430 | 7261 | 3630.5 | 161.73 | 80.9 | Inference of macromolecular assemblies from crystalline state. | Evgeny Krissinel, Kim Henrick | J Mol Biol | 2007 | 17681537 | Yes |
431 | 7250 | 3625.0 | 183.87 | 91.9 | The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique. | R C Graham, M J Karnovsky | J Histochem Cytochem | 1966 | 5962951 | Yes |
432 | 3625 | 3625.0 | 103.27 | 103.3 | Graphene: status and prospects. | A K Geim | Science | 2009 | 19541989 | Yes |
433 | 3619 | 3619.0 | 108.62 | 108.6 | Inositol trisphosphate and diacylglycerol as second messengers. | M J Berridge | Biochem J | 1984 | 6146314 | No |
434 | 7236 | 3618.0 | 245.53 | 122.8 | FLASH: fast length adjustment of short reads to improve genome assemblies. | Tanja Magoč, Steven L Salzberg | Bioinformatics | 2011 | 21903629 | Yes |
435 | 7202 | 3601.0 | 180.6 | 90.3 | An integrative theory of prefrontal cortex function. | E K Miller, J D Cohen | Annu Rev Neurosci | 2001 | 11283309 | No |
436 | 3600 | 3600.0 | 101.07 | 101.1 | EEG alpha and theta oscillations reflect cognitive and memory performance: a review and analysis. | W Klimesch | Brain Res Brain Res Rev | 1999 | 10209231 | No |
437 | 7200 | 3600.0 | 173.64 | 86.8 | The plant immune system. | Jonathan D G Jones, Jeffery L Dangl | Nature | 2006 | 17108957 | No |
438 | 7195 | 3597.5 | 250.5 | 125.2 | Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. | Laurent Excoffier, Heidi E L Lischer | Mol Ecol Resour | 2010 | 21565059 | Yes |
439 | 3592 | 3592.0 | 84.55 | 84.5 | Marrow stromal cells as stem cells for nonhematopoietic tissues. | D J Prockop | Science | 1997 | 9082988 | No |
440 | 3592 | 3592.0 | 93.79 | 93.8 | The adolescent brain and age-related behavioral manifestations. | L P Spear | Neurosci Biobehav Rev | 2000 | 10817843 | No |
441 | 21514 | 3585.7 | 1006.3 | 167.7 | Global cancer statistics, 2012. | Lindsey A Torre, Freddie Bray, Rebecca L Siegel, Jacques Ferlay, Joannie Lortet-Tieulent, Ahmedin Jemal | CA Cancer J Clin | 2015 | 25651787 | Yes |
442 | 3579 | 3579.0 | 84.42 | 84.4 | Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. | Ting-Chao Chou | Pharmacol Rev | 2006 | 16968952 | No |
443 | 7110 | 3555.0 | 287.13 | 143.6 | The qualitative content analysis process. | Satu Elo, Helvi Kyngäs | J Adv Nurs | 2008 | 18352969 | Yes |
444 | 3548 | 3548.0 | 71.21 | 71.2 | Mammalian neural stem cells. | F H Gage | Science | 2000 | 10688783 | No |
445 | 7058 | 3529.0 | 355.65 | 177.8 | Microsomal lipid peroxidation. | J A Buege, S D Aust | Methods Enzymol | 1978 | 672633 | Yes |
446 | 3516 | 3516.0 | 66.92 | 66.9 | Signal transduction by the JNK group of MAP kinases. | R J Davis | Cell | 2000 | 11057897 | No |
447 | 3516 | 3516.0 | 161.01 | 161.0 | Estimation of average heterozygosity and genetic distance from a small number of individuals. | M Nei | Genetics | 1978 | 17248844 | Yes |
448 | 10545 | 3515.0 | 257.22 | 85.7 | Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. | Da Wei Huang, Brad T Sherman, Richard A Lempicki | Nucleic Acids Res | 2009 | 19033363 | Yes |
449 | 7026 | 3513.0 | 146.33 | 73.2 | A new method for sequencing DNA. | A M Maxam, W Gilbert | Proc Natl Acad Sci U S A | 1977 | 265521 | Yes |
450 | 3509 | 3509.0 | 73.45 | 73.5 | Profile hidden Markov models. | S R Eddy | Bioinformatics | 1998 | 9918945 | No |
451 | 3508 | 3508.0 | 90.8 | 90.8 | Microglia: a sensor for pathological events in the CNS. | G W Kreutzberg | Trends Neurosci | 1996 | 8843599 | No |
452 | 17520 | 3504.0 | 495.38 | 99.1 | Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. | O P Hamill, A Marty, E Neher, B Sakmann, F J Sigworth | Pflugers Arch | 1981 | 6270629 | Yes |
453 | 7002 | 3501.0 | 126.76 | 63.4 | Translating the histone code. | T Jenuwein, C D Allis | Science | 2001 | 11498575 | No |
454 | 3500 | 3500.0 | 54.28 | 54.3 | Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. | J D Rowley | Nature | 1973 | 4126434 | Yes |
455 | 3500 | 3500.0 | 79.75 | 79.8 | Nonalcoholic fatty liver disease. | Paul Angulo | N Engl J Med | 2002 | 11961152 | No |
456 | 3497 | 3497.0 | 94.41 | 94.4 | A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data. | Heng Li | Bioinformatics | 2011 | 21903627 | Yes |
457 | 3496 | 3496.0 | 59.02 | 59.0 | Statistical estimations in enzyme kinetics. | G N Wilkinson | Biochem J | 1961 | 13785321 | Yes |
458 | 3495 | 3495.0 | 104.41 | 104.4 | Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans. | L R Squire | Psychol Rev | 1992 | 1594723 | No |
459 | 3493 | 3493.0 | 54.99 | 55.0 | Spectroscopic determination of tryptophan and tyrosine in proteins. | H Edelhoch | Biochemistry | 1967 | 6049437 | Yes |
460 | 3492 | 3492.0 | 79.94 | 79.9 | Glutamate uptake. | N C Danbolt | Prog Neurobiol | 2001 | 11369436 | No |
461 | 3489 | 3489.0 | 81.33 | 81.3 | The dendritic cell system and its role in immunogenicity. | R M Steinman | Annu Rev Immunol | 1991 | 1910679 | No |
462 | 3486 | 3486.0 | 101.12 | 101.1 | Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity-score matched samples. | Peter C Austin | Stat Med | 2009 | 19757444 | Yes |
463 | 3473 | 3473.0 | 111.6 | 111.6 | Modeling valuations for EuroQol health states. | P Dolan | Med Care | 1997 | 9366889 | Yes |
464 | 3471 | 3471.0 | 85.09 | 85.1 | The heat-shock response. | S Lindquist | Annu Rev Biochem | 1986 | 2427013 | No |
465 | 3471 | 3471.0 | 51.89 | 51.9 | The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. | J F Woessner | Arch Biochem Biophys | 1961 | 13786180 | Yes |
466 | 6936 | 3468.0 | 77.54 | 38.8 | Receptive fields, binocular interaction and functional architecture in the cat's visual cortex. | D H Hubel, T N Wiesel | J Physiol | 1962 | 14449617 | Yes |
467 | 3461 | 3461.0 | 95.96 | 96.0 | Non-coding RNAs in human disease. | Manel Esteller | Nat Rev Genet | 2011 | 22094949 | No |
468 | 10376 | 3458.7 | 400.06 | 133.4 | Cancer statistics, 2013. | Rebecca Siegel, Deepa Naishadham, Ahmedin Jemal | CA Cancer J Clin | 2013 | 23335087 | Yes |
469 | 3454 | 3454.0 | 82.73 | 82.7 | Neural networks and physical systems with emergent collective computational abilities. | J J Hopfield | Proc Natl Acad Sci U S A | 1982 | 6953413 | Yes |
470 | 3450 | 3450.0 | 134.59 | 134.6 | Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. | O W Griffith | Anal Biochem | 1980 | 7416462 | Yes |
471 | 3449 | 3449.0 | 101.72 | 101.7 | Accelerated Profile HMM Searches. | Sean R Eddy | PLoS Comput Biol | 2011 | 22039361 | Yes |
472 | 6878 | 3439.0 | 162.65 | 81.3 | "A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum. | A P Feinberg, B Vogelstein | Anal Biochem | 1984 | 6329026 | Yes |
473 | 3430 | 3430.0 | 106.06 | 106.1 | Health promotion by social cognitive means. | Albert Bandura | Health Educ Behav | 2004 | 15090118 | Yes |
474 | 3428 | 3428.0 | 93.65 | 93.7 | Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. | R W Mahley | Science | 1988 | 3283935 | No |
475 | 3421 | 3421.0 | 88.19 | 88.2 | RELION: implementation of a Bayesian approach to cryo-EM structure determination. | Sjors H W Scheres | J Struct Biol | 2012 | 23000701 | Yes |
476 | 6837 | 3418.5 | 173.72 | 86.9 | TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. | T R Mosmann, R L Coffman | Annu Rev Immunol | 1989 | 2523712 | No |
477 | 3418 | 3418.0 | 84.76 | 84.8 | How do you feel? Interoception: the sense of the physiological condition of the body. | A D Craig | Nat Rev Neurosci | 2002 | 12154366 | No |
478 | 3417 | 3417.0 | 74.38 | 74.4 | Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. | H F Dvorak | N Engl J Med | 1986 | 3537791 | No |
479 | 3415 | 3415.0 | 96.31 | 96.3 | Room-Temperature Ionic Liquids. Solvents for Synthesis and Catalysis. | Thomas Welton | Chem Rev | 1999 | 11849019 | Yes |
480 | 3412 | 3412.0 | 85.37 | 85.4 | The pathobiology of diabetic complications: a unifying mechanism. | Michael Brownlee | Diabetes | 2005 | 15919781 | No |
481 | 10235 | 3411.7 | 464.69 | 154.9 | Cancer statistics, 2015. | Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal | CA Cancer J Clin | 2015 | 25559415 | Yes |
482 | 3405 | 3405.0 | 0.0 | 0.0 | The magical number seven plus or minus two: some limits on our capacity for processing information. | G A Miller | Psychol Rev | 1956 | 13310704 | Yes |
483 | 3404 | 3404.0 | 0.0 | 0.0 | Some factors in the interpretation of protein denaturation. | W Kauzmann | Adv Protein Chem | 1959 | 14404936 | Yes |
484 | 3395 | 3395.0 | 85.73 | 85.7 | Biologic basis for interleukin-1 in disease. | C A Dinarello | Blood | 1996 | 8630372 | No |
485 | 10164 | 3388.0 | 70.21 | 23.4 | The Preparation Of I-131-Labelled Human Growth Hormone Of High Specific Radioactivity. | F C Greenwood, W M Hunter, J S Glover | Biochem J | 1963 | 14097352 | Yes |
486 | 13520 | 3380.0 | 436.02 | 109.0 | A brief measure for assessing generalized anxiety disorder: the GAD-7. | Robert L Spitzer, Kurt Kroenke, Janet B W Williams, Bernd Löwe | Arch Intern Med | 2006 | 16717171 | Yes |
487 | 3375 | 3375.0 | 107.03 | 107.0 | DNA methylation age of human tissues and cell types. | Steve Horvath | Genome Biol | 2013 | 24138928 | Yes |
488 | 3367 | 3367.0 | 77.0 | 77.0 | Tolerance, danger, and the extended family. | P Matzinger | Annu Rev Immunol | 1994 | 8011301 | No |
489 | 10101 | 3367.0 | 251.87 | 84.0 | Understanding the Warburg effect: the metabolic requirements of cell proliferation. | Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson | Science | 2009 | 19460998 | No |
490 | 6733 | 3366.5 | 133.87 | 66.9 | Statistical significance for genomewide studies. | John D Storey, Robert Tibshirani | Proc Natl Acad Sci U S A | 2003 | 12883005 | Yes |
491 | 3364 | 3364.0 | 104.07 | 104.1 | Psychometric properties of the strengths and difficulties questionnaire. | R Goodman | J Am Acad Child Adolesc Psychiatry | 2001 | 11699809 | Yes |
492 | 10091 | 3363.7 | 365.98 | 122.0 | Cancer statistics, 2012. | Rebecca Siegel, Deepa Naishadham, Ahmedin Jemal | CA Cancer J Clin | 2012 | 22237781 | Yes |
493 | 6704 | 3352.0 | 170.71 | 85.4 | Long short-term memory. | S Hochreiter, J Schmidhuber | Neural Comput | 1997 | 9377276 | Yes |
494 | 3349 | 3349.0 | 68.44 | 68.4 | The scanning model for translation: an update. | M Kozak | J Cell Biol | 1989 | 2645293 | No |
495 | 6689 | 3344.5 | 184.68 | 92.3 | Velvet: algorithms for de novo short read assembly using de Bruijn graphs. | Daniel R Zerbino, Ewan Birney | Genome Res | 2008 | 18349386 | Yes |
496 | 3334 | 3334.0 | 81.53 | 81.5 | The basis of anisotropic water diffusion in the nervous system - a technical review. | Christian Beaulieu | NMR Biomed | 2002 | 12489094 | No |
497 | 3332 | 3332.0 | 68.14 | 68.1 | Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs. | M Kozak | Nucleic Acids Res | 1984 | 6694911 | Yes |
498 | 3325 | 3325.0 | 122.77 | 122.8 | You want to measure coping but your protocol's too long: consider the brief COPE. | C S Carver | Int J Behav Med | 1997 | 16250744 | Yes |
499 | 6638 | 3319.0 | 127.31 | 63.7 | The ubiquitin system. | A Hershko, A Ciechanover | Annu Rev Biochem | 1998 | 9759494 | No |
500 | 3318 | 3318.0 | 83.82 | 83.8 | Gene regulation by steroid hormones. | M Beato | Cell | 1989 | 2644044 | No |
501 | 6633 | 3316.5 | 157.07 | 78.5 | Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. | C Tuerk, L Gold | Science | 1990 | 2200121 | Yes |
502 | 6633 | 3316.5 | 142.04 | 71.0 | Angiogenesis in cancer and other diseases. | P Carmeliet, R K Jain | Nature | 2000 | 11001068 | No |
503 | 3316 | 3316.0 | 148.67 | 148.7 | The quality of care. How can it be assessed? | A Donabedian | JAMA | 1988 | 3045356 | No |
504 | 3306 | 3306.0 | 104.07 | 104.1 | Equilibrium Ultracentrifugation Of Dilute Solutions. | D A Yphantis | Biochemistry | 1964 | 14155091 | Yes |
505 | 3298 | 3298.0 | 79.94 | 79.9 | Wound healing--aiming for perfect skin regeneration. | P Martin | Science | 1997 | 9082989 | No |
506 | 13083 | 3270.8 | 302.26 | 75.6 | Improved methods for building protein models in electron density maps and the location of errors in these models. | T A Jones, J Y Zou, S W Cowan, M Kjeldgaard | Acta Crystallogr A | 1991 | 2025413 | Yes |
507 | 3268 | 3268.0 | 88.75 | 88.8 | Hay fever, hygiene, and household size. | D P Strachan | BMJ | 1989 | 2513902 | Yes |
508 | 3265 | 3265.0 | 86.99 | 87.0 | ABC transporters: from microorganisms to man. | C F Higgins | Annu Rev Cell Biol | 1992 | 1282354 | No |
509 | 6522 | 3261.0 | 204.03 | 102.0 | Human malaria parasites in continuous culture. | W Trager, J B Jensen | Science | 1976 | 781840 | Yes |
510 | 3255 | 3255.0 | 63.98 | 64.0 | The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. | Isaiah J Fidler | Nat Rev Cancer | 2003 | 12778135 | No |
511 | 3252 | 3252.0 | 93.45 | 93.5 | Inositol trisphosphate and diacylglycerol: two interacting second messengers. | M J Berridge | Annu Rev Biochem | 1987 | 3304132 | No |
512 | 3248 | 3248.0 | 60.03 | 60.0 | Cell signaling by receptor tyrosine kinases. | J Schlessinger | Cell | 2000 | 11057895 | No |
513 | 3244 | 3244.0 | 103.78 | 103.8 | No adjustments are needed for multiple comparisons. | K J Rothman | Epidemiology | 1990 | 2081237 | Yes |
514 | 3241 | 3241.0 | 66.67 | 66.7 | Alzheimer's disease is a synaptic failure. | Dennis J Selkoe | Science | 2002 | 12399581 | No |
515 | 3236 | 3236.0 | 76.2 | 76.2 | Photoelectrochemical cells. | M Grätzel | Nature | 2001 | 11713540 | Yes |
516 | 3235 | 3235.0 | 69.88 | 69.9 | Activators and target genes of Rel/NF-kappaB transcription factors. | H L Pahl | Oncogene | 1999 | 10602461 | No |
517 | 3230 | 3230.0 | 63.8 | 63.8 | STATs and gene regulation. | J E Darnell | Science | 1997 | 9287210 | No |
518 | 6444 | 3222.0 | 218.59 | 109.3 | Management of hepatocellular carcinoma: an update. | Jordi Bruix, Morris Sherman | Hepatology | 2011 | 21374666 | No |
519 | 3212 | 3212.0 | 79.4 | 79.4 | The transforming growth factor-beta family. | J Massagué | Annu Rev Cell Biol | 1990 | 2177343 | No |
520 | 16032 | 3206.4 | 1172.76 | 234.6 | MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms. | Sudhir Kumar, Glen Stecher, Michael Li, Christina Knyaz, Koichiro Tamura | Mol Biol Evol | 2018 | 29722887 | Yes |
521 | 3202 | 3202.0 | 65.61 | 65.6 | CpG-rich islands and the function of DNA methylation. | A P Bird | Nature | 1986 | 2423876 | No |
522 | 3202 | 3202.0 | 73.15 | 73.2 | Mitochondrial formation of reactive oxygen species. | Julio F Turrens | J Physiol | 2003 | 14561818 | No |
523 | 3199 | 3199.0 | 111.39 | 111.4 | Transformed up-down methods in psychoacoustics. | H Levitt | J Acoust Soc Am | 1971 | 5541744 | Yes |
524 | 3199 | 3199.0 | 95.41 | 95.4 | adegenet: a R package for the multivariate analysis of genetic markers. | Thibaut Jombart | Bioinformatics | 2008 | 18397895 | Yes |
525 | 6387 | 3193.5 | 199.58 | 99.8 | Superoxide dismutase: improved assays and an assay applicable to acrylamide gels. | C Beauchamp, I Fridovich | Anal Biochem | 1971 | 4943714 | Yes |
526 | 3190 | 3190.0 | 66.96 | 67.0 | Protein folding and misfolding. | Christopher M Dobson | Nature | 2003 | 14685248 | No |
527 | 6375 | 3187.5 | 174.48 | 87.2 | Projections of global mortality and burden of disease from 2002 to 2030. | Colin D Mathers, Dejan Loncar | PLoS Med | 2006 | 17132052 | Yes |
528 | 3182 | 3182.0 | 96.46 | 96.5 | Development of a classification system for periodontal diseases and conditions. | G C Armitage | Ann Periodontol | 1999 | 10863370 | No |
529 | 3169 | 3169.0 | 102.01 | 102.0 | Essential oils: their antibacterial properties and potential applications in foods--a review. | Sara Burt | Int J Food Microbiol | 2004 | 15246235 | No |
530 | 3153 | 3153.0 | 66.74 | 66.7 | Cardiac excitation-contraction coupling. | Donald M Bers | Nature | 2002 | 11805843 | No |
531 | 6303 | 3151.5 | 199.54 | 99.8 | Complex network measures of brain connectivity: uses and interpretations. | Mikail Rubinov, Olaf Sporns | Neuroimage | 2010 | 19819337 | Yes |
532 | 3140 | 3140.0 | 73.92 | 73.9 | WHAT IF: a molecular modeling and drug design program. | G Vriend | J Mol Graph | 1990 | 2268628 | Yes |
533 | 6280 | 3140.0 | 196.85 | 98.4 | The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. | Stephen B Edge, Carolyn C Compton | Ann Surg Oncol | 2010 | 20180029 | No |
534 | 3136 | 3136.0 | 0.0 | 0.0 | Diffusion-in-gel methods for immunological analysis. | O Ouchterlony | Prog Allergy | 1958 | 13578996 | Yes |
535 | 6263 | 3131.5 | 132.83 | 66.4 | Toll-like receptor signalling. | Shizuo Akira, Kiyoshi Takeda | Nat Rev Immunol | 2004 | 15229469 | No |
536 | 3128 | 3128.0 | 66.39 | 66.4 | Mechanisms of angiogenesis and arteriogenesis. | P Carmeliet | Nat Med | 2000 | 10742145 | No |
537 | 3119 | 3119.0 | 27.13 | 27.1 | Gene action in the X-chromosome of the mouse (Mus musculus L.). | M F Lyon | Nature | 1961 | 13764598 | Yes |
538 | 3118 | 3118.0 | 66.02 | 66.0 | Angiogenesis in health and disease. | Peter Carmeliet | Nat Med | 2003 | 12778163 | No |
539 | 3116 | 3116.0 | 96.15 | 96.2 | Expert committee recommendations regarding the prevention, assessment, and treatment of child and adolescent overweight and obesity: summary report. | Sarah E Barlow | Pediatrics | 2007 | 18055651 | Yes |
540 | 3107 | 3107.0 | 89.05 | 89.0 | Statistical tests of neutrality of mutations against population growth, hitchhiking and background selection. | Y X Fu | Genetics | 1997 | 9335623 | Yes |
541 | 9303 | 3101.0 | 313.09 | 104.4 | Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. | R M Palmer, A G Ferrige, S Moncada | Nature | 1987 | 3495737 | Yes |
542 | 6202 | 3101.0 | 100.85 | 50.4 | Pain mechanisms: a new theory. | R Melzack, P D Wall | Science | 1965 | 5320816 | No |
543 | 6191 | 3095.5 | 150.83 | 75.4 | In vitro selection of RNA molecules that bind specific ligands. | A D Ellington, J W Szostak | Nature | 1990 | 1697402 | Yes |
544 | 3095 | 3095.0 | 119.61 | 119.6 | Half a century of research on the Stroop effect: an integrative review. | C M MacLeod | Psychol Bull | 1991 | 2034749 | No |
545 | 6190 | 3095.0 | 203.41 | 101.7 | Measuring agreement in method comparison studies. | J M Bland, D G Altman | Stat Methods Med Res | 1999 | 10501650 | No |
546 | 9270 | 3090.0 | 194.0 | 64.7 | Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. | Benjamin P Lewis, Christopher B Burge, David P Bartel | Cell | 2005 | 15652477 | Yes |
547 | 3089 | 3089.0 | 85.87 | 85.9 | Rapid isolation of antigens from cells with a staphylococcal protein A-antibody adsorbent: parameters of the interaction of antibody-antigen complexes with protein A. | S W Kessler | J Immunol | 1975 | 1102604 | Yes |
548 | 6171 | 3085.5 | 148.98 | 74.5 | Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. | Weizhong Li, Adam Godzik | Bioinformatics | 2006 | 16731699 | Yes |
549 | 12335 | 3083.8 | 469.38 | 117.3 | APACHE II: a severity of disease classification system. | W A Knaus, E A Draper, D P Wagner, J E Zimmerman | Crit Care Med | 1985 | 3928249 | Yes |
550 | 6160 | 3080.0 | 181.11 | 90.6 | Complex brain networks: graph theoretical analysis of structural and functional systems. | Ed Bullmore, Olaf Sporns | Nat Rev Neurosci | 2009 | 19190637 | No |
551 | 3079 | 3079.0 | 76.2 | 76.2 | Recent advances with liposomes as pharmaceutical carriers. | Vladimir P Torchilin | Nat Rev Drug Discov | 2005 | 15688077 | No |
552 | 6156 | 3078.0 | 155.76 | 77.9 | Voxel-based morphometry--the methods. | J Ashburner, K J Friston | Neuroimage | 2000 | 10860804 | No |
553 | 6154 | 3077.0 | 150.09 | 75.0 | Exploring the full spectrum of macrophage activation. | David M Mosser, Justin P Edwards | Nat Rev Immunol | 2008 | 19029990 | No |
554 | 3073 | 3073.0 | 54.16 | 54.2 | Automated electron microscope tomography using robust prediction of specimen movements. | David N Mastronarde | J Struct Biol | 2005 | 16182563 | Yes |
555 | 3071 | 3071.0 | 72.79 | 72.8 | Obesity as a medical problem. | P G Kopelman | Nature | 2000 | 10766250 | No |
556 | 6133 | 3066.5 | 53.41 | 26.7 | The serial cultivation of human diploid cell strains. | L Hayflick, P S Moorhead | Exp Cell Res | 1961 | 13905658 | Yes |
557 | 9190 | 3063.3 | 259.5 | 86.5 | Detecting the number of clusters of individuals using the software STRUCTURE: a simulation study. | G Evanno, S Regnaut, J Goudet | Mol Ecol | 2005 | 15969739 | Yes |
558 | 6126 | 3063.0 | 136.33 | 68.2 | MicroRNA signatures in human cancers. | George A Calin, Carlo M Croce | Nat Rev Cancer | 2006 | 17060945 | No |
559 | 3059 | 3059.0 | 108.03 | 108.0 | The Danish Civil Registration System. | Carsten Bøcker Pedersen | Scand J Public Health | 2011 | 21775345 | Yes |
560 | 3058 | 3058.0 | 89.45 | 89.5 | Hepatocellular carcinoma. | Hashem B El-Serag | N Engl J Med | 2011 | 21992124 | No |
561 | 6099 | 3049.5 | 108.23 | 54.1 | The language of covalent histone modifications. | B D Strahl, C D Allis | Nature | 2000 | 10638745 | Yes |
562 | 3045 | 3045.0 | 70.56 | 70.6 | Cadherin cell adhesion receptors as a morphogenetic regulator. | M Takeichi | Science | 1991 | 2006419 | No |
563 | 3045 | 3045.0 | 104.7 | 104.7 | The processing-speed theory of adult age differences in cognition. | T A Salthouse | Psychol Rev | 1996 | 8759042 | No |
564 | 3041 | 3041.0 | 122.9 | 122.9 | Adolescence-limited and life-course-persistent antisocial behavior: a developmental taxonomy. | T E Moffitt | Psychol Rev | 1993 | 8255953 | No |
565 | 6055 | 3027.5 | 161.91 | 81.0 | The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. | Taro Kawai, Shizuo Akira | Nat Immunol | 2010 | 20404851 | No |
566 | 6049 | 3024.5 | 187.95 | 94.0 | Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees. | K Tamura, M Nei | Mol Biol Evol | 1993 | 8336541 | Yes |
567 | 6049 | 3024.5 | 178.17 | 89.1 | Electrochemical photolysis of water at a semiconductor electrode. | A Fujishima, K Honda | Nature | 1972 | 12635268 | Yes |
568 | 3018 | 3018.0 | 108.59 | 108.6 | Quantifying test-retest reliability using the intraclass correlation coefficient and the SEM. | Joseph P Weir | J Strength Cond Res | 2005 | 15705040 | No |
569 | 3017 | 3017.0 | 76.25 | 76.2 | Cellular and molecular mechanisms of fibrosis. | T A Wynn | J Pathol | 2008 | 18161745 | No |
570 | 3015 | 3015.0 | 107.2 | 107.2 | A Rapid Permethylation Of Glycolipid, And Polysaccharide Catalyzed By Methylsulfinyl Carbanion In Dimethyl Sulfoxide. | S Hakomori | J Biochem | 1964 | 14135466 | Yes |
571 | 3012 | 3012.0 | 0.0 | 0.0 | A study of fixation for electron microscopy. | G E Palade | J Exp Med | 1952 | 14927794 | Yes |
572 | 6022 | 3011.0 | 0.0 | 0.0 | A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. | S Reitman, S Frankel | Am J Clin Pathol | 1957 | 13458125 | Yes |
573 | 6019 | 3009.5 | 180.2 | 90.1 | mTOR signaling in growth control and disease. | Mathieu Laplante, David M Sabatini | Cell | 2012 | 22500797 | No |
574 | 9027 | 3009.0 | 177.73 | 59.2 | Significance analysis of microarrays applied to the ionizing radiation response. | V G Tusher, R Tibshirani, G Chu | Proc Natl Acad Sci U S A | 2001 | 11309499 | Yes |
575 | 3005 | 3005.0 | 64.8 | 64.8 | TGFbeta in Cancer. | Joan Massagué | Cell | 2008 | 18662538 | No |
576 | 2993 | 2993.0 | 95.07 | 95.1 | An empirical correction for absorption anisotropy. | R H Blessing | Acta Crystallogr A | 1995 | 7702794 | Yes |
577 | 2988 | 2988.0 | 72.64 | 72.6 | The resurgence of platinum-based cancer chemotherapy. | Lloyd Kelland | Nat Rev Cancer | 2007 | 17625587 | No |
578 | 2983 | 2983.0 | 101.99 | 102.0 | Measurement of pain. | E C Huskisson | Lancet | 1974 | 4139420 | Yes |
579 | 11922 | 2980.5 | 282.64 | 70.7 | Haploview: analysis and visualization of LD and haplotype maps. | J C Barrett, B Fry, J Maller, M J Daly | Bioinformatics | 2005 | 15297300 | Yes |
580 | 2980 | 2980.0 | 55.92 | 55.9 | Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and lamm equation modeling. | P Schuck | Biophys J | 2000 | 10692345 | Yes |
581 | 2979 | 2979.0 | 0.0 | 0.0 | Catheter replacement of the needle in percutaneous arteriography; a new technique. | S I Seldinger | Acta radiol | 1953 | 13057644 | Yes |
582 | 2978 | 2978.0 | 52.78 | 52.8 | The gel-filtration behaviour of proteins related to their molecular weights over a wide range. | P Andrews | Biochem J | 1965 | 5862401 | Yes |
583 | 2978 | 2978.0 | 69.04 | 69.0 | Chemokines--chemotactic cytokines that mediate inflammation. | A D Luster | N Engl J Med | 1998 | 9459648 | No |
584 | 5955 | 2977.5 | 252.72 | 126.4 | Assessment of outcome after severe brain damage. | B Jennett, M Bond | Lancet | 1975 | 46957 | Yes |
585 | 5952 | 2976.0 | 141.15 | 70.6 | Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. | T C Chou, P Talalay | Adv Enzyme Regul | 1984 | 6382953 | Yes |
586 | 5948 | 2974.0 | 125.43 | 62.7 | Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. | D B Smith, K S Johnson | Gene | 1988 | 3047011 | Yes |
587 | 2968 | 2968.0 | 134.52 | 134.5 | The short-form McGill Pain Questionnaire. | Ronald Melzack | Pain | 1987 | 3670870 | Yes |
588 | 5935 | 2967.5 | 134.23 | 67.1 | Oxidants, oxidative stress and the biology of ageing. | T Finkel, N J Holbrook | Nature | 2000 | 11089981 | No |
589 | 23733 | 2966.6 | 516.64 | 64.6 | The Protein Data Bank. | H M Berman, J Westbrook, Z Feng, G Gilliland, T N Bhat, H Weissig, I N Shindyalov, P E Bourne | Nucleic Acids Res | 2000 | 10592235 | Yes |
590 | 2963 | 2963.0 | 58.61 | 58.6 | Toll-like receptors and innate immunity. | R Medzhitov | Nat Rev Immunol | 2001 | 11905821 | No |
591 | 8881 | 2960.3 | 207.07 | 69.0 | TopHat: discovering splice junctions with RNA-Seq. | Cole Trapnell, Lior Pachter, Steven L Salzberg | Bioinformatics | 2009 | 19289445 | Yes |
592 | 2960 | 2960.0 | 78.39 | 78.4 | Accurate Coulomb-fitting basis sets for H to Rn. | Florian Weigend | Phys Chem Chem Phys | 2006 | 16633586 | Yes |
593 | 2952 | 2952.0 | 90.81 | 90.8 | Matrix metalloproteinases and their inhibitors in connective tissue remodeling. | J F Woessner | FASEB J | 1991 | 1850705 | No |
594 | 2951 | 2951.0 | 54.79 | 54.8 | RNA interference. | Gregory J Hannon | Nature | 2002 | 12110901 | No |
595 | 26541 | 2949.0 | 571.35 | 63.5 | Cytoscape: a software environment for integrated models of biomolecular interaction networks. | Paul Shannon, Andrew Markiel, Owen Ozier, Nitin S Baliga, Jonathan T Wang, Daniel Ramage, Nada Amin, Benno Schwikowski, Trey Ideker | Genome Res | 2003 | 14597658 | Yes |
596 | 2949 | 2949.0 | 101.41 | 101.4 | What is value in health care? | Michael E Porter | N Engl J Med | 2010 | 21142528 | Yes |
597 | 8842 | 2947.3 | 242.46 | 80.8 | Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. | Y Gavrieli, Y Sherman, S A Ben-Sasson | J Cell Biol | 1992 | 1400587 | Yes |
598 | 5877 | 2938.5 | 184.74 | 92.4 | Tissue engineering. | R Langer, J P Vacanti | Science | 1993 | 8493529 | No |
599 | 2937 | 2937.0 | 80.04 | 80.0 | The nuclear factor NF-kappaB pathway in inflammation. | Toby Lawrence | Cold Spring Harb Perspect Biol | 2009 | 20457564 | No |
600 | 5870 | 2935.0 | 124.65 | 62.3 | Emergence of scaling in random networks | A L Barabasi, R Albert | Science | 1999 | 10521342 | Yes |
601 | 2932 | 2932.0 | 73.07 | 73.1 | Optimal two-stage designs for phase II clinical trials. | R Simon | Control Clin Trials | 1989 | 2702835 | Yes |
602 | 8760 | 2920.0 | 286.11 | 95.4 | Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. | R A Deyo, D C Cherkin, M A Ciol | J Clin Epidemiol | 1992 | 1607900 | Yes |
603 | 5810 | 2905.0 | 162.78 | 81.4 | Inositol trisphosphate, a novel second messenger in cellular signal transduction. | M J Berridge, R F Irvine | Nature | 1984 | 6095092 | No |
604 | 5809 | 2904.5 | 173.62 | 86.8 | The fluid mosaic model of the structure of cell membranes. | S J Singer, G L Nicolson | Science | 1972 | 4333397 | Yes |
605 | 8705 | 2901.7 | 215.07 | 71.7 | ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. | Kai Wang, Mingyao Li, Hakon Hakonarson | Nucleic Acids Res | 2010 | 20601685 | Yes |
606 | 2901 | 2901.0 | 88.34 | 88.3 | Estimation of metabolite concentrations from localized in vivo proton NMR spectra. | S W Provencher | Magn Reson Med | 1993 | 8139448 | Yes |
607 | 2897 | 2897.0 | 60.17 | 60.2 | Principles of CDK regulation. | D O Morgan | Nature | 1995 | 7877684 | No |
608 | 2894 | 2894.0 | 0.0 | 0.0 | The genetical structure of populations. | S Wright | Ann Eugen | 1951 | 24540312 | Yes |
609 | 8681 | 2893.7 | 0.0 | 0.0 | The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. | R J Havel, H A Eder, J H Bragdon | J Clin Invest | 1955 | 13252080 | Yes |
610 | 2891 | 2891.0 | 65.32 | 65.3 | Autophagy: process and function. | Noboru Mizushima | Genes Dev | 2007 | 18006683 | No |
611 | 11558 | 2889.5 | 423.9 | 106.0 | Statistical power analyses using G*Power 3.1: tests for correlation and regression analyses. | Franz Faul, Edgar Erdfelder, Axel Buchner, Albert-Georg Lang | Behav Res Methods | 2009 | 19897823 | Yes |
612 | 2889 | 2889.0 | 70.25 | 70.2 | Phase separation of integral membrane proteins in Triton X-114 solution. | C Bordier | J Biol Chem | 1981 | 6257680 | Yes |
613 | 5765 | 2882.5 | 251.81 | 125.9 | GenAlEx 6.5: genetic analysis in Excel. Population genetic software for teaching and research--an update. | Rod Peakall, Peter E Smouse | Bioinformatics | 2012 | 22820204 | Yes |
614 | 2882 | 2882.0 | 86.46 | 86.5 | Implications of normal brain development for the pathogenesis of schizophrenia. | D R Weinberger | Arch Gen Psychiatry | 1987 | 3606332 | Yes |
615 | 8643 | 2881.0 | 164.06 | 54.7 | Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. | Ron Edgar, Michael Domrachev, Alex E Lash | Nucleic Acids Res | 2002 | 11752295 | Yes |
616 | 2878 | 2878.0 | 68.49 | 68.5 | Structure and function of telomeres. | E H Blackburn | Nature | 1991 | 1708110 | No |
617 | 8634 | 2878.0 | 198.3 | 66.1 | The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. | R C Lee, R L Feinbaum, V Ambros | Cell | 1993 | 8252621 | Yes |
618 | 2875 | 2875.0 | 51.23 | 51.2 | One-step gene disruption in yeast. | R J Rothstein | Methods Enzymol | 1983 | 6310324 | Yes |
619 | 2874 | 2874.0 | 83.23 | 83.2 | Efficient methods to compute genomic predictions. | P M VanRaden | J Dairy Sci | 2008 | 18946147 | Yes |
620 | 2871 | 2871.0 | 61.89 | 61.9 | Inflammatory bowel disease. | Daniel K Podolsky | N Engl J Med | 2002 | 12167685 | No |
621 | 5737 | 2868.5 | 126.87 | 63.4 | Oncomirs - microRNAs with a role in cancer. | Aurora Esquela-Kerscher, Frank J Slack | Nat Rev Cancer | 2006 | 16557279 | No |
622 | 2868 | 2868.0 | 95.62 | 95.6 | Role of oxidative stress in development of complications in diabetes. | J W Baynes | Diabetes | 1991 | 2010041 | No |
623 | 2868 | 2868.0 | 43.53 | 43.5 | Towards a network theory of the immune system. | N K Jerne | Ann Immunol (Paris) | 1974 | 4142565 | No |
624 | 2868 | 2868.0 | 100.13 | 100.1 | Measures of reliability in sports medicine and science. | W G Hopkins | Sports Med | 2000 | 10907753 | Yes |
625 | 2867 | 2867.0 | 29.34 | 29.3 | Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism. | P Mitchell | Nature | 1961 | 13771349 | Yes |
626 | 2863 | 2863.0 | 50.48 | 50.5 | A Generalized Wilcoxon Test For Comparing Arbitrarily Singly-Censored Samples. | E A Gehan | Biometrika | 1965 | 14341275 | Yes |
627 | 2860 | 2860.0 | 0.0 | 0.0 | Phosphorus compounds in animal tissues; extraction and estimation of desoxypentose nucleic acid and of pentose nucleic acid. | W C Schneider | J Biol Chem | 1945 | 21005736 | Yes |
628 | 5714 | 2857.0 | 120.04 | 60.0 | Inflammation and cancer: back to Virchow? | F Balkwill, A Mantovani | Lancet | 2001 | 11229684 | No |
629 | 2857 | 2857.0 | 0.0 | 0.0 | A study of the adrenotropic receptors. | R P Ahlquist | Am J Physiol | 1948 | 18882199 | Yes |
630 | 2856 | 2856.0 | 52.62 | 52.6 | Genome maintenance mechanisms for preventing cancer. | J H Hoeijmakers | Nature | 2001 | 11357144 | No |
631 | 5705 | 2852.5 | 180.92 | 90.5 | Self-determination theory and the facilitation of intrinsic motivation, social development, and well-being. | R M Ryan, E L Deci | Am Psychol | 2000 | 11392867 | Yes |
632 | 8552 | 2850.7 | 255.77 | 85.3 | Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane. | G Fairbanks, T L Steck, D F Wallach | Biochemistry | 1971 | 4326772 | Yes |
633 | 5695 | 2847.5 | 145.07 | 72.5 | Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain. | J Glowinski, L L Iversen | J Neurochem | 1966 | 5950056 | Yes |
634 | 2846 | 2846.0 | 67.17 | 67.2 | MapChart: software for the graphical presentation of linkage maps and QTLs. | R E Voorrips | J Hered | 2002 | 12011185 | Yes |
635 | 2841 | 2841.0 | 46.51 | 46.5 | A Rationale And Test For The Number Of Factors In Factor Analysis. | J L Horn | Psychometrika | 1965 | 14306381 | Yes |
636 | 2840 | 2840.0 | 93.5 | 93.5 | Some studies of the protein-binding of steroids and their application to the routine micro and ultramicro measurement of various steroids in body fluids by competitive protein-binding radioassay. | B E Murphy | J Clin Endocrinol Metab | 1967 | 4291524 | Yes |
637 | 5680 | 2840.0 | 247.05 | 123.5 | Revised methods for the Salmonella mutagenicity test. | D M Maron, B N Ames | Mutat Res | 1983 | 6341825 | Yes |
638 | 2840 | 2840.0 | 0.0 | 0.0 | Notes on sugar determination. | M Smogyi | J Biol Chem | 1952 | 14938350 | Yes |
639 | 5671 | 2835.5 | 149.16 | 74.6 | Pattern recognition receptors and inflammation. | Osamu Takeuchi, Shizuo Akira | Cell | 2010 | 20303872 | No |
640 | 2833 | 2833.0 | 54.74 | 54.7 | A gene complex controlling segmentation in Drosophila. | E B Lewis | Nature | 1978 | 103000 | Yes |
641 | 2829 | 2829.0 | 64.25 | 64.2 | Calcium signaling. | David E Clapham | Cell | 2007 | 18083096 | No |
642 | 5636 | 2818.0 | 149.23 | 74.6 | Unified segmentation. | John Ashburner, Karl J Friston | Neuroimage | 2005 | 15955494 | Yes |
643 | 11271 | 2817.8 | 333.04 | 83.3 | Naive Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy. | Qiong Wang, George M Garrity, James M Tiedje, James R Cole | Appl Environ Microbiol | 2007 | 17586664 | Yes |
644 | 5633 | 2816.5 | 209.13 | 104.6 | The structure of negative emotional states: comparison of the Depression Anxiety Stress Scales (DASS) with the Beck Depression and Anxiety Inventories. | P F Lovibond, S H Lovibond | Behav Res Ther | 1995 | 7726811 | Yes |
645 | 2816 | 2816.0 | 60.74 | 60.7 | Nuclear factor-kappaB in cancer development and progression. | Michael Karin | Nature | 2006 | 16724054 | No |
646 | 2810 | 2810.0 | 53.63 | 53.6 | Elastic properties of lipid bilayers: theory and possible experiments. | W Helfrich | Z Naturforsch C | 1973 | 4273690 | Yes |
647 | 8429 | 2809.7 | 431.25 | 143.8 | Methods for dietary fiber, neutral detergent fiber, and nonstarch polysaccharides in relation to animal nutrition. | P J Van Soest, J B Robertson, B A Lewis | J Dairy Sci | 1991 | 1660498 | No |
648 | 2808 | 2808.0 | 70.93 | 70.9 | Analysis of gene diversity in subdivided populations. | M Nei | Proc Natl Acad Sci U S A | 1973 | 4519626 | Yes |
649 | 2807 | 2807.0 | 55.65 | 55.6 | Papillomaviruses and cancer: from basic studies to clinical application. | Harald zur Hausen | Nat Rev Cancer | 2002 | 12044010 | No |
650 | 2806 | 2806.0 | 55.44 | 55.4 | Interleukin-12 and the regulation of innate resistance and adaptive immunity. | Giorgio Trinchieri | Nat Rev Immunol | 2003 | 12563297 | No |
651 | 2805 | 2805.0 | 65.61 | 65.6 | Modularity and community structure in networks. | M E J Newman | Proc Natl Acad Sci U S A | 2006 | 16723398 | Yes |
652 | 5602 | 2801.0 | 152.28 | 76.1 | The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers. | J Vieira, J Messing | Gene | 1982 | 6295879 | Yes |
653 | 2800 | 2800.0 | 93.45 | 93.5 | Stereotaxic mapping of the monoamine pathways in the rat brain. | U Ungerstedt | Acta Physiol Scand Suppl | 1971 | 4109331 | Yes |
654 | 2798 | 2798.0 | 84.84 | 84.8 | Primate models of movement disorders of basal ganglia origin. | M R DeLong | Trends Neurosci | 1990 | 1695404 | No |
655 | 5595 | 2797.5 | 126.76 | 63.4 | Caspases: enemies within. | N A Thornberry, Y Lazebnik | Science | 1998 | 9721091 | No |
656 | 2795 | 2795.0 | 75.87 | 75.9 | Separation of leukocytes from blood and bone marrow. Introduction. | A Böyum | Scand J Clin Lab Invest Suppl | 1968 | 5707208 | Yes |
657 | 5578 | 2789.0 | 112.41 | 56.2 | Establishment in culture of pluripotential cells from mouse embryos. | M J Evans, M H Kaufman | Nature | 1981 | 7242681 | Yes |
658 | 5578 | 2789.0 | 77.8 | 38.9 | A method for determining the sedimentation behavior of enzymes: application to protein mixtures. | R G Martin, B N Ames | J Biol Chem | 1961 | 13767412 | Yes |
659 | 2788 | 2788.0 | 65.25 | 65.2 | Molecular chaperones in cellular protein folding. | F U Hartl | Nature | 1996 | 8637592 | No |
660 | 11141 | 2785.2 | 297.52 | 74.4 | Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. | P W Rigby, M Dieckmann, C Rhodes, P Berg | J Mol Biol | 1977 | 881736 | Yes |
661 | 5567 | 2783.5 | 192.56 | 96.3 | A method of comparing the areas under receiver operating characteristic curves derived from the same cases. | J A Hanley, B J McNeil | Radiology | 1983 | 6878708 | Yes |
662 | 5566 | 2783.0 | 172.9 | 86.5 | Computed tomography--an increasing source of radiation exposure. | David J Brenner, Eric J Hall | N Engl J Med | 2007 | 18046031 | No |
663 | 2782 | 2782.0 | 0.0 | 0.0 | Efficient trace-labelling of proteins with iodine. | A S McFARLANE | Nature | 1958 | 13566175 | Yes |
664 | 2780 | 2780.0 | 47.46 | 47.5 | Mechanisms underlying ubiquitination. | C M Pickart | Annu Rev Biochem | 2001 | 11395416 | No |
665 | 2779 | 2779.0 | 115.79 | 115.8 | Colorimetric assay of catalase. | A K Sinha | Anal Biochem | 1972 | 4556490 | Yes |
666 | 5550 | 2775.0 | 133.27 | 66.6 | Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. | S Marklund, G Marklund | Eur J Biochem | 1974 | 4215654 | Yes |
667 | 5548 | 2774.0 | 177.49 | 88.7 | Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. | J Sedlak, R H Lindsay | Anal Biochem | 1968 | 4973948 | Yes |
668 | 11084 | 2771.0 | 341.62 | 85.4 | Cancer statistics, 2010. | Ahmedin Jemal, Rebecca Siegel, Jiaquan Xu, Elizabeth Ward | CA Cancer J Clin | 2010 | 20610543 | Yes |
669 | 2765 | 2765.0 | 61.74 | 61.7 | Salt and drought stress signal transduction in plants. | Jian-Kang Zhu | Annu Rev Plant Biol | 2002 | 12221975 | No |
670 | 2765 | 2765.0 | 0.0 | 0.0 | Quantitative estimation of sialic acids. II. A colorimetric resorcinol-hydrochloric acid method. | L Svennerholm | Biochim Biophys Acta | 1957 | 13436486 | Yes |
671 | 2763 | 2763.0 | 112.88 | 112.9 | Microplastics in the marine environment. | Anthony L Andrady | Mar Pollut Bull | 2011 | 21742351 | No |
672 | 2759 | 2759.0 | 124.84 | 124.8 | Detecting alcoholism. The CAGE questionnaire. | J A Ewing | JAMA | 1984 | 6471323 | Yes |
673 | 2758 | 2758.0 | 105.16 | 105.2 | A simple technique for demonstrating centromeric heterochromatin. | A T Sumner | Exp Cell Res | 1972 | 4117921 | Yes |
674 | 8274 | 2758.0 | 189.1 | 63.0 | Pathogen recognition and innate immunity. | Shizuo Akira, Satoshi Uematsu, Osamu Takeuchi | Cell | 2006 | 16497588 | No |
675 | 2757 | 2757.0 | 66.45 | 66.5 | Cell death during development of the nervous system. | R W Oppenheim | Annu Rev Neurosci | 1991 | 2031577 | No |
676 | 5511 | 2755.5 | 109.54 | 54.8 | Innate immune recognition. | Charles A Janeway, Ruslan Medzhitov | Annu Rev Immunol | 2002 | 11861602 | No |
677 | 5505 | 2752.5 | 133.63 | 66.8 | Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. | D Hanahan, J Folkman | Cell | 1996 | 8756718 | No |
678 | 5496 | 2748.0 | 129.86 | 64.9 | Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. | F W Studier, B A Moffatt | J Mol Biol | 1986 | 3537305 | Yes |
679 | 5490 | 2745.0 | 85.24 | 42.6 | A modified uronic acid carbazole reaction. | T Bitter, H M Muir | Anal Biochem | 1962 | 13971270 | Yes |
680 | 2743 | 2743.0 | 68.39 | 68.4 | Models for the specific adhesion of cells to cells. | G I Bell | Science | 1978 | 347575 | No |
681 | 30128 | 2738.9 | 628.25 | 57.1 | Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. | Aravind Subramanian, Pablo Tamayo, Vamsi K Mootha, Sayan Mukherjee, Benjamin L Ebert, Michael A Gillette, Amanda Paulovich, Scott L Pomeroy, Todd R Golub, Eric S Lander, Jill P Mesirov | Proc Natl Acad Sci U S A | 2005 | 16199517 | Yes |
682 | 2736 | 2736.0 | 79.05 | 79.0 | Improving the quality of Web surveys: the Checklist for Reporting Results of Internet E-Surveys (CHERRIES). | Gunther Eysenbach | J Med Internet Res | 2004 | 15471760 | No |
683 | 5467 | 2733.5 | 167.02 | 83.5 | Glutathione. | A Meister, M E Anderson | Annu Rev Biochem | 1983 | 6137189 | No |
684 | 5460 | 2730.0 | 197.48 | 98.7 | Longitudinal data analysis for discrete and continuous outcomes. | S L Zeger, K Y Liang | Biometrics | 1986 | 3719049 | Yes |
685 | 2728 | 2728.0 | 69.19 | 69.2 | The genetic legacy of the Quaternary ice ages. | G Hewitt | Nature | 2000 | 10879524 | No |
686 | 2723 | 2723.0 | 70.33 | 70.3 | Predictive reward signal of dopamine neurons. | W Schultz | J Neurophysiol | 1998 | 9658025 | No |
687 | 2722 | 2722.0 | 53.17 | 53.2 | The danger model: a renewed sense of self. | Polly Matzinger | Science | 2002 | 11951032 | Yes |
688 | 8154 | 2718.0 | 353.31 | 117.8 | Detection of postnatal depression. Development of the 10-item Edinburgh Postnatal Depression Scale. | J L Cox, J M Holden, R Sagovsky | Br J Psychiatry | 1987 | 3651732 | Yes |
689 | 5434 | 2717.0 | 107.52 | 53.8 | High-efficiency transformation of mammalian cells by plasmid DNA. | C Chen, H Okayama | Mol Cell Biol | 1987 | 3670292 | Yes |
690 | 2717 | 2717.0 | 61.46 | 61.5 | Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. | S A Bustin | J Mol Endocrinol | 2000 | 11013345 | No |
691 | 2715 | 2715.0 | 102.56 | 102.6 | KDIGO clinical practice guidelines for acute kidney injury. | Arif Khwaja | Nephron Clin Pract | 2012 | 22890468 | No |
692 | 5426 | 2713.0 | 150.6 | 75.3 | Adherence to medication. | Lars Osterberg, Terrence Blaschke | N Engl J Med | 2005 | 16079372 | No |
693 | 8137 | 2712.3 | 174.76 | 58.3 | Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. | C M Gorman, L F Moffat, B H Howard | Mol Cell Biol | 1982 | 6960240 | Yes |
694 | 2710 | 2710.0 | 68.47 | 68.5 | Dietary pattern analysis: a new direction in nutritional epidemiology. | Frank B Hu | Curr Opin Lipidol | 2002 | 11790957 | No |
695 | 2709 | 2709.0 | 58.65 | 58.6 | Bone resorption by osteoclasts. | S L Teitelbaum | Science | 2000 | 10968780 | No |
696 | 5418 | 2709.0 | 126.78 | 63.4 | Autophagy in the pathogenesis of disease. | Beth Levine, Guido Kroemer | Cell | 2008 | 18191218 | No |
697 | 2708 | 2708.0 | 62.97 | 63.0 | Memory--a century of consolidation. | J L McGaugh | Science | 2000 | 10634773 | No |
698 | 5400 | 2700.0 | 168.92 | 84.5 | Accurate and simple analytic representation of the electron-gas correlation energy. | J P Perdew, Y Wang | Phys Rev B Condens Matter | 1992 | 10001404 | Yes |
699 | 2698 | 2698.0 | 103.04 | 103.0 | Role of nrf2 in oxidative stress and toxicity. | Qiang Ma | Annu Rev Pharmacol Toxicol | 2013 | 23294312 | No |
700 | 2694 | 2694.0 | 60.67 | 60.7 | Cell adhesion: the molecular basis of tissue architecture and morphogenesis. | B M Gumbiner | Cell | 1996 | 8608588 | No |
701 | 8082 | 2694.0 | 200.8 | 66.9 | MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment. | Sudhir Kumar, Koichiro Tamura, Masatoshi Nei | Brief Bioinform | 2004 | 15260895 | Yes |
702 | 5375 | 2687.5 | 257.57 | 128.8 | Stress, social support, and the buffering hypothesis. | S Cohen, T A Wills | Psychol Bull | 1985 | 3901065 | No |
703 | 5373 | 2686.5 | 153.84 | 76.9 | The Social Readjustment Rating Scale. | T H Holmes, R H Rahe | J Psychosom Res | 1967 | 6059863 | Yes |
704 | 10733 | 2683.2 | 227.94 | 57.0 | Cluster analysis and display of genome-wide expression patterns. | M B Eisen, P T Spellman, P O Brown, D Botstein | Proc Natl Acad Sci U S A | 1998 | 9843981 | Yes |
705 | 8040 | 2680.0 | 199.0 | 66.3 | Canonical sampling through velocity rescaling. | Giovanni Bussi, Davide Donadio, Michele Parrinello | J Chem Phys | 2007 | 17212484 | Yes |
706 | 18747 | 2678.1 | 719.4 | 102.8 | limma powers differential expression analyses for RNA-sequencing and microarray studies. | Matthew E Ritchie, Belinda Phipson, Di Wu, Yifang Hu, Charity W Law, Wei Shi, Gordon K Smyth | Nucleic Acids Res | 2015 | 25605792 | Yes |
707 | 2678 | 2678.0 | 75.78 | 75.8 | Parkinson's disease: clinical features and diagnosis. | J Jankovic | J Neurol Neurosurg Psychiatry | 2008 | 18344392 | No |
708 | 2676 | 2676.0 | 60.23 | 60.2 | Prostaglandins and leukotrienes: advances in eicosanoid biology. | C D Funk | Science | 2001 | 11729303 | No |
709 | 24043 | 2671.4 | 770.58 | 85.6 | STAR: ultrafast universal RNA-seq aligner. | Alexander Dobin, Carrie A Davis, Felix Schlesinger, Jorg Drenkow, Chris Zaleski, Sonali Jha, Philippe Batut, Mark Chaisson, Thomas R Gingeras | Bioinformatics | 2013 | 23104886 | Yes |
710 | 2668 | 2668.0 | 80.72 | 80.7 | SF-36 health survey update. | J E Ware | Spine (Phila Pa 1976) | 2000 | 11124729 | No |
711 | 10654 | 2663.5 | 314.68 | 78.7 | Establishing a standard definition for child overweight and obesity worldwide: international survey. | T J Cole, M C Bellizzi, K M Flegal, W H Dietz | BMJ | 2000 | 10797032 | Yes |
712 | 2658 | 2658.0 | 51.53 | 51.5 | Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. | Shimon Sakaguchi | Annu Rev Immunol | 2004 | 15032588 | No |
713 | 2657 | 2657.0 | 68.75 | 68.8 | Protein purification by affinity chromatography. Derivatizations of agarose and polyacrylamide beads. | P Cuatrecasas | J Biol Chem | 1970 | 5432796 | Yes |
714 | 2654 | 2654.0 | 23.32 | 23.3 | Satellite cell of skeletal muscle fibers. | A Mauro | J Biophys Biochem Cytol | 1961 | 13768451 | Yes |
715 | 2650 | 2650.0 | 57.4 | 57.4 | On the number of segregating sites in genetical models without recombination. | G A Watterson | Theor Popul Biol | 1975 | 1145509 | Yes |
716 | 2649 | 2649.0 | 69.85 | 69.8 | The magical number 4 in short-term memory: a reconsideration of mental storage capacity. | N Cowan | Behav Brain Sci | 2001 | 11515286 | Yes |
717 | 2641 | 2641.0 | 63.72 | 63.7 | T cell exhaustion. | E John Wherry | Nat Immunol | 2011 | 21739672 | No |
718 | 2638 | 2638.0 | 65.83 | 65.8 | The nerve growth factor 35 years later. | R Levi-Montalcini | Science | 1987 | 3306916 | No |
719 | 5276 | 2638.0 | 155.85 | 77.9 | Long-range corrected hybrid density functionals with damped atom-atom dispersion corrections. | Jeng-Da Chai, Martin Head-Gordon | Phys Chem Chem Phys | 2008 | 18989472 | Yes |
720 | 2637 | 2637.0 | 60.27 | 60.3 | Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface. | G P Smith | Science | 1985 | 4001944 | Yes |
721 | 5274 | 2637.0 | 180.78 | 90.4 | The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions. | S H Downs, N Black | J Epidemiol Community Health | 1998 | 9764259 | Yes |
722 | 2634 | 2634.0 | 81.77 | 81.8 | What are the functional consequences of neurocognitive deficits in schizophrenia? | M F Green | Am J Psychiatry | 1996 | 8610818 | No |
723 | 5257 | 2628.5 | 0.0 | 0.0 | Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid. | J D Watson, F H Crick | Nature | 1953 | 13054692 | Yes |
724 | 5249 | 2624.5 | 136.53 | 68.3 | Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. | L A Greene, A S Tischler | Proc Natl Acad Sci U S A | 1976 | 1065897 | Yes |
725 | 5249 | 2624.5 | 181.64 | 90.8 | Extracellular vesicles: exosomes, microvesicles, and friends. | Graça Raposo, Willem Stoorvogel | J Cell Biol | 2013 | 23420871 | No |
726 | 2624 | 2624.0 | 77.85 | 77.8 | The unfolded protein response: controlling cell fate decisions under ER stress and beyond. | Claudio Hetz | Nat Rev Mol Cell Biol | 2012 | 22251901 | No |
727 | 2621 | 2621.0 | 104.74 | 104.7 | The biology of oxygen radicals. | I Fridovich | Science | 1978 | 210504 | Yes |
728 | 5240 | 2620.0 | 117.11 | 58.6 | Signal transduction by receptors with tyrosine kinase activity. | A Ullrich, J Schlessinger | Cell | 1990 | 2158859 | No |
729 | 5235 | 2617.5 | 207.19 | 103.6 | A feature-integration theory of attention. | A M Treisman, G Gelade | Cogn Psychol | 1980 | 7351125 | Yes |
730 | 2612 | 2612.0 | 63.49 | 63.5 | Molecular basis of bacterial outer membrane permeability revisited. | Hiroshi Nikaido | Microbiol Mol Biol Rev | 2003 | 14665678 | No |
731 | 5223 | 2611.5 | 180.43 | 90.2 | A simple, rapid, and sensitive DNA assay procedure. | C Labarca, K Paigen | Anal Biochem | 1980 | 6158890 | Yes |
732 | 2611 | 2611.0 | 81.41 | 81.4 | Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. | B Samuelsson | Science | 1983 | 6301011 | Yes |
733 | 5221 | 2610.5 | 0.0 | 0.0 | Some quantitative uses of drug antagonists. | O Arunlakshana, H O Schild | Br J Pharmacol Chemother | 1959 | 13651579 | Yes |
734 | 2610 | 2610.0 | 116.82 | 116.8 | The membrane actions of anesthetics and tranquilizers. | P Seeman | Pharmacol Rev | 1972 | 4565956 | No |
735 | 2610 | 2610.0 | 58.97 | 59.0 | Vascular endothelial growth factor: basic science and clinical progress. | Napoleone Ferrara | Endocr Rev | 2004 | 15294883 | No |
736 | 2606 | 2606.0 | 74.5 | 74.5 | Formation and Structure of Self-Assembled Monolayers. | Abraham Ulman | Chem Rev | 1996 | 11848802 | Yes |
737 | 5209 | 2604.5 | 159.15 | 79.6 | Rapid isolation of high molecular weight plant DNA. | M G Murray, W F Thompson | Nucleic Acids Res | 1980 | 7433111 | Yes |
738 | 2597 | 2597.0 | 55.65 | 55.6 | G1 phase progression: cycling on cue. | C J Sherr | Cell | 1994 | 7954821 | No |
739 | 15550 | 2591.7 | 349.07 | 58.2 | Phaser crystallographic software. | Airlie J McCoy, Ralf W Grosse-Kunstleve, Paul D Adams, Martyn D Winn, Laurent C Storoni, Randy J Read | J Appl Crystallogr | 2007 | 19461840 | Yes |
740 | 5183 | 2591.5 | 101.51 | 50.8 | Untangling the ErbB signalling network. | Y Yarden, M X Sliwkowski | Nat Rev Mol Cell Biol | 2001 | 11252954 | No |
741 | 5182 | 2591.0 | 106.7 | 53.4 | MicroRNAs: small RNAs with a big role in gene regulation. | Lin He, Gregory J Hannon | Nat Rev Genet | 2004 | 15211354 | No |
742 | 2589 | 2589.0 | 62.23 | 62.2 | Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. | E C Butcher | Cell | 1991 | 1760836 | No |
743 | 2583 | 2583.0 | 62.54 | 62.5 | Cancer nanotechnology: opportunities and challenges. | Mauro Ferrari | Nat Rev Cancer | 2005 | 15738981 | No |
744 | 2582 | 2582.0 | 0.0 | 0.0 | The hydrolysis of rabbit y-globulin and antibodies with crystalline papain. | R R Porter | Biochem J | 1959 | 14434282 | Yes |
745 | 5158 | 2579.0 | 159.63 | 79.8 | The L-arginine-nitric oxide pathway. | S Moncada, A Higgs | N Engl J Med | 1993 | 7504210 | No |
746 | 2577 | 2577.0 | 73.08 | 73.1 | Delayed neuronal death in the gerbil hippocampus following ischemia. | T Kirino | Brain Res | 1982 | 7093691 | Yes |
747 | 2572 | 2572.0 | 56.92 | 56.9 | Epigenetics in cancer. | Manel Esteller | N Engl J Med | 2008 | 18337604 | No |
748 | 5132 | 2566.0 | 166.51 | 83.3 | The neural basis of drug craving: an incentive-sensitization theory of addiction. | T E Robinson, K C Berridge | Brain Res Brain Res Rev | 1993 | 8401595 | No |
749 | 2563 | 2563.0 | 53.52 | 53.5 | Evolving concepts of rheumatoid arthritis. | Gary S Firestein | Nature | 2003 | 12748655 | No |
750 | 2561 | 2561.0 | 36.35 | 36.4 | The catecholamine hypothesis of affective disorders: a review of supporting evidence. | J J Schildkraut | Am J Psychiatry | 1965 | 5319766 | No |
751 | 2560 | 2560.0 | 50.34 | 50.3 | Tumour-educated macrophages promote tumour progression and metastasis. | Jeffrey W Pollard | Nat Rev Cancer | 2004 | 14708027 | No |
752 | 2559 | 2559.0 | 68.29 | 68.3 | Dominant forces in protein folding. | K A Dill | Biochemistry | 1990 | 2207096 | No |
753 | 2559 | 2559.0 | 0.0 | 0.0 | The Estimation Of Pepsin, Trypsin, Papain, And Cathepsin With Hemoglobin. | M L Anson | J Gen Physiol | 1938 | 19873094 | Yes |
754 | 5116 | 2558.0 | 80.82 | 40.4 | A general method applicable to the search for similarities in the amino acid sequence of two proteins. | S B Needleman, C D Wunsch | J Mol Biol | 1970 | 5420325 | Yes |
755 | 2558 | 2558.0 | 0.0 | 0.0 | Zone electrophoresis in starch gels: group variations in the serum proteins of normal human adults. | O Smithies | Biochem J | 1955 | 13276348 | Yes |
756 | 2557 | 2557.0 | 103.73 | 103.7 | Qualitative research. Introducing focus groups. | J Kitzinger | BMJ | 1995 | 7633241 | Yes |
757 | 7644 | 2548.0 | 227.61 | 75.9 | FastTree 2--approximately maximum-likelihood trees for large alignments. | Morgan N Price, Paramvir S Dehal, Adam P Arkin | PLoS One | 2010 | 20224823 | Yes |
758 | 2547 | 2547.0 | 100.82 | 100.8 | Central sensitization: implications for the diagnosis and treatment of pain. | Clifford J Woolf | Pain | 2011 | 20961685 | No |
759 | 2546 | 2546.0 | 73.08 | 73.1 | Stress, adaptation, and disease. Allostasis and allostatic load. | B S McEwen | Ann N Y Acad Sci | 1998 | 9629234 | No |
760 | 2539 | 2539.0 | 26.63 | 26.6 | The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes. | S Boyden | J Exp Med | 1962 | 13872176 | Yes |
761 | 2538 | 2538.0 | 71.21 | 71.2 | Two-sided confidence intervals for the single proportion: comparison of seven methods. | R G Newcombe | Stat Med | 1998 | 9595616 | Yes |
762 | 2536 | 2536.0 | 51.91 | 51.9 | Telomere measurement by quantitative PCR. | Richard M Cawthon | Nucleic Acids Res | 2002 | 12000852 | Yes |
763 | 2535 | 2535.0 | 50.94 | 50.9 | Universal control mechanism regulating onset of M-phase. | P Nurse | Nature | 1990 | 2138713 | No |
764 | 7600 | 2533.3 | 261.71 | 87.2 | Effect of the damping function in dispersion corrected density functional theory. | Stefan Grimme, Stephan Ehrlich, Lars Goerigk | J Comput Chem | 2011 | 21370243 | Yes |
765 | 2531 | 2531.0 | 55.06 | 55.1 | Angiogenesis in life, disease and medicine. | Peter Carmeliet | Nature | 2005 | 16355210 | No |
766 | 5060 | 2530.0 | 273.39 | 136.7 | A diagnostic interview: the schedule for affective disorders and schizophrenia. | J Endicott, R L Spitzer | Arch Gen Psychiatry | 1978 | 678037 | Yes |
767 | 2530 | 2530.0 | 77.71 | 77.7 | Secretory products of macrophages. | C F Nathan | J Clin Invest | 1987 | 3543052 | No |
768 | 5049 | 2524.5 | 230.77 | 115.4 | Periodontal Disease In Pregnancy. Ii. Correlation Between Oral Hygiene And Periodontal Condtion. | J Silness, H Loe | Acta Odontol Scand | 1964 | 14158464 | Yes |
769 | 5042 | 2521.0 | 124.98 | 62.5 | Reactive oxygen species: metabolism, oxidative stress, and signal transduction. | Klaus Apel, Heribert Hirt | Annu Rev Plant Biol | 2004 | 15377225 | No |
770 | 2521 | 2521.0 | 70.24 | 70.2 | Physiology and neurobiology of stress and adaptation: central role of the brain. | Bruce S McEwen | Physiol Rev | 2007 | 17615391 | No |
771 | 10079 | 2519.8 | 459.08 | 114.8 | IQ-TREE: a fast and effective stochastic algorithm for estimating maximum-likelihood phylogenies. | Lam-Tung Nguyen, Heiko A Schmidt, Arndt von Haeseler, Bui Quang Minh | Mol Biol Evol | 2015 | 25371430 | Yes |
772 | 10073 | 2518.2 | 1517.45 | 379.4 | Cancer Statistics, 2021. | Rebecca L Siegel, Kimberly D Miller, Hannah E Fuchs, Ahmedin Jemal | CA Cancer J Clin | 2021 | 33433946 | Yes |
773 | 2518 | 2518.0 | 87.32 | 87.3 | A computational approach to edge detection. | J Canny | IEEE Trans Pattern Anal Mach Intell | 1986 | 21869365 | Yes |
774 | 2505 | 2505.0 | 61.52 | 61.5 | A mechanism for cognitive dynamics: neuronal communication through neuronal coherence. | Pascal Fries | Trends Cogn Sci | 2005 | 16150631 | No |
775 | 2504 | 2504.0 | 79.04 | 79.0 | Social cognitive theory: an agentic perspective. | A Bandura | Annu Rev Psychol | 2001 | 11148297 | Yes |
776 | 2503 | 2503.0 | 70.01 | 70.0 | Human gastric carcinogenesis: a multistep and multifactorial process--First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. | P Correa | Cancer Res | 1992 | 1458460 | No |
777 | 2501 | 2501.0 | 82.21 | 82.2 | A rating instrument for anxiety disorders. | W W Zung | Psychosomatics | 1971 | 5172928 | Yes |
778 | 2497 | 2497.0 | 44.97 | 45.0 | Wnt signaling and cancer. | P Polakis | Genes Dev | 2000 | 10921899 | No |
779 | 4993 | 2496.5 | 179.25 | 89.6 | Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril. | P J Fraker, J C Speck | Biochem Biophys Res Commun | 1978 | 637870 | Yes |
780 | 2491 | 2491.0 | 77.79 | 77.8 | The free-energy principle: a unified brain theory? | Karl Friston | Nat Rev Neurosci | 2010 | 20068583 | No |
781 | 9956 | 2489.0 | 412.17 | 103.0 | Cancer statistics, 2014. | Rebecca Siegel, Jiemin Ma, Zhaohui Zou, Ahmedin Jemal | CA Cancer J Clin | 2014 | 24399786 | Yes |
782 | 2486 | 2486.0 | 112.0 | 112.0 | Oxygen-dependent microbial killing by phagocytes (first of two parts). | B M Babior | N Engl J Med | 1978 | 24176 | Yes |
783 | 2485 | 2485.0 | 65.85 | 65.8 | Evaluating the quality of medical care. | A Donabedian | Milbank Mem Fund Q | 1966 | 5338568 | No |
784 | 2483 | 2483.0 | 81.28 | 81.3 | Perceived exertion as an indicator of somatic stress. | G Borg | Scand J Rehabil Med | 1970 | 5523831 | Yes |
785 | 4963 | 2481.5 | 141.43 | 70.7 | Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. | J V Durnin, J Womersley | Br J Nutr | 1974 | 4843734 | Yes |
786 | 2479 | 2479.0 | 106.82 | 106.8 | Statistics corner: A guide to appropriate use of correlation coefficient in medical research. | M M Mukaka | Malawi Med J | 2012 | 23638278 | Yes |
787 | 4953 | 2476.5 | 119.1 | 59.5 | Calculation of protein extinction coefficients from amino acid sequence data. | S C Gill, P H von Hippel | Anal Biochem | 1989 | 2610349 | Yes |
788 | 4948 | 2474.0 | 99.43 | 49.7 | Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. | D Bonnet, J E Dick | Nat Med | 1997 | 9212098 | Yes |
789 | 4946 | 2473.0 | 96.36 | 48.2 | CDK inhibitors: positive and negative regulators of G1-phase progression. | C J Sherr, J M Roberts | Genes Dev | 1999 | 10385618 | No |
790 | 7382 | 2460.7 | 201.27 | 67.1 | Quantum mechanical continuum solvation models. | Jacopo Tomasi, Benedetta Mennucci, Roberto Cammi | Chem Rev | 2005 | 16092826 | Yes |
791 | 2455 | 2455.0 | 147.6 | 147.6 | Hepatocellular Carcinoma. | Augusto Villanueva | N Engl J Med | 2019 | 30970190 | No |
792 | 2453 | 2453.0 | 54.46 | 54.5 | Social controls on cell survival and cell death. | M C Raff | Nature | 1992 | 1557121 | No |
793 | 4897 | 2448.5 | 215.12 | 107.6 | Clinical significance: a statistical approach to defining meaningful change in psychotherapy research. | N S Jacobson, P Truax | J Consult Clin Psychol | 1991 | 2002127 | Yes |
794 | 7343 | 2447.7 | 184.81 | 61.6 | RNA-Seq: a revolutionary tool for transcriptomics. | Zhong Wang, Mark Gerstein, Michael Snyder | Nat Rev Genet | 2009 | 19015660 | No |
795 | 2443 | 2443.0 | 47.26 | 47.3 | Getting started with yeast. | F Sherman | Methods Enzymol | 1991 | 2005794 | Yes |
796 | 2443 | 2443.0 | 0.0 | 0.0 | Transduction of linked genetic characters of the host by bacteriophage P1. | E S Lennox | Virology | 1955 | 13267987 | Yes |
797 | 2442 | 2442.0 | 65.78 | 65.8 | Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication. | H G Gratzner | Science | 1982 | 7123245 | Yes |
798 | 7325 | 2441.7 | 195.96 | 65.3 | Immunity, inflammation, and cancer. | Sergei I Grivennikov, Florian R Greten, Michael Karin | Cell | 2010 | 20303878 | No |
799 | 4883 | 2441.5 | 114.0 | 57.0 | Myeloid-derived suppressor cells as regulators of the immune system. | Dmitry I Gabrilovich, Srinivas Nagaraj | Nat Rev Immunol | 2009 | 19197294 | No |
800 | 4862 | 2431.0 | 145.05 | 72.5 | SPSS and SAS procedures for estimating indirect effects in simple mediation models. | Kristopher J Preacher, Andrew F Hayes | Behav Res Methods Instrum Comput | 2004 | 15641418 | Yes |
801 | 2429 | 2429.0 | 60.98 | 61.0 | Immunological and inflammatory functions of the interleukin-1 family. | Charles A Dinarello | Annu Rev Immunol | 2009 | 19302047 | No |
802 | 2423 | 2423.0 | 58.0 | 58.0 | Causes and consequences of microRNA dysregulation in cancer. | Carlo M Croce | Nat Rev Genet | 2009 | 19763153 | No |
803 | 9674 | 2418.5 | 254.55 | 63.6 | GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation. | Berk Hess, Carsten Kutzner, David van der Spoel, Erik Lindahl | J Chem Theory Comput | 2008 | 26620784 | Yes |
804 | 2415 | 2415.0 | 122.08 | 122.1 | Conservation of resources. A new attempt at conceptualizing stress. | S E Hobfoll | Am Psychol | 1989 | 2648906 | No |
805 | 4827 | 2413.5 | 119.94 | 60.0 | A global optimisation method for robust affine registration of brain images. | M Jenkinson, S Smith | Med Image Anal | 2001 | 11516708 | Yes |
806 | 4827 | 2413.5 | 125.56 | 62.8 | UniFrac: a new phylogenetic method for comparing microbial communities. | Catherine Lozupone, Rob Knight | Appl Environ Microbiol | 2005 | 16332807 | Yes |
807 | 7232 | 2410.7 | 206.2 | 68.7 | Bacterial biofilms: a common cause of persistent infections. | J W Costerton, P S Stewart, E P Greenberg | Science | 1999 | 10334980 | No |
808 | 2409 | 2409.0 | 92.42 | 92.4 | Missing data analysis: making it work in the real world. | John W Graham | Annu Rev Psychol | 2009 | 18652544 | No |
809 | 4812 | 2406.0 | 107.48 | 53.7 | Signal integration in the endoplasmic reticulum unfolded protein response. | David Ron, Peter Walter | Nat Rev Mol Cell Biol | 2007 | 17565364 | No |
810 | 2401 | 2401.0 | 52.28 | 52.3 | Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. | T Hunter | Cell | 1995 | 7834742 | No |
811 | 4799 | 2399.5 | 93.07 | 46.5 | The phosphatidylinositol 3-Kinase AKT pathway in human cancer. | Igor Vivanco, Charles L Sawyers | Nat Rev Cancer | 2002 | 12094235 | No |
812 | 7196 | 2398.7 | 186.26 | 62.1 | Cortical surface-based analysis. I. Segmentation and surface reconstruction. | A M Dale, B Fischl, M I Sereno | Neuroimage | 1999 | 9931268 | Yes |
813 | 2398 | 2398.0 | 76.83 | 76.8 | Plant products as antimicrobial agents. | M M Cowan | Clin Microbiol Rev | 1999 | 10515903 | No |
814 | 4785 | 2392.5 | 94.38 | 47.2 | Lipid rafts and signal transduction. | K Simons, D Toomre | Nat Rev Mol Cell Biol | 2000 | 11413487 | No |
815 | 2392 | 2392.0 | 0.0 | 0.0 | The information capacity of the human motor system in controlling the amplitude of movement. | P M Fitts | J Exp Psychol | 1954 | 13174710 | Yes |
816 | 4784 | 2392.0 | 119.87 | 59.9 | The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. | Karen Bedard, Karl-Heinz Krause | Physiol Rev | 2007 | 17237347 | No |
817 | 2386 | 2386.0 | 94.26 | 94.3 | The biology and function of fibroblasts in cancer. | Raghu Kalluri | Nat Rev Cancer | 2016 | 27550820 | No |
818 | 4758 | 2379.0 | 126.79 | 63.4 | Alzheimer's disease: the amyloid cascade hypothesis. | J A Hardy, G A Higgins | Science | 1992 | 1566067 | No |
819 | 2376 | 2376.0 | 60.08 | 60.1 | Inferring the historical patterns of biological evolution. | M Pagel | Nature | 1999 | 10553904 | Yes |
820 | 2376 | 2376.0 | 49.62 | 49.6 | Molecular physiology of P2X receptors. | R Alan North | Physiol Rev | 2002 | 12270951 | No |
821 | 2376 | 2376.0 | 49.92 | 49.9 | Cisplatin: mode of cytotoxic action and molecular basis of resistance. | Zahid H Siddik | Oncogene | 2003 | 14576837 | No |
822 | 2373 | 2373.0 | 73.09 | 73.1 | The role of positive emotions in positive psychology. The broaden-and-build theory of positive emotions. | B L Fredrickson | Am Psychol | 2001 | 11315248 | Yes |
823 | 4744 | 2372.0 | 151.71 | 75.9 | Microenvironmental regulation of tumor progression and metastasis. | Daniela F Quail, Johanna A Joyce | Nat Med | 2013 | 24202395 | No |
824 | 4743 | 2371.5 | 48.77 | 24.4 | Periodontal Disease In Pregnancy. I. Prevalence And Severity. | H Loe, J Silness | Acta Odontol Scand | 1963 | 14121956 | Yes |
825 | 2370 | 2370.0 | 82.32 | 82.3 | Doxil®--the first FDA-approved nano-drug: lessons learned. | Yechezkel Barenholz | J Control Release | 2012 | 22484195 | No |
826 | 4739 | 2369.5 | 120.24 | 60.1 | Management of hepatocellular carcinoma. | Jordi Bruix, Morris Sherman | Hepatology | 2005 | 16250051 | No |
827 | 2369 | 2369.0 | 107.83 | 107.8 | Structural Model Evaluation and Modification: An Interval Estimation Approach. | J H Steiger | Multivariate Behav Res | 1990 | 26794479 | Yes |
828 | 2368 | 2368.0 | 54.09 | 54.1 | A decade of molecular biology of retinoic acid receptors. | P Chambon | FASEB J | 1996 | 8801176 | No |
829 | 2368 | 2368.0 | 43.38 | 43.4 | Java Treeview--extensible visualization of microarray data. | Alok J Saldanha | Bioinformatics | 2004 | 15180930 | Yes |
830 | 2367 | 2367.0 | 80.66 | 80.7 | A rapid radiochemical method for the determination of choline acetyltransferase. | F Fonnum | J Neurochem | 1975 | 1113118 | Yes |
831 | 4733 | 2366.5 | 140.88 | 70.4 | Neural mechanisms of selective visual attention. | R Desimone, J Duncan | Annu Rev Neurosci | 1995 | 7605061 | No |
832 | 4724 | 2362.0 | 154.11 | 77.1 | Random-effects models for longitudinal data. | N M Laird, J H Ware | Biometrics | 1982 | 7168798 | Yes |
833 | 2362 | 2362.0 | 67.18 | 67.2 | Scaffolds in tissue engineering bone and cartilage. | D W Hutmacher | Biomaterials | 2000 | 11071603 | Yes |
834 | 4720 | 2360.0 | 103.66 | 51.8 | Death receptors: signaling and modulation. | A Ashkenazi, V M Dixit | Science | 1998 | 9721089 | No |
835 | 2357 | 2357.0 | 117.38 | 117.4 | Electroimmuno assay. | C B Laurell | Scand J Clin Lab Invest Suppl | 1972 | 4114358 | Yes |
836 | 2354 | 2354.0 | 57.28 | 57.3 | The anatomy and taxonomy of protein structure. | J S Richardson | Adv Protein Chem | 1981 | 7020376 | No |
837 | 2354 | 2354.0 | 75.99 | 76.0 | Epidemiology of viral hepatitis and hepatocellular carcinoma. | Hashem B El-Serag | Gastroenterology | 2012 | 22537432 | No |
838 | 2353 | 2353.0 | 101.79 | 101.8 | The Michigan alcoholism screening test: the quest for a new diagnostic instrument. | M L Selzer | Am J Psychiatry | 1971 | 5565851 | Yes |
839 | 2351 | 2351.0 | 51.85 | 51.9 | Rab GTPases as coordinators of vesicle traffic. | Harald Stenmark | Nat Rev Mol Cell Biol | 2009 | 19603039 | No |
840 | 2348 | 2348.0 | 43.21 | 43.2 | Targeting RAS signalling pathways in cancer therapy. | Julian Downward | Nat Rev Cancer | 2003 | 12509763 | No |
841 | 4695 | 2347.5 | 138.95 | 69.5 | Missing data: our view of the state of the art. | Joseph L Schafer, John W Graham | Psychol Methods | 2002 | 12090408 | Yes |
842 | 2346 | 2346.0 | 52.95 | 53.0 | The inflammatory reflex. | Kevin J Tracey | Nature | 2002 | 12490958 | No |
843 | 2345 | 2345.0 | 44.98 | 45.0 | Mechanisms of type-I- and type-II-interferon-mediated signalling. | Leonidas C Platanias | Nat Rev Immunol | 2005 | 15864272 | No |
844 | 4689 | 2344.5 | 97.74 | 48.9 | New functions for the matrix metalloproteinases in cancer progression. | Mikala Egeblad, Zena Werb | Nat Rev Cancer | 2002 | 11990853 | No |
845 | 2344 | 2344.0 | 51.01 | 51.0 | A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. | Douglas C Wallace | Annu Rev Genet | 2005 | 16285865 | No |
846 | 2343 | 2343.0 | 51.71 | 51.7 | Mitochondrial diseases in man and mouse. | D C Wallace | Science | 1999 | 10066162 | No |
847 | 7029 | 2343.0 | 70.26 | 23.4 | On The Nature Of Allosteric Transitions: A Plausible Model. | J Monod, J Wyman, J P Changeux | J Mol Biol | 1965 | 14343300 | Yes |
848 | 2342 | 2342.0 | 51.84 | 51.8 | The structure and regulation of protein phosphatases. | P Cohen | Annu Rev Biochem | 1989 | 2549856 | No |
849 | 2341 | 2341.0 | 77.9 | 77.9 | Working memory. | A Baddeley | Science | 1992 | 1736359 | No |
850 | 4681 | 2340.5 | 135.79 | 67.9 | Nonparametric statistical testing of EEG- and MEG-data. | Eric Maris, Robert Oostenveld | J Neurosci Methods | 2007 | 17517438 | Yes |
851 | 7018 | 2339.3 | 154.0 | 51.3 | The biology of VEGF and its receptors. | Napoleone Ferrara, Hans-Peter Gerber, Jennifer LeCouter | Nat Med | 2003 | 12778165 | No |
852 | 4674 | 2337.0 | 103.2 | 51.6 | Screening lambdagt recombinant clones by hybridization to single plaques in situ. | W D Benton, R W Davis | Science | 1977 | 322279 | Yes |
853 | 2333 | 2333.0 | 0.0 | 0.0 | Muscle structure and theories of contraction. | A F Huxley | Prog Biophys Biophys Chem | 1957 | 13485191 | Yes |
854 | 2333 | 2333.0 | 0.0 | 0.0 | Isolation by Distance. | S Wright | Genetics | 1943 | 17247074 | Yes |
855 | 4666 | 2333.0 | 100.14 | 50.1 | Judgment under Uncertainty: Heuristics and Biases. | A Tversky, D Kahneman | Science | 1974 | 17835457 | Yes |
856 | 2332 | 2332.0 | 84.31 | 84.3 | Calmodulin plays a pivotal role in cellular regulation. | W Y Cheung | Science | 1980 | 6243188 | No |
857 | 4658 | 2329.0 | 126.79 | 63.4 | Ab initio molecular-dynamics simulation of the liquid-metal-amorphous-semiconductor transition in germanium. | G Kresse, J Hafner | Phys Rev B Condens Matter | 1994 | 10010505 | Yes |
858 | 4649 | 2324.5 | 87.25 | 43.6 | A novel genetic system to detect protein-protein interactions. | S Fields, O Song | Nature | 1989 | 2547163 | Yes |
859 | 2324 | 2324.0 | 61.04 | 61.0 | A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. | P Chomczynski | Biotechniques | 1993 | 7692896 | Yes |
860 | 4648 | 2324.0 | 118.47 | 59.2 | Gold nanoparticles: assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology. | Marie-Christine Daniel, Didier Astruc | Chem Rev | 2004 | 14719978 | No |
861 | 4642 | 2321.0 | 129.81 | 64.9 | Quantitative film detection of 3H and 14C in polyacrylamide gels by fluorography. | R A Laskey, A D Mills | Eur J Biochem | 1975 | 1175627 | Yes |
862 | 2320 | 2320.0 | 46.52 | 46.5 | Stereochemistry of cooperative effects in haemoglobin. | M F Perutz | Nature | 1970 | 5528785 | Yes |
863 | 2319 | 2319.0 | 66.32 | 66.3 | Interleukin-1 and interleukin-1 antagonism. | C A Dinarello | Blood | 1991 | 1826616 | No |
864 | 4638 | 2319.0 | 131.11 | 65.6 | The number of people with glaucoma worldwide in 2010 and 2020. | H A Quigley, A T Broman | Br J Ophthalmol | 2006 | 16488940 | Yes |
865 | 2318 | 2318.0 | 57.56 | 57.6 | A model for receptor-regulated calcium entry. | J W Putney | Cell Calcium | 1986 | 2420465 | No |
866 | 4635 | 2317.5 | 126.49 | 63.2 | Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. | Michael D Fox, Marcus E Raichle | Nat Rev Neurosci | 2007 | 17704812 | No |
867 | 2316 | 2316.0 | 65.76 | 65.8 | Inositol phospholipids and cell surface receptor function. | R H Michell | Biochim Biophys Acta | 1975 | 164246 | No |
868 | 2316 | 2316.0 | 55.32 | 55.3 | Ischemic cell death in brain neurons. | P Lipton | Physiol Rev | 1999 | 10508238 | No |
869 | 4630 | 2315.0 | 194.68 | 97.3 | The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. | H P Misra, I Fridovich | J Biol Chem | 1972 | 4623845 | Yes |
870 | 6938 | 2312.7 | 183.52 | 61.2 | Regularization Paths for Generalized Linear Models via Coordinate Descent. | Jerome Friedman, Trevor Hastie, Rob Tibshirani | J Stat Softw | 2010 | 20808728 | Yes |
871 | 2311 | 2311.0 | 90.05 | 90.0 | Effective physician-patient communication and health outcomes: a review. | M A Stewart | CMAJ | 1995 | 7728691 | Yes |
872 | 4621 | 2310.5 | 160.39 | 80.2 | The biofilm matrix. | Hans-Curt Flemming, Jost Wingender | Nat Rev Microbiol | 2010 | 20676145 | No |
873 | 2307 | 2307.0 | 57.06 | 57.1 | Bcl-2 and the regulation of programmed cell death. | J C Reed | J Cell Biol | 1994 | 8294493 | No |
874 | 2306 | 2306.0 | 79.45 | 79.5 | Gctf: Real-time CTF determination and correction. | Kai Zhang | J Struct Biol | 2016 | 26592709 | Yes |
875 | 4610 | 2305.0 | 121.92 | 61.0 | Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. | C W Elston, I O Ellis | Histopathology | 1991 | 1757079 | Yes |
876 | 4605 | 2302.5 | 102.18 | 51.1 | AKT/PKB signaling: navigating downstream. | Brendan D Manning, Lewis C Cantley | Cell | 2007 | 17604717 | No |
877 | 2301 | 2301.0 | 48.67 | 48.7 | NOX enzymes and the biology of reactive oxygen. | J David Lambeth | Nat Rev Immunol | 2004 | 15039755 | No |
878 | 4600 | 2300.0 | 78.03 | 39.0 | High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study. | M N Berry, D S Friend | J Cell Biol | 1969 | 4900611 | Yes |
879 | 4598 | 2299.0 | 74.11 | 37.1 | On the size of the active site in proteases. I. Papain. | I Schechter, A Berger | Biochem Biophys Res Commun | 1967 | 6035483 | Yes |
880 | 4594 | 2297.0 | 115.86 | 57.9 | Acute-phase proteins and other systemic responses to inflammation. | C Gabay, I Kushner | N Engl J Med | 1999 | 9971870 | No |
881 | 2296 | 2296.0 | 71.56 | 71.6 | Reactive oxygen species and the central nervous system. | B Halliwell | J Neurochem | 1992 | 1402908 | No |
882 | 2293 | 2293.0 | 56.26 | 56.3 | An index to quantify an individual's scientific research output. | J E Hirsch | Proc Natl Acad Sci U S A | 2005 | 16275915 | Yes |
883 | 4579 | 2289.5 | 116.11 | 58.1 | A receptor-mediated pathway for cholesterol homeostasis. | M S Brown, J L Goldstein | Science | 1986 | 3513311 | No |
884 | 2289 | 2289.0 | 19.33 | 19.3 | Mechanism Of Sustained-Action Medication. Theoretical Analysis Of Rate Of Release Of Solid Drugs Dispersed In Solid Matrices. | T Higuchi | J Pharm Sci | 1963 | 14088963 | Yes |
885 | 2287 | 2287.0 | 49.46 | 49.5 | Nitric oxide and the immune response. | C Bogdan | Nat Immunol | 2001 | 11577346 | No |
886 | 2287 | 2287.0 | 58.16 | 58.2 | Network pharmacology: the next paradigm in drug discovery. | Andrew L Hopkins | Nat Chem Biol | 2008 | 18936753 | No |
887 | 2286 | 2286.0 | 45.29 | 45.3 | SV40-transformed simian cells support the replication of early SV40 mutants. | Y Gluzman | Cell | 1981 | 6260373 | Yes |
888 | 4572 | 2286.0 | 88.97 | 44.5 | Mechanisms of TGF-beta signaling from cell membrane to the nucleus. | Yigong Shi, Joan Massagué | Cell | 2003 | 12809600 | No |
889 | 2285 | 2285.0 | 56.33 | 56.3 | Contrasting mechanisms of defense against biotrophic and necrotrophic pathogens. | Jane Glazebrook | Annu Rev Phytopathol | 2005 | 16078883 | No |
890 | 2285 | 2285.0 | 61.85 | 61.9 | Intestinal mucosal barrier function in health and disease. | Jerrold R Turner | Nat Rev Immunol | 2009 | 19855405 | No |
891 | 4569 | 2284.5 | 89.74 | 44.9 | The interpretation of protein structures: estimation of static accessibility. | B Lee, F M Richards | J Mol Biol | 1971 | 5551392 | Yes |
892 | 2283 | 2283.0 | 78.43 | 78.4 | Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. | F F Jöbsis | Science | 1977 | 929199 | Yes |
893 | 4564 | 2282.0 | 167.69 | 83.8 | Self-rated health and mortality: a review of twenty-seven community studies. | E L Idler, Y Benyamini | J Health Soc Behav | 1997 | 9097506 | No |
894 | 4564 | 2282.0 | 107.43 | 53.7 | Protein misfolding, functional amyloid, and human disease. | Fabrizio Chiti, Christopher M Dobson | Annu Rev Biochem | 2006 | 16756495 | No |
895 | 2279 | 2279.0 | 93.97 | 94.0 | The validity and practicality of sun-reactive skin types I through VI. | T B Fitzpatrick | Arch Dermatol | 1988 | 3377516 | Yes |
896 | 4557 | 2278.5 | 166.91 | 83.5 | The attention system of the human brain. | M I Posner, S E Petersen | Annu Rev Neurosci | 1990 | 2183676 | No |
897 | 2277 | 2277.0 | 76.17 | 76.2 | Glutamate, nitric oxide and cell-cell signalling in the nervous system. | J Garthwaite | Trends Neurosci | 1991 | 1708538 | No |
898 | 2277 | 2277.0 | 0.0 | 0.0 | [Rapid physiological coagulation method in determination of fibrinogen]. | A Clauss | Acta Haematol | 1957 | 13434757 | Yes |
899 | 2275 | 2275.0 | 69.13 | 69.1 | A two process model of sleep regulation. | A A Borbély | Hum Neurobiol | 1982 | 7185792 | Yes |
900 | 9100 | 2275.0 | 216.74 | 54.2 | Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. | C A Lipinski, F Lombardo, B W Dominy, P J Feeney | Adv Drug Deliv Rev | 2001 | 11259830 | No |
901 | 2273 | 2273.0 | 53.11 | 53.1 | Specification of cerebral cortical areas. | P Rakic | Science | 1988 | 3291116 | No |
902 | 2273 | 2273.0 | 49.2 | 49.2 | Chemokines and leukocyte traffic. | M Baggiolini | Nature | 1998 | 9560152 | No |
903 | 4546 | 2273.0 | 111.22 | 55.6 | Nonparametric permutation tests for functional neuroimaging: a primer with examples. | Thomas E Nichols, Andrew P Holmes | Hum Brain Mapp | 2002 | 11747097 | Yes |
904 | 2270 | 2270.0 | 42.82 | 42.8 | Histone acetylation in chromatin structure and transcription. | M Grunstein | Nature | 1997 | 9311776 | No |
905 | 2269 | 2269.0 | 57.56 | 57.6 | A theory of cortical responses. | Karl Friston | Philos Trans R Soc Lond B Biol Sci | 2005 | 15937014 | No |
906 | 2269 | 2269.0 | 104.56 | 104.6 | Deep learning in neural networks: an overview. | Jürgen Schmidhuber | Neural Netw | 2015 | 25462637 | No |
907 | 2264 | 2264.0 | 71.0 | 71.0 | Human error: models and management. | J Reason | BMJ | 2000 | 10720363 | Yes |
908 | 4528 | 2264.0 | 121.99 | 61.0 | Application of phylogenetic networks in evolutionary studies. | Daniel H Huson, David Bryant | Mol Biol Evol | 2006 | 16221896 | Yes |
909 | 2261 | 2261.0 | 47.24 | 47.2 | Application of a microtechnique to viral serological investigations. | J L Sever | J Immunol | 1962 | 13910995 | Yes |
910 | 2260 | 2260.0 | 60.05 | 60.0 | The importance of selenium to human health. | M P Rayman | Lancet | 2000 | 10963212 | No |
911 | 2259 | 2259.0 | 68.91 | 68.9 | Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM. | R A DeFronzo | Diabetes | 1988 | 3289989 | No |
912 | 2254 | 2254.0 | 58.27 | 58.3 | The blood-brain barrier in health and chronic neurodegenerative disorders. | Berislav V Zlokovic | Neuron | 2008 | 18215617 | No |
913 | 9015 | 2253.8 | 197.02 | 49.3 | Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. | A Krogh, B Larsson, G von Heijne, E L Sonnhammer | J Mol Biol | 2001 | 11152613 | Yes |
914 | 4507 | 2253.5 | 94.98 | 47.5 | Mass spectrometry-based proteomics. | Ruedi Aebersold, Matthias Mann | Nature | 2003 | 12634793 | No |
915 | 4498 | 2249.0 | 102.83 | 51.4 | A simple and very efficient method for generating cDNA libraries. | U Gubler, B J Hoffman | Gene | 1983 | 6198242 | Yes |
916 | 2249 | 2249.0 | 44.37 | 44.4 | The molecular biology of memory storage: a dialogue between genes and synapses. | E R Kandel | Science | 2001 | 11691980 | No |
917 | 2247 | 2247.0 | 73.05 | 73.0 | Eye movements in reading and information processing: 20 years of research. | K Rayner | Psychol Bull | 1998 | 9849112 | No |
918 | 2245 | 2245.0 | 61.53 | 61.5 | Molecular diversity of glutamate receptors and implications for brain function. | S Nakanishi | Science | 1992 | 1329206 | No |
919 | 2244 | 2244.0 | 49.13 | 49.1 | Intracellular aspects of the process of protein synthesis. | G Palade | Science | 1975 | 1096303 | No |
920 | 2244 | 2244.0 | 75.15 | 75.2 | Simplified calculation of body-surface area. | R D Mosteller | N Engl J Med | 1987 | 3657876 | Yes |
921 | 2244 | 2244.0 | 0.0 | 0.0 | Studies on lysogenesis. I. The mode of phage liberation by lysogenic Escherichia coli. | G Bertani | J Bacteriol | 1951 | 14888646 | Yes |
922 | 2243 | 2243.0 | 109.27 | 109.3 | Mechanisms of action of transmitters and other substances on smooth muscle. | T B Bolton | Physiol Rev | 1979 | 37533 | No |
923 | 2242 | 2242.0 | 59.92 | 59.9 | Carbonic anhydrases: novel therapeutic applications for inhibitors and activators. | Claudiu T Supuran | Nat Rev Drug Discov | 2008 | 18167490 | No |
924 | 2240 | 2240.0 | 54.94 | 54.9 | Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide to nitrocellulose. | J Kyhse-Andersen | J Biochem Biophys Methods | 1984 | 6530509 | Yes |
925 | 2240 | 2240.0 | 53.08 | 53.1 | Protein kinase C and lipid signaling for sustained cellular responses. | Y Nishizuka | FASEB J | 1995 | 7737456 | No |
926 | 2240 | 2240.0 | 52.84 | 52.8 | Mechanisms and genes of cellular suicide. | H Steller | Science | 1995 | 7878463 | No |
927 | 2239 | 2239.0 | 55.93 | 55.9 | RGD and other recognition sequences for integrins. | E Ruoslahti | Annu Rev Cell Dev Biol | 1996 | 8970741 | No |
928 | 2239 | 2239.0 | 58.76 | 58.8 | MYC on the path to cancer. | Chi V Dang | Cell | 2012 | 22464321 | No |
929 | 2238 | 2238.0 | 83.6 | 83.6 | Specific impairments of planning. | T Shallice | Philos Trans R Soc Lond B Biol Sci | 1982 | 6125971 | Yes |
930 | 2235 | 2235.0 | 77.54 | 77.5 | Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases. | B N Ames | Science | 1983 | 6351251 | No |
931 | 2234 | 2234.0 | 123.0 | 123.0 | Determination and quantification of content validity. | M R Lynn | Nurs Res | 1986 | 3640358 | Yes |
932 | 2234 | 2234.0 | 72.86 | 72.9 | Qualitative research: standards, challenges, and guidelines. | K Malterud | Lancet | 2001 | 11513933 | Yes |
933 | 2231 | 2231.0 | 70.73 | 70.7 | Spinal and supraspinal factors in human muscle fatigue. | S C Gandevia | Physiol Rev | 2001 | 11581501 | No |
934 | 2231 | 2231.0 | 53.58 | 53.6 | Lead- and drug-like compounds: the rule-of-five revolution. | Christopher A Lipinski | Drug Discov Today Technol | 2004 | 24981612 | Yes |
935 | 4455 | 2227.5 | 107.85 | 53.9 | Regulation of the mevalonate pathway. | J L Goldstein, M S Brown | Nature | 1990 | 1967820 | No |
936 | 4453 | 2226.5 | 128.99 | 64.5 | Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. | C J Murray, A D Lopez | Lancet | 1997 | 9167458 | Yes |
937 | 2226 | 2226.0 | 49.04 | 49.0 | The regulation of AP-1 activity by mitogen-activated protein kinases. | M Karin | J Biol Chem | 1995 | 7622446 | No |
938 | 4451 | 2225.5 | 98.13 | 49.1 | Organization and expression of eucaryotic split genes coding for proteins. | R Breathnach, P Chambon | Annu Rev Biochem | 1981 | 6791577 | No |
939 | 2225 | 2225.0 | 57.82 | 57.8 | Working memory: looking back and looking forward. | Alan Baddeley | Nat Rev Neurosci | 2003 | 14523382 | No |
940 | 4448 | 2224.0 | 39.76 | 19.9 | A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. | J E TILL, E A McCULLOCH | Radiat Res | 1961 | 13776896 | Yes |
941 | 4444 | 2222.0 | 87.96 | 44.0 | Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. | T V Bliss, T Lomo | J Physiol | 1973 | 4727084 | Yes |
942 | 2221 | 2221.0 | 536.14 | 536.1 | Hallmarks of Cancer: New Dimensions. | Douglas Hanahan | Cancer Discov | 2022 | 35022204 | No |
943 | 2218 | 2218.0 | 68.5 | 68.5 | Biodiesel from microalgae. | Yusuf Chisti | Biotechnol Adv | 2007 | 17350212 | No |
944 | 2218 | 2218.0 | 63.54 | 63.5 | TGFβ signalling in context. | Joan Massagué | Nat Rev Mol Cell Biol | 2012 | 22992590 | No |
945 | 4435 | 2217.5 | 91.2 | 45.6 | The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin. | J A Spudich, S Watt | J Biol Chem | 1971 | 4254541 | Yes |
946 | 2216 | 2216.0 | 53.96 | 54.0 | Animal mitochondrial genomes. | J L Boore | Nucleic Acids Res | 1999 | 10101183 | No |
947 | 2216 | 2216.0 | 58.25 | 58.2 | Epidemiology of insomnia: what we know and what we still need to learn. | Maurice M Ohayon | Sleep Med Rev | 2002 | 12531146 | Yes |
948 | 4431 | 2215.5 | 108.0 | 54.0 | A scaling normalization method for differential expression analysis of RNA-seq data. | Mark D Robinson, Alicia Oshlack | Genome Biol | 2010 | 20196867 | Yes |
949 | 17715 | 2214.4 | 559.2 | 69.9 | The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. | D M Nathan, S Genuth, J Lachin, P Cleary, O Crofford, M Davis, L Rand, C Siebert | N Engl J Med | 1993 | 8366922 | Yes |
950 | 2213 | 2213.0 | 137.4 | 137.4 | Presidential Address-1976. Social support as a moderator of life stress. | S Cobb | Psychosom Med | 1976 | 981490 | Yes |
951 | 2212 | 2212.0 | 68.05 | 68.0 | Prooxidant states and tumor promotion. | P A Cerutti | Science | 1985 | 2981433 | No |
952 | 2212 | 2212.0 | 83.35 | 83.3 | Role of endothelium in responses of vascular smooth muscle. | R F Furchgott | Circ Res | 1983 | 6313250 | No |
953 | 2211 | 2211.0 | 64.32 | 64.3 | Hazards of heavy metal contamination. | Lars Järup | Br Med Bull | 2003 | 14757716 | No |
954 | 4421 | 2210.5 | 96.28 | 48.1 | Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. | F Sallusto, A Lanzavecchia | J Exp Med | 1994 | 8145033 | Yes |
955 | 4420 | 2210.0 | 99.27 | 49.6 | The Bcl-2 protein family: arbiters of cell survival. | J M Adams, S Cory | Science | 1998 | 9735050 | No |
956 | 2209 | 2209.0 | 112.74 | 112.7 | The antibiotic resistance crisis: part 1: causes and threats. | C Lee Ventola | P T | 2015 | 25859123 | Yes |
957 | 2205 | 2205.0 | 65.46 | 65.5 | Diagnosis of Alzheimer's disease. | Z S Khachaturian | Arch Neurol | 1985 | 2864910 | Yes |
958 | 4402 | 2201.0 | 119.41 | 59.7 | A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. | Y Matsumura, H Maeda | Cancer Res | 1986 | 2946403 | Yes |
959 | 4401 | 2200.5 | 99.14 | 49.6 | Brown adipose tissue: function and physiological significance. | Barbara Cannon, Jan Nedergaard | Physiol Rev | 2004 | 14715917 | No |
960 | 2199 | 2199.0 | 89.1 | 89.1 | Role of Streptococcus mutans in human dental decay. | W J Loesche | Microbiol Rev | 1986 | 3540569 | No |
961 | 2198 | 2198.0 | 69.11 | 69.1 | Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. | W A Craig | Clin Infect Dis | 1998 | 9455502 | No |
962 | 2197 | 2197.0 | 57.52 | 57.5 | Pancreatic cancer. | Manuel Hidalgo | N Engl J Med | 2010 | 20427809 | No |
963 | 2195 | 2195.0 | 54.9 | 54.9 | Removal of fatty acids from serum albumin by charcoal treatment. | R F Chen | J Biol Chem | 1967 | 6016603 | Yes |
964 | 2194 | 2194.0 | 61.87 | 61.9 | Hybrid porous solids: past, present, future. | Gérard Férey | Chem Soc Rev | 2008 | 18197340 | Yes |
965 | 2192 | 2192.0 | 41.36 | 41.4 | Shelterin: the protein complex that shapes and safeguards human telomeres. | Titia de Lange | Genes Dev | 2005 | 16166375 | No |
966 | 2191 | 2191.0 | 79.21 | 79.2 | Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminals. | H W Steinbusch | Neuroscience | 1981 | 7017455 | Yes |
967 | 2191 | 2191.0 | 63.82 | 63.8 | Social determinants of health inequalities. | Michael Marmot | Lancet | 2005 | 15781105 | Yes |
968 | 4376 | 2188.0 | 125.29 | 62.6 | Distributed hierarchical processing in the primate cerebral cortex. | D J Felleman, D C Van Essen | Cereb Cortex | 1991 | 1822724 | No |
969 | 2184 | 2184.0 | 55.64 | 55.6 | Standardized low-resolution brain electromagnetic tomography (sLORETA): technical details. | R D Pascual-Marqui | Methods Find Exp Clin Pharmacol | 2002 | 12575463 | No |
970 | 2183 | 2183.0 | 48.45 | 48.5 | Chemokines. | B J Rollins | Blood | 1997 | 9242519 | No |
971 | 2180 | 2180.0 | 65.28 | 65.3 | PsychoPy--Psychophysics software in Python. | Jonathan W Peirce | J Neurosci Methods | 2007 | 17254636 | Yes |
972 | 2179 | 2179.0 | 86.54 | 86.5 | Approximate entropy as a measure of system complexity. | S M Pincus | Proc Natl Acad Sci U S A | 1991 | 11607165 | Yes |
973 | 19611 | 2179.0 | 935.53 | 103.9 | Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. | Jacques Ferlay, Isabelle Soerjomataram, Rajesh Dikshit, Sultan Eser, Colin Mathers, Marise Rebelo, Donald Maxwell Parkin, David Forman, Freddie Bray | Int J Cancer | 2015 | 25220842 | Yes |
974 | 4356 | 2178.0 | 111.23 | 55.6 | Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. | M Matsuda, R A DeFronzo | Diabetes Care | 1999 | 10480510 | Yes |
975 | 2177 | 2177.0 | 46.49 | 46.5 | Complement. First of two parts. | M J Walport | N Engl J Med | 2001 | 11287977 | No |
976 | 2176 | 2176.0 | 90.63 | 90.6 | A systematic method for clinical description and classification of personality variants. A proposal. | C R Cloninger | Arch Gen Psychiatry | 1987 | 3579504 | Yes |
977 | 2174 | 2174.0 | 53.22 | 53.2 | Breast cancer and hormone-replacement therapy in the Million Women Study. | Valerie Beral | Lancet | 2003 | 12927427 | Yes |
978 | 6517 | 2172.3 | 250.63 | 83.5 | Glucose clamp technique: a method for quantifying insulin secretion and resistance. | R A DeFronzo, J D Tobin, R Andres | Am J Physiol | 1979 | 382871 | Yes |
979 | 2172 | 2172.0 | 47.3 | 47.3 | The distribution of secondary growths in cancer of the breast. 1889. | S Paget | Cancer Metastasis Rev | 1989 | 2673568 | No |
980 | 2169 | 2169.0 | 53.73 | 53.7 | P-LINCS: A Parallel Linear Constraint Solver for Molecular Simulation. | Berk Hess | J Chem Theory Comput | 2008 | 26619985 | Yes |
981 | 2167 | 2167.0 | 65.75 | 65.8 | Fetal origins of coronary heart disease. | D J Barker | BMJ | 1995 | 7613432 | No |
982 | 2165 | 2165.0 | 71.53 | 71.5 | A classification of glycosyl hydrolases based on amino acid sequence similarities. | B Henrissat | Biochem J | 1991 | 1747104 | Yes |
983 | 2165 | 2165.0 | 75.31 | 75.3 | Large-scale brain networks and psychopathology: a unifying triple network model. | Vinod Menon | Trends Cogn Sci | 2011 | 21908230 | No |
984 | 2161 | 2161.0 | 41.82 | 41.8 | Protein modules and signalling networks. | T Pawson | Nature | 1995 | 7531822 | No |
985 | 2161 | 2161.0 | 58.63 | 58.6 | Biofilms: microbial life on surfaces. | Rodney M Donlan | Emerg Infect Dis | 2002 | 12194761 | No |
986 | 8643 | 2160.8 | 209.07 | 52.3 | Matrix elasticity directs stem cell lineage specification. | Adam J Engler, Shamik Sen, H Lee Sweeney, Dennis E Discher | Cell | 2006 | 16923388 | Yes |
987 | 2160 | 2160.0 | 60.04 | 60.0 | Superoxide radical and superoxide dismutases. | I Fridovich | Annu Rev Biochem | 1995 | 7574505 | No |
988 | 2160 | 2160.0 | 69.62 | 69.6 | Keratoconus. | Y S Rabinowitz | Surv Ophthalmol | 1998 | 9493273 | No |
989 | 4319 | 2159.5 | 0.0 | 0.0 | Loss of recent memory after bilateral hippocampal lesions. | W B Scoville, B Milner | J Neurol Neurosurg Psychiatry | 1957 | 13406589 | Yes |
990 | 4317 | 2158.5 | 104.52 | 52.3 | Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. | Michael T Lin, M Flint Beal | Nature | 2006 | 17051205 | No |
991 | 4316 | 2158.0 | 148.01 | 74.0 | Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method. | R B Devereux, N Reichek | Circulation | 1977 | 138494 | Yes |
992 | 2156 | 2156.0 | 47.95 | 48.0 | A clearer vision for in vivo imaging. | R Weissleder | Nat Biotechnol | 2001 | 11283581 | No |
993 | 2154 | 2154.0 | 58.33 | 58.3 | The episodic buffer: a new component of working memory? | A Baddeley | Trends Cogn Sci | 2000 | 11058819 | Yes |
994 | 2154 | 2154.0 | 31.04 | 31.0 | Sedimentation Studies Of The Size And Shape Of Dna. | F W Studier | J Mol Biol | 1965 | 14290352 | Yes |
995 | 6458 | 2152.7 | 131.58 | 43.9 | Immunochemical quantitation of antigens by single radial immunodiffusion. | G Mancini, A O Carbonara, J F Heremans | Immunochemistry | 1965 | 4956917 | Yes |
996 | 2151 | 2151.0 | 49.45 | 49.5 | Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. | G Trinchieri | Annu Rev Immunol | 1995 | 7612223 | No |
997 | 4298 | 2149.0 | 111.73 | 55.9 | ATHENA, ARTEMIS, HEPHAESTUS: data analysis for X-ray absorption spectroscopy using IFEFFIT. | B Ravel, M Newville | J Synchrotron Radiat | 2005 | 15968136 | Yes |
998 | 4297 | 2148.5 | 81.22 | 40.6 | Variations in pattern of pubertal changes in girls. | W A Marshall, J M Tanner | Arch Dis Child | 1969 | 5785179 | Yes |
999 | 2148 | 2148.0 | 48.9 | 48.9 | Pathways towards and away from Alzheimer's disease. | Mark P Mattson | Nature | 2004 | 15295589 | No |
1000 | 4294 | 2147.0 | 100.8 | 50.4 | Assembly of asparagine-linked oligosaccharides. | R Kornfeld, S Kornfeld | Annu Rev Biochem | 1985 | 3896128 | No |
1001 | 4292 | 2146.0 | 123.53 | 61.8 | Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. | J S Beckman, W H Koppenol | Am J Physiol | 1996 | 8944624 | No |
1002 | 2145 | 2145.0 | 0.0 | 0.0 | Analysis of tissue and arterial blood temperatures in the resting human forearm. | H H Pennes | J Appl Physiol | 1948 | 18887578 | Yes |
1003 | 4288 | 2144.0 | 107.39 | 53.7 | Function and activation of NF-kappa B in the immune system. | P A Baeuerle, T Henkel | Annu Rev Immunol | 1994 | 8011280 | No |
1004 | 2144 | 2144.0 | 54.12 | 54.1 | The extracellular matrix: not just pretty fibrils. | Richard O Hynes | Science | 2009 | 19965464 | No |
1005 | 2141 | 2141.0 | 54.75 | 54.8 | Descending control of pain. | Mark J Millan | Prog Neurobiol | 2002 | 12034378 | No |
1006 | 6423 | 2141.0 | 191.17 | 63.7 | The brain's default network: anatomy, function, and relevance to disease. | Randy L Buckner, Jessica R Andrews-Hanna, Daniel L Schacter | Ann N Y Acad Sci | 2008 | 18400922 | No |
1007 | 2140 | 2140.0 | 55.84 | 55.8 | The molecular pathology of Alzheimer's disease. | D J Selkoe | Neuron | 1991 | 1673054 | No |
1008 | 2140 | 2140.0 | 61.21 | 61.2 | The energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers. | D E Atkinson | Biochemistry | 1968 | 4972613 | Yes |
1009 | 4275 | 2137.5 | 102.33 | 51.2 | Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. | Hashem B El-Serag, K Lenhard Rudolph | Gastroenterology | 2007 | 17570226 | No |
1010 | 2137 | 2137.0 | 0.0 | 0.0 | A new specific color reaction of hexuronic acids. | Z Dische | J Biol Chem | 1947 | 20281638 | Yes |
1011 | 6408 | 2136.0 | 184.98 | 61.7 | Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. | C E Murry, R B Jennings, K A Reimer | Circulation | 1986 | 3769170 | Yes |
1012 | 4270 | 2135.0 | 73.88 | 36.9 | A Simplified Lead Citrate Stain For Use In Electron Microscopy. | J H Venable, R Coggeshall | J Cell Biol | 1965 | 14287192 | Yes |
1013 | 8524 | 2131.0 | 173.17 | 43.3 | WebLogo: a sequence logo generator. | Gavin E Crooks, Gary Hon, John-Marc Chandonia, Steven E Brenner | Genome Res | 2004 | 15173120 | Yes |
1014 | 6383 | 2127.7 | 177.04 | 59.0 | Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. | F E Harrell, K L Lee, D B Mark | Stat Med | 1996 | 8668867 | No |
1015 | 2127 | 2127.0 | 39.92 | 39.9 | NK cell recognition. | Lewis L Lanier | Annu Rev Immunol | 2005 | 15771571 | No |
1016 | 2123 | 2123.0 | 51.04 | 51.0 | Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences. | Edward V Loftus | Gastroenterology | 2004 | 15168363 | Yes |
1017 | 2123 | 2123.0 | 60.01 | 60.0 | Infrared spectroscopy of proteins. | Andreas Barth | Biochim Biophys Acta | 2007 | 17692815 | No |
1018 | 6366 | 2122.0 | 145.83 | 48.6 | MOLMOL: a program for display and analysis of macromolecular structures. | R Koradi, M Billeter, K Wüthrich | J Mol Graph | 1996 | 8744573 | Yes |
1019 | 4242 | 2121.0 | 121.91 | 61.0 | Angiogenic factors. | J Folkman, M Klagsbrun | Science | 1987 | 2432664 | No |
1020 | 2120 | 2120.0 | 44.62 | 44.6 | Mammalian G1 cyclins. | C J Sherr | Cell | 1993 | 8513492 | No |
1021 | 2120 | 2120.0 | 52.49 | 52.5 | Using circular dichroism spectra to estimate protein secondary structure. | Norma J Greenfield | Nat Protoc | 2006 | 17406547 | Yes |
1022 | 4239 | 2119.5 | 80.53 | 40.3 | The fundamental role of epigenetic events in cancer. | Peter A Jones, Stephen B Baylin | Nat Rev Genet | 2002 | 12042769 | No |
1023 | 2119 | 2119.0 | 42.43 | 42.4 | Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. | Shimon Sakaguchi | Nat Immunol | 2005 | 15785760 | No |
1024 | 6354 | 2118.0 | 285.76 | 95.3 | Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test. | B N Ames, J Mccann, E Yamasaki | Mutat Res | 1975 | 768755 | Yes |
1025 | 2116 | 2116.0 | 35.69 | 35.7 | Methods for the quantitative estimation of N-acetylneuraminic acid and their application to hydrolysates of sialomucoids. | D Aminoff | Biochem J | 1961 | 13860975 | Yes |
1026 | 6347 | 2115.7 | 197.94 | 66.0 | Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire. | R L Spitzer, K Kroenke, J B Williams | JAMA | 1999 | 10568646 | Yes |
1027 | 2114 | 2114.0 | 47.74 | 47.7 | Comparison of the predicted and observed secondary structure of T4 phage lysozyme. | B W Matthews | Biochim Biophys Acta | 1975 | 1180967 | Yes |
1028 | 4228 | 2114.0 | 180.62 | 90.3 | The Health Belief Model: a decade later. | N K Janz, M H Becker | Health Educ Q | 1984 | 6392204 | No |
1029 | 2112 | 2112.0 | 63.97 | 64.0 | The unbiased estimation of number and sizes of arbitrary particles using the disector. | D C Sterio | J Microsc | 1984 | 6737468 | Yes |
1030 | 2112 | 2112.0 | 89.81 | 89.8 | What's in a name? Qualitative description revisited. | Margarete Sandelowski | Res Nurs Health | 2010 | 20014004 | Yes |
1031 | 6333 | 2111.0 | 119.28 | 39.8 | Control of regulatory T cell development by the transcription factor Foxp3. | Shohei Hori, Takashi Nomura, Shimon Sakaguchi | Science | 2003 | 12522256 | Yes |
1032 | 2108 | 2108.0 | 45.13 | 45.1 | Theta oscillations in the hippocampus. | György Buzsáki | Neuron | 2002 | 11832222 | No |
1033 | 4214 | 2107.0 | 106.68 | 53.3 | Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. | E Lander, L Kruglyak | Nat Genet | 1995 | 7581446 | Yes |
1034 | 2107 | 2107.0 | 42.96 | 43.0 | Role of angiogenesis in tumor growth and metastasis. | Judah Folkman | Semin Oncol | 2002 | 12516034 | No |
1035 | 6317 | 2105.7 | 160.05 | 53.4 | GUS fusions: beta-glucuronidase as a sensitive and versatile gene fusion marker in higher plants. | R A Jefferson, T A Kavanagh, M W Bevan | EMBO J | 1987 | 3327686 | Yes |
1036 | 2104 | 2104.0 | 54.34 | 54.3 | The physiology of glucagon-like peptide 1. | Jens Juul Holst | Physiol Rev | 2007 | 17928588 | No |
1037 | 12618 | 2103.0 | 281.79 | 47.0 | NMRPipe: a multidimensional spectral processing system based on UNIX pipes. | F Delaglio, S Grzesiek, G W Vuister, G Zhu, J Pfeifer, A Bax | J Biomol NMR | 1995 | 8520220 | Yes |
1038 | 4204 | 2102.0 | 133.93 | 67.0 | A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. | Gary J Bennett, Y-K Xie | Pain | 1988 | 2837713 | Yes |
1039 | 2101 | 2101.0 | 52.95 | 53.0 | Accurate description of van der Waals complexes by density functional theory including empirical corrections. | Stefan Grimme | J Comput Chem | 2004 | 15224390 | Yes |
1040 | 2101 | 2101.0 | 103.72 | 103.7 | Metazoan MicroRNAs. | David P Bartel | Cell | 2018 | 29570994 | No |
1041 | 2100 | 2100.0 | 61.46 | 61.5 | Hypoxia-inducible factors in physiology and medicine. | Gregg L Semenza | Cell | 2012 | 22304911 | No |
1042 | 2099 | 2099.0 | 49.64 | 49.6 | Patterns of amino acids near signal-sequence cleavage sites. | G von Heijne | Eur J Biochem | 1983 | 6852022 | Yes |
1043 | 2097 | 2097.0 | 38.2 | 38.2 | Chemiosmotic coupling in oxidative and photosynthetic phosphorylation. | P Mitchell | Biol Rev Camb Philos Soc | 1966 | 5329743 | No |
1044 | 4193 | 2096.5 | 82.27 | 41.1 | Network biology: understanding the cell's functional organization. | Albert-László Barabási, Zoltán N Oltvai | Nat Rev Genet | 2004 | 14735121 | No |
1045 | 2096 | 2096.0 | 112.76 | 112.8 | The assessment of clinical skills/competence/performance. | G E Miller | Acad Med | 1990 | 2400509 | Yes |
1046 | 2096 | 2096.0 | 90.57 | 90.6 | The Children's Depression, Inventory (CDI). | M Kovacs | Psychopharmacol Bull | 1985 | 4089116 | Yes |
1047 | 2095 | 2095.0 | 56.46 | 56.5 | The plasma lecithins:cholesterol acyltransferase reaction. | J A Glomset | J Lipid Res | 1968 | 4868699 | No |
1048 | 2092 | 2092.0 | 83.15 | 83.2 | A clinically based classification system for acute pancreatitis. Summary of the International Symposium on Acute Pancreatitis, Atlanta, Ga, September 11 through 13, 1992. | E L Bradley | Arch Surg | 1993 | 8489394 | No |
1049 | 4178 | 2089.0 | 82.29 | 41.1 | Smad-dependent and Smad-independent pathways in TGF-beta family signalling. | Rik Derynck, Ying E Zhang | Nature | 2003 | 14534577 | No |
1050 | 4177 | 2088.5 | 110.29 | 55.1 | The inflammasomes. | Kate Schroder, Jurg Tschopp | Cell | 2010 | 20303873 | No |
1051 | 2088 | 2088.0 | 90.3 | 90.3 | Method For Assay Of Intestinal Disaccharidases. | A Dahlqvist | Anal Biochem | 1964 | 14106916 | Yes |
1052 | 4173 | 2086.5 | 142.99 | 71.5 | Shifting the genomic gold standard for the prokaryotic species definition. | Michael Richter, Ramon Rosselló-Móra | Proc Natl Acad Sci U S A | 2009 | 19855009 | Yes |
1053 | 2085 | 2085.0 | 45.71 | 45.7 | Biology of natural killer cells. | G Trinchieri | Adv Immunol | 1989 | 2683611 | No |
1054 | 2084 | 2084.0 | 63.85 | 63.9 | Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. | Leonardo Pantoni | Lancet Neurol | 2010 | 20610345 | No |
1055 | 4160 | 2080.0 | 101.47 | 50.7 | Measuring the thickness of the human cerebral cortex from magnetic resonance images. | B Fischl, A M Dale | Proc Natl Acad Sci U S A | 2000 | 10984517 | Yes |
1056 | 4158 | 2079.0 | 108.84 | 54.4 | The heat-shock proteins. | S Lindquist, E A Craig | Annu Rev Genet | 1988 | 2853609 | No |
1057 | 2077 | 2077.0 | 103.1 | 103.1 | Abiotic Stress Signaling and Responses in Plants. | Jian-Kang Zhu | Cell | 2016 | 27716505 | No |
1058 | 6228 | 2076.0 | 128.07 | 42.7 | EMBOSS: the European Molecular Biology Open Software Suite. | P Rice, I Longden, A Bleasby | Trends Genet | 2000 | 10827456 | Yes |
1059 | 2075 | 2075.0 | 74.14 | 74.1 | International experiences with the Hospital Anxiety and Depression Scale--a review of validation data and clinical results. | C Herrmann | J Psychosom Res | 1997 | 9055211 | No |
1060 | 4146 | 2073.0 | 86.75 | 43.4 | A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation. | G Shaw, R Kamen | Cell | 1986 | 3488815 | Yes |
1061 | 4145 | 2072.5 | 100.53 | 50.3 | Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. | G G Glenner, C W Wong | Biochem Biophys Res Commun | 1984 | 6375662 | Yes |
1062 | 4140 | 2070.0 | 82.09 | 41.0 | Mammalian MAP kinase signalling cascades. | L Chang, M Karin | Nature | 2001 | 11242034 | No |
1063 | 6210 | 2070.0 | 146.57 | 48.9 | APE: Analyses of Phylogenetics and Evolution in R language. | Emmanuel Paradis, Julien Claude, Korbinian Strimmer | Bioinformatics | 2004 | 14734327 | Yes |
1064 | 2070 | 2070.0 | 50.21 | 50.2 | Dopamine, learning and motivation. | Roy A Wise | Nat Rev Neurosci | 2004 | 15152198 | No |
1065 | 2069 | 2069.0 | 45.3 | 45.3 | Defensins: antimicrobial peptides of innate immunity. | Tomas Ganz | Nat Rev Immunol | 2003 | 12949495 | No |
1066 | 2069 | 2069.0 | 38.0 | 38.0 | Enzymatic Basis For Active Transport Of Na+ And K+ Across Cell Membrane. | J C Skou | Physiol Rev | 1965 | 14337569 | No |
1067 | 4137 | 2068.5 | 36.42 | 18.2 | Genetic regulatory mechanisms in the synthesis of proteins. | F Jacob, J Monod | J Mol Biol | 1961 | 13718526 | Yes |
1068 | 2068 | 2068.0 | 54.05 | 54.0 | Selection Of Hybrids From Matings Of Fibroblasts In Vitro And Their Presumed Recombinants. | J W Littlefield | Science | 1964 | 14168277 | Yes |
1069 | 2067 | 2067.0 | 59.5 | 59.5 | ATP-regulated K+ channels in cardiac muscle. | A Noma | Nature | 1983 | 6310409 | Yes |
1070 | 2066 | 2066.0 | 42.49 | 42.5 | G1 events and regulation of cell proliferation. | A B Pardee | Science | 1989 | 2683075 | No |
1071 | 2066 | 2066.0 | 53.23 | 53.2 | The heme oxygenase system: a regulator of second messenger gases. | M D Maines | Annu Rev Pharmacol Toxicol | 1997 | 9131263 | No |
1072 | 4130 | 2065.0 | 81.45 | 40.7 | Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. | M Gossen, H Bujard | Proc Natl Acad Sci U S A | 1992 | 1319065 | Yes |
1073 | 8255 | 2063.8 | 303.28 | 75.8 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | J Clin Epidemiol | 2009 | 19631508 | No |
1074 | 2063 | 2063.0 | 50.48 | 50.5 | Drug-like properties and the causes of poor solubility and poor permeability. | C A Lipinski | J Pharmacol Toxicol Methods | 2000 | 11274893 | No |
1075 | 4119 | 2059.5 | 0.0 | 0.0 | Plaque formation and isolation of pure lines with poliomyelitis viruses. | R Dulbecco, M Vogt | J Exp Med | 1954 | 13130792 | Yes |
1076 | 2058 | 2058.0 | 48.46 | 48.5 | Interleukin-2: inception, impact, and implications. | K A Smith | Science | 1988 | 3131876 | No |
1077 | 2056 | 2056.0 | 68.71 | 68.7 | Purinergic nerves. | G Burnstock | Pharmacol Rev | 1972 | 4404211 | No |
1078 | 2053 | 2053.0 | 47.94 | 47.9 | Metabolomics--the link between genotypes and phenotypes. | Oliver Fiehn | Plant Mol Biol | 2002 | 11860207 | No |
1079 | 2052 | 2052.0 | 67.04 | 67.0 | Optimal caliper widths for propensity-score matching when estimating differences in means and differences in proportions in observational studies. | Peter C Austin | Pharm Stat | 2011 | 20925139 | Yes |
1080 | 4101 | 2050.5 | 110.99 | 55.5 | New perspectives in cell adhesion: RGD and integrins. | E Ruoslahti, M D Pierschbacher | Science | 1987 | 2821619 | No |
1081 | 4095 | 2047.5 | 80.6 | 40.3 | Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. | Rudolf Jaenisch, Adrian Bird | Nat Genet | 2003 | 12610534 | No |
1082 | 2047 | 2047.0 | 53.17 | 53.2 | Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. | Gökhan S Hotamisligil | Cell | 2010 | 20303879 | No |
1083 | 2046 | 2046.0 | 13.46 | 13.5 | The kinetics of enzyme-catalyzed reactions with two or more substrates or products. I. Nomenclature and rate equations. | W W Cleland | Biochim Biophys Acta | 1963 | 14021667 | Yes |
1084 | 4084 | 2042.0 | 183.47 | 91.7 | Stages and processes of self-change of smoking: toward an integrative model of change. | J O Prochaska, C C DiClemente | J Consult Clin Psychol | 1983 | 6863699 | Yes |
1085 | 4083 | 2041.5 | 100.69 | 50.3 | Cutaneous wound healing. | A J Singer, R A Clark | N Engl J Med | 1999 | 10471461 | No |
1086 | 4081 | 2040.5 | 173.85 | 86.9 | The MOS social support survey. | C D Sherbourne, A L Stewart | Soc Sci Med | 1991 | 2035047 | Yes |
1087 | 2040 | 2040.0 | 41.31 | 41.3 | Metastasis to bone: causes, consequences and therapeutic opportunities. | Gregory R Mundy | Nat Rev Cancer | 2002 | 12154351 | No |
1088 | 2039 | 2039.0 | 51.11 | 51.1 | Determination and analysis of urea and guanidine hydrochloride denaturation curves. | C N Pace | Methods Enzymol | 1986 | 3773761 | Yes |
1089 | 2039 | 2039.0 | 58.36 | 58.4 | Medscape's response to the Institute of Medicine Report: Crossing the quality chasm: a new health system for the 21st century. | M Leavitt | MedGenMed | 2001 | 11549951 | No |
1090 | 6109 | 2036.3 | 182.36 | 60.8 | Arlequin (version 3.0): an integrated software package for population genetics data analysis. | Laurent Excoffier, Guillaume Laval, Stefan Schneider | Evol Bioinform Online | 2007 | 19325852 | Yes |
1091 | 2036 | 2036.0 | 39.59 | 39.6 | Signalling pathways of the TNF superfamily: a double-edged sword. | Bharat B Aggarwal | Nat Rev Immunol | 2003 | 12949498 | No |
1092 | 4072 | 2036.0 | 112.92 | 56.5 | Autophagy: renovation of cells and tissues. | Noboru Mizushima, Masaaki Komatsu | Cell | 2011 | 22078875 | No |
1093 | 6106 | 2035.3 | 201.01 | 67.0 | Parallel organization of functionally segregated circuits linking basal ganglia and cortex. | G E Alexander, M R DeLong, P L Strick | Annu Rev Neurosci | 1986 | 3085570 | No |
1094 | 4070 | 2035.0 | 98.54 | 49.3 | Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. | P Liang, A B Pardee | Science | 1992 | 1354393 | Yes |
1095 | 2035 | 2035.0 | 72.49 | 72.5 | Determination of glutathione and glutathione disulfide in biological samples. | M E Anderson | Methods Enzymol | 1985 | 4088074 | Yes |
1096 | 2035 | 2035.0 | 47.74 | 47.7 | Calcium signaling. | D E Clapham | Cell | 1995 | 7834745 | No |
1097 | 2035 | 2035.0 | 50.46 | 50.5 | Mechanisms of hepatic fibrogenesis. | Scott L Friedman | Gastroenterology | 2008 | 18471545 | No |
1098 | 8138 | 2034.5 | 174.95 | 43.7 | MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform. | Kazutaka Katoh, Kazuharu Misawa, Kei-ichi Kuma, Takashi Miyata | Nucleic Acids Res | 2002 | 12136088 | Yes |
1099 | 4067 | 2033.5 | 124.68 | 62.3 | Macrophage plasticity and polarization: in vivo veritas. | Antonio Sica, Alberto Mantovani | J Clin Invest | 2012 | 22378047 | No |
1100 | 8133 | 2033.2 | 266.89 | 66.7 | Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. | A J Hughes, S E Daniel, L Kilford, A J Lees | J Neurol Neurosurg Psychiatry | 1992 | 1564476 | Yes |
1101 | 2033 | 2033.0 | 41.94 | 41.9 | Molecular bases for circadian clocks. | J C Dunlap | Cell | 1999 | 9988221 | No |
1102 | 2032 | 2032.0 | 46.7 | 46.7 | Follicular helper CD4 T cells (TFH). | Shane Crotty | Annu Rev Immunol | 2011 | 21314428 | No |
1103 | 2031 | 2031.0 | 56.51 | 56.5 | Estimating causal effects from large data sets using propensity scores. | D B Rubin | Ann Intern Med | 1997 | 9382394 | No |
1104 | 4057 | 2028.5 | 129.69 | 64.8 | Polymyositis and dermatomyositis (first of two parts). | A Bohan, J B Peter | N Engl J Med | 1975 | 1090839 | No |
1105 | 2028 | 2028.0 | 44.39 | 44.4 | Structural design and molecular evolution of a cytokine receptor superfamily. | J F Bazan | Proc Natl Acad Sci U S A | 1990 | 2169613 | Yes |
1106 | 2028 | 2028.0 | 64.28 | 64.3 | Health consequences of intimate partner violence. | Jacquelyn C Campbell | Lancet | 2002 | 11965295 | No |
1107 | 2024 | 2024.0 | 62.85 | 62.9 | Ethical authorship and publishing. | Andrew J S Coats | Int J Cardiol | 2009 | 19046787 | No |
1108 | 4048 | 2024.0 | 118.32 | 59.2 | Wnt/β-catenin signaling and disease. | Hans Clevers, Roel Nusse | Cell | 2012 | 22682243 | No |
1109 | 4045 | 2022.5 | 94.74 | 47.4 | Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. | B A Reynolds, S Weiss | Science | 1992 | 1553558 | Yes |
1110 | 2021 | 2021.0 | 52.54 | 52.5 | Analysis of bacteriophage T7 early RNAs and proteins on slab gels. | F W Studier | J Mol Biol | 1973 | 4760132 | Yes |
1111 | 2020 | 2020.0 | 58.46 | 58.5 | Protein oxidation and aging. | E R Stadtman | Science | 1992 | 1355616 | No |
1112 | 2020 | 2020.0 | 0.0 | 0.0 | Antigen-antibody reactions in gels. | O Ouchterlony | Acta Pathol Microbiol Scand | 1949 | 18143039 | Yes |
1113 | 4031 | 2015.5 | 79.35 | 39.7 | The Wnt signaling pathway in development and disease. | Catriona Y Logan, Roel Nusse | Annu Rev Cell Dev Biol | 2004 | 15473860 | No |
1114 | 12085 | 2014.2 | 379.63 | 63.3 | Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. | Jacques Ferlay, Hai-Rim Shin, Freddie Bray, David Forman, Colin Mathers, Donald Maxwell Parkin | Int J Cancer | 2010 | 21351269 | Yes |
1115 | 6039 | 2013.0 | 186.46 | 62.2 | Universal solvation model based on solute electron density and on a continuum model of the solvent defined by the bulk dielectric constant and atomic surface tensions. | Aleksandr V Marenich, Christopher J Cramer, Donald G Truhlar | J Phys Chem B | 2009 | 19366259 | Yes |
1116 | 6036 | 2012.0 | 227.18 | 75.7 | Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA. | G Muyzer, E C de Waal, A G Uitterlinden | Appl Environ Microbiol | 1993 | 7683183 | Yes |
1117 | 2012 | 2012.0 | 39.0 | 39.0 | CpG motifs in bacterial DNA and their immune effects. | Arthur M Krieg | Annu Rev Immunol | 2002 | 11861616 | No |
1118 | 6031 | 2010.3 | 193.67 | 64.6 | Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. | C Lord, M Rutter, A Le Couteur | J Autism Dev Disord | 1994 | 7814313 | Yes |
1119 | 2009 | 2009.0 | 35.08 | 35.1 | ATM and related protein kinases: safeguarding genome integrity. | Yosef Shiloh | Nat Rev Cancer | 2003 | 12612651 | No |
1120 | 10045 | 2009.0 | 235.15 | 47.0 | Development and testing of a general amber force field. | Junmei Wang, Romain M Wolf, James W Caldwell, Peter A Kollman, David A Case | J Comput Chem | 2004 | 15116359 | Yes |
1121 | 2007 | 2007.0 | 41.63 | 41.6 | XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density. | D E McRee | J Struct Biol | 1999 | 10222271 | Yes |
1122 | 2003 | 2003.0 | 46.92 | 46.9 | DAMPs, PAMPs and alarmins: all we need to know about danger. | Marco E Bianchi | J Leukoc Biol | 2007 | 17032697 | No |
1123 | 4003 | 2001.5 | 0.0 | 0.0 | A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. | R F Beers, I W Sizer | J Biol Chem | 1952 | 14938361 | Yes |
1124 | 2000 | 2000.0 | 78.36 | 78.4 | Perception of risk. | P Slovic | Science | 1987 | 3563507 | Yes |
1125 | 2000 | 2000.0 | 47.3 | 47.3 | Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. | Scott L Friedman | Physiol Rev | 2008 | 18195085 | No |
1126 | 3998 | 1999.0 | 173.25 | 86.6 | The Brief Symptom Inventory: an introductory report. | L R Derogatis, N Melisaratos | Psychol Med | 1983 | 6622612 | Yes |
1127 | 3997 | 1998.5 | 103.32 | 51.7 | Building better batteries. | M Armand, J-M Tarascon | Nature | 2008 | 18256660 | No |
1128 | 7992 | 1998.0 | 380.26 | 95.1 | The Satisfaction With Life Scale. | E Diener, R A Emmons, R J Larsen, S Griffin | J Pers Assess | 1985 | 16367493 | Yes |
1129 | 3996 | 1998.0 | 107.62 | 53.8 | The unfolded protein response: from stress pathway to homeostatic regulation. | Peter Walter, David Ron | Science | 2011 | 22116877 | No |
1130 | 3994 | 1997.0 | 96.64 | 48.3 | Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions. | M Nei, T Gojobori | Mol Biol Evol | 1986 | 3444411 | Yes |
1131 | 1996 | 1996.0 | 42.49 | 42.5 | The fractionation of high-molecular-weight ribonucleic acid by polyacrylamide-gel electrophoresis. | U E Loening | Biochem J | 1967 | 5339944 | Yes |
1132 | 1994 | 1994.0 | 36.53 | 36.5 | In situ hybridization: an improved whole-mount method for Xenopus embryos. | R M Harland | Methods Cell Biol | 1991 | 1811161 | Yes |
1133 | 1991 | 1991.0 | 50.69 | 50.7 | Flow-mediated endothelial mechanotransduction. | P F Davies | Physiol Rev | 1995 | 7624393 | No |
1134 | 1991 | 1991.0 | 40.97 | 41.0 | Mechanisms of intracellular protein transport. | J E Rothman | Nature | 1994 | 7969419 | No |
1135 | 1990 | 1990.0 | 82.78 | 82.8 | A rating scale for drug-induced akathisia. | T R Barnes | Br J Psychiatry | 1989 | 2574607 | Yes |
1136 | 5966 | 1988.7 | 172.98 | 57.7 | GSVA: gene set variation analysis for microarray and RNA-seq data. | Sonja Hänzelmann, Robert Castelo, Justin Guinney | BMC Bioinformatics | 2013 | 23323831 | Yes |
1137 | 3974 | 1987.0 | 86.06 | 43.0 | The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. | A J Ridley, A Hall | Cell | 1992 | 1643657 | Yes |
1138 | 3972 | 1986.0 | 143.66 | 71.8 | Deciphering key features in protein structures with the new ENDscript server. | Xavier Robert, Patrice Gouet | Nucleic Acids Res | 2014 | 24753421 | Yes |
1139 | 3970 | 1985.0 | 85.21 | 42.6 | Lessons from hereditary colorectal cancer. | K W Kinzler, B Vogelstein | Cell | 1996 | 8861899 | No |
1140 | 7937 | 1984.2 | 297.57 | 74.4 | The Fagerström Test for Nicotine Dependence: a revision of the Fagerström Tolerance Questionnaire. | T F Heatherton, L T Kozlowski, R C Frecker, K O Fagerström | Br J Addict | 1991 | 1932883 | Yes |
1141 | 1984 | 1984.0 | 53.02 | 53.0 | Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis. | J Folkman | N Engl J Med | 1995 | 7491141 | No |
1142 | 1982 | 1982.0 | 95.17 | 95.2 | Performance-oriented assessment of mobility problems in elderly patients. | M E Tinetti | J Am Geriatr Soc | 1986 | 3944402 | Yes |
1143 | 1982 | 1982.0 | 72.21 | 72.2 | UCLA Loneliness Scale (Version 3): reliability, validity, and factor structure. | D W Russell | J Pers Assess | 1996 | 8576833 | Yes |
1144 | 1982 | 1982.0 | 39.16 | 39.2 | DNA topoisomerases: structure, function, and mechanism. | J J Champoux | Annu Rev Biochem | 2001 | 11395412 | No |
1145 | 1982 | 1982.0 | 48.25 | 48.2 | Interfaces and the driving force of hydrophobic assembly. | David Chandler | Nature | 2005 | 16193038 | No |
1146 | 1981 | 1981.0 | 54.43 | 54.4 | The biology of interleukin-6. | T Kishimoto | Blood | 1989 | 2473791 | No |
1147 | 1980 | 1980.0 | 38.24 | 38.2 | Antiviral actions of interferons. | C E Samuel | Clin Microbiol Rev | 2001 | 11585785 | No |
1148 | 1980 | 1980.0 | 55.27 | 55.3 | Japanese Classification of Gastric Carcinoma - 2nd English Edition - | Japanese Gastric Cancer Association | Gastric Cancer | 1998 | 11957040 | Yes |
1149 | 1977 | 1977.0 | 65.88 | 65.9 | The use of a plus-maze to measure anxiety in the mouse. | R G Lister | Psychopharmacology (Berl) | 1987 | 3110839 | Yes |
1150 | 1977 | 1977.0 | 20.58 | 20.6 | Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? | J V Neel | Am J Hum Genet | 1962 | 13937884 | Yes |
1151 | 3944 | 1972.0 | 97.68 | 48.8 | Leptin and the regulation of body weight in mammals. | J M Friedman, J L Halaas | Nature | 1998 | 9796811 | No |
1152 | 3939 | 1969.5 | 89.84 | 44.9 | The acute respiratory distress syndrome. | L B Ware, M A Matthay | N Engl J Med | 2000 | 10793167 | No |
1153 | 3936 | 1968.0 | 90.14 | 45.1 | Base-calling of automated sequencer traces using phred. II. Error probabilities. | B Ewing, P Green | Genome Res | 1998 | 9521922 | Yes |
1154 | 1968 | 1968.0 | 48.59 | 48.6 | Negative refraction makes a perfect lens | J B Pendry | Phys Rev Lett | 2000 | 11041972 | Yes |
1155 | 13771 | 1967.3 | 304.03 | 43.4 | Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. | Jo Vandesompele, Katleen De Preter, Filip Pattyn, Bruce Poppe, Nadine Van Roy, Anne De Paepe, Frank Speleman | Genome Biol | 2002 | 12184808 | Yes |
1156 | 1967 | 1967.0 | 58.07 | 58.1 | Intracellular calcium homeostasis. | E Carafoli | Annu Rev Biochem | 1987 | 3304139 | No |
1157 | 1967 | 1967.0 | 50.36 | 50.4 | What is cognitive reserve? Theory and research application of the reserve concept. | Yaakov Stern | J Int Neuropsychol Soc | 2002 | 11939702 | No |
1158 | 1967 | 1967.0 | 41.46 | 41.5 | TRP channels as cellular sensors. | David E Clapham | Nature | 2003 | 14654832 | No |
1159 | 1966 | 1966.0 | 41.61 | 41.6 | Developmental regulation of the growth plate. | Henry M Kronenberg | Nature | 2003 | 12748651 | No |
1160 | 1964 | 1964.0 | 86.31 | 86.3 | A modified card sorting test sensitive to frontal lobe defects. | H E Nelson | Cortex | 1976 | 1009768 | Yes |
1161 | 1964 | 1964.0 | 35.06 | 35.1 | Signaling--2000 and beyond. | T Hunter | Cell | 2000 | 10647936 | No |
1162 | 1964 | 1964.0 | 58.76 | 58.8 | Global epidemiology of oral and oropharyngeal cancer. | Saman Warnakulasuriya | Oral Oncol | 2009 | 18804401 | No |
1163 | 3921 | 1960.5 | 96.65 | 48.3 | Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. | P J Barnes, M Karin | N Engl J Med | 1997 | 9091804 | No |
1164 | 3918 | 1959.0 | 107.42 | 53.7 | Insulin-like growth factors and their binding proteins: biological actions. | J I Jones, D R Clemmons | Endocr Rev | 1995 | 7758431 | No |
1165 | 1959 | 1959.0 | 55.02 | 55.0 | Flavonoids as antioxidants. | P G Pietta | J Nat Prod | 2000 | 10924197 | No |
1166 | 1959 | 1959.0 | 42.74 | 42.7 | Neutrophils and immunity: challenges and opportunities. | Carl Nathan | Nat Rev Immunol | 2006 | 16498448 | No |
1167 | 3914 | 1957.0 | 74.56 | 37.3 | SIFT: Predicting amino acid changes that affect protein function. | Pauline C Ng, Steven Henikoff | Nucleic Acids Res | 2003 | 12824425 | Yes |
1168 | 3912 | 1956.0 | 65.51 | 32.8 | Periodate-lysine-paraformaldehyde fixative. A new fixation for immunoelectron microscopy. | I W McLean, P K Nakane | J Histochem Cytochem | 1974 | 4374474 | Yes |
1169 | 1956 | 1956.0 | 0.0 | 0.0 | Crystalline Soybean Trypsin Inhibitor : Ii. General Properties. | M Kunitz | J Gen Physiol | 1947 | 19873496 | Yes |
1170 | 1954 | 1954.0 | 38.11 | 38.1 | Approaching the asymptote? Evolution and revolution in immunology. | C A Janeway | Cold Spring Harb Symp Quant Biol | 1989 | 2700931 | No |
1171 | 1954 | 1954.0 | 90.76 | 90.8 | The brain's default mode network. | Marcus E Raichle | Annu Rev Neurosci | 2015 | 25938726 | No |
1172 | 5861 | 1953.7 | 120.76 | 40.3 | Rapid and efficient site-specific mutagenesis without phenotypic selection. | T A Kunkel, J D Roberts, R A Zakour | Methods Enzymol | 1987 | 3323813 | Yes |
1173 | 3905 | 1952.5 | 123.41 | 61.7 | Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid. | A C Chang, S N Cohen | J Bacteriol | 1978 | 149110 | Yes |
1174 | 1951 | 1951.0 | 0.0 | 0.0 | The adsorption of proteins on erythrocytes treated with tannic acid and subsequent hemagglutination by antiprotein sera. | S V Boyden | J Exp Med | 1951 | 14803635 | Yes |
1175 | 3901 | 1950.5 | 109.11 | 54.6 | Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. | B J Marshall, J R Warren | Lancet | 1984 | 6145023 | Yes |
1176 | 1950 | 1950.0 | 79.5 | 79.5 | Specific pharmacology of calcium in myocardium, cardiac pacemakers, and vascular smooth muscle. | A Fleckenstein | Annu Rev Pharmacol Toxicol | 1977 | 326161 | No |
1177 | 1950 | 1950.0 | 58.89 | 58.9 | Loss, trauma, and human resilience: have we underestimated the human capacity to thrive after extremely aversive events? | George A Bonanno | Am Psychol | 2004 | 14736317 | No |
1178 | 1949 | 1949.0 | 60.28 | 60.3 | Fluorographic detection of radioactivity in polyacrylamide gels with the water-soluble fluor, sodium salicylate. | J P Chamberlain | Anal Biochem | 1979 | 543547 | Yes |
1179 | 1948 | 1948.0 | 0.0 | 0.0 | On estimating the relation between blood group and disease. | B Woolf | Ann Hum Genet | 1955 | 14388528 | Yes |
1180 | 7789 | 1947.2 | 231.97 | 58.0 | Antibiotic susceptibility testing by a standardized single disk method. | A W Bauer, W M Kirby, J C Sherris, M Turck | Am J Clin Pathol | 1966 | 5325707 | Yes |
1181 | 1947 | 1947.0 | 69.27 | 69.3 | The emerging role of lncRNAs in cancer. | Maite Huarte | Nat Med | 2015 | 26540387 | No |
1182 | 1946 | 1946.0 | 64.2 | 64.2 | Intermediate filaments as mechanical integrators of cellular space. | E Lazarides | Nature | 1980 | 7188712 | Yes |
1183 | 1946 | 1946.0 | 0.0 | 0.0 | Influences of glucose loading and of injected insulin on hepatic glucose output. | R Steele | Ann N Y Acad Sci | 1959 | 13833973 | Yes |
1184 | 1946 | 1946.0 | 38.64 | 38.6 | DNA methylation and human disease. | Keith D Robertson | Nat Rev Genet | 2005 | 16136652 | No |
1185 | 7783 | 1945.8 | 323.66 | 80.9 | jModelTest 2: more models, new heuristics and parallel computing. | Diego Darriba, Guillermo L Taboada, Ramón Doallo, David Posada | Nat Methods | 2012 | 22847109 | Yes |
1186 | 5833 | 1944.3 | 189.49 | 63.2 | AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. | P G Reeves, F H Nielsen, G C Fahey | J Nutr | 1993 | 8229312 | No |
1187 | 1943 | 1943.0 | 40.97 | 41.0 | The immunopathogenesis of sepsis. | Jonathan Cohen | Nature | 2002 | 12490963 | No |
1188 | 1943 | 1943.0 | 140.85 | 140.8 | Obesity: global epidemiology and pathogenesis. | Matthias Blüher | Nat Rev Endocrinol | 2019 | 30814686 | No |
1189 | 1942 | 1942.0 | 37.73 | 37.7 | Systems biology: a brief overview. | Hiroaki Kitano | Science | 2002 | 11872829 | No |
1190 | 1941 | 1941.0 | 45.77 | 45.8 | Thickness, cross-sectional areas and depth of invasion in the prognosis of cutaneous melanoma. | A Breslow | Ann Surg | 1970 | 5477666 | Yes |
1191 | 31046 | 1940.4 | 1012.95 | 63.3 | Fiji: an open-source platform for biological-image analysis. | Johannes Schindelin, Ignacio Arganda-Carreras, Erwin Frise, Verena Kaynig, Mark Longair, Tobias Pietzsch, Stephan Preibisch, Curtis Rueden, Stephan Saalfeld, Benjamin Schmid, Jean-Yves Tinevez, Daniel James White, Volker Hartenstein, Kevin Eliceiri, Pavel Tomancak, Albert Cardona | Nat Methods | 2012 | 22743772 | Yes |
1192 | 1940 | 1940.0 | 53.5 | 53.5 | Trail Making Test A and B: normative data stratified by age and education. | Tom N Tombaugh | Arch Clin Neuropsychol | 2004 | 15010086 | Yes |
1193 | 3877 | 1938.5 | 94.23 | 47.1 | Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. | J G Rheinwald, H Green | Cell | 1975 | 1052771 | Yes |
1194 | 13568 | 1938.3 | 311.19 | 44.5 | Induction of pluripotent stem cells from adult human fibroblasts by defined factors. | Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda, Shinya Yamanaka | Cell | 2007 | 18035408 | Yes |
1195 | 1937 | 1937.0 | 55.29 | 55.3 | Excitotoxic cell death. | D W Choi | J Neurobiol | 1992 | 1361523 | No |
1196 | 1936 | 1936.0 | 39.05 | 39.0 | The complex language of chromatin regulation during transcription. | Shelley L Berger | Nature | 2007 | 17522673 | No |
1197 | 3871 | 1935.5 | 132.59 | 66.3 | Preparation Of Fatty Acid Methyl Esters And Dimethylacetals From Lipids With Boron Fluoride--Methanol. | W R Morrison, L M Smith | J Lipid Res | 1964 | 14221106 | Yes |
1198 | 7741 | 1935.2 | 189.83 | 47.5 | Cancer-related inflammation. | Alberto Mantovani, Paola Allavena, Antonio Sica, Frances Balkwill | Nature | 2008 | 18650914 | No |
1199 | 1935 | 1935.0 | 40.37 | 40.4 | A cell culture model for T lymphocyte clonal anergy. | R H Schwartz | Science | 1990 | 2113314 | Yes |
1200 | 5805 | 1935.0 | 175.83 | 58.6 | Estimating the mean and variance from the median, range, and the size of a sample. | Stela Pudar Hozo, Benjamin Djulbegovic, Iztok Hozo | BMC Med Res Methodol | 2005 | 15840177 | Yes |
1201 | 1935 | 1935.0 | 45.47 | 45.5 | The global health burden of infection-associated cancers in the year 2002. | Donald Maxwell Parkin | Int J Cancer | 2006 | 16404738 | Yes |
1202 | 5803 | 1934.3 | 107.47 | 35.8 | Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. | Jason D Fontenot, Marc A Gavin, Alexander Y Rudensky | Nat Immunol | 2003 | 12612578 | Yes |
1203 | 1934 | 1934.0 | 57.39 | 57.4 | Calbindin D-28k and parvalbumin in the rat nervous system. | M R Celio | Neuroscience | 1990 | 2199841 | Yes |
1204 | 1933 | 1933.0 | 61.23 | 61.2 | Calculation of substrate oxidation rates in vivo from gaseous exchange. | K N Frayn | J Appl Physiol Respir Environ Exerc Physiol | 1983 | 6618956 | Yes |
1205 | 1932 | 1932.0 | 60.84 | 60.8 | Sick individuals and sick populations. | G Rose | Int J Epidemiol | 1985 | 3872850 | Yes |
1206 | 1932 | 1932.0 | 44.66 | 44.7 | Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. | B L Wajchenberg | Endocr Rev | 2000 | 11133069 | No |
1207 | 1932 | 1932.0 | 0.0 | 0.0 | On respiratory impairment in cancer cells. | O Warburg | Science | 1956 | 13351639 | Yes |
1208 | 3864 | 1932.0 | 87.97 | 44.0 | Liver fibrosis. | Ramón Bataller, David A Brenner | J Clin Invest | 2005 | 15690074 | No |
1209 | 3864 | 1932.0 | 114.48 | 57.2 | Oncology meets immunology: the cancer-immunity cycle. | Daniel S Chen, Ira Mellman | Immunity | 2013 | 23890059 | No |
1210 | 1931 | 1931.0 | 39.75 | 39.8 | Thrombin signalling and protease-activated receptors. | S R Coughlin | Nature | 2000 | 11001069 | No |
1211 | 1931 | 1931.0 | 62.62 | 62.6 | Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. | Sergio Pecorelli | Int J Gynaecol Obstet | 2009 | 19367689 | No |
1212 | 3860 | 1930.0 | 102.89 | 51.4 | Inositol phosphates and cell signalling. | M J Berridge, R F Irvine | Nature | 1989 | 2550825 | No |
1213 | 3859 | 1929.5 | 85.18 | 42.6 | Issues and challenges facing rechargeable lithium batteries. | J M Tarascon, M Armand | Nature | 2001 | 11713543 | Yes |
1214 | 1929 | 1929.0 | 50.47 | 50.5 | DNA topoisomerase poisons as antitumor drugs. | L F Liu | Annu Rev Biochem | 1989 | 2549853 | No |
1215 | 1929 | 1929.0 | 42.92 | 42.9 | Signal sequences. The limits of variation. | G von Heijne | J Mol Biol | 1985 | 4032478 | Yes |
1216 | 1926 | 1926.0 | 60.69 | 60.7 | Epidemiological features of chronic low-back pain. | G B Andersson | Lancet | 1999 | 10470716 | No |
1217 | 3851 | 1925.5 | 86.1 | 43.0 | The DNA-damage response in human biology and disease. | Stephen P Jackson, Jiri Bartek | Nature | 2009 | 19847258 | No |
1218 | 3849 | 1924.5 | 94.89 | 47.4 | The endophenotype concept in psychiatry: etymology and strategic intentions. | Irving I Gottesman, Todd D Gould | Am J Psychiatry | 2003 | 12668349 | No |
1219 | 3847 | 1923.5 | 123.62 | 61.8 | Oxygen toxicity, oxygen radicals, transition metals and disease. | B Halliwell, J M Gutteridge | Biochem J | 1984 | 6326753 | No |
1220 | 1923 | 1923.0 | 33.86 | 33.9 | Mechanisms of alternative pre-messenger RNA splicing. | Douglas L Black | Annu Rev Biochem | 2003 | 12626338 | No |
1221 | 1922 | 1922.0 | 46.94 | 46.9 | DNA topoisomerases. | J C Wang | Annu Rev Biochem | 1985 | 2992360 | No |
1222 | 1922 | 1922.0 | 52.65 | 52.6 | Determination of minimum inhibitory concentrations. | J M Andrews | J Antimicrob Chemother | 2001 | 11420333 | Yes |
1223 | 3842 | 1921.0 | 73.67 | 36.8 | Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. | M Karin, Y Ben-Neriah | Annu Rev Immunol | 2000 | 10837071 | No |
1224 | 1920 | 1920.0 | 38.98 | 39.0 | The expanding role of mitochondria in apoptosis. | X Wang | Genes Dev | 2001 | 11711427 | No |
1225 | 1919 | 1919.0 | 46.54 | 46.5 | Thioredoxin. | A Holmgren | Annu Rev Biochem | 1985 | 3896121 | No |
1226 | 1917 | 1917.0 | 82.94 | 82.9 | Brain dopamine receptors. | P Seeman | Pharmacol Rev | 1980 | 6117090 | No |
1227 | 1916 | 1916.0 | 33.85 | 33.9 | The regulation of E2F by pRB-family proteins. | N Dyson | Genes Dev | 1998 | 9694791 | No |
1228 | 1914 | 1914.0 | 45.34 | 45.3 | The dawning era of polymer therapeutics. | Ruth Duncan | Nat Rev Drug Discov | 2003 | 12750738 | No |
1229 | 7653 | 1913.2 | 188.69 | 47.2 | p53 mutations in human cancers. | M Hollstein, D Sidransky, B Vogelstein, C C Harris | Science | 1991 | 1905840 | No |
1230 | 1913 | 1913.0 | 36.58 | 36.6 | Notch signalling: a simple pathway becomes complex. | Sarah J Bray | Nat Rev Mol Cell Biol | 2006 | 16921404 | No |
1231 | 3825 | 1912.5 | 128.04 | 64.0 | Mathematical model for studying genetic variation in terms of restriction endonucleases. | M Nei, W H Li | Proc Natl Acad Sci U S A | 1979 | 291943 | Yes |
1232 | 1912 | 1912.0 | 40.83 | 40.8 | The etiology of chondromalacia patellae. | R E Outerbridge | J Bone Joint Surg Br | 1961 | 14038135 | Yes |
1233 | 3823 | 1911.5 | 0.0 | 0.0 | Acetylornithinase of Escherichia coli: partial purification and some properties. | H J Vogel, D M Bonner | J Biol Chem | 1956 | 13278318 | Yes |
1234 | 1911 | 1911.0 | 42.88 | 42.9 | High-speed scanning in human memory. | S Sternberg | Science | 1966 | 5939936 | Yes |
1235 | 1911 | 1911.0 | 56.12 | 56.1 | Inhibited spontaneous emission in solid-state physics and electronics. | E Yablonovitch | Phys Rev Lett | 1987 | 10034639 | Yes |
1236 | 1911 | 1911.0 | 53.93 | 53.9 | Introduction and General Overview of Cyclodextrin Chemistry. | József Szejtli | Chem Rev | 1998 | 11848947 | Yes |
1237 | 7642 | 1910.5 | 297.81 | 74.5 | A simple technique for quantitation of low levels of DNA damage in individual cells. | N P Singh, M T McCoy, R R Tice, E L Schneider | Exp Cell Res | 1988 | 3345800 | Yes |
1238 | 1910 | 1910.0 | 63.01 | 63.0 | Physiological actions of taurine. | R J Huxtable | Physiol Rev | 1992 | 1731369 | No |
1239 | 1910 | 1910.0 | 59.82 | 59.8 | A new automated colorimetric method for measuring total oxidant status. | Ozcan Erel | Clin Biochem | 2005 | 16214125 | Yes |
1240 | 1908 | 1908.0 | 39.16 | 39.2 | Mechanisms of cancer drug resistance. | Michael M Gottesman | Annu Rev Med | 2002 | 11818492 | No |
1241 | 5718 | 1906.0 | 187.74 | 62.6 | Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction data. | L Excoffier, P E Smouse, J M Quattro | Genetics | 1992 | 1644282 | Yes |
1242 | 1906 | 1906.0 | 46.17 | 46.2 | Cancer chemoprevention with dietary phytochemicals. | Young-Joon Surh | Nat Rev Cancer | 2003 | 14570043 | No |
1243 | 1906 | 1906.0 | 61.01 | 61.0 | Grounded cognition. | Lawrence W Barsalou | Annu Rev Psychol | 2008 | 17705682 | No |
1244 | 3811 | 1905.5 | 119.29 | 59.6 | Efficient pseudopotentials for plane-wave calculations. | N Troullier, J L Martins | Phys Rev B Condens Matter | 1991 | 9997467 | Yes |
1245 | 3810 | 1905.0 | 98.08 | 49.0 | Probing Single Molecules and Single Nanoparticles by Surface-Enhanced Raman Scattering | S Nie, S R Emory | Science | 1997 | 9027306 | Yes |
1246 | 1905 | 1905.0 | 41.37 | 41.4 | A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics. | J SantaLucia | Proc Natl Acad Sci U S A | 1998 | 9465037 | Yes |
1247 | 1905 | 1905.0 | 49.03 | 49.0 | Dengue and dengue hemorrhagic fever. | D J Gubler | Clin Microbiol Rev | 1998 | 9665979 | No |
1248 | 3809 | 1904.5 | 88.11 | 44.1 | PRODRG: a tool for high-throughput crystallography of protein-ligand complexes. | Alexander W Schüttelkopf, Daan M F van Aalten | Acta Crystallogr D Biol Crystallogr | 2004 | 15272157 | Yes |
1249 | 1904 | 1904.0 | 62.37 | 62.4 | The molecular theory of polyelectrolyte solutions with applications to the electrostatic properties of polynucleotides. | G S Manning | Q Rev Biophys | 1978 | 353876 | No |
1250 | 1903 | 1903.0 | 46.23 | 46.2 | Episodic memory: from mind to brain. | Endel Tulving | Annu Rev Psychol | 2002 | 11752477 | Yes |
1251 | 7611 | 1902.8 | 2319.67 | 579.9 | Cancer statistics, 2022. | Rebecca L Siegel, Kimberly D Miller, Hannah E Fuchs, Ahmedin Jemal | CA Cancer J Clin | 2022 | 35020204 | Yes |
1252 | 1901 | 1901.0 | 54.38 | 54.4 | The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. | G P Chrousos | N Engl J Med | 1995 | 7715646 | No |
1253 | 5700 | 1900.0 | 336.8 | 112.3 | Research diagnostic criteria: rationale and reliability. | R L Spitzer, J Endicott, E Robins | Arch Gen Psychiatry | 1978 | 655775 | Yes |
1254 | 1900 | 1900.0 | 0.0 | 0.0 | The oxidation of ribonuclease with performic acid. | C H Hirs | J Biol Chem | 1956 | 13319283 | Yes |
1255 | 3799 | 1899.5 | 112.31 | 56.2 | Mechanisms of salinity tolerance. | Rana Munns, Mark Tester | Annu Rev Plant Biol | 2008 | 18444910 | No |
1256 | 1899 | 1899.0 | 47.03 | 47.0 | Pathogen recognition and inflammatory signaling in innate immune defenses. | Trine H Mogensen | Clin Microbiol Rev | 2009 | 19366914 | No |
1257 | 1898 | 1898.0 | 53.94 | 53.9 | In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain. | T R Chen | Exp Cell Res | 1977 | 65285 | Yes |
1258 | 1897 | 1897.0 | 24.72 | 24.7 | A theory of cerebellar cortex. | D Marr | J Physiol | 1969 | 5784296 | Yes |
1259 | 3787 | 1893.5 | 134.87 | 67.4 | ITS primers with enhanced specificity for basidiomycetes--application to the identification of mycorrhizae and rusts. | M Gardes, T D Bruns | Mol Ecol | 1993 | 8180733 | Yes |
1260 | 1893 | 1893.0 | 69.8 | 69.8 | Pro-resolving lipid mediators are leads for resolution physiology. | Charles N Serhan | Nature | 2014 | 24899309 | No |
1261 | 1891 | 1891.0 | 41.02 | 41.0 | The mitogen-activated protein kinase signal transduction pathway. | R J Davis | J Biol Chem | 1993 | 8325833 | No |
1262 | 3781 | 1890.5 | 86.42 | 43.2 | The Fas death factor. | S Nagata, P Golstein | Science | 1995 | 7533326 | No |
1263 | 3780 | 1890.0 | 112.01 | 56.0 | Individual differences in two emotion regulation processes: implications for affect, relationships, and well-being. | James J Gross, Oliver P John | J Pers Soc Psychol | 2003 | 12916575 | Yes |
1264 | 1890 | 1890.0 | 43.25 | 43.2 | Targeting PI3K signalling in cancer: opportunities, challenges and limitations. | Jeffrey A Engelman | Nat Rev Cancer | 2009 | 19629070 | No |
1265 | 3779 | 1889.5 | 88.76 | 44.4 | Neuronal oscillations in cortical networks. | György Buzsáki, Andreas Draguhn | Science | 2004 | 15218136 | No |
1266 | 20780 | 1889.1 | 519.15 | 47.2 | PLINK: a tool set for whole-genome association and population-based linkage analyses. | Shaun Purcell, Benjamin Neale, Kathe Todd-Brown, Lori Thomas, Manuel A R Ferreira, David Bender, Julian Maller, Pamela Sklar, Paul I W de Bakker, Mark J Daly, Pak C Sham | Am J Hum Genet | 2007 | 17701901 | Yes |
1267 | 3777 | 1888.5 | 132.98 | 66.5 | Reactive oxygen species and antioxidant machinery in abiotic stress tolerance in crop plants. | Sarvajeet Singh Gill, Narendra Tuteja | Plant Physiol Biochem | 2010 | 20870416 | No |
1268 | 1888 | 1888.0 | 59.52 | 59.5 | Complete nucleotide sequence of the Escherichia coli plasmid pBR322. | J G Sutcliffe | Cold Spring Harb Symp Quant Biol | 1979 | 383387 | Yes |
1269 | 3776 | 1888.0 | 84.93 | 42.5 | Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. | T Miyashita, J C Reed | Cell | 1995 | 7834749 | Yes |
1270 | 1887 | 1887.0 | 17.5 | 17.5 | Positional information and the spatial pattern of cellular differentiation. | L Wolpert | J Theor Biol | 1969 | 4390734 | Yes |
1271 | 3774 | 1887.0 | 128.65 | 64.3 | Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. | M H Zweig, G Campbell | Clin Chem | 1993 | 8472349 | No |
1272 | 1886 | 1886.0 | 45.53 | 45.5 | Python: a programming language for software integration and development. | M F Sanner | J Mol Graph Model | 1999 | 10660911 | Yes |
1273 | 3772 | 1886.0 | 84.09 | 42.0 | Parkinson's disease: mechanisms and models. | William Dauer, Serge Przedborski | Neuron | 2003 | 12971891 | No |
1274 | 3770 | 1885.0 | 112.09 | 56.0 | An efficient mRNA-dependent translation system from reticulocyte lysates. | H R Pelham, R J Jackson | Eur J Biochem | 1976 | 823012 | Yes |
1275 | 1885 | 1885.0 | 59.17 | 59.2 | Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders. | Berislav V Zlokovic | Nat Rev Neurosci | 2011 | 22048062 | No |
1276 | 3763 | 1881.5 | 89.66 | 44.8 | The future of genetic studies of complex human diseases. | N Risch, K Merikangas | Science | 1996 | 8801636 | Yes |
1277 | 1880 | 1880.0 | 45.21 | 45.2 | The genetics of ageing. | Cynthia J Kenyon | Nature | 2010 | 20336132 | No |
1278 | 1879 | 1879.0 | 0.0 | 0.0 | Dendritic organization in the neurons of the visual and motor cortices of the cat. | D A Sholl | J Anat | 1953 | 13117757 | Yes |
1279 | 1879 | 1879.0 | 64.02 | 64.0 | Guided Search 2.0 A revised model of visual search. | J M Wolfe | Psychon Bull Rev | 1994 | 24203471 | Yes |
1280 | 5630 | 1876.7 | 144.14 | 48.0 | Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. | G S Hotamisligil, N S Shargill, B M Spiegelman | Science | 1993 | 7678183 | Yes |
1281 | 1876 | 1876.0 | 52.89 | 52.9 | Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis. | A Dunaif | Endocr Rev | 1997 | 9408743 | No |
1282 | 1876 | 1876.0 | 41.32 | 41.3 | Cellular mechanisms of insulin resistance. | G I Shulman | J Clin Invest | 2000 | 10903330 | No |
1283 | 3751 | 1875.5 | 126.62 | 63.3 | Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. | G Di Chiara, A Imperato | Proc Natl Acad Sci U S A | 1988 | 2899326 | Yes |
1284 | 1875 | 1875.0 | 86.76 | 86.8 | A simple fluorometric assay for lipoperoxide in blood plasma. | K Yagi | Biochem Med | 1976 | 962904 | Yes |
1285 | 1875 | 1875.0 | 50.9 | 50.9 | A computational procedure for determining energetically favorable binding sites on biologically important macromolecules. | P J Goodford | J Med Chem | 1985 | 3892003 | Yes |
1286 | 1874 | 1874.0 | 69.27 | 69.3 | Recognition-by-components: a theory of human image understanding. | Irving Biederman | Psychol Rev | 1987 | 3575582 | Yes |
1287 | 7492 | 1873.0 | 251.98 | 63.0 | Reporting results of cancer treatment. | A B Miller, B Hoogstraten, M Staquet, A Winkler | Cancer | 1981 | 7459811 | Yes |
1288 | 7481 | 1870.2 | 184.37 | 46.1 | Epithelial-mesenchymal transitions in development and disease. | Jean Paul Thiery, Hervé Acloque, Ruby Y J Huang, M Angela Nieto | Cell | 2009 | 19945376 | No |
1289 | 1870 | 1870.0 | 41.77 | 41.8 | The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. | Michael R Lieber | Annu Rev Biochem | 2010 | 20192759 | No |
1290 | 3738 | 1869.0 | 105.86 | 52.9 | Event-related EEG/MEG synchronization and desynchronization: basic principles. | G Pfurtscheller, F H Lopes da Silva | Clin Neurophysiol | 1999 | 10576479 | No |
1291 | 5607 | 1869.0 | 243.1 | 81.0 | Scoping studies: advancing the methodology. | Danielle Levac, Heather Colquhoun, Kelly K O'Brien | Implement Sci | 2010 | 20854677 | Yes |
1292 | 3735 | 1867.5 | 79.15 | 39.6 | Raster3D: photorealistic molecular graphics. | E A Merritt, D J Bacon | Methods Enzymol | 1997 | 18488322 | Yes |
1293 | 1867 | 1867.0 | 51.9 | 51.9 | Cell biology and molecular basis of denitrification. | W G Zumft | Microbiol Mol Biol Rev | 1997 | 9409151 | No |
1294 | 1867 | 1867.0 | 40.01 | 40.0 | Exploring complex networks. | S H Strogatz | Nature | 2001 | 11258382 | No |
1295 | 3733 | 1866.5 | 129.12 | 64.6 | PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data. | Daniel R Roe, Thomas E Cheatham | J Chem Theory Comput | 2013 | 26583988 | Yes |
1296 | 1865 | 1865.0 | 53.44 | 53.4 | Multiple imputation: a primer. | J L Schafer | Stat Methods Med Res | 1999 | 10347857 | No |
1297 | 5592 | 1864.0 | 125.42 | 41.8 | A new statistical method for haplotype reconstruction from population data. | M Stephens, N J Smith, P Donnelly | Am J Hum Genet | 2001 | 11254454 | Yes |
1298 | 1864 | 1864.0 | 45.14 | 45.1 | The hydrogen bond in the solid state. | Thomas Steiner | Angew Chem Int Ed Engl | 2002 | 12491444 | Yes |
1299 | 1862 | 1862.0 | 68.14 | 68.1 | Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury. | D R Janero | Free Radic Biol Med | 1990 | 2079232 | No |
1300 | 14890 | 1861.2 | 364.36 | 45.5 | Electric field effect in atomically thin carbon films. | K S Novoselov, A K Geim, S V Morozov, D Jiang, Y Zhang, S V Dubonos, I V Grigorieva, A A Firsov | Science | 2004 | 15499015 | Yes |
1301 | 11166 | 1861.0 | 617.36 | 102.9 | DADA2: High-resolution sample inference from Illumina amplicon data. | Benjamin J Callahan, Paul J McMurdie, Michael J Rosen, Andrew W Han, Amy Jo A Johnson, Susan P Holmes | Nat Methods | 2016 | 27214047 | Yes |
1302 | 3720 | 1860.0 | 67.98 | 34.0 | Rho GTPases in cell biology. | Sandrine Etienne-Manneville, Alan Hall | Nature | 2002 | 12478284 | No |
1303 | 1859 | 1859.0 | 41.65 | 41.6 | Fabrication of novel biomaterials through molecular self-assembly. | Shuguang Zhang | Nat Biotechnol | 2003 | 14520402 | No |
1304 | 1858 | 1858.0 | 53.8 | 53.8 | Molecular weight determination of protein-dodecyl sulfate complexes by gel electrophoresis in a discontinuous buffer system. | D M Neville | J Biol Chem | 1971 | 5127429 | Yes |
1305 | 1857 | 1857.0 | 48.54 | 48.5 | Hepatitis B virus infection. | W M Lee | N Engl J Med | 1997 | 9392700 | No |
1306 | 1856 | 1856.0 | 37.32 | 37.3 | Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. | R J Kaufman | Genes Dev | 1999 | 10346810 | No |
1307 | 12988 | 1855.4 | 463.75 | 66.2 | Assessing the quality of reports of randomized clinical trials: is blinding necessary? | A R Jadad, R A Moore, D Carroll, C Jenkinson, D J Reynolds, D J Gavaghan, H J McQuay | Control Clin Trials | 1996 | 8721797 | Yes |
1308 | 1854 | 1854.0 | 43.02 | 43.0 | The retinal pigment epithelium in visual function. | Olaf Strauss | Physiol Rev | 2005 | 15987797 | No |
1309 | 5558 | 1852.7 | 138.81 | 46.3 | Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. | Z N Oltvai, C L Milliman, S J Korsmeyer | Cell | 1993 | 8358790 | Yes |
1310 | 3705 | 1852.5 | 76.62 | 38.3 | Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. | C D Nobes, A Hall | Cell | 1995 | 7536630 | Yes |
1311 | 1851 | 1851.0 | 113.79 | 113.8 | Understanding Bland Altman analysis. | Davide Giavarina | Biochem Med (Zagreb) | 2015 | 26110027 | No |
1312 | 3698 | 1849.0 | 111.76 | 55.9 | Photoperoxidation in isolated chloroplasts. I. Kinetics and stoichiometry of fatty acid peroxidation. | R L Heath, L Packer | Arch Biochem Biophys | 1968 | 5655425 | Yes |
1313 | 3697 | 1848.5 | 116.37 | 58.2 | Understanding interobserver agreement: the kappa statistic. | Anthony J Viera, Joanne M Garrett | Fam Med | 2005 | 15883903 | Yes |
1314 | 3695 | 1847.5 | 37.8 | 18.9 | Immunoassay of insulin with insulin-antibody precipitate. | C N Hales, P J Randle | Biochem J | 1963 | 13952078 | Yes |
1315 | 1847 | 1847.0 | 46.67 | 46.7 | Protein denaturation. | C Tanford | Adv Protein Chem | 1968 | 4882248 | No |
1316 | 1847 | 1847.0 | 49.27 | 49.3 | Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic. | Robert E Marx | J Oral Maxillofac Surg | 2003 | 12966493 | Yes |
1317 | 14768 | 1846.0 | 415.6 | 52.0 | Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. | R K Saiki, D H Gelfand, S Stoffel, S J Scharf, R Higuchi, G T Horn, K B Mullis, H A Erlich | Science | 1988 | 2448875 | Yes |
1318 | 1846 | 1846.0 | 41.78 | 41.8 | Integrating cell-signalling pathways with NF-kappaB and IKK function. | Neil D Perkins | Nat Rev Mol Cell Biol | 2007 | 17183360 | No |
1319 | 1845 | 1845.0 | 41.46 | 41.5 | Global cancer statistics in the year 2000. | D M Parkin | Lancet Oncol | 2001 | 11905707 | No |
1320 | 3690 | 1845.0 | 112.58 | 56.3 | Threshold-free cluster enhancement: addressing problems of smoothing, threshold dependence and localisation in cluster inference. | Stephen M Smith, Thomas E Nichols | Neuroimage | 2009 | 18501637 | Yes |
1321 | 3689 | 1844.5 | 78.02 | 39.0 | Monocyte and macrophage heterogeneity. | Siamon Gordon, Philip R Taylor | Nat Rev Immunol | 2005 | 16322748 | No |
1322 | 1843 | 1843.0 | 44.83 | 44.8 | Evolutionary relationship of DNA sequences in finite populations. | F Tajima | Genetics | 1983 | 6628982 | Yes |
1323 | 1843 | 1843.0 | 77.22 | 77.2 | The drug abuse screening test. | H A Skinner | Addict Behav | 1982 | 7183189 | Yes |
1324 | 1842 | 1842.0 | 96.32 | 96.3 | Subjective well-being. | E Diener | Psychol Bull | 1984 | 6399758 | No |
1325 | 1842 | 1842.0 | 43.66 | 43.7 | The mitochondrial permeability transition pore and its role in cell death. | M Crompton | Biochem J | 1999 | 10393078 | No |
1326 | 5520 | 1840.0 | 121.42 | 40.5 | A rapid method for the isolation of functional thymus-derived murine lymphocytes. | M H Julius, E Simpson, L A Herzenberg | Eur J Immunol | 1973 | 4587740 | Yes |
1327 | 1840 | 1840.0 | 68.25 | 68.2 | Physiological aspects of primary hypertension. | B Folkow | Physiol Rev | 1982 | 6461865 | No |
1328 | 1840 | 1840.0 | 41.61 | 41.6 | DNA topoisomerases. | J C Wang | Annu Rev Biochem | 1996 | 8811192 | No |
1329 | 7358 | 1839.5 | 177.88 | 44.5 | Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. | A Shevchenko, M Wilm, O Vorm, M Mann | Anal Chem | 1996 | 8779443 | Yes |
1330 | 7355 | 1838.8 | 336.32 | 84.1 | Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. | D J Sahn, A DeMaria, J Kisslo, A Weyman | Circulation | 1978 | 709763 | Yes |
1331 | 1838 | 1838.0 | 66.19 | 66.2 | Why patients use alternative medicine: results of a national study. | J A Astin | JAMA | 1998 | 9605899 | Yes |
1332 | 1838 | 1838.0 | 48.47 | 48.5 | The comet assay for DNA damage and repair: principles, applications, and limitations. | Andrew R Collins | Mol Biotechnol | 2004 | 15004294 | No |
1333 | 3675 | 1837.5 | 76.25 | 38.1 | Identification of common molecular subsequences. | T F Smith, M S Waterman | J Mol Biol | 1981 | 7265238 | Yes |
1334 | 1835 | 1835.0 | 55.64 | 55.6 | The atom economy--a search for synthetic efficiency. | B M Trost | Science | 1991 | 1962206 | Yes |
1335 | 3669 | 1834.5 | 109.81 | 54.9 | Development of a new resilience scale: the Connor-Davidson Resilience Scale (CD-RISC). | Kathryn M Connor, Jonathan R T Davidson | Depress Anxiety | 2003 | 12964174 | Yes |
1336 | 3668 | 1834.0 | 120.28 | 60.1 | Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. | R A DeFronzo, E Ferrannini | Diabetes Care | 1991 | 2044434 | No |
1337 | 9169 | 1833.8 | 219.31 | 43.9 | Mapping and quantifying mammalian transcriptomes by RNA-Seq. | Ali Mortazavi, Brian A Williams, Kenneth McCue, Lorian Schaeffer, Barbara Wold | Nat Methods | 2008 | 18516045 | Yes |
1338 | 1833 | 1833.0 | 57.67 | 57.7 | The Gingival Index, the Plaque Index and the Retention Index Systems. | H Löe | J Periodontol | 1967 | 5237684 | Yes |
1339 | 1833 | 1833.0 | 37.27 | 37.3 | The lasso method for variable selection in the Cox model. | R Tibshirani | Stat Med | 1997 | 9044528 | Yes |
1340 | 1833 | 1833.0 | 54.2 | 54.2 | An overview of brominated flame retardants in the environment. | Cynthia A de Wit | Chemosphere | 2002 | 11999784 | No |
1341 | 5493 | 1831.0 | 121.55 | 40.5 | Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. | Michael W Pfaffl, Graham W Horgan, Leo Dempfle | Nucleic Acids Res | 2002 | 11972351 | Yes |
1342 | 1830 | 1830.0 | 45.02 | 45.0 | Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials. | Fiona Turnbull | Lancet | 2003 | 14615107 | Yes |
1343 | 5482 | 1827.3 | 249.36 | 83.1 | Fast and sensitive protein alignment using DIAMOND. | Benjamin Buchfink, Chao Xie, Daniel H Huson | Nat Methods | 2015 | 25402007 | Yes |
1344 | 1827 | 1827.0 | 49.3 | 49.3 | A classification of hand preference by association analysis. | M Annett | Br J Psychol | 1970 | 5457503 | Yes |
1345 | 1827 | 1827.0 | 36.46 | 36.5 | MicroRNA biogenesis: coordinated cropping and dicing. | V Narry Kim | Nat Rev Mol Cell Biol | 2005 | 15852042 | No |
1346 | 1826 | 1826.0 | 48.3 | 48.3 | Molecular dissection of reactive astrogliosis and glial scar formation. | Michael V Sofroniew | Trends Neurosci | 2009 | 19782411 | No |
1347 | 3648 | 1824.0 | 110.5 | 55.2 | New method for quantitative determination of uronic acids. | N Blumenkrantz, G Asboe-Hansen | Anal Biochem | 1973 | 4269305 | Yes |
1348 | 1824 | 1824.0 | 46.83 | 46.8 | From sensation to cognition. | M M Mesulam | Brain | 1998 | 9648540 | No |
1349 | 1824 | 1824.0 | 12.83 | 12.8 | A Method Of Measuring Eye Movement Using A Scleral Search Coil In A Magnetic Field. | D A Robinson | IEEE Trans Biomed Eng | 1963 | 14121113 | Yes |
1350 | 1824 | 1824.0 | 57.28 | 57.3 | Matching methods for causal inference: A review and a look forward. | Elizabeth A Stuart | Stat Sci | 2010 | 20871802 | Yes |
1351 | 3646 | 1823.0 | 81.4 | 40.7 | Amino acid substitution matrices from protein blocks. | S Henikoff, J G Henikoff | Proc Natl Acad Sci U S A | 1992 | 1438297 | Yes |
1352 | 3646 | 1823.0 | 76.12 | 38.1 | Cell death: critical control points. | Nika N Danial, Stanley J Korsmeyer | Cell | 2004 | 14744432 | No |
1353 | 1822 | 1822.0 | 83.95 | 84.0 | Determinants of low birth weight: methodological assessment and meta-analysis. | M S Kramer | Bull World Health Organ | 1987 | 3322602 | No |
1354 | 1821 | 1821.0 | 35.45 | 35.5 | Cancer and the chemokine network. | Fran Balkwill | Nat Rev Cancer | 2004 | 15229479 | No |
1355 | 1821 | 1821.0 | 50.04 | 50.0 | Systemic lupus erythematosus. | George C Tsokos | N Engl J Med | 2011 | 22129255 | No |
1356 | 3637 | 1818.5 | 131.41 | 65.7 | miRBase: annotating high confidence microRNAs using deep sequencing data. | Ana Kozomara, Sam Griffiths-Jones | Nucleic Acids Res | 2014 | 24275495 | Yes |
1357 | 1817 | 1817.0 | 0.0 | 0.0 | The influence of some cations on an adenosine triphosphatase from peripheral nerves. | J C Skou | Biochim Biophys Acta | 1957 | 13412736 | Yes |
1358 | 1817 | 1817.0 | 59.27 | 59.3 | Cognitive reserve. | Yaakov Stern | Neuropsychologia | 2009 | 19467352 | No |
1359 | 1816 | 1816.0 | 69.85 | 69.8 | Reliability and validity studies of the WHO--Composite International Diagnostic Interview (CIDI): a critical review. | H U Wittchen | J Psychiatr Res | 1994 | 8064641 | No |
1360 | 3631 | 1815.5 | 98.8 | 49.4 | Biofilms: survival mechanisms of clinically relevant microorganisms. | Rodney M Donlan, J William Costerton | Clin Microbiol Rev | 2002 | 11932229 | No |
1361 | 1815 | 1815.0 | 36.48 | 36.5 | Evolutionary rate at the molecular level. | M Kimura | Nature | 1968 | 5637732 | Yes |
1362 | 5442 | 1814.0 | 194.95 | 65.0 | Molecular mechanisms of epithelial-mesenchymal transition. | Samy Lamouille, Jian Xu, Rik Derynck | Nat Rev Mol Cell Biol | 2014 | 24556840 | No |
1363 | 3628 | 1814.0 | 127.18 | 63.6 | Regulation of microRNA biogenesis. | Minju Ha, V Narry Kim | Nat Rev Mol Cell Biol | 2014 | 25027649 | No |
1364 | 1813 | 1813.0 | 36.7 | 36.7 | Molecular regulation of vessel maturation. | Rakesh K Jain | Nat Med | 2003 | 12778167 | No |
1365 | 3626 | 1813.0 | 307.53 | 153.8 | The biology, function, and biomedical applications of exosomes. | Raghu Kalluri, Valerie S LeBleu | Science | 2020 | 32029601 | No |
1366 | 5437 | 1812.3 | 161.93 | 54.0 | Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration. | Helga Thorvaldsdóttir, James T Robinson, Jill P Mesirov | Brief Bioinform | 2013 | 22517427 | Yes |
1367 | 1810 | 1810.0 | 59.01 | 59.0 | Heavy metal intensification of DAB-based HRP reaction product. | J C Adams | J Histochem Cytochem | 1981 | 7252134 | Yes |
1368 | 5429 | 1809.7 | 481.08 | 160.4 | An interactive web-based dashboard to track COVID-19 in real time. | Ensheng Dong, Hongru Du, Lauren Gardner | Lancet Infect Dis | 2020 | 32087114 | Yes |
1369 | 3615 | 1807.5 | 96.4 | 48.2 | Variations in the pattern of pubertal changes in boys. | W A Marshall, J M Tanner | Arch Dis Child | 1970 | 5440182 | Yes |
1370 | 1807 | 1807.0 | 70.67 | 70.7 | Predicting basal metabolic rate, new standards and review of previous work. | W N Schofield | Hum Nutr Clin Nutr | 1985 | 4044297 | Yes |
1371 | 1806 | 1806.0 | 57.35 | 57.4 | Postsynaptic supersensitivity after 6-hydroxy-dopamine induced degeneration of the nigro-striatal dopamine system. | U Ungerstedt | Acta Physiol Scand Suppl | 1971 | 4332693 | Yes |
1372 | 1805 | 1805.0 | 48.54 | 48.5 | New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. | R Y Tsien | Biochemistry | 1980 | 6770893 | Yes |
1373 | 3609 | 1804.5 | 92.13 | 46.1 | Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. | K D McCarthy, J de Vellis | J Cell Biol | 1980 | 6248568 | Yes |
1374 | 5412 | 1804.0 | 102.77 | 34.3 | Surfing the p53 network. | B Vogelstein, D Lane, A J Levine | Nature | 2000 | 11099028 | No |
1375 | 1804 | 1804.0 | 18.63 | 18.6 | Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal. | S Cohen | J Biol Chem | 1962 | 13880319 | Yes |
1376 | 1803 | 1803.0 | 49.11 | 49.1 | Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution. | H LeVine | Protein Sci | 1993 | 8453378 | Yes |
1377 | 1801 | 1801.0 | 66.01 | 66.0 | The Resonating Valence Bond State in La2CuO4 and Superconductivity. | P W Anderson | Science | 1987 | 17818979 | Yes |
1378 | 3601 | 1800.5 | 104.67 | 52.3 | Molecular mechanisms and clinical applications of angiogenesis. | Peter Carmeliet, Rakesh K Jain | Nature | 2011 | 21593862 | No |
1379 | 1800 | 1800.0 | 39.49 | 39.5 | Gene finding in novel genomes. | Ian Korf | BMC Bioinformatics | 2004 | 15144565 | Yes |
1380 | 1798 | 1798.0 | 0.0 | 0.0 | Cognitive maps in rats and men. | E C Tolman | Psychol Rev | 1948 | 18870876 | Yes |
1381 | 7191 | 1797.8 | 174.59 | 43.6 | Improved optimization for the robust and accurate linear registration and motion correction of brain images. | Mark Jenkinson, Peter Bannister, Michael Brady, Stephen Smith | Neuroimage | 2002 | 12377157 | Yes |
1382 | 3594 | 1797.0 | 86.25 | 43.1 | Protein folding in the cell. | M J Gething, J Sambrook | Nature | 1992 | 1731198 | No |
1383 | 1795 | 1795.0 | 56.49 | 56.5 | Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. | M Zasloff | Proc Natl Acad Sci U S A | 1987 | 3299384 | Yes |
1384 | 3588 | 1794.0 | 159.65 | 79.8 | Multiple receptors for dopamine. | J W Kebabian, D B Calne | Nature | 1979 | 215920 | No |
1385 | 1794 | 1794.0 | 98.27 | 98.3 | Estimability and estimation in case-referent studies. | O Miettinen | Am J Epidemiol | 1976 | 1251836 | Yes |
1386 | 1793 | 1793.0 | 62.54 | 62.5 | A cortical network for directed attention and unilateral neglect. | M M Mesulam | Ann Neurol | 1981 | 7032417 | No |
1387 | 1793 | 1793.0 | 42.48 | 42.5 | Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. | D Lavanchy | J Viral Hepat | 2004 | 14996343 | No |
1388 | 1792 | 1792.0 | 51.37 | 51.4 | Perceptual symbol systems. | L W Barsalou | Behav Brain Sci | 1999 | 11301525 | No |
1389 | 3584 | 1792.0 | 87.09 | 43.5 | Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. | Christian Haass, Dennis J Selkoe | Nat Rev Mol Cell Biol | 2007 | 17245412 | No |
1390 | 1791 | 1791.0 | 35.88 | 35.9 | The effect of infections on susceptibility to autoimmune and allergic diseases. | Jean-Francois Bach | N Engl J Med | 2002 | 12239261 | No |
1391 | 1791 | 1791.0 | 0.0 | 0.0 | The measurement of volume changes in human limbs. | R J Whitney | J Physiol | 1953 | 13085295 | Yes |
1392 | 1791 | 1791.0 | 39.59 | 39.6 | Recognition of microorganisms and activation of the immune response. | Ruslan Medzhitov | Nature | 2007 | 17943118 | No |
1393 | 1789 | 1789.0 | 42.27 | 42.3 | Type III protein secretion systems in bacterial pathogens of animals and plants. | C J Hueck | Microbiol Mol Biol Rev | 1998 | 9618447 | No |
1394 | 1789 | 1789.0 | 67.32 | 67.3 | Cognitive reserve in ageing and Alzheimer's disease. | Yaakov Stern | Lancet Neurol | 2012 | 23079557 | No |
1395 | 8939 | 1787.8 | 234.36 | 46.9 | Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. | Sarah Wild, Gojka Roglic, Anders Green, Richard Sicree, Hilary King | Diabetes Care | 2004 | 15111519 | Yes |
1396 | 3574 | 1787.0 | 99.14 | 49.6 | EQ-5D: a measure of health status from the EuroQol Group. | R Rabin, F de Charro | Ann Med | 2001 | 11491192 | No |
1397 | 1787 | 1787.0 | 43.22 | 43.2 | Integration, scaling, space-group assignment and post-refinement. | Wolfgang Kabsch | Acta Crystallogr D Biol Crystallogr | 2010 | 20124693 | Yes |
1398 | 1786 | 1786.0 | 49.0 | 49.0 | Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus. | Ralph A Defronzo | Diabetes | 2009 | 19336687 | No |
1399 | 10714 | 1785.7 | 313.42 | 52.2 | Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. | Ronald C Kessler, Patricia Berglund, Olga Demler, Robert Jin, Kathleen R Merikangas, Ellen E Walters | Arch Gen Psychiatry | 2005 | 15939837 | Yes |
1400 | 3571 | 1785.5 | 94.1 | 47.0 | Receptive fields and functional architecture of monkey striate cortex. | D H Hubel, T N Wiesel | J Physiol | 1968 | 4966457 | Yes |
1401 | 3568 | 1784.0 | 177.81 | 88.9 | Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. | M Mihara, M Uchiyama | Anal Biochem | 1978 | 655387 | Yes |
1402 | 1784 | 1784.0 | 36.61 | 36.6 | Structure and regulation of voltage-gated Ca2+ channels. | W A Catterall | Annu Rev Cell Dev Biol | 2000 | 11031246 | No |
1403 | 1783 | 1783.0 | 116.3 | 116.3 | Toward understanding the origin and evolution of cellular organisms. | Minoru Kanehisa | Protein Sci | 2019 | 31441146 | No |
1404 | 1782 | 1782.0 | 58.43 | 58.4 | The crisis in antibiotic resistance. | H C Neu | Science | 1992 | 1509257 | No |
1405 | 3563 | 1781.5 | 88.53 | 44.3 | Maturation of the head of bacteriophage T4. I. DNA packaging events. | U K Laemmli, M Favre | J Mol Biol | 1973 | 4204102 | Yes |
1406 | 5343 | 1781.0 | 160.25 | 53.4 | Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. | P A Wolf, R D Abbott, W B Kannel | Stroke | 1991 | 1866765 | Yes |
1407 | 1780 | 1780.0 | 47.05 | 47.0 | Interleukin-6: an overview. | J Van Snick | Annu Rev Immunol | 1990 | 2188664 | No |
1408 | 1779 | 1779.0 | 58.77 | 58.8 | Large-scale neurocognitive networks and distributed processing for attention, language, and memory. | M M Mesulam | Ann Neurol | 1990 | 2260847 | No |
1409 | 7110 | 1777.5 | 197.68 | 49.4 | Comorbidity measures for use with administrative data. | A Elixhauser, C Steiner, D R Harris, R M Coffey | Med Care | 1998 | 9431328 | Yes |
1410 | 5330 | 1776.7 | 111.36 | 37.1 | A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays. | J H Zhang, T D Chung, K R Oldenburg | J Biomol Screen | 1999 | 10838414 | Yes |
1411 | 1776 | 1776.0 | 35.94 | 35.9 | Points of control in inflammation. | Carl Nathan | Nature | 2002 | 12490957 | No |
1412 | 1775 | 1775.0 | 32.83 | 32.8 | Cellular roles of DNA topoisomerases: a molecular perspective. | James C Wang | Nat Rev Mol Cell Biol | 2002 | 12042765 | No |
1413 | 1774 | 1774.0 | 48.48 | 48.5 | Leptospirosis. | P N Levett | Clin Microbiol Rev | 2001 | 11292640 | No |
1414 | 1773 | 1773.0 | 58.84 | 58.8 | Drugs of abuse: anatomy, pharmacology and function of reward pathways. | G F Koob | Trends Pharmacol Sci | 1992 | 1604710 | No |
1415 | 1773 | 1773.0 | 57.75 | 57.8 | Pineal melatonin: cell biology of its synthesis and of its physiological interactions. | R J Reiter | Endocr Rev | 1991 | 1649044 | No |
1416 | 1773 | 1773.0 | 49.33 | 49.3 | Porous scaffold design for tissue engineering. | Scott J Hollister | Nat Mater | 2005 | 16003400 | No |
1417 | 1772 | 1772.0 | 43.62 | 43.6 | Adipose tissue, adipokines, and inflammation. | Giamila Fantuzzi | J Allergy Clin Immunol | 2005 | 15867843 | No |
1418 | 1769 | 1769.0 | 53.92 | 53.9 | Social relationships and health. | Sheldon Cohen | Am Psychol | 2004 | 15554821 | No |
1419 | 1766 | 1766.0 | 57.38 | 57.4 | The inverse care law. | J T Hart | Lancet | 1971 | 4100731 | Yes |
1420 | 3532 | 1766.0 | 88.49 | 44.2 | The biology of vascular endothelial growth factor. | N Ferrara, T Davis-Smyth | Endocr Rev | 1997 | 9034784 | No |
1421 | 1765 | 1765.0 | 47.87 | 47.9 | G proteins and dual control of adenylate cyclase. | A G Gilman | Cell | 1984 | 6321035 | Yes |
1422 | 3527 | 1763.5 | 128.14 | 64.1 | The need to belong: desire for interpersonal attachments as a fundamental human motivation. | R F Baumeister, M R Leary | Psychol Bull | 1995 | 7777651 | No |
1423 | 1763 | 1763.0 | 37.73 | 37.7 | Oogenesis in Xenopus laevis (Daudin). I. Stages of oocyte development in laboratory maintained animals. | J N Dumont | J Morphol | 1972 | 4109871 | Yes |
1424 | 7052 | 1763.0 | 137.62 | 34.4 | Stem cells, cancer, and cancer stem cells. | T Reya, S J Morrison, M F Clarke, I L Weissman | Nature | 2001 | 11689955 | No |
1425 | 1762 | 1762.0 | 36.05 | 36.0 | An extensively modified version of MolScript that includes greatly enhanced coloring capabilities. | R M Esnouf | J Mol Graph Model | 1997 | 9385560 | Yes |
1426 | 1762 | 1762.0 | 0.0 | 0.0 | The reaction of acetylcholine and other carboxylic acid derivatives with hydroxylamine, and its analytical application. | S Hestrin | J Biol Chem | 1949 | 18133390 | Yes |
1427 | 1761 | 1761.0 | 42.47 | 42.5 | Growth of the plant cell wall. | Daniel J Cosgrove | Nat Rev Mol Cell Biol | 2005 | 16261190 | No |
1428 | 1761 | 1761.0 | 47.35 | 47.4 | What we can do and what we cannot do with fMRI. | Nikos K Logothetis | Nature | 2008 | 18548064 | No |
1429 | 1760 | 1760.0 | 44.82 | 44.8 | The pathophysiology of tumor necrosis factors. | P Vassalli | Annu Rev Immunol | 1992 | 1590993 | No |
1430 | 1760 | 1760.0 | 40.11 | 40.1 | Steroid receptor regulated transcription of specific genes and gene networks. | K R Yamamoto | Annu Rev Genet | 1985 | 3909942 | No |
1431 | 1760 | 1760.0 | 108.49 | 108.5 | Making sense of implementation theories, models and frameworks. | Per Nilsen | Implement Sci | 2015 | 25895742 | Yes |
1432 | 1759 | 1759.0 | 0.0 | 0.0 | A personality scale of manifest anxiety. | J A Taylor | J Abnorm Psychol | 1953 | 13052352 | Yes |
1433 | 1759 | 1759.0 | 46.38 | 46.4 | Oxidative stress and neurodegeneration: where are we now? | Barry Halliwell | J Neurochem | 2006 | 16805774 | No |
1434 | 1758 | 1758.0 | 61.07 | 61.1 | The role of hormone receptors and GTP-regulatory proteins in membrane transduction. | M Rodbell | Nature | 1980 | 6101906 | Yes |
1435 | 1758 | 1758.0 | 49.16 | 49.2 | Oxidative stress: oxidants and antioxidants. | H Sies | Exp Physiol | 1997 | 9129943 | No |
1436 | 5274 | 1758.0 | 139.0 | 46.3 | Median-joining networks for inferring intraspecific phylogenies. | H J Bandelt, P Forster, A Röhl | Mol Biol Evol | 1999 | 10331250 | Yes |
1437 | 17573 | 1757.3 | 549.91 | 55.0 | Measurement of protein using bicinchoninic acid. | P K Smith, R I Krohn, G T Hermanson, A K Mallia, F H Gartner, M D Provenzano, E K Fujimoto, N M Goeke, B J Olson, D C Klenk | Anal Biochem | 1985 | 3843705 | Yes |
1438 | 1757 | 1757.0 | 48.81 | 48.8 | Transposition and fusion of the lac genes to selected promoters in Escherichia coli using bacteriophage lambda and Mu. | M J Casadaban | J Mol Biol | 1976 | 781293 | Yes |
1439 | 3512 | 1756.0 | 86.57 | 43.3 | Matrix metalloproteinases. | H Nagase, J F Woessner | J Biol Chem | 1999 | 10419448 | No |
1440 | 1755 | 1755.0 | 18.61 | 18.6 | Chromatin structure: a repeating unit of histones and DNA. | R D Kornberg | Science | 1974 | 4825889 | Yes |
1441 | 3508 | 1754.0 | 108.5 | 54.2 | Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. | F Denizot, R Lang | J Immunol Methods | 1986 | 3486233 | Yes |
1442 | 3508 | 1754.0 | 136.57 | 68.3 | Assays of glutathione peroxidase. | L Flohé, W A Günzler | Methods Enzymol | 1984 | 6727659 | Yes |
1443 | 1754 | 1754.0 | 35.89 | 35.9 | Protein homology detection by HMM-HMM comparison. | Johannes Söding | Bioinformatics | 2005 | 15531603 | Yes |
1444 | 3507 | 1753.5 | 49.03 | 24.5 | A complementation analysis of the restriction and modification of DNA in Escherichia coli. | H W Boyer, D Roulland-Dussoix | J Mol Biol | 1969 | 4896022 | Yes |
1445 | 3507 | 1753.5 | 90.32 | 45.2 | Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation. | M A Nitsche, W Paulus | J Physiol | 2000 | 10990547 | Yes |
1446 | 1753 | 1753.0 | 38.81 | 38.8 | The synaptic vesicle cycle: a cascade of protein-protein interactions. | T C Südhof | Nature | 1995 | 7791897 | No |
1447 | 1752 | 1752.0 | 40.64 | 40.6 | Areas, volumes, packing and protein structure. | F M Richards | Annu Rev Biophys Bioeng | 1977 | 326146 | No |
1448 | 5256 | 1752.0 | 139.13 | 46.4 | The metabolic syndrome--a new worldwide definition. | K George M M Alberti, Paul Zimmet, Jonathan Shaw | Lancet | 2005 | 16182882 | Yes |
1449 | 1751 | 1751.0 | 43.66 | 43.7 | Flavonoid biosynthesis. A colorful model for genetics, biochemistry, cell biology, and biotechnology. | B Winkel-Shirley | Plant Physiol | 2001 | 11402179 | No |
1450 | 12252 | 1750.3 | 296.56 | 42.4 | Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. | William C Knowler, Elizabeth Barrett-Connor, Sarah E Fowler, Richard F Hamman, John M Lachin, Elizabeth A Walker, David M Nathan | N Engl J Med | 2002 | 11832527 | Yes |
1451 | 1750 | 1750.0 | 36.44 | 36.4 | Excitatory actions of gaba during development: the nature of the nurture. | Yehezkel Ben-Ari | Nat Rev Neurosci | 2002 | 12209121 | No |
1452 | 1750 | 1750.0 | 46.0 | 46.0 | Chlorpromazine equivalent doses for the newer atypical antipsychotics. | Scott W Woods | J Clin Psychiatry | 2003 | 12823080 | No |
1453 | 7000 | 1750.0 | 270.3 | 67.6 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | Int J Surg | 2010 | 20171303 | No |
1454 | 1749 | 1749.0 | 55.03 | 55.0 | The stress response in fish. | S E Wendelaar Bonga | Physiol Rev | 1997 | 9234959 | No |
1455 | 6995 | 1748.8 | 382.18 | 95.5 | fastp: an ultra-fast all-in-one FASTQ preprocessor. | Shifu Chen, Yanqing Zhou, Yaru Chen, Jia Gu | Bioinformatics | 2018 | 30423086 | Yes |
1456 | 3496 | 1748.0 | 92.71 | 46.4 | Prediction of protein antigenic determinants from amino acid sequences. | T P Hopp, K R Woods | Proc Natl Acad Sci U S A | 1981 | 6167991 | Yes |
1457 | 3496 | 1748.0 | 125.4 | 62.7 | Pain assessment: global use of the Brief Pain Inventory. | C S Cleeland, K M Ryan | Ann Acad Med Singap | 1994 | 8080219 | No |
1458 | 3495 | 1747.5 | 138.5 | 69.2 | ROS function in redox signaling and oxidative stress. | Michael Schieber, Navdeep S Chandel | Curr Biol | 2014 | 24845678 | No |
1459 | 1746 | 1746.0 | 44.01 | 44.0 | Hydrogels for biomedical applications. | Allan S Hoffman | Adv Drug Deliv Rev | 2002 | 11755703 | No |
1460 | 1746 | 1746.0 | 38.51 | 38.5 | The hippo signaling pathway in development and cancer. | Duojia Pan | Dev Cell | 2010 | 20951342 | No |
1461 | 1745 | 1745.0 | 57.2 | 57.2 | Serum albumin. | T Peters | Adv Protein Chem | 1985 | 3904348 | No |
1462 | 3489 | 1744.5 | 74.28 | 37.1 | Insulin signalling and the regulation of glucose and lipid metabolism. | A R Saltiel, C R Kahn | Nature | 2001 | 11742412 | Yes |
1463 | 1744 | 1744.0 | 33.54 | 33.5 | Transplacental carcinogenesis by stilbestrol. | J Folkman | N Engl J Med | 1971 | 5556579 | Yes |
1464 | 1744 | 1744.0 | 42.13 | 42.1 | Clinical application of C-reactive protein for cardiovascular disease detection and prevention. | Paul M Ridker | Circulation | 2003 | 12551853 | No |
1465 | 1743 | 1743.0 | 41.9 | 41.9 | Why genes in pieces? | W Gilbert | Nature | 1978 | 622185 | Yes |
1466 | 1743 | 1743.0 | 37.73 | 37.7 | ATPase activity of myosin correlated with speed of muscle shortening. | M Bárány | J Gen Physiol | 1967 | 4227924 | Yes |
1467 | 3486 | 1743.0 | 72.99 | 36.5 | Why do cancers have high aerobic glycolysis? | Robert A Gatenby, Robert J Gillies | Nat Rev Cancer | 2004 | 15516961 | No |
1468 | 1742 | 1742.0 | 71.58 | 71.6 | Dynamic properties of mammalian skeletal muscles. | R I Close | Physiol Rev | 1972 | 4256989 | No |
1469 | 1742 | 1742.0 | 54.48 | 54.5 | Glutamate: a neurotransmitter in mammalian brain. | F Fonnum | J Neurochem | 1984 | 6139418 | No |
1470 | 3482 | 1741.0 | 94.68 | 47.3 | Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. | K B Mullis, F A Faloona | Methods Enzymol | 1987 | 3431465 | Yes |
1471 | 1740 | 1740.0 | 46.93 | 46.9 | Oxidative stress hypothesis in Alzheimer's disease. | W R Markesbery | Free Radic Biol Med | 1997 | 9165306 | No |
1472 | 3480 | 1740.0 | 96.92 | 48.5 | The precuneus: a review of its functional anatomy and behavioural correlates. | Andrea E Cavanna, Michael R Trimble | Brain | 2006 | 16399806 | No |
1473 | 3479 | 1739.5 | 85.25 | 42.6 | Macrophage diversity enhances tumor progression and metastasis. | Bin-Zhi Qian, Jeffrey W Pollard | Cell | 2010 | 20371344 | No |
1474 | 3477 | 1738.5 | 73.07 | 36.5 | Integrin signaling. | F G Giancotti, E Ruoslahti | Science | 1999 | 10446041 | No |
1475 | 1738 | 1738.0 | 61.85 | 61.9 | Cyclosporine. | B D Kahan | N Engl J Med | 1989 | 2687689 | No |
1476 | 3472 | 1736.0 | 122.48 | 61.2 | The transtheoretical model of health behavior change. | J O Prochaska, W F Velicer | Am J Health Promot | 1997 | 10170434 | No |
1477 | 1736 | 1736.0 | 58.7 | 58.7 | Functional and effective connectivity: a review. | Karl J Friston | Brain Connect | 2011 | 22432952 | No |
1478 | 3471 | 1735.5 | 92.14 | 46.1 | The mirror-neuron system. | Giacomo Rizzolatti, Laila Craighero | Annu Rev Neurosci | 2004 | 15217330 | No |
1479 | 3471 | 1735.5 | 148.48 | 74.2 | mTOR Signaling in Growth, Metabolism, and Disease. | Robert A Saxton, David M Sabatini | Cell | 2017 | 28283069 | No |
1480 | 1735 | 1735.0 | 40.68 | 40.7 | Solvent-accessible surfaces of proteins and nucleic acids. | M L Connolly | Science | 1983 | 6879170 | Yes |
1481 | 6939 | 1734.8 | 135.57 | 33.9 | Transformation of intact yeast cells treated with alkali cations. | H Ito, Y Fukuda, K Murata, A Kimura | J Bacteriol | 1983 | 6336730 | Yes |
1482 | 3469 | 1734.5 | 113.71 | 56.9 | Saliency, switching, attention and control: a network model of insula function. | Vinod Menon, Lucina Q Uddin | Brain Struct Funct | 2010 | 20512370 | No |
1483 | 3468 | 1734.0 | 91.02 | 45.5 | Cloned glutamate receptors. | M Hollmann, S Heinemann | Annu Rev Neurosci | 1994 | 8210177 | No |
1484 | 5200 | 1733.3 | 112.65 | 37.6 | Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. | A Nicholls, K A Sharp, B Honig | Proteins | 1991 | 1758883 | Yes |
1485 | 1733 | 1733.0 | 31.42 | 31.4 | CD4+ CD25+ suppressor T cells: more questions than answers. | Ethan M Shevach | Nat Rev Immunol | 2002 | 12093005 | No |
1486 | 1732 | 1732.0 | 40.8 | 40.8 | Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining. | A Krishan | J Cell Biol | 1975 | 49354 | Yes |
1487 | 1732 | 1732.0 | 64.7 | 64.7 | Simple proton spectroscopic imaging. | W T Dixon | Radiology | 1984 | 6089263 | Yes |
1488 | 1731 | 1731.0 | 35.43 | 35.4 | Oxidative stress shortens telomeres. | Thomas von Zglinicki | Trends Biochem Sci | 2002 | 12114022 | Yes |
1489 | 1730 | 1730.0 | 38.28 | 38.3 | Mode of cell migration to the superficial layers of fetal monkey neocortex. | P Rakic | J Comp Neurol | 1972 | 4624784 | Yes |
1490 | 1730 | 1730.0 | 74.35 | 74.3 | Optical properties of biological tissues: a review. | Steven L Jacques | Phys Med Biol | 2013 | 23666068 | No |
1491 | 1729 | 1729.0 | 59.4 | 59.4 | Free radicals, antioxidants, and human disease: curiosity, cause, or consequence? | B Halliwell | Lancet | 1994 | 7915779 | No |
1492 | 1729 | 1729.0 | 36.4 | 36.4 | Maintenance of C. elegans. | Theresa Stiernagle | WormBook | 2006 | 18050451 | No |
1493 | 3457 | 1728.5 | 118.92 | 59.5 | The Oswestry Disability Index. | J C Fairbank, P B Pynsent | Spine (Phila Pa 1976) | 2000 | 11074683 | No |
1494 | 3457 | 1728.5 | 99.44 | 49.7 | Alzheimer's disease. | Henry W Querfurth, Frank M LaFerla | N Engl J Med | 2010 | 20107219 | No |
1495 | 1728 | 1728.0 | 65.4 | 65.4 | Antibiotics in the aquatic environment--a review--part I. | Klaus Kümmerer | Chemosphere | 2009 | 19185900 | No |
1496 | 5183 | 1727.7 | 140.57 | 46.9 | trimAl: a tool for automated alignment trimming in large-scale phylogenetic analyses. | Salvador Capella-Gutiérrez, José M Silla-Martínez, Toni Gabaldón | Bioinformatics | 2009 | 19505945 | Yes |
1497 | 3455 | 1727.5 | 79.85 | 39.9 | The incidence of congenital heart disease. | Julien I E Hoffman, Samuel Kaplan | J Am Coll Cardiol | 2002 | 12084585 | No |
1498 | 1727 | 1727.0 | 60.68 | 60.7 | Changes in the visual system of monocularly sutured or enucleated cats demonstrable with cytochrome oxidase histochemistry. | M Wong-Riley | Brain Res | 1979 | 223730 | Yes |
1499 | 1727 | 1727.0 | 37.5 | 37.5 | Determination of free amino groups in proteins by trinitrobenzenesulfonic acid. | A F Habeeb | Anal Biochem | 1966 | 4161471 | Yes |
1500 | 1727 | 1727.0 | 0.0 | 0.0 | The recurrence of intracranial meningiomas after surgical treatment. | D Simpson | J Neurol Neurosurg Psychiatry | 1957 | 13406590 | Yes |
1501 | 1727 | 1727.0 | 118.98 | 119.0 | High-performance medicine: the convergence of human and artificial intelligence. | Eric J Topol | Nat Med | 2019 | 30617339 | No |
1502 | 3452 | 1726.0 | 82.5 | 41.2 | Origins and Mechanisms of miRNAs and siRNAs. | Richard W Carthew, Erik J Sontheimer | Cell | 2009 | 19239886 | No |
1503 | 1725 | 1725.0 | 49.77 | 49.8 | Risk and safety of repetitive transcranial magnetic stimulation: report and suggested guidelines from the International Workshop on the Safety of Repetitive Transcranial Magnetic Stimulation, June 5-7, 1996. | E M Wassermann | Electroencephalogr Clin Neurophysiol | 1998 | 9474057 | No |
1504 | 3450 | 1725.0 | 78.75 | 39.4 | Shared principles in NF-kappaB signaling. | Matthew S Hayden, Sankar Ghosh | Cell | 2008 | 18267068 | No |
1505 | 1723 | 1723.0 | 59.59 | 59.6 | Falls in older people: epidemiology, risk factors and strategies for prevention. | Laurence Z Rubenstein | Age Ageing | 2006 | 16926202 | No |
1506 | 5167 | 1722.3 | 117.04 | 39.0 | Inflammation and atherosclerosis. | Peter Libby, Paul M Ridker, Attilio Maseri | Circulation | 2002 | 11877368 | No |
1507 | 1722 | 1722.0 | 0.0 | 0.0 | The general adaptation syndrome and the diseases of adaptation. | H Selye | J Clin Endocrinol Metab | 1946 | 21025115 | Yes |
1508 | 1721 | 1721.0 | 56.22 | 56.2 | Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli. | E M Witkin | Bacteriol Rev | 1976 | 795416 | No |
1509 | 3442 | 1721.0 | 176.83 | 88.4 | Interrater reliability of a modified Ashworth scale of muscle spasticity. | R W Bohannon, M B Smith | Phys Ther | 1987 | 3809245 | Yes |
1510 | 1721 | 1721.0 | 42.77 | 42.8 | Cellular basis of working memory. | P S Goldman-Rakic | Neuron | 1995 | 7695894 | No |
1511 | 5161 | 1720.3 | 229.81 | 76.6 | Some statistical methods useful in circulation research. | S Wallenstein, C L Zucker, J L Fleiss | Circ Res | 1980 | 7379260 | Yes |
1512 | 3440 | 1720.0 | 108.98 | 54.5 | Genome editing. The new frontier of genome engineering with CRISPR-Cas9. | Jennifer A Doudna, Emmanuelle Charpentier | Science | 2014 | 25430774 | No |
1513 | 1719 | 1719.0 | 43.78 | 43.8 | The smooth muscle cell. II. Growth of smooth muscle in culture and formation of elastic fibers. | R Ross | J Cell Biol | 1971 | 4327464 | Yes |
1514 | 1719 | 1719.0 | 52.11 | 52.1 | Genetic differentiation and estimation of gene flow from F-statistics under isolation by distance. | F Rousset | Genetics | 1997 | 9093870 | Yes |
1515 | 1719 | 1719.0 | 51.72 | 51.7 | Aging, cellular senescence, and cancer. | Judith Campisi | Annu Rev Physiol | 2013 | 23140366 | No |
1516 | 1718 | 1718.0 | 33.36 | 33.4 | Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. | Judith Campisi | Cell | 2005 | 15734683 | No |
1517 | 3434 | 1717.0 | 124.87 | 62.4 | The integrative review: updated methodology. | Robin Whittemore, Kathleen Knafl | J Adv Nurs | 2005 | 16268861 | Yes |
1518 | 1716 | 1716.0 | 64.56 | 64.6 | Modeling and variable selection in epidemiologic analysis. | S Greenland | Am J Public Health | 1989 | 2916724 | Yes |
1519 | 10294 | 1715.7 | 312.49 | 52.1 | New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. | Stéphane Guindon, Jean-François Dufayard, Vincent Lefort, Maria Anisimova, Wim Hordijk, Olivier Gascuel | Syst Biol | 2010 | 20525638 | Yes |
1520 | 1714 | 1714.0 | 56.93 | 56.9 | Microalbuminuria predicts clinical proteinuria and early mortality in maturity-onset diabetes. | C E Mogensen | N Engl J Med | 1984 | 6690964 | Yes |
1521 | 5141 | 1713.7 | 161.13 | 53.7 | Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. | H Esterbauer, R J Schaur, H Zollner | Free Radic Biol Med | 1991 | 1937131 | No |
1522 | 3427 | 1713.5 | 0.0 | 0.0 | Convergent and discriminant validation by the multitrait-multimethod matrix. | D T Campbell, D W Fiske | Psychol Bull | 1959 | 13634291 | Yes |
1523 | 3427 | 1713.5 | 87.02 | 43.5 | Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. | Steven E Nissen, Kathy Wolski | N Engl J Med | 2007 | 17517853 | Yes |
1524 | 1713 | 1713.0 | 44.58 | 44.6 | Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli. | G C Walker | Microbiol Rev | 1984 | 6371470 | No |
1525 | 3425 | 1712.5 | 83.12 | 41.6 | The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. | A E Bolton, W M Hunter | Biochem J | 1973 | 4733239 | Yes |
1526 | 3423 | 1711.5 | 86.49 | 43.2 | Quantum dot bioconjugates for ultrasensitive nonisotopic detection. | W C Chan, S Nie | Science | 1998 | 9748158 | Yes |
1527 | 1711 | 1711.0 | 40.38 | 40.4 | The relationship between the spleen colony-forming cell and the haemopoietic stem cell. | R Schofield | Blood Cells | 1978 | 747780 | Yes |
1528 | 1711 | 1711.0 | 40.89 | 40.9 | Tricine-SDS-PAGE. | Hermann Schägger | Nat Protoc | 2006 | 17406207 | Yes |
1529 | 1711 | 1711.0 | 39.05 | 39.0 | Tumor angiogenesis. | Robert S Kerbel | N Engl J Med | 2008 | 18463380 | No |
1530 | 3420 | 1710.0 | 146.92 | 73.5 | A standardized set of 260 pictures: norms for name agreement, image agreement, familiarity, and visual complexity. | J G Snodgrass, M Vanderwart | J Exp Psychol Hum Learn | 1980 | 7373248 | Yes |
1531 | 3420 | 1710.0 | 111.99 | 56.0 | A "Direct-Coloring" Thiocholine Method For Cholinesterases. | M J Karnovsky, L Roots | J Histochem Cytochem | 1964 | 14187330 | Yes |
1532 | 6837 | 1709.2 | 448.97 | 112.2 | Rayyan-a web and mobile app for systematic reviews. | Mourad Ouzzani, Hossam Hammady, Zbys Fedorowicz, Ahmed Elmagarmid | Syst Rev | 2016 | 27919275 | Yes |
1533 | 1709 | 1709.0 | 31.63 | 31.6 | How eukaryotic transcriptional activators work. | M Ptashne | Nature | 1988 | 3050531 | No |
1534 | 1709 | 1709.0 | 38.56 | 38.6 | Effects of cytochalasin and phalloidin on actin. | J A Cooper | J Cell Biol | 1987 | 3312229 | No |
1535 | 1709 | 1709.0 | 0.0 | 0.0 | Transformation Of Biochemically Deficient Strains Of Bacillus Subtilis By Deoxyribonucleate. | J Spizizen | Proc Natl Acad Sci U S A | 1958 | 16590310 | Yes |
1536 | 1709 | 1709.0 | 32.38 | 32.4 | Network motifs: theory and experimental approaches. | Uri Alon | Nat Rev Genet | 2007 | 17510665 | No |
1537 | 3410 | 1705.0 | 145.4 | 72.7 | A fluorometric method for determination of oxidized and reduced glutathione in tissues. | P J Hissin, R Hilf | Anal Biochem | 1976 | 962076 | Yes |
1538 | 1705 | 1705.0 | 60.84 | 60.8 | Computerized transverse axial scanning (tomography). 1. Description of system. | G N Hounsfield | Br J Radiol | 1973 | 4757352 | Yes |
1539 | 3408 | 1704.0 | 151.9 | 76.0 | Cancer immunotherapy using checkpoint blockade. | Antoni Ribas, Jedd D Wolchok | Science | 2018 | 29567705 | No |
1540 | 3407 | 1703.5 | 129.6 | 64.8 | The three-factor eating questionnaire to measure dietary restraint, disinhibition and hunger. | A J Stunkard, S Messick | J Psychosom Res | 1985 | 3981480 | Yes |
1541 | 6814 | 1703.5 | 143.81 | 36.0 | Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. | E A Jaffe, R L Nachman, C G Becker, C R Minick | J Clin Invest | 1973 | 4355998 | Yes |
1542 | 1703 | 1703.0 | 52.12 | 52.1 | A measure of population subdivision based on microsatellite allele frequencies. | M Slatkin | Genetics | 1995 | 7705646 | Yes |
1543 | 1702 | 1702.0 | 41.45 | 41.5 | Maximum likelihood phylogenetic estimation from DNA sequences with variable rates over sites: approximate methods. | Z Yang | J Mol Evol | 1994 | 7932792 | Yes |
1544 | 3404 | 1702.0 | 73.51 | 36.8 | Fibroblasts in cancer. | Raghu Kalluri, Michael Zeisberg | Nat Rev Cancer | 2006 | 16572188 | No |
1545 | 1702 | 1702.0 | 57.11 | 57.1 | Carboxylate-assisted transition-metal-catalyzed C-H bond functionalizations: mechanism and scope. | Lutz Ackermann | Chem Rev | 2011 | 21391562 | Yes |
1546 | 1701 | 1701.0 | 45.49 | 45.5 | Integrins. | E Ruoslahti | J Clin Invest | 1991 | 1985087 | No |
1547 | 17003 | 1700.3 | 539.69 | 54.0 | The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. | F C Arnett, S M Edworthy, D A Bloch, D J McShane, J F Fries, N S Cooper, L A Healey, S R Kaplan, M H Liang, H S Luthra | Arthritis Rheum | 1988 | 3358796 | Yes |
1548 | 1699 | 1699.0 | 45.04 | 45.0 | THE WATER-WATER CYCLE IN CHLOROPLASTS: Scavenging of Active Oxygens and Dissipation of Excess Photons. | Kozi Asada | Annu Rev Plant Physiol Plant Mol Biol | 1999 | 15012221 | Yes |
1549 | 1699 | 1699.0 | 36.84 | 36.8 | Trastuzumab--mechanism of action and use in clinical practice. | Clifford A Hudis | N Engl J Med | 2007 | 17611206 | No |
1550 | 1697 | 1697.0 | 41.29 | 41.3 | The statistical analysis of enzyme kinetic data. | W W Cleland | Adv Enzymol Relat Areas Mol Biol | 1967 | 4881884 | No |
1551 | 1697 | 1697.0 | 54.94 | 54.9 | Validation of a decisional conflict scale. | A M O'Connor | Med Decis Making | 1995 | 7898294 | Yes |
1552 | 3394 | 1697.0 | 135.58 | 67.8 | Dermatology Life Quality Index (DLQI)--a simple practical measure for routine clinical use. | A Y Finlay, G K Khan | Clin Exp Dermatol | 1994 | 8033378 | Yes |
1553 | 3394 | 1697.0 | 93.68 | 46.8 | Biochemistry of multidrug resistance mediated by the multidrug transporter. | M M Gottesman, I Pastan | Annu Rev Biochem | 1993 | 8102521 | No |
1554 | 1697 | 1697.0 | 38.36 | 38.4 | Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): trends and problems. | S A Bustin | J Mol Endocrinol | 2002 | 12200227 | No |
1555 | 1696 | 1696.0 | 76.91 | 76.9 | The micronucleus test. | W Schmid | Mutat Res | 1975 | 48190 | Yes |
1556 | 1696 | 1696.0 | 38.89 | 38.9 | A graphic method for the determination and presentation of binding parameters in a complex system. | H E Rosenthal | Anal Biochem | 1967 | 6048188 | Yes |
1557 | 1696 | 1696.0 | 37.27 | 37.3 | AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. | D Grahame Hardie | Nat Rev Mol Cell Biol | 2007 | 17712357 | No |
1558 | 13561 | 1695.1 | 574.67 | 71.8 | The SILVA ribosomal RNA gene database project: improved data processing and web-based tools. | Christian Quast, Elmar Pruesse, Pelin Yilmaz, Jan Gerken, Timmy Schweer, Pablo Yarza, Jörg Peplies, Frank Oliver Glöckner | Nucleic Acids Res | 2013 | 23193283 | Yes |
1559 | 1695 | 1695.0 | 40.78 | 40.8 | The molecular genetics of cancer. | J M Bishop | Science | 1987 | 3541204 | No |
1560 | 1695 | 1695.0 | 43.08 | 43.1 | Carbonic anhydrase: chemistry, physiology, and inhibition. | T H Maren | Physiol Rev | 1967 | 4964060 | No |
1561 | 1695 | 1695.0 | 69.68 | 69.7 | Adverse health effects of high-effort/low-reward conditions. | J Siegrist | J Occup Health Psychol | 1996 | 9547031 | No |
1562 | 1695 | 1695.0 | 33.46 | 33.5 | The synaptic vesicle cycle. | Thomas C Sudhof | Annu Rev Neurosci | 2004 | 15217342 | No |
1563 | 1695 | 1695.0 | 69.19 | 69.2 | Whatever next? Predictive brains, situated agents, and the future of cognitive science. | Andy Clark | Behav Brain Sci | 2013 | 23663408 | No |
1564 | 8473 | 1694.6 | 192.88 | 38.6 | Stages of embryonic development of the zebrafish. | C B Kimmel, W W Ballard, S R Kimmel, B Ullmann, T F Schilling | Dev Dyn | 1995 | 8589427 | Yes |
1565 | 8471 | 1694.2 | 210.13 | 42.0 | Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. | Alan S Go, Glenn M Chertow, Dongjie Fan, Charles E McCulloch, Chi-yuan Hsu | N Engl J Med | 2004 | 15385656 | Yes |
1566 | 3388 | 1694.0 | 110.6 | 55.3 | Role of free radicals and catalytic metal ions in human disease: an overview. | B Halliwell, J M Gutteridge | Methods Enzymol | 1990 | 2172697 | No |
1567 | 1694 | 1694.0 | 46.36 | 46.4 | The glomerular permeability determined by dextran clearance using Sephadex gel filtration. | C E Mogensen | Scand J Clin Lab Invest | 1968 | 5637478 | Yes |
1568 | 3385 | 1692.5 | 109.08 | 54.5 | Separate visual pathways for perception and action. | M A Goodale, A D Milner | Trends Neurosci | 1992 | 1374953 | No |
1569 | 1692 | 1692.0 | 65.35 | 65.3 | Selenium and human health. | Margaret P Rayman | Lancet | 2012 | 22381456 | No |
1570 | 1691 | 1691.0 | 68.14 | 68.1 | Negative symptoms in schizophrenia. Definition and reliability. | N C Andreasen | Arch Gen Psychiatry | 1982 | 7165477 | Yes |
1571 | 10143 | 1690.5 | 284.18 | 47.4 | Positional cloning of the mouse obese gene and its human homologue. | Y Zhang, R Proenca, M Maffei, M Barone, L Leopold, J M Friedman | Nature | 1994 | 7984236 | Yes |
1572 | 1690 | 1690.0 | 36.12 | 36.1 | Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. | S L Friedman | J Biol Chem | 2000 | 10644669 | No |
1573 | 5069 | 1689.7 | 111.77 | 37.3 | An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. | J K Eng, A L McCormack, J R Yates | J Am Soc Mass Spectrom | 1994 | 24226387 | Yes |
1574 | 6749 | 1687.2 | 285.2 | 71.3 | An inventory for measuring clinical anxiety: psychometric properties. | A T Beck, N Epstein, G Brown, R A Steer | J Consult Clin Psychol | 1988 | 3204199 | Yes |
1575 | 3373 | 1686.5 | 78.6 | 39.3 | The BCL-2 protein family: opposing activities that mediate cell death. | Richard J Youle, Andreas Strasser | Nat Rev Mol Cell Biol | 2008 | 18097445 | No |
1576 | 1686 | 1686.0 | 31.12 | 31.1 | Cyclin-dependent kinases: engines, clocks, and microprocessors. | D O Morgan | Annu Rev Cell Dev Biol | 1997 | 9442875 | No |
1577 | 1686 | 1686.0 | 53.69 | 53.7 | Receiver operating characteristic curve in diagnostic test assessment. | Jayawant N Mandrekar | J Thorac Oncol | 2010 | 20736804 | No |
1578 | 3372 | 1686.0 | 252.29 | 126.1 | Interactive Tree Of Life (iTOL) v4: recent updates and new developments. | Ivica Letunic, Peer Bork | Nucleic Acids Res | 2019 | 30931475 | Yes |
1579 | 3370 | 1685.0 | 88.03 | 44.0 | Multiple sclerosis. | Alastair Compston, Alasdair Coles | Lancet | 2008 | 18970977 | Yes |
1580 | 3370 | 1685.0 | 93.89 | 46.9 | Protective and pathogenic functions of macrophage subsets. | Peter J Murray, Thomas A Wynn | Nat Rev Immunol | 2011 | 21997792 | No |
1581 | 1684 | 1684.0 | 39.68 | 39.7 | Angiogenesis: an organizing principle for drug discovery? | Judah Folkman | Nat Rev Drug Discov | 2007 | 17396134 | No |
1582 | 1683 | 1683.0 | 59.89 | 59.9 | Amyloid deposits and amyloidosis. The beta-fibrilloses (first of two parts). | G G Glenner | N Engl J Med | 1980 | 6154243 | No |
1583 | 1683 | 1683.0 | 10.1 | 10.1 | Chromatographic Separation Of Human Brain Gangliosides. | L Svennerholm | J Neurochem | 1963 | 14066623 | Yes |
1584 | 5047 | 1682.3 | 130.13 | 43.4 | The rapid generation of mutation data matrices from protein sequences. | D T Jones, W R Taylor, J M Thornton | Comput Appl Biosci | 1992 | 1633570 | Yes |
1585 | 1682 | 1682.0 | 32.34 | 32.3 | Generating samples under a Wright-Fisher neutral model of genetic variation. | Richard R Hudson | Bioinformatics | 2002 | 11847089 | Yes |
1586 | 1682 | 1682.0 | 66.78 | 66.8 | Plastic Embedding Mixtures For Use In Electron Microscopy. | H H Mollenhauer | Stain Technol | 1964 | 14127791 | Yes |
1587 | 3364 | 1682.0 | 101.99 | 51.0 | The pathogenesis of rheumatoid arthritis. | Iain B McInnes, Georg Schett | N Engl J Med | 2011 | 22150039 | No |
1588 | 1681 | 1681.0 | 50.71 | 50.7 | Constructions of masculinity and their influence on men's well-being: a theory of gender and health. | W H Courtenay | Soc Sci Med | 2000 | 10741575 | No |
1589 | 3362 | 1681.0 | 66.82 | 33.4 | An automated method for finding molecular complexes in large protein interaction networks. | Gary D Bader, Christopher W V Hogue | BMC Bioinformatics | 2003 | 12525261 | Yes |
1590 | 1681 | 1681.0 | 0.0 | 0.0 | The theory and applications of the exchange of inert gas at the lungs and tissues. | S S Kety | Pharmacol Rev | 1951 | 14833874 | Yes |
1591 | 3361 | 1680.5 | 80.55 | 40.3 | CAP3: A DNA sequence assembly program. | X Huang, A Madan | Genome Res | 1999 | 10508846 | Yes |
1592 | 8402 | 1680.4 | 285.42 | 57.1 | The hallmarks of aging. | Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer | Cell | 2013 | 23746838 | No |
1593 | 1680 | 1680.0 | 63.02 | 63.0 | Paced auditory serial-addition task: a measure of recovery from concussion. | D M Gronwall | Percept Mot Skills | 1977 | 866038 | Yes |
1594 | 1680 | 1680.0 | 49.46 | 49.5 | Pedigrees of some mutant strains of Escherichia coli K-12. | B J Bachmann | Bacteriol Rev | 1972 | 4568763 | No |
1595 | 1680 | 1680.0 | 32.94 | 32.9 | Hox genes in vertebrate development. | R Krumlauf | Cell | 1994 | 7913880 | No |
1596 | 1680 | 1680.0 | 55.17 | 55.2 | The polyvagal perspective. | Stephen W Porges | Biol Psychol | 2007 | 17049418 | No |
1597 | 3360 | 1680.0 | 83.84 | 41.9 | Protein structure prediction on the Web: a case study using the Phyre server. | Lawrence A Kelley, Michael J E Sternberg | Nat Protoc | 2009 | 19247286 | Yes |
1598 | 1679 | 1679.0 | 38.69 | 38.7 | The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. | D M Kingsley | Genes Dev | 1994 | 8299934 | No |
1599 | 1679 | 1679.0 | 47.19 | 47.2 | The in vitro micronucleus technique. | M Fenech | Mutat Res | 2000 | 11113469 | No |
1600 | 3358 | 1679.0 | 155.83 | 77.9 | The amyloid hypothesis of Alzheimer's disease at 25 years. | Dennis J Selkoe, John Hardy | EMBO Mol Med | 2016 | 27025652 | No |
1601 | 3355 | 1677.5 | 67.27 | 33.6 | A guided tour into subcellular colocalization analysis in light microscopy. | S Bolte, F P Cordelières | J Microsc | 2006 | 17210054 | Yes |
1602 | 8387 | 1677.4 | 320.65 | 64.1 | UCHIME improves sensitivity and speed of chimera detection. | Robert C Edgar, Brian J Haas, Jose C Clemente, Christopher Quince, Rob Knight | Bioinformatics | 2011 | 21700674 | Yes |
1603 | 5031 | 1677.0 | 108.98 | 36.3 | Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. | J E Darnell, I M Kerr, G R Stark | Science | 1994 | 8197455 | No |
1604 | 5030 | 1676.7 | 119.65 | 39.9 | Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. | Prateek Kumar, Steven Henikoff, Pauline C Ng | Nat Protoc | 2009 | 19561590 | Yes |
1605 | 1676 | 1676.0 | 49.18 | 49.2 | Drugs which inhibit prostaglandin biosynthesis. | R J Flower | Pharmacol Rev | 1974 | 4208101 | Yes |
1606 | 3352 | 1676.0 | 341.12 | 170.6 | WHO Declares COVID-19 a Pandemic. | Domenico Cucinotta, Maurizio Vanelli | Acta Biomed | 2020 | 32191675 | Yes |
1607 | 3351 | 1675.5 | 71.64 | 35.8 | The epigenomics of cancer. | Peter A Jones, Stephen B Baylin | Cell | 2007 | 17320506 | No |
1608 | 1675 | 1675.0 | 18.41 | 18.4 | Impulses and Physiological States in Theoretical Models of Nerve Membrane. | R Fitzhugh | Biophys J | 1961 | 19431309 | Yes |
1609 | 1674 | 1674.0 | 34.13 | 34.1 | Neurotrophins and their receptors: a convergence point for many signalling pathways. | Moses V Chao | Nat Rev Neurosci | 2003 | 12671646 | No |
1610 | 5020 | 1673.3 | 131.34 | 43.8 | A neural substrate of prediction and reward. | W Schultz, P Dayan, P R Montague | Science | 1997 | 9054347 | No |
1611 | 1673 | 1673.0 | 58.09 | 58.1 | Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture. | A H Conney | Cancer Res | 1982 | 6814745 | No |
1612 | 3345 | 1672.5 | 69.56 | 34.8 | A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids. | D Wessel, U I Flügge | Anal Biochem | 1984 | 6731838 | Yes |
1613 | 1672 | 1672.0 | 38.92 | 38.9 | A revolution in optical manipulation. | David G Grier | Nature | 2003 | 12917694 | No |
1614 | 3344 | 1672.0 | 50.67 | 25.3 | Determination of the base composition of deoxyribonucleic acid from its thermal denaturation temperature. | J Marmur, P Doty | J Mol Biol | 1962 | 14470099 | Yes |
1615 | 1671 | 1671.0 | 39.89 | 39.9 | Inflammatory bowel disease: etiology and pathogenesis. | C Fiocchi | Gastroenterology | 1998 | 9649475 | No |
1616 | 1671 | 1671.0 | 38.39 | 38.4 | NADPH oxidase: an update. | B M Babior | Blood | 1999 | 10029572 | No |
1617 | 1671 | 1671.0 | 38.53 | 38.5 | PLANT COLD ACCLIMATION: Freezing Tolerance Genes and Regulatory Mechanisms. | Michael F. Thomashow | Annu Rev Plant Physiol Plant Mol Biol | 1999 | 15012220 | Yes |
1618 | 1671 | 1671.0 | 49.65 | 49.6 | phangorn: phylogenetic analysis in R. | Klaus Peter Schliep | Bioinformatics | 2011 | 21169378 | Yes |
1619 | 6682 | 1670.5 | 224.57 | 56.1 | SignalP 4.0: discriminating signal peptides from transmembrane regions. | Thomas Nordahl Petersen, Søren Brunak, Gunnar von Heijne, Henrik Nielsen | Nat Methods | 2011 | 21959131 | Yes |
1620 | 1670 | 1670.0 | 53.78 | 53.8 | Synaptic density in human frontal cortex - developmental changes and effects of aging. | P R Huttenlocher | Brain Res | 1979 | 427544 | Yes |
1621 | 1670 | 1670.0 | 50.31 | 50.3 | Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture. | J A Miller | Cancer Res | 1970 | 4915745 | No |
1622 | 3338 | 1669.0 | 78.98 | 39.5 | The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. | P Angel, M Karin | Biochim Biophys Acta | 1991 | 1751545 | No |
1623 | 3338 | 1669.0 | 78.25 | 39.1 | Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. | Robert Visse, Hideaki Nagase | Circ Res | 2003 | 12730128 | No |
1624 | 1668 | 1668.0 | 52.58 | 52.6 | Metallothionein. | D H Hamer | Annu Rev Biochem | 1986 | 3527054 | No |
1625 | 1668 | 1668.0 | 26.91 | 26.9 | RNA-dependent DNA polymerase in virions of RNA tumour viruses. | D Baltimore | Nature | 1970 | 4316300 | Yes |
1626 | 3336 | 1668.0 | 82.88 | 41.4 | Receptors for purines and pyrimidines. | V Ralevic, G Burnstock | Pharmacol Rev | 1998 | 9755289 | No |
1627 | 5003 | 1667.7 | 163.98 | 54.7 | A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. | J R Le Gall, S Lemeshow, F Saulnier | JAMA | 1993 | 8254858 | Yes |
1628 | 1667 | 1667.0 | 0.0 | 0.0 | Method for the determination of hexosamines in tissues. | N F Boas | J Biol Chem | 1953 | 13117829 | Yes |
1629 | 1667 | 1667.0 | 36.55 | 36.5 | Perceptions of epigenetics. | Adrian Bird | Nature | 2007 | 17522671 | Yes |
1630 | 6665 | 1666.2 | 191.87 | 48.0 | The validity of the Hospital Anxiety and Depression Scale. An updated literature review. | Ingvar Bjelland, Alv A Dahl, Tone Tangen Haug, Dag Neckelmann | J Psychosom Res | 2002 | 11832252 | No |
1631 | 1666 | 1666.0 | 32.33 | 32.3 | Cell cycle checkpoints: preventing an identity crisis. | S J Elledge | Science | 1996 | 8939848 | No |
1632 | 3332 | 1666.0 | 83.87 | 41.9 | Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients. | S Schulman, C Kearon | J Thromb Haemost | 2005 | 15842354 | Yes |
1633 | 3326 | 1663.0 | 217.87 | 108.9 | The structure of coping. | L I Pearlin, C Schooler | J Health Soc Behav | 1978 | 649936 | Yes |
1634 | 6644 | 1661.0 | 152.78 | 38.2 | Use of T7 RNA polymerase to direct expression of cloned genes. | F W Studier, A H Rosenberg, J J Dunn, J W Dubendorff | Methods Enzymol | 1990 | 2199796 | Yes |
1635 | 3321 | 1660.5 | 83.71 | 41.9 | Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene. | M Grunstein, D S Hogness | Proc Natl Acad Sci U S A | 1975 | 1105573 | Yes |
1636 | 3321 | 1660.5 | 97.38 | 48.7 | An information-maximization approach to blind separation and blind deconvolution. | A J Bell, T J Sejnowski | Neural Comput | 1995 | 7584893 | Yes |
1637 | 1659 | 1659.0 | 54.68 | 54.7 | Number of people with glaucoma worldwide. | H A Quigley | Br J Ophthalmol | 1996 | 8695555 | No |
1638 | 1658 | 1658.0 | 44.24 | 44.2 | Synergy, antagonism, and what the chequerboard puts between them. | F C Odds | J Antimicrob Chemother | 2003 | 12805255 | No |
1639 | 3316 | 1658.0 | 86.69 | 43.3 | Regulation of chromatin by histone modifications. | Andrew J Bannister, Tony Kouzarides | Cell Res | 2011 | 21321607 | No |
1640 | 4973 | 1657.7 | 261.45 | 87.1 | Impact of Event Scale: a measure of subjective stress. | M Horowitz, N Wilner, W Alvarez | Psychosom Med | 1979 | 472086 | Yes |
1641 | 1657 | 1657.0 | 48.81 | 48.8 | Classification of inflammatory bowel disease. | J E Lennard-Jones | Scand J Gastroenterol Suppl | 1989 | 2617184 | Yes |
1642 | 9940 | 1656.7 | 203.05 | 33.8 | Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. | A Fire, S Xu, M K Montgomery, S A Kostas, S E Driver, C C Mello | Nature | 1998 | 9486653 | Yes |
1643 | 11595 | 1656.4 | 389.33 | 55.6 | GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. | Gordon H Guyatt, Andrew D Oxman, Gunn E Vist, Regina Kunz, Yngve Falck-Ytter, Pablo Alonso-Coello, Holger J Schünemann | BMJ | 2008 | 18436948 | Yes |
1644 | 4969 | 1656.3 | 196.06 | 65.4 | The MOS 36-Item Short-Form Health Survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. | C A McHorney, J E Ware, A E Raczek | Med Care | 1993 | 8450681 | Yes |
1645 | 8281 | 1656.2 | 64.85 | 13.0 | Studies Of Illness In The Aged. The Index Of Adl: A Standardized Measure Of Biological And Psychosocial Function. | S Katz, A B Ford, R W Moskowitz, B A Jackson, M W Jaffe | JAMA | 1963 | 14044222 | Yes |
1646 | 3312 | 1656.0 | 58.86 | 29.4 | Method for the isolation of intact islets of Langerhans from the rat pancreas. | P E Lacy, M Kostianovsky | Diabetes | 1967 | 5333500 | Yes |
1647 | 1656 | 1656.0 | 35.99 | 36.0 | The NCI60 human tumour cell line anticancer drug screen. | Robert H Shoemaker | Nat Rev Cancer | 2006 | 16990858 | No |
1648 | 6622 | 1655.5 | 190.71 | 47.7 | Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. | B Biswal, F Z Yetkin, V M Haughton, J S Hyde | Magn Reson Med | 1995 | 8524021 | Yes |
1649 | 3311 | 1655.5 | 94.23 | 47.1 | Astrocytes: biology and pathology. | Michael V Sofroniew, Harry V Vinters | Acta Neuropathol | 2010 | 20012068 | No |
1650 | 1655 | 1655.0 | 46.9 | 46.9 | The many roles for fluorine in medicinal chemistry. | William K Hagmann | J Med Chem | 2008 | 18570365 | Yes |
1651 | 1655 | 1655.0 | 52.62 | 52.6 | Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances. | Joseph J Volpe | Lancet Neurol | 2009 | 19081519 | No |
1652 | 3307 | 1653.5 | 87.45 | 43.7 | Integrating QTL mapping and genome scans towards the characterization of candidate loci under parallel selection in the lake whitefish (Coregonus clupeaformis). | S M Rogers, L Bernatchez | Mol Ecol | 2005 | 15660930 | Yes |
1653 | 1653 | 1653.0 | 66.13 | 66.1 | Sample size in qualitative research. | M Sandelowski | Res Nurs Health | 1995 | 7899572 | Yes |
1654 | 1653 | 1653.0 | 0.0 | 0.0 | Axo-somatic and axo-dendritic synapses of the cerebral cortex: an electron microscope study. | E G Gray | J Anat | 1959 | 13829103 | Yes |
1655 | 1653 | 1653.0 | 37.05 | 37.0 | Introduction to NF-kappaB: players, pathways, perspectives. | T D Gilmore | Oncogene | 2006 | 17072321 | No |
1656 | 1652 | 1652.0 | 41.9 | 41.9 | Neurotrophins and neuronal plasticity. | H Thoenen | Science | 1995 | 7570017 | No |
1657 | 3304 | 1652.0 | 121.05 | 60.5 | The Carbon Monoxide-Binding Pigment Of Liver Microsomes. Ii. Solubilization, Purification, And Properties. | T Omura, R Sato | J Biol Chem | 1964 | 14209972 | Yes |
1658 | 3303 | 1651.5 | 66.88 | 33.4 | A general framework for weighted gene co-expression network analysis. | Bin Zhang, Steve Horvath | Stat Appl Genet Mol Biol | 2005 | 16646834 | Yes |
1659 | 6604 | 1651.0 | 261.33 | 65.3 | 16S ribosomal DNA amplification for phylogenetic study. | W G Weisburg, S M Barns, D A Pelletier, D J Lane | J Bacteriol | 1991 | 1987160 | Yes |
1660 | 1651 | 1651.0 | 44.4 | 44.4 | An improved procedure for serum creatine phosphokinase determination. | S B Rosalki | J Lab Clin Med | 1967 | 4381359 | Yes |
1661 | 1650 | 1650.0 | 39.12 | 39.1 | Two pathogenetic types of endometrial carcinoma. | J V Bokhman | Gynecol Oncol | 1983 | 6822361 | Yes |
1662 | 1650 | 1650.0 | 0.0 | 0.0 | Note on the sampling error of the difference between correlated proportions or percentages. | Q McNEMAR | Psychometrika | 1947 | 20254758 | Yes |
1663 | 1649 | 1649.0 | 80.57 | 80.6 | Measuring degree of physical dependence to tobacco smoking with reference to individualization of treatment. | K O Fagerström | Addict Behav | 1978 | 735910 | Yes |
1664 | 1648 | 1648.0 | 33.36 | 33.4 | DNA in a material world. | Nadrian C Seeman | Nature | 2003 | 12540916 | No |
1665 | 1647 | 1647.0 | 42.7 | 42.7 | Alpha-crystallin can function as a molecular chaperone. | J Horwitz | Proc Natl Acad Sci U S A | 1992 | 1438232 | Yes |
1666 | 1647 | 1647.0 | 67.57 | 67.6 | Responses to depression and their effects on the duration of depressive episodes. | S Nolen-Hoeksema | J Abnorm Psychol | 1991 | 1757671 | No |
1667 | 1647 | 1647.0 | 31.21 | 31.2 | Switching and signaling at the telomere. | E H Blackburn | Cell | 2001 | 11572773 | No |
1668 | 3291 | 1645.5 | 122.86 | 61.4 | The mini-mental state examination: a comprehensive review. | T N Tombaugh, N J McIntyre | J Am Geriatr Soc | 1992 | 1512391 | No |
1669 | 1645 | 1645.0 | 67.27 | 67.3 | A comparison of the two one-sided tests procedure and the power approach for assessing the equivalence of average bioavailability. | D J Schuirmann | J Pharmacokinet Biopharm | 1987 | 3450848 | Yes |
1670 | 1645 | 1645.0 | 45.48 | 45.5 | Turnover of inositol phospholipids and signal transduction. | Y Nishizuka | Science | 1984 | 6147898 | No |
1671 | 3289 | 1644.5 | 106.62 | 53.3 | Neurocircuitry of addiction. | George F Koob, Nora D Volkow | Neuropsychopharmacology | 2010 | 19710631 | No |
1672 | 1644 | 1644.0 | 46.46 | 46.5 | Semiempirical hybrid density functional with perturbative second-order correlation. | Stefan Grimme | J Chem Phys | 2006 | 16438568 | Yes |
1673 | 1644 | 1644.0 | 45.11 | 45.1 | The origins of the developmental origins theory. | D J P Barker | J Intern Med | 2007 | 17444880 | No |
1674 | 1644 | 1644.0 | 47.07 | 47.1 | Optimization of parameters for semiempirical methods V: modification of NDDO approximations and application to 70 elements. | James J P Stewart | J Mol Model | 2007 | 17828561 | Yes |
1675 | 1643 | 1643.0 | 19.62 | 19.6 | Amino acid difference formula to help explain protein evolution. | R Grantham | Science | 1974 | 4843792 | Yes |
1676 | 3286 | 1643.0 | 66.48 | 33.2 | Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. | Gary L Johnson, Razvan Lapadat | Science | 2002 | 12471242 | No |
1677 | 1643 | 1643.0 | 30.56 | 30.6 | Neuroblastoma: biological insights into a clinical enigma. | Garrett M Brodeur | Nat Rev Cancer | 2003 | 12612655 | No |
1678 | 3284 | 1642.0 | 66.0 | 33.0 | Upstream and downstream of mTOR. | Nissim Hay, Nahum Sonenberg | Genes Dev | 2004 | 15314020 | No |
1679 | 3283 | 1641.5 | 71.13 | 35.6 | Protein structure comparison by alignment of distance matrices. | L Holm, C Sander | J Mol Biol | 1993 | 8377180 | Yes |
1680 | 1641 | 1641.0 | 49.01 | 49.0 | Extracellular ATP: effects, sources and fate. | J L Gordon | Biochem J | 1986 | 3006665 | No |
1681 | 1641 | 1641.0 | 39.14 | 39.1 | The failing heart--an engine out of fuel. | Stefan Neubauer | N Engl J Med | 2007 | 17360992 | No |
1682 | 6559 | 1639.8 | 202.51 | 50.6 | The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. | S P Baker, B O'Neill, W Haddon, W B Long | J Trauma | 1974 | 4814394 | Yes |
1683 | 1639 | 1639.0 | 53.79 | 53.8 | Archaea in coastal marine environments. | E F DeLong | Proc Natl Acad Sci U S A | 1992 | 1608980 | Yes |
1684 | 1639 | 1639.0 | 32.46 | 32.5 | Simple memory: a theory for archicortex. | D Marr | Philos Trans R Soc Lond B Biol Sci | 1971 | 4399412 | Yes |
1685 | 1639 | 1639.0 | 40.34 | 40.3 | Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia. | Shitij Kapur | Am J Psychiatry | 2003 | 12505794 | No |
1686 | 1638 | 1638.0 | 37.45 | 37.5 | In vivo near-infrared fluorescence imaging. | John V Frangioni | Curr Opin Chem Biol | 2003 | 14580568 | No |
1687 | 1638 | 1638.0 | 53.07 | 53.1 | The global impact of pre-eclampsia and eclampsia. | Lelia Duley | Semin Perinatol | 2009 | 19464502 | No |
1688 | 1637 | 1637.0 | 62.68 | 62.7 | Probiotics in man and animals. | R Fuller | J Appl Bacteriol | 1989 | 2666378 | No |
1689 | 1637 | 1637.0 | 37.93 | 37.9 | A simple fluorimetric method for the estimation of free 11-hydroxycorticoids in human plasma. | D Mattingly | J Clin Pathol | 1962 | 14471419 | Yes |
1690 | 1636 | 1636.0 | 34.7 | 34.7 | Neuronal calcium signaling. | M J Berridge | Neuron | 1998 | 9697848 | No |
1691 | 1636 | 1636.0 | 50.73 | 50.7 | Stress and disorders of the stress system. | George P Chrousos | Nat Rev Endocrinol | 2009 | 19488073 | No |
1692 | 3269 | 1634.5 | 74.72 | 37.4 | Human mesenchymal stem cells modulate allogeneic immune cell responses. | Sudeepta Aggarwal, Mark F Pittenger | Blood | 2005 | 15494428 | Yes |
1693 | 1634 | 1634.0 | 58.46 | 58.5 | Dual-task interference in simple tasks: data and theory. | H Pashler | Psychol Bull | 1994 | 7972591 | No |
1694 | 1634 | 1634.0 | 35.49 | 35.5 | Hematopoietic stem-cell transplantation. | Edward A Copelan | N Engl J Med | 2006 | 16641398 | No |
1695 | 3268 | 1634.0 | 91.17 | 45.6 | A perspective on cancer cell metastasis. | Christine L Chaffer, Robert A Weinberg | Science | 2011 | 21436443 | No |
1696 | 3266 | 1633.0 | 212.12 | 106.1 | A clinical method of functional assessment of the shoulder. | C R Constant, A H Murley | Clin Orthop Relat Res | 1987 | 3791738 | Yes |
1697 | 3265 | 1632.5 | 98.95 | 49.5 | The benefits of being present: mindfulness and its role in psychological well-being. | Kirk Warren Brown, Richard M Ryan | J Pers Soc Psychol | 2003 | 12703651 | Yes |
1698 | 1632 | 1632.0 | 71.12 | 71.1 | Neurogenetic adaptive mechanisms in alcoholism. | C R Cloninger | Science | 1987 | 2882604 | Yes |
1699 | 1632 | 1632.0 | 30.56 | 30.6 | Germinal centers. | I C MacLennan | Annu Rev Immunol | 1994 | 8011279 | No |
1700 | 1632 | 1632.0 | 40.16 | 40.2 | Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. | M J Meaney | Annu Rev Neurosci | 2001 | 11520931 | No |
1701 | 1632 | 1632.0 | 35.33 | 35.3 | An approximately unbiased test of phylogenetic tree selection. | Hidetoshi Shimodaira | Syst Biol | 2002 | 12079646 | Yes |
1702 | 1632 | 1632.0 | 41.75 | 41.8 | Understanding biofilm resistance to antibacterial agents. | David Davies | Nat Rev Drug Discov | 2003 | 12563302 | No |
1703 | 1631 | 1631.0 | 56.42 | 56.4 | Frontal-subcortical circuits and human behavior. | J L Cummings | Arch Neurol | 1993 | 8352676 | No |
1704 | 1631 | 1631.0 | 29.16 | 29.2 | Maximum-likelihood density modification. | T C Terwilliger | Acta Crystallogr D Biol Crystallogr | 2000 | 10944333 | Yes |
1705 | 3260 | 1630.0 | 77.19 | 38.6 | Adipose tissue as an endocrine organ. | Erin E Kershaw, Jeffrey S Flier | J Clin Endocrinol Metab | 2004 | 15181022 | No |
1706 | 1629 | 1629.0 | 58.26 | 58.3 | Cell damage in the brain: a speculative synthesis. | B K Siesjö | J Cereb Blood Flow Metab | 1981 | 6276420 | No |
1707 | 1629 | 1629.0 | 34.81 | 34.8 | Bone morphogenetic proteins: multifunctional regulators of vertebrate development. | B L Hogan | Genes Dev | 1996 | 8682290 | No |
1708 | 1629 | 1629.0 | 30.35 | 30.4 | Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy. | M G Gustafsson | J Microsc | 2000 | 10810003 | Yes |
1709 | 3257 | 1628.5 | 129.91 | 65.0 | The Emerging Hallmarks of Cancer Metabolism. | Natalya N Pavlova, Craig B Thompson | Cell Metab | 2016 | 26771115 | No |
1710 | 9768 | 1628.0 | 226.78 | 37.8 | Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. | D J Slamon, G M Clark, S G Wong, W J Levin, A Ullrich, W L McGuire | Science | 1987 | 3798106 | Yes |
1711 | 1628 | 1628.0 | 72.48 | 72.5 | Mood and memory. | G H Bower | Am Psychol | 1981 | 7224324 | Yes |
1712 | 4883 | 1627.7 | 208.18 | 69.4 | The behaviour change wheel: a new method for characterising and designing behaviour change interventions. | Susan Michie, Maartje M van Stralen, Robert West | Implement Sci | 2011 | 21513547 | No |
1713 | 3252 | 1626.0 | 85.27 | 42.6 | Early identification of refractory epilepsy. | P Kwan, M J Brodie | N Engl J Med | 2000 | 10660394 | Yes |
1714 | 1626 | 1626.0 | 23.13 | 23.1 | Structural considerations in the interaction of DNA and acridines. | L S Lerman | J Mol Biol | 1961 | 13761054 | Yes |
1715 | 1626 | 1626.0 | 38.45 | 38.5 | Five rules for the evolution of cooperation. | Martin A Nowak | Science | 2006 | 17158317 | No |
1716 | 6502 | 1625.5 | 280.39 | 70.1 | A rating scale for mania: reliability, validity and sensitivity. | R C Young, J T Biggs, V E Ziegler, D A Meyer | Br J Psychiatry | 1978 | 728692 | Yes |
1717 | 1625 | 1625.0 | 42.57 | 42.6 | Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp. | D A Dougherty | Science | 1996 | 8539615 | No |
1718 | 11370 | 1624.3 | 339.67 | 48.5 | AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility. | Garrett M Morris, Ruth Huey, William Lindstrom, Michel F Sanner, Richard K Belew, David S Goodsell, Arthur J Olson | J Comput Chem | 2009 | 19399780 | Yes |
1719 | 1624 | 1624.0 | 46.07 | 46.1 | Fluorescence energy transfer as a spectroscopic ruler. | L Stryer | Annu Rev Biochem | 1978 | 354506 | No |
1720 | 1624 | 1624.0 | 49.04 | 49.0 | Stress signalling pathways that impair prefrontal cortex structure and function. | Amy F T Arnsten | Nat Rev Neurosci | 2009 | 19455173 | No |
1721 | 3247 | 1623.5 | 87.88 | 43.9 | Bronchopulmonary dysplasia. | A H Jobe, E Bancalari | Am J Respir Crit Care Med | 2001 | 11401896 | No |
1722 | 3247 | 1623.5 | 110.0 | 55.0 | Neutrophil recruitment and function in health and inflammation. | Elzbieta Kolaczkowska, Paul Kubes | Nat Rev Immunol | 2013 | 23435331 | No |
1723 | 1623 | 1623.0 | 33.07 | 33.1 | Structural features in eukaryotic mRNAs that modulate the initiation of translation. | M Kozak | J Biol Chem | 1991 | 1939050 | No |
1724 | 1623 | 1623.0 | 46.3 | 46.3 | The basal ganglia: focused selection and inhibition of competing motor programs. | J W Mink | Prog Neurobiol | 1996 | 9004351 | No |
1725 | 1623 | 1623.0 | 34.28 | 34.3 | The caveolae membrane system. | R G Anderson | Annu Rev Biochem | 1998 | 9759488 | No |
1726 | 1622 | 1622.0 | 45.21 | 45.2 | Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction. | B Hille | J Gen Physiol | 1977 | 300786 | Yes |
1727 | 1622 | 1622.0 | 50.87 | 50.9 | Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage. | D W Choi | Trends Neurosci | 1988 | 2469166 | No |
1728 | 3243 | 1621.5 | 96.75 | 48.4 | Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltons. | M Karas, F Hillenkamp | Anal Chem | 1988 | 3239801 | Yes |
1729 | 12970 | 1621.2 | 377.11 | 47.1 | The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. | Ziad S Nasreddine, Natalie A Phillips, Valérie Bédirian, Simon Charbonneau, Victor Whitehead, Isabelle Collin, Jeffrey L Cummings, Howard Chertkow | J Am Geriatr Soc | 2005 | 15817019 | Yes |
1730 | 1621 | 1621.0 | 58.02 | 58.0 | The linear-quadratic formula and progress in fractionated radiotherapy. | J F Fowler | Br J Radiol | 1989 | 2670032 | No |
1731 | 4863 | 1621.0 | 147.14 | 49.0 | Simultaneous inference in general parametric models. | Torsten Hothorn, Frank Bretz, Peter Westfall | Biom J | 2008 | 18481363 | No |
1732 | 1619 | 1619.0 | 47.3 | 47.3 | Metalloproteinases and their inhibitors in matrix remodeling. | L M Matrisian | Trends Genet | 1990 | 2132731 | No |
1733 | 1619 | 1619.0 | 27.7 | 27.7 | Cell cycle checkpoint signaling through the ATM and ATR kinases. | R T Abraham | Genes Dev | 2001 | 11544175 | No |
1734 | 3236 | 1618.0 | 76.62 | 38.3 | Rapid and sensitive protein similarity searches. | D J Lipman, W R Pearson | Science | 1985 | 2983426 | Yes |
1735 | 1618 | 1618.0 | 41.17 | 41.2 | The importance of the ratio of omega-6/omega-3 essential fatty acids. | A P Simopoulos | Biomed Pharmacother | 2002 | 12442909 | No |
1736 | 4853 | 1617.7 | 94.84 | 31.6 | T-Coffee: A novel method for fast and accurate multiple sequence alignment. | C Notredame, D G Higgins, J Heringa | J Mol Biol | 2000 | 10964570 | Yes |
1737 | 1617 | 1617.0 | 36.94 | 36.9 | VLA proteins in the integrin family: structures, functions, and their role on leukocytes. | M E Hemler | Annu Rev Immunol | 1990 | 2188667 | No |
1738 | 9700 | 1616.7 | 335.1 | 55.9 | Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. | L C Green, D A Wagner, J Glogowski, P L Skipper, J S Wishnok, S R Tannenbaum | Anal Biochem | 1982 | 7181105 | Yes |
1739 | 1616 | 1616.0 | 57.79 | 57.8 | Aging, natural death, and the compression of morbidity. | J F Fries | N Engl J Med | 1980 | 7383070 | Yes |
1740 | 1616 | 1616.0 | 0.0 | 0.0 | Discharge patterns and functional organization of mammalian retina. | S W Kuffler | J Neurophysiol | 1953 | 13035466 | Yes |
1741 | 3229 | 1614.5 | 95.29 | 47.6 | Unified approach for molecular dynamics and density-functional theory. | R Car, M Parrinello | Phys Rev Lett | 1985 | 10032153 | Yes |
1742 | 1614 | 1614.0 | 58.52 | 58.5 | Interhemispheric differences in the localization of psychological processes in man. | B Milner | Br Med Bull | 1971 | 4937273 | No |
1743 | 1614 | 1614.0 | 71.35 | 71.3 | The structure and properties of the sense of coherence scale. | A Antonovsky | Soc Sci Med | 1993 | 8480217 | Yes |
1744 | 3228 | 1614.0 | 89.11 | 44.6 | Diarrheagenic Escherichia coli. | J P Nataro, J B Kaper | Clin Microbiol Rev | 1998 | 9457432 | No |
1745 | 1613 | 1613.0 | 36.93 | 36.9 | Cellular oncogenes and retroviruses. | J M Bishop | Annu Rev Biochem | 1983 | 6351725 | No |
1746 | 3225 | 1612.5 | 85.9 | 43.0 | Molecular mechanisms of long noncoding RNAs. | Kevin C Wang, Howard Y Chang | Mol Cell | 2011 | 21925379 | No |
1747 | 6449 | 1612.2 | 212.9 | 53.2 | Common method biases in behavioral research: a critical review of the literature and recommended remedies. | Philip M Podsakoff, Scott B MacKenzie, Jeong-Yeon Lee, Nathan P Podsakoff | J Appl Psychol | 2003 | 14516251 | No |
1748 | 4834 | 1611.3 | 176.59 | 58.9 | Multiple imputation using chained equations: Issues and guidance for practice. | Ian R White, Patrick Royston, Angela M Wood | Stat Med | 2011 | 21225900 | Yes |
1749 | 1611 | 1611.0 | 30.49 | 30.5 | Protein kinases--the major drug targets of the twenty-first century? | Philip Cohen | Nat Rev Drug Discov | 2002 | 12120282 | No |
1750 | 3222 | 1611.0 | 81.94 | 41.0 | ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins. | Markus Wiederstein, Manfred J Sippl | Nucleic Acids Res | 2007 | 17517781 | Yes |
1751 | 1611 | 1611.0 | 45.43 | 45.4 | Understanding organofluorine chemistry. An introduction to the C-F bond. | David O'Hagan | Chem Soc Rev | 2008 | 18197347 | No |
1752 | 1610 | 1610.0 | 51.04 | 51.0 | Cellular defenses against damage from reactive oxygen species. | B P Yu | Physiol Rev | 1994 | 8295932 | No |
1753 | 1610 | 1610.0 | 49.75 | 49.8 | Apoptosis in cancer: from pathogenesis to treatment. | Rebecca S Y Wong | J Exp Clin Cancer Res | 2011 | 21943236 | No |
1754 | 3217 | 1608.5 | 62.58 | 31.3 | Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. | M E Greenberg, E B Ziff | Nature | 1984 | 6090941 | Yes |
1755 | 1608 | 1608.0 | 39.22 | 39.2 | Recognition of errors in three-dimensional structures of proteins. | M J Sippl | Proteins | 1993 | 8108378 | Yes |
1756 | 1607 | 1607.0 | 39.51 | 39.5 | Tumor necrosis factor (TNF). | L J Old | Science | 1985 | 2413547 | Yes |
1757 | 1606 | 1606.0 | 45.55 | 45.5 | Ionic dependence of glutamate neurotoxicity. | D W Choi | J Neurosci | 1987 | 2880938 | Yes |
1758 | 1606 | 1606.0 | 40.65 | 40.6 | External validity of randomised controlled trials: "to whom do the results of this trial apply?". | Peter M Rothwell | Lancet | 2005 | 15639683 | Yes |
1759 | 1604 | 1604.0 | 81.22 | 81.2 | Hydrogel: Preparation, characterization, and applications: A review. | Enas M Ahmed | J Adv Res | 2015 | 25750745 | No |
1760 | 1604 | 1604.0 | 221.62 | 221.6 | COVID-19 and mental health: A review of the existing literature. | Ravi Philip Rajkumar | Asian J Psychiatr | 2020 | 32302935 | Yes |
1761 | 1603 | 1603.0 | 56.74 | 56.7 | The case-crossover design: a method for studying transient effects on the risk of acute events. | M Maclure | Am J Epidemiol | 1991 | 1985444 | Yes |
1762 | 1603 | 1603.0 | 0.0 | 0.0 | Application of a Theory of Enzyme Specificity to Protein Synthesis. | D E Koshland | Proc Natl Acad Sci U S A | 1958 | 16590179 | Yes |
1763 | 3206 | 1603.0 | 152.1 | 76.0 | Making sense of Cronbach's alpha. | Mohsen Tavakol, Reg Dennick | Int J Med Educ | 2011 | 28029643 | No |
1764 | 3205 | 1602.5 | 114.01 | 57.0 | Measuring emotion: the Self-Assessment Manikin and the Semantic Differential. | M M Bradley, P J Lang | J Behav Ther Exp Psychiatry | 1994 | 7962581 | Yes |
1765 | 3204 | 1602.0 | 67.14 | 33.6 | The Ki-67 protein: from the known and the unknown. | T Scholzen, J Gerdes | J Cell Physiol | 2000 | 10653597 | No |
1766 | 3202 | 1601.0 | 112.87 | 56.4 | Avoiding false positives with PCR. | S Kwok, R Higuchi | Nature | 1989 | 2716852 | Yes |
1767 | 1601 | 1601.0 | 46.04 | 46.0 | The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system function. | R R Llinás | Science | 1988 | 3059497 | No |
1768 | 1601 | 1601.0 | 33.41 | 33.4 | The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept. | A G Pearse | J Histochem Cytochem | 1969 | 4143745 | No |
1769 | 1601 | 1601.0 | 0.0 | 0.0 | Antigen-antibody reactions in gels. IV. Types of reactions in coordinated systems of diffusion. | O Ouchterlony | Acta Pathol Microbiol Scand | 1953 | 13079779 | Yes |
1770 | 1601 | 1601.0 | 0.0 | 0.0 | Cerebral blood flow and oxygen consumption in man. | N A Lassen | Physiol Rev | 1959 | 13645234 | Yes |
1771 | 1601 | 1601.0 | 30.96 | 31.0 | The microRNA Registry. | Sam Griffiths-Jones | Nucleic Acids Res | 2004 | 14681370 | Yes |
1772 | 3201 | 1600.5 | 67.64 | 33.8 | Inhibitors of mammalian G1 cyclin-dependent kinases. | C J Sherr, J M Roberts | Genes Dev | 1995 | 7758941 | No |
1773 | 1600 | 1600.0 | 40.62 | 40.6 | Molecular biology of prion diseases. | S B Prusiner | Science | 1991 | 1675487 | No |
1774 | 1600 | 1600.0 | 31.64 | 31.6 | An analysis of vertebrate mRNA sequences: intimations of translational control. | M Kozak | J Cell Biol | 1991 | 1955461 | No |
1775 | 3200 | 1600.0 | 66.12 | 33.1 | Signaling to NF-kappaB. | Matthew S Hayden, Sankar Ghosh | Genes Dev | 2004 | 15371334 | No |
1776 | 4799 | 1599.7 | 133.11 | 44.4 | Cell death: the significance of apoptosis. | A H Wyllie, J F Kerr, A R Currie | Int Rev Cytol | 1980 | 7014501 | No |
1777 | 3199 | 1599.5 | 63.97 | 32.0 | The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat. | J O'Keefe, J Dostrovsky | Brain Res | 1971 | 5124915 | Yes |
1778 | 3199 | 1599.5 | 61.79 | 30.9 | Automated MAD and MIR structure solution. | T C Terwilliger, J Berendzen | Acta Crystallogr D Biol Crystallogr | 1999 | 10089316 | Yes |
1779 | 1599 | 1599.0 | 44.45 | 44.5 | Multiple imputation of discrete and continuous data by fully conditional specification. | Stef van Buuren | Stat Methods Med Res | 2007 | 17621469 | Yes |
1780 | 1599 | 1599.0 | 57.09 | 57.1 | Cytokines in inflammatory bowel disease. | Markus F Neurath | Nat Rev Immunol | 2014 | 24751956 | No |
1781 | 1598 | 1598.0 | 34.23 | 34.2 | On finding all suboptimal foldings of an RNA molecule. | M Zuker | Science | 1989 | 2468181 | No |
1782 | 3196 | 1598.0 | 88.57 | 44.3 | Polyamines. | C W Tabor, H Tabor | Annu Rev Biochem | 1984 | 6206782 | No |
1783 | 1598 | 1598.0 | 41.82 | 41.8 | Task switching. | Stephen Monsell | Trends Cogn Sci | 2003 | 12639695 | Yes |
1784 | 4794 | 1598.0 | 114.28 | 38.1 | Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets. | Claus Lindbjerg Andersen, Jens Ledet Jensen, Torben Falck Ørntoft | Cancer Res | 2004 | 15289330 | Yes |
1785 | 1597 | 1597.0 | 52.05 | 52.0 | Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue'). | M N Marsh | Gastroenterology | 1992 | 1727768 | No |
1786 | 1597 | 1597.0 | 44.82 | 44.8 | Gold-catalyzed organic reactions. | A Stephen K Hashmi | Chem Rev | 2007 | 17580975 | Yes |
1787 | 1597 | 1597.0 | 53.05 | 53.0 | Asthma phenotypes: the evolution from clinical to molecular approaches. | Sally E Wenzel | Nat Med | 2012 | 22561835 | No |
1788 | 3194 | 1597.0 | 156.34 | 78.2 | Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees. | Ivica Letunic, Peer Bork | Nucleic Acids Res | 2016 | 27095192 | Yes |
1789 | 1596 | 1596.0 | 36.2 | 36.2 | Thiazolidinediones. | Hannele Yki-Järvinen | N Engl J Med | 2004 | 15356308 | No |
1790 | 3191 | 1595.5 | 83.36 | 41.7 | Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. | D B Dill, D L Costill | J Appl Physiol | 1974 | 4850854 | Yes |
1791 | 1595 | 1595.0 | 72.63 | 72.6 | Measurement of health state utilities for economic appraisal. | G W Torrance | J Health Econ | 1986 | 10311607 | No |
1792 | 1595 | 1595.0 | 36.42 | 36.4 | Getting formal with dopamine and reward. | Wolfram Schultz | Neuron | 2002 | 12383780 | No |
1793 | 1594 | 1594.0 | 28.76 | 28.8 | Altering the genome by homologous recombination. | M R Capecchi | Science | 1989 | 2660260 | No |
1794 | 1594 | 1594.0 | 70.87 | 70.9 | The contribution of low birth weight to infant mortality and childhood morbidity. | M C McCormick | N Engl J Med | 1985 | 3880598 | No |
1795 | 1594 | 1594.0 | 36.66 | 36.7 | A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. | D A Gewirtz | Biochem Pharmacol | 1999 | 10075079 | No |
1796 | 1594 | 1594.0 | 36.35 | 36.4 | Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. | S C Manolagas | Endocr Rev | 2000 | 10782361 | No |
1797 | 1593 | 1593.0 | 36.68 | 36.7 | Neurovascular regulation in the normal brain and in Alzheimer's disease. | Costantino Iadecola | Nat Rev Neurosci | 2004 | 15100718 | No |
1798 | 1592 | 1592.0 | 38.96 | 39.0 | The corticosteroid receptor hypothesis of depression. | F Holsboer | Neuropsychopharmacology | 2000 | 11027914 | No |
1799 | 3183 | 1591.5 | 77.56 | 38.8 | A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes. | S Tabor, C C Richardson | Proc Natl Acad Sci U S A | 1985 | 3156376 | Yes |
1800 | 3182 | 1591.0 | 91.38 | 45.7 | Oxidative stress, glutamate, and neurodegenerative disorders. | J T Coyle, P Puttfarcken | Science | 1993 | 7901908 | No |
1801 | 1590 | 1590.0 | 31.36 | 31.4 | Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing. | D I Svergun | Biophys J | 1999 | 10354416 | Yes |
1802 | 1590 | 1590.0 | 35.65 | 35.6 | Hypertrophic cardiomyopathy: a systematic review. | Barry J Maron | JAMA | 2002 | 11886323 | No |
1803 | 1589 | 1589.0 | 48.45 | 48.5 | Chlorophyll fluorescence: a probe of photosynthesis in vivo. | Neil R Baker | Annu Rev Plant Biol | 2008 | 18444897 | No |
1804 | 1588 | 1588.0 | 48.75 | 48.8 | Efficient analysis of experimental observations. | W J Dixon | Annu Rev Pharmacol Toxicol | 1980 | 7387124 | Yes |
1805 | 1588 | 1588.0 | 43.91 | 43.9 | Extended-spectrum beta-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat. | P A Bradford | Clin Microbiol Rev | 2001 | 11585791 | No |
1806 | 1587 | 1587.0 | 56.61 | 56.6 | Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons. | P Holzer | Pharmacol Rev | 1991 | 1852779 | No |
1807 | 1587 | 1587.0 | 41.87 | 41.9 | Precision mapping of quantitative trait loci. | Z B Zeng | Genetics | 1994 | 8013918 | Yes |
1808 | 1587 | 1587.0 | 35.57 | 35.6 | The proto-oncogene Bcl-2 and its role in regulating apoptosis. | G Kroemer | Nat Med | 1997 | 9176486 | No |
1809 | 1586 | 1586.0 | 51.79 | 51.8 | Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection. | W H Oldendorf | Am J Physiol | 1971 | 5124307 | Yes |
1810 | 1586 | 1586.0 | 54.93 | 54.9 | The self-medication hypothesis of substance use disorders: a reconsideration and recent applications. | E J Khantzian | Harv Rev Psychiatry | 1997 | 9385000 | No |
1811 | 3171 | 1585.5 | 97.15 | 48.6 | Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. | D S Bredt, S H Snyder | Proc Natl Acad Sci U S A | 1990 | 1689048 | Yes |
1812 | 1585 | 1585.0 | 65.32 | 65.3 | Regulation of noradrenaline release by presynaptic receptor systems. | K Starke | Rev Physiol Biochem Pharmacol | 1977 | 14389 | No |
1813 | 1585 | 1585.0 | 34.33 | 34.3 | Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. | G L Semenza | Annu Rev Cell Dev Biol | 1999 | 10611972 | No |
1814 | 1583 | 1583.0 | 29.45 | 29.4 | How cells read TGF-beta signals. | J Massagué | Nat Rev Mol Cell Biol | 2000 | 11252892 | No |
1815 | 3163 | 1581.5 | 65.87 | 32.9 | Fitting a mixture model by expectation maximization to discover motifs in biopolymers. | T L Bailey, C Elkan | Proc Int Conf Intell Syst Mol Biol | 1994 | 7584402 | Yes |
1816 | 4744 | 1581.3 | 115.69 | 38.6 | Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. | Earl S Ford, Wayne H Giles, William H Dietz | JAMA | 2002 | 11790215 | Yes |
1817 | 1581 | 1581.0 | 44.02 | 44.0 | Dithiothreitol, A New Protective Reagent For Sh Groups. | W W Cleland | Biochemistry | 1964 | 14192894 | Yes |
1818 | 1580 | 1580.0 | 52.58 | 52.6 | Which elements are excited in electrical stimulation of mammalian central nervous system: a review. | J B Ranck | Brain Res | 1975 | 1102064 | No |
1819 | 1580 | 1580.0 | 48.63 | 48.6 | The role of the amygdala in fear and anxiety. | M Davis | Annu Rev Neurosci | 1992 | 1575447 | No |
1820 | 1580 | 1580.0 | 35.63 | 35.6 | The genetical evolution of social behaviour. II. | W D Hamilton | J Theor Biol | 1964 | 5875340 | Yes |
1821 | 1580 | 1580.0 | 47.49 | 47.5 | Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance. | L Bravo | Nutr Rev | 1998 | 9838798 | No |
1822 | 1580 | 1580.0 | 31.23 | 31.2 | Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy. | R K Jain | Nat Med | 2001 | 11533692 | No |
1823 | 3159 | 1579.5 | 62.48 | 31.2 | NF-kappaB regulation in the immune system. | Qiutang Li, Inder M Verma | Nat Rev Immunol | 2002 | 12360211 | No |
1824 | 3157 | 1578.5 | 70.4 | 35.2 | Lipopolysaccharide endotoxins. | Christian R H Raetz, Chris Whitfield | Annu Rev Biochem | 2002 | 12045108 | No |
1825 | 1578 | 1578.0 | 37.36 | 37.4 | The blood-brain barrier: bottleneck in brain drug development. | William M Pardridge | NeuroRx | 2005 | 15717053 | No |
1826 | 1577 | 1577.0 | 34.06 | 34.1 | Mechanisms of bone metastasis. | G David Roodman | N Engl J Med | 2004 | 15084698 | No |
1827 | 3154 | 1577.0 | 92.64 | 46.3 | Density functionals with broad applicability in chemistry. | Yan Zhao, Donald G Truhlar | Acc Chem Res | 2008 | 18186612 | Yes |
1828 | 3152 | 1576.0 | 115.79 | 57.9 | A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms. | J A Horne, O Ostberg | Int J Chronobiol | 1976 | 1027738 | Yes |
1829 | 1576 | 1576.0 | 42.64 | 42.6 | The complete general secretory pathway in gram-negative bacteria. | A P Pugsley | Microbiol Rev | 1993 | 8096622 | No |
1830 | 3152 | 1576.0 | 174.35 | 87.2 | Natural Products as Sources of New Drugs from 1981 to 2014. | David J Newman, Gordon M Cragg | J Nat Prod | 2016 | 26852623 | No |
1831 | 4725 | 1575.0 | 128.88 | 43.0 | Dating of the human-ape splitting by a molecular clock of mitochondrial DNA. | M Hasegawa, H Kishino, T Yano | J Mol Evol | 1985 | 3934395 | Yes |
1832 | 1574 | 1574.0 | 52.5 | 52.5 | Biology of interleukin 1. | C A Dinarello | FASEB J | 1988 | 3277884 | No |
1833 | 1574 | 1574.0 | 45.0 | 45.0 | Glycosphingolipids in cellular interaction, differentiation, and oncogenesis. | S Hakomori | Annu Rev Biochem | 1981 | 7023369 | No |
1834 | 3148 | 1574.0 | 68.47 | 34.2 | Neurotrophins: roles in neuronal development and function. | E J Huang, L F Reichardt | Annu Rev Neurosci | 2001 | 11520916 | No |
1835 | 3148 | 1574.0 | 99.82 | 49.9 | Palladium-catalyzed ligand-directed C-H functionalization reactions. | Thomas W Lyons, Melanie S Sanford | Chem Rev | 2010 | 20078038 | No |
1836 | 1573 | 1573.0 | 40.08 | 40.1 | Aspergillus fumigatus and aspergillosis. | J P Latgé | Clin Microbiol Rev | 1999 | 10194462 | No |
1837 | 1573 | 1573.0 | 29.98 | 30.0 | Immunosuppressive networks in the tumour environment and their therapeutic relevance. | Weiping Zou | Nat Rev Cancer | 2005 | 15776005 | No |
1838 | 1573 | 1573.0 | 36.63 | 36.6 | Insulin and insulin-like growth factor signalling in neoplasia. | Michael Pollak | Nat Rev Cancer | 2008 | 19029956 | No |
1839 | 3145 | 1572.5 | 64.75 | 32.4 | Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions. | E Krissinel, K Henrick | Acta Crystallogr D Biol Crystallogr | 2004 | 15572779 | Yes |
1840 | 4717 | 1572.3 | 115.15 | 38.4 | Two-photon laser scanning fluorescence microscopy. | W Denk, J H Strickler, W W Webb | Science | 1990 | 2321027 | Yes |
1841 | 17293 | 1572.1 | 547.29 | 49.8 | A new equation to estimate glomerular filtration rate. | Andrew S Levey, Lesley A Stevens, Christopher H Schmid, Yaping Lucy Zhang, Alejandro F Castro, Harold I Feldman, John W Kusek, Paul Eggers, Frederick Van Lente, Tom Greene, Josef Coresh | Ann Intern Med | 2009 | 19414839 | Yes |
1842 | 3144 | 1572.0 | 98.64 | 49.3 | Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. | G R Gibson, M B Roberfroid | J Nutr | 1995 | 7782892 | No |
1843 | 3144 | 1572.0 | 57.99 | 29.0 | The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. | Michael H Glickman, Aaron Ciechanover | Physiol Rev | 2002 | 11917093 | No |
1844 | 3144 | 1572.0 | 88.13 | 44.1 | Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research. | Sally S Dickerson, Margaret E Kemeny | Psychol Bull | 2004 | 15122924 | Yes |
1845 | 1571 | 1571.0 | 37.79 | 37.8 | HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy. | J M Coffin | Science | 1995 | 7824947 | Yes |
1846 | 1571 | 1571.0 | 30.4 | 30.4 | Regulatory T cells, tumour immunity and immunotherapy. | Weiping Zou | Nat Rev Immunol | 2006 | 16557261 | No |
1847 | 1570 | 1570.0 | 41.53 | 41.5 | Molecular bases of the acute coronary syndromes. | P Libby | Circulation | 1995 | 7758192 | No |
1848 | 3139 | 1569.5 | 61.25 | 30.6 | The evolutionary fate and consequences of duplicate genes. | M Lynch, J S Conery | Science | 2000 | 11073452 | No |
1849 | 1569 | 1569.0 | 59.97 | 60.0 | Local effector functions of capsaicin-sensitive sensory nerve endings: involvement of tachykinins, calcitonin gene-related peptide and other neuropeptides. | P Holzer | Neuroscience | 1988 | 3288903 | No |
1850 | 1569 | 1569.0 | 29.62 | 29.6 | Intrinsically unstructured proteins. | Peter Tompa | Trends Biochem Sci | 2002 | 12368089 | No |
1851 | 3134 | 1567.0 | 60.52 | 30.3 | Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. | O Tetsu, F McCormick | Nature | 1999 | 10201372 | Yes |
1852 | 3134 | 1567.0 | 126.81 | 63.4 | Methods for the thematic synthesis of qualitative research in systematic reviews. | James Thomas, Angela Harden | BMC Med Res Methodol | 2008 | 18616818 | Yes |
1853 | 1567 | 1567.0 | 103.95 | 104.0 | The Global Epidemic of the Metabolic Syndrome. | Mohammad G Saklayen | Curr Hypertens Rep | 2018 | 29480368 | No |
1854 | 3131 | 1565.5 | 96.79 | 48.4 | Oxidative stress and diabetic complications. | Ferdinando Giacco, Michael Brownlee | Circ Res | 2010 | 21030723 | No |
1855 | 1565 | 1565.0 | 0.0 | 0.0 | The estimation of phosphorus. | R J Allen | Biochem J | 1940 | 16747230 | Yes |
1856 | 3129 | 1564.5 | 67.97 | 34.0 | Microtubules as a target for anticancer drugs. | Mary Ann Jordan, Leslie Wilson | Nat Rev Cancer | 2004 | 15057285 | No |
1857 | 1564 | 1564.0 | 106.48 | 106.5 | Anterior acromioplasty for the chronic impingement syndrome in the shoulder: a preliminary report. | C S Neer | J Bone Joint Surg Am | 1972 | 5054450 | Yes |
1858 | 1564 | 1564.0 | 0.0 | 0.0 | A modified spectrophotometric determination of chymotrypsin, trypsin, and thrombin. | B C Hummel | Can J Biochem Physiol | 1959 | 14405350 | Yes |
1859 | 1564 | 1564.0 | 39.02 | 39.0 | Marine viruses--major players in the global ecosystem. | Curtis A Suttle | Nat Rev Microbiol | 2007 | 17853907 | No |
1860 | 1563 | 1563.0 | 28.52 | 28.5 | Selforganization of matter and the evolution of biological macromolecules. | M Eigen | Naturwissenschaften | 1971 | 4942363 | No |
1861 | 1563 | 1563.0 | 66.55 | 66.5 | Structure, Function, and Evolution of Coronavirus Spike Proteins. | Fang Li | Annu Rev Virol | 2016 | 27578435 | No |
1862 | 3125 | 1562.5 | 67.09 | 33.5 | Complex networks orchestrate epithelial-mesenchymal transitions. | Jean Paul Thiery, Jonathan P Sleeman | Nat Rev Mol Cell Biol | 2006 | 16493418 | No |
1863 | 1562 | 1562.0 | 33.37 | 33.4 | From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels. | W A Catterall | Neuron | 2000 | 10798388 | No |
1864 | 1562 | 1562.0 | 29.74 | 29.7 | Protein degradation and protection against misfolded or damaged proteins. | Alfred L Goldberg | Nature | 2003 | 14685250 | No |
1865 | 3123 | 1561.5 | 134.15 | 67.1 | Parkinson's disease. | Lorraine V Kalia, Anthony E Lang | Lancet | 2015 | 25904081 | No |
1866 | 1561 | 1561.0 | 47.61 | 47.6 | Ordinary magic. Resilience processes in development. | A S Masten | Am Psychol | 2001 | 11315249 | Yes |
1867 | 1561 | 1561.0 | 46.31 | 46.3 | A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. | Ozcan Erel | Clin Biochem | 2004 | 15003729 | Yes |
1868 | 1561 | 1561.0 | 35.71 | 35.7 | Neurotrophin-regulated signalling pathways. | Louis F Reichardt | Philos Trans R Soc Lond B Biol Sci | 2006 | 16939974 | No |
1869 | 1560 | 1560.0 | 37.23 | 37.2 | The biology of incretin hormones. | Daniel J Drucker | Cell Metab | 2006 | 16517403 | No |
1870 | 1559 | 1559.0 | 52.45 | 52.5 | Screening for prostate cancer: U.S. Preventive Services Task Force recommendation statement. | Virginia A Moyer | Ann Intern Med | 2012 | 22801674 | No |
1871 | 4676 | 1558.7 | 120.9 | 40.3 | Optimization by simulated annealing. | S Kirkpatrick, C D Gelatt, M P Vecchi | Science | 1983 | 17813860 | Yes |
1872 | 3116 | 1558.0 | 65.39 | 32.7 | Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome. | C B Lozzio, B B Lozzio | Blood | 1975 | 163658 | Yes |
1873 | 3115 | 1557.5 | 100.98 | 50.5 | The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today. | R Doll, R Peto | J Natl Cancer Inst | 1981 | 7017215 | No |
1874 | 4672 | 1557.3 | 87.16 | 29.1 | Notch signaling: cell fate control and signal integration in development. | S Artavanis-Tsakonas, M D Rand, R J Lake | Science | 1999 | 10221902 | No |
1875 | 3113 | 1556.5 | 74.28 | 37.1 | Unravelling the pathogenesis of inflammatory bowel disease. | R J Xavier, D K Podolsky | Nature | 2007 | 17653185 | No |
1876 | 1556 | 1556.0 | 31.39 | 31.4 | The ubiquitin-proteasome proteolytic pathway. | A Ciechanover | Cell | 1994 | 7923371 | No |
1877 | 1556 | 1556.0 | 25.87 | 25.9 | Neuronal specification in the spinal cord: inductive signals and transcriptional codes. | T M Jessell | Nat Rev Genet | 2000 | 11262869 | No |
1878 | 3112 | 1556.0 | 69.95 | 35.0 | The human plasma proteome: history, character, and diagnostic prospects. | N Leigh Anderson, Norman G Anderson | Mol Cell Proteomics | 2002 | 12488461 | No |
1879 | 3110 | 1555.0 | 66.83 | 33.4 | Cancer metastasis: building a framework. | Gaorav P Gupta, Joan Massagué | Cell | 2006 | 17110329 | No |
1880 | 1555 | 1555.0 | 52.09 | 52.1 | The role of senescent cells in ageing. | Jan M van Deursen | Nature | 2014 | 24848057 | No |
1881 | 4664 | 1554.7 | 92.26 | 30.8 | Efficient selection for high-expression transfectants with a novel eukaryotic vector. | H Niwa, K Yamamura, J Miyazaki | Gene | 1991 | 1660837 | Yes |
1882 | 4664 | 1554.7 | 103.8 | 34.6 | Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer. | M A Frohman, M K Dush, G R Martin | Proc Natl Acad Sci U S A | 1988 | 2461560 | Yes |
1883 | 1554 | 1554.0 | 77.47 | 77.5 | Bias in analytic research. | D L Sackett | J Chronic Dis | 1979 | 447779 | Yes |
1884 | 3108 | 1554.0 | 123.4 | 61.7 | Alginate: properties and biomedical applications. | Kuen Yong Lee, David J Mooney | Prog Polym Sci | 2012 | 22125349 | Yes |
1885 | 1554 | 1554.0 | 58.74 | 58.7 | Modeling Development and Disease with Organoids. | Hans Clevers | Cell | 2016 | 27315476 | No |
1886 | 3106 | 1553.0 | 43.43 | 21.7 | Computed circular dichroism spectra for the evaluation of protein conformation. | N Greenfield, G D Fasman | Biochemistry | 1969 | 5346390 | Yes |
1887 | 6208 | 1552.0 | 153.45 | 38.4 | Most mammalian mRNAs are conserved targets of microRNAs. | Robin C Friedman, Kyle Kai-How Farh, Christopher B Burge, David P Bartel | Genome Res | 2009 | 18955434 | Yes |
1888 | 3104 | 1552.0 | 79.5 | 39.8 | Dali server: conservation mapping in 3D. | Liisa Holm, Päivi Rosenström | Nucleic Acids Res | 2010 | 20457744 | Yes |
1889 | 3103 | 1551.5 | 58.35 | 29.2 | Mutations affecting segment number and polarity in Drosophila. | C Nüsslein-Volhard, E Wieschaus | Nature | 1980 | 6776413 | Yes |
1890 | 1551 | 1551.0 | 77.61 | 77.6 | Muscle and tendon: properties, models, scaling, and application to biomechanics and motor control. | F E Zajac | Crit Rev Biomed Eng | 1989 | 2676342 | No |
1891 | 1551 | 1551.0 | 32.48 | 32.5 | Drug discovery: a historical perspective. | J Drews | Science | 2000 | 10720314 | No |
1892 | 1551 | 1551.0 | 33.32 | 33.3 | Tumor metastasis: mechanistic insights and clinical challenges. | Patricia S Steeg | Nat Med | 2006 | 16892035 | No |
1893 | 3101 | 1550.5 | 100.32 | 50.2 | Neoantigens in cancer immunotherapy. | Ton N Schumacher, Robert D Schreiber | Science | 2015 | 25838375 | No |
1894 | 1550 | 1550.0 | 41.07 | 41.1 | A more meaningful scoring system for determining the severity of coronary heart disease. | G G Gensini | Am J Cardiol | 1983 | 6823874 | Yes |
1895 | 4648 | 1549.3 | 88.46 | 29.5 | A highly sensitive adenylate cyclase assay. | Y Salomon, C Londos, M Rodbell | Anal Biochem | 1974 | 4827395 | Yes |
1896 | 1549 | 1549.0 | 36.56 | 36.6 | The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. | H Maeda | Adv Enzyme Regul | 2001 | 11384745 | No |
1897 | 3098 | 1549.0 | 66.4 | 33.2 | Self-assembly at all scales. | George M Whitesides, Bartosz Grzybowski | Science | 2002 | 11923529 | Yes |
1898 | 1547 | 1547.0 | 42.39 | 42.4 | Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum. | A Fabiato | Am J Physiol | 1983 | 6346892 | No |
1899 | 3094 | 1547.0 | 73.75 | 36.9 | Malignant gliomas in adults. | Patrick Y Wen, Santosh Kesari | N Engl J Med | 2008 | 18669428 | No |
1900 | 3093 | 1546.5 | 102.79 | 51.4 | The future of immune checkpoint therapy. | Padmanee Sharma, James P Allison | Science | 2015 | 25838373 | No |
1901 | 15462 | 1546.2 | 368.77 | 36.9 | Multilineage potential of adult human mesenchymal stem cells. | M F Pittenger, A M Mackay, S C Beck, R K Jaiswal, R Douglas, J D Mosca, M A Moorman, D W Simonetti, S Craig, D R Marshak | Science | 1999 | 10102814 | Yes |
1902 | 1546 | 1546.0 | 73.4 | 73.4 | Computing Inter-Rater Reliability for Observational Data: An Overview and Tutorial. | Kevin A Hallgren | Tutor Quant Methods Psychol | 2012 | 22833776 | Yes |
1903 | 4636 | 1545.3 | 155.35 | 51.8 | Phylogenetic identification and in situ detection of individual microbial cells without cultivation. | R I Amann, W Ludwig, K H Schleifer | Microbiol Rev | 1995 | 7535888 | No |
1904 | 3090 | 1545.0 | 62.01 | 31.0 | Toll-like receptor control of the adaptive immune responses. | Akiko Iwasaki, Ruslan Medzhitov | Nat Immunol | 2004 | 15454922 | No |
1905 | 1544 | 1544.0 | 47.22 | 47.2 | Domino Reactions in Organic Synthesis. | Lutz F. Tietze | Chem Rev | 1996 | 11848746 | Yes |
1906 | 9260 | 1543.3 | 219.35 | 36.6 | GROMACS: fast, flexible, and free. | David Van Der Spoel, Erik Lindahl, Berk Hess, Gerrit Groenhof, Alan E Mark, Herman J C Berendsen | J Comput Chem | 2005 | 16211538 | Yes |
1907 | 1542 | 1542.0 | 30.36 | 30.4 | E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. | J R Nevins | Science | 1992 | 1411535 | Yes |
1908 | 1542 | 1542.0 | 44.04 | 44.0 | Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy. | A E Pegg | Cancer Res | 1988 | 3123052 | No |
1909 | 1542 | 1542.0 | 0.0 | 0.0 | Cerebral vascular accidents in patients over the age of 60. II. Prognosis. | J Rankin | Scott Med J | 1957 | 13432835 | Yes |
1910 | 3083 | 1541.5 | 74.69 | 37.3 | Steatohepatitis: a tale of two "hits"? | C P Day, O F James | Gastroenterology | 1998 | 9547102 | No |
1911 | 3083 | 1541.5 | 74.94 | 37.5 | Cell signaling by receptor tyrosine kinases. | Mark A Lemmon, Joseph Schlessinger | Cell | 2010 | 20602996 | No |
1912 | 3082 | 1541.0 | 71.8 | 35.9 | New Giemsa method for the differential staining of sister chromatids. | P Perry, S Wolff | Nature | 1974 | 4138930 | Yes |
1913 | 1541 | 1541.0 | 53.74 | 53.7 | Multimodal approach to control postoperative pathophysiology and rehabilitation. | H Kehlet | Br J Anaesth | 1997 | 9175983 | No |
1914 | 1540 | 1540.0 | 56.13 | 56.1 | Statistical analysis of enzyme kinetic data. | W W Cleland | Methods Enzymol | 1979 | 502857 | Yes |
1915 | 1540 | 1540.0 | 34.92 | 34.9 | Pathogenesis of group A streptococcal infections. | M W Cunningham | Clin Microbiol Rev | 2000 | 10885988 | No |
1916 | 1540 | 1540.0 | 43.56 | 43.6 | Glycobiology: Toward Understanding the Function of Sugars. | Raymond A. Dwek | Chem Rev | 1996 | 11848770 | Yes |
1917 | 1540 | 1540.0 | 65.55 | 65.5 | Macrophage Polarization. | Peter J Murray | Annu Rev Physiol | 2017 | 27813830 | No |
1918 | 1539 | 1539.0 | 30.95 | 30.9 | RNA silencing in plants. | David Baulcombe | Nature | 2004 | 15372043 | No |
1919 | 1538 | 1538.0 | 52.92 | 52.9 | Biological applications of ionophores. | B C Pressman | Annu Rev Biochem | 1976 | 786156 | No |
1920 | 1538 | 1538.0 | 34.0 | 34.0 | Molecular themes in oncogenesis. | J M Bishop | Cell | 1991 | 1988146 | No |
1921 | 1538 | 1538.0 | 47.8 | 47.8 | Evidence for a central component of post-injury pain hypersensitivity. | C J Woolf | Nature | 1983 | 6656869 | Yes |
1922 | 1537 | 1537.0 | 42.64 | 42.6 | Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy. | Y Ben-Ari | Neuroscience | 1985 | 2859548 | No |
1923 | 3074 | 1537.0 | 78.98 | 39.5 | Empirical threshold values for quantitative trait mapping. | G A Churchill, R W Doerge | Genetics | 1994 | 7851788 | Yes |
1924 | 3073 | 1536.5 | 0.0 | 0.0 | A method for the determination of desoxyribonucleic acid, ribonucleic acid, and phosphoproteins in animal tissues. | G Schmidt, S J Thannhauser | J Biol Chem | 1945 | 21005717 | Yes |
1925 | 1536 | 1536.0 | 30.77 | 30.8 | The Buccaneer software for automated model building. 1. Tracing protein chains. | Kevin Cowtan | Acta Crystallogr D Biol Crystallogr | 2006 | 16929101 | Yes |
1926 | 1535 | 1535.0 | 45.82 | 45.8 | Calcium release from the sarcoplasmic reticulum. | M Endo | Physiol Rev | 1977 | 13441 | Yes |
1927 | 1535 | 1535.0 | 60.9 | 60.9 | A structured interview guide for the Hamilton Depression Rating Scale. | J B Williams | Arch Gen Psychiatry | 1988 | 3395203 | Yes |
1928 | 1535 | 1535.0 | 0.0 | 0.0 | Nutrition needs of mammalian cells in tissue culture. | H Eagle | Science | 1955 | 13255879 | Yes |
1929 | 3070 | 1535.0 | 15.51 | 7.8 | Junctional complexes in various epithelia. | M G Farquhar, G E Palade | J Cell Biol | 1963 | 13944428 | Yes |
1930 | 1535 | 1535.0 | 31.29 | 31.3 | Antigen-Antibody Crossed Electrophoresis. | C B Laurell | Anal Biochem | 1965 | 14302464 | Yes |
1931 | 3069 | 1534.5 | 105.45 | 52.7 | Diabetes and cardiovascular disease. The Framingham study. | W B Kannel, D L McGee | JAMA | 1979 | 430798 | Yes |
1932 | 1534 | 1534.0 | 24.04 | 24.0 | An enzymic method for the trace iodination of immunoglobulins and other proteins. | J J Marchalonis | Biochem J | 1969 | 4185494 | Yes |
1933 | 1534 | 1534.0 | 48.14 | 48.1 | The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate. | G R Buettner | Arch Biochem Biophys | 1993 | 8434935 | No |
1934 | 1534 | 1534.0 | 35.95 | 36.0 | Upconversion and anti-Stokes processes with f and d ions in solids. | François Auzel | Chem Rev | 2004 | 14719973 | Yes |
1935 | 1534 | 1534.0 | 41.96 | 42.0 | n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases. | Philip C Calder | Am J Clin Nutr | 2006 | 16841861 | No |
1936 | 1534 | 1534.0 | 38.02 | 38.0 | Use and misuse of the receiver operating characteristic curve in risk prediction. | Nancy R Cook | Circulation | 2007 | 17309939 | Yes |
1937 | 3067 | 1533.5 | 114.2 | 57.1 | Universal chemical assay for the detection and determination of siderophores. | B Schwyn, J B Neilands | Anal Biochem | 1987 | 2952030 | Yes |
1938 | 3066 | 1533.0 | 67.6 | 33.8 | Cell migration: a physically integrated molecular process. | D A Lauffenburger, A F Horwitz | Cell | 1996 | 8608589 | No |
1939 | 1533 | 1533.0 | 61.46 | 61.5 | α-band oscillations, attention, and controlled access to stored information. | Wolfgang Klimesch | Trends Cogn Sci | 2012 | 23141428 | No |
1940 | 1533 | 1533.0 | 58.51 | 58.5 | A Protection Motivation Theory of Fear Appeals and Attitude Change1. | Ronald W Rogers | J Psychol | 1975 | 28136248 | Yes |
1941 | 3064 | 1532.0 | 70.85 | 35.4 | A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. | L Buck, R Axel | Cell | 1991 | 1840504 | Yes |
1942 | 1532 | 1532.0 | 38.72 | 38.7 | Early signals in the mitogenic response. | E Rozengurt | Science | 1986 | 3018928 | No |
1943 | 1532 | 1532.0 | 36.88 | 36.9 | Myeloperoxidase: friend and foe. | Seymour J Klebanoff | J Leukoc Biol | 2005 | 15689384 | No |
1944 | 1532 | 1532.0 | 43.43 | 43.4 | Surface plasmon resonance sensors for detection of chemical and biological species. | Jirí Homola | Chem Rev | 2008 | 18229953 | No |
1945 | 1531 | 1531.0 | 45.37 | 45.4 | Recent advances in the biochemistry of polyamines in eukaryotes. | A E Pegg | Biochem J | 1986 | 3087344 | No |
1946 | 3062 | 1531.0 | 61.78 | 30.9 | The Bcl2 family: regulators of the cellular life-or-death switch. | Suzanne Cory, Jerry M Adams | Nat Rev Cancer | 2002 | 12209154 | No |
1947 | 7655 | 1531.0 | 152.29 | 30.5 | Prospective identification of tumorigenic breast cancer cells. | Muhammad Al-Hajj, Max S Wicha, Adalberto Benito-Hernandez, Sean J Morrison, Michael F Clarke | Proc Natl Acad Sci U S A | 2003 | 12629218 | Yes |
1948 | 6121 | 1530.2 | 119.94 | 30.0 | A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. | B M Bolstad, R A Irizarry, M Astrand, T P Speed | Bioinformatics | 2003 | 12538238 | Yes |
1949 | 1530 | 1530.0 | 48.73 | 48.7 | Some observations upon a new inhibitor of monoamine oxidase in brain tissue. | J P Johnston | Biochem Pharmacol | 1968 | 5659776 | Yes |
1950 | 3060 | 1530.0 | 56.46 | 28.2 | Cellular motility driven by assembly and disassembly of actin filaments. | Thomas D Pollard, Gary G Borisy | Cell | 2003 | 12600310 | No |
1951 | 3058 | 1529.0 | 62.58 | 31.3 | Development by self-digestion: molecular mechanisms and biological functions of autophagy. | Beth Levine, Daniel J Klionsky | Dev Cell | 2004 | 15068787 | No |
1952 | 6112 | 1528.0 | 208.28 | 52.1 | Guidelines for the process of cross-cultural adaptation of self-report measures. | D E Beaton, C Bombardier, F Guillemin, M B Ferraz | Spine (Phila Pa 1976) | 2000 | 11124735 | No |
1953 | 1527 | 1527.0 | 50.69 | 50.7 | Deliberate practice and the acquisition and maintenance of expert performance in medicine and related domains. | K Anders Ericsson | Acad Med | 2004 | 15383395 | No |
1954 | 3053 | 1526.5 | 63.1 | 31.6 | Coordination of circadian timing in mammals. | Steven M Reppert, David R Weaver | Nature | 2002 | 12198538 | No |
1955 | 4578 | 1526.0 | 96.89 | 32.3 | Adjusting batch effects in microarray expression data using empirical Bayes methods. | W Evan Johnson, Cheng Li, Ariel Rabinovic | Biostatistics | 2007 | 16632515 | Yes |
1956 | 3050 | 1525.0 | 180.64 | 90.3 | A scaled version of the General Health Questionnaire. | D P Goldberg, V F Hillier | Psychol Med | 1979 | 424481 | Yes |
1957 | 1525 | 1525.0 | 36.91 | 36.9 | Clinical features of metastatic bone disease and risk of skeletal morbidity. | Robert E Coleman | Clin Cancer Res | 2006 | 17062708 | No |
1958 | 1525 | 1525.0 | 41.3 | 41.3 | Stress and depression. | Constance Hammen | Annu Rev Clin Psychol | 2005 | 17716090 | No |
1959 | 3050 | 1525.0 | 95.04 | 47.5 | How good are my data and what is the resolution? | Philip R Evans, Garib N Murshudov | Acta Crystallogr D Biol Crystallogr | 2013 | 23793146 | Yes |
1960 | 1524 | 1524.0 | 41.31 | 41.3 | Tumor invasion and metastases--role of the extracellular matrix: Rhoads Memorial Award lecture. | L A Liotta | Cancer Res | 1986 | 2998604 | No |
1961 | 1524 | 1524.0 | 34.45 | 34.5 | Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study). | K M Fox | Lancet | 2003 | 13678872 | Yes |
1962 | 1524 | 1524.0 | 63.27 | 63.3 | Nonalcoholic fatty liver disease: a systematic review. | Mary E Rinella | JAMA | 2015 | 26057287 | No |
1963 | 1523 | 1523.0 | 38.08 | 38.1 | Trophic factors and neuronal survival. | Y A Barde | Neuron | 1989 | 2697237 | No |
1964 | 1523 | 1523.0 | 29.77 | 29.8 | Macromolecular crowding: obvious but underappreciated. | R J Ellis | Trends Biochem Sci | 2001 | 11590012 | No |
1965 | 1523 | 1523.0 | 33.8 | 33.8 | Ordered porous materials for emerging applications. | Mark E Davis | Nature | 2002 | 12075343 | No |
1966 | 1523 | 1523.0 | 28.38 | 28.4 | Vienna RNA secondary structure server. | Ivo L Hofacker | Nucleic Acids Res | 2003 | 12824340 | Yes |
1967 | 3045 | 1522.5 | 102.05 | 51.0 | Thermodynamics of protein association reactions: forces contributing to stability. | P D Ross, S Subramanian | Biochemistry | 1981 | 7248271 | Yes |
1968 | 3044 | 1522.0 | 91.41 | 45.7 | Quality control and preprocessing of metagenomic datasets. | Robert Schmieder, Robert Edwards | Bioinformatics | 2011 | 21278185 | Yes |
1969 | 4563 | 1521.0 | 96.82 | 32.3 | The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. | S K Hanks, A M Quinn, T Hunter | Science | 1988 | 3291115 | No |
1970 | 1520 | 1520.0 | 37.91 | 37.9 | Type I diabetes mellitus. A chronic autoimmune disease. | G S Eisenbarth | N Engl J Med | 1986 | 3517648 | No |
1971 | 1520 | 1520.0 | 18.59 | 18.6 | A soluble protein characteristic of the nervous system. | B W Moore | Biochem Biophys Res Commun | 1965 | 4953930 | Yes |
1972 | 3040 | 1520.0 | 75.82 | 37.9 | Obesity. | David W Haslam, W Philip T James | Lancet | 2005 | 16198769 | No |
1973 | 3038 | 1519.0 | 70.92 | 35.5 | Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. | F Q Schafer, G R Buettner | Free Radic Biol Med | 2001 | 11368918 | No |
1974 | 1519 | 1519.0 | 34.31 | 34.3 | The Unified Medical Language System (UMLS): integrating biomedical terminology. | Olivier Bodenreider | Nucleic Acids Res | 2004 | 14681409 | Yes |
1975 | 1518 | 1518.0 | 48.02 | 48.0 | Stability of proteins: small globular proteins. | P L Privalov | Adv Protein Chem | 1979 | 44431 | No |
1976 | 1517 | 1517.0 | 41.91 | 41.9 | Bioactive microbial metabolites. | János Bérdy | J Antibiot (Tokyo) | 2005 | 15813176 | No |
1977 | 1516 | 1516.0 | 34.42 | 34.4 | Dopamine (3-hydroxytyramine) and brain function. | O Hornykiewicz | Pharmacol Rev | 1966 | 5328389 | No |
1978 | 3032 | 1516.0 | 67.07 | 33.5 | NF-kappaB: a key role in inflammatory diseases. | P P Tak, G S Firestein | J Clin Invest | 2001 | 11134171 | No |
1979 | 4548 | 1516.0 | 102.3 | 34.1 | Click Chemistry: Diverse Chemical Function from a Few Good Reactions. | Hartmuth C. Kolb, M G Finn, K. Barry Sharpless | Angew Chem Int Ed Engl | 2001 | 11433435 | Yes |
1980 | 1513 | 1513.0 | 47.98 | 48.0 | Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. | C A Barnes | J Comp Physiol Psychol | 1979 | 221551 | Yes |
1981 | 1513 | 1513.0 | 47.17 | 47.2 | The law of attrition. | Gunther Eysenbach | J Med Internet Res | 2005 | 15829473 | Yes |
1982 | 4537 | 1512.3 | 98.4 | 32.8 | Osteoclast differentiation and activation. | William J Boyle, W Scott Simonet, David L Lacey | Nature | 2003 | 12748652 | No |
1983 | 1512 | 1512.0 | 40.0 | 40.0 | Reversible binding of Pi by beef heart mitochondrial adenosine triphosphatase. | H S Penefsky | J Biol Chem | 1977 | 16006 | Yes |
1984 | 1512 | 1512.0 | 89.42 | 89.4 | Stimulated acoustic emissions from within the human auditory system. | D T Kemp | J Acoust Soc Am | 1978 | 744838 | Yes |
1985 | 1512 | 1512.0 | 50.61 | 50.6 | A Social Neuroscience Perspective on Adolescent Risk-Taking. | Laurence Steinberg | Dev Rev | 2008 | 18509515 | Yes |
1986 | 3024 | 1512.0 | 140.87 | 70.4 | MicroRNA therapeutics: towards a new era for the management of cancer and other diseases. | Rajesha Rupaimoole, Frank J Slack | Nat Rev Drug Discov | 2017 | 28209991 | No |
1987 | 9067 | 1511.2 | 260.14 | 43.4 | A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. | Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier | Science | 2012 | 22745249 | Yes |
1988 | 1511 | 1511.0 | 55.73 | 55.7 | Atherogenesis: a postprandial phenomenon. | D B Zilversmit | Circulation | 1979 | 222498 | Yes |
1989 | 1511 | 1511.0 | 28.04 | 28.0 | Aggresomes, inclusion bodies and protein aggregation. | R R Kopito | Trends Cell Biol | 2000 | 11121744 | No |
1990 | 3022 | 1511.0 | 80.11 | 40.1 | The gut microbiota shapes intestinal immune responses during health and disease. | June L Round, Sarkis K Mazmanian | Nat Rev Immunol | 2009 | 19343057 | No |
1991 | 3022 | 1511.0 | 104.79 | 52.4 | Van der Waals heterostructures. | A K Geim, I V Grigorieva | Nature | 2013 | 23887427 | Yes |
1992 | 4528 | 1509.3 | 162.19 | 54.1 | Hydroperoxide metabolism in mammalian organs. | B Chance, H Sies, A Boveris | Physiol Rev | 1979 | 37532 | Yes |
1993 | 1509 | 1509.0 | 50.1 | 50.1 | Stereology of arbitrary particles. A review of unbiased number and size estimators and the presentation of some new ones, in memory of William R. Thompson. | H J Gundersen | J Microsc | 1986 | 3761363 | Yes |
1994 | 1508 | 1508.0 | 33.07 | 33.1 | Far-field optical nanoscopy. | Stefan W Hell | Science | 2007 | 17525330 | No |
1995 | 1508 | 1508.0 | 32.78 | 32.8 | The tumor microenvironment and its role in promoting tumor growth. | T L Whiteside | Oncogene | 2008 | 18836471 | No |
1996 | 4522 | 1507.3 | 115.38 | 38.5 | Cortical surface-based analysis. II: Inflation, flattening, and a surface-based coordinate system. | B Fischl, M I Sereno, A M Dale | Neuroimage | 1999 | 9931269 | Yes |
1997 | 1507 | 1507.0 | 45.17 | 45.2 | Signal transduction by reactive oxygen species. | Toren Finkel | J Cell Biol | 2011 | 21746850 | No |
1998 | 3012 | 1506.0 | 58.98 | 29.5 | Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. | P J Mitchell, R Tjian | Science | 1989 | 2667136 | No |
1999 | 3010 | 1505.0 | 107.91 | 54.0 | The M1 and M2 paradigm of macrophage activation: time for reassessment. | Fernando O Martinez, Siamon Gordon | F1000Prime Rep | 2014 | 24669294 | No |
2000 | 3007 | 1503.5 | 79.54 | 39.8 | Materials for electrochemical capacitors. | Patrice Simon, Yury Gogotsi | Nat Mater | 2008 | 18956000 | Yes |
2001 | 3006 | 1503.0 | 86.23 | 43.1 | What's the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes. | J Zhang, K F Yu | JAMA | 1998 | 9832001 | Yes |
2002 | 3006 | 1503.0 | 57.44 | 28.7 | Missing pieces in the NF-kappaB puzzle. | Sankar Ghosh, Michael Karin | Cell | 2002 | 11983155 | No |
2003 | 1503 | 1503.0 | 33.63 | 33.6 | The molecular logic of endocannabinoid signalling. | Daniele Piomelli | Nat Rev Neurosci | 2003 | 14595399 | No |
2004 | 1502 | 1502.0 | 51.56 | 51.6 | Lyme disease. | A C Steere | N Engl J Med | 1989 | 2668764 | No |
2005 | 1502 | 1502.0 | 47.91 | 47.9 | Health consequences of obesity in youth: childhood predictors of adult disease. | W H Dietz | Pediatrics | 1998 | 12224658 | No |
2006 | 1502 | 1502.0 | 59.01 | 59.0 | Screening for lung cancer: U.S. Preventive Services Task Force recommendation statement. | Virginia A Moyer | Ann Intern Med | 2014 | 24378917 | No |
2007 | 3003 | 1501.5 | 86.78 | 43.4 | Accessories to the crime: functions of cells recruited to the tumor microenvironment. | Douglas Hanahan, Lisa M Coussens | Cancer Cell | 2012 | 22439926 | No |
2008 | 1501 | 1501.0 | 34.16 | 34.2 | Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors. | J C Unkeless | J Exp Med | 1979 | 90108 | Yes |
2009 | 3002 | 1501.0 | 67.73 | 33.9 | The DNA damage response: making it safe to play with knives. | Alberto Ciccia, Stephen J Elledge | Mol Cell | 2010 | 20965415 | No |
2010 | 3001 | 1500.5 | 89.77 | 44.9 | Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI. | P J Basser, C Pierpaoli | J Magn Reson B | 1996 | 8661285 | Yes |
2011 | 1500 | 1500.0 | 40.33 | 40.3 | Rheumatoid arthritis. Pathophysiology and implications for therapy. | E D Harris | N Engl J Med | 1990 | 2271017 | No |
2012 | 1500 | 1500.0 | 31.61 | 31.6 | Cancer epigenomics: DNA methylomes and histone-modification maps. | Manel Esteller | Nat Rev Genet | 2007 | 17339880 | No |
2013 | 2999 | 1499.5 | 88.97 | 44.5 | Extended-connectivity fingerprints. | David Rogers, Mathew Hahn | J Chem Inf Model | 2010 | 20426451 | Yes |
2014 | 4498 | 1499.3 | 126.9 | 42.3 | The fusiform face area: a module in human extrastriate cortex specialized for face perception. | N Kanwisher, J McDermott, M M Chun | J Neurosci | 1997 | 9151747 | Yes |
2015 | 2998 | 1499.0 | 78.75 | 39.4 | Lipid rafts as a membrane-organizing principle. | Daniel Lingwood, Kai Simons | Science | 2010 | 20044567 | No |
2016 | 1498 | 1498.0 | 42.74 | 42.7 | Isolated removal of hypothalamic or other brain nuclei of the rat. | M Palkovits | Brain Res | 1973 | 4747772 | Yes |
2017 | 1497 | 1497.0 | 33.68 | 33.7 | Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone. | M B Luskin | Neuron | 1993 | 8338665 | Yes |
2018 | 8981 | 1496.8 | 282.8 | 47.1 | TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. | Daehwan Kim, Geo Pertea, Cole Trapnell, Harold Pimentel, Ryan Kelley, Steven L Salzberg | Genome Biol | 2013 | 23618408 | Yes |
2019 | 2993 | 1496.5 | 0.0 | 0.0 | Lactic dehydrogenase activity in blood. | F Wroblewski, J S Ladue | Proc Soc Exp Biol Med | 1955 | 13273400 | Yes |
2020 | 2992 | 1496.0 | 176.21 | 88.1 | Rating systems in the evaluation of knee ligament injuries. | Y Tegner, J Lysholm | Clin Orthop Relat Res | 1985 | 4028566 | Yes |
2021 | 1496 | 1496.0 | 32.99 | 33.0 | Hyaluronan: from extracellular glue to pericellular cue. | Bryan P Toole | Nat Rev Cancer | 2004 | 15229478 | No |
2022 | 1495 | 1495.0 | 0.0 | 0.0 | The colorimetric determination of phosphorus. | E J King | Biochem J | 1932 | 16744823 | Yes |
2023 | 1494 | 1494.0 | 39.06 | 39.1 | The human immunodeficiency virus: infectivity and mechanisms of pathogenesis. | A S Fauci | Science | 1988 | 3277274 | No |
2024 | 2988 | 1494.0 | 88.39 | 44.2 | Porosity of 3D biomaterial scaffolds and osteogenesis. | Vassilis Karageorgiou, David Kaplan | Biomaterials | 2005 | 15860204 | No |
2025 | 1493 | 1493.0 | 33.13 | 33.1 | Tumor suppressor genes. | R A Weinberg | Science | 1991 | 1659741 | No |
2026 | 2986 | 1493.0 | 60.3 | 30.1 | Chemokines: a new classification system and their role in immunity. | A Zlotnik, O Yoshie | Immunity | 2000 | 10714678 | No |
2027 | 1492 | 1492.0 | 37.11 | 37.1 | Reconciling the chemistry and biology of reactive oxygen species. | Christine C Winterbourn | Nat Chem Biol | 2008 | 18421291 | No |
2028 | 2983 | 1491.5 | 0.0 | 0.0 | Mutations of Bacteria from Virus Sensitivity to Virus Resistance. | S E Luria, M Delbrück | Genetics | 1943 | 17247100 | Yes |
2029 | 1491 | 1491.0 | 29.72 | 29.7 | Coupling of enzymes to proteins with glutaraldehyde. Use of the conjugates for the detection of antigens and antibodies. | S Avrameas | Immunochemistry | 1969 | 4975324 | Yes |
2030 | 4473 | 1491.0 | 120.79 | 40.3 | I-TASSER: a unified platform for automated protein structure and function prediction. | Ambrish Roy, Alper Kucukural, Yang Zhang | Nat Protoc | 2010 | 20360767 | Yes |
2031 | 1489 | 1489.0 | 33.16 | 33.2 | Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis. | C Taswell | J Immunol | 1981 | 7009746 | Yes |
2032 | 1489 | 1489.0 | 39.82 | 39.8 | Redox signaling: nitrosylation and related target interactions of nitric oxide. | J S Stamler | Cell | 1994 | 7923362 | No |
2033 | 2978 | 1489.0 | 65.97 | 33.0 | How matrix metalloproteinases regulate cell behavior. | M D Sternlicht, Z Werb | Annu Rev Cell Dev Biol | 2001 | 11687497 | No |
2034 | 1488 | 1488.0 | 58.43 | 58.4 | MorphoJ: an integrated software package for geometric morphometrics. | Christian Peter Klingenberg | Mol Ecol Resour | 2011 | 21429143 | Yes |
2035 | 1487 | 1487.0 | 36.91 | 36.9 | An economic method for the fluorescent labeling of PCR fragments. | M Schuelke | Nat Biotechnol | 2000 | 10657137 | Yes |
2036 | 2974 | 1487.0 | 91.79 | 45.9 | LigPlot+: multiple ligand-protein interaction diagrams for drug discovery. | Roman A Laskowski, Mark B Swindells | J Chem Inf Model | 2011 | 21919503 | Yes |
2037 | 1486 | 1486.0 | 19.99 | 20.0 | The mechanism of muscular contraction. | H E Huxley | Science | 1969 | 4181952 | No |
2038 | 1486 | 1486.0 | 21.52 | 21.5 | Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate. | J W Olney | Science | 1969 | 5778021 | Yes |
2039 | 1486 | 1486.0 | 46.19 | 46.2 | Polycystic ovary syndrome. | S Franks | N Engl J Med | 1995 | 7651477 | No |
2040 | 1486 | 1486.0 | 26.0 | 26.0 | Histone acetylation and transcriptional regulatory mechanisms. | K Struhl | Genes Dev | 1998 | 9499396 | No |
2041 | 1485 | 1485.0 | 41.15 | 41.1 | Emotion regulation: affective, cognitive, and social consequences. | James J Gross | Psychophysiology | 2002 | 12212647 | No |
2042 | 1485 | 1485.0 | 48.51 | 48.5 | The World Oral Health Report 2003: continuous improvement of oral health in the 21st century--the approach of the WHO Global Oral Health Programme. | Poul Erik Petersen | Community Dent Oral Epidemiol | 2003 | 15015736 | Yes |
2043 | 1485 | 1485.0 | 32.01 | 32.0 | Critical period plasticity in local cortical circuits. | Takao K Hensch | Nat Rev Neurosci | 2005 | 16261181 | No |
2044 | 1484 | 1484.0 | 42.98 | 43.0 | Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. | M D Maines | FASEB J | 1988 | 3290025 | No |
2045 | 1484 | 1484.0 | 49.82 | 49.8 | The measurement of psychological androgyny. | S L Bem | J Consult Clin Psychol | 1974 | 4823550 | Yes |
2046 | 1484 | 1484.0 | 40.69 | 40.7 | Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms. | J A Beavo | Physiol Rev | 1995 | 7480160 | No |
2047 | 1484 | 1484.0 | 47.84 | 47.8 | SPSS and SAS programs for determining the number of components using parallel analysis and velicer's MAP test. | B P O'Connor | Behav Res Methods Instrum Comput | 2000 | 11029811 | Yes |
2048 | 2967 | 1483.5 | 64.15 | 32.1 | Escaping free-energy minima. | Alessandro Laio, Michele Parrinello | Proc Natl Acad Sci U S A | 2002 | 12271136 | Yes |
2049 | 19279 | 1483.0 | 502.12 | 38.6 | Clustal W and Clustal X version 2.0. | M A Larkin, G Blackshields, N P Brown, R Chenna, P A McGettigan, H McWilliam, F Valentin, I M Wallace, A Wilm, R Lopez, J D Thompson, T J Gibson, D G Higgins | Bioinformatics | 2007 | 17846036 | Yes |
2050 | 2965 | 1482.5 | 64.58 | 32.3 | Cellular senescence: when bad things happen to good cells. | Judith Campisi, Fabrizio d'Adda di Fagagna | Nat Rev Mol Cell Biol | 2007 | 17667954 | No |
2051 | 1482 | 1482.0 | 33.67 | 33.7 | Defective repair replication of DNA in xeroderma pigmentosum. | J E Cleaver | Nature | 1968 | 5655953 | Yes |
2052 | 1482 | 1482.0 | 5.68 | 5.7 | Chemoaffinity In The Orderly Growth Of Nerve Fiber Patterns And Connections. | R W Sperry | Proc Natl Acad Sci U S A | 1963 | 14077501 | Yes |
2053 | 10372 | 1481.7 | 221.54 | 31.6 | Embryonic stem cell lines derived from human blastocysts. | J A Thomson, J Itskovitz-Eldor, S S Shapiro, M A Waknitz, J J Swiergiel, V S Marshall, J M Jones | Science | 1998 | 9804556 | Yes |
2054 | 2963 | 1481.5 | 99.61 | 49.8 | How useful is SBF in predicting in vivo bone bioactivity? | Tadashi Kokubo, Hiroaki Takadama | Biomaterials | 2006 | 16448693 | No |
2055 | 1481 | 1481.0 | 45.9 | 45.9 | Superoxide dismutases. | I Fridovich | Annu Rev Biochem | 1975 | 1094908 | No |
2056 | 4442 | 1480.7 | 108.84 | 36.3 | Membrane lipids: where they are and how they behave. | Gerrit van Meer, Dennis R Voelker, Gerald W Feigenson | Nat Rev Mol Cell Biol | 2008 | 18216768 | No |
2057 | 2961 | 1480.5 | 82.24 | 41.1 | Genome regulation by long noncoding RNAs. | John L Rinn, Howard Y Chang | Annu Rev Biochem | 2012 | 22663078 | No |
2058 | 8882 | 1480.3 | 209.08 | 34.8 | Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. | Hadi Valadi, Karin Ekström, Apostolos Bossios, Margareta Sjöstrand, James J Lee, Jan O Lötvall | Nat Cell Biol | 2007 | 17486113 | Yes |
2059 | 1480 | 1480.0 | 65.4 | 65.4 | Human agency in social cognitive theory. | A Bandura | Am Psychol | 1989 | 2782727 | Yes |
2060 | 1480 | 1480.0 | 30.73 | 30.7 | Ionic blockage of sodium channels in nerve. | A M Woodhull | J Gen Physiol | 1973 | 4541078 | Yes |
2061 | 1480 | 1480.0 | 35.19 | 35.2 | Neuronal synchrony: a versatile code for the definition of relations? | W Singer | Neuron | 1999 | 10677026 | No |
2062 | 4439 | 1479.7 | 114.73 | 38.2 | How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. | R M Sapolsky, L M Romero, A U Munck | Endocr Rev | 2000 | 10696570 | No |
2063 | 2958 | 1479.0 | 76.68 | 38.3 | The expanding universe of T-cell subsets: Th1, Th2 and more. | T R Mosmann, S Sad | Immunol Today | 1996 | 8820272 | No |
2064 | 1479 | 1479.0 | 32.56 | 32.6 | The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes. | S E Kahn | Diabetologia | 2003 | 12637977 | No |
2065 | 1478 | 1478.0 | 33.84 | 33.8 | The cadherins: cell-cell adhesion molecules controlling animal morphogenesis. | M Takeichi | Development | 1988 | 3048970 | No |
2066 | 5908 | 1477.0 | 243.34 | 60.8 | A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. | M A Markwell, S M Haas, L L Bieber, N E Tolbert | Anal Biochem | 1978 | 98070 | Yes |
2067 | 1477 | 1477.0 | 26.13 | 26.1 | R factor transfer in Rhizobium leguminosarum. | J E Beringer | J Gen Microbiol | 1974 | 4612098 | Yes |
2068 | 1477 | 1477.0 | 34.74 | 34.7 | Oxidative stress in Parkinson's disease. | Peter Jenner | Ann Neurol | 2003 | 12666096 | No |
2069 | 4431 | 1477.0 | 74.03 | 24.7 | Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs. | C A Winter, E A Risley, G W Nuss | Proc Soc Exp Biol Med | 1962 | 14001233 | Yes |
2070 | 1477 | 1477.0 | 42.95 | 43.0 | Mitochondria and cancer. | Douglas C Wallace | Nat Rev Cancer | 2012 | 23001348 | No |
2071 | 2952 | 1476.0 | 115.96 | 58.0 | Assessment of eating disorders: interview or self-report questionnaire? | C G Fairburn, S J Beglin | Int J Eat Disord | 1994 | 7866415 | Yes |
2072 | 1476 | 1476.0 | 39.76 | 39.8 | A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE Task Force on Classification and Terminology. | J Engel | Epilepsia | 2001 | 11422340 | Yes |
2073 | 4427 | 1475.7 | 32.58 | 10.9 | The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes. | J T Dodge, C Mitchell, D J Hanahan | Arch Biochem Biophys | 1963 | 14028302 | Yes |
2074 | 8851 | 1475.2 | 261.26 | 43.5 | Cancer statistics, 2009. | Ahmedin Jemal, Rebecca Siegel, Elizabeth Ward, Yongping Hao, Jiaquan Xu, Michael J Thun | CA Cancer J Clin | 2009 | 19474385 | Yes |
2075 | 1475 | 1475.0 | 64.47 | 64.5 | Derivation and validation of a short-form oral health impact profile. | G D Slade | Community Dent Oral Epidemiol | 1997 | 9332805 | Yes |
2076 | 1475 | 1475.0 | 48.07 | 48.1 | Inflammation in atherosclerosis. | Peter Libby | Arterioscler Thromb Vasc Biol | 2012 | 22895665 | No |
2077 | 1474 | 1474.0 | 24.91 | 24.9 | Evidence For The Existence Of Monoamine Neurons In The Central Nervous System. Iv. Distribution Of Monoamine Nerve Terminals In The Central Nervous System. | K Fuxe | Acta Physiol Scand Suppl | 1965 | 14319769 | Yes |
2078 | 2947 | 1473.5 | 77.59 | 38.8 | A general method for isolation of high molecular weight DNA from eukaryotes. | N Blin, D W Stafford | Nucleic Acids Res | 1976 | 987581 | Yes |
2079 | 2947 | 1473.5 | 76.49 | 38.2 | Improvement of phylogenies after removing divergent and ambiguously aligned blocks from protein sequence alignments. | Gerard Talavera, Jose Castresana | Syst Biol | 2007 | 17654362 | Yes |
2080 | 1471 | 1471.0 | 70.54 | 70.5 | Chronic illness as biographical disruption. | M Bury | Sociol Health Illn | 1982 | 10260456 | Yes |
2081 | 1471 | 1471.0 | 38.53 | 38.5 | Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. | Michael F Holick | Am J Clin Nutr | 2004 | 15585788 | No |
2082 | 4411 | 1470.3 | 153.74 | 51.2 | CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. | Teresa C Horan, Mary Andrus, Margaret A Dudeck | Am J Infect Control | 2008 | 18538699 | No |
2083 | 1470 | 1470.0 | 37.14 | 37.1 | Interoception: the sense of the physiological condition of the body. | A D Craig | Curr Opin Neurobiol | 2003 | 12965300 | No |
2084 | 1469 | 1469.0 | 45.67 | 45.7 | The Neuropsychiatric Inventory: assessing psychopathology in dementia patients. | J L Cummings | Neurology | 1997 | 9153155 | No |
2085 | 1469 | 1469.0 | 7.64 | 7.6 | Electron Microscope Studies On The Structure Of Natural And Synthetic Protein Filaments From Striated Muscle. | H E Huxley | J Mol Biol | 1963 | 14064165 | Yes |
2086 | 2937 | 1468.5 | 74.98 | 37.5 | Abdominal obesity and metabolic syndrome. | Jean-Pierre Després, Isabelle Lemieux | Nature | 2006 | 17167477 | No |
2087 | 4402 | 1467.3 | 92.97 | 31.0 | TOR signaling in growth and metabolism. | Stephan Wullschleger, Robbie Loewith, Michael N Hall | Cell | 2006 | 16469695 | No |
2088 | 13204 | 1467.1 | 405.13 | 45.0 | The 1982 revised criteria for the classification of systemic lupus erythematosus. | E M Tan, A S Cohen, J F Fries, A T Masi, D J McShane, N F Rothfield, J G Schaller, N Talal, R J Winchester | Arthritis Rheum | 1982 | 7138600 | Yes |
2089 | 1467 | 1467.0 | 33.38 | 33.4 | Simple methods for "staining with lead" at high pH in electron microscopy. | M J Karnovsky | J Biophys Biochem Cytol | 1961 | 14454024 | Yes |
2090 | 1467 | 1467.0 | 36.08 | 36.1 | Fast and robust fixed-point algorithms for independent component analysis. | A Hyvärinen | IEEE Trans Neural Netw | 1999 | 18252563 | Yes |
2091 | 1466 | 1466.0 | 31.15 | 31.1 | Topoisomerase I inhibitors: camptothecins and beyond. | Yves Pommier | Nat Rev Cancer | 2006 | 16990856 | No |
2092 | 4397 | 1465.7 | 265.86 | 88.6 | SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules. | Antoine Daina, Olivier Michielin, Vincent Zoete | Sci Rep | 2017 | 28256516 | Yes |
2093 | 1465 | 1465.0 | 0.0 | 0.0 | Modality and topographic properties of single neurons of cat's somatic sensory cortex. | V B Mountcastle | J Neurophysiol | 1957 | 13439410 | Yes |
2094 | 1465 | 1465.0 | 0.0 | 0.0 | The free amino groups of insulin. | F Sanger | Biochem J | 1945 | 16747948 | Yes |
2095 | 2928 | 1464.0 | 456.21 | 228.1 | Interactive Tree Of Life (iTOL) v5: an online tool for phylogenetic tree display and annotation. | Ivica Letunic, Peer Bork | Nucleic Acids Res | 2021 | 33885785 | Yes |
2096 | 2927 | 1463.5 | 91.66 | 45.8 | Modified RECIST (mRECIST) assessment for hepatocellular carcinoma. | Riccardo Lencioni, Josep M Llovet | Semin Liver Dis | 2010 | 20175033 | No |
2097 | 1463 | 1463.0 | 33.94 | 33.9 | PPAR-gamma: adipogenic regulator and thiazolidinedione receptor. | B M Spiegelman | Diabetes | 1998 | 9568680 | No |
2098 | 5852 | 1463.0 | 128.19 | 32.0 | Probability-based protein identification by searching sequence databases using mass spectrometry data. | D N Perkins, D J Pappin, D M Creasy, J S Cottrell | Electrophoresis | 1999 | 10612281 | Yes |
2099 | 1463 | 1463.0 | 31.49 | 31.5 | Autophagy: from phenomenology to molecular understanding in less than a decade. | Daniel J Klionsky | Nat Rev Mol Cell Biol | 2007 | 17712358 | No |
2100 | 1462 | 1462.0 | 45.15 | 45.1 | Equipoise and the ethics of clinical research. | B Freedman | N Engl J Med | 1987 | 3600702 | Yes |
2101 | 2924 | 1462.0 | 86.35 | 43.2 | From best evidence to best practice: effective implementation of change in patients' care. | Richard Grol, Jeremy Grimshaw | Lancet | 2003 | 14568747 | No |
2102 | 1462 | 1462.0 | 0.0 | 0.0 | Methods of paper chromatography of steroids applicable to the study of steroids in mammalian blood and tissues. | I E Bush | Biochem J | 1952 | 14915960 | Yes |
2103 | 1462 | 1462.0 | 40.14 | 40.1 | Leishmaniasis: current situation and new perspectives. | P Desjeux | Comp Immunol Microbiol Infect Dis | 2004 | 15225981 | No |
2104 | 2922 | 1461.0 | 38.86 | 19.4 | The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation. | E G Gray, V P Whittaker | J Anat | 1962 | 13901297 | Yes |
2105 | 1461 | 1461.0 | 0.0 | 0.0 | The Function Of The Vertebral Veins And Their Role In The Spread Of Metastases. | O V Batson | Ann Surg | 1940 | 17857618 | Yes |
2106 | 1461 | 1461.0 | 73.13 | 73.1 | Neutrophil extracellular traps in immunity and disease. | Venizelos Papayannopoulos | Nat Rev Immunol | 2018 | 28990587 | No |
2107 | 1460 | 1460.0 | 34.43 | 34.4 | Binary Agrobacterium vectors for plant transformation. | M Bevan | Nucleic Acids Res | 1984 | 6095209 | Yes |
2108 | 1459 | 1459.0 | 36.03 | 36.0 | Microbial ecology of the gastrointestinal tract. | D C Savage | Annu Rev Microbiol | 1977 | 334036 | No |
2109 | 1458 | 1458.0 | 28.97 | 29.0 | The organization of proteins in the human red blood cell membrane. A review. | T L Steck | J Cell Biol | 1974 | 4600883 | No |
2110 | 1458 | 1458.0 | 26.64 | 26.6 | The Relation Of Recombination To Mutational Advance. | H J Muller | Mutat Res | 1964 | 14195748 | Yes |
2111 | 2914 | 1457.0 | 0.0 | 0.0 | Techniques for hemagglutination and hemagglutination-inhibition with arthropod-borne viruses. | D H Clarke, J Casals | Am J Trop Med Hyg | 1958 | 13571577 | Yes |
2112 | 2914 | 1457.0 | 85.84 | 42.9 | The cortical organization of speech processing. | Gregory Hickok, David Poeppel | Nat Rev Neurosci | 2007 | 17431404 | No |
2113 | 1456 | 1456.0 | 53.94 | 53.9 | Cardiac valve surgery--the "French correction". | A Carpentier | J Thorac Cardiovasc Surg | 1983 | 6887954 | Yes |
2114 | 1456 | 1456.0 | 33.67 | 33.7 | Phytohemagglutinin: an initiator of mitosis in cultures of normal human leukocytes. | P C Nowell | Cancer Res | 1960 | 14427849 | Yes |
2115 | 2910 | 1455.0 | 99.23 | 49.6 | Assay of proteins in the presence of interfering materials. | A Bensadoun, D Weinstein | Anal Biochem | 1976 | 1259145 | Yes |
2116 | 2909 | 1454.5 | 113.72 | 56.9 | Elements of cancer immunity and the cancer-immune set point. | Daniel S Chen, Ira Mellman | Nature | 2017 | 28102259 | No |
2117 | 1454 | 1454.0 | 19.59 | 19.6 | Codon--anticodon pairing: the wobble hypothesis. | F H Crick | J Mol Biol | 1966 | 5969078 | Yes |
2118 | 1454 | 1454.0 | 41.25 | 41.2 | The Hospital Anxiety And Depression Scale. | R Philip Snaith | Health Qual Life Outcomes | 2003 | 12914662 | Yes |
2119 | 1454 | 1454.0 | 0.0 | 0.0 | A modified ninhydrin colorimetric analysis for amino acids. | H Rosen | Arch Biochem Biophys | 1957 | 13412116 | Yes |
2120 | 1454 | 1454.0 | 32.98 | 33.0 | Cell signaling. H2O2, a necessary evil for cell signaling. | Sue Goo Rhee | Science | 2006 | 16809515 | Yes |
2121 | 1454 | 1454.0 | 0.0 | 0.0 | Potential, Impedance, And Rectification In Membranes. | D E Goldman | J Gen Physiol | 1943 | 19873371 | Yes |
2122 | 4360 | 1453.3 | 35.26 | 11.8 | Improved method for the determination of blood glutathione. | E Beutler, O Duron, B M Kelly | J Lab Clin Med | 1963 | 13967893 | Yes |
2123 | 4359 | 1453.0 | 94.92 | 31.6 | Telomeres shorten during ageing of human fibroblasts. | C B Harley, A B Futcher, C W Greider | Nature | 1990 | 2342578 | Yes |
2124 | 2906 | 1453.0 | 66.29 | 33.1 | Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA. | C Auffray, F Rougeon | Eur J Biochem | 1980 | 6772444 | Yes |
2125 | 2906 | 1453.0 | 85.03 | 42.5 | Mediation in experimental and nonexperimental studies: new procedures and recommendations. | Patrick E Shrout, Niall Bolger | Psychol Methods | 2002 | 12530702 | Yes |
2126 | 1453 | 1453.0 | 72.34 | 72.3 | International classification of sleep disorders-third edition: highlights and modifications. | Michael J Sateia | Chest | 2014 | 25367475 | No |
2127 | 4357 | 1452.3 | 109.62 | 36.5 | The metabolic syndrome. | Robert H Eckel, Scott M Grundy, Paul Z Zimmet | Lancet | 2005 | 15836891 | No |
2128 | 1452 | 1452.0 | 35.5 | 35.5 | General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids. | R A Houghten | Proc Natl Acad Sci U S A | 1985 | 2410914 | Yes |
2129 | 1452 | 1452.0 | 31.66 | 31.7 | Protein misfolding, evolution and disease. | C M Dobson | Trends Biochem Sci | 1999 | 10470028 | No |
2130 | 2903 | 1451.5 | 67.28 | 33.6 | The MAPK signaling cascade. | R Seger, E G Krebs | FASEB J | 1995 | 7601337 | No |
2131 | 2903 | 1451.5 | 57.89 | 28.9 | Intrinsically unstructured proteins and their functions. | H Jane Dyson, Peter E Wright | Nat Rev Mol Cell Biol | 2005 | 15738986 | No |
2132 | 2903 | 1451.5 | 60.38 | 30.2 | Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry. | Joshua E Elias, Steven P Gygi | Nat Methods | 2007 | 17327847 | Yes |
2133 | 1451 | 1451.0 | 48.43 | 48.4 | Analysis of radioligand binding experiments. A collection of computer programs for the IBM PC. | G A McPherson | J Pharmacol Methods | 1985 | 3840547 | Yes |
2134 | 1451 | 1451.0 | 36.26 | 36.3 | Stress and hippocampal plasticity. | B S McEwen | Annu Rev Neurosci | 1999 | 10202533 | No |
2135 | 1451 | 1451.0 | 30.49 | 30.5 | Neurotrophins as synaptic modulators. | M M Poo | Nat Rev Neurosci | 2001 | 11253356 | No |
2136 | 2902 | 1451.0 | 77.54 | 38.8 | Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. | B R Celli, W MacNee | Eur Respir J | 2004 | 15219010 | No |
2137 | 1451 | 1451.0 | 44.01 | 44.0 | The functional gastrointestinal disorders and the Rome III process. | Douglas A Drossman | Gastroenterology | 2006 | 16678553 | No |
2138 | 5803 | 1450.8 | 180.33 | 45.1 | The unlabeled antibody enzyme method of immunohistochemistry: preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes. | L A Sternberger, P H Hardy, J J Cuculis, H G Meyer | J Histochem Cytochem | 1970 | 4192899 | Yes |
2139 | 2900 | 1450.0 | 90.74 | 45.4 | Functional architecture of basal ganglia circuits: neural substrates of parallel processing. | G E Alexander, M D Crutcher | Trends Neurosci | 1990 | 1695401 | No |
2140 | 2900 | 1450.0 | 74.36 | 37.2 | Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. | I Issemann, S Green | Nature | 1990 | 2129546 | Yes |
2141 | 1450 | 1450.0 | 46.14 | 46.1 | A clinical method for assessing the ventilatory response to carbon dioxide. | D J Read | Australas Ann Med | 1967 | 6032026 | Yes |
2142 | 4350 | 1450.0 | 132.21 | 44.1 | Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. | S van der Linden, H A Valkenburg, A Cats | Arthritis Rheum | 1984 | 6231933 | Yes |
2143 | 2899 | 1449.5 | 94.37 | 47.2 | Peptidoglycan types of bacterial cell walls and their taxonomic implications. | K H Schleifer, O Kandler | Bacteriol Rev | 1972 | 4568761 | No |
2144 | 2899 | 1449.5 | 79.29 | 39.6 | A rapid boiling method for the preparation of bacterial plasmids. | D S Holmes, M Quigley | Anal Biochem | 1981 | 6269464 | Yes |
2145 | 1449 | 1449.0 | 49.7 | 49.7 | Assessing self-maintenance: activities of daily living, mobility, and instrumental activities of daily living. | S Katz | J Am Geriatr Soc | 1983 | 6418786 | No |
2146 | 2896 | 1448.0 | 72.09 | 36.0 | 3' non-coding region sequences in eukaryotic messenger RNA. | N J Proudfoot, G G Brownlee | Nature | 1976 | 822353 | Yes |
2147 | 1448 | 1448.0 | 33.53 | 33.5 | Developmental cell death: morphological diversity and multiple mechanisms. | P G Clarke | Anat Embryol (Berl) | 1990 | 2186664 | No |
2148 | 1448 | 1448.0 | 40.77 | 40.8 | Treatment of infections associated with surgical implants. | Rabih O Darouiche | N Engl J Med | 2004 | 15070792 | No |
2149 | 1448 | 1448.0 | 36.28 | 36.3 | Wound healing and its impairment in the diabetic foot. | Vincent Falanga | Lancet | 2005 | 16291068 | No |
2150 | 1448 | 1448.0 | 31.7 | 31.7 | Mitochondria: dynamic organelles in disease, aging, and development. | David C Chan | Cell | 2006 | 16814712 | No |
2151 | 4343 | 1447.7 | 92.63 | 30.9 | NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. | S Ghosh, M J May, E B Kopp | Annu Rev Immunol | 1998 | 9597130 | No |
2152 | 1447 | 1447.0 | 0.0 | 0.0 | Starch gel electrophoresis in a discontinous system of buffers. | M D Poulik | Nature | 1957 | 13493570 | Yes |
2153 | 13016 | 1446.2 | 400.24 | 44.5 | The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. | D V Sheehan, Y Lecrubier, K H Sheehan, P Amorim, J Janavs, E Weiller, T Hergueta, R Baker, G C Dunbar | J Clin Psychiatry | 1998 | 9881538 | No |
2154 | 1446 | 1446.0 | 35.5 | 35.5 | The amygdala modulates the consolidation of memories of emotionally arousing experiences. | James L McGaugh | Annu Rev Neurosci | 2004 | 15217324 | No |
2155 | 10118 | 1445.4 | 283.66 | 40.5 | BLAST+: architecture and applications. | Christiam Camacho, George Coulouris, Vahram Avagyan, Ning Ma, Jason Papadopoulos, Kevin Bealer, Thomas L Madden | BMC Bioinformatics | 2009 | 20003500 | Yes |
2156 | 1445 | 1445.0 | 42.42 | 42.4 | Human cardiovascular adjustments to exercise and thermal stress. | L B Rowell | Physiol Rev | 1974 | 4587247 | No |
2157 | 2888 | 1444.0 | 58.05 | 29.0 | A study of the factors affecting the aluminum oxide-trihydroxyindole procedure for the analysis of catecholamines. | A H Anton, D F Sayre | J Pharmacol Exp Ther | 1962 | 14013351 | Yes |
2158 | 2886 | 1443.0 | 109.57 | 54.8 | A new initiative on precision medicine. | Francis S Collins, Harold Varmus | N Engl J Med | 2015 | 25635347 | Yes |
2159 | 1442 | 1442.0 | 42.34 | 42.3 | Variations in patients' adherence to medical recommendations: a quantitative review of 50 years of research. | M Robin DiMatteo | Med Care | 2004 | 15076819 | Yes |
2160 | 1442 | 1442.0 | 50.32 | 50.3 | Phase retrieval algorithms: a comparison. | J R Fienup | Appl Opt | 1982 | 20396114 | Yes |
2161 | 2883 | 1441.5 | 85.87 | 42.9 | The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. | J D Hayes, D J Pulford | Crit Rev Biochem Mol Biol | 1995 | 8770536 | No |
2162 | 2883 | 1441.5 | 0.0 | 0.0 | Mutants of Escherichia coli requiring methionine or vitamin B12. | B D Davis, E S Mingioli | J Bacteriol | 1950 | 15436457 | Yes |
2163 | 1441 | 1441.0 | 74.21 | 74.2 | The determinants of parenting: a process model. | J Belsky | Child Dev | 1984 | 6705636 | Yes |
2164 | 1440 | 1440.0 | 37.29 | 37.3 | Capacitative calcium entry revisited. | J W Putney | Cell Calcium | 1990 | 1965707 | No |
2165 | 1439 | 1439.0 | 37.96 | 38.0 | Cell and environment interactions in tumor microregions: the multicell spheroid model. | R M Sutherland | Science | 1988 | 2451290 | Yes |
2166 | 1439 | 1439.0 | 56.82 | 56.8 | An outpatient program in behavioral medicine for chronic pain patients based on the practice of mindfulness meditation: theoretical considerations and preliminary results. | J Kabat-Zinn | Gen Hosp Psychiatry | 1982 | 7042457 | Yes |
2167 | 1439 | 1439.0 | 37.64 | 37.6 | The world health report 2002 - reducing risks, promoting healthy life. | J J Guilbert | Educ Health (Abingdon) | 2003 | 14741909 | Yes |
2168 | 1439 | 1439.0 | 117.9 | 117.9 | User's guide to correlation coefficients. | Haldun Akoglu | Turk J Emerg Med | 2018 | 30191186 | No |
2169 | 2877 | 1438.5 | 94.29 | 47.1 | The efficiency of systematic sampling in stereology and its prediction. | H J Gundersen, E B Jensen | J Microsc | 1987 | 3430576 | Yes |
2170 | 12945 | 1438.3 | 632.51 | 70.3 | Cancer statistics in China, 2015. | Wanqing Chen, Rongshou Zheng, Peter D Baade, Siwei Zhang, Hongmei Zeng, Freddie Bray, Ahmedin Jemal, Xue Qin Yu, Jie He | CA Cancer J Clin | 2016 | 26808342 | Yes |
2171 | 2876 | 1438.0 | 78.1 | 39.0 | Angiogenesis. | J Folkman, Y Shing | J Biol Chem | 1992 | 1375931 | No |
2172 | 1437 | 1437.0 | 56.37 | 56.4 | Reliability and factor analysis of the Epworth Sleepiness Scale. | M W Johns | Sleep | 1992 | 1519015 | Yes |
2173 | 1437 | 1437.0 | 34.63 | 34.6 | Origin, biogenesis, and activity of plant microRNAs. | Olivier Voinnet | Cell | 2009 | 19239888 | No |
2174 | 2872 | 1436.0 | 60.09 | 30.0 | The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. | M S Brown, J L Goldstein | Cell | 1997 | 9150132 | No |
2175 | 1436 | 1436.0 | 29.36 | 29.4 | Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. | S S Ferguson | Pharmacol Rev | 2001 | 11171937 | No |
2176 | 1435 | 1435.0 | 31.47 | 31.5 | DNA damage, aging, and cancer. | Jan H J Hoeijmakers | N Engl J Med | 2009 | 19812404 | No |
2177 | 1435 | 1435.0 | 59.15 | 59.1 | Working memory: theories, models, and controversies. | Alan Baddeley | Annu Rev Psychol | 2012 | 21961947 | No |
2178 | 2868 | 1434.0 | 91.49 | 45.7 | Synchronization of Plasmodium falciparum erythrocytic stages in culture. | C Lambros, J P Vanderberg | J Parasitol | 1979 | 383936 | Yes |
2179 | 2868 | 1434.0 | 0.0 | 0.0 | Histological grading and prognosis in breast cancer; a study of 1409 cases of which 359 have been followed for 15 years. | H J Bloom, W W Richardson | Br J Cancer | 1957 | 13499785 | Yes |
2180 | 15759 | 1432.6 | 416.51 | 37.9 | The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. | Aaron McKenna, Matthew Hanna, Eric Banks, Andrey Sivachenko, Kristian Cibulskis, Andrew Kernytsky, Kiran Garimella, David Altshuler, Stacey Gabriel, Mark Daly, Mark A DePristo | Genome Res | 2010 | 20644199 | Yes |
2181 | 2865 | 1432.5 | 67.45 | 33.7 | Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. | H Cai, D G Harrison | Circ Res | 2000 | 11073878 | No |
2182 | 2865 | 1432.5 | 0.0 | 0.0 | Brain stem reticular formation and activation of the EEG. | G Moruzzi, H W Magoun | Electroencephalogr Clin Neurophysiol | 1949 | 18421835 | Yes |
2183 | 1432 | 1432.0 | 34.13 | 34.1 | The use of nanocrystals in biological detection. | Paul Alivisatos | Nat Biotechnol | 2004 | 14704706 | Yes |
2184 | 1432 | 1432.0 | 40.24 | 40.2 | Graphene transistors. | Frank Schwierz | Nat Nanotechnol | 2010 | 20512128 | Yes |
2185 | 4295 | 1431.7 | 100.77 | 33.6 | Long non-coding RNAs: insights into functions. | Tim R Mercer, Marcel E Dinger, John S Mattick | Nat Rev Genet | 2009 | 19188922 | No |
2186 | 2861 | 1430.5 | 73.2 | 36.6 | Molecular replacement with MOLREP. | Alexei Vagin, Alexei Teplyakov | Acta Crystallogr D Biol Crystallogr | 2010 | 20057045 | Yes |
2187 | 2859 | 1429.5 | 54.11 | 27.1 | T-cell antigen receptor genes and T-cell recognition. | M M Davis, P J Bjorkman | Nature | 1988 | 3043226 | No |
2188 | 1429 | 1429.0 | 50.67 | 50.7 | The prevalence of 'alexithymic' characteristics in psychosomatic patients. | P E Sifneos | Psychother Psychosom | 1973 | 4770536 | Yes |
2189 | 1429 | 1429.0 | 42.52 | 42.5 | Strong localization of photons in certain disordered dielectric superlattices. | S John | Phys Rev Lett | 1987 | 10034761 | Yes |
2190 | 1429 | 1429.0 | 0.0 | 0.0 | A new readability yardstick. | R Flesch | J Appl Psychol | 1948 | 18867058 | Yes |
2191 | 7142 | 1428.4 | 153.31 | 30.7 | Site-directed mutagenesis by overlap extension using the polymerase chain reaction. | S N Ho, H D Hunt, R M Horton, J K Pullen, L R Pease | Gene | 1989 | 2744487 | Yes |
2192 | 1428 | 1428.0 | 47.81 | 47.8 | Gene flow and the geographic structure of natural populations. | M Slatkin | Science | 1987 | 3576198 | Yes |
2193 | 1428 | 1428.0 | 92.19 | 92.2 | The three column spine and its significance in the classification of acute thoracolumbar spinal injuries. | F Denis | Spine (Phila Pa 1976) | 1983 | 6670016 | Yes |
2194 | 1428 | 1428.0 | 49.61 | 49.6 | Colorimetric determination of phospholipids with ammonium ferrothiocyanate. | J C Stewart | Anal Biochem | 1980 | 6892980 | Yes |
2195 | 1428 | 1428.0 | 33.33 | 33.3 | Functions of ceramide in coordinating cellular responses to stress. | Y A Hannun | Science | 1996 | 8943189 | No |
2196 | 1427 | 1427.0 | 41.97 | 42.0 | Energy contributions of volatile fatty acids from the gastrointestinal tract in various species. | E N Bergman | Physiol Rev | 1990 | 2181501 | No |
2197 | 1427 | 1427.0 | 41.18 | 41.2 | The aging process. | D Harman | Proc Natl Acad Sci U S A | 1981 | 6947277 | Yes |
2198 | 4280 | 1426.7 | 84.01 | 28.0 | The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. | Fabio Martinon, Kimberly Burns, Jürg Tschopp | Mol Cell | 2002 | 12191486 | Yes |
2199 | 4279 | 1426.3 | 88.1 | 29.4 | Toll-like receptors. | Kiyoshi Takeda, Tsuneyasu Kaisho, Shizuo Akira | Annu Rev Immunol | 2003 | 12524386 | No |
2200 | 2851 | 1425.5 | 69.72 | 34.9 | Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. | E S Lander, D Botstein | Genetics | 1989 | 2563713 | Yes |
2201 | 1425 | 1425.0 | 41.64 | 41.6 | The fetal and infant origins of adult disease. | D J Barker | BMJ | 1990 | 2252919 | No |
2202 | 1425 | 1425.0 | 37.01 | 37.0 | Linked Functions And Reciprocal Effects In Hemoglobin: A Second Look. | J Wyman | Adv Protein Chem | 1964 | 14268785 | No |
2203 | 11396 | 1424.5 | 283.84 | 35.5 | Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. | N Tzourio-Mazoyer, B Landeau, D Papathanassiou, F Crivello, O Etard, N Delcroix, B Mazoyer, M Joliot | Neuroimage | 2002 | 11771995 | Yes |
2204 | 1424 | 1424.0 | 43.55 | 43.5 | Biological basis of the behavior of sick animals. | B L Hart | Neurosci Biobehav Rev | 1988 | 3050629 | No |
2205 | 1424 | 1424.0 | 40.8 | 40.8 | Recent developments in isocyanide based multicomponent reactions in applied chemistry. | Alexander Dömling | Chem Rev | 2006 | 16402771 | No |
2206 | 1423 | 1423.0 | 35.27 | 35.3 | The 'effective number of codons' used in a gene. | F Wright | Gene | 1990 | 2110097 | Yes |
2207 | 1423 | 1423.0 | 26.67 | 26.7 | Ubiquitin-dependent protein degradation. | M Hochstrasser | Annu Rev Genet | 1996 | 8982460 | No |
2208 | 2845 | 1422.5 | 55.05 | 27.5 | Autophagy as a regulated pathway of cellular degradation. | D J Klionsky, S D Emr | Science | 2000 | 11099404 | No |
2209 | 4267 | 1422.3 | 113.09 | 37.7 | Fast model-based estimation of ancestry in unrelated individuals. | David H Alexander, John Novembre, Kenneth Lange | Genome Res | 2009 | 19648217 | Yes |
2210 | 2843 | 1421.5 | 144.76 | 72.4 | A simple practice guide for dose conversion between animals and human. | Anroop B Nair, Shery Jacob | J Basic Clin Pharm | 2016 | 27057123 | No |
2211 | 2842 | 1421.0 | 96.51 | 48.3 | Selective loss of central cholinergic neurons in Alzheimer's disease. | P Davies, A J Maloney | Lancet | 1976 | 63862 | Yes |
2212 | 1421 | 1421.0 | 51.56 | 51.6 | Sodium ions, calcium ions, blood pressure regulation, and hypertension: a reassessment and a hypothesis. | M P Blaustein | Am J Physiol | 1977 | 324293 | No |
2213 | 1421 | 1421.0 | 93.34 | 93.3 | The Knee Society total knee arthroplasty roentgenographic evaluation and scoring system. | F C Ewald | Clin Orthop Relat Res | 1989 | 2805502 | Yes |
2214 | 1421 | 1421.0 | 25.72 | 25.7 | The DNA methyltransferases of mammals. | T H Bestor | Hum Mol Genet | 2000 | 11005794 | No |
2215 | 2840 | 1420.0 | 84.35 | 42.2 | Intracellular pH. | A Roos, W F Boron | Physiol Rev | 1981 | 7012859 | No |
2216 | 5679 | 1419.8 | 262.92 | 65.7 | Prevalence of childhood and adult obesity in the United States, 2011-2012. | Cynthia L Ogden, Margaret D Carroll, Brian K Kit, Katherine M Flegal | JAMA | 2014 | 24570244 | Yes |
2217 | 1419 | 1419.0 | 44.88 | 44.9 | Formation of glasses from liquids and biopolymers. | C A Angell | Science | 1995 | 17770101 | Yes |
2218 | 2837 | 1418.5 | 54.99 | 27.5 | Cancer genes and the pathways they control. | Bert Vogelstein, Kenneth W Kinzler | Nat Med | 2004 | 15286780 | No |
2219 | 1418 | 1418.0 | 41.07 | 41.1 | Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. | Charles A Dinarello | Blood | 2011 | 21304099 | No |
2220 | 5671 | 1417.8 | 165.42 | 41.4 | Reversible middle cerebral artery occlusion without craniectomy in rats. | E Z Longa, P R Weinstein, S Carlson, R Cummins | Stroke | 1989 | 2643202 | Yes |
2221 | 4251 | 1417.0 | 141.09 | 47.0 | Vascular endothelial cells synthesize nitric oxide from L-arginine. | R M Palmer, D S Ashton, S Moncada | Nature | 1988 | 3131684 | Yes |
2222 | 1417 | 1417.0 | 36.02 | 36.0 | Hemispheric asymmetry reduction in older adults: the HAROLD model. | Roberto Cabeza | Psychol Aging | 2002 | 11931290 | No |
2223 | 4251 | 1417.0 | 221.3 | 73.8 | Radiomics: Images Are More than Pictures, They Are Data. | Robert J Gillies, Paul E Kinahan, Hedvig Hricak | Radiology | 2016 | 26579733 | Yes |
2224 | 1416 | 1416.0 | 56.55 | 56.5 | Social phobia. | M R Liebowitz | Mod Probl Pharmacopsychiatry | 1987 | 2885745 | Yes |
2225 | 2832 | 1416.0 | 79.59 | 39.8 | Defining the clinical course of multiple sclerosis: results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. | F D Lublin, S C Reingold | Neurology | 1996 | 8780061 | Yes |
2226 | 2832 | 1416.0 | 119.34 | 59.7 | 3D bioprinting of tissues and organs. | Sean V Murphy, Anthony Atala | Nat Biotechnol | 2014 | 25093879 | Yes |
2227 | 16983 | 1415.2 | 714.78 | 59.6 | Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology. | Sue Richards, Nazneen Aziz, Sherri Bale, David Bick, Soma Das, Julie Gastier-Foster, Wayne W Grody, Madhuri Hegde, Elaine Lyon, Elaine Spector, Karl Voelkerding, Heidi L Rehm | Genet Med | 2015 | 25741868 | No |
2228 | 1415 | 1415.0 | 42.85 | 42.9 | Mate selection-a selection for a handicap. | A Zahavi | J Theor Biol | 1975 | 1195756 | Yes |
2229 | 1415 | 1415.0 | 35.32 | 35.3 | Solute perturbation of protein fluorescence. The quenching of the tryptophyl fluorescence of model compounds and of lysozyme by iodide ion. | S S Lehrer | Biochemistry | 1971 | 5119250 | Yes |
2230 | 1415 | 1415.0 | 33.47 | 33.5 | Proinflammatory cytokines. | C A Dinarello | Chest | 2000 | 10936147 | No |
2231 | 2830 | 1415.0 | 0.0 | 0.0 | Virus interference. I. The interferon. | A Isaacs, J Lindenmann | Proc R Soc Lond B Biol Sci | 1957 | 13465720 | Yes |
2232 | 5660 | 1415.0 | 144.4 | 36.1 | Microbial ecology: human gut microbes associated with obesity. | Ruth E Ley, Peter J Turnbaugh, Samuel Klein, Jeffrey I Gordon | Nature | 2006 | 17183309 | Yes |
2233 | 2829 | 1414.5 | 97.04 | 48.5 | The framing of decisions and the psychology of choice. | A Tversky, D Kahneman | Science | 1981 | 7455683 | Yes |
2234 | 2829 | 1414.5 | 72.04 | 36.0 | Morris water maze: procedures for assessing spatial and related forms of learning and memory. | Charles V Vorhees, Michael T Williams | Nat Protoc | 2006 | 17406317 | Yes |
2235 | 1414 | 1414.0 | 22.86 | 22.9 | Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis. | K S McCully | Am J Pathol | 1969 | 5792556 | Yes |
2236 | 2828 | 1414.0 | 56.48 | 28.2 | Short-term synaptic plasticity. | Robert S Zucker, Wade G Regehr | Annu Rev Physiol | 2002 | 11826273 | No |
2237 | 1413 | 1413.0 | 26.36 | 26.4 | NK cell receptors. | L L Lanier | Annu Rev Immunol | 1998 | 9597134 | No |
2238 | 1413 | 1413.0 | 33.19 | 33.2 | Predictive values of body mass index and waist circumference for risk factors of certain related diseases in Chinese adults--study on optimal cut-off points of body mass index and waist circumference in Chinese adults. | Bei-Fan Zhou | Biomed Environ Sci | 2002 | 12046553 | Yes |
2239 | 1413 | 1413.0 | 26.97 | 27.0 | The significance of responses of the genome to challenge. | B McClintock | Science | 1984 | 15739260 | No |
2240 | 1412 | 1412.0 | 32.19 | 32.2 | Nonaqueous liquid electrolytes for lithium-based rechargeable batteries. | Kang Xu | Chem Rev | 2004 | 15669157 | Yes |
2241 | 1411 | 1411.0 | 39.71 | 39.7 | Isolation and cultivation of Lyme disease spirochetes. | A G Barbour | Yale J Biol Med | 1984 | 6393604 | Yes |
2242 | 2822 | 1411.0 | 0.0 | 0.0 | The effect of sodium ions on the electrical activity of giant axon of the squid. | A L Hodgkin, B Katz | J Physiol | 1949 | 18128147 | Yes |
2243 | 1411 | 1411.0 | 42.24 | 42.2 | The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. | Artemis P Simopoulos | Exp Biol Med (Maywood) | 2008 | 18408140 | No |
2244 | 1410 | 1410.0 | 52.09 | 52.1 | Diversity in tropical rain forests and coral reefs. | J H Connell | Science | 1978 | 17840770 | Yes |
2245 | 2819 | 1409.5 | 67.77 | 33.9 | Decision curve analysis: a novel method for evaluating prediction models. | Andrew J Vickers, Elena B Elkin | Med Decis Making | 2006 | 17099194 | Yes |
2246 | 1409 | 1409.0 | 32.88 | 32.9 | Speculations on the functions of the major heat shock and glucose-regulated proteins. | H R Pelham | Cell | 1986 | 2944601 | Yes |
2247 | 1409 | 1409.0 | 59.44 | 59.4 | The self-medication hypothesis of addictive disorders: focus on heroin and cocaine dependence. | E J Khantzian | Am J Psychiatry | 1985 | 3904487 | No |
2248 | 1409 | 1409.0 | 48.13 | 48.1 | Quantitative Genetic Analysis Of Multivariate Evolution, Applied To Brain:Body Size Allometry. | Russell Lande | Evolution | 1979 | 28568194 | Yes |
2249 | 2817 | 1408.5 | 80.49 | 40.2 | Empirical predictions of protein conformation. | P Y Chou, G D Fasman | Annu Rev Biochem | 1978 | 354496 | No |
2250 | 1408 | 1408.0 | 33.54 | 33.5 | The basic science of gene therapy. | R C Mulligan | Science | 1993 | 8493530 | No |
2251 | 2815 | 1407.5 | 71.49 | 35.7 | A globally coherent fingerprint of climate change impacts across natural systems. | Camille Parmesan, Gary Yohe | Nature | 2003 | 12511946 | Yes |
2252 | 2815 | 1407.5 | 107.46 | 53.7 | Conn: a functional connectivity toolbox for correlated and anticorrelated brain networks. | Susan Whitfield-Gabrieli, Alfonso Nieto-Castanon | Brain Connect | 2012 | 22642651 | Yes |
2253 | 1407 | 1407.0 | 37.47 | 37.5 | A note on robust variance estimation for cluster-correlated data. | R L Williams | Biometrics | 2000 | 10877330 | Yes |
2254 | 1407 | 1407.0 | 35.82 | 35.8 | The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. | T Szkudelski | Physiol Res | 2001 | 11829314 | No |
2255 | 2813 | 1406.5 | 54.75 | 27.4 | Wnt signalling in stem cells and cancer. | Tannishtha Reya, Hans Clevers | Nature | 2005 | 15829953 | No |
2256 | 2812 | 1406.0 | 57.59 | 28.8 | 'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease? | George Davey Smith, Shah Ebrahim | Int J Epidemiol | 2003 | 12689998 | No |
2257 | 2811 | 1405.5 | 52.21 | 26.1 | Oncogenic kinase signalling. | P Blume-Jensen, T Hunter | Nature | 2001 | 11357143 | No |
2258 | 2810 | 1405.0 | 77.15 | 38.6 | Transforming growth factor beta in tissue fibrosis. | W A Border, N A Noble | N Engl J Med | 1994 | 7935686 | No |
2259 | 1404 | 1404.0 | 25.5 | 25.5 | Selection of successive tumour lines for metastasis. | I J Fidler | Nat New Biol | 1973 | 4512654 | Yes |
2260 | 1404 | 1404.0 | 61.31 | 61.3 | A New Weighting System For Mean Surface Temperature Of The Human Body. | N L Ramanathan | J Appl Physiol | 1964 | 14173555 | Yes |
2261 | 4212 | 1404.0 | 121.09 | 40.4 | Dose translation from animal to human studies revisited. | Shannon Reagan-Shaw, Minakshi Nihal, Nihal Ahmad | FASEB J | 2008 | 17942826 | Yes |
2262 | 4210 | 1403.3 | 146.32 | 48.8 | Structure-antioxidant activity relationships of flavonoids and phenolic acids. | C A Rice-Evans, N J Miller, G Paganga | Free Radic Biol Med | 1996 | 8743980 | Yes |
2263 | 2806 | 1403.0 | 87.75 | 43.9 | Performing the exact test of Hardy-Weinberg proportion for multiple alleles. | S W Guo, E A Thompson | Biometrics | 1992 | 1637966 | Yes |
2264 | 1403 | 1403.0 | 35.26 | 35.3 | Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides. | Y Shai | Biochim Biophys Acta | 1999 | 10590302 | No |
2265 | 1403 | 1403.0 | 36.69 | 36.7 | The epidemiology of venous thromboembolism. | Richard H White | Circulation | 2003 | 12814979 | No |
2266 | 1403 | 1403.0 | 50.43 | 50.4 | Categorical Data Analysis: Away from ANOVAs (transformation or not) and towards Logit Mixed Models. | T Florian Jaeger | J Mem Lang | 2008 | 19884961 | Yes |
2267 | 2805 | 1402.5 | 69.64 | 34.8 | Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule. | M D Pierschbacher, E Ruoslahti | Nature | 1984 | 6325925 | Yes |
2268 | 1402 | 1402.0 | 45.93 | 45.9 | Overcoming the absence of socioeconomic data in medical records: validation and application of a census-based methodology. | N Krieger | Am J Public Health | 1992 | 1566949 | Yes |
2269 | 1402 | 1402.0 | 36.04 | 36.0 | The intraclass correlation coefficient as a measure of reliability. | J J Bartko | Psychol Rep | 1966 | 5942109 | Yes |
2270 | 2804 | 1402.0 | 72.48 | 36.2 | Alternative activation of macrophages: mechanism and functions. | Siamon Gordon, Fernando O Martinez | Immunity | 2010 | 20510870 | No |
2271 | 1402 | 1402.0 | 40.65 | 40.6 | Breakthrough of the year 2013. Cancer immunotherapy. | Jennifer Couzin-Frankel | Science | 2013 | 24357284 | No |
2272 | 2803 | 1401.5 | 62.49 | 31.2 | Raster3D Version 2.0. A program for photorealistic molecular graphics. | E A Merritt, M E Murphy | Acta Crystallogr D Biol Crystallogr | 1994 | 15299354 | Yes |
2273 | 5605 | 1401.2 | 155.49 | 38.9 | Image quality assessment: from error visibility to structural similarity. | Zhou Wang, Alan Conrad Bovik, Hamid Rahim Sheikh, Eero P Simoncelli | IEEE Trans Image Process | 2004 | 15376593 | Yes |
2274 | 2802 | 1401.0 | 71.07 | 35.5 | CLUSTAL: a package for performing multiple sequence alignment on a microcomputer. | D G Higgins, P M Sharp | Gene | 1988 | 3243435 | Yes |
2275 | 1401 | 1401.0 | 38.93 | 38.9 | The debate over dopamine's role in reward: the case for incentive salience. | Kent C Berridge | Psychopharmacology (Berl) | 2007 | 17072591 | No |
2276 | 2801 | 1400.5 | 42.14 | 21.1 | Prediction of protein conformation. | P Y Chou, G D Fasman | Biochemistry | 1974 | 4358940 | Yes |
2277 | 1400 | 1400.0 | 32.04 | 32.0 | Protein kinase C: structure, function, and regulation. | A C Newton | J Biol Chem | 1995 | 7499357 | No |
2278 | 4199 | 1399.7 | 85.29 | 28.4 | Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM). | Michael J Rust, Mark Bates, Xiaowei Zhuang | Nat Methods | 2006 | 16896339 | Yes |
2279 | 2799 | 1399.5 | 61.59 | 30.8 | An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. | A A Beg, D Baltimore | Science | 1996 | 8864118 | Yes |
2280 | 1399 | 1399.0 | 62.53 | 62.5 | Adjustments to Zatsiorsky-Seluyanov's segment inertia parameters. | P de Leva | J Biomech | 1996 | 8872282 | Yes |
2281 | 1398 | 1398.0 | 50.31 | 50.3 | The SPQ: a scale for the assessment of schizotypal personality based on DSM-III-R criteria. | A Raine | Schizophr Bull | 1991 | 1805349 | Yes |
2282 | 2796 | 1398.0 | 69.79 | 34.9 | Molecular beacons: probes that fluoresce upon hybridization. | S Tyagi, F R Kramer | Nat Biotechnol | 1996 | 9630890 | Yes |
2283 | 2795 | 1397.5 | 61.93 | 31.0 | The pathophysiology and treatment of sepsis. | Richard S Hotchkiss, Irene E Karl | N Engl J Med | 2003 | 12519925 | No |
2284 | 8382 | 1397.0 | 215.22 | 35.9 | Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. | Roy G Brower, Michael A Matthay, Alan Morris, David Schoenfeld, B Taylor Thompson, Arthur Wheeler | N Engl J Med | 2000 | 10793162 | Yes |
2285 | 1397 | 1397.0 | 60.64 | 60.6 | Periodontitis: from microbial immune subversion to systemic inflammation. | George Hajishengallis | Nat Rev Immunol | 2015 | 25534621 | No |
2286 | 2793 | 1396.5 | 121.09 | 60.5 | Sex differences in immune responses. | Sabra L Klein, Katie L Flanagan | Nat Rev Immunol | 2016 | 27546235 | No |
2287 | 1396 | 1396.0 | 28.05 | 28.1 | The Interaction of Selection and Linkage. I. General Considerations; Heterotic Models. | R C Lewontin | Genetics | 1964 | 17248194 | Yes |
2288 | 2789 | 1394.5 | 82.54 | 41.3 | Glycine potentiates the NMDA response in cultured mouse brain neurons. | J W Johnson, P Ascher | Nature | 1987 | 2433595 | Yes |
2289 | 2789 | 1394.5 | 88.74 | 44.4 | Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art. | Johan W S Vlaeyen, Steven J Linton | Pain | 2000 | 10781906 | No |
2290 | 2788 | 1394.0 | 86.28 | 43.1 | Unidentified curved bacilli on gastric epithelium in active chronic gastritis. | J R Warren, B Marshall | Lancet | 1983 | 6134060 | Yes |
2291 | 1394 | 1394.0 | 30.57 | 30.6 | The ATP synthase--a splendid molecular machine. | P D Boyer | Annu Rev Biochem | 1997 | 9242922 | No |
2292 | 1394 | 1394.0 | 33.37 | 33.4 | Drug-induced prolongation of the QT interval. | Dan M Roden | N Engl J Med | 2004 | 14999113 | No |
2293 | 2785 | 1392.5 | 82.28 | 41.1 | Microdetermination of long-chain fatty acids in plasma and tissues. | V P Dole, H Meinertz | J Biol Chem | 1960 | 13817286 | Yes |
2294 | 2784 | 1392.0 | 72.86 | 36.4 | Enzyme-linked immunosorbent assay (ELISA). Quantitative assay of immunoglobulin G. | E Engvall, P Perlmann | Immunochemistry | 1971 | 5135623 | Yes |
2295 | 1392 | 1392.0 | 52.79 | 52.8 | Presidential address, 1980. Surprise!...Surprise? | E Donchin | Psychophysiology | 1981 | 7280146 | Yes |
2296 | 1392 | 1392.0 | 24.18 | 24.2 | The economics of ribosome biosynthesis in yeast. | J R Warner | Trends Biochem Sci | 1999 | 10542411 | No |
2297 | 2784 | 1392.0 | 110.78 | 55.4 | Cisplatin in cancer therapy: molecular mechanisms of action. | Shaloam Dasari, Paul Bernard Tchounwou | Eur J Pharmacol | 2014 | 25058905 | No |
2298 | 2782 | 1391.0 | 149.12 | 74.6 | Social networks, host resistance, and mortality: a nine-year follow-up study of Alameda County residents. | L F Berkman, S L Syme | Am J Epidemiol | 1979 | 425958 | Yes |
2299 | 1391 | 1391.0 | 50.11 | 50.1 | Quantitative methods in the review of epidemiologic literature. | S Greenland | Epidemiol Rev | 1987 | 3678409 | Yes |
2300 | 1391 | 1391.0 | 27.04 | 27.0 | Natively unfolded proteins: a point where biology waits for physics. | Vladimir N Uversky | Protein Sci | 2002 | 11910019 | No |
2301 | 1389 | 1389.0 | 29.6 | 29.6 | Cancer of the ovary. | Stephen A Cannistra | N Engl J Med | 2004 | 15590954 | No |
2302 | 2777 | 1388.5 | 84.32 | 42.2 | An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. | O Johnell, J A Kanis | Osteoporos Int | 2006 | 16983459 | Yes |
2303 | 2776 | 1388.0 | 80.33 | 40.2 | CLUMPP: a cluster matching and permutation program for dealing with label switching and multimodality in analysis of population structure. | Mattias Jakobsson, Noah A Rosenberg | Bioinformatics | 2007 | 17485429 | Yes |
2304 | 4163 | 1387.7 | 100.36 | 33.5 | Wnt/beta-catenin signaling: components, mechanisms, and diseases. | Bryan T MacDonald, Keiko Tamai, Xi He | Dev Cell | 2009 | 19619488 | No |
2305 | 1387 | 1387.0 | 28.3 | 28.3 | Origin of concatemeric T7 DNA. | J D Watson | Nat New Biol | 1972 | 4507727 | Yes |
2306 | 2773 | 1386.5 | 88.69 | 44.3 | The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. | W R Gibb, A J Lees | J Neurol Neurosurg Psychiatry | 1988 | 2841426 | No |
2307 | 2773 | 1386.5 | 63.5 | 31.8 | A method of trace iodination of proteins for immunologic studies. | P J McConahey, F J Dixon | Int Arch Allergy Appl Immunol | 1966 | 4160044 | Yes |
2308 | 2773 | 1386.5 | 65.54 | 32.8 | Inflammation, stress, and diabetes. | Kathryn E Wellen, Gökhan S Hotamisligil | J Clin Invest | 2005 | 15864338 | No |
2309 | 1386 | 1386.0 | 33.77 | 33.8 | Tobacco smoke carcinogens and lung cancer. | S S Hecht | J Natl Cancer Inst | 1999 | 10413421 | No |
2310 | 2772 | 1386.0 | 62.15 | 31.1 | Immunoassay of endogenous plasma insulin in man. | R S Yalow, S A Berson | J Clin Invest | 1960 | 13846364 | Yes |
2311 | 1386 | 1386.0 | 34.65 | 34.6 | The cancer stem cell: premises, promises and challenges. | Hans Clevers | Nat Med | 2011 | 21386835 | No |
2312 | 2772 | 1386.0 | 68.96 | 34.5 | Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications. | Felix Krueger, Simon R Andrews | Bioinformatics | 2011 | 21493656 | Yes |
2313 | 1386 | 1386.0 | 62.7 | 62.7 | Mechanisms linking social ties and support to physical and mental health. | Peggy A Thoits | J Health Soc Behav | 2011 | 21673143 | No |
2314 | 2771 | 1385.5 | 71.34 | 35.7 | A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments. | J Messing, J Vieira | Gene | 1982 | 6295880 | Yes |
2315 | 1385 | 1385.0 | 30.12 | 30.1 | Target-oriented and diversity-oriented organic synthesis in drug discovery. | S L Schreiber | Science | 2000 | 10720315 | No |
2316 | 4155 | 1385.0 | 120.16 | 40.1 | Validation of the Insomnia Severity Index as an outcome measure for insomnia research. | C H. Bastien, A Vallières, C M. Morin | Sleep Med | 2001 | 11438246 | Yes |
2317 | 4153 | 1384.3 | 194.18 | 64.7 | Risk factors for falls among elderly persons living in the community. | M E Tinetti, M Speechley, S F Ginter | N Engl J Med | 1988 | 3205267 | Yes |
2318 | 1384 | 1384.0 | 35.05 | 35.0 | Diagnosis of osteoporosis and assessment of fracture risk. | John A Kanis | Lancet | 2002 | 12057569 | No |
2319 | 5536 | 1384.0 | 204.36 | 51.1 | FieldTrip: Open source software for advanced analysis of MEG, EEG, and invasive electrophysiological data. | Robert Oostenveld, Pascal Fries, Eric Maris, Jan-Mathijs Schoffelen | Comput Intell Neurosci | 2011 | 21253357 | Yes |
2320 | 4151 | 1383.7 | 111.2 | 37.1 | TCS: a computer program to estimate gene genealogies. | M Clement, D Posada, K A Crandall | Mol Ecol | 2000 | 11050560 | Yes |
2321 | 1383 | 1383.0 | 46.5 | 46.5 | Interleukin-1. | C A Dinarello | Rev Infect Dis | 1984 | 6369481 | No |
2322 | 4149 | 1383.0 | 87.79 | 29.3 | Multidrug resistance in cancer: role of ATP-dependent transporters. | Michael M Gottesman, Tito Fojo, Susan E Bates | Nat Rev Cancer | 2002 | 11902585 | No |
2323 | 2766 | 1383.0 | 67.22 | 33.6 | Powering the planet: chemical challenges in solar energy utilization. | Nathan S Lewis, Daniel G Nocera | Proc Natl Acad Sci U S A | 2006 | 17043226 | Yes |
2324 | 1382 | 1382.0 | 0.0 | 0.0 | Intracellular distribution of enzymes; the oxidation of octanoic acid by rat liver fractions. | W C Schneider | J Biol Chem | 1948 | 18886166 | Yes |
2325 | 1381 | 1381.0 | 18.7 | 18.7 | Hippocampal electrical activity and voluntary movement in the rat. | C H Vanderwolf | Electroencephalogr Clin Neurophysiol | 1969 | 4183562 | Yes |
2326 | 1381 | 1381.0 | 31.16 | 31.2 | Molecular basis of long-term plasticity underlying addiction. | E J Nestler | Nat Rev Neurosci | 2001 | 11252991 | No |
2327 | 4139 | 1379.7 | 83.73 | 27.9 | The versatility and universality of calcium signalling. | M J Berridge, P Lipp, M D Bootman | Nat Rev Mol Cell Biol | 2000 | 11413485 | No |
2328 | 1379 | 1379.0 | 30.62 | 30.6 | Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles. | M Kozak | Microbiol Rev | 1983 | 6343825 | No |
2329 | 1379 | 1379.0 | 35.94 | 35.9 | Genetic consequences of climatic oscillations in the Quaternary. | G M Hewitt | Philos Trans R Soc Lond B Biol Sci | 2004 | 15101575 | No |
2330 | 1379 | 1379.0 | 44.17 | 44.2 | The role of autophagy in neurodegenerative disease. | Ralph A Nixon | Nat Med | 2013 | 23921753 | No |
2331 | 2757 | 1378.5 | 80.82 | 40.4 | Physiological time-series analysis using approximate entropy and sample entropy. | J S Richman, J R Moorman | Am J Physiol Heart Circ Physiol | 2000 | 10843903 | Yes |
2332 | 1378 | 1378.0 | 58.83 | 58.8 | Refinement of the coomassie blue method of protein quantitation. A simple and linear spectrophotometric assay for less than or equal to 0.5 to 50 microgram of protein. | T Spector | Anal Biochem | 1978 | 655375 | Yes |
2333 | 6890 | 1378.0 | 254.74 | 50.9 | Evidence based medicine: what it is and what it isn't. | D L Sackett, W M Rosenberg, J A Gray, R B Haynes, W S Richardson | BMJ | 1996 | 8555924 | No |
2334 | 2756 | 1378.0 | 80.01 | 40.0 | Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. | C J Murray, A D Lopez | Lancet | 1997 | 9164317 | Yes |
2335 | 1377 | 1377.0 | 29.31 | 29.3 | A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. | Dale R Nyholt | Am J Hum Genet | 2004 | 14997420 | Yes |
2336 | 2753 | 1376.5 | 95.24 | 47.6 | A new scale of social desirability independent of psychopathology. | D P Crowne, D Marlowe | J Consult Psychol | 1960 | 13813058 | Yes |
2337 | 4128 | 1376.0 | 136.52 | 45.5 | Global estimates of the prevalence of diabetes for 2010 and 2030. | J E Shaw, R A Sicree, P Z Zimmet | Diabetes Res Clin Pract | 2010 | 19896746 | Yes |
2338 | 2752 | 1376.0 | 109.37 | 54.7 | Natural products as sources of new drugs over the 30 years from 1981 to 2010. | David J Newman, Gordon M Cragg | J Nat Prod | 2012 | 22316239 | No |
2339 | 4127 | 1375.7 | 140.48 | 46.8 | Factor structure of the Barratt impulsiveness scale. | J H Patton, M S Stanford, E S Barratt | J Clin Psychol | 1995 | 8778124 | Yes |
2340 | 2751 | 1375.5 | 99.26 | 49.6 | Biology of disease: free radicals and tissue injury. | B A Freeman, J D Crapo | Lab Invest | 1982 | 6290784 | No |
2341 | 4126 | 1375.3 | 98.32 | 32.8 | Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. | Daniel Falush, Matthew Stephens, Jonathan K Pritchard | Genetics | 2003 | 12930761 | Yes |
2342 | 4126 | 1375.3 | 91.95 | 30.7 | OrthoMCL: identification of ortholog groups for eukaryotic genomes. | Li Li, Christian J Stoeckert, David S Roos | Genome Res | 2003 | 12952885 | Yes |
2343 | 1375 | 1375.0 | 24.33 | 24.3 | The snail superfamily of zinc-finger transcription factors. | M Angela Nieto | Nat Rev Mol Cell Biol | 2002 | 11994736 | No |
2344 | 1374 | 1374.0 | 21.78 | 21.8 | Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction. | J R David | Proc Natl Acad Sci U S A | 1966 | 5229858 | Yes |
2345 | 2748 | 1374.0 | 70.32 | 35.2 | Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins. | D Marion, K Wüthrich | Biochem Biophys Res Commun | 1983 | 6307308 | Yes |
2346 | 1373 | 1373.0 | 28.34 | 28.3 | Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators. | R I Morimoto | Genes Dev | 1998 | 9869631 | No |
2347 | 2746 | 1373.0 | 73.74 | 36.9 | Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. | Robert E W Hancock, Hans-Georg Sahl | Nat Biotechnol | 2006 | 17160061 | No |
2348 | 1373 | 1373.0 | 57.03 | 57.0 | The global burden of IBD: from 2015 to 2025. | Gilaad G Kaplan | Nat Rev Gastroenterol Hepatol | 2015 | 26323879 | No |
2349 | 5491 | 1372.8 | 211.81 | 53.0 | Bayesian phylogenetics with BEAUti and the BEAST 1.7. | Alexei J Drummond, Marc A Suchard, Dong Xie, Andrew Rambaut | Mol Biol Evol | 2012 | 22367748 | Yes |
2350 | 8233 | 1372.2 | 269.83 | 45.0 | Antioxidant activity applying an improved ABTS radical cation decolorization assay. | R Re, N Pellegrini, A Proteggente, A Pannala, M Yang, C Rice-Evans | Free Radic Biol Med | 1999 | 10381194 | Yes |
2351 | 1372 | 1372.0 | 39.11 | 39.1 | Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation. | P Willner | Psychopharmacology (Berl) | 1997 | 9452163 | No |
2352 | 1372 | 1372.0 | 0.0 | 0.0 | An improved procedure for starch-gel electrophoresis: further variations in the serum proteins of normal individuals. | O Smithies | Biochem J | 1959 | 13638269 | Yes |
2353 | 1372 | 1372.0 | 35.28 | 35.3 | The human orbitofrontal cortex: linking reward to hedonic experience. | Morten L Kringelbach | Nat Rev Neurosci | 2005 | 16136173 | No |
2354 | 1372 | 1372.0 | 43.55 | 43.5 | Amino acids: metabolism, functions, and nutrition. | Guoyao Wu | Amino Acids | 2009 | 19301095 | No |
2355 | 2743 | 1371.5 | 55.22 | 27.6 | Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids. | A J Berk, P A Sharp | Cell | 1977 | 922889 | Yes |
2356 | 2742 | 1371.0 | 77.32 | 38.7 | Mortality by cause for eight regions of the world: Global Burden of Disease Study. | C J Murray, A D Lopez | Lancet | 1997 | 9142060 | Yes |
2357 | 1371 | 1371.0 | 31.95 | 31.9 | Huntington's disease. | Francis O Walker | Lancet | 2007 | 17240289 | No |
2358 | 1370 | 1370.0 | 42.43 | 42.4 | The projections of the ventral tegmental area and adjacent regions: a combined fluorescent retrograde tracer and immunofluorescence study in the rat. | L W Swanson | Brain Res Bull | 1982 | 6816390 | Yes |
2359 | 1370 | 1370.0 | 32.21 | 32.2 | Regulation of differentiation of vascular smooth muscle cells. | G K Owens | Physiol Rev | 1995 | 7624392 | No |
2360 | 1370 | 1370.0 | 0.0 | 0.0 | The generalisation of student's problems when several different population variances are involved. | B L Welch | Biometrika | 1947 | 20287819 | Yes |
2361 | 4109 | 1369.7 | 117.95 | 39.3 | Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins. | J Garnier, D J Osguthorpe, B Robson | J Mol Biol | 1978 | 642007 | Yes |
2362 | 1369 | 1369.0 | 39.88 | 39.9 | Depression in late life: review and commentary. | Dan G Blazer | J Gerontol A Biol Sci Med Sci | 2003 | 12634292 | No |
2363 | 1369 | 1369.0 | 54.1 | 54.1 | AliView: a fast and lightweight alignment viewer and editor for large datasets. | Anders Larsson | Bioinformatics | 2014 | 25095880 | Yes |
2364 | 1368 | 1368.0 | 47.01 | 47.0 | Multiple calcium channels and neuronal function. | R J Miller | Science | 1987 | 2432656 | No |
2365 | 1368 | 1368.0 | 25.92 | 25.9 | Epithelial-mesenchymal transitions in development and pathologies. | Jean Paul Thiery | Curr Opin Cell Biol | 2003 | 14644200 | No |
2366 | 2735 | 1367.5 | 67.87 | 33.9 | Myocardial reperfusion injury. | Derek M Yellon, Derek J Hausenloy | N Engl J Med | 2007 | 17855673 | No |
2367 | 2734 | 1367.0 | 85.18 | 42.6 | A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. | R L Juliano, V Ling | Biochim Biophys Acta | 1976 | 990323 | Yes |
2368 | 2734 | 1367.0 | 70.93 | 35.5 | EasySpin, a comprehensive software package for spectral simulation and analysis in EPR. | Stefan Stoll, Arthur Schweiger | J Magn Reson | 2006 | 16188474 | Yes |
2369 | 1367 | 1367.0 | 44.22 | 44.2 | Synopsis of some recent tactical application of bioisosteres in drug design. | Nicholas A Meanwell | J Med Chem | 2011 | 21413808 | Yes |
2370 | 1367 | 1367.0 | 64.91 | 64.9 | PLATON SQUEEZE: a tool for the calculation of the disordered solvent contribution to the calculated structure factors. | Anthony L Spek | Acta Crystallogr C Struct Chem | 2015 | 25567569 | Yes |
2371 | 6833 | 1366.6 | 198.46 | 39.7 | Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. | Ronald C Kessler, Wai Tat Chiu, Olga Demler, Kathleen R Merikangas, Ellen E Walters | Arch Gen Psychiatry | 2005 | 15939839 | Yes |
2372 | 2733 | 1366.5 | 93.18 | 46.6 | Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans. | D H Figurski, D R Helinski | Proc Natl Acad Sci U S A | 1979 | 377280 | Yes |
2373 | 2731 | 1365.5 | 81.7 | 40.9 | Estimating wealth effects without expenditure data--or tears: an application to educational enrollments in states of India. | D Filmer, L H Pritchett | Demography | 2001 | 11227840 | Yes |
2374 | 1365 | 1365.0 | 22.33 | 22.3 | Cancer. Addiction to oncogenes--the Achilles heal of cancer. | I Bernard Weinstein | Science | 2002 | 12098689 | No |
2375 | 1365 | 1365.0 | 37.31 | 37.3 | The pollution of the marine environment by plastic debris: a review. | José G B Derraik | Mar Pollut Bull | 2002 | 12405208 | No |
2376 | 2728 | 1364.0 | 72.99 | 36.5 | Antibiotic resistance of bacteria in biofilms. | P S Stewart, J W Costerton | Lancet | 2001 | 11463434 | No |
2377 | 1364 | 1364.0 | 48.92 | 48.9 | The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles. | Eleonore Fröhlich | Int J Nanomedicine | 2012 | 23144561 | No |
2378 | 1363 | 1363.0 | 49.63 | 49.6 | The structure of beta-lactamases. | R P Ambler | Philos Trans R Soc Lond B Biol Sci | 1980 | 6109327 | Yes |
2379 | 1363 | 1363.0 | 0.0 | 0.0 | Effects of varying the vehicle for OsO4 in tissue fixation. | J B Caulfield | J Biophys Biochem Cytol | 1957 | 13475399 | Yes |
2380 | 2723 | 1361.5 | 80.11 | 40.1 | The Measurement Of Selection On Correlated Characters. | Russell Lande, Stevan J Arnold | Evolution | 1983 | 28556011 | Yes |
2381 | 1361 | 1361.0 | 32.75 | 32.8 | Membrane protein structure prediction. Hydrophobicity analysis and the positive-inside rule. | G von Heijne | J Mol Biol | 1992 | 1593632 | Yes |
2382 | 1361 | 1361.0 | 64.44 | 64.4 | Molecular pathology of schizophrenia: more than one disease process? | T J Crow | Br Med J | 1980 | 6101544 | No |
2383 | 1361 | 1361.0 | 28.04 | 28.0 | Stability and flexibility of epigenetic gene regulation in mammalian development. | Wolf Reik | Nature | 2007 | 17522676 | No |
2384 | 1361 | 1361.0 | 41.0 | 41.0 | Cross-dehydrogenative coupling (CDC): exploring C-C bond formations beyond functional group transformations. | Chao-Jun Li | Acc Chem Res | 2009 | 19220064 | Yes |
2385 | 2721 | 1360.5 | 52.22 | 26.1 | A protein sequenator. | P Edman, G Begg | Eur J Biochem | 1967 | 6059350 | Yes |
2386 | 2720 | 1360.0 | 54.02 | 27.0 | Prediction of complete gene structures in human genomic DNA. | C Burge, S Karlin | J Mol Biol | 1997 | 9149143 | Yes |
2387 | 2720 | 1360.0 | 57.81 | 28.9 | LTP and LTD: an embarrassment of riches. | Robert C Malenka, Mark F Bear | Neuron | 2004 | 15450156 | No |
2388 | 1360 | 1360.0 | 34.28 | 34.3 | Mitochondrial fusion and fission in cell life and death. | Benedikt Westermann | Nat Rev Mol Cell Biol | 2010 | 21102612 | No |
2389 | 2719 | 1359.5 | 95.53 | 47.8 | A sensitive silver stain for detecting lipopolysaccharides in polyacrylamide gels. | C M Tsai, C E Frasch | Anal Biochem | 1982 | 6176137 | Yes |
2390 | 2718 | 1359.0 | 74.8 | 37.4 | miRBase: integrating microRNA annotation and deep-sequencing data. | Ana Kozomara, Sam Griffiths-Jones | Nucleic Acids Res | 2011 | 21037258 | Yes |
2391 | 2716 | 1358.0 | 62.56 | 31.3 | NF-kappa B: ten years after. | P A Baeuerle, D Baltimore | Cell | 1996 | 8858144 | No |
2392 | 1358 | 1358.0 | 31.26 | 31.3 | Two's company, three's a crowd: can H2S be the third endogenous gaseous transmitter? | Rui Wang | FASEB J | 2002 | 12409322 | Yes |
2393 | 1358 | 1358.0 | 12.1 | 12.1 | Immunological function of the thymus. | J F Miller | Lancet | 1961 | 14474038 | Yes |
2394 | 1357 | 1357.0 | 27.16 | 27.2 | Dimerization of cell surface receptors in signal transduction. | C H Heldin | Cell | 1995 | 7834741 | No |
2395 | 2714 | 1357.0 | 55.34 | 27.7 | Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. | J M Kyriakis, J Avruch | Physiol Rev | 2001 | 11274345 | No |
2396 | 1357 | 1357.0 | 35.86 | 35.9 | Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications. | P Lips | Endocr Rev | 2001 | 11493580 | No |
2397 | 1357 | 1357.0 | 24.2 | 24.2 | Chromatin modification and epigenetic reprogramming in mammalian development. | En Li | Nat Rev Genet | 2002 | 12209141 | No |
2398 | 2714 | 1357.0 | 0.0 | 0.0 | The respiratory chain and oxidative phosphorylation. | B Chance, G R Williams | Adv Enzymol Relat Subj Biochem | 1956 | 13313307 | Yes |
2399 | 1356 | 1356.0 | 29.97 | 30.0 | Diarylethenes for Memories and Switches. | Masahiro Irie | Chem Rev | 2000 | 11777416 | Yes |
2400 | 2711 | 1355.5 | 66.38 | 33.2 | Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. | M P Lutolf, J A Hubbell | Nat Biotechnol | 2005 | 15637621 | No |
2401 | 1355 | 1355.0 | 52.86 | 52.9 | Blood gas calculator. | J W Severinghaus | J Appl Physiol | 1966 | 5912737 | Yes |
2402 | 1355 | 1355.0 | 42.77 | 42.8 | Antecedent- and response-focused emotion regulation: divergent consequences for experience, expression, and physiology. | J J Gross | J Pers Soc Psychol | 1998 | 9457784 | Yes |
2403 | 4063 | 1354.3 | 90.82 | 30.3 | Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides. | Christian W Tornøe, Caspar Christensen, Morten Meldal | J Org Chem | 2002 | 11975567 | Yes |
2404 | 1354 | 1354.0 | 42.9 | 42.9 | Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: a hypothesis for the etiology of schizophrenia. | A A Grace | Neuroscience | 1991 | 1676137 | No |
2405 | 1354 | 1354.0 | 26.18 | 26.2 | The origin of the genetic code. | F H Crick | J Mol Biol | 1968 | 4887876 | Yes |
2406 | 2708 | 1354.0 | 62.51 | 31.3 | Emerging roles of caspase-3 in apoptosis. | A G Porter, R U Jänicke | Cell Death Differ | 1999 | 10200555 | No |
2407 | 6766 | 1353.2 | 165.0 | 33.0 | Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. | Sarah Lewington, Robert Clarke, Nawab Qizilbash, Richard Peto, Rory Collins | Lancet | 2002 | 12493255 | Yes |
2408 | 1353 | 1353.0 | 34.62 | 34.6 | The carbon dioxide hydration activity of carbonic anhydrase. I. Stop-flow kinetic studies on the native human isoenzymes B and C. | R G Khalifah | J Biol Chem | 1971 | 4994926 | Yes |
2409 | 1353 | 1353.0 | 43.38 | 43.4 | History of the Rochester Epidemiology Project. | L J Melton | Mayo Clin Proc | 1996 | 8594285 | No |
2410 | 1353 | 1353.0 | 0.0 | 0.0 | Notes on continuous stochastic phenomena. | P A P Moran | Biometrika | 1950 | 15420245 | Yes |
2411 | 2705 | 1352.5 | 58.93 | 29.5 | NMR View: A computer program for the visualization and analysis of NMR data. | B A Johnson, R A Blevins | J Biomol NMR | 1994 | 22911360 | Yes |
2412 | 4056 | 1352.0 | 35.93 | 12.0 | Cytochemistry and electron microscopy. The preservation of cellular ultrastructure and enzymatic activity by aldehyde fixation. | D D Sabatini, K Bensch, R J Barrnett | J Cell Biol | 1963 | 13975866 | Yes |
2413 | 2703 | 1351.5 | 67.5 | 33.8 | The neural basis of human error processing: reinforcement learning, dopamine, and the error-related negativity. | Clay B Holroyd, Michael G H Coles | Psychol Rev | 2002 | 12374324 | Yes |
2414 | 1351 | 1351.0 | 41.15 | 41.1 | Neurotransmitters and neuromodulators in the basal ganglia. | A M Graybiel | Trends Neurosci | 1990 | 1695398 | No |
2415 | 8106 | 1351.0 | 203.13 | 33.9 | A default mode of brain function. | M E Raichle, A M MacLeod, A Z Snyder, W J Powers, D A Gusnard, G L Shulman | Proc Natl Acad Sci U S A | 2001 | 11209064 | Yes |
2416 | 2701 | 1350.5 | 125.02 | 62.5 | Glutathione peroxidase activity in selenium-deficient rat liver. | R A Lawrence, R F Burk | Biochem Biophys Res Commun | 1976 | 971321 | Yes |
2417 | 5400 | 1350.0 | 127.55 | 31.9 | The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling. | Konstantin Arnold, Lorenza Bordoli, Jürgen Kopp, Torsten Schwede | Bioinformatics | 2006 | 16301204 | Yes |
2418 | 1350 | 1350.0 | 0.0 | 0.0 | An approximate distribution of estimates of variance components. | F E Satterthwaite | Biometrics | 1946 | 20287815 | Yes |
2419 | 2699 | 1349.5 | 61.15 | 30.6 | Disruption of epithelial cell-matrix interactions induces apoptosis. | S M Frisch, H Francis | J Cell Biol | 1994 | 8106557 | Yes |
2420 | 1349 | 1349.0 | 42.36 | 42.4 | Glutathione metabolism and its selective modification. | A Meister | J Biol Chem | 1988 | 3053703 | No |
2421 | 1349 | 1349.0 | 36.32 | 36.3 | Atopic dermatitis. | Thomas Bieber | N Engl J Med | 2008 | 18385500 | Yes |
2422 | 5394 | 1348.5 | 124.55 | 31.1 | Quantitative monitoring of gene expression patterns with a complementary DNA microarray. | M Schena, D Shalon, R W Davis, P O Brown | Science | 1995 | 7569999 | Yes |
2423 | 1348 | 1348.0 | 35.58 | 35.6 | Seminars in medicine of the Beth Israel Hospital, Boston. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies. | S L Friedman | N Engl J Med | 1993 | 8502273 | No |
2424 | 4043 | 1347.7 | 104.2 | 34.7 | Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. | Robert D Schreiber, Lloyd J Old, Mark J Smyth | Science | 2011 | 21436444 | No |
2425 | 1347 | 1347.0 | 42.11 | 42.1 | Renin-angiotensin system: biochemistry and mechanisms of action. | M J Peach | Physiol Rev | 1977 | 191856 | No |
2426 | 1347 | 1347.0 | 28.11 | 28.1 | Stereological principles for morphometry in electron microscopic cytology. | E R Weibel | Int Rev Cytol | 1969 | 4899604 | No |
2427 | 1347 | 1347.0 | 140.18 | 140.2 | A Review of Coronavirus Disease-2019 (COVID-19). | Tanu Singhal | Indian J Pediatr | 2020 | 32166607 | No |
2428 | 2693 | 1346.5 | 64.92 | 32.5 | Regulation mechanisms and signaling pathways of autophagy. | Congcong He, Daniel J Klionsky | Annu Rev Genet | 2009 | 19653858 | No |
2429 | 2692 | 1346.0 | 61.6 | 30.8 | The RXR heterodimers and orphan receptors. | D J Mangelsdorf, R M Evans | Cell | 1995 | 8521508 | No |
2430 | 1346 | 1346.0 | 33.72 | 33.7 | A molecular view of microbial diversity and the biosphere. | N R Pace | Science | 1997 | 9115194 | No |
2431 | 1346 | 1346.0 | 28.49 | 28.5 | HIF-1: mediator of physiological and pathophysiological responses to hypoxia. | G L Semenza | J Appl Physiol (1985) | 2000 | 10749844 | No |
2432 | 2692 | 1346.0 | 75.57 | 37.8 | Epidemiology of invasive candidiasis: a persistent public health problem. | M A Pfaller, D J Diekema | Clin Microbiol Rev | 2007 | 17223626 | No |
2433 | 2691 | 1345.5 | 65.84 | 32.9 | The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. | Daniel J Drucker, Michael A Nauck | Lancet | 2006 | 17098089 | No |
2434 | 1345 | 1345.0 | 26.05 | 26.1 | Chromosomal translocations in human cancer. | T H Rabbitts | Nature | 1994 | 7969446 | No |
2435 | 2688 | 1344.0 | 90.67 | 45.3 | Plasma-high-density-lipoprotein concentration and development of ischaemic heart-disease. | G J Miller, N E Miller | Lancet | 1975 | 46338 | Yes |
2436 | 1344 | 1344.0 | 45.19 | 45.2 | Functional organization of central pathways regulating the cardiovascular system. | R A Dampney | Physiol Rev | 1994 | 8171117 | No |
2437 | 4032 | 1344.0 | 115.6 | 38.5 | A rapid bootstrap algorithm for the RAxML Web servers. | Alexandros Stamatakis, Paul Hoover, Jacques Rougemont | Syst Biol | 2008 | 18853362 | Yes |
2438 | 2686 | 1343.0 | 61.54 | 30.8 | Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma. | G Blobel, B Dobberstein | J Cell Biol | 1975 | 811671 | Yes |
2439 | 1343 | 1343.0 | 39.07 | 39.1 | Osteoblast adhesion on biomaterials. | K Anselme | Biomaterials | 2000 | 10711964 | No |
2440 | 8055 | 1342.5 | 239.43 | 39.9 | The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. | Erik von Elm, Douglas G Altman, Matthias Egger, Stuart J Pocock, Peter C Gøtzsche, Jan P Vandenbroucke | Lancet | 2007 | 18064739 | Yes |
2441 | 1342 | 1342.0 | 33.24 | 33.2 | The biologic clock: the mitochondria? | D Harman | J Am Geriatr Soc | 1972 | 5016631 | Yes |
2442 | 1342 | 1342.0 | 42.22 | 42.2 | The phenomenon of the acute phase response. | I Kushner | Ann N Y Acad Sci | 1982 | 7046585 | No |
2443 | 2683 | 1341.5 | 75.42 | 37.7 | The OPLS [optimized potentials for liquid simulations] potential functions for proteins, energy minimizations for crystals of cyclic peptides and crambin. | W L Jorgensen, J Tirado-Rives | J Am Chem Soc | 1988 | 27557051 | Yes |
2444 | 2682 | 1341.0 | 78.89 | 39.4 | A cognitive model of posttraumatic stress disorder. | A Ehlers, D M Clark | Behav Res Ther | 2000 | 10761279 | No |
2445 | 1341 | 1341.0 | 37.71 | 37.7 | Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles. | Felix Kratz | J Control Release | 2008 | 18582981 | No |
2446 | 1340 | 1340.0 | 24.23 | 24.2 | c-Myc target genes involved in cell growth, apoptosis, and metabolism. | C V Dang | Mol Cell Biol | 1999 | 9858526 | No |
2447 | 1340 | 1340.0 | 27.38 | 27.4 | The many faces of macrophage activation. | David M Mosser | J Leukoc Biol | 2003 | 12554797 | No |
2448 | 1340 | 1340.0 | 0.0 | 0.0 | The critical incident technique. | J C Flanagan | Psychol Bull | 1954 | 13177800 | Yes |
2449 | 1340 | 1340.0 | 43.2 | 43.2 | The amazing osteocyte. | Lynda F Bonewald | J Bone Miner Res | 2011 | 21254230 | No |
2450 | 1339 | 1339.0 | 47.89 | 47.9 | Letter: Grading of angina pectoris. | L Campeau | Circulation | 1976 | 947585 | Yes |
2451 | 1339 | 1339.0 | 35.61 | 35.6 | Fibronectin and its receptors. | E Ruoslahti | Annu Rev Biochem | 1988 | 2972252 | No |
2452 | 9373 | 1339.0 | 380.38 | 54.3 | Development and validation of a geriatric depression screening scale: a preliminary report. | J A Yesavage, T L Brink, T L Rose, O Lum, V Huang, M Adey, V O Leirer | J Psychiatr Res | 1982 | 7183759 | Yes |
2453 | 1339 | 1339.0 | 50.6 | 50.6 | Translating social ecological theory into guidelines for community health promotion. | D Stokols | Am J Health Promot | 1996 | 10159709 | No |
2454 | 1339 | 1339.0 | 0.0 | 0.0 | A simple ultraviolet spectrophotometric method for the determination of protein. | W J Waddell | J Lab Clin Med | 1956 | 13346201 | Yes |
2455 | 1339 | 1339.0 | 12.67 | 12.7 | Cellular resistance to infection. | G B Mackaness | J Exp Med | 1962 | 14467923 | Yes |
2456 | 1339 | 1339.0 | 25.16 | 25.2 | A modified procedure for lead staining of thin sections. | G Millonig | J Biophys Biochem Cytol | 1961 | 14474176 | Yes |
2457 | 2676 | 1338.0 | 93.45 | 46.7 | Total energy intake: implications for epidemiologic analyses. | W Willett, M J Stampfer | Am J Epidemiol | 1986 | 3521261 | No |
2458 | 1338 | 1338.0 | 47.24 | 47.2 | Neuropeptide Y: complete amino acid sequence of the brain peptide. | K Tatemoto | Proc Natl Acad Sci U S A | 1982 | 6957876 | Yes |
2459 | 1338 | 1338.0 | 29.25 | 29.2 | Physiological concentrations of purines and pyrimidines. | T W Traut | Mol Cell Biochem | 1994 | 7877593 | No |
2460 | 1338 | 1338.0 | 41.94 | 41.9 | Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data. | Thomas Heberer | Toxicol Lett | 2002 | 11988354 | Yes |
2461 | 1337 | 1337.0 | 34.97 | 35.0 | The molten globule state as a clue for understanding the folding and cooperativity of globular-protein structure. | K Kuwajima | Proteins | 1989 | 2695928 | No |
2462 | 2673 | 1336.5 | 77.44 | 38.7 | Evidence For The Existence Of Monoamine-Containing Neurons In The Central Nervous System. I. Demonstration Of Monoamines In The Cell Bodies Of Brain Stem Neurons. | A Dahlstroem, K Fuxe | Acta Physiol Scand Suppl | 1964 | 14229500 | Yes |
2463 | 1336 | 1336.0 | 28.5 | 28.5 | The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. | G B Morin | Cell | 1989 | 2805070 | Yes |
2464 | 2672 | 1336.0 | 59.75 | 29.9 | A comparison of bayesian methods for haplotype reconstruction from population genotype data. | Matthew Stephens, Peter Donnelly | Am J Hum Genet | 2003 | 14574645 | Yes |
2465 | 1336 | 1336.0 | 23.04 | 23.0 | Protein modification by SUMO. | Erica S Johnson | Annu Rev Biochem | 2004 | 15189146 | No |
2466 | 1336 | 1336.0 | 29.35 | 29.4 | Transcriptional control of adipocyte formation. | Stephen R Farmer | Cell Metab | 2006 | 17011499 | No |
2467 | 1336 | 1336.0 | 38.2 | 38.2 | Cytokinesis-block micronucleus cytome assay. | Michael Fenech | Nat Protoc | 2007 | 17546000 | Yes |
2468 | 1334 | 1334.0 | 28.67 | 28.7 | Codon usage and tRNA content in unicellular and multicellular organisms. | T Ikemura | Mol Biol Evol | 1985 | 3916708 | No |
2469 | 1334 | 1334.0 | 29.63 | 29.6 | Physiological and molecular basis of thyroid hormone action. | P M Yen | Physiol Rev | 2001 | 11427693 | No |
2470 | 2668 | 1334.0 | 54.28 | 27.1 | Regulated portals of entry into the cell. | Sean D Conner, Sandra L Schmid | Nature | 2003 | 12621426 | No |
2471 | 2668 | 1334.0 | 87.24 | 43.6 | Origins and evolution of antibiotic resistance. | Julian Davies, Dorothy Davies | Microbiol Mol Biol Rev | 2010 | 20805405 | No |
2472 | 2667 | 1333.5 | 74.82 | 37.4 | Further improvements in the plaque technique for detecting single antibody-forming cells. | A J Cunningham, A Szenberg | Immunology | 1968 | 5653817 | Yes |
2473 | 1333 | 1333.0 | 25.58 | 25.6 | microRNAs: tiny regulators with great potential. | V Ambros | Cell | 2001 | 11779458 | No |
2474 | 1333 | 1333.0 | 35.83 | 35.8 | Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects. | E B Hunziker | Osteoarthritis Cartilage | 2002 | 12056848 | No |
2475 | 1332 | 1332.0 | 20.72 | 20.7 | A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon. | A M Olovnikov | J Theor Biol | 1973 | 4754905 | Yes |
2476 | 1330 | 1330.0 | 34.64 | 34.6 | The aryl hydrocarbon receptor complex. | O Hankinson | Annu Rev Pharmacol Toxicol | 1995 | 7598497 | No |
2477 | 1330 | 1330.0 | 39.34 | 39.3 | Circuitry and functional aspects of the insular lobe in primates including humans. | J R Augustine | Brain Res Brain Res Rev | 1996 | 8957561 | No |
2478 | 1330 | 1330.0 | 41.92 | 41.9 | Electrocatalyst approaches and challenges for automotive fuel cells. | Mark K Debe | Nature | 2012 | 22678278 | Yes |
2479 | 5315 | 1328.8 | 130.69 | 32.7 | Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. | D W Cleveland, S G Fischer, M W Kirschner, U K Laemmli | J Biol Chem | 1977 | 320200 | Yes |
2480 | 2657 | 1328.5 | 82.61 | 41.3 | CTFFIND4: Fast and accurate defocus estimation from electron micrographs. | Alexis Rohou, Nikolaus Grigorieff | J Struct Biol | 2015 | 26278980 | Yes |
2481 | 3982 | 1327.3 | 99.65 | 33.2 | LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions. | A C Wallace, R A Laskowski, J M Thornton | Protein Eng | 1995 | 7630882 | Yes |
2482 | 1327 | 1327.0 | 33.69 | 33.7 | Thioredoxin and glutaredoxin systems. | A Holmgren | J Biol Chem | 1989 | 2668278 | No |
2483 | 2654 | 1327.0 | 60.39 | 30.2 | Integrins and signal transduction pathways: the road taken. | E A Clark, J S Brugge | Science | 1995 | 7716514 | No |
2484 | 6630 | 1326.0 | 181.94 | 36.4 | Transection of the oesophagus for bleeding oesophageal varices. | R N Pugh, I M Murray-Lyon, J L Dawson, M C Pietroni, R Williams | Br J Surg | 1973 | 4541913 | Yes |
2485 | 1326 | 1326.0 | 25.58 | 25.6 | Mechanisms of caspase activation and inhibition during apoptosis. | Yigong Shi | Mol Cell | 2002 | 11931755 | No |
2486 | 1326 | 1326.0 | 32.86 | 32.9 | N-heterocyclic carbenes: a new concept in organometallic catalysis. | Wolfgang A Herrmann | Angew Chem Int Ed Engl | 2002 | 19750753 | Yes |
2487 | 2651 | 1325.5 | 67.18 | 33.6 | Therapeutic potential of resveratrol: the in vivo evidence. | Joseph A Baur, David A Sinclair | Nat Rev Drug Discov | 2006 | 16732220 | No |
2488 | 2650 | 1325.0 | 72.48 | 36.2 | A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival. | B G Durie, S E Salmon | Cancer | 1975 | 1182674 | Yes |
2489 | 2650 | 1325.0 | 54.43 | 27.2 | Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter. | P J Southern, P Berg | J Mol Appl Genet | 1982 | 6286831 | Yes |
2490 | 1325 | 1325.0 | 31.75 | 31.8 | Apoptosis in cancer therapy: crossing the threshold. | D E Fisher | Cell | 1994 | 8069905 | No |
2491 | 1325 | 1325.0 | 29.93 | 29.9 | Functions of the neurotrophins during nervous system development: what the knockouts are teaching us. | W D Snider | Cell | 1994 | 8205613 | No |
2492 | 3975 | 1325.0 | 96.92 | 32.3 | Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm. | Y Zhang, M Brady, S Smith | IEEE Trans Med Imaging | 2001 | 11293691 | Yes |
2493 | 3973 | 1324.3 | 209.45 | 69.8 | Shedding light on the cell biology of extracellular vesicles. | Guillaume van Niel, Gisela D'Angelo, Graça Raposo | Nat Rev Mol Cell Biol | 2018 | 29339798 | No |
2494 | 1324 | 1324.0 | 23.08 | 23.1 | Regulatory T cells: key controllers of immunologic self-tolerance. | S Sakaguchi | Cell | 2000 | 10850488 | No |
2495 | 1324 | 1324.0 | 23.4 | 23.4 | SUMO: a history of modification. | Ronald T Hay | Mol Cell | 2005 | 15808504 | No |
2496 | 1324 | 1324.0 | 33.99 | 34.0 | Microbial influences in inflammatory bowel diseases. | R Balfour Sartor | Gastroenterology | 2008 | 18242222 | No |
2497 | 1323 | 1323.0 | 50.93 | 50.9 | Free-radical mechanisms in tissue injury. | T F Slater | Biochem J | 1984 | 6383353 | No |
2498 | 1323 | 1323.0 | 63.43 | 63.4 | The clinical application of the biopsychosocial model. | G L Engel | Am J Psychiatry | 1980 | 7369396 | Yes |
2499 | 1323 | 1323.0 | 28.08 | 28.1 | The enzymes, regulation, and genetics of bile acid synthesis. | David W Russell | Annu Rev Biochem | 2003 | 12543708 | No |
2500 | 1323 | 1323.0 | 31.42 | 31.4 | Recent advances in neuroblastoma. | John M Maris | N Engl J Med | 2010 | 20558371 | No |
2501 | 1322 | 1322.0 | 24.61 | 24.6 | Antigen-specific interaction between T and B cells. | A Lanzavecchia | Nature | 1985 | 3157869 | Yes |
2502 | 1322 | 1322.0 | 0.0 | 0.0 | On the psychophysical law. | S S Stevens | Psychol Rev | 1957 | 13441853 | Yes |
2503 | 3965 | 1321.7 | 102.37 | 34.1 | Cognitive and emotional influences in anterior cingulate cortex. | G Bush, P Luu, M I Posner | Trends Cogn Sci | 2000 | 10827444 | Yes |
2504 | 5284 | 1321.0 | 116.88 | 29.2 | Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. | Eugenia E Calle, Carmen Rodriguez, Kimberly Walker-Thurmond, Michael J Thun | N Engl J Med | 2003 | 12711737 | Yes |
2505 | 3962 | 1320.7 | 97.35 | 32.4 | The p53 tumour suppressor gene. | A J Levine, J Momand, C A Finlay | Nature | 1991 | 2046748 | No |
2506 | 3962 | 1320.7 | 90.3 | 30.1 | Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? | Witold Filipowicz, Suvendra N Bhattacharyya, Nahum Sonenberg | Nat Rev Genet | 2008 | 18197166 | No |
2507 | 2641 | 1320.5 | 55.48 | 27.7 | Liver regeneration. | G K Michalopoulos, M C DeFrances | Science | 1997 | 9082986 | No |
2508 | 2641 | 1320.5 | 64.21 | 32.1 | Microglia: active sensor and versatile effector cells in the normal and pathologic brain. | Uwe-Karsten Hanisch, Helmut Kettenmann | Nat Neurosci | 2007 | 17965659 | No |
2509 | 1320 | 1320.0 | 29.06 | 29.1 | Measuring information transfer | T Schreiber | Phys Rev Lett | 2000 | 10991308 | Yes |
2510 | 3958 | 1319.3 | 106.86 | 35.6 | Nitric oxide and peroxynitrite in health and disease. | Pál Pacher, Joseph S Beckman, Lucas Liaudet | Physiol Rev | 2007 | 17237348 | No |
2511 | 1319 | 1319.0 | 37.68 | 37.7 | Stimulus-secretion coupling: the concept and clues from chromaffin and other cells. | W W Douglas | Br J Pharmacol | 1968 | 4882190 | No |
2512 | 1319 | 1319.0 | 65.22 | 65.2 | Displaced proximal humeral fractures. I. Classification and evaluation. | C S Neer | J Bone Joint Surg Am | 1970 | 5455339 | Yes |
2513 | 1319 | 1319.0 | 23.04 | 23.0 | Clonal selection and learning in the antibody system. | K Rajewsky | Nature | 1996 | 8657279 | No |
2514 | 2638 | 1319.0 | 90.66 | 45.3 | Functional interactions between the gut microbiota and host metabolism. | Valentina Tremaroli, Fredrik Bäckhed | Nature | 2012 | 22972297 | No |
2515 | 2637 | 1318.5 | 96.72 | 48.4 | Enzyme-linked immunosorbent assay, Elisa. 3. Quantitation of specific antibodies by enzyme-labeled anti-immunoglobulin in antigen-coated tubes. | E Engvall, P Perlmann | J Immunol | 1972 | 4113792 | Yes |
2516 | 2637 | 1318.5 | 48.59 | 24.3 | Immunization of dissociated spleen cell cultures from normal mice. | R I Mishell, R W Dutton | J Exp Med | 1967 | 6034749 | Yes |
2517 | 1318 | 1318.0 | 48.1 | 48.1 | The life and times of the Enterococcus. | B E Murray | Clin Microbiol Rev | 1990 | 2404568 | No |
2518 | 3954 | 1318.0 | 83.96 | 28.0 | A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. | R Medzhitov, P Preston-Hurlburt, C A Janeway | Nature | 1997 | 9237759 | Yes |
2519 | 1318 | 1318.0 | 35.37 | 35.4 | Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. | Arnold I Caplan | J Cell Physiol | 2007 | 17620285 | No |
2520 | 1317 | 1317.0 | 42.65 | 42.6 | An application of prefrontal cortex function theory to cognitive aging. | R L West | Psychol Bull | 1996 | 8831298 | No |
2521 | 1316 | 1316.0 | 36.96 | 37.0 | The matrix-degrading metalloproteinases. | L M Matrisian | Bioessays | 1992 | 1445287 | No |
2522 | 1316 | 1316.0 | 39.08 | 39.1 | Classification of chronic viral hepatitis: a need for reassessment. | P J Scheuer | J Hepatol | 1991 | 1808228 | No |
2523 | 1316 | 1316.0 | 17.06 | 17.1 | Disconnexion syndromes in animals and man. I. | N Geschwind | Brain | 1965 | 5318481 | No |
2524 | 1316 | 1316.0 | 33.3 | 33.3 | Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders. | R M Sapolsky | Arch Gen Psychiatry | 2000 | 11015810 | No |
2525 | 1316 | 1316.0 | 0.0 | 0.0 | A quantitative immunochemical measure of the primary interaction between I BSA and antibody. | R S Farr | J Infect Dis | 1958 | 13611294 | Yes |
2526 | 1316 | 1316.0 | 51.27 | 51.3 | What is self-rated health and why does it predict mortality? Towards a unified conceptual model. | Marja Jylhä | Soc Sci Med | 2009 | 19520474 | Yes |
2527 | 1315 | 1315.0 | 34.63 | 34.6 | Phylogenies from molecular sequences: inference and reliability. | J Felsenstein | Annu Rev Genet | 1988 | 3071258 | No |
2528 | 1315 | 1315.0 | 45.11 | 45.1 | Carnitine--metabolism and functions. | J Bremer | Physiol Rev | 1983 | 6361812 | No |
2529 | 1315 | 1315.0 | 28.52 | 28.5 | Mechanisms of foxp3+ T regulatory cell-mediated suppression. | Ethan M Shevach | Immunity | 2009 | 19464986 | No |
2530 | 2628 | 1314.0 | 100.62 | 50.3 | Malondialdehyde determination as index of lipid peroxidation. | H H Draper, M Hadley | Methods Enzymol | 1990 | 2233309 | Yes |
2531 | 2628 | 1314.0 | 41.45 | 20.7 | Functions of lysosomes. | C De Duve, R Wattiaux | Annu Rev Physiol | 1966 | 5322983 | No |
2532 | 1314 | 1314.0 | 27.66 | 27.7 | Double identity for proteins of the Bcl-2 family. | J C Reed | Nature | 1997 | 9194558 | No |
2533 | 1314 | 1314.0 | 28.06 | 28.1 | Prediction of protein cellular attributes using pseudo-amino acid composition. | K C Chou | Proteins | 2001 | 11288174 | Yes |
2534 | 1314 | 1314.0 | 58.66 | 58.7 | Machine Learning in Medicine. | Rahul C Deo | Circulation | 2015 | 26572668 | No |
2535 | 2626 | 1313.0 | 48.87 | 24.4 | New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. | R D Gietz, A Sugino | Gene | 1988 | 3073106 | Yes |
2536 | 2626 | 1313.0 | 58.21 | 29.1 | Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. | Jane E Visvader, Geoffrey J Lindeman | Nat Rev Cancer | 2008 | 18784658 | No |
2537 | 2625 | 1312.5 | 46.38 | 23.2 | Rab proteins as membrane organizers. | M Zerial, H McBride | Nat Rev Mol Cell Biol | 2001 | 11252952 | No |
2538 | 5249 | 1312.2 | 132.08 | 33.0 | Universal sample preparation method for proteome analysis. | Jacek R Wiśniewski, Alexandre Zougman, Nagarjuna Nagaraj, Matthias Mann | Nat Methods | 2009 | 19377485 | Yes |
2539 | 1312 | 1312.0 | 26.98 | 27.0 | Solving structures of protein complexes by molecular replacement with Phaser. | Airlie J McCoy | Acta Crystallogr D Biol Crystallogr | 2007 | 17164524 | Yes |
2540 | 1312 | 1312.0 | 37.63 | 37.6 | BEDTools: The Swiss-Army Tool for Genome Feature Analysis. | Aaron R Quinlan | Curr Protoc Bioinformatics | 2014 | 25199790 | Yes |
2541 | 5244 | 1311.0 | 123.81 | 31.0 | Improved prediction of signal peptides: SignalP 3.0. | Jannick Dyrløv Bendtsen, Henrik Nielsen, Gunnar von Heijne, Søren Brunak | J Mol Biol | 2004 | 15223320 | Yes |
2542 | 1310 | 1310.0 | 32.82 | 32.8 | Comparative physiology of salt and water stress. | R. Munns | Plant Cell Environ | 2002 | 11841667 | Yes |
2543 | 2620 | 1310.0 | 61.3 | 30.6 | Microenvironmental regulation of metastasis. | Johanna A Joyce, Jeffrey W Pollard | Nat Rev Cancer | 2009 | 19279573 | No |
2544 | 1310 | 1310.0 | 0.0 | 0.0 | Analyzer for accurate estimation of respiratory gases in one-half cubic centimeter samples. | P F Scholander | J Biol Chem | 1947 | 20281644 | Yes |
2545 | 1310 | 1310.0 | 118.66 | 118.7 | Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults. | Jonas F Ludvigsson | Acta Paediatr | 2020 | 32202343 | Yes |
2546 | 2619 | 1309.5 | 59.33 | 29.7 | Supercoil sequencing: a fast and simple method for sequencing plasmid DNA. | E Y Chen, P H Seeburg | DNA | 1985 | 3996185 | Yes |
2547 | 1309 | 1309.0 | 33.88 | 33.9 | Supported membranes: scientific and practical applications. | E Sackmann | Science | 1996 | 8539599 | No |
2548 | 1309 | 1309.0 | 32.55 | 32.5 | Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. | G L Semenza | Oncogene | 2010 | 19946328 | No |
2549 | 3925 | 1308.3 | 139.56 | 46.5 | A new method for off-line removal of ocular artifact. | G Gratton, M G Coles, E Donchin | Electroencephalogr Clin Neurophysiol | 1983 | 6187540 | Yes |
2550 | 2616 | 1308.0 | 117.06 | 58.5 | Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty. | J M Tanner, R H Whitehouse | Arch Dis Child | 1976 | 952550 | Yes |
2551 | 2616 | 1308.0 | 58.06 | 29.0 | ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking. | Matthew D Wilkerson, D Neil Hayes | Bioinformatics | 2010 | 20427518 | Yes |
2552 | 2616 | 1308.0 | 71.35 | 35.7 | Tumor metastasis: molecular insights and evolving paradigms. | Scott Valastyan, Robert A Weinberg | Cell | 2011 | 22000009 | No |
2553 | 1307 | 1307.0 | 29.92 | 29.9 | Oxidative stress in neurodegeneration: cause or consequence? | Julie K Andersen | Nat Med | 2004 | 15298006 | No |
2554 | 1307 | 1307.0 | 27.52 | 27.5 | Human natural killer cells. | Michael A Caligiuri | Blood | 2008 | 18650461 | No |
2555 | 3920 | 1306.7 | 93.24 | 31.1 | Functional porous coordination polymers. | Susumu Kitagawa, Ryo Kitaura, Shin-ichiro Noro | Angew Chem Int Ed Engl | 2004 | 15114565 | Yes |
2556 | 1306 | 1306.0 | 54.2 | 54.2 | Error in medicine. | L L Leape | JAMA | 1994 | 7503827 | Yes |
2557 | 1306 | 1306.0 | 23.66 | 23.7 | CD95's deadly mission in the immune system. | P H Krammer | Nature | 2000 | 11048730 | No |
2558 | 1306 | 1306.0 | 0.0 | 0.0 | The anterior approach for removal of ruptured cervical disks. | R B Cloward | J Neurosurg | 1958 | 13599052 | Yes |
2559 | 1305 | 1305.0 | 69.88 | 69.9 | Psychosocial resilience and protective mechanisms. | Michael Rutter | Am J Orthopsychiatry | 1987 | 3303954 | No |
2560 | 1305 | 1305.0 | 39.0 | 39.0 | Gadolinium--a specific trigger for the development of nephrogenic fibrosing dermopathy and nephrogenic systemic fibrosis? | Thomas Grobner | Nephrol Dial Transplant | 2006 | 16431890 | Yes |
2561 | 1304 | 1304.0 | 38.07 | 38.1 | Qinghaosu (artemisinin): an antimalarial drug from China. | D L Klayman | Science | 1985 | 3887571 | No |
2562 | 2608 | 1304.0 | 40.28 | 20.1 | The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites. | J Shine, L Dalgarno | Proc Natl Acad Sci U S A | 1974 | 4598299 | Yes |
2563 | 1304 | 1304.0 | 35.28 | 35.3 | Polycystic ovary syndrome. | David A Ehrmann | N Engl J Med | 2005 | 15788499 | No |
2564 | 1304 | 1304.0 | 44.21 | 44.2 | AmpC beta-lactamases. | George A Jacoby | Clin Microbiol Rev | 2009 | 19136439 | No |
2565 | 6518 | 1303.6 | 250.89 | 50.2 | Fsl. | Mark Jenkinson, Christian F Beckmann, Timothy E J Behrens, Mark W Woolrich, Stephen M Smith | Neuroimage | 2012 | 21979382 | No |
2566 | 2607 | 1303.5 | 106.02 | 53.0 | A typology of reviews: an analysis of 14 review types and associated methodologies. | Maria J Grant, Andrew Booth | Health Info Libr J | 2009 | 19490148 | No |
2567 | 2607 | 1303.5 | 63.33 | 31.7 | Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. | Subhra K Biswas, Alberto Mantovani | Nat Immunol | 2010 | 20856220 | No |
2568 | 1303 | 1303.0 | 29.54 | 29.5 | Metastatic bone disease: clinical features, pathophysiology and treatment strategies. | R E Coleman | Cancer Treat Rev | 2001 | 11417967 | No |
2569 | 1303 | 1303.0 | 30.94 | 30.9 | Non-Smad pathways in TGF-beta signaling. | Ying E Zhang | Cell Res | 2009 | 19114990 | No |
2570 | 2605 | 1302.5 | 56.17 | 28.1 | Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information. | M Zuker, P Stiegler | Nucleic Acids Res | 1981 | 6163133 | Yes |
2571 | 3907 | 1302.3 | 146.61 | 48.9 | Complex heatmaps reveal patterns and correlations in multidimensional genomic data. | Zuguang Gu, Roland Eils, Matthias Schlesner | Bioinformatics | 2016 | 27207943 | Yes |
2572 | 1302 | 1302.0 | 31.22 | 31.2 | Receptors for epidermal growth factor and other polypeptide mitogens. | G Carpenter | Annu Rev Biochem | 1987 | 3039909 | No |
2573 | 1302 | 1302.0 | 21.65 | 21.6 | Extraordinary sex ratios. A sex-ratio theory for sex linkage and inbreeding has new implications in cytogenetics and entomology. | W D Hamilton | Science | 1967 | 6021675 | Yes |
2574 | 2603 | 1301.5 | 43.61 | 21.8 | Genetic transformation of Drosophila with transposable element vectors. | G M Rubin, A C Spradling | Science | 1982 | 6289436 | Yes |
2575 | 2603 | 1301.5 | 87.02 | 43.5 | Social conditions as fundamental causes of disease. | B G Link, J Phelan | J Health Soc Behav | 1995 | 7560851 | No |
2576 | 1301 | 1301.0 | 44.53 | 44.5 | The theoretical bases of indirect calorimetry: a review. | E Ferrannini | Metabolism | 1988 | 3278194 | No |
2577 | 3903 | 1301.0 | 80.29 | 26.8 | Calcium signalling: dynamics, homeostasis and remodelling. | Michael J Berridge, Martin D Bootman, H Llewelyn Roderick | Nat Rev Mol Cell Biol | 2003 | 12838335 | No |
2578 | 1301 | 1301.0 | 34.2 | 34.2 | The sympathetic control of blood pressure. | Patrice G Guyenet | Nat Rev Neurosci | 2006 | 16760914 | No |
2579 | 2602 | 1301.0 | 95.0 | 47.5 | Role of the microbiota in immunity and inflammation. | Yasmine Belkaid, Timothy W Hand | Cell | 2014 | 24679531 | No |
2580 | 2601 | 1300.5 | 82.65 | 41.3 | Epidermal growth factor. | G Carpenter, S Cohen | Annu Rev Biochem | 1979 | 382984 | No |
2581 | 3900 | 1300.0 | 85.97 | 28.7 | Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. | Axel Nimmerjahn, Frank Kirchhoff, Fritjof Helmchen | Science | 2005 | 15831717 | Yes |
2582 | 3898 | 1299.3 | 90.55 | 30.2 | Tissue cells feel and respond to the stiffness of their substrate. | Dennis E Discher, Paul Janmey, Yu-Li Wang | Science | 2005 | 16293750 | No |
2583 | 1298 | 1298.0 | 11.65 | 11.7 | Metabolic stability and epigenesis in randomly constructed genetic nets. | S A Kauffman | J Theor Biol | 1969 | 5803332 | Yes |
2584 | 2596 | 1298.0 | 66.88 | 33.4 | Apoptosis, oncosis, and necrosis. An overview of cell death. | G Majno, I Joris | Am J Pathol | 1995 | 7856735 | No |
2585 | 1298 | 1298.0 | 57.31 | 57.3 | 1,500 scientists lift the lid on reproducibility. | Monya Baker | Nature | 2016 | 27225100 | No |
2586 | 2596 | 1298.0 | 190.7 | 95.3 | ape 5.0: an environment for modern phylogenetics and evolutionary analyses in R. | Emmanuel Paradis, Klaus Schliep | Bioinformatics | 2019 | 30016406 | Yes |
2587 | 1297 | 1297.0 | 42.3 | 42.3 | Optimal foraging, the marginal value theorem. | E L Charnov | Theor Popul Biol | 1976 | 1273796 | Yes |
2588 | 1297 | 1297.0 | 34.49 | 34.5 | Sarcopenia: origins and clinical relevance. | I H Rosenberg | J Nutr | 1997 | 9164280 | No |
2589 | 7777 | 1296.2 | 197.02 | 32.8 | Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research. | Ana Conesa, Stefan Götz, Juan Miguel García-Gómez, Javier Terol, Manuel Talón, Montserrat Robles | Bioinformatics | 2005 | 16081474 | Yes |
2590 | 1296 | 1296.0 | 28.47 | 28.5 | Long-term potentiation and memory. | M A Lynch | Physiol Rev | 2004 | 14715912 | No |
2591 | 1296 | 1296.0 | 29.89 | 29.9 | The path to ubiquitous and low-cost organic electronic appliances on plastic. | Stephen R Forrest | Nature | 2004 | 15118718 | Yes |
2592 | 1295 | 1295.0 | 43.6 | 43.6 | Ruthenium red and violet. I. Chemistry, purification, methods of use for electron microscopy and mechanism of action. | J H Luft | Anat Rec | 1971 | 4108333 | Yes |
2593 | 1295 | 1295.0 | 60.1 | 60.1 | Oxidative stress: a concept in redox biology and medicine. | Helmut Sies | Redox Biol | 2015 | 25588755 | No |
2594 | 2589 | 1294.5 | 55.74 | 27.9 | Mitochondrial control of cell death. | G Kroemer, J C Reed | Nat Med | 2000 | 10802706 | No |
2595 | 3883 | 1294.3 | 99.47 | 33.2 | Atomic force microscope. | G Binnig, C F Quate, C Gerber | Phys Rev Lett | 1986 | 10033323 | Yes |
2596 | 1294 | 1294.0 | 0.0 | 0.0 | On the local reactions of the arterial wall to changes of internal pressure. | W M Bayliss | J Physiol | 1902 | 16992618 | Yes |
2597 | 1294 | 1294.0 | 0.0 | 0.0 | Limitations of the application of fourfold table analysis to hospital data. | J Berkson | Biometrics | 1946 | 21001024 | Yes |
2598 | 6467 | 1293.4 | 158.84 | 31.8 | Enzymatic determination of total serum cholesterol. | C C Allain, L S Poon, C S Chan, W Richmond, P C Fu | Clin Chem | 1974 | 4818200 | Yes |
2599 | 2586 | 1293.0 | 61.52 | 30.8 | Multipoint quantitative-trait linkage analysis in general pedigrees. | L Almasy, J Blangero | Am J Hum Genet | 1998 | 9545414 | Yes |
2600 | 1293 | 1293.0 | 30.16 | 30.2 | Pathways of oxidative damage. | James A Imlay | Annu Rev Microbiol | 2003 | 14527285 | No |
2601 | 5171 | 1292.8 | 103.66 | 25.9 | Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. | D D Sarbassov, David A Guertin, Siraj M Ali, David M Sabatini | Science | 2005 | 15718470 | Yes |
2602 | 2585 | 1292.5 | 37.77 | 18.9 | Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. | J E Sulston, H R Horvitz | Dev Biol | 1977 | 838129 | Yes |
2603 | 1292 | 1292.0 | 31.74 | 31.7 | Surrogate endpoints in clinical trials: definition and operational criteria. | R L Prentice | Stat Med | 1989 | 2727467 | Yes |
2604 | 2584 | 1292.0 | 82.72 | 41.4 | Tumor-associated macrophages: from mechanisms to therapy. | Roy Noy, Jeffrey W Pollard | Immunity | 2014 | 25035953 | No |
2605 | 2583 | 1291.5 | 58.91 | 29.5 | Cell cycle, CDKs and cancer: a changing paradigm. | Marcos Malumbres, Mariano Barbacid | Nat Rev Cancer | 2009 | 19238148 | No |
2606 | 2580 | 1290.0 | 75.07 | 37.5 | Prediction of the secondary structure of proteins from their amino acid sequence. | P Y Chou, G D Fasman | Adv Enzymol Relat Areas Mol Biol | 1978 | 364941 | No |
2607 | 1290 | 1290.0 | 29.52 | 29.5 | Oxyradicals and DNA damage. | L J Marnett | Carcinogenesis | 2000 | 10688856 | No |
2608 | 1290 | 1290.0 | 37.97 | 38.0 | Endometriosis. | Serdar E Bulun | N Engl J Med | 2009 | 19144942 | No |
2609 | 2579 | 1289.5 | 61.27 | 30.6 | Production of single-stranded plasmid DNA. | J Vieira, J Messing | Methods Enzymol | 1987 | 3323803 | Yes |
2610 | 1289 | 1289.0 | 29.73 | 29.7 | Tumour necrosis factor and cancer. | Frances Balkwill | Nat Rev Cancer | 2009 | 19343034 | No |
2611 | 3866 | 1288.7 | 101.06 | 33.7 | Bacterial biofilms: from the natural environment to infectious diseases. | Luanne Hall-Stoodley, J William Costerton, Paul Stoodley | Nat Rev Microbiol | 2004 | 15040259 | No |
2612 | 2577 | 1288.5 | 71.11 | 35.6 | What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience? | K C Berridge, T E Robinson | Brain Res Brain Res Rev | 1998 | 9858756 | No |
2613 | 1288 | 1288.0 | 30.42 | 30.4 | Lymphokine production by human T cells in disease states. | S Romagnani | Annu Rev Immunol | 1994 | 8011282 | No |
2614 | 6440 | 1288.0 | 121.6 | 24.3 | Crystal structure of the nucleosome core particle at 2.8 A resolution. | K Luger, A W Mäder, R K Richmond, D F Sargent, T J Richmond | Nature | 1997 | 9305837 | Yes |
2615 | 5150 | 1287.5 | 224.07 | 56.0 | Progressive statistics for studies in sports medicine and exercise science. | William G Hopkins, Stephen W Marshall, Alan M Batterham, Juri Hanin | Med Sci Sports Exerc | 2009 | 19092709 | No |
2616 | 1287 | 1287.0 | 34.42 | 34.4 | Isolation of leucocytes from human blood. Further observations. Methylcellulose, dextran, and ficoll as erythrocyteaggregating agents. | A Böyum | Scand J Clin Lab Invest Suppl | 1968 | 4179066 | Yes |
2617 | 1287 | 1287.0 | 39.34 | 39.3 | Chronic disease management: what will it take to improve care for chronic illness? | E H Wagner | Eff Clin Pract | 1998 | 10345255 | No |
2618 | 1287 | 1287.0 | 33.1 | 33.1 | Psychological and neural mechanisms of the affective dimension of pain. | D D Price | Science | 2000 | 10846154 | No |
2619 | 1287 | 1287.0 | 27.2 | 27.2 | The stem-cell niche as an entity of action. | David T Scadden | Nature | 2006 | 16810242 | No |
2620 | 3860 | 1286.7 | 90.86 | 30.3 | Evolution and functions of long noncoding RNAs. | Chris P Ponting, Peter L Oliver, Wolf Reik | Cell | 2009 | 19239885 | No |
2621 | 2573 | 1286.5 | 87.64 | 43.8 | Regulatory sequences involved in the promotion and termination of RNA transcription. | M Rosenberg, D Court | Annu Rev Genet | 1979 | 94251 | No |
2622 | 1286 | 1286.0 | 40.43 | 40.4 | Electrophoretic separation of plasma lipoproteins in agarose gel. | R P Noble | J Lipid Res | 1968 | 4176473 | Yes |
2623 | 1286 | 1286.0 | 59.32 | 59.3 | Cardiovascular and renal actions of dopamine: potential clinical applications. | L I Goldberg | Pharmacol Rev | 1972 | 4554480 | No |
2624 | 1286 | 1286.0 | 35.16 | 35.2 | The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions. | R G Gerrity | Am J Pathol | 1981 | 7234961 | Yes |
2625 | 1286 | 1286.0 | 29.08 | 29.1 | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. | Nigel Unwin | J Mol Biol | 2005 | 15701510 | Yes |
2626 | 2571 | 1285.5 | 81.92 | 41.0 | Oxidative mechanisms in the toxicity of metal ions. | S J Stohs, D Bagchi | Free Radic Biol Med | 1995 | 7744317 | No |
2627 | 2570 | 1285.0 | 65.31 | 32.7 | Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. | J A Ledbetter, L A Herzenberg | Immunol Rev | 1979 | 398327 | No |
2628 | 1285 | 1285.0 | 29.04 | 29.0 | Chemistry and biology of the immunophilins and their immunosuppressive ligands. | S L Schreiber | Science | 1991 | 1702904 | No |
2629 | 1285 | 1285.0 | 38.9 | 38.9 | Diversity and ubiquity of K channels. | B Rudy | Neuroscience | 1988 | 2457185 | No |
2630 | 1285 | 1285.0 | 30.67 | 30.7 | Papillomavirus infections--a major cause of human cancers. | H zur Hausen | Biochim Biophys Acta | 1996 | 8876633 | No |
2631 | 1285 | 1285.0 | 40.45 | 40.5 | Thermal properties of graphene and nanostructured carbon materials. | Alexander A Balandin | Nat Mater | 2011 | 21778997 | Yes |
2632 | 2569 | 1284.5 | 56.57 | 28.3 | Breaking the diffraction resolution limit by stimulated emission: stimulated-emission-depletion fluorescence microscopy. | S W Hell, J Wichmann | Opt Lett | 1994 | 19844443 | Yes |
2633 | 1284 | 1284.0 | 32.68 | 32.7 | Pain and emotion interactions in subregions of the cingulate gyrus. | Brent A Vogt | Nat Rev Neurosci | 2005 | 15995724 | No |
2634 | 2567 | 1283.5 | 158.7 | 79.3 | Facial nerve grading system. | J W House, D E Brackmann | Otolaryngol Head Neck Surg | 1985 | 3921901 | Yes |
2635 | 2567 | 1283.5 | 63.72 | 31.9 | Interneurons of the hippocampus. | T F Freund, G Buzsáki | Hippocampus | 1996 | 8915675 | No |
2636 | 2567 | 1283.5 | 61.48 | 30.7 | C-reactive protein: a critical update. | Mark B Pepys, Gideon M Hirschfield | J Clin Invest | 2003 | 12813013 | No |
2637 | 2564 | 1282.0 | 129.13 | 64.6 | A study of the natural history of back pain. Part I: development of a reliable and sensitive measure of disability in low-back pain. | M Roland, R Morris | Spine (Phila Pa 1976) | 1983 | 6222486 | Yes |
2638 | 2564 | 1282.0 | 46.71 | 23.4 | Live or let die: the cell's response to p53. | Karen H Vousden, Xin Lu | Nat Rev Cancer | 2002 | 12154352 | No |
2639 | 14102 | 1282.0 | 380.75 | 34.6 | The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. | Aram V Chobanian, George L Bakris, Henry R Black, William C Cushman, Lee A Green, Joseph L Izzo, Daniel W Jones, Barry J Materson, Suzanne Oparil, Jackson T Wright, Edward J Roccella | JAMA | 2003 | 12748199 | No |
2640 | 2564 | 1282.0 | 0.0 | 0.0 | Primary carcinoma of the liver: a study of 100 cases among 48,900 necropsies. | H A Edmondson, P E Steiner | Cancer | 1954 | 13160935 | Yes |
2641 | 1282 | 1282.0 | 31.7 | 31.7 | Overview of general physiologic features and functions of vitamin D. | Hector F DeLuca | Am J Clin Nutr | 2004 | 15585789 | No |
2642 | 1281 | 1281.0 | 39.45 | 39.5 | Somatostatin. | S Reichlin | N Engl J Med | 1983 | 6139753 | No |
2643 | 1281 | 1281.0 | 28.35 | 28.4 | Liver fibrosis -- from bench to bedside. | Scott L Friedman | J Hepatol | 2003 | 12591185 | No |
2644 | 1281 | 1281.0 | 23.96 | 24.0 | Mobile elements: drivers of genome evolution. | Haig H Kazazian | Science | 2004 | 15016989 | No |
2645 | 1281 | 1281.0 | 26.89 | 26.9 | Neuroligins and neurexins link synaptic function to cognitive disease. | Thomas C Südhof | Nature | 2008 | 18923512 | No |
2646 | 2561 | 1280.5 | 66.17 | 33.1 | Establishment and characterization of a human histiocytic lymphoma cell line (U-937). | C Sundström, K Nilsson | Int J Cancer | 1976 | 178611 | Yes |
2647 | 2561 | 1280.5 | 46.02 | 23.0 | DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. | Christopher J Bakkenist, Michael B Kastan | Nature | 2003 | 12556884 | Yes |
2648 | 2561 | 1280.5 | 55.02 | 27.5 | The pathophysiology of mitochondrial cell death. | Douglas R Green, Guido Kroemer | Science | 2004 | 15286356 | No |
2649 | 1280 | 1280.0 | 41.18 | 41.2 | How stigma interferes with mental health care. | Patrick Corrigan | Am Psychol | 2004 | 15491256 | Yes |
2650 | 3838 | 1279.3 | 86.76 | 28.9 | Photodynamic therapy for cancer. | Dennis E J G J Dolmans, Dai Fukumura, Rakesh K Jain | Nat Rev Cancer | 2003 | 12724736 | No |
2651 | 3838 | 1279.3 | 127.09 | 42.4 | Rehospitalizations among patients in the Medicare fee-for-service program. | Stephen F Jencks, Mark V Williams, Eric A Coleman | N Engl J Med | 2009 | 19339721 | Yes |
2652 | 1279 | 1279.0 | 46.67 | 46.7 | Substance P. | B Pernow | Pharmacol Rev | 1983 | 6196797 | No |
2653 | 1279 | 1279.0 | 28.49 | 28.5 | Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration. | T A Springer | Annu Rev Physiol | 1995 | 7778885 | No |
2654 | 1279 | 1279.0 | 0.0 | 0.0 | Agammaglobulinemia. | O C Bruton | Pediatrics | 1952 | 14929630 | Yes |
2655 | 1279 | 1279.0 | 54.92 | 54.9 | Rhythms for Cognition: Communication through Coherence. | Pascal Fries | Neuron | 2015 | 26447583 | No |
2656 | 8950 | 1278.6 | 253.51 | 36.2 | Cancer statistics, 2008. | Ahmedin Jemal, Rebecca Siegel, Elizabeth Ward, Yongping Hao, Jiaquan Xu, Taylor Murray, Michael J Thun | CA Cancer J Clin | 2008 | 18287387 | Yes |
2657 | 2557 | 1278.5 | 52.58 | 26.3 | The molecular biology of axon guidance. | M Tessier-Lavigne, C S Goodman | Science | 1996 | 8895455 | No |
2658 | 1278 | 1278.0 | 40.97 | 41.0 | Bee and wasp venoms. | E Habermann | Science | 1972 | 4113805 | No |
2659 | 1278 | 1278.0 | 79.94 | 79.9 | A comparison of canal preparations in straight and curved root canals. | S W Schneider | Oral Surg Oral Med Oral Pathol | 1971 | 5284110 | Yes |
2660 | 1278 | 1278.0 | 43.05 | 43.0 | Density matrix formulation for quantum renormalization groups. | S R White | Phys Rev Lett | 1992 | 10046608 | Yes |
2661 | 2555 | 1277.5 | 62.78 | 31.4 | The free radical theory of aging matures. | K B Beckman, B N Ames | Physiol Rev | 1998 | 9562038 | No |
2662 | 2555 | 1277.5 | 0.0 | 0.0 | Construct validity in psychological tests. | L J Cronbach, P E Meehl | Psychol Bull | 1955 | 13245896 | Yes |
2663 | 1277 | 1277.0 | 32.01 | 32.0 | The mitochondrial electron transport and oxidative phosphorylation system. | Y Hatefi | Annu Rev Biochem | 1985 | 2862839 | No |
2664 | 2554 | 1277.0 | 23.62 | 11.8 | Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. | J Altman, G D Das | J Comp Neurol | 1965 | 5861717 | Yes |
2665 | 1277 | 1277.0 | 44.74 | 44.7 | Plasma perspective on strong field multiphoton ionization. | P B Corkum | Phys Rev Lett | 1993 | 10054556 | Yes |
2666 | 1277 | 1277.0 | 34.54 | 34.5 | Neural simulation of action: a unifying mechanism for motor cognition. | M Jeannerod | Neuroimage | 2001 | 11373140 | No |
2667 | 1277 | 1277.0 | 22.46 | 22.5 | The molecular motor toolbox for intracellular transport. | Ronald D Vale | Cell | 2003 | 12600311 | No |
2668 | 1277 | 1277.0 | 41.39 | 41.4 | The epidemiology of adult obstructive sleep apnea. | Naresh M Punjabi | Proc Am Thorac Soc | 2008 | 18250205 | No |
2669 | 2554 | 1277.0 | 54.67 | 27.3 | The canonical Notch signaling pathway: unfolding the activation mechanism. | Raphael Kopan, Maria Xenia G Ilagan | Cell | 2009 | 19379690 | No |
2670 | 1277 | 1277.0 | 55.1 | 55.1 | Transcriptional architecture of the mammalian circadian clock. | Joseph S Takahashi | Nat Rev Genet | 2017 | 27990019 | No |
2671 | 1276 | 1276.0 | 27.18 | 27.2 | Sustainable hydrogen production. | John A Turner | Science | 2004 | 15310892 | Yes |
2672 | 1276 | 1276.0 | 26.9 | 26.9 | Recognition and processing of ubiquitin-protein conjugates by the proteasome. | Daniel Finley | Annu Rev Biochem | 2009 | 19489727 | No |
2673 | 1275 | 1275.0 | 55.85 | 55.9 | Biomaterial-centered infection: microbial adhesion versus tissue integration. | A G Gristina | Science | 1987 | 3629258 | Yes |
2674 | 1275 | 1275.0 | 60.83 | 60.8 | New norms of upper limb fat and muscle areas for assessment of nutritional status. | A R Frisancho | Am J Clin Nutr | 1981 | 6975564 | Yes |
2675 | 1275 | 1275.0 | 0.0 | 0.0 | Differential spectrophotometry of purine compounds by means of specific enzymes; studies of the enzymes of purine metabolism. | H M Kalckar | J Biol Chem | 1947 | 20285041 | Yes |
2676 | 7648 | 1274.7 | 191.91 | 32.0 | An obesity-associated gut microbiome with increased capacity for energy harvest. | Peter J Turnbaugh, Ruth E Ley, Michael A Mahowald, Vincent Magrini, Elaine R Mardis, Jeffrey I Gordon | Nature | 2006 | 17183312 | Yes |
2677 | 1274 | 1274.0 | 25.57 | 25.6 | Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy. | R H Schwartz | Cell | 1992 | 1335362 | No |
2678 | 1274 | 1274.0 | 20.91 | 20.9 | Antigen receptor tail clue. | M Reth | Nature | 1989 | 2927501 | Yes |
2679 | 2547 | 1273.5 | 67.19 | 33.6 | Integrins in cancer: biological implications and therapeutic opportunities. | Jay S Desgrosellier, David A Cheresh | Nat Rev Cancer | 2010 | 20029421 | No |
2680 | 2546 | 1273.0 | 63.14 | 31.6 | Neuronal plasticity: increasing the gain in pain. | C J Woolf, M W Salter | Science | 2000 | 10846153 | No |
2681 | 1273 | 1273.0 | 33.84 | 33.8 | The biochemistry and medical significance of the flavonoids. | Bent H Havsteen | Pharmacol Ther | 2002 | 12453566 | No |
2682 | 2545 | 1272.5 | 67.46 | 33.7 | Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. | Ajay Kumar Gupta, Mona Gupta | Biomaterials | 2005 | 15626447 | No |
2683 | 3817 | 1272.3 | 135.91 | 45.3 | Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. | Marina Colombo, Graça Raposo, Clotilde Théry | Annu Rev Cell Dev Biol | 2014 | 25288114 | No |
2684 | 1272 | 1272.0 | 29.25 | 29.2 | The prefrontal cortex and cognitive control. | E K Miller | Nat Rev Neurosci | 2000 | 11252769 | No |
2685 | 1272 | 1272.0 | 32.13 | 32.1 | Plasmonics: merging photonics and electronics at nanoscale dimensions. | Ekmel Ozbay | Science | 2006 | 16410515 | Yes |
2686 | 1272 | 1272.0 | 31.42 | 31.4 | Hydrogen sulphide and its therapeutic potential. | Csaba Szabó | Nat Rev Drug Discov | 2007 | 17948022 | No |
2687 | 1272 | 1272.0 | 0.0 | 0.0 | The antidiuretic hormone and the factors which determine its release. | E B Verney | Proc R Soc Lond B Biol Sci | 1947 | 18918876 | Yes |
2688 | 1272 | 1272.0 | 38.53 | 38.5 | Persister cells. | Kim Lewis | Annu Rev Microbiol | 2010 | 20528688 | No |
2689 | 2543 | 1271.5 | 48.83 | 24.4 | Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis. | M Fried, D M Crothers | Nucleic Acids Res | 1981 | 6275366 | Yes |
2690 | 2543 | 1271.5 | 58.72 | 29.4 | Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. | Kornelia Polyak, Robert A Weinberg | Nat Rev Cancer | 2009 | 19262571 | No |
2691 | 2542 | 1271.0 | 56.59 | 28.3 | The codon Adaptation Index--a measure of directional synonymous codon usage bias, and its potential applications. | P M Sharp, W H Li | Nucleic Acids Res | 1987 | 3547335 | Yes |
2692 | 2542 | 1271.0 | 50.64 | 25.3 | A rapid, sensitive, and specific method for the determination of protein in dilute solution. | W Schaffner, C Weissmann | Anal Biochem | 1973 | 4128882 | Yes |
2693 | 2542 | 1271.0 | 59.09 | 29.5 | Quorum sensing in bacteria. | M B Miller, B L Bassler | Annu Rev Microbiol | 2001 | 11544353 | No |
2694 | 2542 | 1271.0 | 73.31 | 36.7 | Alternatives for logistic regression in cross-sectional studies: an empirical comparison of models that directly estimate the prevalence ratio. | Aluísio J D Barros, Vânia N Hirakata | BMC Med Res Methodol | 2003 | 14567763 | Yes |
2695 | 5082 | 1270.5 | 112.38 | 28.1 | A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes. | Vsevolod V Rostovtsev, Luke G Green, Valery V Fokin, K Barry Sharpless | Angew Chem Int Ed Engl | 2002 | 12203546 | Yes |
2696 | 2540 | 1270.0 | 61.44 | 30.7 | Drug delivery systems: entering the mainstream. | Theresa M Allen, Pieter R Cullis | Science | 2004 | 15031496 | Yes |
2697 | 1270 | 1270.0 | 42.29 | 42.3 | Phenylpropanoid biosynthesis. | Thomas Vogt | Mol Plant | 2010 | 20035037 | No |
2698 | 1270 | 1270.0 | 117.54 | 117.5 | COVID-19 and African Americans. | Clyde W Yancy | JAMA | 2020 | 32293639 | Yes |
2699 | 2538 | 1269.0 | 76.11 | 38.1 | An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. | Sun Ho Kim, Jin Mo Chung | Pain | 1992 | 1333581 | Yes |
2700 | 2538 | 1269.0 | 57.16 | 28.6 | Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. | D A Brown, J K Rose | Cell | 1992 | 1531449 | Yes |
2701 | 1269 | 1269.0 | 34.78 | 34.8 | Tumor angiogenesis. | J Folkman | Adv Cancer Res | 1985 | 2581424 | No |
2702 | 1269 | 1269.0 | 34.27 | 34.3 | How brains beware: neural mechanisms of emotional attention. | Patrik Vuilleumier | Trends Cogn Sci | 2005 | 16289871 | Yes |
2703 | 2537 | 1268.5 | 86.15 | 43.1 | Surgical risk as related to time of intervention in the repair of intracranial aneurysms. | W E Hunt, R M Hess | J Neurosurg | 1968 | 5635959 | Yes |
2704 | 1268 | 1268.0 | 29.96 | 30.0 | Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. | Hiroshi Takayanagi | Nat Rev Immunol | 2007 | 17380158 | No |
2705 | 1268 | 1268.0 | 36.79 | 36.8 | Species concepts and species delimitation. | Kevin De Queiroz | Syst Biol | 2007 | 18027281 | Yes |
2706 | 3800 | 1266.7 | 90.49 | 30.2 | Dystrophin: the protein product of the Duchenne muscular dystrophy locus. | E P Hoffman, R H Brown, L M Kunkel | Cell | 1987 | 3319190 | Yes |
2707 | 3800 | 1266.7 | 127.59 | 42.5 | Job burnout. | C Maslach, W B Schaufeli, M P Leiter | Annu Rev Psychol | 2001 | 11148311 | Yes |
2708 | 2533 | 1266.5 | 67.85 | 33.9 | Chlorophyll fluorescence--a practical guide. | K Maxwell, G N Johnson | J Exp Bot | 2000 | 10938857 | No |
2709 | 1266 | 1266.0 | 30.49 | 30.5 | Short-term synaptic plasticity. | R S Zucker | Annu Rev Neurosci | 1989 | 2648947 | No |
2710 | 1266 | 1266.0 | 43.98 | 44.0 | PaDEL-descriptor: an open source software to calculate molecular descriptors and fingerprints. | Chun Wei Yap | J Comput Chem | 2011 | 21425294 | Yes |
2711 | 2532 | 1266.0 | 76.92 | 38.5 | Insights into the regulation of protein abundance from proteomic and transcriptomic analyses. | Christine Vogel, Edward M Marcotte | Nat Rev Genet | 2012 | 22411467 | No |
2712 | 2532 | 1266.0 | 80.01 | 40.0 | Molecular and cellular insights into T cell exhaustion. | E John Wherry, Makoto Kurachi | Nat Rev Immunol | 2015 | 26205583 | No |
2713 | 3797 | 1265.7 | 169.34 | 56.4 | In search of how people change. Applications to addictive behaviors. | J O Prochaska, C C DiClemente, J C Norcross | Am Psychol | 1992 | 1329589 | Yes |
2714 | 5062 | 1265.5 | 184.87 | 46.2 | The chemistry and applications of metal-organic frameworks. | Hiroyasu Furukawa, Kyle E Cordova, Michael O'Keeffe, Omar M Yaghi | Science | 2013 | 23990564 | Yes |
2715 | 3796 | 1265.3 | 103.07 | 34.4 | Molecular characterization of a peripheral receptor for cannabinoids. | S Munro, K L Thomas, M Abu-Shaar | Nature | 1993 | 7689702 | Yes |
2716 | 1265 | 1265.0 | 25.8 | 25.8 | Endocytosis and molecular sorting. | I Mellman | Annu Rev Cell Dev Biol | 1996 | 8970738 | No |
2717 | 1265 | 1265.0 | 36.53 | 36.5 | Deconvoluting the context-dependent role for autophagy in cancer. | Eileen White | Nat Rev Cancer | 2012 | 22534666 | No |
2718 | 2529 | 1264.5 | 9.58 | 4.8 | Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. | G J Todaro, H Green | J Cell Biol | 1963 | 13985244 | Yes |
2719 | 1264 | 1264.0 | 24.79 | 24.8 | Structure and function of intercellular junctions. | L A Staehelin | Int Rev Cytol | 1974 | 4611943 | No |
2720 | 1264 | 1264.0 | 26.02 | 26.0 | Signal transduction via the MAP kinases: proceed at your own RSK. | J Blenis | Proc Natl Acad Sci U S A | 1993 | 8392180 | No |
2721 | 1264 | 1264.0 | 21.59 | 21.6 | Cancer susceptibility and the functions of BRCA1 and BRCA2. | Ashok R Venkitaraman | Cell | 2002 | 11832208 | No |
2722 | 1263 | 1263.0 | 32.16 | 32.2 | Rapid evolution of a protein in vitro by DNA shuffling. | W P Stemmer | Nature | 1994 | 8047147 | Yes |
2723 | 1263 | 1263.0 | 31.54 | 31.5 | Apoptosis. | J J Cohen | Immunol Today | 1993 | 8466628 | No |
2724 | 1263 | 1263.0 | 34.94 | 34.9 | Regulation of glutathione synthesis. | Shelly C Lu | Mol Aspects Med | 2009 | 18601945 | No |
2725 | 2526 | 1263.0 | 80.59 | 40.3 | DPARSF: A MATLAB Toolbox for "Pipeline" Data Analysis of Resting-State fMRI. | Yan Chao-Gan, Zang Yu-Feng | Front Syst Neurosci | 2010 | 20577591 | Yes |
2726 | 1262 | 1262.0 | 36.24 | 36.2 | A Wilcoxon-type test for trend. | J Cuzick | Stat Med | 1985 | 3992076 | Yes |
2727 | 2523 | 1261.5 | 49.01 | 24.5 | CpG islands in vertebrate genomes. | M Gardiner-Garden, M Frommer | J Mol Biol | 1987 | 3656447 | Yes |
2728 | 2523 | 1261.5 | 44.49 | 22.2 | The DNA damage response: putting checkpoints in perspective. | B B Zhou, S J Elledge | Nature | 2000 | 11100718 | No |
2729 | 1261 | 1261.0 | 14.13 | 14.1 | A restriction point for control of normal animal cell proliferation. | A B Pardee | Proc Natl Acad Sci U S A | 1974 | 4524638 | Yes |
2730 | 1261 | 1261.0 | 31.31 | 31.3 | Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution. | J Deisenhofer | Biochemistry | 1981 | 7236608 | Yes |
2731 | 1261 | 1261.0 | 25.8 | 25.8 | SETOR: hardware-lighted three-dimensional solid model representations of macromolecules. | S V Evans | J Mol Graph | 1993 | 8347566 | Yes |
2732 | 2522 | 1261.0 | 62.03 | 31.0 | Pharmacology and functions of metabotropic glutamate receptors. | P J Conn, J P Pin | Annu Rev Pharmacol Toxicol | 1997 | 9131252 | No |
2733 | 1261 | 1261.0 | 25.27 | 25.3 | Searching for genetic determinants in the new millennium. | N J Risch | Nature | 2000 | 10866211 | No |
2734 | 2522 | 1261.0 | 51.53 | 25.8 | Tumorigenesis and the angiogenic switch. | Gabriele Bergers, Laura E Benjamin | Nat Rev Cancer | 2003 | 12778130 | No |
2735 | 1260 | 1260.0 | 33.75 | 33.8 | Signaling through phosphatidylcholine breakdown. | J H Exton | J Biol Chem | 1990 | 2104616 | No |
2736 | 2520 | 1260.0 | 66.91 | 33.5 | Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction. | J L Weber, P E May | Am J Hum Genet | 1989 | 2916582 | Yes |
2737 | 1260 | 1260.0 | 31.58 | 31.6 | The effective period of preventive antibiotic action in experimental incisions and dermal lesions. | J F Burke | Surgery | 1961 | 16722001 | Yes |
2738 | 2518 | 1259.0 | 68.83 | 34.4 | Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. | Taro Kawai, Shizuo Akira | Immunity | 2011 | 21616434 | No |
2739 | 3776 | 1258.7 | 90.03 | 30.0 | Thresholding of statistical maps in functional neuroimaging using the false discovery rate. | Christopher R Genovese, Nicole A Lazar, Thomas Nichols | Neuroimage | 2002 | 11906227 | Yes |
2740 | 2517 | 1258.5 | 56.22 | 28.1 | Can the pharmaceutical industry reduce attrition rates? | Ismail Kola, John Landis | Nat Rev Drug Discov | 2004 | 15286737 | No |
2741 | 2517 | 1258.5 | 94.79 | 47.4 | Liposomal drug delivery systems: from concept to clinical applications. | Theresa M Allen, Pieter R Cullis | Adv Drug Deliv Rev | 2013 | 23036225 | No |
2742 | 1258 | 1258.0 | 27.8 | 27.8 | Life, death, and the pursuit of apoptosis. | E White | Genes Dev | 1996 | 8557188 | No |
2743 | 1258 | 1258.0 | 35.59 | 35.6 | Plant productivity and environment. | J S Boyer | Science | 1982 | 17808529 | Yes |
2744 | 1258 | 1258.0 | 0.0 | 0.0 | A simple objective technique for measuring flexibility in thinking. | E A Berg | J Gen Psychol | 1948 | 18889466 | Yes |
2745 | 1258 | 1258.0 | 40.19 | 40.2 | Tumor delivery of macromolecular drugs based on the EPR effect. | Vladimir Torchilin | Adv Drug Deliv Rev | 2011 | 20304019 | No |
2746 | 1258 | 1258.0 | 72.62 | 72.6 | DLS and zeta potential - What they are and what they are not? | Sourav Bhattacharjee | J Control Release | 2016 | 27297779 | No |
2747 | 1257 | 1257.0 | 35.9 | 35.9 | Strategy and tactics in protein chemistry. | B S Hartley | Biochem J | 1970 | 4923920 | No |
2748 | 2514 | 1257.0 | 77.62 | 38.8 | Modeling and comparison of dissolution profiles. | P Costa, J M Sousa Lobo | Eur J Pharm Sci | 2001 | 11297896 | No |
2749 | 5027 | 1256.8 | 144.63 | 36.2 | Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma. | N Weidner, J P Semple, W R Welch, J Folkman | N Engl J Med | 1991 | 1701519 | Yes |
2750 | 2513 | 1256.5 | 152.52 | 76.3 | A joint coordinate system for the clinical description of three-dimensional motions: application to the knee. | E S Grood, W J Suntay | J Biomech Eng | 1983 | 6865355 | Yes |
2751 | 1256 | 1256.0 | 26.21 | 26.2 | Nucleic acid junctions and lattices. | N C Seeman | J Theor Biol | 1982 | 6188926 | Yes |
2752 | 1256 | 1256.0 | 36.03 | 36.0 | Peptide antibiotics and their role in innate immunity. | H G Boman | Annu Rev Immunol | 1995 | 7612236 | No |
2753 | 1256 | 1256.0 | 29.92 | 29.9 | Somatostatin and its receptor family. | Y C Patel | Front Neuroendocrinol | 1999 | 10433861 | No |
2754 | 1256 | 1256.0 | 29.53 | 29.5 | Reactive oxygen radicals in signaling and damage in the ischemic brain. | P H Chan | J Cereb Blood Flow Metab | 2001 | 11149664 | No |
2755 | 1256 | 1256.0 | 62.2 | 62.2 | Biological roles of glycans. | Ajit Varki | Glycobiology | 2017 | 27558841 | No |
2756 | 1255 | 1255.0 | 53.85 | 53.9 | Environmentally induced oxidative stress in aquatic animals. | Volodymyr I Lushchak | Aquat Toxicol | 2011 | 21074869 | No |
2757 | 3764 | 1254.7 | 111.03 | 37.0 | The functional anatomy of basal ganglia disorders. | R L Albin, A B Young, J B Penney | Trends Neurosci | 1989 | 2479133 | No |
2758 | 2509 | 1254.5 | 72.75 | 36.4 | Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. | J I Morgan, T Curran | Annu Rev Neurosci | 1991 | 1903243 | No |
2759 | 2509 | 1254.5 | 50.95 | 25.5 | ERBB receptors and cancer: the complexity of targeted inhibitors. | Nancy E Hynes, Heidi A Lane | Nat Rev Cancer | 2005 | 15864276 | No |
2760 | 1254 | 1254.0 | 34.23 | 34.2 | Internal models for motor control and trajectory planning. | M Kawato | Curr Opin Neurobiol | 1999 | 10607637 | No |
2761 | 2507 | 1253.5 | 47.09 | 23.5 | The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. | T Maehama, J E Dixon | J Biol Chem | 1998 | 9593664 | Yes |
2762 | 2505 | 1252.5 | 57.92 | 29.0 | DNA sequence analysis with a modified bacteriophage T7 DNA polymerase. | S Tabor, C C Richardson | Proc Natl Acad Sci U S A | 1987 | 3474623 | Yes |
2763 | 1252 | 1252.0 | 42.08 | 42.1 | Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells. | R Lotan | Biochim Biophys Acta | 1980 | 6989400 | No |
2764 | 3756 | 1252.0 | 112.08 | 37.4 | Oxidants, antioxidants, and the degenerative diseases of aging. | B N Ames, M K Shigenaga, T M Hagen | Proc Natl Acad Sci U S A | 1993 | 8367443 | No |
2765 | 1252 | 1252.0 | 24.77 | 24.8 | STATs: signal transducers and activators of transcription. | J N Ihle | Cell | 1996 | 8608586 | No |
2766 | 1252 | 1252.0 | 33.1 | 33.1 | Persister cells, dormancy and infectious disease. | Kim Lewis | Nat Rev Microbiol | 2007 | 17143318 | No |
2767 | 1251 | 1251.0 | 34.78 | 34.8 | Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes--a meta-analysis. | P Vestergaard | Osteoporos Int | 2007 | 17068657 | No |
2768 | 2501 | 1250.5 | 213.13 | 106.6 | Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: retrospective and prospective analyses. | R B Gustilo, J T Anderson | J Bone Joint Surg Am | 1976 | 773941 | Yes |
2769 | 1250 | 1250.0 | 27.11 | 27.1 | S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles. | R Donato | Int J Biochem Cell Biol | 2001 | 11390274 | No |
2770 | 1250 | 1250.0 | 26.75 | 26.8 | Molecular physiology of low-voltage-activated t-type calcium channels. | Edward Perez-Reyes | Physiol Rev | 2003 | 12506128 | No |
2771 | 2500 | 1250.0 | 63.74 | 31.9 | Hydrogels for tissue engineering: scaffold design variables and applications. | Jeanie L Drury, David J Mooney | Biomaterials | 2003 | 12922147 | No |
2772 | 3747 | 1249.0 | 136.95 | 45.6 | Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. | C J Caspersen, K E Powell, G M Christenson | Public Health Rep | 1985 | 3920711 | Yes |
2773 | 1249 | 1249.0 | 62.7 | 62.7 | Assessment of chronic pain. I. Aspects of the reliability and validity of the visual analogue scale. | Anna Maria Carlsson | Pain | 1983 | 6602967 | Yes |
2774 | 2498 | 1249.0 | 68.87 | 34.4 | Nitric oxide synthases: roles, tolls, and controls. | C Nathan, Q W Xie | Cell | 1994 | 7522969 | No |
2775 | 1249 | 1249.0 | 42.63 | 42.6 | Inhibition and facilitation of nucleic acid amplification. | I G Wilson | Appl Environ Microbiol | 1997 | 9327537 | No |
2776 | 1249 | 1249.0 | 26.0 | 26.0 | The roles of intracellular protein-degradation pathways in neurodegeneration. | David C Rubinsztein | Nature | 2006 | 17051204 | No |
2777 | 3745 | 1248.3 | 103.97 | 34.7 | Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. | Günter Oberdörster, Eva Oberdörster, Jan Oberdörster | Environ Health Perspect | 2005 | 16002369 | No |
2778 | 13726 | 1247.8 | 328.18 | 29.8 | New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. | P Therasse, S G Arbuck, E A Eisenhauer, J Wanders, R S Kaplan, L Rubinstein, J Verweij, M Van Glabbeke, A T van Oosterom, M C Christian, S G Gwyther | J Natl Cancer Inst | 2000 | 10655437 | No |
2779 | 4991 | 1247.8 | 104.72 | 26.2 | Interleukin-10 and the interleukin-10 receptor. | K W Moore, R de Waal Malefyt, R L Coffman, A O'Garra | Annu Rev Immunol | 2001 | 11244051 | No |
2780 | 4990 | 1247.5 | 116.01 | 29.0 | Autophagy fights disease through cellular self-digestion. | Noboru Mizushima, Beth Levine, Ana Maria Cuervo, Daniel J Klionsky | Nature | 2008 | 18305538 | No |
2781 | 1247 | 1247.0 | 82.61 | 82.6 | The problem of rigor in qualitative research. | M Sandelowski | ANS Adv Nurs Sci | 1986 | 3083765 | Yes |
2782 | 1247 | 1247.0 | 57.43 | 57.4 | A cognitive approach to panic. | D M Clark | Behav Res Ther | 1986 | 3741311 | Yes |
2783 | 2494 | 1247.0 | 48.63 | 24.3 | Gene silencing in cancer in association with promoter hypermethylation. | James G Herman, Stephen B Baylin | N Engl J Med | 2003 | 14627790 | No |
2784 | 2494 | 1247.0 | 62.82 | 31.4 | Nanostructures in biodiagnostics. | Nathaniel L Rosi, Chad A Mirkin | Chem Rev | 2005 | 15826019 | No |
2785 | 1247 | 1247.0 | 38.32 | 38.3 | Understanding diagnostic tests 3: Receiver operating characteristic curves. | Anthony K Akobeng | Acta Paediatr | 2007 | 17376185 | No |
2786 | 3741 | 1247.0 | 295.42 | 98.5 | Occurrence of the potent mutagens 2- nitrobenzanthrone and 3-nitrobenzanthrone in fine airborne particles. | Aldenor G Santos, Gisele O da Rocha, Jailson B de Andrade | Sci Rep | 2019 | 30626917 | Yes |
2787 | 1246 | 1246.0 | 32.67 | 32.7 | The lipocalin protein family: structure and function. | D R Flower | Biochem J | 1996 | 8761444 | No |
2788 | 1246 | 1246.0 | 24.42 | 24.4 | Cytokines induce the development of functionally heterogeneous T helper cell subsets. | A O'Garra | Immunity | 1998 | 9529145 | No |
2789 | 1246 | 1246.0 | 90.06 | 90.1 | SARS-CoV-2 vaccines in development. | Florian Krammer | Nature | 2020 | 32967006 | No |
2790 | 1245 | 1245.0 | 41.89 | 41.9 | How is the level of free arachidonic acid controlled in mammalian cells? | R F Irvine | Biochem J | 1982 | 6810878 | No |
2791 | 1245 | 1245.0 | 34.6 | 34.6 | The effects of stressful life events on depression. | R C Kessler | Annu Rev Psychol | 1997 | 9046559 | No |
2792 | 1245 | 1245.0 | 28.23 | 28.2 | Evaluating medication effects outside of clinical trials: new-user designs. | Wayne A Ray | Am J Epidemiol | 2003 | 14585769 | Yes |
2793 | 1245 | 1245.0 | 31.28 | 31.3 | TNF-mediated inflammatory disease. | J R Bradley | J Pathol | 2008 | 18161752 | No |
2794 | 2489 | 1244.5 | 63.3 | 31.6 | Genetic dissection of complex traits. | E S Lander, N J Schork | Science | 1994 | 8091226 | No |
2795 | 1244 | 1244.0 | 23.46 | 23.5 | Neuron-glia relationship during granule cell migration in developing cerebellar cortex. A Golgi and electronmicroscopic study in Macacus Rhesus. | P Rakic | J Comp Neurol | 1971 | 4101340 | Yes |
2796 | 2488 | 1244.0 | 61.66 | 30.8 | Molecular mechanisms of action of steroid/thyroid receptor superfamily members. | M J Tsai, B W O'Malley | Annu Rev Biochem | 1994 | 7979245 | No |
2797 | 2488 | 1244.0 | 94.53 | 47.3 | Cronbach's alpha. | J M Bland, D G Altman | BMJ | 1997 | 9055718 | Yes |
2798 | 1244 | 1244.0 | 30.81 | 30.8 | Optimal experimental design for event-related fMRI. | A M Dale | Hum Brain Mapp | 1999 | 10524601 | Yes |
2799 | 7463 | 1243.8 | 215.36 | 35.9 | Free radicals and antioxidants in normal physiological functions and human disease. | Marian Valko, Dieter Leibfritz, Jan Moncol, Mark T D Cronin, Milan Mazur, Joshua Telser | Int J Biochem Cell Biol | 2007 | 16978905 | No |
2800 | 1243 | 1243.0 | 28.5 | 28.5 | Optical microcavities. | Kerry J Vahala | Nature | 2003 | 12917698 | Yes |
2801 | 1243 | 1243.0 | 0.0 | 0.0 | Intra-sexual selection in Drosophila. | A J Bateman | Heredity (Edinb) | 1948 | 18103134 | Yes |
2802 | 2485 | 1242.5 | 90.22 | 45.1 | The stunned myocardium: prolonged, postischemic ventricular dysfunction. | E Braunwald, R A Kloner | Circulation | 1982 | 6754130 | No |
2803 | 2485 | 1242.5 | 65.6 | 32.8 | Epidemiology and outcomes of osteoporotic fractures. | Steven R Cummings, L Joseph Melton | Lancet | 2002 | 12049882 | No |
2804 | 2483 | 1241.5 | 64.67 | 32.3 | Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. | Barry J Everitt, Trevor W Robbins | Nat Neurosci | 2005 | 16251991 | No |
2805 | 1241 | 1241.0 | 30.22 | 30.2 | Program DYNAFIT for the analysis of enzyme kinetic data: application to HIV proteinase. | P Kuzmic | Anal Biochem | 1996 | 8660575 | Yes |
2806 | 1241 | 1241.0 | 35.87 | 35.9 | Invasive aspergillosis. | D W Denning | Clin Infect Dis | 1998 | 9564455 | No |
2807 | 2481 | 1240.5 | 61.19 | 30.6 | Hydrogels for tissue engineering. | K Y Lee, D J Mooney | Chem Rev | 2001 | 11710233 | No |
2808 | 3721 | 1240.3 | 116.35 | 38.8 | MR diffusion tensor spectroscopy and imaging. | P J Basser, J Mattiello, D LeBihan | Biophys J | 1994 | 8130344 | Yes |
2809 | 1240 | 1240.0 | 37.81 | 37.8 | Calcium channel modulation by neurotransmitters, enzymes and drugs. | H Reuter | Nature | 1983 | 6131381 | No |
2810 | 1240 | 1240.0 | 35.85 | 35.9 | Subcutaneous and visceral adipose tissue: structural and functional differences. | M Mohsen Ibrahim | Obes Rev | 2010 | 19656312 | No |
2811 | 3718 | 1239.3 | 87.14 | 29.0 | Global and societal implications of the diabetes epidemic. | P Zimmet, K G Alberti, J Shaw | Nature | 2001 | 11742409 | No |
2812 | 6196 | 1239.2 | 284.3 | 56.9 | BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs. | Felipe A Simão, Robert M Waterhouse, Panagiotis Ioannidis, Evgenia V Kriventseva, Evgeny M Zdobnov | Bioinformatics | 2015 | 26059717 | Yes |
2813 | 1239 | 1239.0 | 26.02 | 26.0 | Antigen-presenting function of the macrophage. | E R Unanue | Annu Rev Immunol | 1984 | 6242349 | No |
2814 | 1239 | 1239.0 | 31.81 | 31.8 | Drug delivery and targeting. | R Langer | Nature | 1998 | 9579855 | No |
2815 | 1239 | 1239.0 | 0.0 | 0.0 | A modification of receptor theory. | R P Stephenson | Br J Pharmacol Chemother | 1956 | 13383117 | Yes |
2816 | 2477 | 1238.5 | 79.56 | 39.8 | The short-form version of the Depression Anxiety Stress Scales (DASS-21): construct validity and normative data in a large non-clinical sample. | Julie D Henry, John R Crawford | Br J Clin Psychol | 2005 | 16004657 | Yes |
2817 | 1238 | 1238.0 | 30.08 | 30.1 | Primate anterior cingulate cortex: where motor control, drive and cognition interface. | T Paus | Nat Rev Neurosci | 2001 | 11389475 | No |
2818 | 1238 | 1238.0 | 38.02 | 38.0 | Risk and maintenance factors for eating pathology: a meta-analytic review. | Eric Stice | Psychol Bull | 2002 | 12206196 | No |
2819 | 1238 | 1238.0 | 26.42 | 26.4 | Assortative mixing in networks. | M E J Newman | Phys Rev Lett | 2002 | 12443515 | Yes |
2820 | 1238 | 1238.0 | 30.02 | 30.0 | Electrochemiluminescence (ECL). | Mark M Richter | Chem Rev | 2004 | 15186186 | No |
2821 | 1238 | 1238.0 | 38.75 | 38.8 | Nanobodies: natural single-domain antibodies. | Serge Muyldermans | Annu Rev Biochem | 2013 | 23495938 | No |
2822 | 2475 | 1237.5 | 47.98 | 24.0 | Proliferation, cell cycle and apoptosis in cancer. | G I Evan, K H Vousden | Nature | 2001 | 11357141 | No |
2823 | 2475 | 1237.5 | 53.18 | 26.6 | Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. | Eugenia E Calle, Rudolf Kaaks | Nat Rev Cancer | 2004 | 15286738 | No |
2824 | 6187 | 1237.4 | 248.2 | 49.6 | The Phyre2 web portal for protein modeling, prediction and analysis. | Lawrence A Kelley, Stefans Mezulis, Christopher M Yates, Mark N Wass, Michael J E Sternberg | Nat Protoc | 2015 | 25950237 | Yes |
2825 | 8661 | 1237.3 | 219.05 | 31.3 | Integrative genomics viewer. | James T Robinson, Helga Thorvaldsdóttir, Wendy Winckler, Mitchell Guttman, Eric S Lander, Gad Getz, Jill P Mesirov | Nat Biotechnol | 2011 | 21221095 | Yes |
2826 | 2474 | 1237.0 | 47.74 | 23.9 | Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. | C W Greider, E H Blackburn | Cell | 1985 | 3907856 | Yes |
2827 | 1237 | 1237.0 | 47.78 | 47.8 | Minority stress and mental health in gay men. | I H Meyer | J Health Soc Behav | 1995 | 7738327 | Yes |
2828 | 3711 | 1237.0 | 141.14 | 47.0 | Visible light photoredox catalysis with transition metal complexes: applications in organic synthesis. | Christopher K Prier, Danica A Rankic, David W C MacMillan | Chem Rev | 2013 | 23509883 | No |
2829 | 2473 | 1236.5 | 53.42 | 26.7 | The role of polyamines in the neutralization of bacteriophage deoxyribonucleic acid. | B N Ames, D T Dubin | J Biol Chem | 1960 | 13793161 | Yes |
2830 | 2473 | 1236.5 | 62.37 | 31.2 | Epidemiology of Parkinson's disease. | Lonneke M L de Lau, Monique M B Breteler | Lancet Neurol | 2006 | 16713924 | No |
2831 | 1236 | 1236.0 | 0.0 | 0.0 | Sequential tests for the detection of linkage. | N E Morton | Am J Hum Genet | 1955 | 13258560 | Yes |
2832 | 1236 | 1236.0 | 32.43 | 32.4 | Thermo- and pH-responsive polymers in drug delivery. | Dirk Schmaljohann | Adv Drug Deliv Rev | 2006 | 17125884 | No |
2833 | 2470 | 1235.0 | 101.71 | 50.9 | Reading senseless sentences: brain potentials reflect semantic incongruity. | M Kutas, S A Hillyard | Science | 1980 | 7350657 | Yes |
2834 | 1235 | 1235.0 | 35.16 | 35.2 | Varieties of impulsivity. | J L Evenden | Psychopharmacology (Berl) | 1999 | 10550486 | No |
2835 | 1235 | 1235.0 | 32.01 | 32.0 | Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome: a summary of the evidence. | Earl S Ford | Diabetes Care | 2005 | 15983333 | No |
2836 | 2469 | 1234.5 | 48.37 | 24.2 | Checkpoints: controls that ensure the order of cell cycle events. | L H Hartwell, T A Weinert | Science | 1989 | 2683079 | No |
2837 | 2469 | 1234.5 | 103.56 | 51.8 | Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities. | Roel Nusse, Hans Clevers | Cell | 2017 | 28575679 | No |
2838 | 3703 | 1234.3 | 71.62 | 23.9 | Exosomes: composition, biogenesis and function. | Clotilde Théry, Laurence Zitvogel, Sebastian Amigorena | Nat Rev Immunol | 2002 | 12154376 | No |
2839 | 1234 | 1234.0 | 51.38 | 51.4 | A cochlear frequency-position function for several species--29 years later. | D D Greenwood | J Acoust Soc Am | 1990 | 2373794 | Yes |
2840 | 1234 | 1234.0 | 0.0 | 0.0 | The relation of the trail making test to organic brain damage. | R M Reitan | J Consult Psychol | 1955 | 13263471 | Yes |
2841 | 1234 | 1234.0 | 34.92 | 34.9 | Targeting recovery: priorities of the spinal cord-injured population. | Kim D Anderson | J Neurotrauma | 2004 | 15672628 | Yes |
2842 | 1234 | 1234.0 | 46.55 | 46.5 | Microtiter dish biofilm formation assay. | George A O'Toole | J Vis Exp | 2011 | 21307833 | Yes |
2843 | 8637 | 1233.9 | 254.52 | 36.4 | Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. | H P Adams, B H Bendixen, L J Kappelle, J Biller, B B Love, D L Gordon, E E Marsh | Stroke | 1993 | 7678184 | Yes |
2844 | 2467 | 1233.5 | 66.14 | 33.1 | Meeting of minds: the medial frontal cortex and social cognition. | David M Amodio, Chris D Frith | Nat Rev Neurosci | 2006 | 16552413 | No |
2845 | 2467 | 1233.5 | 66.32 | 33.2 | Increasing incidence of thyroid cancer in the United States, 1973-2002. | Louise Davies, H Gilbert Welch | JAMA | 2006 | 16684987 | Yes |
2846 | 1233 | 1233.0 | 32.45 | 32.5 | Low density lipoprotein oxidation and its pathobiological significance. | D Steinberg | J Biol Chem | 1997 | 9261091 | No |
2847 | 1233 | 1233.0 | 40.34 | 40.3 | Function and information content of DNA methylation. | Dirk Schübeler | Nature | 2015 | 25592537 | No |
2848 | 1232 | 1232.0 | 27.34 | 27.3 | Neurobiology of Pavlovian fear conditioning. | S Maren | Annu Rev Neurosci | 2001 | 11520922 | No |
2849 | 2463 | 1231.5 | 68.24 | 34.1 | Ageing and Parkinson's disease: substantia nigra regional selectivity. | J M Fearnley, A J Lees | Brain | 1991 | 1933245 | Yes |
2850 | 2463 | 1231.5 | 67.68 | 33.8 | The cognitive control of emotion. | Kevin N Ochsner, James J Gross | Trends Cogn Sci | 2005 | 15866151 | No |
2851 | 4926 | 1231.5 | 130.36 | 32.6 | Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. | Michael J Pencina, Ralph B D'Agostino, Ralph B D'Agostino, Ramachandran S Vasan | Stat Med | 2008 | 17569110 | Yes |
2852 | 6157 | 1231.4 | 192.72 | 38.5 | Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. | J S Beckman, T W Beckman, J Chen, P A Marshall, B A Freeman | Proc Natl Acad Sci U S A | 1990 | 2154753 | Yes |
2853 | 3694 | 1231.3 | 103.85 | 34.6 | The Patient Health Questionnaire-2: validity of a two-item depression screener. | Kurt Kroenke, Robert L Spitzer, Janet B W Williams | Med Care | 2003 | 14583691 | Yes |
2854 | 1231 | 1231.0 | 38.48 | 38.5 | Antioxidants in human health and disease. | B Halliwell | Annu Rev Nutr | 1996 | 8839918 | No |
2855 | 1230 | 1230.0 | 26.59 | 26.6 | Nuclear factor-kappaB: the enemy within. | Bharat B Aggarwal | Cancer Cell | 2004 | 15380510 | No |
2856 | 2460 | 1230.0 | 55.38 | 27.7 | Cellular processing of platinum anticancer drugs. | Dong Wang, Stephen J Lippard | Nat Rev Drug Discov | 2005 | 15789122 | No |
2857 | 1230 | 1230.0 | 26.42 | 26.4 | Hypoxia, HIF1 and glucose metabolism in the solid tumour. | Nicholas C Denko | Nat Rev Cancer | 2008 | 19143055 | No |
2858 | 1229 | 1229.0 | 21.73 | 21.7 | Mutation selection and the natural history of cancer. | J Cairns | Nature | 1975 | 1143315 | Yes |
2859 | 1229 | 1229.0 | 44.13 | 44.1 | Transduction of psychosocial stress into the neurobiology of recurrent affective disorder. | R M Post | Am J Psychiatry | 1992 | 1353322 | No |
2860 | 2458 | 1229.0 | 64.7 | 32.4 | A review of central 5-HT receptors and their function. | N M Barnes, T Sharp | Neuropharmacology | 1999 | 10462127 | No |
2861 | 1229 | 1229.0 | 22.78 | 22.8 | Histone-deacetylase inhibitors: novel drugs for the treatment of cancer. | Ricky W Johnstone | Nat Rev Drug Discov | 2002 | 12120280 | No |
2862 | 1229 | 1229.0 | 31.12 | 31.1 | Polymer conjugates as anticancer nanomedicines. | Ruth Duncan | Nat Rev Cancer | 2006 | 16900224 | No |
2863 | 1229 | 1229.0 | 33.35 | 33.4 | Infection in solid-organ transplant recipients. | Jay A Fishman | N Engl J Med | 2007 | 18094380 | No |
2864 | 1229 | 1229.0 | 41.77 | 41.8 | Physiological implications of hydrogen sulfide: a whiff exploration that blossomed. | Rui Wang | Physiol Rev | 2012 | 22535897 | No |
2865 | 3685 | 1228.3 | 115.02 | 38.3 | Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS. | B K Matuszewski, M L Constanzer, C M Chavez-Eng | Anal Chem | 2003 | 12964746 | Yes |
2866 | 2455 | 1227.5 | 56.87 | 28.4 | Peroxisome proliferator-activated receptors: nuclear control of metabolism. | B Desvergne, W Wahli | Endocr Rev | 1999 | 10529898 | No |
2867 | 2455 | 1227.5 | 43.4 | 21.7 | Stats: transcriptional control and biological impact. | David E Levy, J E Darnell | Nat Rev Mol Cell Biol | 2002 | 12209125 | No |
2868 | 2455 | 1227.5 | 62.31 | 31.2 | An integrative theory of locus coeruleus-norepinephrine function: adaptive gain and optimal performance. | Gary Aston-Jones, Jonathan D Cohen | Annu Rev Neurosci | 2005 | 16022602 | No |
2869 | 1227 | 1227.0 | 43.73 | 43.7 | The LMS method for constructing normalized growth standards. | T J Cole | Eur J Clin Nutr | 1990 | 2354692 | Yes |
2870 | 2454 | 1227.0 | 39.31 | 19.7 | A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. | D Tautz, C Pfeifle | Chromosoma | 1989 | 2476281 | Yes |
2871 | 1227 | 1227.0 | 55.22 | 55.2 | Continuous improvement as an ideal in health care. | D M Berwick | N Engl J Med | 1989 | 2909878 | Yes |
2872 | 1227 | 1227.0 | 33.1 | 33.1 | Current source-density method and application in cat cerebral cortex: investigation of evoked potentials and EEG phenomena. | U Mitzdorf | Physiol Rev | 1985 | 3880898 | No |
2873 | 1227 | 1227.0 | 32.12 | 32.1 | Preparation of rat liver cells. 3. Enzymatic requirements for tissue dispersion. | P O Seglen | Exp Cell Res | 1973 | 4358115 | Yes |
2874 | 2454 | 1227.0 | 48.89 | 24.4 | Community structure in social and biological networks. | M Girvan, M E J Newman | Proc Natl Acad Sci U S A | 2002 | 12060727 | No |
2875 | 1227 | 1227.0 | 40.02 | 40.0 | Photoplethysmography and its application in clinical physiological measurement. | John Allen | Physiol Meas | 2007 | 17322588 | No |
2876 | 1226 | 1226.0 | 30.72 | 30.7 | Endothelial-leukocyte adhesion molecules. | M P Bevilacqua | Annu Rev Immunol | 1993 | 8476577 | No |
2877 | 2451 | 1225.5 | 54.01 | 27.0 | Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange. | G K McMaster, G G Carmichael | Proc Natl Acad Sci U S A | 1977 | 73185 | Yes |
2878 | 2451 | 1225.5 | 63.24 | 31.6 | Biology of incretins: GLP-1 and GIP. | Laurie L Baggio, Daniel J Drucker | Gastroenterology | 2007 | 17498508 | No |
2879 | 1225 | 1225.0 | 18.52 | 18.5 | The concept of immunological surveillance. | F M Burnet | Prog Exp Tumor Res | 1970 | 4921480 | No |
2880 | 1225 | 1225.0 | 22.3 | 22.3 | Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture. | H E Ruley | Nature | 1983 | 6308473 | Yes |
2881 | 1225 | 1225.0 | 25.31 | 25.3 | MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. | R N Germain | Cell | 1994 | 8293464 | No |
2882 | 1225 | 1225.0 | 18.96 | 19.0 | The diagnosis of ischaemic heart pain and intermittent claudication in field surveys. | G A Rose | Bull World Health Organ | 1962 | 13974778 | Yes |
2883 | 1224 | 1224.0 | 26.67 | 26.7 | Heterotrimeric G proteins: organizers of transmembrane signals. | E J Neer | Cell | 1995 | 7834744 | No |
2884 | 1224 | 1224.0 | 26.12 | 26.1 | Microglia as a source and target of cytokines. | Uwe-Karsten Hanisch | Glia | 2002 | 12379902 | No |
2885 | 3672 | 1224.0 | 109.41 | 36.5 | Health benefits of physical activity: the evidence. | Darren E R Warburton, Crystal Whitney Nicol, Shannon S D Bredin | CMAJ | 2006 | 16534088 | No |
2886 | 1223 | 1223.0 | 62.85 | 62.9 | Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method. | K Satoh | Clin Chim Acta | 1978 | 719890 | Yes |
2887 | 1223 | 1223.0 | 52.32 | 52.3 | The Laboratory Rat: Relating Its Age With Human's. | Pallav Sengupta | Int J Prev Med | 2013 | 23930179 | Yes |
2888 | 2444 | 1222.0 | 65.26 | 32.6 | Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications. | M A Pfeffer, E Braunwald | Circulation | 1990 | 2138525 | No |
2889 | 1222 | 1222.0 | 28.46 | 28.5 | A likelihood approach to estimating phylogeny from discrete morphological character data. | P O Lewis | Syst Biol | 2001 | 12116640 | Yes |
2890 | 1222 | 1222.0 | 34.64 | 34.6 | T follicular helper cell differentiation, function, and roles in disease. | Shane Crotty | Immunity | 2014 | 25367570 | No |
2891 | 4885 | 1221.2 | 273.65 | 68.4 | Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm. | L A Papile, J Burstein, R Burstein, H Koffler | J Pediatr | 1978 | 305471 | Yes |
2892 | 2442 | 1221.0 | 75.42 | 37.7 | Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. | J E Hixson, D T Vernier | J Lipid Res | 1990 | 2341813 | Yes |
2893 | 1221 | 1221.0 | 48.8 | 48.8 | Bone "mass" and the "mechanostat": a proposal. | H M Frost | Anat Rec | 1987 | 3688455 | Yes |
2894 | 1221 | 1221.0 | 33.76 | 33.8 | Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections. | F Hefti | J Neurosci | 1986 | 3746405 | Yes |
2895 | 1221 | 1221.0 | 31.91 | 31.9 | Measurement of feelings using visual analogue scales. | R C Aitken | Proc R Soc Med | 1969 | 4899510 | No |
2896 | 1221 | 1221.0 | 30.82 | 30.8 | Neural systems for recognizing emotion. | Ralph Adolphs | Curr Opin Neurobiol | 2002 | 12015233 | No |
2897 | 1221 | 1221.0 | 37.51 | 37.5 | Evaluating the quality of medical care. 1966. | Avedis Donabedian | Milbank Q | 2005 | 16279964 | No |
2898 | 1221 | 1221.0 | 37.12 | 37.1 | Delirium in older persons. | Sharon K Inouye | N Engl J Med | 2006 | 16540616 | No |
2899 | 1221 | 1221.0 | 28.71 | 28.7 | Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis. | R Balfour Sartor | Nat Clin Pract Gastroenterol Hepatol | 2006 | 16819502 | No |
2900 | 1220 | 1220.0 | 45.54 | 45.5 | A cognitive model of drug urges and drug-use behavior: role of automatic and nonautomatic processes. | S T Tiffany | Psychol Rev | 1990 | 2186423 | No |
2901 | 1220 | 1220.0 | 44.48 | 44.5 | Comfortable and maximum walking speed of adults aged 20-79 years: reference values and determinants. | R W Bohannon | Age Ageing | 1997 | 9143432 | Yes |
2902 | 1220 | 1220.0 | 23.13 | 23.1 | ChIP-seq: advantages and challenges of a maturing technology. | Peter J Park | Nat Rev Genet | 2009 | 19736561 | No |
2903 | 1219 | 1219.0 | 23.57 | 23.6 | Lipid rafts: elusive or illusive? | Sean Munro | Cell | 2003 | 14622593 | No |
2904 | 1219 | 1219.0 | 27.57 | 27.6 | Production of recombinant protein therapeutics in cultivated mammalian cells. | Florian M Wurm | Nat Biotechnol | 2004 | 15529164 | No |
2905 | 1218 | 1218.0 | 43.1 | 43.1 | Experience from a multicentre stroke register: a preliminary report. | S Hatano | Bull World Health Organ | 1976 | 1088404 | Yes |
2906 | 1218 | 1218.0 | 44.71 | 44.7 | The P300 wave of the human event-related potential. | T W Picton | J Clin Neurophysiol | 1992 | 1464675 | No |
2907 | 1218 | 1218.0 | 28.58 | 28.6 | Growth factors and cancer. | S A Aaronson | Science | 1991 | 1659742 | No |
2908 | 1218 | 1218.0 | 36.02 | 36.0 | Federal funding for the study of antimicrobial resistance in nosocomial pathogens: no ESKAPE. | Louis B Rice | J Infect Dis | 2008 | 18419525 | No |
2909 | 2435 | 1217.5 | 78.6 | 39.3 | Atomic structure and chemistry of human serum albumin. | X M He, D C Carter | Nature | 1992 | 1630489 | Yes |
2910 | 1217 | 1217.0 | 25.1 | 25.1 | Platelets in atherothrombosis. | Zaverio M Ruggeri | Nat Med | 2002 | 12411949 | No |
2911 | 1217 | 1217.0 | 10.75 | 10.8 | Cumulative dose-response curves. II. Technique for the making of dose-response curves in isolated organs and the evaluation of drug parameters. | J M Van Rossum | Arch Int Pharmacodyn Ther | 1963 | 13996119 | Yes |
2912 | 1216 | 1216.0 | 59.06 | 59.1 | ROC methodology in radiologic imaging. | C E Metz | Invest Radiol | 1986 | 3095258 | No |
2913 | 1216 | 1216.0 | 44.51 | 44.5 | Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment. | S H Safe | Crit Rev Toxicol | 1994 | 8037844 | No |
2914 | 1216 | 1216.0 | 25.7 | 25.7 | Dendritic cells: unique leukocyte populations which control the primary immune response. | D N Hart | Blood | 1997 | 9345009 | No |
2915 | 1216 | 1216.0 | 22.12 | 22.1 | Kinesin and dynein superfamily proteins and the mechanism of organelle transport. | N Hirokawa | Science | 1998 | 9438838 | No |
2916 | 3648 | 1216.0 | 61.56 | 20.5 | A system for stable expression of short interfering RNAs in mammalian cells. | Thijn R Brummelkamp, René Bernards, Reuven Agami | Science | 2002 | 11910072 | Yes |
2917 | 1216 | 1216.0 | 30.79 | 30.8 | Functionalized acenes and heteroacenes for organic electronics. | John E Anthony | Chem Rev | 2006 | 17165682 | Yes |
2918 | 2432 | 1216.0 | 87.33 | 43.7 | Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. | John F Cryan, Timothy G Dinan | Nat Rev Neurosci | 2012 | 22968153 | No |
2919 | 1216 | 1216.0 | 67.21 | 67.2 | ROS Are Good. | Ron Mittler | Trends Plant Sci | 2017 | 27666517 | No |
2920 | 2431 | 1215.5 | 47.99 | 24.0 | Molecular chaperones in the cytosol: from nascent chain to folded protein. | F Ulrich Hartl, Manajit Hayer-Hartl | Science | 2002 | 11884745 | No |
2921 | 2431 | 1215.5 | 18.83 | 9.4 | The Aggregation Of Blood Platelets. | G V Born, M J Cross | J Physiol | 1963 | 14056485 | Yes |
2922 | 13369 | 1215.4 | 343.06 | 31.2 | Frailty in older adults: evidence for a phenotype. | L P Fried, C M Tangen, J Walston, A B Newman, C Hirsch, J Gottdiener, T Seeman, R Tracy, W J Kop, G Burke, M A McBurnie | J Gerontol A Biol Sci Med Sci | 2001 | 11253156 | Yes |
2923 | 1215 | 1215.0 | 27.28 | 27.3 | Brain tumors. | L M DeAngelis | N Engl J Med | 2001 | 11150363 | No |
2924 | 1215 | 1215.0 | 24.38 | 24.4 | Basement membranes: structure, assembly and role in tumour angiogenesis. | Raghu Kalluri | Nat Rev Cancer | 2003 | 12778132 | No |
2925 | 1214 | 1214.0 | 27.05 | 27.1 | Translating cell biology into therapeutic advances in Alzheimer's disease. | D J Selkoe | Nature | 1999 | 10392577 | No |
2926 | 1214 | 1214.0 | 32.32 | 32.3 | Akaike's information criterion in generalized estimating equations. | W Pan | Biometrics | 2001 | 11252586 | Yes |
2927 | 1214 | 1214.0 | 33.47 | 33.5 | Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective. | Antoine Bechara | Nat Neurosci | 2005 | 16251988 | No |
2928 | 1213 | 1213.0 | 32.66 | 32.7 | Levels of racism: a theoretic framework and a gardener's tale. | C P Jones | Am J Public Health | 2000 | 10936998 | Yes |
2929 | 1212 | 1212.0 | 24.93 | 24.9 | Morphogenetic roles of classic cadherins. | M Takeichi | Curr Opin Cell Biol | 1995 | 8573335 | No |
2930 | 2422 | 1211.0 | 39.41 | 19.7 | High resolution acrylamide gel electrophoresis of histones. | S Panyim, R Chalkley | Arch Biochem Biophys | 1969 | 5778650 | Yes |
2931 | 1211 | 1211.0 | 29.04 | 29.0 | Plant salt tolerance. | J K Zhu | Trends Plant Sci | 2001 | 11173290 | Yes |
2932 | 1211 | 1211.0 | 34.75 | 34.8 | High prevalence of vitamin D inadequacy and implications for health. | Michael F Holick | Mayo Clin Proc | 2006 | 16529140 | No |
2933 | 2422 | 1211.0 | 64.18 | 32.1 | A neurotrophic model for stress-related mood disorders. | Ronald S Duman, Lisa M Monteggia | Biol Psychiatry | 2006 | 16631126 | No |
2934 | 2422 | 1211.0 | 86.53 | 43.3 | Nitric oxide synthases: regulation and function. | Ulrich Förstermann, William C Sessa | Eur Heart J | 2012 | 21890489 | No |
2935 | 1210 | 1210.0 | 29.33 | 29.3 | Bcl-2 initiates a new category of oncogenes: regulators of cell death. | S J Korsmeyer | Blood | 1992 | 1498330 | No |
2936 | 1210 | 1210.0 | 25.14 | 25.1 | Caspase structure, proteolytic substrates, and function during apoptotic cell death. | D W Nicholson | Cell Death Differ | 1999 | 10578171 | No |
2937 | 1210 | 1210.0 | 34.35 | 34.4 | Electrochemical glucose biosensors. | Joseph Wang | Chem Rev | 2008 | 18154363 | No |
2938 | 2419 | 1209.5 | 72.66 | 36.3 | Inflammatory mechanisms in obesity. | Margaret F Gregor, Gökhan S Hotamisligil | Annu Rev Immunol | 2011 | 21219177 | No |
2939 | 3628 | 1209.3 | 178.62 | 59.5 | Assessing coping strategies: a theoretically based approach. | C S Carver, M F Scheier, J K Weintraub | J Pers Soc Psychol | 1989 | 2926629 | Yes |
2940 | 1209 | 1209.0 | 41.99 | 42.0 | Hydrophilic-interaction chromatography for the separation of peptides, nucleic acids and other polar compounds. | A J Alpert | J Chromatogr | 1990 | 2324207 | Yes |
2941 | 1209 | 1209.0 | 52.93 | 52.9 | Inflammation, metaflammation and immunometabolic disorders. | Gökhan S Hotamisligil | Nature | 2017 | 28179656 | No |
2942 | 1208 | 1208.0 | 28.68 | 28.7 | Rapid and sensitive sequence comparison with FASTP and FASTA. | W R Pearson | Methods Enzymol | 1990 | 2156132 | Yes |
2943 | 1208 | 1208.0 | 20.07 | 20.1 | Mitotic kinases as regulators of cell division and its checkpoints. | E A Nigg | Nat Rev Mol Cell Biol | 2001 | 11413462 | No |
2944 | 2416 | 1208.0 | 52.68 | 26.3 | Toll-like receptors in innate immunity. | Kiyoshi Takeda, Shizuo Akira | Int Immunol | 2005 | 15585605 | No |
2945 | 1208 | 1208.0 | 33.7 | 33.7 | Water as an active constituent in cell biology. | Philip Ball | Chem Rev | 2008 | 18095715 | No |
2946 | 2415 | 1207.5 | 128.38 | 64.2 | Sensitivity Analysis in Observational Research: Introducing the E-Value. | Tyler J VanderWeele, Peng Ding | Ann Intern Med | 2017 | 28693043 | Yes |
2947 | 6037 | 1207.4 | 147.21 | 29.4 | Jalview Version 2--a multiple sequence alignment editor and analysis workbench. | Andrew M Waterhouse, James B Procter, David M A Martin, Michèle Clamp, Geoffrey J Barton | Bioinformatics | 2009 | 19151095 | Yes |
2948 | 7243 | 1207.2 | 135.05 | 22.5 | Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. | S M Elbashir, J Harborth, W Lendeckel, A Yalcin, K Weber, T Tuschl | Nature | 2001 | 11373684 | Yes |
2949 | 1207 | 1207.0 | 38.13 | 38.1 | Linkage map of Escherichia coli K-12, edition 7. | B J Bachmann | Microbiol Rev | 1983 | 6348505 | No |
2950 | 1207 | 1207.0 | 48.45 | 48.5 | Bacterial adherence: adhesin-receptor interactions mediating the attachment of bacteria to mucosal surface. | E H Beachey | J Infect Dis | 1981 | 7014727 | No |
2951 | 1207 | 1207.0 | 23.11 | 23.1 | IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. | Yong-Jun Liu | Annu Rev Immunol | 2005 | 15771572 | No |
2952 | 1207 | 1207.0 | 37.89 | 37.9 | Clinical practice. Endometriosis. | Linda C Giudice | N Engl J Med | 2010 | 20573927 | No |
2953 | 1206 | 1206.0 | 31.58 | 31.6 | Chronic mild stress (CMS) revisited: consistency and behavioural-neurobiological concordance in the effects of CMS. | Paul Willner | Neuropsychobiology | 2005 | 16037678 | No |
2954 | 9647 | 1205.9 | 249.43 | 31.2 | A method and server for predicting damaging missense mutations. | Ivan A Adzhubei, Steffen Schmidt, Leonid Peshkin, Vasily E Ramensky, Anna Gerasimova, Peer Bork, Alexey S Kondrashov, Shamil R Sunyaev | Nat Methods | 2010 | 20354512 | Yes |
2955 | 3616 | 1205.3 | 72.52 | 24.2 | Large-scale analysis of the yeast proteome by multidimensional protein identification technology. | M P Washburn, D Wolters, J R Yates | Nat Biotechnol | 2001 | 11231557 | Yes |
2956 | 2410 | 1205.0 | 96.84 | 48.4 | The N1 wave of the human electric and magnetic response to sound: a review and an analysis of the component structure. | R Näätänen, T Picton | Psychophysiology | 1987 | 3615753 | Yes |
2957 | 1205 | 1205.0 | 28.19 | 28.2 | Intracellular protein topogenesis. | G Blobel | Proc Natl Acad Sci U S A | 1980 | 6929499 | Yes |
2958 | 2410 | 1205.0 | 59.92 | 30.0 | Rising incidence of hepatocellular carcinoma in the United States. | H B El-Serag, A C Mason | N Engl J Med | 1999 | 10072408 | Yes |
2959 | 1205 | 1205.0 | 51.42 | 51.4 | Receiver Operating Characteristic (ROC) Curve Analysis for Medical Diagnostic Test Evaluation. | Karimollah Hajian-Tilaki | Caspian J Intern Med | 2013 | 24009950 | No |
2960 | 3614 | 1204.7 | 101.71 | 33.9 | Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. | H King, R E Aubert, W H Herman | Diabetes Care | 1998 | 9727886 | Yes |
2961 | 1204 | 1204.0 | 29.24 | 29.2 | The neuropathology of schizophrenia. A critical review of the data and their interpretation. | P J Harrison | Brain | 1999 | 10219775 | No |
2962 | 4813 | 1203.2 | 111.99 | 28.0 | Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. | G L Wang, B H Jiang, E A Rue, G L Semenza | Proc Natl Acad Sci U S A | 1995 | 7539918 | Yes |
2963 | 2406 | 1203.0 | 74.18 | 37.1 | A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data. | A Ennaceur, J Delacour | Behav Brain Res | 1988 | 3228475 | Yes |
2964 | 3608 | 1202.7 | 113.56 | 37.9 | Qualitative research in health care. Analysing qualitative data. | C Pope, S Ziebland, N Mays | BMJ | 2000 | 10625273 | No |
2965 | 2405 | 1202.5 | 57.21 | 28.6 | Principles of bioactive lipid signalling: lessons from sphingolipids. | Yusuf A Hannun, Lina M Obeid | Nat Rev Mol Cell Biol | 2008 | 18216770 | No |
2966 | 1202 | 1202.0 | 29.5 | 29.5 | Automatic quantitation of localized in vivo 1H spectra with LCModel. | S W Provencher | NMR Biomed | 2001 | 11410943 | Yes |
2967 | 2404 | 1202.0 | 82.61 | 41.3 | Factors affecting wound healing. | S Guo, L A Dipietro | J Dent Res | 2010 | 20139336 | No |
2968 | 4807 | 1201.8 | 153.73 | 38.4 | Validation of a combined comorbidity index. | M Charlson, T P Szatrowski, J Peterson, J Gold | J Clin Epidemiol | 1994 | 7722560 | Yes |
2969 | 1201 | 1201.0 | 40.06 | 40.1 | Assay of intestinal disaccharidases. | A Dahlqvist | Anal Biochem | 1968 | 5636962 | Yes |
2970 | 1201 | 1201.0 | 21.33 | 21.3 | Studies on phosphatidylcholine vesicles. Formation and physical characteristics. | C Huang | Biochemistry | 1969 | 5777332 | Yes |
2971 | 1201 | 1201.0 | 25.65 | 25.6 | The finer things in X-ray diffraction data collection. | J W Pflugrath | Acta Crystallogr D Biol Crystallogr | 1999 | 10531521 | Yes |
2972 | 1201 | 1201.0 | 37.19 | 37.2 | Sensorimotor integration in human postural control. | R J Peterka | J Neurophysiol | 2002 | 12205132 | Yes |
2973 | 1201 | 1201.0 | 48.86 | 48.9 | The variable nature of cognitive control: a dual mechanisms framework. | Todd S Braver | Trends Cogn Sci | 2012 | 22245618 | Yes |
2974 | 3602 | 1200.7 | 86.49 | 28.8 | Functional diversity of helper T lymphocytes. | A K Abbas, K M Murphy, A Sher | Nature | 1996 | 8893001 | No |
2975 | 2400 | 1200.0 | 70.75 | 35.4 | Recent advances in the phencyclidine model of schizophrenia. | D C Javitt, S R Zukin | Am J Psychiatry | 1991 | 1654746 | No |
2976 | 2400 | 1200.0 | 64.12 | 32.1 | Leukocyte-endothelial adhesion molecules. | T M Carlos, J M Harlan | Blood | 1994 | 7522621 | No |
2977 | 1200 | 1200.0 | 27.12 | 27.1 | Mitochondrial transport of cations: channels, exchangers, and permeability transition. | P Bernardi | Physiol Rev | 1999 | 10508231 | No |
2978 | 1200 | 1200.0 | 24.59 | 24.6 | Fibrotic disease and the T(H)1/T(H)2 paradigm. | Thomas A Wynn | Nat Rev Immunol | 2004 | 15286725 | No |
2979 | 1200 | 1200.0 | 30.78 | 30.8 | The complex role of estrogens in inflammation. | Rainer H Straub | Endocr Rev | 2007 | 17640948 | No |
2980 | 1200 | 1200.0 | 50.41 | 50.4 | The use of the Center for Epidemiologic Studies Depression Scale in adolescents and young adults. | L S Radloff | J Youth Adolesc | 1991 | 24265004 | Yes |
2981 | 2399 | 1199.5 | 96.41 | 48.2 | Unique features of long non-coding RNA biogenesis and function. | Jeffrey J Quinn, Howard Y Chang | Nat Rev Genet | 2016 | 26666209 | No |
2982 | 2399 | 1199.5 | 101.58 | 50.8 | The Warburg Effect: How Does it Benefit Cancer Cells? | Maria V Liberti, Jason W Locasale | Trends Biochem Sci | 2016 | 26778478 | No |
2983 | 1199 | 1199.0 | 38.19 | 38.2 | The pathogenesis of sepsis. | R C Bone | Ann Intern Med | 1991 | 1872494 | No |
2984 | 2398 | 1199.0 | 53.38 | 26.7 | Transforming gene product of Rous sarcoma virus phosphorylates tyrosine. | T Hunter, B M Sefton | Proc Natl Acad Sci U S A | 1980 | 6246487 | Yes |
2985 | 1199 | 1199.0 | 38.39 | 38.4 | The Danish Register of Causes of Death. | Karin Helweg-Larsen | Scand J Public Health | 2011 | 21775346 | Yes |
2986 | 2397 | 1198.5 | 63.07 | 31.5 | Imaging cognition II: An empirical review of 275 PET and fMRI studies. | R Cabeza, L Nyberg | J Cogn Neurosci | 2000 | 10769304 | No |
2987 | 1198 | 1198.0 | 52.15 | 52.1 | Campylobacter enteritis: a "new" disease. | M B Skirrow | Br Med J | 1977 | 871765 | Yes |
2988 | 1198 | 1198.0 | 20.46 | 20.5 | Biochemical adaptations in muscle. Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle. | J O Holloszy | J Biol Chem | 1967 | 4290225 | Yes |
2989 | 1198 | 1198.0 | 31.95 | 31.9 | The emotional dog and its rational tail: a social intuitionist approach to moral judgment. | J Haidt | Psychol Rev | 2001 | 11699120 | Yes |
2990 | 2396 | 1198.0 | 68.61 | 34.3 | Titanium dioxide nanomaterials: synthesis, properties, modifications, and applications. | Xiaobo Chen, Samuel S Mao | Chem Rev | 2007 | 17590053 | Yes |
2991 | 2395 | 1197.5 | 244.7 | 122.3 | The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. | Hussin A Rothan, Siddappa N Byrareddy | J Autoimmun | 2020 | 32113704 | No |
2992 | 4789 | 1197.2 | 132.19 | 33.0 | Toxic potential of materials at the nanolevel. | Andre Nel, Tian Xia, Lutz Mädler, Ning Li | Science | 2006 | 16456071 | No |
2993 | 4789 | 1197.2 | 184.56 | 46.1 | Predicting effective microRNA target sites in mammalian mRNAs. | Vikram Agarwal, George W Bell, Jin-Wu Nam, David P Bartel | Elife | 2015 | 26267216 | Yes |
2994 | 1197 | 1197.0 | 41.01 | 41.0 | The deadly quartet. Upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension. | N M Kaplan | Arch Intern Med | 1989 | 2662932 | No |
2995 | 1197 | 1197.0 | 60.94 | 60.9 | Rating scales to assess depression in school-aged children. | M Kovacs | Acta Paedopsychiatr | 1981 | 7025571 | Yes |
2996 | 1197 | 1197.0 | 37.53 | 37.5 | Socioeconomic status and obesity. | Lindsay McLaren | Epidemiol Rev | 2007 | 17478442 | No |
2997 | 1196 | 1196.0 | 46.76 | 46.8 | Geriatric Depression Scale. | J A Yesavage | Psychopharmacol Bull | 1988 | 3249773 | Yes |
2998 | 1196 | 1196.0 | 25.91 | 25.9 | An overview of epithelio-mesenchymal transformation. | E D Hay | Acta Anat (Basel) | 1995 | 8714286 | No |
2999 | 1194 | 1194.0 | 29.6 | 29.6 | Hereditary cancer, oncogenes, and antioncogenes. | A G Knudson | Cancer Res | 1985 | 2983882 | Yes |
3000 | 1194 | 1194.0 | 27.96 | 28.0 | Matrix proteoglycans: from molecular design to cellular function. | R V Iozzo | Annu Rev Biochem | 1998 | 9759499 | No |
3001 | 1194 | 1194.0 | 31.02 | 31.0 | Q-ball imaging. | David S Tuch | Magn Reson Med | 2004 | 15562495 | Yes |
3002 | 1194 | 1194.0 | 34.63 | 34.6 | MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship. | Amy E Pasquinelli | Nat Rev Genet | 2012 | 22411466 | No |
3003 | 1193 | 1193.0 | 48.9 | 48.9 | Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). | S Safe | Crit Rev Toxicol | 1990 | 2124811 | No |
3004 | 1193 | 1193.0 | 36.73 | 36.7 | Biosynthesis and metabolism of endothelium-derived nitric oxide. | L J Ignarro | Annu Rev Pharmacol Toxicol | 1990 | 2188578 | No |
3005 | 1193 | 1193.0 | 36.02 | 36.0 | The mysteries of lipoprotein(a). | G Utermann | Science | 1989 | 2530631 | No |
3006 | 1193 | 1193.0 | 44.58 | 44.6 | The evolving concept of health literacy. | Don Nutbeam | Soc Sci Med | 2008 | 18952344 | Yes |
3007 | 4771 | 1192.8 | 130.58 | 32.6 | Measurement of the elastic properties and intrinsic strength of monolayer graphene. | Changgu Lee, Xiaoding Wei, Jeffrey W Kysar, James Hone | Science | 2008 | 18635798 | Yes |
3008 | 2385 | 1192.5 | 47.7 | 23.9 | Of mice and not men: differences between mouse and human immunology. | Javier Mestas, Christopher C W Hughes | J Immunol | 2004 | 14978070 | No |
3009 | 2385 | 1192.5 | 49.1 | 24.6 | NF-kappaB: linking inflammation and immunity to cancer development and progression. | Michael Karin, Florian R Greten | Nat Rev Immunol | 2005 | 16175180 | No |
3010 | 3577 | 1192.3 | 73.18 | 24.4 | Toll-like receptors: critical proteins linking innate and acquired immunity. | S Akira, K Takeda, T Kaisho | Nat Immunol | 2001 | 11477402 | No |
3011 | 1192 | 1192.0 | 32.86 | 32.9 | Normalization of cell responses in cat striate cortex. | D J Heeger | Vis Neurosci | 1992 | 1504027 | Yes |
3012 | 1192 | 1192.0 | 20.8 | 20.8 | Stem cells: units of development, units of regeneration, and units in evolution. | I L Weissman | Cell | 2000 | 10647940 | No |
3013 | 1192 | 1192.0 | 28.53 | 28.5 | Metabolism and functions of glutathione in brain. | R Dringen | Prog Neurobiol | 2000 | 10880854 | No |
3014 | 1191 | 1191.0 | 32.76 | 32.8 | Diversity of group types, regulation, and function of phospholipase A2. | E A Dennis | J Biol Chem | 1994 | 8175726 | No |
3015 | 1191 | 1191.0 | 33.24 | 33.2 | Papillary and follicular thyroid carcinoma. | M J Schlumberger | N Engl J Med | 1998 | 9445411 | No |
3016 | 2382 | 1191.0 | 57.95 | 29.0 | Heat-shock proteins, molecular chaperones, and the stress response: evolutionary and ecological physiology. | M E Feder, G E Hofmann | Annu Rev Physiol | 1999 | 10099689 | No |
3017 | 1191 | 1191.0 | 52.7 | 52.7 | The Colorimetric Micro-Determination Of Non-Esterified Fatty Acids In Plasma. | W G Duncombe | Clin Chim Acta | 1964 | 14122498 | Yes |
3018 | 1191 | 1191.0 | 30.55 | 30.6 | Physiology and pathophysiology of purinergic neurotransmission. | Geoffrey Burnstock | Physiol Rev | 2007 | 17429044 | No |
3019 | 2381 | 1190.5 | 49.42 | 24.7 | Atherosclerosis. the road ahead. | C K Glass, J L Witztum | Cell | 2001 | 11239408 | No |
3020 | 4761 | 1190.2 | 239.21 | 59.8 | Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range. | Xiang Wan, Wenqian Wang, Jiming Liu, Tiejun Tong | BMC Med Res Methodol | 2014 | 25524443 | Yes |
3021 | 1190 | 1190.0 | 34.64 | 34.6 | Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes. | W Sieghart | Pharmacol Rev | 1995 | 7568326 | No |
3022 | 1190 | 1190.0 | 33.9 | 33.9 | Atomic layer deposition: an overview. | Steven M George | Chem Rev | 2010 | 19947596 | Yes |
3023 | 2379 | 1189.5 | 45.38 | 22.7 | Dynamic instability of microtubule growth. | T Mitchison, M Kirschner | Nature | 1984 | 6504138 | Yes |
3024 | 4756 | 1189.0 | 137.02 | 34.3 | Place navigation impaired in rats with hippocampal lesions. | R G Morris, P Garrud, J N Rawlins, J O'Keefe | Nature | 1982 | 7088155 | Yes |
3025 | 1189 | 1189.0 | 19.3 | 19.3 | Themes and variations on ubiquitylation. | A M Weissman | Nat Rev Mol Cell Biol | 2001 | 11265246 | No |
3026 | 1189 | 1189.0 | 29.9 | 29.9 | Molecular genetics of colorectal cancer. | Eric R Fearon | Annu Rev Pathol | 2011 | 21090969 | No |
3027 | 1189 | 1189.0 | 45.28 | 45.3 | Glutathione synthesis. | Shelly C Lu | Biochim Biophys Acta | 2013 | 22995213 | No |
3028 | 2377 | 1188.5 | 61.17 | 30.6 | Humans integrate visual and haptic information in a statistically optimal fashion. | Marc O Ernst, Martin S Banks | Nature | 2002 | 11807554 | Yes |
3029 | 2377 | 1188.5 | 69.51 | 34.8 | Natural products as sources of new drugs over the last 25 years. | David J Newman, Gordon M Cragg | J Nat Prod | 2007 | 17309302 | No |
3030 | 10694 | 1188.2 | 354.37 | 39.4 | A novel potent vasoconstrictor peptide produced by vascular endothelial cells. | M Yanagisawa, H Kurihara, S Kimura, Y Tomobe, M Kobayashi, Y Mitsui, Y Yazaki, K Goto, T Masaki | Nature | 1988 | 2451132 | Yes |
3031 | 2376 | 1188.0 | 49.19 | 24.6 | Sequence logos: a new way to display consensus sequences. | T D Schneider, R M Stephens | Nucleic Acids Res | 1990 | 2172928 | Yes |
3032 | 1188 | 1188.0 | 21.45 | 21.4 | Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes. | D Hanahan | Nature | 1985 | 2986015 | Yes |
3033 | 1188 | 1188.0 | 30.13 | 30.1 | Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. | G Boden | Diabetes | 1997 | 8971073 | No |
3034 | 2376 | 1188.0 | 43.92 | 22.0 | Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. | C Li, W H Wong | Proc Natl Acad Sci U S A | 2001 | 11134512 | Yes |
3035 | 1188 | 1188.0 | 23.76 | 23.8 | Protein tyrosine phosphatases: from genes, to function, to disease. | Nicholas K Tonks | Nat Rev Mol Cell Biol | 2006 | 17057753 | No |
3036 | 5936 | 1187.2 | 141.12 | 28.2 | Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. | T R Mosmann, H Cherwinski, M W Bond, M A Giedlin, R L Coffman | J Immunol | 1986 | 2419430 | Yes |
3037 | 2374 | 1187.0 | 111.91 | 56.0 | Simultaneous single isotope radioenzymatic assay of plasma norepinephrine, epinephrine and dopamine. | J D Peuler, G A Johnson | Life Sci | 1977 | 904439 | Yes |
3038 | 2374 | 1187.0 | 66.29 | 33.1 | New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. | Jonathan B Baell, Georgina A Holloway | J Med Chem | 2010 | 20131845 | Yes |
3039 | 2373 | 1186.5 | 84.07 | 42.0 | Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells. | A Fabiato, F Fabiato | J Physiol (Paris) | 1979 | 533865 | Yes |
3040 | 1186 | 1186.0 | 34.81 | 34.8 | The structure of common mental disorders. | R F Krueger | Arch Gen Psychiatry | 1999 | 10530634 | Yes |
3041 | 1186 | 1186.0 | 59.12 | 59.1 | The new statistics: why and how. | Geoff Cumming | Psychol Sci | 2014 | 24220629 | Yes |
3042 | 5929 | 1185.8 | 198.68 | 39.7 | Posttraumatic stress disorder in the National Comorbidity Survey. | R C Kessler, A Sonnega, E Bromet, M Hughes, C B Nelson | Arch Gen Psychiatry | 1995 | 7492257 | Yes |
3043 | 4742 | 1185.5 | 194.08 | 48.5 | QUAST: quality assessment tool for genome assemblies. | Alexey Gurevich, Vladislav Saveliev, Nikolay Vyahhi, Glenn Tesler | Bioinformatics | 2013 | 23422339 | Yes |
3044 | 16595 | 1185.4 | 354.0 | 25.3 | Crystallography & NMR system: A new software suite for macromolecular structure determination. | A T Brünger, P D Adams, G M Clore, W L DeLano, P Gros, R W Grosse-Kunstleve, J S Jiang, J Kuszewski, M Nilges, N S Pannu, R J Read, L M Rice, T Simonson, G L Warren | Acta Crystallogr D Biol Crystallogr | 1998 | 9757107 | Yes |
3045 | 1185 | 1185.0 | 52.06 | 52.1 | Presynaptic regulation of the release of catecholamines. | S Z Langer | Pharmacol Rev | 1980 | 6267618 | Yes |
3046 | 1185 | 1185.0 | 23.19 | 23.2 | A microRNA as a translational repressor of APETALA2 in Arabidopsis flower development. | Xuemei Chen | Science | 2004 | 12893888 | Yes |
3047 | 1185 | 1185.0 | 24.07 | 24.1 | Evo-devo and an expanding evolutionary synthesis: a genetic theory of morphological evolution. | Sean B Carroll | Cell | 2008 | 18614008 | Yes |
3048 | 2369 | 1184.5 | 61.12 | 30.6 | Statistical tests of neutrality of mutations. | Y X Fu, W H Li | Genetics | 1993 | 8454210 | Yes |
3049 | 3552 | 1184.0 | 104.43 | 34.8 | The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. | G Blessed, B E Tomlinson, M Roth | Br J Psychiatry | 1968 | 5662937 | Yes |
3050 | 1184 | 1184.0 | 26.83 | 26.8 | Hybridization of denatured RNA transferred or dotted nitrocellulose paper. | P S Thomas | Methods Enzymol | 1983 | 6194404 | Yes |
3051 | 2368 | 1184.0 | 95.11 | 47.6 | Rapid procedure for detection and isolation of large and small plasmids. | C I Kado, S T Liu | J Bacteriol | 1981 | 7009583 | Yes |
3052 | 1184 | 1184.0 | 30.05 | 30.1 | Disorders of iron metabolism. | N C Andrews | N Engl J Med | 1999 | 10607817 | No |
3053 | 1184 | 1184.0 | 23.64 | 23.6 | Up on the tightrope: natural killer cell activation and inhibition. | Lewis L Lanier | Nat Immunol | 2008 | 18425106 | No |
3054 | 1184 | 1184.0 | 0.0 | 0.0 | Histological demonstration of mucin after periodic acid. | J F A McMANUS | Nature | 1946 | 20995486 | Yes |
3055 | 3550 | 1183.3 | 72.05 | 24.0 | Cellular survival: a play in three Akts. | S R Datta, A Brunet, M E Greenberg | Genes Dev | 1999 | 10579998 | No |
3056 | 1183 | 1183.0 | 26.26 | 26.3 | The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression. | S J Collins | Blood | 1987 | 3311197 | No |
3057 | 1183 | 1183.0 | 23.43 | 23.4 | Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. | Harold F Dvorak | J Clin Oncol | 2002 | 12409337 | No |
3058 | 1183 | 1183.0 | 34.2 | 34.2 | The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin. | R G Pertwee | Br J Pharmacol | 2008 | 17828291 | No |
3059 | 2366 | 1183.0 | 71.67 | 35.8 | Plasmonics for improved photovoltaic devices. | Harry A Atwater, Albert Polman | Nat Mater | 2010 | 20168344 | Yes |
3060 | 4729 | 1182.2 | 132.57 | 33.1 | AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. | Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan | Nat Cell Biol | 2011 | 21258367 | Yes |
3061 | 18913 | 1182.1 | 542.67 | 33.9 | New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). | E A Eisenhauer, P Therasse, J Bogaerts, L H Schwartz, D Sargent, R Ford, J Dancey, S Arbuck, S Gwyther, M Mooney, L Rubinstein, L Shankar, L Dodd, R Kaplan, D Lacombe, J Verweij | Eur J Cancer | 2009 | 19097774 | No |
3062 | 1182 | 1182.0 | 0.0 | 0.0 | Voluntary strength and fatigue. | P A Merton | J Physiol | 1954 | 13152698 | Yes |
3063 | 1182 | 1182.0 | 25.67 | 25.7 | Simple model of spiking neurons. | E M Izhikevich | IEEE Trans Neural Netw | 2003 | 18244602 | Yes |
3064 | 1182 | 1182.0 | 54.71 | 54.7 | Salience processing and insular cortical function and dysfunction. | Lucina Q Uddin | Nat Rev Neurosci | 2015 | 25406711 | No |
3065 | 2363 | 1181.5 | 65.18 | 32.6 | Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. | R G Phillips, J E LeDoux | Behav Neurosci | 1992 | 1590953 | Yes |
3066 | 1181 | 1181.0 | 45.2 | 45.2 | Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes. | H V Gelboin | Physiol Rev | 1980 | 7001511 | No |
3067 | 1181 | 1181.0 | 36.52 | 36.5 | Peritonectomy procedures. | P H Sugarbaker | Ann Surg | 1995 | 7826158 | Yes |
3068 | 1181 | 1181.0 | 36.19 | 36.2 | The somatic marker hypothesis and the possible functions of the prefrontal cortex. | A R Damasio | Philos Trans R Soc Lond B Biol Sci | 1996 | 8941953 | No |
3069 | 1181 | 1181.0 | 32.44 | 32.4 | The stress response to trauma and surgery. | J P Desborough | Br J Anaesth | 2000 | 10927999 | No |
3070 | 2362 | 1181.0 | 30.21 | 15.1 | Studies of marine planktonic diatoms. I. Cyclotella nana Hustedt, and Detonula confervacea (cleve) Gran. | R R Guillard, J H Ryther | Can J Microbiol | 1962 | 13902807 | Yes |
3071 | 1181 | 1181.0 | 20.75 | 20.8 | Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig. | G D Winter | Nature | 1962 | 14007593 | Yes |
3072 | 2362 | 1181.0 | 48.5 | 24.2 | The mammalian unfolded protein response. | Martin Schröder, Randal J Kaufman | Annu Rev Biochem | 2005 | 15952902 | No |
3073 | 1180 | 1180.0 | 65.5 | 65.5 | Nontuberculous mycobacteria and associated diseases. | E Wolinsky | Am Rev Respir Dis | 1979 | 369415 | No |
3074 | 2359 | 1179.5 | 88.0 | 44.0 | Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. | H Esterbauer, K H Cheeseman | Methods Enzymol | 1990 | 2233308 | Yes |
3075 | 2358 | 1179.0 | 68.15 | 34.1 | The low-density lipoprotein pathway and its relation to atherosclerosis. | J L Goldstein, M S Brown | Annu Rev Biochem | 1977 | 197883 | No |
3076 | 1179 | 1179.0 | 38.8 | 38.8 | Interleukin-1 and the pathogenesis of the acute-phase response. | C A Dinarello | N Engl J Med | 1984 | 6208485 | No |
3077 | 1179 | 1179.0 | 47.13 | 47.1 | The anatomy of stages of change. | A Bandura | Am J Health Promot | 1997 | 10170438 | No |
3078 | 1179 | 1179.0 | 28.43 | 28.4 | Targeting DNA topoisomerase II in cancer chemotherapy. | John L Nitiss | Nat Rev Cancer | 2009 | 19377506 | No |
3079 | 2357 | 1178.5 | 101.97 | 51.0 | Numerical index of the discriminatory ability of typing systems: an application of Simpson's index of diversity. | P R Hunter, M A Gaston | J Clin Microbiol | 1988 | 3069867 | Yes |
3080 | 4713 | 1178.2 | 147.78 | 36.9 | Epidemiology and causes of preterm birth. | Robert L Goldenberg, Jennifer F Culhane, Jay D Iams, Roberto Romero | Lancet | 2008 | 18177778 | No |
3081 | 5890 | 1178.0 | 190.76 | 38.2 | Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. | D Steinberg, S Parthasarathy, T E Carew, J C Khoo, J L Witztum | N Engl J Med | 1989 | 2648148 | No |
3082 | 1178 | 1178.0 | 38.55 | 38.5 | Checklists for improving rigour in qualitative research: a case of the tail wagging the dog? | R S Barbour | BMJ | 2001 | 11337448 | No |
3083 | 1178 | 1178.0 | 25.43 | 25.4 | The myofibroblast in wound healing and fibrocontractive diseases. | G Gabbiani | J Pathol | 2003 | 12845617 | No |
3084 | 5889 | 1177.8 | 287.72 | 57.5 | Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. | N Bellamy, W W Buchanan, C H Goldsmith, J Campbell, L W Stitt | J Rheumatol | 1988 | 3068365 | Yes |
3085 | 2355 | 1177.5 | 72.36 | 36.2 | Theoretical studies of enzymic reactions: dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme. | A Warshel, M Levitt | J Mol Biol | 1976 | 985660 | Yes |
3086 | 2355 | 1177.5 | 50.77 | 25.4 | Lymphocyte homing and homeostasis. | E C Butcher, L J Picker | Science | 1996 | 8600538 | No |
3087 | 2355 | 1177.5 | 48.6 | 24.3 | Toll-like receptors in the induction of the innate immune response. | A Aderem, R J Ulevitch | Nature | 2000 | 10963608 | No |
3088 | 1177 | 1177.0 | 34.54 | 34.5 | Analyzing the mosaic structure of genes. | J M Smith | J Mol Evol | 1992 | 1556748 | No |
3089 | 1177 | 1177.0 | 72.99 | 73.0 | Impingement lesions. | C S Neer | Clin Orthop Relat Res | 1983 | 6825348 | Yes |
3090 | 2354 | 1177.0 | 76.36 | 38.2 | Physiological parameters in laboratory animals and humans. | B Davies, T Morris | Pharm Res | 1993 | 8378254 | No |
3091 | 1177 | 1177.0 | 28.15 | 28.1 | A tension-based theory of morphogenesis and compact wiring in the central nervous system. | D C Van Essen | Nature | 1997 | 9002514 | Yes |
3092 | 1177 | 1177.0 | 30.58 | 30.6 | The neurobiology of stress: from serendipity to clinical relevance. | B S McEwen | Brain Res | 2000 | 11119695 | No |
3093 | 1177 | 1177.0 | 25.75 | 25.8 | How neutrophils kill microbes. | Anthony W Segal | Annu Rev Immunol | 2005 | 15771570 | No |
3094 | 2354 | 1177.0 | 52.48 | 26.2 | Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. | Jing Yang, Robert A Weinberg | Dev Cell | 2008 | 18539112 | No |
3095 | 3531 | 1177.0 | 90.74 | 30.2 | Methods in mammalian autophagy research. | Noboru Mizushima, Tamotsu Yoshimori, Beth Levine | Cell | 2010 | 20144757 | Yes |
3096 | 8233 | 1176.1 | 162.57 | 23.2 | Exploration, normalization, and summaries of high density oligonucleotide array probe level data. | Rafael A Irizarry, Bridget Hobbs, Francois Collin, Yasmin D Beazer-Barclay, Kristen J Antonellis, Uwe Scherf, Terence P Speed | Biostatistics | 2003 | 12925520 | Yes |
3097 | 2352 | 1176.0 | 76.43 | 38.2 | Quantitative determination of serum triglycerides by the use of enzymes. | G Bucolo, H David | Clin Chem | 1973 | 4703655 | Yes |
3098 | 1176 | 1176.0 | 30.81 | 30.8 | Bacteroides: the good, the bad, and the nitty-gritty. | Hannah M Wexler | Clin Microbiol Rev | 2007 | 17934076 | No |
3099 | 10584 | 1176.0 | 273.87 | 30.4 | MolProbity: all-atom structure validation for macromolecular crystallography. | Vincent B Chen, W Bryan Arendall, Jeffrey J Headd, Daniel A Keedy, Robert M Immormino, Gary J Kapral, Laura W Murray, Jane S Richardson, David C Richardson | Acta Crystallogr D Biol Crystallogr | 2010 | 20057044 | Yes |
3100 | 1176 | 1176.0 | 46.05 | 46.0 | A review and synthesis of the first 20 years of PET and fMRI studies of heard speech, spoken language and reading. | Cathy J Price | Neuroimage | 2012 | 22584224 | No |
3101 | 4702 | 1175.5 | 105.24 | 26.3 | Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. | J E Walker, M Saraste, M J Runswick, N J Gay | EMBO J | 1982 | 6329717 | Yes |
3102 | 1175 | 1175.0 | 34.47 | 34.5 | A human model of gastric carcinogenesis. | P Correa | Cancer Res | 1988 | 3288329 | No |
3103 | 1175 | 1175.0 | 45.84 | 45.8 | Freezing of living cells: mechanisms and implications. | P Mazur | Am J Physiol | 1984 | 6383068 | No |
3104 | 1175 | 1175.0 | 24.12 | 24.1 | Apoptosis in neurodegenerative disorders. | M P Mattson | Nat Rev Mol Cell Biol | 2000 | 11253364 | No |
3105 | 1175 | 1175.0 | 0.0 | 0.0 | Immunity to homologous grafted skin; the fate of skin homografts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye. | P B Medawar | Br J Exp Pathol | 1948 | 18865105 | Yes |
3106 | 2349 | 1174.5 | 46.0 | 23.0 | Multiple nuclear factors interact with the immunoglobulin enhancer sequences. | R Sen, D Baltimore | Cell | 1986 | 3091258 | Yes |
3107 | 2349 | 1174.5 | 42.2 | 21.1 | Hedgehog signaling in animal development: paradigms and principles. | P W Ingham, A P McMahon | Genes Dev | 2001 | 11731473 | No |
3108 | 2349 | 1174.5 | 66.4 | 33.2 | Heterogeneous photocatalyst materials for water splitting. | Akihiko Kudo, Yugo Miseki | Chem Soc Rev | 2009 | 19088977 | Yes |
3109 | 3523 | 1174.3 | 162.73 | 54.2 | Cross-cultural adaptation of health-related quality of life measures: literature review and proposed guidelines. | F Guillemin, C Bombardier, D Beaton | J Clin Epidemiol | 1993 | 8263569 | No |
3110 | 1174 | 1174.0 | 40.56 | 40.6 | An approach for the treatment of penile carcinoma. | R M Cabanas | Cancer | 1977 | 837331 | Yes |
3111 | 1174 | 1174.0 | 37.87 | 37.9 | Agents that increase the permeability of the outer membrane. | M Vaara | Microbiol Rev | 1992 | 1406489 | No |
3112 | 1174 | 1174.0 | 26.11 | 26.1 | Cadherins: a molecular family important in selective cell-cell adhesion. | M Takeichi | Annu Rev Biochem | 1990 | 2197976 | No |
3113 | 1174 | 1174.0 | 32.31 | 32.3 | The induction of pain: an integrative review. | M J Millan | Prog Neurobiol | 1999 | 9987804 | No |
3114 | 1174 | 1174.0 | 0.0 | 0.0 | A production of amino acids under possible primitive earth conditions. | S L Miller | Science | 1953 | 13056598 | Yes |
3115 | 1174 | 1174.0 | 39.87 | 39.9 | Volumetric modulated arc therapy: IMRT in a single gantry arc. | Karl Otto | Med Phys | 2008 | 18293586 | Yes |
3116 | 3519 | 1173.0 | 90.06 | 30.0 | Towards a natural system of organisms: proposal for the domains Archaea, Bacteria, and Eucarya. | C R Woese, O Kandler, M L Wheelis | Proc Natl Acad Sci U S A | 1990 | 2112744 | Yes |
3117 | 1173 | 1173.0 | 41.38 | 41.4 | Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes. | M A Lemp | CLAO J | 1995 | 8565190 | No |
3118 | 2346 | 1173.0 | 61.54 | 30.8 | The ubiquitin code. | David Komander, Michael Rape | Annu Rev Biochem | 2012 | 22524316 | No |
3119 | 2345 | 1172.5 | 201.57 | 100.8 | Radiological demarcation of cemented sockets in total hip replacement. | J G DeLee, J Charnley | Clin Orthop Relat Res | 1976 | 991504 | Yes |
3120 | 2345 | 1172.5 | 56.18 | 28.1 | Predictive coding in the visual cortex: a functional interpretation of some extra-classical receptive-field effects. | R P Rao, D H Ballard | Nat Neurosci | 1999 | 10195184 | Yes |
3121 | 2344 | 1172.0 | 73.25 | 36.6 | Antiseptics and disinfectants: activity, action, and resistance. | G McDonnell, A D Russell | Clin Microbiol Rev | 1999 | 9880479 | No |
3122 | 1172 | 1172.0 | 43.69 | 43.7 | Energy metabolism in the liver. | Liangyou Rui | Compr Physiol | 2014 | 24692138 | No |
3123 | 2343 | 1171.5 | 74.59 | 37.3 | Solubilization of membranes by detergents. | A Helenius, K Simons | Biochim Biophys Acta | 1975 | 1091302 | No |
3124 | 1171 | 1171.0 | 30.74 | 30.7 | Pathogenesis of dengue: challenges to molecular biology. | S B Halstead | Science | 1988 | 3277268 | No |
3125 | 1171 | 1171.0 | 21.84 | 21.8 | Shrinkage necrosis: a distinct mode of cellular death. | J F Kerr | J Pathol | 1971 | 4108566 | Yes |
3126 | 1171 | 1171.0 | 24.23 | 24.2 | Microsatellites: simple sequences with complex evolution. | Hans Ellegren | Nat Rev Genet | 2004 | 15153996 | No |
3127 | 3512 | 1170.7 | 84.86 | 28.3 | Astrocyte-endothelial interactions at the blood-brain barrier. | N Joan Abbott, Lars Rönnbäck, Elisabeth Hansson | Nat Rev Neurosci | 2006 | 16371949 | No |
3128 | 3510 | 1170.0 | 70.46 | 23.5 | Predicting coiled coils from protein sequences. | A Lupas, M Van Dyke, J Stock | Science | 1991 | 2031185 | Yes |
3129 | 3510 | 1170.0 | 116.95 | 39.0 | Hepatocellular carcinoma. | Alejandro Forner, Josep M Llovet, Jordi Bruix | Lancet | 2012 | 22353262 | No |
3130 | 3509 | 1169.7 | 87.92 | 29.3 | Use and abuse of HOMA modeling. | Tara M Wallace, Jonathan C Levy, David R Matthews | Diabetes Care | 2004 | 15161807 | No |
3131 | 2339 | 1169.5 | 36.84 | 18.4 | Theoretical aspects of DNA-protein interactions: co-operative and non-co-operative binding of large ligands to a one-dimensional homogeneous lattice. | J D McGhee, P H von Hippel | J Mol Biol | 1974 | 4416620 | Yes |
3132 | 2338 | 1169.0 | 52.48 | 26.2 | Adaptive protein evolution at the Adh locus in Drosophila. | J H McDonald, M Kreitman | Nature | 1991 | 1904993 | Yes |
3133 | 1169 | 1169.0 | 38.75 | 38.8 | Enhancing the quality and credibility of qualitative analysis. | M Q Patton | Health Serv Res | 1999 | 10591279 | No |
3134 | 2338 | 1169.0 | 76.39 | 38.2 | Efficacy of the Theory of Planned Behaviour: a meta-analytic review. | C J Armitage, M Conner | Br J Soc Psychol | 2001 | 11795063 | Yes |
3135 | 2337 | 1168.5 | 63.18 | 31.6 | A new local density functional for main-group thermochemistry, transition metal bonding, thermochemical kinetics, and noncovalent interactions. | Yan Zhao, Donald G Truhlar | J Chem Phys | 2006 | 17129083 | Yes |
3136 | 7010 | 1168.3 | 199.48 | 33.2 | Genome engineering using the CRISPR-Cas9 system. | F Ann Ran, Patrick D Hsu, Jason Wright, Vineeta Agarwala, David A Scott, Feng Zhang | Nat Protoc | 2013 | 24157548 | Yes |
3137 | 1168 | 1168.0 | 30.8 | 30.8 | 6-Hydroxy-dopamine induced degeneration of central monoamine neurons. | U Ungerstedt | Eur J Pharmacol | 1968 | 5718510 | Yes |
3138 | 1168 | 1168.0 | 34.85 | 34.9 | Low-molecular-weight heparins. | J I Weitz | N Engl J Med | 1997 | 9278467 | No |
3139 | 1168 | 1168.0 | 0.0 | 0.0 | A chemical method for the determination of oestriol, oestrone and oestradiol in human urine. | J B Brown | Biochem J | 1955 | 14389222 | Yes |
3140 | 1168 | 1168.0 | 22.81 | 22.8 | Telomeres and human disease: ageing, cancer and beyond. | Maria A Blasco | Nat Rev Genet | 2005 | 16136653 | No |
3141 | 2336 | 1168.0 | 70.95 | 35.5 | Stochastic relaxation, gibbs distributions, and the bayesian restoration of images. | S Geman, D Geman | IEEE Trans Pattern Anal Mach Intell | 1984 | 22499653 | Yes |
3142 | 11673 | 1167.3 | 423.6 | 42.4 | The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. | Alessandro Liberati, Douglas G Altman, Jennifer Tetzlaff, Cynthia Mulrow, Peter C Gøtzsche, John P A Ioannidis, Mike Clarke, P J Devereaux, Jos Kleijnen, David Moher | BMJ | 2009 | 19622552 | No |
3143 | 4669 | 1167.2 | 132.08 | 33.0 | Biological identifications through DNA barcodes. | Paul D N Hebert, Alina Cywinska, Shelley L Ball, Jeremy R deWaard | Proc Biol Sci | 2003 | 12614582 | Yes |
3144 | 1167 | 1167.0 | 31.3 | 31.3 | Presynaptic regulation of catecholamine release. | S Z Langer | Biochem Pharmacol | 1974 | 4617579 | No |
3145 | 1167 | 1167.0 | 106.38 | 106.4 | The analysis of errors in orthodontic measurements. | W J Houston | Am J Orthod | 1983 | 6573846 | Yes |
3146 | 1167 | 1167.0 | 35.72 | 35.7 | Context, time, and memory retrieval in the interference paradigms of Pavlovian learning. | M E Bouton | Psychol Bull | 1993 | 8346330 | No |
3147 | 1167 | 1167.0 | 0.0 | 0.0 | A simple method of increasing the adhesion of acrylic filling materials to enamel surfaces. | M G Buonocore | J Dent Res | 1955 | 13271655 | Yes |
3148 | 1167 | 1167.0 | 0.0 | 0.0 | The cytoarchitectonic organization of the spinal cord in the cat. | B Rexed | J Comp Neurol | 1952 | 14946260 | Yes |
3149 | 5833 | 1166.6 | 216.15 | 43.2 | DNA primers for amplification of mitochondrial cytochrome c oxidase subunit I from diverse metazoan invertebrates. | O Folmer, M Black, W Hoeh, R Lutz, R Vrijenhoek | Mol Mar Biol Biotechnol | 1994 | 7881515 | Yes |
3150 | 4666 | 1166.5 | 108.49 | 27.1 | Base-calling of automated sequencer traces using phred. I. Accuracy assessment. | B Ewing, L Hillier, M C Wendl, P Green | Genome Res | 1998 | 9521921 | Yes |
3151 | 3499 | 1166.3 | 78.72 | 26.2 | Molecular weight estimation of polypeptide chains by electrophoresis in SDS-polyacrylamide gels. | A L Shapiro, E Viñuela, J V Maizel | Biochem Biophys Res Commun | 1967 | 4861258 | Yes |
3152 | 1166 | 1166.0 | 35.46 | 35.5 | Platelet-rich plasma: evidence to support its use. | Robert E Marx | J Oral Maxillofac Surg | 2004 | 15085519 | No |
3153 | 1166 | 1166.0 | 44.84 | 44.8 | The biogenesis and emerging roles of circular RNAs. | Ling-Ling Chen | Nat Rev Mol Cell Biol | 2016 | 26908011 | Yes |
3154 | 1165 | 1165.0 | 35.73 | 35.7 | MOPAC: a semiempirical molecular orbital program. | J J Stewart | J Comput Aided Mol Des | 1990 | 2197373 | No |
3155 | 1165 | 1165.0 | 22.1 | 22.1 | Contingent genetic regulatory events in T lymphocyte activation. | G R Crabtree | Science | 1989 | 2783497 | Yes |
3156 | 3495 | 1165.0 | 73.25 | 24.4 | Computer visualization of three-dimensional image data using IMOD. | J R Kremer, D N Mastronarde, J R McIntosh | J Struct Biol | 1996 | 8742726 | Yes |
3157 | 1165 | 1165.0 | 31.72 | 31.7 | Pharmacology of cannabinoid CB1 and CB2 receptors. | R G Pertwee | Pharmacol Ther | 1997 | 9336020 | No |
3158 | 2330 | 1165.0 | 49.22 | 24.6 | Functions of lipid rafts in biological membranes. | D A Brown, E London | Annu Rev Cell Dev Biol | 1998 | 9891780 | No |
3159 | 1165 | 1165.0 | 31.21 | 31.2 | Core affect and the psychological construction of emotion. | James A Russell | Psychol Rev | 2003 | 12529060 | No |
3160 | 1165 | 1165.0 | 37.7 | 37.7 | On the law of effect. | R J Herrnstein | J Exp Anal Behav | 1970 | 16811440 | Yes |
3161 | 4660 | 1165.0 | 124.13 | 31.0 | Organometal halide perovskites as visible-light sensitizers for photovoltaic cells. | Akihiro Kojima, Kenjiro Teshima, Yasuo Shirai, Tsutomu Miyasaka | J Am Chem Soc | 2009 | 19366264 | Yes |
3162 | 4659 | 1164.8 | 89.58 | 22.4 | Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. | L Alexopoulou, A C Holt, R Medzhitov, R A Flavell | Nature | 2001 | 11607032 | Yes |
3163 | 6985 | 1164.2 | 237.28 | 39.5 | The occurrence of sleep-disordered breathing among middle-aged adults. | T Young, M Palta, J Dempsey, J Skatrud, S Weber, S Badr | N Engl J Med | 1993 | 8464434 | Yes |
3164 | 1164 | 1164.0 | 23.75 | 23.8 | Biogenic amines and the states of sleep. | M Jouvet | Science | 1969 | 4303225 | No |
3165 | 1164 | 1164.0 | 11.51 | 11.5 | Pathologic anatomy of the pancreas in juvenile diabetes mellitus. | W Gepts | Diabetes | 1965 | 5318831 | Yes |
3166 | 1164 | 1164.0 | 22.02 | 22.0 | Microarray data normalization and transformation. | John Quackenbush | Nat Genet | 2002 | 12454644 | No |
3167 | 1164 | 1164.0 | 31.36 | 31.4 | Production and scavenging of reactive oxygen species in chloroplasts and their functions. | Kozi Asada | Plant Physiol | 2006 | 16760493 | Yes |
3168 | 2327 | 1163.5 | 95.69 | 47.8 | Systematic review of the health benefits of physical activity and fitness in school-aged children and youth. | Ian Janssen, Allana G Leblanc | Int J Behav Nutr Phys Act | 2010 | 20459784 | Yes |
3169 | 10471 | 1163.4 | 270.22 | 30.0 | Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. | Cole Trapnell, Brian A Williams, Geo Pertea, Ali Mortazavi, Gordon Kwan, Marijke J van Baren, Steven L Salzberg, Barbara J Wold, Lior Pachter | Nat Biotechnol | 2010 | 20436464 | Yes |
3170 | 3490 | 1163.3 | 77.0 | 25.7 | Hepatocellular carcinoma. | Josep M Llovet, Andrew Burroughs, Jordi Bruix | Lancet | 2003 | 14667750 | No |
3171 | 1163 | 1163.0 | 41.95 | 42.0 | The case for motivated reasoning. | Z Kunda | Psychol Bull | 1990 | 2270237 | No |
3172 | 1163 | 1163.0 | 33.19 | 33.2 | What is synergy? | M C Berenbaum | Pharmacol Rev | 1989 | 2692037 | No |
3173 | 1163 | 1163.0 | 36.68 | 36.7 | Molecular biology of steroid hormone synthesis. | W L Miller | Endocr Rev | 1988 | 3061784 | No |
3174 | 1163 | 1163.0 | 34.75 | 34.8 | Effect of anoxia on ion distribution in the brain. | A J Hansen | Physiol Rev | 1985 | 3880896 | No |
3175 | 2326 | 1163.0 | 60.18 | 30.1 | Verification of protein structures: patterns of nonbonded atomic interactions. | C Colovos, T O Yeates | Protein Sci | 1993 | 8401235 | Yes |
3176 | 1163 | 1163.0 | 30.56 | 30.6 | Epidemiology of women and depression. | Ronald C Kessler | J Affect Disord | 2003 | 12646294 | Yes |
3177 | 1163 | 1163.0 | 51.1 | 51.1 | Preliminary Trial Of Carisoprodol In Multiple Sclerosis. | B Ashworth | Practitioner | 1964 | 14143329 | Yes |
3178 | 3488 | 1162.7 | 138.51 | 46.2 | Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves. | A DeLean, P J Munson, D Rodbard | Am J Physiol | 1978 | 686171 | Yes |
3179 | 2325 | 1162.5 | 71.46 | 35.7 | bold: The Barcode of Life Data System (http://www.barcodinglife.org). | Sujeevan Ratnasingham, Paul D N Hebert | Mol Ecol Notes | 2007 | 18784790 | Yes |
3180 | 3487 | 1162.3 | 118.83 | 39.6 | The 'Trier Social Stress Test'--a tool for investigating psychobiological stress responses in a laboratory setting. | C Kirschbaum, K M Pirke, D H Hellhammer | Neuropsychobiology | 1993 | 8255414 | Yes |
3181 | 1162 | 1162.0 | 34.26 | 34.3 | Determinants of tumor blood flow: a review. | R K Jain | Cancer Res | 1988 | 3282647 | No |
3182 | 1162 | 1162.0 | 25.8 | 25.8 | Effect of carvedilol on outcome after myocardial infarction in patients with left-ventricular dysfunction: the CAPRICORN randomised trial. | H J Dargie | Lancet | 2001 | 11356434 | Yes |
3183 | 1162 | 1162.0 | 27.9 | 27.9 | Context and behavioral processes in extinction. | Mark E Bouton | Learn Mem | 2004 | 15466298 | No |
3184 | 1162 | 1162.0 | 55.95 | 56.0 | When to use the Bonferroni correction. | Richard A Armstrong | Ophthalmic Physiol Opt | 2014 | 24697967 | No |
3185 | 2323 | 1161.5 | 79.55 | 39.8 | The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis. | G P Chrousos, P W Gold | JAMA | 1992 | 1538563 | No |
3186 | 1161 | 1161.0 | 26.77 | 26.8 | Neurons with graded response have collective computational properties like those of two-state neurons. | J J Hopfield | Proc Natl Acad Sci U S A | 1984 | 6587342 | Yes |
3187 | 1161 | 1161.0 | 39.19 | 39.2 | beta-Lactamases in laboratory and clinical resistance. | D M Livermore | Clin Microbiol Rev | 1995 | 8665470 | No |
3188 | 1161 | 1161.0 | 26.69 | 26.7 | Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms. | William C Aird | Circ Res | 2007 | 17272818 | No |
3189 | 1160 | 1160.0 | 22.07 | 22.1 | The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities. | Y Yarden | Eur J Cancer | 2001 | 11597398 | No |
3190 | 1160 | 1160.0 | 23.35 | 23.4 | Liver regeneration: from myth to mechanism. | Rebecca Taub | Nat Rev Mol Cell Biol | 2004 | 15459664 | No |
3191 | 2320 | 1160.0 | 83.97 | 42.0 | Severe sepsis and septic shock. | Derek C Angus, Tom van der Poll | N Engl J Med | 2013 | 23984731 | No |
3192 | 2320 | 1160.0 | 91.57 | 45.8 | Kraken: ultrafast metagenomic sequence classification using exact alignments. | Derrick E Wood, Steven L Salzberg | Genome Biol | 2014 | 24580807 | Yes |
3193 | 2319 | 1159.5 | 50.28 | 25.1 | Blinded by the Light: The Growing Complexity of p53. | Karen H Vousden, Carol Prives | Cell | 2009 | 19410540 | No |
3194 | 1159 | 1159.0 | 35.95 | 36.0 | Strategies of antioxidant defense. | H Sies | Eur J Biochem | 1993 | 7688300 | No |
3195 | 1159 | 1159.0 | 21.36 | 21.4 | Biological robustness. | Hiroaki Kitano | Nat Rev Genet | 2004 | 15520792 | No |
3196 | 3475 | 1158.3 | 84.63 | 28.2 | High resolution two-dimensional electrophoresis of basic as well as acidic proteins. | P Z O'Farrell, H M Goodman, P H O'Farrell | Cell | 1977 | 23215 | Yes |
3197 | 1158 | 1158.0 | 14.71 | 14.7 | Central dogma of molecular biology. | F Crick | Nature | 1970 | 4913914 | No |
3198 | 1158 | 1158.0 | 22.04 | 22.0 | RNA metabolism in the HeLa cell nucleus. | S Penman | J Mol Biol | 1966 | 5961144 | Yes |
3199 | 1158 | 1158.0 | 50.65 | 50.6 | Coping theory and research: past, present, and future. | R S Lazarus | Psychosom Med | 1993 | 8346332 | No |
3200 | 2316 | 1158.0 | 47.46 | 23.7 | Learning the parts of objects by non-negative matrix factorization. | D D Lee, H S Seung | Nature | 1999 | 10548103 | Yes |
3201 | 2316 | 1158.0 | 53.95 | 27.0 | Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival. | Josep M Llovet, Jordi Bruix | Hepatology | 2003 | 12540794 | No |
3202 | 2316 | 1158.0 | 53.47 | 26.7 | Regulation of wound healing by growth factors and cytokines. | Sabine Werner, Richard Grose | Physiol Rev | 2003 | 12843410 | No |
3203 | 1158 | 1158.0 | 17.44 | 17.4 | The Nature Of Herpes Zoster: A Long-Term Study And A New Hypothesis. | R E Hope-Simpson | Proc R Soc Med | 1965 | 14267505 | Yes |
3204 | 1158 | 1158.0 | 38.57 | 38.6 | Mediators and mechanisms of change in psychotherapy research. | Alan E Kazdin | Annu Rev Clin Psychol | 2007 | 17716046 | No |
3205 | 2315 | 1157.5 | 49.55 | 24.8 | Defining the role of mTOR in cancer. | David A Guertin, David M Sabatini | Cancer Cell | 2007 | 17613433 | No |
3206 | 1157 | 1157.0 | 52.49 | 52.5 | The problem with the phrase women and minorities: intersectionality-an important theoretical framework for public health. | Lisa Bowleg | Am J Public Health | 2012 | 22594719 | Yes |
3207 | 3470 | 1156.7 | 146.84 | 48.9 | Measurement of health status. Ascertaining the minimal clinically important difference. | R Jaeschke, J Singer, G H Guyatt | Control Clin Trials | 1989 | 2691207 | Yes |
3208 | 5779 | 1155.8 | 108.2 | 21.6 | The protein kinase complement of the human genome. | G Manning, D B Whyte, R Martinez, T Hunter, S Sudarsanam | Science | 2002 | 12471243 | No |
3209 | 3467 | 1155.7 | 107.26 | 35.8 | Evaluating the public health impact of health promotion interventions: the RE-AIM framework. | R E Glasgow, T M Vogt, S M Boles | Am J Public Health | 1999 | 10474547 | No |
3210 | 2311 | 1155.5 | 54.01 | 27.0 | Establishing, maintaining and modifying DNA methylation patterns in plants and animals. | Julie A Law, Steven E Jacobsen | Nat Rev Genet | 2010 | 20142834 | No |
3211 | 1155 | 1155.0 | 28.31 | 28.3 | The epidemiologic transition. A theory of the epidemiology of population change. | A R Omran | Milbank Mem Fund Q | 1971 | 5155251 | Yes |
3212 | 1155 | 1155.0 | 26.81 | 26.8 | Amyloid, the presenilins and Alzheimer's disease. | J Hardy | Trends Neurosci | 1997 | 9106355 | No |
3213 | 1155 | 1155.0 | 37.87 | 37.9 | Starting at the beginning: an introduction to coefficient alpha and internal consistency. | David L Streiner | J Pers Assess | 2003 | 12584072 | Yes |
3214 | 1155 | 1155.0 | 0.0 | 0.0 | Observations on the isolated phrenic nerve diaphragm preparation of the rat. | E Bulbring | Br J Pharmacol Chemother | 1946 | 20999334 | Yes |
3215 | 2309 | 1154.5 | 66.73 | 33.4 | Excitatory amino acids as a final common pathway for neurologic disorders. | S A Lipton, P A Rosenberg | N Engl J Med | 1994 | 7905600 | No |
3216 | 2309 | 1154.5 | 72.48 | 36.2 | The reward circuit: linking primate anatomy and human imaging. | Suzanne N Haber, Brian Knutson | Neuropsychopharmacology | 2010 | 19812543 | No |
3217 | 1154 | 1154.0 | 12.88 | 12.9 | Autoradiographic and histological studies of postnatal neurogenesis. IV. Cell proliferation and migration in the anterior forebrain, with special reference to persisting neurogenesis in the olfactory bulb. | J Altman | J Comp Neurol | 1969 | 5361244 | Yes |
3218 | 2308 | 1154.0 | 43.86 | 21.9 | NF-kappaB at the crossroads of life and death. | Michael Karin, Anning Lin | Nat Immunol | 2002 | 11875461 | No |
3219 | 1154 | 1154.0 | 24.37 | 24.4 | The advantages and disadvantages of being polyploid. | Luca Comai | Nat Rev Genet | 2005 | 16304599 | No |
3220 | 2307 | 1153.5 | 64.38 | 32.2 | Growth of a rat neuroblastoma cell line in serum-free supplemented medium. | J E Bottenstein, G H Sato | Proc Natl Acad Sci U S A | 1979 | 284369 | Yes |
3221 | 2307 | 1153.5 | 46.44 | 23.2 | A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. | N C Andrews, D V Faller | Nucleic Acids Res | 1991 | 2041787 | Yes |
3222 | 2307 | 1153.5 | 36.42 | 18.2 | Adenosine 3',5'-phosphate in biological materials. I. Purification and properties of cyclic 3',5'-nucleotide phosphodiesterase and use of this enzyme to characterize adenosine 3',5'-phosphate in human urine. | R W Butcher, E W Sutherland | J Biol Chem | 1962 | 13875173 | Yes |
3223 | 4613 | 1153.2 | 174.12 | 43.5 | Near-optimal probabilistic RNA-seq quantification. | Nicolas L Bray, Harold Pimentel, Páll Melsted, Lior Pachter | Nat Biotechnol | 2016 | 27043002 | Yes |
3224 | 5765 | 1153.0 | 163.7 | 32.7 | Quantitative assessment of tactile allodynia in the rat paw. | S R Chaplan, F W Bach, J W Pogrel, J M Chung, T L Yaksh | J Neurosci Methods | 1994 | 7990513 | Yes |
3225 | 1153 | 1153.0 | 24.25 | 24.2 | Stem cells in the central nervous system. | R McKay | Science | 1997 | 9082987 | No |
3226 | 1153 | 1153.0 | 22.07 | 22.1 | Mechanisms and consequences of activation of protein kinase B/Akt. | J Downward | Curr Opin Cell Biol | 1998 | 9561851 | No |
3227 | 1153 | 1153.0 | 25.17 | 25.2 | G-quartets 40 years later: from 5'-GMP to molecular biology and supramolecular chemistry. | Jeffery T Davis | Angew Chem Int Ed Engl | 2004 | 14755695 | No |
3228 | 11528 | 1152.8 | 291.06 | 29.1 | Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. | M Dominici, K Le Blanc, I Mueller, I Slaper-Cortenbach, Fc Marini, Ds Krause, Rj Deans, A Keating, Dj Prockop, Em Horwitz | Cytotherapy | 2006 | 16923606 | Yes |
3229 | 2305 | 1152.5 | 66.62 | 33.3 | Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. | P Brugada, J Brugada | J Am Coll Cardiol | 1992 | 1309182 | Yes |
3230 | 2305 | 1152.5 | 70.93 | 35.5 | Role of oxidized low density lipoprotein in atherogenesis. | J L Witztum, D Steinberg | J Clin Invest | 1991 | 1752940 | No |
3231 | 1152 | 1152.0 | 19.84 | 19.8 | Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism. | M S Wold | Annu Rev Biochem | 1997 | 9242902 | No |
3232 | 3456 | 1152.0 | 91.3 | 30.4 | Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? | Dunyaporn Trachootham, Jerome Alexandre, Peng Huang | Nat Rev Drug Discov | 2009 | 19478820 | No |
3233 | 3454 | 1151.3 | 81.01 | 27.0 | Prediction of total genetic value using genome-wide dense marker maps. | T H Meuwissen, B J Hayes, M E Goddard | Genetics | 2001 | 11290733 | Yes |
3234 | 1151 | 1151.0 | 27.27 | 27.3 | Selective coronary arteriography. I. A percutaneous transfemoral technic. | M P Judkins | Radiology | 1967 | 6048074 | Yes |
3235 | 1151 | 1151.0 | 24.32 | 24.3 | Epstein-Barr virus infection. | J I Cohen | N Engl J Med | 2000 | 10944566 | No |
3236 | 2302 | 1151.0 | 47.94 | 24.0 | Protein aggregation and neurodegenerative disease. | Christopher A Ross, Michelle A Poirier | Nat Med | 2004 | 15272267 | No |
3237 | 1151 | 1151.0 | 35.27 | 35.3 | A practical solution to the pervasive problems of p values. | Eric-Jan Wagenmakers | Psychon Bull Rev | 2007 | 18087943 | Yes |
3238 | 3453 | 1151.0 | 103.54 | 34.5 | SeaView version 4: A multiplatform graphical user interface for sequence alignment and phylogenetic tree building. | Manolo Gouy, Stéphane Guindon, Olivier Gascuel | Mol Biol Evol | 2010 | 19854763 | Yes |
3239 | 2301 | 1150.5 | 56.53 | 28.3 | Plasminogen: purification from human plasma by affinity chromatography. | D G Deutsch, E T Mertz | Science | 1970 | 5475635 | Yes |
3240 | 2301 | 1150.5 | 76.78 | 38.4 | Pharmaceuticals and personal care products in the environment: agents of subtle change? | C G Daughton, T A Ternes | Environ Health Perspect | 1999 | 10592150 | No |
3241 | 2301 | 1150.5 | 43.54 | 21.8 | Rho GTPases: biochemistry and biology. | Aron B Jaffe, Alan Hall | Annu Rev Cell Dev Biol | 2005 | 16212495 | No |
3242 | 1150 | 1150.0 | 36.0 | 36.0 | Relations between the statistics of natural images and the response properties of cortical cells. | D J Field | J Opt Soc Am A | 1987 | 3430225 | Yes |
3243 | 1150 | 1150.0 | 0.0 | 0.0 | A sensitive method for the assay of 5-hydroxytryptamine. | J R Vane | Br J Pharmacol Chemother | 1957 | 13460242 | Yes |
3244 | 1149 | 1149.0 | 31.39 | 31.4 | Leishmaniasis. | B L Herwaldt | Lancet | 1999 | 10513726 | No |
3245 | 1149 | 1149.0 | 0.0 | 0.0 | The perceptron: a probabilistic model for information storage and organization in the brain. | F Rosenblatt | Psychol Rev | 1958 | 13602029 | Yes |
3246 | 2297 | 1148.5 | 51.74 | 25.9 | Shape-controlled synthesis of gold and silver nanoparticles. | Yugang Sun, Younan Xia | Science | 2002 | 12481134 | Yes |
3247 | 1148 | 1148.0 | 33.02 | 33.0 | Nature of Col E 1 plasmid replication in Escherichia coli in the presence of the chloramphenicol. | D B Clewell | J Bacteriol | 1972 | 4336693 | Yes |
3248 | 1148 | 1148.0 | 29.42 | 29.4 | The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. | R A Jain | Biomaterials | 2000 | 11055295 | No |
3249 | 1148 | 1148.0 | 24.73 | 24.7 | Serine protease mechanism and specificity. | Lizbeth Hedstrom | Chem Rev | 2002 | 12475199 | No |
3250 | 1148 | 1148.0 | 22.13 | 22.1 | Regulation of cadherin-mediated adhesion in morphogenesis. | Barry M Gumbiner | Nat Rev Mol Cell Biol | 2005 | 16025097 | No |
3251 | 1148 | 1148.0 | 27.96 | 28.0 | Nanoparticles, Proteins, and Nucleic Acids: Biotechnology Meets Materials Science. | Christof M Niemeyer | Angew Chem Int Ed Engl | 2001 | 29712109 | No |
3252 | 2295 | 1147.5 | 67.23 | 33.6 | Nitric oxide synthases in mammals. | R G Knowles, S Moncada | Biochem J | 1994 | 7510950 | No |
3253 | 1147 | 1147.0 | 31.94 | 31.9 | DNA topoisomerases. | M Gellert | Annu Rev Biochem | 1981 | 6267993 | No |
3254 | 1147 | 1147.0 | 0.0 | 0.0 | The powerful placebo. | H K Beecher | J Am Med Assoc | 1955 | 13271123 | Yes |
3255 | 1147 | 1147.0 | 41.18 | 41.2 | Postural orientation and equilibrium: what do we need to know about neural control of balance to prevent falls? | Fay B Horak | Age Ageing | 2006 | 16926210 | No |
3256 | 2294 | 1147.0 | 93.53 | 46.8 | Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation. | Ulrich M Zanger, Matthias Schwab | Pharmacol Ther | 2013 | 23333322 | No |
3257 | 2293 | 1146.5 | 66.75 | 33.4 | A rating scale for extrapyramidal side effects. | G M Simpson, J W Angus | Acta Psychiatr Scand Suppl | 1970 | 4917967 | Yes |
3258 | 2293 | 1146.5 | 50.55 | 25.3 | Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set. | N Sreerama, R W Woody | Anal Biochem | 2000 | 11112271 | Yes |
3259 | 2293 | 1146.5 | 50.38 | 25.2 | Esophageal cancer. | Peter C Enzinger, Robert J Mayer | N Engl J Med | 2003 | 14657432 | No |
3260 | 2293 | 1146.5 | 54.2 | 27.1 | Endometriosis. | Linda C Giudice, Lee C Kao | Lancet | 2004 | 15541453 | No |
3261 | 1146 | 1146.0 | 31.1 | 31.1 | Diseases of the mitochondrial DNA. | D C Wallace | Annu Rev Biochem | 1992 | 1497308 | No |
3262 | 1146 | 1146.0 | 39.2 | 39.2 | Estimation of the number of nucleotide substitutions when there are strong transition-transversion and G+C-content biases. | K Tamura | Mol Biol Evol | 1992 | 1630306 | Yes |
3263 | 1146 | 1146.0 | 48.28 | 48.3 | A spreading-activation theory of retrieval in sentence production. | G S Dell | Psychol Rev | 1986 | 3749399 | Yes |
3264 | 1146 | 1146.0 | 27.75 | 27.8 | Mode of action of membrane active antimicrobial peptides. | Yechiel Shai | Biopolymers | 2002 | 12491537 | No |
3265 | 4582 | 1145.5 | 110.95 | 27.7 | Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. | H Nielsen, J Engelbrecht, S Brunak, G von Heijne | Protein Eng | 1997 | 9051728 | Yes |
3266 | 2291 | 1145.5 | 67.32 | 33.7 | The capacity of visual working memory for features and conjunctions. | S J Luck, E K Vogel | Nature | 1997 | 9384378 | Yes |
3267 | 8016 | 1145.1 | 279.71 | 40.0 | Metagenomic biomarker discovery and explanation. | Nicola Segata, Jacques Izard, Levi Waldron, Dirk Gevers, Larisa Miropolsky, Wendy S Garrett, Curtis Huttenhower | Genome Biol | 2011 | 21702898 | Yes |
3268 | 2290 | 1145.0 | 109.02 | 54.5 | Research diagnostic criteria for temporomandibular disorders: review, criteria, examinations and specifications, critique. | S F Dworkin, L LeResche | J Craniomandib Disord | 1992 | 1298767 | No |
3269 | 2290 | 1145.0 | 68.38 | 34.2 | Multiple significance tests: the Bonferroni method. | J M Bland, D G Altman | BMJ | 1995 | 7833759 | Yes |
3270 | 1145 | 1145.0 | 7.07 | 7.1 | A New Serum Type System In Man--The Lp System. | K Berg | Acta Pathol Microbiol Scand | 1963 | 14064818 | Yes |
3271 | 1145 | 1145.0 | 24.08 | 24.1 | Version 1.2 of the Crystallography and NMR system. | Axel T Brunger | Nat Protoc | 2007 | 18007608 | Yes |
3272 | 3434 | 1144.7 | 91.59 | 30.5 | Matrix metalloproteinases: regulators of the tumor microenvironment. | Kai Kessenbrock, Vicki Plaks, Zena Werb | Cell | 2010 | 20371345 | No |
3273 | 3433 | 1144.3 | 95.61 | 31.9 | Regulation of cancer cell metabolism. | Rob A Cairns, Isaac S Harris, Tak W Mak | Nat Rev Cancer | 2011 | 21258394 | No |
3274 | 1144 | 1144.0 | 45.92 | 45.9 | Radioimmunological determination of human C-peptide in serum. | L G Heding | Diabetologia | 1975 | 1239396 | Yes |
3275 | 1144 | 1144.0 | 42.01 | 42.0 | Omega-3 fatty acids in health and disease and in growth and development. | A P Simopoulos | Am J Clin Nutr | 1991 | 1908631 | No |
3276 | 2288 | 1144.0 | 89.25 | 44.6 | A simple method to assess exercise behavior in the community. | G Godin, R J Shephard | Can J Appl Sport Sci | 1985 | 4053261 | Yes |
3277 | 1144 | 1144.0 | 32.98 | 33.0 | An improved fluorometric assay for DNA. | R T Hinegardner | Anal Biochem | 1971 | 5544593 | Yes |
3278 | 1144 | 1144.0 | 22.35 | 22.4 | Inferences, questions and possibilities in Toll-like receptor signalling. | Bruce Beutler | Nature | 2004 | 15241424 | No |
3279 | 2288 | 1144.0 | 61.11 | 30.6 | BODIPY dyes and their derivatives: syntheses and spectroscopic properties. | Aurore Loudet, Kevin Burgess | Chem Rev | 2007 | 17924696 | Yes |
3280 | 2288 | 1144.0 | 68.47 | 34.2 | Software survey: VOSviewer, a computer program for bibliometric mapping. | Nees Jan van Eck, Ludo Waltman | Scientometrics | 2010 | 20585380 | Yes |
3281 | 1144 | 1144.0 | 32.78 | 32.8 | Rethinking schizophrenia. | Thomas R Insel | Nature | 2010 | 21068826 | No |
3282 | 3431 | 1143.7 | 87.88 | 29.3 | The widespread regulation of microRNA biogenesis, function and decay. | Jacek Krol, Inga Loedige, Witold Filipowicz | Nat Rev Genet | 2010 | 20661255 | No |
3283 | 2287 | 1143.5 | 47.03 | 23.5 | Plant pathogens and integrated defence responses to infection. | J L Dangl, J D Jones | Nature | 2001 | 11459065 | No |
3284 | 2287 | 1143.5 | 67.85 | 33.9 | Type 2 diabetes as an inflammatory disease. | Marc Y Donath, Steven E Shoelson | Nat Rev Immunol | 2011 | 21233852 | No |
3285 | 3429 | 1143.0 | 107.89 | 36.0 | Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate. | G M Wahl, M Stern, G R Stark | Proc Natl Acad Sci U S A | 1979 | 291033 | Yes |
3286 | 1143 | 1143.0 | 33.25 | 33.2 | Animal mitochondrial DNA: structure and evolution. | D R Wolstenholme | Int Rev Cytol | 1992 | 1452431 | No |
3287 | 1143 | 1143.0 | 28.72 | 28.7 | Two-stage model of memory trace formation: a role for "noisy" brain states. | G Buzsáki | Neuroscience | 1989 | 2687720 | No |
3288 | 1143 | 1143.0 | 42.7 | 42.7 | Molecular aspects of ligand binding to serum albumin. | U Kragh-Hansen | Pharmacol Rev | 1981 | 7027277 | No |
3289 | 1143 | 1143.0 | 0.0 | 0.0 | Fertilizing capacity of spermatozoa deposited into the fallopian tubes. | M C Chang | Nature | 1951 | 14882325 | Yes |
3290 | 3428 | 1142.7 | 217.01 | 72.3 | Production, use, and fate of all plastics ever made. | Roland Geyer, Jenna R Jambeck, Kara Lavender Law | Sci Adv | 2017 | 28776036 | Yes |
3291 | 2285 | 1142.5 | 48.09 | 24.0 | Regulation of translation initiation in eukaryotes: mechanisms and biological targets. | Nahum Sonenberg, Alan G Hinnebusch | Cell | 2009 | 19239892 | No |
3292 | 6853 | 1142.2 | 198.17 | 33.0 | The unity and diversity of executive functions and their contributions to complex "Frontal Lobe" tasks: a latent variable analysis. | A Miyake, N P Friedman, M J Emerson, A H Witzki, A Howerter, T D Wager | Cogn Psychol | 2000 | 10945922 | Yes |
3293 | 1142 | 1142.0 | 16.6 | 16.6 | Biochemistry of dystrophic muscle. Mitochondrial succinate-tetrazolium reductase and adenosine triphosphatase. | R J Pennington | Biochem J | 1961 | 13734134 | Yes |
3294 | 1141 | 1141.0 | 33.34 | 33.3 | Reducing children's television viewing to prevent obesity: a randomized controlled trial. | T N Robinson | JAMA | 1999 | 10546696 | Yes |
3295 | 1141 | 1141.0 | 21.35 | 21.4 | Diffusion-in-gel methods for immunological analysis. II. | O Ouchterlony | Prog Allergy | 1962 | 14482809 | Yes |
3296 | 1141 | 1141.0 | 29.97 | 30.0 | A theory of magnitude: common cortical metrics of time, space and quantity. | Vincent Walsh | Trends Cogn Sci | 2003 | 14585444 | Yes |
3297 | 1141 | 1141.0 | 48.77 | 48.8 | The prevalence of DSM-IV attention-deficit/hyperactivity disorder: a meta-analytic review. | Erik G Willcutt | Neurotherapeutics | 2012 | 22976615 | No |
3298 | 1141 | 1141.0 | 57.45 | 57.5 | The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease. | Costantino Iadecola | Neuron | 2017 | 28957666 | No |
3299 | 2281 | 1140.5 | 44.44 | 22.2 | Homeobox genes and axial patterning. | W McGinnis, R Krumlauf | Cell | 1992 | 1346368 | No |
3300 | 1140 | 1140.0 | 40.41 | 40.4 | Neurotoxins that act on voltage-sensitive sodium channels in excitable membranes. | W A Catterall | Annu Rev Pharmacol Toxicol | 1980 | 6247957 | No |
3301 | 1140 | 1140.0 | 25.61 | 25.6 | Estimating absolute rates of molecular evolution and divergence times: a penalized likelihood approach. | Michael J Sanderson | Mol Biol Evol | 2002 | 11752195 | Yes |
3302 | 2280 | 1140.0 | 50.8 | 25.4 | microRNA functions. | Natascha Bushati, Stephen M Cohen | Annu Rev Cell Dev Biol | 2007 | 17506695 | No |
3303 | 1140 | 1140.0 | 25.4 | 25.4 | Next-generation DNA sequencing methods. | Elaine R Mardis | Annu Rev Genomics Hum Genet | 2008 | 18576944 | No |
3304 | 1139 | 1139.0 | 59.29 | 59.3 | A "rationalized" arcsine transform. | G A Studebaker | J Speech Hear Res | 1985 | 4046587 | Yes |
3305 | 2278 | 1139.0 | 60.22 | 30.1 | Analysis of gene control signals by DNA fusion and cloning in Escherichia coli. | M J Casadaban, S N Cohen | J Mol Biol | 1980 | 6997493 | Yes |
3306 | 1139 | 1139.0 | 21.13 | 21.1 | Regulation of phosphoinositide-specific phospholipase C. | S G Rhee | Annu Rev Biochem | 2001 | 11395409 | No |
3307 | 1139 | 1139.0 | 35.43 | 35.4 | Polybrominated diphenyl ethers in the environment and in people: a meta-analysis of concentrations. | Ronald A Hites | Environ Sci Technol | 2004 | 14998004 | Yes |
3308 | 2277 | 1138.5 | 53.74 | 26.9 | ZINC--a free database of commercially available compounds for virtual screening. | John J Irwin, Brian K Shoichet | J Chem Inf Model | 2005 | 15667143 | Yes |
3309 | 1138 | 1138.0 | 22.07 | 22.1 | Structure of chromatin. | R D Kornberg | Annu Rev Biochem | 1977 | 332067 | No |
3310 | 1138 | 1138.0 | 31.26 | 31.3 | Riddle of biofilm resistance. | K Lewis | Antimicrob Agents Chemother | 2001 | 11257008 | No |
3311 | 1138 | 1138.0 | 21.47 | 21.5 | The power and the promise of DNA methylation markers. | Peter W Laird | Nat Rev Cancer | 2003 | 12671664 | No |
3312 | 2276 | 1138.0 | 0.0 | 0.0 | Active transport of sodium as the source of electric current in the short-circuited isolated frog skin. | H H Ussing, K Zerahn | Acta Physiol Scand | 1951 | 14868510 | Yes |
3313 | 2275 | 1137.5 | 46.56 | 23.3 | Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. | G A Gonzalez, M R Montminy | Cell | 1989 | 2573431 | Yes |
3314 | 6823 | 1137.2 | 153.02 | 25.5 | Principal components analysis corrects for stratification in genome-wide association studies. | Alkes L Price, Nick J Patterson, Robert M Plenge, Michael E Weinblatt, Nancy A Shadick, David Reich | Nat Genet | 2006 | 16862161 | Yes |
3315 | 1137 | 1137.0 | 33.73 | 33.7 | Unstable angina. A classification. | E Braunwald | Circulation | 1989 | 2752565 | Yes |
3316 | 3411 | 1137.0 | 96.43 | 32.1 | Cytochemical identification of monocytes and granulocytes. | L T Yam, C Y Li, W H Crosby | Am J Clin Pathol | 1971 | 5549896 | Yes |
3317 | 1137 | 1137.0 | 49.95 | 50.0 | How neuroinflammation contributes to neurodegeneration. | Richard M Ransohoff | Science | 2016 | 27540165 | No |
3318 | 1136 | 1136.0 | 56.14 | 56.1 | The tension-stress effect on the genesis and growth of tissues. Part I. The influence of stability of fixation and soft-tissue preservation. | G A Ilizarov | Clin Orthop Relat Res | 1989 | 2910611 | Yes |
3319 | 2272 | 1136.0 | 66.79 | 33.4 | Health effects of fine particulate air pollution: lines that connect. | C Arden Pope, Douglas W Dockery | J Air Waste Manag Assoc | 2006 | 16805397 | No |
3320 | 3408 | 1136.0 | 144.67 | 48.2 | Principles of nanoparticle design for overcoming biological barriers to drug delivery. | Elvin Blanco, Haifa Shen, Mauro Ferrari | Nat Biotechnol | 2015 | 26348965 | Yes |
3321 | 3405 | 1135.0 | 97.09 | 32.4 | A sensitive and reliable locomotor rating scale for open field testing in rats. | D M Basso, M S Beattie, J C Bresnahan | J Neurotrauma | 1995 | 7783230 | Yes |
3322 | 1135 | 1135.0 | 20.15 | 20.1 | Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation. | Eric C Lai | Nat Genet | 2002 | 11896390 | Yes |
3323 | 1135 | 1135.0 | 21.87 | 21.9 | VEGF and the quest for tumour angiogenesis factors. | Napoleone Ferrara | Nat Rev Cancer | 2002 | 12360282 | No |
3324 | 1135 | 1135.0 | 26.68 | 26.7 | Transcriptional paradigms in mammalian mitochondrial biogenesis and function. | Richard C Scarpulla | Physiol Rev | 2008 | 18391175 | No |
3325 | 3405 | 1135.0 | 106.67 | 35.6 | Development and applications of CRISPR-Cas9 for genome engineering. | Patrick D Hsu, Eric S Lander, Feng Zhang | Cell | 2014 | 24906146 | No |
3326 | 1134 | 1134.0 | 30.76 | 30.8 | A toxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors. | Ron Hardman | Environ Health Perspect | 2006 | 16451849 | No |
3327 | 1134 | 1134.0 | 27.51 | 27.5 | Correlates of protection induced by vaccination. | Stanley A Plotkin | Clin Vaccine Immunol | 2010 | 20463105 | No |
3328 | 1134 | 1134.0 | 57.21 | 57.2 | Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review. | Dariush Mozaffarian | Circulation | 2016 | 26746178 | No |
3329 | 1133 | 1133.0 | 49.7 | 49.7 | Sixth gaddum memorial lecture, National Institute for Medical Research, Mill Hill, January 1977. Presynaptic receptors and their role in the regulation of transmitter release. | S Z Langer | Br J Pharmacol | 1977 | 20190 | No |
3330 | 2266 | 1133.0 | 77.34 | 38.7 | A simple index of Crohn's-disease activity. | R F Harvey, J M Bradshaw | Lancet | 1980 | 6102236 | Yes |
3331 | 1133 | 1133.0 | 22.11 | 22.1 | Regulation of transcription by MAP kinase cascades. | R Treisman | Curr Opin Cell Biol | 1996 | 8791420 | No |
3332 | 1133 | 1133.0 | 44.65 | 44.6 | Comments on 'KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease'. | Konrad M Andrassy | Kidney Int | 2013 | 23989362 | Yes |
3333 | 6795 | 1132.5 | 226.51 | 37.8 | The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. | Erik von Elm, Douglas G Altman, Matthias Egger, Stuart J Pocock, Peter C Gøtzsche, Jan P Vandenbroucke | J Clin Epidemiol | 2008 | 18313558 | Yes |
3334 | 1132 | 1132.0 | 42.21 | 42.2 | Second generation logarithmic estimates of single-pool variable volume Kt/V: an analysis of error. | J T Daugirdas | J Am Soc Nephrol | 1993 | 8305648 | Yes |
3335 | 1132 | 1132.0 | 26.13 | 26.1 | Allelic discrimination using fluorogenic probes and the 5' nuclease assay. | K J Livak | Genet Anal | 1999 | 10084106 | Yes |
3336 | 1132 | 1132.0 | 30.72 | 30.7 | Venous thrombosis: a multicausal disease. | F R Rosendaal | Lancet | 1999 | 10209995 | No |
3337 | 1132 | 1132.0 | 23.89 | 23.9 | Molecular imaging of cancer with positron emission tomography. | Sanjiv Sam Gambhir | Nat Rev Cancer | 2002 | 12209157 | No |
3338 | 2264 | 1132.0 | 49.05 | 24.5 | Deep tissue two-photon microscopy. | Fritjof Helmchen, Winfried Denk | Nat Methods | 2005 | 16299478 | No |
3339 | 1132 | 1132.0 | 0.0 | 0.0 | A microchemical reaction resulting in the staining of polysaccharide structures in fixed tissue preparations. | R D Hotchkiss | Arch Biochem | 1948 | 18921848 | Yes |
3340 | 1132 | 1132.0 | 50.34 | 50.3 | Canadian Diabetes Association 2013 clinical practice guidelines for the prevention and management of diabetes in Canada. Introduction. | Alice Y Y Cheng | Can J Diabetes | 2013 | 24070926 | No |
3341 | 1131 | 1131.0 | 20.28 | 20.3 | The development of neural stem cells. | S Temple | Nature | 2001 | 11689956 | No |
3342 | 1131 | 1131.0 | 23.12 | 23.1 | Understanding the odd science of aging. | Thomas B L Kirkwood | Cell | 2005 | 15734677 | No |
3343 | 1131 | 1131.0 | 30.8 | 30.8 | Stronger Brønsted acids. | Takahiko Akiyama | Chem Rev | 2007 | 17983247 | Yes |
3344 | 1130 | 1130.0 | 28.24 | 28.2 | Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture. | I J Fidler | Cancer Res | 1990 | 1698118 | Yes |
3345 | 3390 | 1130.0 | 72.31 | 24.1 | A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. | M Serrano, G J Hannon, D Beach | Nature | 1993 | 8259215 | Yes |
3346 | 1130 | 1130.0 | 26.47 | 26.5 | Aptamers: an emerging class of molecules that rival antibodies in diagnostics. | S D Jayasena | Clin Chem | 1999 | 10471678 | No |
3347 | 2260 | 1130.0 | 44.44 | 22.2 | Tumour-cell invasion and migration: diversity and escape mechanisms. | Peter Friedl, Katarina Wolf | Nat Rev Cancer | 2003 | 12724734 | No |
3348 | 1130 | 1130.0 | 30.56 | 30.6 | AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function. | D Grahame Hardie | Genes Dev | 2011 | 21937710 | No |
3349 | 2259 | 1129.5 | 90.7 | 45.4 | Rapid genetic identification and mapping of enzymatically amplified ribosomal DNA from several Cryptococcus species. | R Vilgalys, M Hester | J Bacteriol | 1990 | 2376561 | Yes |
3350 | 2259 | 1129.5 | 42.33 | 21.2 | The druggable genome. | Andrew L Hopkins, Colin R Groom | Nat Rev Drug Discov | 2002 | 12209152 | No |
3351 | 1129 | 1129.0 | 23.52 | 23.5 | Evolution of ageing. | T B Kirkwood | Nature | 1977 | 593350 | Yes |
3352 | 3387 | 1129.0 | 90.63 | 30.2 | Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. | R Schreck, P Rieber, P A Baeuerle | EMBO J | 1991 | 2065663 | Yes |
3353 | 1129 | 1129.0 | 28.55 | 28.6 | Stereochemical criteria for polypeptides and proteins. V. Conformation of a system of three linked peptide units. | C M Venkatachalam | Biopolymers | 1968 | 5685102 | Yes |
3354 | 1129 | 1129.0 | 38.27 | 38.3 | Selective attention and the organization of visual information. | J Duncan | J Exp Psychol Gen | 1984 | 6240521 | Yes |
3355 | 2258 | 1129.0 | 58.38 | 29.2 | Protein oxidation in aging, disease, and oxidative stress. | B S Berlett, E R Stadtman | J Biol Chem | 1997 | 9252331 | No |
3356 | 1129 | 1129.0 | 36.01 | 36.0 | Predictors of postpartum depression: an update. | C T Beck | Nurs Res | 2001 | 11570712 | Yes |
3357 | 1129 | 1129.0 | 30.21 | 30.2 | Disseminating innovations in health care. | Donald M Berwick | JAMA | 2003 | 12697800 | Yes |
3358 | 3387 | 1129.0 | 91.27 | 30.4 | Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. | Robert G Hart, Lesly A Pearce, Maria I Aguilar | Ann Intern Med | 2007 | 17577005 | Yes |
3359 | 2257 | 1128.5 | 51.38 | 25.7 | The Polycomb complex PRC2 and its mark in life. | Raphaël Margueron, Danny Reinberg | Nature | 2011 | 21248841 | No |
3360 | 1128 | 1128.0 | 38.52 | 38.5 | Radioimmunoassay: a method for human chorionic gonadotropin and human luteinizing hormone. | A R Midgley | Endocrinology | 1966 | 5950482 | Yes |
3361 | 1128 | 1128.0 | 30.23 | 30.2 | The chromosomal basis of human neoplasia. | J J Yunis | Science | 1983 | 6336310 | Yes |
3362 | 1128 | 1128.0 | 24.72 | 24.7 | r8s: inferring absolute rates of molecular evolution and divergence times in the absence of a molecular clock. | Michael J Sanderson | Bioinformatics | 2003 | 12538260 | Yes |
3363 | 1128 | 1128.0 | 0.0 | 0.0 | Micromethods for the study of proteins and antibodies. I. Procedure and general applications of hemagglutination and hemagglutination-inhibition reactions with tannic acid and protein-treated red blood cells. | A B Stavitsky | J Immunol | 1954 | 13163409 | Yes |
3364 | 2256 | 1128.0 | 20.91 | 10.5 | A Generalization Of The Retention Index System Including Linear Temperature Programmed Gas-Liquid Partition Chromatography. | H Vandendool, P D Kratz | J Chromatogr | 1963 | 14062605 | Yes |
3365 | 2256 | 1128.0 | 99.07 | 49.5 | The lifelong effects of early childhood adversity and toxic stress. | Jack P Shonkoff, Andrew S Garner | Pediatrics | 2012 | 22201156 | Yes |
3366 | 1128 | 1128.0 | 43.59 | 43.6 | Review of the key results from the Swedish Obese Subjects (SOS) trial - a prospective controlled intervention study of bariatric surgery. | L Sjöström | J Intern Med | 2013 | 23163728 | No |
3367 | 2255 | 1127.5 | 32.82 | 16.4 | Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases. | L M Siegel, K J Monty | Biochim Biophys Acta | 1966 | 5329026 | Yes |
3368 | 1127 | 1127.0 | 31.91 | 31.9 | Cholesterol and the cell membrane. | P L Yeagle | Biochim Biophys Acta | 1985 | 3904832 | No |
3369 | 1127 | 1127.0 | 14.81 | 14.8 | The nature and significance of platelet products in human plasma. | P Wolf | Br J Haematol | 1967 | 6025241 | Yes |
3370 | 1127 | 1127.0 | 42.55 | 42.5 | On the regulation and control of fibrinolysis. Edward Kowalski Memorial Lecture. | D Collen | Thromb Haemost | 1980 | 6450468 | No |
3371 | 1127 | 1127.0 | 23.95 | 23.9 | Fluorescence spectroscopy of single biomolecules. | S Weiss | Science | 1999 | 10073925 | No |
3372 | 2254 | 1127.0 | 68.76 | 34.4 | Self-management education: history, definition, outcomes, and mechanisms. | Kate R Lorig, Halsted Holman | Ann Behav Med | 2003 | 12867348 | No |
3373 | 1127 | 1127.0 | 31.79 | 31.8 | Neurophysiological and computational principles of cortical rhythms in cognition. | Xiao-Jing Wang | Physiol Rev | 2010 | 20664082 | No |
3374 | 2254 | 1127.0 | 73.17 | 36.6 | Long non-coding RNAs: new players in cell differentiation and development. | Alessandro Fatica, Irene Bozzoni | Nat Rev Genet | 2014 | 24296535 | No |
3375 | 11269 | 1126.9 | 444.46 | 44.4 | MrBayes 3.2: efficient Bayesian phylogenetic inference and model choice across a large model space. | Fredrik Ronquist, Maxim Teslenko, Paul van der Mark, Daniel L Ayres, Aaron Darling, Sebastian Höhna, Bret Larget, Liang Liu, Marc A Suchard, John P Huelsenbeck | Syst Biol | 2012 | 22357727 | Yes |
3376 | 2252 | 1126.0 | 75.47 | 37.7 | Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. | A E Czeizel, I Dudás | N Engl J Med | 1992 | 1307234 | Yes |
3377 | 1126 | 1126.0 | 23.63 | 23.6 | Mutator phenotype may be required for multistage carcinogenesis. | L A Loeb | Cancer Res | 1991 | 2039987 | No |
3378 | 1126 | 1126.0 | 28.58 | 28.6 | Intestinal epithelial cell surface membrane glycoprotein synthesis. I. An indicator of cellular differentiation. | M M Weiser | J Biol Chem | 1973 | 4698230 | Yes |
3379 | 1126 | 1126.0 | 24.95 | 24.9 | Possible role of flanking nucleotides in recognition of the AUG initiator codon by eukaryotic ribosomes. | M Kozak | Nucleic Acids Res | 1981 | 7301588 | Yes |
3380 | 2252 | 1126.0 | 60.46 | 30.2 | Mechanisms of biofilm resistance to antimicrobial agents. | T F Mah, G A O'Toole | Trends Microbiol | 2001 | 11166241 | No |
3381 | 1126 | 1126.0 | 20.59 | 20.6 | DNA methylation in cancer: too much, but also too little. | Melanie Ehrlich | Oncogene | 2002 | 12154403 | No |
3382 | 2252 | 1126.0 | 54.11 | 27.1 | ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis. | Benoît D'Autréaux, Michel B Toledano | Nat Rev Mol Cell Biol | 2007 | 17848967 | No |
3383 | 1126 | 1126.0 | 0.0 | 0.0 | Knee joint changes after meniscectomy. | T J Fairbank | J Bone Joint Surg Br | 1948 | 18894618 | Yes |
3384 | 1126 | 1126.0 | 0.0 | 0.0 | pA, a new scale for the measurement of drug antagonism. | H O Schild | Br J Pharmacol Chemother | 1947 | 20258355 | Yes |
3385 | 1125 | 1125.0 | 26.53 | 26.5 | Mechanisms of lipid peroxide formation in animal tissues. | E D Wills | Biochem J | 1966 | 5964963 | Yes |
3386 | 1125 | 1125.0 | 33.12 | 33.1 | Cell surface interactions with extracellular materials. | K M Yamada | Annu Rev Biochem | 1983 | 6351729 | No |
3387 | 2250 | 1125.0 | 55.02 | 27.5 | The protective effects of estrogen on the cardiovascular system. | M E Mendelsohn, R H Karas | N Engl J Med | 1999 | 10362825 | No |
3388 | 2250 | 1125.0 | 53.88 | 26.9 | Toxoplasmosis. | J G Montoya, O Liesenfeld | Lancet | 2004 | 15194258 | No |
3389 | 1125 | 1125.0 | 42.92 | 42.9 | Amyloid-β and tau: the trigger and bullet in Alzheimer disease pathogenesis. | George S Bloom | JAMA Neurol | 2014 | 24493463 | No |
3390 | 1125 | 1125.0 | 45.94 | 45.9 | The biology and function of exosomes in cancer. | Raghu Kalluri | J Clin Invest | 2016 | 27035812 | No |
3391 | 1124 | 1124.0 | 67.46 | 67.5 | Cytoprotection by prostaglandins. | A Robert | Gastroenterology | 1979 | 38173 | Yes |
3392 | 1124 | 1124.0 | 54.48 | 54.5 | Self-discrepancy: a theory relating self and affect. | E T Higgins | Psychol Rev | 1987 | 3615707 | Yes |
3393 | 1124 | 1124.0 | 23.04 | 23.0 | Differentiation and proliferation of hematopoietic stem cells. | M Ogawa | Blood | 1993 | 8499622 | No |
3394 | 2248 | 1124.0 | 59.13 | 29.6 | Oxidative stress, caloric restriction, and aging. | R S Sohal, R Weindruch | Science | 1996 | 8658196 | No |
3395 | 1124 | 1124.0 | 0.0 | 0.0 | The degree of masculine differentiation of obesities: a factor determining predisposition to diabetes, atherosclerosis, gout, and uric calculous disease. | J Vague | Am J Clin Nutr | 1956 | 13282851 | Yes |
3396 | 1124 | 1124.0 | 17.25 | 17.2 | Inherited Antithrombin Deficiency Causing Thrombophilia. | O Egeberg | Thromb Diath Haemorrh | 1965 | 14347873 | Yes |
3397 | 2248 | 1124.0 | 49.02 | 24.5 | Regeneration beyond the glial scar. | Jerry Silver, Jared H Miller | Nat Rev Neurosci | 2004 | 14735117 | No |
3398 | 2248 | 1124.0 | 68.41 | 34.2 | Mitochondrial fission, fusion, and stress. | Richard J Youle, Alexander M van der Bliek | Science | 2012 | 22936770 | No |
3399 | 1123 | 1123.0 | 23.44 | 23.4 | ALSCRIPT: a tool to format multiple sequence alignments. | G J Barton | Protein Eng | 1993 | 8433969 | Yes |
3400 | 1123 | 1123.0 | 25.42 | 25.4 | The columnar organization of the neocortex. | V B Mountcastle | Brain | 1997 | 9153131 | No |
3401 | 2246 | 1123.0 | 88.55 | 44.3 | Statistical methods for assessing measurement error (reliability) in variables relevant to sports medicine. | G Atkinson, A M Nevill | Sports Med | 1998 | 9820922 | No |
3402 | 1123 | 1123.0 | 45.95 | 46.0 | The PEDro scale is a valid measure of the methodological quality of clinical trials: a demographic study. | Natalie A de Morton | Aust J Physiother | 2009 | 19463084 | Yes |
3403 | 1123 | 1123.0 | 70.83 | 70.8 | Information bias in health research: definition, pitfalls, and adjustment methods. | Alaa Althubaiti | J Multidiscip Healthc | 2016 | 27217764 | No |
3404 | 4489 | 1122.2 | 103.28 | 25.8 | SCOP: a structural classification of proteins database for the investigation of sequences and structures. | A G Murzin, S E Brenner, T Hubbard, C Chothia | J Mol Biol | 1995 | 7723011 | Yes |
3405 | 1122 | 1122.0 | 27.7 | 27.7 | Formation and function of the myofibroblast during tissue repair. | Boris Hinz | J Invest Dermatol | 2007 | 17299435 | No |
3406 | 2244 | 1122.0 | 50.03 | 25.0 | Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. | William G Kaelin, Peter J Ratcliffe | Mol Cell | 2008 | 18498744 | No |
3407 | 1122 | 1122.0 | 64.32 | 64.3 | Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features and Rome IV. | Douglas A Drossman | Gastroenterology | 2016 | 27144617 | Yes |
3408 | 4486 | 1121.5 | 110.19 | 27.5 | Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. | Michael D Greicius, Ben Krasnow, Allan L Reiss, Vinod Menon | Proc Natl Acad Sci U S A | 2003 | 12506194 | Yes |
3409 | 2243 | 1121.5 | 50.97 | 25.5 | Next-generation DNA sequencing. | Jay Shendure, Hanlee Ji | Nat Biotechnol | 2008 | 18846087 | Yes |
3410 | 1121 | 1121.0 | 22.05 | 22.1 | Cytokine receptor signalling. | J N Ihle | Nature | 1995 | 7566171 | No |
3411 | 1121 | 1121.0 | 32.62 | 32.6 | Modeling tracer kinetics in dynamic Gd-DTPA MR imaging. | P S Tofts | J Magn Reson Imaging | 1997 | 9039598 | No |
3412 | 1121 | 1121.0 | 29.59 | 29.6 | Time is brain--quantified. | Jeffrey L Saver | Stroke | 2006 | 16339467 | Yes |
3413 | 2241 | 1120.5 | 59.16 | 29.6 | Fitness effects on the cognitive function of older adults: a meta-analytic study. | Stanley Colcombe, Arthur F Kramer | Psychol Sci | 2003 | 12661673 | Yes |
3414 | 1120 | 1120.0 | 34.45 | 34.5 | Prostate specific antigen: a critical assessment of the most useful tumor marker for adenocarcinoma of the prostate. | J E Oesterling | J Urol | 1991 | 1707989 | No |
3415 | 2240 | 1120.0 | 48.91 | 24.5 | Prediction of protein secondary structure at better than 70% accuracy. | B Rost, C Sander | J Mol Biol | 1993 | 8345525 | Yes |
3416 | 2240 | 1120.0 | 51.12 | 25.6 | Modes of resistance to anti-angiogenic therapy. | Gabriele Bergers, Douglas Hanahan | Nat Rev Cancer | 2008 | 18650835 | No |
3417 | 2240 | 1120.0 | 64.51 | 32.3 | Strategies in the design of nanoparticles for therapeutic applications. | Robby A Petros, Joseph M DeSimone | Nat Rev Drug Discov | 2010 | 20616808 | No |
3418 | 4476 | 1119.0 | 145.07 | 36.3 | The cholinergic hypothesis of geriatric memory dysfunction. | R T Bartus, R L Dean, B Beer, A S Lippa | Science | 1982 | 7046051 | No |
3419 | 2237 | 1118.5 | 50.15 | 25.1 | Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission. | P van den Driessche, James Watmough | Math Biosci | 2002 | 12387915 | Yes |
3420 | 1118 | 1118.0 | 51.51 | 51.5 | Resilience in the face of adversity. Protective factors and resistance to psychiatric disorder. | M Rutter | Br J Psychiatry | 1985 | 3830321 | Yes |
3421 | 1118 | 1118.0 | 0.0 | 0.0 | Immunogenetic Consequences Of Vascular Anastomoses Between Bovine Twins. | R D Owen | Science | 1945 | 17755278 | Yes |
3422 | 1118 | 1118.0 | 57.01 | 57.0 | Patient reported outcome measures could help transform healthcare. | Nick Black | BMJ | 2013 | 23358487 | Yes |
3423 | 4470 | 1117.5 | 107.87 | 27.0 | C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. | P M Ridker, C H Hennekens, J E Buring, N Rifai | N Engl J Med | 2000 | 10733371 | Yes |
3424 | 5586 | 1117.2 | 110.87 | 22.2 | Electrostatics of nanosystems: application to microtubules and the ribosome. | N A Baker, D Sept, S Joseph, M J Holst, J A McCammon | Proc Natl Acad Sci U S A | 2001 | 11517324 | Yes |
3425 | 1117 | 1117.0 | 23.52 | 23.5 | Molecular cloning and expression of glycogen synthase kinase-3/factor A. | J R Woodgett | EMBO J | 1990 | 2164470 | Yes |
3426 | 1117 | 1117.0 | 51.47 | 51.5 | Analysis of Fickian and non-Fickian drug release from polymers. | N A Peppas | Pharm Acta Helv | 1985 | 4011621 | Yes |
3427 | 3350 | 1116.7 | 119.39 | 39.8 | Neighborhoods and violent crime: a multilevel study of collective efficacy. | R J Sampson, S W Raudenbush, F Earls | Science | 1997 | 9252316 | Yes |
3428 | 6699 | 1116.5 | 153.4 | 25.6 | Staging of brain pathology related to sporadic Parkinson's disease. | Heiko Braak, Kelly Del Tredici, Udo Rüb, Rob A I de Vos, Ernst N H Jansen Steur, Eva Braak | Neurobiol Aging | 2003 | 12498954 | Yes |
3429 | 1116 | 1116.0 | 23.81 | 23.8 | Complement. Second of two parts. | M J Walport | N Engl J Med | 2001 | 11297706 | No |
3430 | 2231 | 1115.5 | 45.16 | 22.6 | A survey of telomerase activity in human cancer. | J W Shay, S Bacchetti | Eur J Cancer | 1997 | 9282118 | No |
3431 | 2231 | 1115.5 | 72.95 | 36.5 | Microdroplet Assay Of Human Serum Cytotoxins. | P I Terasaki, J D Mcclelland | Nature | 1964 | 14248725 | Yes |
3432 | 3346 | 1115.3 | 89.27 | 29.8 | A nonparametric method for automatic correction of intensity nonuniformity in MRI data. | J G Sled, A P Zijdenbos, A C Evans | IEEE Trans Med Imaging | 1998 | 9617910 | Yes |
3433 | 1115 | 1115.0 | 36.96 | 37.0 | Chemoprevention of cancer. | L W Wattenberg | Cancer Res | 1985 | 3880665 | No |
3434 | 1115 | 1115.0 | 26.54 | 26.5 | Molecular drive: a cohesive mode of species evolution. | G Dover | Nature | 1982 | 7110332 | Yes |
3435 | 1115 | 1115.0 | 25.63 | 25.6 | Large Amplitude Elastic Motions in Proteins from a Single-Parameter, Atomic Analysis. | M M Tirion | Phys Rev Lett | 1996 | 10063201 | Yes |
3436 | 1115 | 1115.0 | 25.27 | 25.3 | The impact of next-generation sequencing technology on genetics. | Elaine R Mardis | Trends Genet | 2008 | 18262675 | No |
3437 | 2229 | 1114.5 | 69.88 | 34.9 | Excitatory amino acid transmitters. | J C Watkins, R H Evans | Annu Rev Pharmacol Toxicol | 1981 | 6112965 | No |
3438 | 2229 | 1114.5 | 49.64 | 24.8 | Obesity and insulin resistance. | B B Kahn, J S Flier | J Clin Invest | 2000 | 10953022 | No |
3439 | 2229 | 1114.5 | 60.81 | 30.4 | Mechanisms of mitophagy. | Richard J Youle, Derek P Narendra | Nat Rev Mol Cell Biol | 2011 | 21179058 | No |
3440 | 1114 | 1114.0 | 34.66 | 34.7 | Protein damage and degradation by oxygen radicals. I. general aspects. | K J Davies | J Biol Chem | 1987 | 3036875 | Yes |
3441 | 2228 | 1114.0 | 50.11 | 25.1 | Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms. | R J Britten, D E Kohne | Science | 1968 | 4874239 | Yes |
3442 | 1114 | 1114.0 | 31.45 | 31.4 | Studies on histones. 7. Preparative methods for histone fractions from calf thymus. | E W Johns | Biochem J | 1964 | 5840387 | Yes |
3443 | 1114 | 1114.0 | 20.64 | 20.6 | The ubiquitin-proteasome pathway: on protein death and cell life. | A Ciechanover | EMBO J | 1998 | 9857172 | No |
3444 | 1114 | 1114.0 | 27.73 | 27.7 | Immortal time bias in pharmaco-epidemiology. | Samy Suissa | Am J Epidemiol | 2008 | 18056625 | No |
3445 | 2227 | 1113.5 | 34.45 | 17.2 | Construction of phylogenetic trees. | W M Fitch, E Margoliash | Science | 1967 | 5334057 | No |
3446 | 1113 | 1113.0 | 28.47 | 28.5 | Linkage strategies for genetically complex traits. I. Multilocus models. | N Risch | Am J Hum Genet | 1990 | 2301392 | Yes |
3447 | 1113 | 1113.0 | 28.03 | 28.0 | Sex-hormone-binding globulin. | D C Anderson | Clin Endocrinol (Oxf) | 1974 | 4134992 | No |
3448 | 1113 | 1113.0 | 19.87 | 19.9 | NFAT proteins: key regulators of T-cell development and function. | Fernando Macian | Nat Rev Immunol | 2005 | 15928679 | No |
3449 | 1113 | 1113.0 | 35.71 | 35.7 | Social support and health: a review of physiological processes potentially underlying links to disease outcomes. | Bert N Uchino | J Behav Med | 2006 | 16758315 | No |
3450 | 11129 | 1112.9 | 253.37 | 25.3 | Scalable molecular dynamics with NAMD. | James C Phillips, Rosemary Braun, Wei Wang, James Gumbart, Emad Tajkhorshid, Elizabeth Villa, Christophe Chipot, Robert D Skeel, Laxmikant Kalé, Klaus Schulten | J Comput Chem | 2005 | 16222654 | Yes |
3451 | 1112 | 1112.0 | 39.35 | 39.4 | Epidemiological synergy. Interrelationships between human immunodeficiency virus infection and other sexually transmitted diseases. | J N Wasserheit | Sex Transm Dis | 1992 | 1595015 | No |
3452 | 2224 | 1112.0 | 59.0 | 29.5 | Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. | R A Ignotz, J Massagué | J Biol Chem | 1986 | 3456347 | Yes |
3453 | 2224 | 1112.0 | 44.83 | 22.4 | RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. | M B Shapiro, P Senapathy | Nucleic Acids Res | 1987 | 3658675 | Yes |
3454 | 1112 | 1112.0 | 29.34 | 29.3 | Comprehensive observational assessment: Ia. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse. | S Irwin | Psychopharmacologia | 1968 | 5679627 | Yes |
3455 | 1112 | 1112.0 | 32.92 | 32.9 | Plasmid complements of Streptococcus lactis NCDO 712 and other lactic streptococci after protoplast-induced curing. | M J Gasson | J Bacteriol | 1983 | 6403500 | Yes |
3456 | 1112 | 1112.0 | 37.44 | 37.4 | A review of psychological risk factors in back and neck pain. | S J Linton | Spine (Phila Pa 1976) | 2000 | 10788861 | No |
3457 | 4448 | 1112.0 | 116.9 | 29.2 | Prevalence and trends in obesity among US adults, 1999-2000. | Katherine M Flegal, Margaret D Carroll, Cynthia L Ogden, Clifford L Johnson | JAMA | 2002 | 12365955 | Yes |
3458 | 1112 | 1112.0 | 0.0 | 0.0 | A cytoarchitectonic atlas of the spinal cord in the cat. | B Rexed | J Comp Neurol | 1954 | 13163236 | Yes |
3459 | 2224 | 1112.0 | 0.0 | 0.0 | Localization of antigen in tissue cells; improvements in a method for the detection of antigen by means of fluorescent antibody. | A H Coons, M H Kaplan | J Exp Med | 1950 | 15395569 | Yes |
3460 | 1112 | 1112.0 | 26.19 | 26.2 | Complementing the genome with an "exposome": the outstanding challenge of environmental exposure measurement in molecular epidemiology. | Christopher Paul Wild | Cancer Epidemiol Biomarkers Prev | 2005 | 16103423 | No |
3461 | 1112 | 1112.0 | 0.0 | 0.0 | The Stability of Broken Ends of Chromosomes in Zea Mays. | B McClintock | Genetics | 1941 | 17247004 | Yes |
3462 | 2224 | 1112.0 | 63.28 | 31.6 | Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. | Patrick S Ward, Craig B Thompson | Cancer Cell | 2012 | 22439925 | No |
3463 | 1111 | 1111.0 | 31.87 | 31.9 | The role of rumination in depressive disorders and mixed anxiety/depressive symptoms. | S Nolen-Hoeksema | J Abnorm Psychol | 2000 | 11016119 | Yes |
3464 | 1111 | 1111.0 | 25.77 | 25.8 | Anatomy and regulation of the central melanocortin system. | Roger D Cone | Nat Neurosci | 2005 | 15856065 | No |
3465 | 1111 | 1111.0 | 25.21 | 25.2 | Viruses in the sea. | Curtis A Suttle | Nature | 2005 | 16163346 | No |
3466 | 1111 | 1111.0 | 0.0 | 0.0 | Comparing individual means in the analysis of variance. | J W Tukey | Biometrics | 1949 | 18151955 | Yes |
3467 | 6666 | 1111.0 | 252.15 | 42.0 | Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science. | Laura J Damschroder, David C Aron, Rosalind E Keith, Susan R Kirsh, Jeffery A Alexander, Julie C Lowery | Implement Sci | 2009 | 19664226 | Yes |
3468 | 3332 | 1110.7 | 80.75 | 26.9 | Mechanisms linking obesity to insulin resistance and type 2 diabetes. | Steven E Kahn, Rebecca L Hull, Kristina M Utzschneider | Nature | 2006 | 17167471 | No |
3469 | 2221 | 1110.5 | 45.59 | 22.8 | Genomic control for association studies. | B Devlin, K Roeder | Biometrics | 1999 | 11315092 | Yes |
3470 | 1110 | 1110.0 | 30.83 | 30.8 | On the utility of P3 amplitude as a measure of processing capacity. | A Kok | Psychophysiology | 2001 | 11352145 | No |
3471 | 2219 | 1109.5 | 54.09 | 27.0 | Adipocytokines: mediators linking adipose tissue, inflammation and immunity. | Herbert Tilg, Alexander R Moschen | Nat Rev Immunol | 2006 | 16998510 | No |
3472 | 4437 | 1109.2 | 24.26 | 6.1 | The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. | P J Randle, P B Garland, C N Hales, E A Newsholme | Lancet | 1963 | 13990765 | Yes |
3473 | 3327 | 1109.0 | 113.64 | 37.9 | Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides. | M Hamberg, J Svensson, B Samuelsson | Proc Natl Acad Sci U S A | 1975 | 1059088 | Yes |
3474 | 2218 | 1109.0 | 51.99 | 26.0 | Cellular uptake of the tat protein from human immunodeficiency virus. | A D Frankel, C O Pabo | Cell | 1988 | 2849510 | Yes |
3475 | 1109 | 1109.0 | 24.56 | 24.6 | The molecular biology of leukocyte chemoattractant receptors. | P M Murphy | Annu Rev Immunol | 1994 | 8011292 | No |
3476 | 1109 | 1109.0 | 33.66 | 33.7 | Inferring microstructural features and the physiological state of tissues from diffusion-weighted images. | P J Basser | NMR Biomed | 1995 | 8739270 | No |
3477 | 2216 | 1108.0 | 71.42 | 35.7 | Wine, alcohol, platelets, and the French paradox for coronary heart disease. | S Renaud, M de Lorgeril | Lancet | 1992 | 1351198 | Yes |
3478 | 2216 | 1108.0 | 90.56 | 45.3 | Tripartite model of anxiety and depression: psychometric evidence and taxonomic implications. | L A Clark, D Watson | J Abnorm Psychol | 1991 | 1918611 | No |
3479 | 1108 | 1108.0 | 24.15 | 24.1 | Toward self-organization and complex matter. | Jean-Marie Lehn | Science | 2002 | 11923524 | Yes |
3480 | 1108 | 1108.0 | 21.06 | 21.1 | Focal adhesion kinase: the first ten years. | J Thomas Parsons | J Cell Sci | 2003 | 12640026 | No |
3481 | 1108 | 1108.0 | 44.16 | 44.2 | Myeloid-Derived Suppressor Cells. | Dmitry I Gabrilovich | Cancer Immunol Res | 2017 | 28052991 | No |
3482 | 2215 | 1107.5 | 47.45 | 23.7 | Roles of CHOP/GADD153 in endoplasmic reticulum stress. | S Oyadomari, M Mori | Cell Death Differ | 2004 | 14685163 | No |
3483 | 1107 | 1107.0 | 27.35 | 27.4 | Avidin. | N M Green | Adv Protein Chem | 1975 | 237414 | Yes |
3484 | 1107 | 1107.0 | 22.28 | 22.3 | Primary response genes induced by growth factors and tumor promoters. | H R Herschman | Annu Rev Biochem | 1991 | 1883198 | No |
3485 | 1107 | 1107.0 | 26.17 | 26.2 | Cells in stress: transcriptional activation of heat shock genes. | R I Morimoto | Science | 1993 | 8451637 | No |
3486 | 2214 | 1107.0 | 59.99 | 30.0 | Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis. | J A Sterne, M Egger | J Clin Epidemiol | 2001 | 11576817 | Yes |
3487 | 1107 | 1107.0 | 26.11 | 26.1 | Differential projections of the infralimbic and prelimbic cortex in the rat. | Robert P Vertes | Synapse | 2004 | 14579424 | Yes |
3488 | 5531 | 1106.2 | 234.05 | 46.8 | Integrating single-cell transcriptomic data across different conditions, technologies, and species. | Andrew Butler, Paul Hoffman, Peter Smibert, Efthymia Papalexi, Rahul Satija | Nat Biotechnol | 2018 | 29608179 | Yes |
3489 | 1106 | 1106.0 | 23.27 | 23.3 | A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor. | J Milbrandt | Science | 1987 | 3672127 | Yes |
3490 | 2212 | 1106.0 | 49.31 | 24.7 | Synaptic activity and the construction of cortical circuits. | L C Katz, C J Shatz | Science | 1996 | 8895456 | No |
3491 | 1106 | 1106.0 | 40.18 | 40.2 | Relativistic electronic-structure calculations employing a two-component no-pair formalism with external-field projection operators. | B A Hess | Phys Rev A Gen Phys | 1986 | 9897114 | Yes |
3492 | 1106 | 1106.0 | 26.36 | 26.4 | Quantification of beta-sheet amyloid fibril structures with thioflavin T. | H LeVine | Methods Enzymol | 1999 | 10507030 | Yes |
3493 | 1106 | 1106.0 | 29.02 | 29.0 | Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity. | F P Guengerich | Chem Res Toxicol | 2001 | 11409933 | No |
3494 | 1106 | 1106.0 | 23.6 | 23.6 | VEGF as a key mediator of angiogenesis in cancer. | Peter Carmeliet | Oncology | 2005 | 16301830 | No |
3495 | 2211 | 1105.5 | 70.76 | 35.4 | Mechanisms of fibrosis: therapeutic translation for fibrotic disease. | Thomas A Wynn, Thirumalai R Ramalingam | Nat Med | 2012 | 22772564 | No |
3496 | 3316 | 1105.3 | 66.03 | 22.0 | SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. | Jay D Horton, Joseph L Goldstein, Michael S Brown | J Clin Invest | 2002 | 11994399 | No |
3497 | 1105 | 1105.0 | 27.17 | 27.2 | The synthesis of complex carbohydrates by multiglycosyltransferase systems and their potential function in intercellular adhesion. | S Roseman | Chem Phys Lipids | 1970 | 5476326 | Yes |
3498 | 1105 | 1105.0 | 24.44 | 24.4 | Lithium batteries and cathode materials. | M Stanley Whittingham | Chem Rev | 2004 | 15669156 | Yes |
3499 | 3314 | 1104.7 | 91.85 | 30.6 | Spirometric reference values from a sample of the general U.S. population. | J L Hankinson, J R Odencrantz, K B Fedan | Am J Respir Crit Care Med | 1999 | 9872837 | Yes |
3500 | 2209 | 1104.5 | 82.3 | 41.1 | Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes. | I B Wilson, P D Cleary | JAMA | 1995 | 7996652 | Yes |
3501 | 1104 | 1104.0 | 21.31 | 21.3 | Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. | A S Baldwin | J Clin Invest | 2001 | 11160144 | No |
3502 | 1104 | 1104.0 | 32.68 | 32.7 | Cognitive and affective development in adolescence. | Laurence Steinberg | Trends Cogn Sci | 2005 | 15668099 | No |
3503 | 1104 | 1104.0 | 22.03 | 22.0 | Models, mechanisms and clinical evidence for cancer dormancy. | Julio A Aguirre-Ghiso | Nat Rev Cancer | 2007 | 17957189 | No |
3504 | 2207 | 1103.5 | 0.0 | 0.0 | Cortisone in ulcerative colitis; final report on a therapeutic trial. | S C Truelove, L J Witts | Br Med J | 1955 | 13260656 | Yes |
3505 | 2207 | 1103.5 | 52.66 | 26.3 | Reducing the dimensionality of data with neural networks. | G E Hinton, R R Salakhutdinov | Science | 2006 | 16873662 | Yes |
3506 | 2207 | 1103.5 | 65.27 | 32.6 | Chronic hepatitis B: update 2009. | Anna S F Lok, Brian J McMahon | Hepatology | 2009 | 19714720 | Yes |
3507 | 2207 | 1103.5 | 67.15 | 33.6 | Reactive oxygen species, cellular redox systems, and apoptosis. | Magdalena L Circu, Tak Yee Aw | Free Radic Biol Med | 2010 | 20045723 | No |
3508 | 2206 | 1103.0 | 27.69 | 13.8 | Demonstration Of Tumor-Specific Antigens In Human Colonic Carcinomata By Immunological Tolerance And Absorption Techniques. | P Gold, S O Freedman | J Exp Med | 1965 | 14270243 | Yes |
3509 | 1103 | 1103.0 | 25.7 | 25.7 | Solid-state nanopores. | Cees Dekker | Nat Nanotechnol | 2007 | 18654264 | No |
3510 | 3308 | 1102.7 | 94.59 | 31.5 | Interpretation of changes in health-related quality of life: the remarkable universality of half a standard deviation. | Geoffrey R Norman, Jeff A Sloan, Kathleen W Wyrwich | Med Care | 2003 | 12719681 | No |
3511 | 2205 | 1102.5 | 58.1 | 29.1 | Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance. | I Chopra, M Roberts | Microbiol Mol Biol Rev | 2001 | 11381101 | Yes |
3512 | 6614 | 1102.3 | 173.01 | 28.8 | Prediction of coronary heart disease using risk factor categories. | P W Wilson, R B D'Agostino, D Levy, A M Belanger, H Silbershatz, W B Kannel | Circulation | 1998 | 9603539 | Yes |
3513 | 1102 | 1102.0 | 29.97 | 30.0 | Testicular biopsy score count--a method for registration of spermatogenesis in human testes: normal values and results in 335 hypogonadal males. | S G Johnsen | Hormones | 1970 | 5527187 | Yes |
3514 | 1102 | 1102.0 | 42.38 | 42.4 | The role of endothelium in the responses of vascular smooth muscle to drugs. | R F Furchgott | Annu Rev Pharmacol Toxicol | 1984 | 6203480 | No |
3515 | 1102 | 1102.0 | 27.35 | 27.4 | The Trk family of neurotrophin receptors. | M Barbacid | J Neurobiol | 1994 | 7852993 | No |
3516 | 4408 | 1102.0 | 148.92 | 37.2 | Prevalence and trends in obesity among US adults, 1999-2008. | Katherine M Flegal, Margaret D Carroll, Cynthia L Ogden, Lester R Curtin | JAMA | 2010 | 20071471 | Yes |
3517 | 1102 | 1102.0 | 37.52 | 37.5 | Globalization of diabetes: the role of diet, lifestyle, and genes. | Frank B Hu | Diabetes Care | 2011 | 21617109 | No |
3518 | 2203 | 1101.5 | 49.86 | 24.9 | A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. | J N Cohn, G Tognoni | N Engl J Med | 2001 | 11759645 | Yes |
3519 | 1101 | 1101.0 | 39.63 | 39.6 | Methods for dealing with reaction time outliers. | R Ratcliff | Psychol Bull | 1993 | 8272468 | Yes |
3520 | 1101 | 1101.0 | 28.18 | 28.2 | Neuropathology of Parkinson's disease. | L S Forno | J Neuropathol Exp Neurol | 1996 | 8786384 | No |
3521 | 1101 | 1101.0 | 24.6 | 24.6 | Current concepts of the pathogenesis of the acute coronary syndromes. | P Libby | Circulation | 2001 | 11457759 | No |
3522 | 2202 | 1101.0 | 63.56 | 31.8 | Relaxing the rule of ten events per variable in logistic and Cox regression. | Eric Vittinghoff, Charles E McCulloch | Am J Epidemiol | 2007 | 17182981 | Yes |
3523 | 2202 | 1101.0 | 50.93 | 25.5 | The host defense of Drosophila melanogaster. | Bruno Lemaitre, Jules Hoffmann | Annu Rev Immunol | 2007 | 17201680 | No |
3524 | 1101 | 1101.0 | 0.0 | 0.0 | Quantitative Determination of Carbohydrates With Dreywood's Anthrone Reagent. | D L Morris | Science | 1948 | 17814729 | Yes |
3525 | 2201 | 1100.5 | 38.27 | 19.1 | A synthetic oscillatory network of transcriptional regulators. | M B Elowitz, S Leibler | Nature | 2000 | 10659856 | Yes |
3526 | 1100 | 1100.0 | 50.99 | 51.0 | Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase. | Y Kono | Arch Biochem Biophys | 1978 | 24422 | Yes |
3527 | 1100 | 1100.0 | 23.02 | 23.0 | T-lymphocyte recognition of antigen in association with gene products of the major histocompatibility complex. | R H Schwartz | Annu Rev Immunol | 1985 | 2415139 | No |
3528 | 1100 | 1100.0 | 29.92 | 29.9 | Aging, energy, and oxidative stress in neurodegenerative diseases. | M F Beal | Ann Neurol | 1995 | 7668820 | No |
3529 | 1100 | 1100.0 | 22.41 | 22.4 | Osmotic stress signaling and osmoadaptation in yeasts. | Stefan Hohmann | Microbiol Mol Biol Rev | 2002 | 12040128 | No |
3530 | 1100 | 1100.0 | 22.82 | 22.8 | Membrane recognition by phospholipid-binding domains. | Mark A Lemmon | Nat Rev Mol Cell Biol | 2008 | 18216767 | No |
3531 | 2199 | 1099.5 | 63.52 | 31.8 | The acute phase response. | H Baumann, J Gauldie | Immunol Today | 1994 | 7512342 | No |
3532 | 2198 | 1099.0 | 51.78 | 25.9 | T antigen is bound to a host protein in SV40-transformed cells. | D P Lane, L V Crawford | Nature | 1979 | 218111 | Yes |
3533 | 1099 | 1099.0 | 33.39 | 33.4 | Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. | D L Coleman | Diabetologia | 1978 | 350680 | No |
3534 | 2198 | 1099.0 | 49.07 | 24.5 | Cell cycle control and cancer. | L H Hartwell, M B Kastan | Science | 1994 | 7997877 | No |
3535 | 1099 | 1099.0 | 22.98 | 23.0 | Phenotypic plasticity and the epigenetics of human disease. | Andrew P Feinberg | Nature | 2007 | 17522677 | No |
3536 | 1099 | 1099.0 | 39.87 | 39.9 | Visual attention: the past 25 years. | Marisa Carrasco | Vision Res | 2011 | 21549742 | No |
3537 | 2197 | 1098.5 | 85.83 | 42.9 | Long Noncoding RNAs in Cancer Pathways. | Adam M Schmitt, Howard Y Chang | Cancer Cell | 2016 | 27070700 | No |
3538 | 1098 | 1098.0 | 19.64 | 19.6 | Time-dependent processes in memory storage. | J L McGaugh | Science | 1966 | 5917768 | Yes |
3539 | 2196 | 1098.0 | 45.45 | 22.7 | p53: puzzle and paradigm. | L J Ko, C Prives | Genes Dev | 1996 | 8654922 | No |
3540 | 1098 | 1098.0 | 36.09 | 36.1 | Socioeconomic disadvantage and child development. | V C McLoyd | Am Psychol | 1998 | 9491747 | No |
3541 | 1098 | 1098.0 | 0.0 | 0.0 | Cleavage of the haem-protein link by acid methylethylketone. | F W Teale | Biochim Biophys Acta | 1959 | 13837237 | Yes |
3542 | 1098 | 1098.0 | 45.14 | 45.1 | How does sexual minority stigma "get under the skin"? A psychological mediation framework. | Mark L Hatzenbuehler | Psychol Bull | 2009 | 19702379 | No |
3543 | 7684 | 1097.7 | 239.04 | 34.1 | Toxicity and response criteria of the Eastern Cooperative Oncology Group. | M M Oken, R H Creech, D C Tormey, J Horton, T E Davis, E T McFadden, P P Carbone | Am J Clin Oncol | 1982 | 7165009 | Yes |
3544 | 2195 | 1097.5 | 70.25 | 35.1 | Central sensitization: a generator of pain hypersensitivity by central neural plasticity. | Alban Latremoliere, Clifford J Woolf | J Pain | 2009 | 19712899 | No |
3545 | 2195 | 1097.5 | 94.98 | 47.5 | Moving towards best practice when using inverse probability of treatment weighting (IPTW) using the propensity score to estimate causal treatment effects in observational studies. | Peter C Austin, Elizabeth A Stuart | Stat Med | 2015 | 26238958 | No |
3546 | 1097 | 1097.0 | 18.85 | 18.9 | Cell lines derived from late embryonic stages of Drosophila melanogaster. | I Schneider | J Embryol Exp Morphol | 1972 | 4625067 | Yes |
3547 | 6582 | 1097.0 | 142.93 | 23.8 | Obesity is associated with macrophage accumulation in adipose tissue. | Stuart P Weisberg, Daniel McCann, Manisha Desai, Michael Rosenbaum, Rudolph L Leibel, Anthony W Ferrante | J Clin Invest | 2003 | 14679176 | Yes |
3548 | 1097 | 1097.0 | 24.21 | 24.2 | Personal genomes: The case of the missing heritability. | Brendan Maher | Nature | 2008 | 18987709 | No |
3549 | 1097 | 1097.0 | 28.19 | 28.2 | Ovarian cancer development and metastasis. | Ernst Lengyel | Am J Pathol | 2010 | 20651229 | Yes |
3550 | 1096 | 1096.0 | 55.06 | 55.1 | Osseointegration and its experimental background. | P I Brånemark | J Prosthet Dent | 1983 | 6352924 | No |
3551 | 1096 | 1096.0 | 20.26 | 20.3 | Chronic myeloid leukemia. | C L Sawyers | N Engl J Med | 1999 | 10219069 | No |
3552 | 1096 | 1096.0 | 27.34 | 27.3 | Pathogenesis of osteoporosis: concepts, conflicts, and prospects. | Lawrence G Raisz | J Clin Invest | 2005 | 16322775 | No |
3553 | 3288 | 1096.0 | 585.12 | 195.0 | MEGA11: Molecular Evolutionary Genetics Analysis Version 11. | Koichiro Tamura, Glen Stecher, Sudhir Kumar | Mol Biol Evol | 2021 | 33892491 | Yes |
3554 | 2191 | 1095.5 | 65.6 | 32.8 | 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. | A Poland, J C Knutson | Annu Rev Pharmacol Toxicol | 1982 | 6282188 | No |
3555 | 2191 | 1095.5 | 57.8 | 28.9 | Localized surface plasmon resonance spectroscopy and sensing. | Katherine A Willets, Richard P Van Duyne | Annu Rev Phys Chem | 2007 | 17067281 | No |
3556 | 1095 | 1095.0 | 18.98 | 19.0 | Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast. | R Rothstein | Methods Enzymol | 1991 | 2005793 | Yes |
3557 | 1095 | 1095.0 | 20.75 | 20.8 | Luciferase reporter gene vectors for analysis of promoters and enhancers. | S K Nordeen | Biotechniques | 1988 | 2908509 | Yes |
3558 | 1095 | 1095.0 | 0.0 | 0.0 | Motivation reconsidered: the concept of competence. | R W White | Psychol Rev | 1959 | 13844397 | Yes |
3559 | 1095 | 1095.0 | 0.0 | 0.0 | The purine and pyrimidine composition of deoxypentose nucleic acids. | G R Wyatt | Biochem J | 1951 | 14838906 | Yes |
3560 | 1095 | 1095.0 | 32.81 | 32.8 | Social support and patient adherence to medical treatment: a meta-analysis. | M Robin DiMatteo | Health Psychol | 2004 | 15008666 | Yes |
3561 | 3285 | 1095.0 | 76.08 | 25.4 | Obesity induces a phenotypic switch in adipose tissue macrophage polarization. | Carey N Lumeng, Jennifer L Bodzin, Alan R Saltiel | J Clin Invest | 2007 | 17200717 | Yes |
3562 | 2189 | 1094.5 | 45.79 | 22.9 | The Hsp70 and Hsp60 chaperone machines. | B Bukau, A L Horwich | Cell | 1998 | 9476895 | No |
3563 | 2189 | 1094.5 | 53.8 | 26.9 | Quorum sensing: cell-to-cell communication in bacteria. | Christopher M Waters, Bonnie L Bassler | Annu Rev Cell Dev Biol | 2005 | 16212498 | No |
3564 | 1094 | 1094.0 | 27.7 | 27.7 | Two distinct classes of carbohydrate-recognition domains in animal lectins. | K Drickamer | J Biol Chem | 1988 | 3290208 | No |
3565 | 2188 | 1094.0 | 77.62 | 38.8 | Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry. | A I Basbaum, H L Fields | Annu Rev Neurosci | 1984 | 6143527 | No |
3566 | 1094 | 1094.0 | 22.41 | 22.4 | mRNA stability in mammalian cells. | J Ross | Microbiol Rev | 1995 | 7565413 | No |
3567 | 1094 | 1094.0 | 27.99 | 28.0 | Glutathione and its role in cellular functions. | H Sies | Free Radic Biol Med | 1999 | 10569624 | No |
3568 | 3282 | 1094.0 | 101.62 | 33.9 | PedsQL 4.0: reliability and validity of the Pediatric Quality of Life Inventory version 4.0 generic core scales in healthy and patient populations. | J W Varni, M Seid, P S Kurtin | Med Care | 2001 | 11468499 | Yes |
3569 | 1094 | 1094.0 | 27.05 | 27.1 | Seed Germination and Dormancy. | J. D. Bewley | Plant Cell | 1997 | 12237375 | Yes |
3570 | 2187 | 1093.5 | 0.0 | 0.0 | Micromethod for the direct determination of serum triglycerides. | E Van Handel, D B Zilversmit | J Lab Clin Med | 1957 | 13439279 | Yes |
3571 | 1093 | 1093.0 | 32.63 | 32.6 | Tests for emotionality in rats and mice: a review. | J Archer | Anim Behav | 1973 | 4578750 | No |
3572 | 1093 | 1093.0 | 32.31 | 32.3 | Spatially heterogeneous dynamics in supercooled liquids. | M D Ediger | Annu Rev Phys Chem | 2000 | 11031277 | Yes |
3573 | 1093 | 1093.0 | 25.04 | 25.0 | The prefrontal cortex--an update: time is of the essence. | J M Fuster | Neuron | 2001 | 11394996 | No |
3574 | 1093 | 1093.0 | 46.43 | 46.4 | CONSORT-EHEALTH: improving and standardizing evaluation reports of Web-based and mobile health interventions. | Gunther Eysenbach | J Med Internet Res | 2011 | 22209829 | No |
3575 | 1092 | 1092.0 | 38.49 | 38.5 | Spin trapping: ESR parameters of spin adducts. | G R Buettner | Free Radic Biol Med | 1987 | 2826304 | No |
3576 | 1092 | 1092.0 | 42.96 | 43.0 | Corticosteroids and lymphoid cells. | H N Claman | N Engl J Med | 1972 | 5043524 | Yes |
3577 | 1092 | 1092.0 | 33.98 | 34.0 | The oxidation hypothesis of atherosclerosis. | J L Witztum | Lancet | 1994 | 7916078 | No |
3578 | 5460 | 1092.0 | 114.98 | 23.0 | The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. | J W Harper, G R Adami, N Wei, K Keyomarsi, S J Elledge | Cell | 1993 | 8242751 | Yes |
3579 | 1092 | 1092.0 | 25.25 | 25.2 | P-450 metabolites of arachidonic acid in the control of cardiovascular function. | Richard J Roman | Physiol Rev | 2002 | 11773611 | No |
3580 | 2184 | 1092.0 | 74.54 | 37.3 | The complexity of NF-κB signaling in inflammation and cancer. | Bastian Hoesel, Johannes A Schmid | Mol Cancer | 2013 | 23915189 | No |
3581 | 3274 | 1091.3 | 98.09 | 32.7 | Depression: a new animal model sensitive to antidepressant treatments. | R D Porsolt, M Le Pichon, M Jalfre | Nature | 1977 | 559941 | Yes |
3582 | 1091 | 1091.0 | 27.64 | 27.6 | Selectins: interpreters of cell-specific carbohydrate information during inflammation. | L A Lasky | Science | 1992 | 1439808 | No |
3583 | 1091 | 1091.0 | 29.24 | 29.2 | A kinetic photometric method for serum gamma-glutamyl transpeptidase. | G Szasz | Clin Chem | 1969 | 5773262 | Yes |
3584 | 2181 | 1090.5 | 105.06 | 52.5 | Functional Classification and Experimental Dissection of Long Noncoding RNAs. | Florian Kopp, Joshua T Mendell | Cell | 2018 | 29373828 | No |
3585 | 1090 | 1090.0 | 19.75 | 19.8 | Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. | R A Frye | Biochem Biophys Res Commun | 2000 | 10873683 | Yes |
3586 | 1090 | 1090.0 | 25.93 | 25.9 | Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. | Thomas A Wynn | J Clin Invest | 2007 | 17332879 | No |
3587 | 2179 | 1089.5 | 68.77 | 34.4 | Glutamate and the pathophysiology of hypoxic--ischemic brain damage. | S M Rothman, J W Olney | Ann Neurol | 1986 | 2421636 | No |
3588 | 2179 | 1089.5 | 49.95 | 25.0 | Hepatitis C virus infection. | G M Lauer, B D Walker | N Engl J Med | 2001 | 11439948 | No |
3589 | 2179 | 1089.5 | 47.97 | 24.0 | Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. | Daniel J Hicklin, Lee M Ellis | J Clin Oncol | 2005 | 15585754 | No |
3590 | 3268 | 1089.3 | 177.21 | 59.1 | Hepatocellular carcinoma. | Alejandro Forner, María Reig, Jordi Bruix | Lancet | 2018 | 29307467 | No |
3591 | 2178 | 1089.0 | 43.66 | 21.8 | Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm. | P E Wright, H J Dyson | J Mol Biol | 1999 | 10550212 | No |
3592 | 1089 | 1089.0 | 0.0 | 0.0 | Aniline hydrogen phthalate as a spraying reagent for chromatography of sugars. | S M Partridge | Nature | 1949 | 18140444 | Yes |
3593 | 5444 | 1088.8 | 164.12 | 32.8 | Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. | Salim Yusuf, Bertram Pitt, Clarence E Davis, William B Hood, Jay N Cohn | N Engl J Med | 1991 | 2057034 | Yes |
3594 | 2177 | 1088.5 | 64.23 | 32.1 | Are the dorsal and ventral hippocampus functionally distinct structures? | Michael S Fanselow, Hong-Wei Dong | Neuron | 2010 | 20152109 | No |
3595 | 2176 | 1088.0 | 81.81 | 40.9 | Understanding face recognition. | V Bruce, A Young | Br J Psychol | 1986 | 3756376 | Yes |
3596 | 1088 | 1088.0 | 24.63 | 24.6 | Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes: a proposal for a synonymous codon choice that is optimal for the E. coli translational system. | T Ikemura | J Mol Biol | 1981 | 6175758 | Yes |
3597 | 2176 | 1088.0 | 74.3 | 37.1 | Consensus methods for medical and health services research. | J Jones, D Hunter | BMJ | 1995 | 7640549 | No |
3598 | 1088 | 1088.0 | 7.82 | 7.8 | Cardiac nucleotides in hypoxia: possible role in regulation of coronary blood flow. | R M Berne | Am J Physiol | 1963 | 13971060 | Yes |
3599 | 1088 | 1088.0 | 25.49 | 25.5 | Perylene bisimide dyes as versatile building blocks for functional supramolecular architectures. | Frank Würthner | Chem Commun (Camb) | 2004 | 15263926 | Yes |
3600 | 1088 | 1088.0 | 23.36 | 23.4 | Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology. | Michael Forgac | Nat Rev Mol Cell Biol | 2007 | 17912264 | No |
3601 | 6527 | 1087.8 | 159.35 | 26.6 | Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. | S Yusuf, P Sleight, J Pogue, J Bosch, R Davies, G Dagenais | N Engl J Med | 2000 | 10639539 | Yes |
3602 | 1087 | 1087.0 | 42.48 | 42.5 | A simple method for determination of serum catalase activity and revision of reference range. | L Góth | Clin Chim Acta | 1991 | 2029780 | Yes |
3603 | 1087 | 1087.0 | 27.59 | 27.6 | Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol. | M J Berridge | Biochem J | 1983 | 6309155 | Yes |
3604 | 1087 | 1087.0 | 22.98 | 23.0 | Twilight zone of protein sequence alignments. | B Rost | Protein Eng | 1999 | 10195279 | Yes |
3605 | 1087 | 1087.0 | 0.0 | 0.0 | Asymptomatic infections of the urinary tract. | E H Kass | Trans Assoc Am Physicians | 1956 | 13380946 | Yes |
3606 | 2173 | 1086.5 | 79.97 | 40.0 | The Modified Mini-Mental State (3MS) examination. | E L Teng, H C Chui | J Clin Psychiatry | 1987 | 3611032 | Yes |
3607 | 1086 | 1086.0 | 55.02 | 55.0 | The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): a clinical investigation of 225 patients using ambulatory 24-hour pH monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury. | J A Koufman | Laryngoscope | 1991 | 1895864 | No |
3608 | 1086 | 1086.0 | 30.84 | 30.8 | Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are onco-developmental antigens. | T Feizi | Nature | 1985 | 2579340 | Yes |
3609 | 2172 | 1086.0 | 50.96 | 25.5 | Peroxidase-labeled antibody. A new method of conjugation. | P K Nakane, A Kawaoi | J Histochem Cytochem | 1974 | 4443551 | Yes |
3610 | 1086 | 1086.0 | 25.13 | 25.1 | Selectins and their ligands: current concepts and controversies. | G S Kansas | Blood | 1996 | 8896391 | No |
3611 | 1086 | 1086.0 | 23.89 | 23.9 | Molecular mechanisms of myocardial remodeling. | B Swynghedauw | Physiol Rev | 1999 | 9922372 | No |
3612 | 1086 | 1086.0 | 29.83 | 29.8 | Cholinesterase inhibitors for Alzheimer's disease. | J Birks | Cochrane Database Syst Rev | 2006 | 16437532 | No |
3613 | 1086 | 1086.0 | 46.25 | 46.2 | A comprehensive review on metabolic syndrome. | Jaspinder Kaur | Cardiol Res Pract | 2014 | 24711954 | No |
3614 | 2171 | 1085.5 | 0.0 | 0.0 | A revision of the Schoenheimer-Sperry method for cholesterol determination. | W M Sperry, M Webb | J Biol Chem | 1950 | 14794694 | Yes |
3615 | 5426 | 1085.2 | 302.41 | 60.5 | ModelFinder: fast model selection for accurate phylogenetic estimates. | Subha Kalyaanamoorthy, Bui Quang Minh, Thomas K F Wong, Arndt von Haeseler, Lars S Jermiin | Nat Methods | 2017 | 28481363 | Yes |
3616 | 1085 | 1085.0 | 37.29 | 37.3 | Multiple organ failure. Pathophysiology and potential future therapy. | E A Deitch | Ann Surg | 1992 | 1503516 | No |
3617 | 1085 | 1085.0 | 20.59 | 20.6 | At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells. | M Kozak | J Mol Biol | 1987 | 3681984 | Yes |
3618 | 1085 | 1085.0 | 23.75 | 23.8 | New ideas about atrial fibrillation 50 years on. | Stanley Nattel | Nature | 2002 | 11805846 | No |
3619 | 1085 | 1085.0 | 0.0 | 0.0 | The concentration of sympathin in different parts of the central nervous system under normal conditions and after the administration of drugs. | M Vogt | J Physiol | 1954 | 13152692 | Yes |
3620 | 2170 | 1085.0 | 60.72 | 30.4 | Burden of major musculoskeletal conditions. | Anthony D Woolf, Bruce Pfleger | Bull World Health Organ | 2003 | 14710506 | No |
3621 | 6507 | 1084.5 | 167.56 | 27.9 | The capsaicin receptor: a heat-activated ion channel in the pain pathway. | M J Caterina, M A Schumacher, M Tominaga, T A Rosen, J D Levine, D Julius | Nature | 1997 | 9349813 | Yes |
3622 | 2168 | 1084.0 | 81.66 | 40.8 | Visual search and stimulus similarity. | J Duncan, G W Humphreys | Psychol Rev | 1989 | 2756067 | Yes |
3623 | 1084 | 1084.0 | 26.56 | 26.6 | DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability. | J F Ward | Prog Nucleic Acid Res Mol Biol | 1988 | 3065826 | No |
3624 | 1084 | 1084.0 | 23.3 | 23.3 | PHD: predicting one-dimensional protein structure by profile-based neural networks. | B Rost | Methods Enzymol | 1996 | 8743704 | Yes |
3625 | 1084 | 1084.0 | 20.31 | 20.3 | Progress in human tumour immunology and immunotherapy. | S A Rosenberg | Nature | 2001 | 11357146 | No |
3626 | 1083 | 1083.0 | 41.68 | 41.7 | A new international staging system for lung cancer. | C F Mountain | Chest | 1986 | 3514171 | No |
3627 | 1083 | 1083.0 | 32.48 | 32.5 | A teacher rating scale for use in drug studies with children. | C K Conners | Am J Psychiatry | 1969 | 4900822 | Yes |
3628 | 2166 | 1083.0 | 47.2 | 23.6 | Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age. | T Hunter, J Pines | Cell | 1994 | 7954824 | No |
3629 | 1083 | 1083.0 | 30.46 | 30.5 | Limbic-cortical dysregulation: a proposed model of depression. | H S Mayberg | J Neuropsychiatry Clin Neurosci | 1997 | 9276848 | No |
3630 | 2165 | 1082.5 | 66.92 | 33.5 | Mental rotation of three-dimensional objects. | R N Shepard, J Metzler | Science | 1971 | 5540314 | Yes |
3631 | 2164 | 1082.0 | 64.97 | 32.5 | A rapid, sensitive, and versatile assay for protein using Coomassie brilliant blue G250. | J J Sedmak, S E Grossberg | Anal Biochem | 1977 | 68686 | Yes |
3632 | 1082 | 1082.0 | 25.15 | 25.1 | BIONJ: an improved version of the NJ algorithm based on a simple model of sequence data. | O Gascuel | Mol Biol Evol | 1997 | 9254330 | Yes |
3633 | 2163 | 1081.5 | 63.43 | 31.7 | Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation. | J M Reul, E R de Kloet | Endocrinology | 1985 | 2998738 | Yes |
3634 | 1081 | 1081.0 | 32.77 | 32.8 | Association of the B-cell alloantigen DRw4 with rheumatoid arthritis. | P Stastny | N Engl J Med | 1978 | 147420 | Yes |
3635 | 1081 | 1081.0 | 58.03 | 58.0 | The stabilizing system of the spine. Part I. Function, dysfunction, adaptation, and enhancement. | M M Panjabi | J Spinal Disord | 1992 | 1490034 | Yes |
3636 | 1081 | 1081.0 | 20.72 | 20.7 | Radiochemical micro assays for the determination of choline acetyltransferase and acetylcholinesterase activities. | F Fonnum | Biochem J | 1969 | 4982085 | Yes |
3637 | 2162 | 1081.0 | 82.67 | 41.3 | The Posttraumatic Growth Inventory: measuring the positive legacy of trauma. | R G Tedeschi, L G Calhoun | J Trauma Stress | 1996 | 8827649 | Yes |
3638 | 1081 | 1081.0 | 0.0 | 0.0 | The stereotaxic method and radiosurgery of the brain. | L Leksell | Acta Chir Scand | 1951 | 14914373 | Yes |
3639 | 1081 | 1081.0 | 28.56 | 28.6 | Abiotic stress, the field environment and stress combination. | Ron Mittler | Trends Plant Sci | 2006 | 16359910 | No |
3640 | 2162 | 1081.0 | 154.03 | 77.0 | OrthoFinder: phylogenetic orthology inference for comparative genomics. | David M Emms, Steven Kelly | Genome Biol | 2019 | 31727128 | Yes |
3641 | 3242 | 1080.7 | 84.67 | 28.2 | Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. | M K Parmar, V Torri, L Stewart | Stat Med | 1998 | 9921604 | Yes |
3642 | 2161 | 1080.5 | 45.14 | 22.6 | Mitogen-activated protein kinase pathways. | M J Robinson, M H Cobb | Curr Opin Cell Biol | 1997 | 9069255 | No |
3643 | 2161 | 1080.5 | 60.6 | 30.3 | ASCORBATE AND GLUTATHIONE: Keeping Active Oxygen Under Control. | Graham Noctor, Christine H. Foyer | Annu Rev Plant Physiol Plant Mol Biol | 1998 | 15012235 | Yes |
3644 | 2161 | 1080.5 | 75.92 | 38.0 | A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation. | Walter J Paulus, Carsten Tschöpe | J Am Coll Cardiol | 2013 | 23684677 | No |
3645 | 4321 | 1080.2 | 207.01 | 51.8 | Genome sequence-based species delimitation with confidence intervals and improved distance functions. | Jan P Meier-Kolthoff, Alexander F Auch, Hans-Peter Klenk, Markus Göker | BMC Bioinformatics | 2013 | 23432962 | Yes |
3646 | 1080 | 1080.0 | 61.69 | 61.7 | The contribution of the social environment to host resistance: the Fourth Wade Hampton Frost Lecture. | J Cassel | Am J Epidemiol | 1976 | 782233 | No |
3647 | 1080 | 1080.0 | 30.21 | 30.2 | Transport of molecules in the tumor interstitium: a review. | R K Jain | Cancer Res | 1987 | 3555767 | No |
3648 | 1080 | 1080.0 | 21.38 | 21.4 | Coiled coils: new structures and new functions. | A Lupas | Trends Biochem Sci | 1996 | 8918191 | No |
3649 | 1080 | 1080.0 | 29.15 | 29.1 | What you see may not be what you get: a brief, nontechnical introduction to overfitting in regression-type models. | Michael A Babyak | Psychosom Med | 2004 | 15184705 | Yes |
3650 | 1080 | 1080.0 | 21.41 | 21.4 | Nonlinear structured-illumination microscopy: wide-field fluorescence imaging with theoretically unlimited resolution. | Mats G L Gustafsson | Proc Natl Acad Sci U S A | 2005 | 16141335 | Yes |
3651 | 1080 | 1080.0 | 20.78 | 20.8 | mTOR and cancer: insights into a complex relationship. | David M Sabatini | Nat Rev Cancer | 2006 | 16915295 | No |
3652 | 1079 | 1079.0 | 21.38 | 21.4 | Protein denaturation. C. Theoretical models for the mechanism of denaturation. | C Tanford | Adv Protein Chem | 1970 | 4912353 | No |
3653 | 1079 | 1079.0 | 22.34 | 22.3 | Likelihood ratio tests for detecting positive selection and application to primate lysozyme evolution. | Z Yang | Mol Biol Evol | 1998 | 9580986 | Yes |
3654 | 1079 | 1079.0 | 0.0 | 0.0 | The effect of emotion on cue utilization and the organization of behavior. | J A Easterbrook | Psychol Rev | 1959 | 13658305 | Yes |
3655 | 1079 | 1079.0 | 8.27 | 8.3 | The Permeability Of Capillaries In Various Organs As Determined By Use Of The 'Indicator Diffusion' Method. | C Crone | Acta Physiol Scand | 1963 | 14078649 | Yes |
3656 | 1079 | 1079.0 | 39.66 | 39.7 | The pathobiology of vascular dementia. | Costantino Iadecola | Neuron | 2013 | 24267647 | No |
3657 | 3236 | 1078.7 | 115.39 | 38.5 | Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. | P S Walsh, D A Metzger, R Higuchi | Biotechniques | 1991 | 1867860 | Yes |
3658 | 6472 | 1078.7 | 138.97 | 23.2 | Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. | D A Melton, P A Krieg, M R Rebagliati, T Maniatis, K Zinn, M R Green | Nucleic Acids Res | 1984 | 6091052 | Yes |
3659 | 1078 | 1078.0 | 56.32 | 56.3 | The tension-stress effect on the genesis and growth of tissues: Part II. The influence of the rate and frequency of distraction. | G A Ilizarov | Clin Orthop Relat Res | 1989 | 2912628 | Yes |
3660 | 1078 | 1078.0 | 18.83 | 18.8 | Regulatory T cells in autoimmmunity*. | E M Shevach | Annu Rev Immunol | 2000 | 10837065 | No |
3661 | 1078 | 1078.0 | 18.31 | 18.3 | Molecular mechanisms of axon guidance. | Barry J Dickson | Science | 2002 | 12471249 | No |
3662 | 1078 | 1078.0 | 25.85 | 25.9 | ImageJ for microscopy. | Tony J Collins | Biotechniques | 2007 | 17936939 | No |
3663 | 1078 | 1078.0 | 33.59 | 33.6 | Lanthanide luminescence for biomedical analyses and imaging. | Jean-Claude G Bünzli | Chem Rev | 2010 | 20151630 | No |
3664 | 4311 | 1077.8 | 157.25 | 39.3 | Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. | K F Schulz, I Chalmers, R J Hayes, D G Altman | JAMA | 1995 | 7823387 | Yes |
3665 | 2154 | 1077.0 | 43.53 | 21.8 | In search of the 'missing self': MHC molecules and NK cell recognition. | H G Ljunggren, K Kärre | Immunol Today | 1990 | 2201309 | No |
3666 | 1077 | 1077.0 | 25.39 | 25.4 | Nitric oxide, oxidants, and protein tyrosine nitration. | Rafael Radi | Proc Natl Acad Sci U S A | 2004 | 15020765 | Yes |
3667 | 1077 | 1077.0 | 27.09 | 27.1 | Fibrinogen and fibrin structure and functions. | M W Mosesson | J Thromb Haemost | 2005 | 16102057 | No |
3668 | 2154 | 1077.0 | 65.65 | 32.8 | Ischemia and reperfusion--from mechanism to translation. | Holger K Eltzschig, Tobias Eckle | Nat Med | 2011 | 22064429 | No |
3669 | 1077 | 1077.0 | 38.06 | 38.1 | Epidemiology of heart failure. | Véronique L Roger | Circ Res | 2013 | 23989710 | No |
3670 | 2153 | 1076.5 | 96.44 | 48.2 | Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics. | J B Mulliken, J Glowacki | Plast Reconstr Surg | 1982 | 7063565 | Yes |
3671 | 2152 | 1076.0 | 74.63 | 37.3 | A formula to estimate the approximate surface area if height and weight be known. 1916. | D Du Bois, E F Du Bois | Nutrition | 1989 | 2520314 | No |
3672 | 1076 | 1076.0 | 24.83 | 24.8 | Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology. | E M Tan | Adv Immunol | 1989 | 2646863 | No |
3673 | 1076 | 1076.0 | 16.0 | 16.0 | The moulding of senescence by natural selection. | W D Hamilton | J Theor Biol | 1966 | 6015424 | Yes |
3674 | 1076 | 1076.0 | 36.03 | 36.0 | Lipid peroxidation and antioxidants as biomarkers of tissue damage. | J M Gutteridge | Clin Chem | 1995 | 7497639 | No |
3675 | 1076 | 1076.0 | 35.83 | 35.8 | Why we need observational studies to evaluate the effectiveness of health care. | N Black | BMJ | 1996 | 8634569 | Yes |
3676 | 2151 | 1075.5 | 39.69 | 19.8 | AP-1 as a regulator of cell life and death. | Eitan Shaulian, Michael Karin | Nat Cell Biol | 2002 | 11988758 | No |
3677 | 2151 | 1075.5 | 41.86 | 20.9 | STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. | Hiroki Ishikawa, Glen N Barber | Nature | 2008 | 18724357 | Yes |
3678 | 1075 | 1075.0 | 31.23 | 31.2 | Why people use health services. | I M Rosenstock | Milbank Mem Fund Q | 1966 | 5967464 | Yes |
3679 | 1075 | 1075.0 | 37.82 | 37.8 | Coronary physiology. | E O Feigl | Physiol Rev | 1983 | 6296890 | No |
3680 | 1075 | 1075.0 | 40.2 | 40.2 | Beyond curriculum reform: confronting medicine's hidden curriculum. | F W Hafferty | Acad Med | 1998 | 9580717 | Yes |
3681 | 2150 | 1075.0 | 46.22 | 23.1 | Finding and evaluating community structure in networks. | M E J Newman, M Girvan | Phys Rev E Stat Nonlin Soft Matter Phys | 2004 | 14995526 | Yes |
3682 | 2150 | 1075.0 | 61.12 | 30.6 | Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for Gram-negative bacteria. | Ivan Sondi, Branka Salopek-Sondi | J Colloid Interface Sci | 2004 | 15158396 | Yes |
3683 | 1075 | 1075.0 | 72.81 | 72.8 | Non-alcoholic fatty liver disease - A global public health perspective. | Zobair M Younossi | J Hepatol | 2019 | 30414863 | No |
3684 | 2150 | 1075.0 | 247.54 | 123.8 | Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019. | David J Newman, Gordon M Cragg | J Nat Prod | 2020 | 32162523 | No |
3685 | 3223 | 1074.3 | 127.24 | 42.4 | Concurrent and predictive validity of a self-reported measure of medication adherence. | D E Morisky, L W Green, D M Levine | Med Care | 1986 | 3945130 | Yes |
3686 | 1074 | 1074.0 | 27.4 | 27.4 | Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system. | J P Tam | Proc Natl Acad Sci U S A | 1988 | 3399498 | Yes |
3687 | 1074 | 1074.0 | 28.67 | 28.7 | Statistical quality control and routine data processing for radioimmunoassays and immunoradiometric assays. | D Rodbard | Clin Chem | 1974 | 4370388 | No |
3688 | 1074 | 1074.0 | 28.32 | 28.3 | Microtubule formation in vitro in solutions containing low calcium concentrations. | R C Weisenberg | Science | 1972 | 4626639 | Yes |
3689 | 1074 | 1074.0 | 28.43 | 28.4 | Invited review: Aging and sarcopenia. | Timothy J Doherty | J Appl Physiol (1985) | 2003 | 12970377 | No |
3690 | 1074 | 1074.0 | 30.03 | 30.0 | The locus coeruleus and noradrenergic modulation of cognition. | Susan J Sara | Nat Rev Neurosci | 2009 | 19190638 | No |
3691 | 3221 | 1073.7 | 63.05 | 21.0 | Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. | Paola Scaffidi, Tom Misteli, Marco E Bianchi | Nature | 2002 | 12110890 | Yes |
3692 | 2147 | 1073.5 | 83.56 | 41.8 | Glutathione reductase. | I Carlberg, B Mannervik | Methods Enzymol | 1985 | 3003504 | Yes |
3693 | 2147 | 1073.5 | 83.28 | 41.6 | Chronic catheterization of the spinal subarachnoid space. | T L Yaksh, T A Rudy | Physiol Behav | 1976 | 14677603 | Yes |
3694 | 1073 | 1073.0 | 41.63 | 41.6 | Functional connections between cells as revealed by dye-coupling with a highly fluorescent naphthalimide tracer. | W W Stewart | Cell | 1978 | 688392 | Yes |
3695 | 2146 | 1073.0 | 43.07 | 21.5 | A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli. | C S Hoffman, F Winston | Gene | 1987 | 3319781 | Yes |
3696 | 1073 | 1073.0 | 23.41 | 23.4 | ECM and cell surface proteolysis: regulating cellular ecology. | Z Werb | Cell | 1997 | 9390552 | No |
3697 | 1073 | 1073.0 | 31.05 | 31.1 | Microbial heavy-metal resistance. | D H Nies | Appl Microbiol Biotechnol | 1999 | 10422221 | No |
3698 | 1073 | 1073.0 | 32.8 | 32.8 | On the mechanisms of biocompatibility. | David F Williams | Biomaterials | 2008 | 18440630 | No |
3699 | 6435 | 1072.5 | 174.32 | 29.1 | Cancer statistics, 2007. | Ahmedin Jemal, Rebecca Siegel, Elizabeth Ward, Taylor Murray, Jiaquan Xu, Michael J Thun | CA Cancer J Clin | 2007 | 17237035 | Yes |
3700 | 2145 | 1072.5 | 60.4 | 30.2 | Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. | Amit Etkin, Tor D Wager | Am J Psychiatry | 2007 | 17898336 | Yes |
3701 | 2144 | 1072.0 | 82.57 | 41.3 | Hearing lips and seeing voices. | H McGurk, J MacDonald | Nature | 1976 | 1012311 | Yes |
3702 | 1072 | 1072.0 | 33.27 | 33.3 | Food reward: brain substrates of wanting and liking. | K C Berridge | Neurosci Biobehav Rev | 1996 | 8622814 | No |
3703 | 3216 | 1072.0 | 152.29 | 50.8 | Development of an upper extremity outcome measure: the DASH (disabilities of the arm, shoulder and hand) [corrected]. The Upper Extremity Collaborative Group (UECG) | P L Hudak, P C Amadio, C Bombardier | Am J Ind Med | 1996 | 8773720 | Yes |
3704 | 1072 | 1072.0 | 29.08 | 29.1 | Ion suppression in mass spectrometry. | Thomas M Annesley | Clin Chem | 2003 | 12816898 | No |
3705 | 1072 | 1072.0 | 28.91 | 28.9 | A perspective on judgment and choice: mapping bounded rationality. | Daniel Kahneman | Am Psychol | 2003 | 14584987 | No |
3706 | 1072 | 1072.0 | 29.56 | 29.6 | Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review. | John W Newcomer | CNS Drugs | 2005 | 15998156 | No |
3707 | 1072 | 1072.0 | 27.34 | 27.3 | Redefining oxidative stress. | Dean P Jones | Antioxid Redox Signal | 2006 | 16987039 | No |
3708 | 4288 | 1072.0 | 241.74 | 60.4 | The Cambridge Structural Database. | Colin R Groom, Ian J Bruno, Matthew P Lightfoot, Suzanna C Ward | Acta Crystallogr B Struct Sci Cryst Eng Mater | 2016 | 27048719 | Yes |
3709 | 1071 | 1071.0 | 18.12 | 18.1 | Evolution and tinkering. | F Jacob | Science | 1977 | 860134 | Yes |
3710 | 1071 | 1071.0 | 27.43 | 27.4 | Unequal treatment: confronting racial and ethnic disparities in health care. | Alan Nelson | J Natl Med Assoc | 2002 | 12152921 | No |
3711 | 1071 | 1071.0 | 24.02 | 24.0 | Liver regeneration. | George K Michalopoulos | J Cell Physiol | 2007 | 17559071 | No |
3712 | 1071 | 1071.0 | 28.26 | 28.3 | Bile acids: regulation of synthesis. | John Y L Chiang | J Lipid Res | 2009 | 19346330 | No |
3713 | 1070 | 1070.0 | 29.75 | 29.8 | Mitochondrial genetics: a paradigm for aging and degenerative diseases? | D C Wallace | Science | 1992 | 1533953 | Yes |
3714 | 1070 | 1070.0 | 26.37 | 26.4 | Anti-inflammatory actions of glucocorticoids: molecular mechanisms. | P J Barnes | Clin Sci (Lond) | 1998 | 9854452 | No |
3715 | 3210 | 1070.0 | 75.31 | 25.1 | Arabidopsis mesophyll protoplasts: a versatile cell system for transient gene expression analysis. | Sang-Dong Yoo, Young-Hee Cho, Jen Sheen | Nat Protoc | 2007 | 17585298 | Yes |
3716 | 1070 | 1070.0 | 31.35 | 31.4 | Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy. | Gregg L Semenza | Trends Pharmacol Sci | 2012 | 22398146 | No |
3717 | 1070 | 1070.0 | 55.25 | 55.2 | Systematic text condensation: a strategy for qualitative analysis. | Kirsti Malterud | Scand J Public Health | 2012 | 23221918 | Yes |
3718 | 2139 | 1069.5 | 54.21 | 27.1 | Antibacterial resistance worldwide: causes, challenges and responses. | Stuart B Levy, Bonnie Marshall | Nat Med | 2004 | 15577930 | No |
3719 | 2138 | 1069.0 | 90.78 | 45.4 | Severe psoriasis--oral therapy with a new retinoid. | T Fredriksson, U Pettersson | Dermatologica | 1978 | 357213 | Yes |
3720 | 1069 | 1069.0 | 27.08 | 27.1 | Axonal growth-associated proteins. | J H Skene | Annu Rev Neurosci | 1989 | 2648946 | No |
3721 | 1069 | 1069.0 | 26.25 | 26.2 | Biological effects of resveratrol. | L Frémont | Life Sci | 2000 | 10680575 | No |
3722 | 1069 | 1069.0 | 26.45 | 26.4 | The glycemic index: physiological mechanisms relating to obesity, diabetes, and cardiovascular disease. | David S Ludwig | JAMA | 2002 | 11988062 | No |
3723 | 1069 | 1069.0 | 29.5 | 29.5 | Principles of c-di-GMP signalling in bacteria. | Regine Hengge | Nat Rev Microbiol | 2009 | 19287449 | No |
3724 | 2137 | 1068.5 | 71.48 | 35.7 | The pathogenesis of atherosclerosis (first of two parts). | R Ross, J A Glomset | N Engl J Med | 1976 | 819830 | No |
3725 | 4274 | 1068.5 | 110.22 | 27.6 | A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. | I Vermes, C Haanen, H Steffens-Nakken, C Reutelingsperger | J Immunol Methods | 1995 | 7622868 | Yes |
3726 | 2136 | 1068.0 | 59.95 | 30.0 | Binding of soluble form of fibroblast surface protein, fibronectin, to collagen. | E Engvall, E Ruoslahti | Int J Cancer | 1977 | 903179 | Yes |
3727 | 1068 | 1068.0 | 50.2 | 50.2 | Clinical experience with impedance audiometry. | J Jerger | Arch Otolaryngol | 1970 | 5455571 | Yes |
3728 | 1068 | 1068.0 | 30.65 | 30.6 | Muscarinic receptors--characterization, coupling and function. | M P Caulfield | Pharmacol Ther | 1993 | 7504306 | No |
3729 | 2136 | 1068.0 | 37.48 | 18.7 | Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. | W Gu, R G Roeder | Cell | 1997 | 9288740 | Yes |
3730 | 1068 | 1068.0 | 24.69 | 24.7 | Structure and signalling in the IL-17 receptor family. | Sarah L Gaffen | Nat Rev Immunol | 2009 | 19575028 | No |
3731 | 4270 | 1067.5 | 109.4 | 27.4 | Real time quantitative PCR. | C A Heid, J Stevens, K J Livak, P M Williams | Genome Res | 1996 | 8908518 | Yes |
3732 | 11741 | 1067.4 | 332.96 | 30.3 | International physical activity questionnaire: 12-country reliability and validity. | Cora L Craig, Alison L Marshall, Michael Sjöström, Adrian E Bauman, Michael L Booth, Barbara E Ainsworth, Michael Pratt, Ulf Ekelund, Agneta Yngve, James F Sallis, Pekka Oja | Med Sci Sports Exerc | 2003 | 12900694 | Yes |
3733 | 1067 | 1067.0 | 25.84 | 25.8 | The ultrastructural basis of capillary permeability studied with peroxidase as a tracer. | M J Karnovsky | J Cell Biol | 1967 | 6061717 | Yes |
3734 | 1067 | 1067.0 | 30.24 | 30.2 | Autoantibodies to nuclear antigens (ANA): their immunobiology and medicine. | E M Tan | Adv Immunol | 1982 | 6182766 | No |
3735 | 2134 | 1067.0 | 75.47 | 37.7 | Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier. | Hirenkumar K Makadia, Steven J Siegel | Polymers (Basel) | 2011 | 22577513 | Yes |
3736 | 10665 | 1066.5 | 351.51 | 35.2 | The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. | N K Aaronson, S Ahmedzai, B Bergman, M Bullinger, A Cull, N J Duez, A Filiberti, H Flechtner, S B Fleishman, J C de Haes | J Natl Cancer Inst | 1993 | 8433390 | Yes |
3737 | 4264 | 1066.0 | 217.3 | 54.3 | National Institute of Mental Health Diagnostic Interview Schedule. Its history, characteristics, and validity. | L N Robins, J E Helzer, J Croughan, K S Ratcliff | Arch Gen Psychiatry | 1981 | 6260053 | Yes |
3738 | 1066 | 1066.0 | 24.16 | 24.2 | The neurobiology of consolidations, or, how stable is the engram? | Yadin Dudai | Annu Rev Psychol | 2004 | 14744210 | No |
3739 | 3197 | 1065.7 | 142.63 | 47.5 | Surface markers on human T and B lymphocytes. I. A large population of lymphocytes forming nonimmune rosettes with sheep red blood cells. | M Jondal, G Holm, H Wigzell | J Exp Med | 1972 | 4114496 | Yes |
3740 | 2131 | 1065.5 | 62.72 | 31.4 | Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. | C N Hales, D J Barker | Diabetologia | 1992 | 1644236 | No |
3741 | 3196 | 1065.3 | 67.47 | 22.5 | 5-fluorouracil: mechanisms of action and clinical strategies. | Daniel B Longley, D Paul Harkin, Patrick G Johnston | Nat Rev Cancer | 2003 | 12724731 | No |
3742 | 1065 | 1065.0 | 38.7 | 38.7 | Attention, similarity, and the identification-categorization relationship. | R M Nosofsky | J Exp Psychol Gen | 1986 | 2937873 | Yes |
3743 | 1065 | 1065.0 | 27.95 | 27.9 | Philosophical conceptions of the self: implications for cognitive science. | I Gallagher | Trends Cogn Sci | 2000 | 10637618 | Yes |
3744 | 1065 | 1065.0 | 32.64 | 32.6 | Social cognition and the brain: a meta-analysis. | Frank Van Overwalle | Hum Brain Mapp | 2009 | 18381770 | Yes |
3745 | 1065 | 1065.0 | 28.39 | 28.4 | An introduction to data reduction: space-group determination, scaling and intensity statistics. | Philip R Evans | Acta Crystallogr D Biol Crystallogr | 2011 | 21460446 | Yes |
3746 | 2130 | 1065.0 | 79.0 | 39.5 | Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. | Claudio Franceschi, Judith Campisi | J Gerontol A Biol Sci Med Sci | 2014 | 24833586 | No |
3747 | 2129 | 1064.5 | 42.06 | 21.0 | Calcium-dependent bacteriophage DNA infection. | M Mandel, A Higa | J Mol Biol | 1970 | 4922220 | Yes |
3748 | 1064 | 1064.0 | 21.76 | 21.8 | The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells. | D Metcalf | Nature | 1989 | 2469962 | No |
3749 | 1064 | 1064.0 | 52.53 | 52.5 | The sociological study of stress. | L I Pearlin | J Health Soc Behav | 1989 | 2674272 | No |
3750 | 1064 | 1064.0 | 29.16 | 29.2 | Synchronization of cortical activity and its putative role in information processing and learning. | W Singer | Annu Rev Physiol | 1993 | 8466179 | No |
3751 | 6384 | 1064.0 | 176.89 | 29.5 | Mild cognitive impairment: clinical characterization and outcome. | R C Petersen, G E Smith, S C Waring, R J Ivnik, E G Tangalos, E Kokmen | Arch Neurol | 1999 | 10190820 | Yes |
3752 | 2128 | 1064.0 | 54.11 | 27.1 | Anemia of chronic disease. | Guenter Weiss, Lawrence T Goodnough | N Engl J Med | 2005 | 15758012 | No |
3753 | 1063 | 1063.0 | 36.01 | 36.0 | A colorimetric method for estimating serum triglycerides. | M J Fletcher | Clin Chim Acta | 1968 | 5696963 | Yes |
3754 | 5315 | 1063.0 | 194.03 | 38.8 | A new clinical scale for the staging of dementia. | C P Hughes, L Berg, W L Danziger, L A Coben, R L Martin | Br J Psychiatry | 1982 | 7104545 | Yes |
3755 | 1063 | 1063.0 | 22.08 | 22.1 | Oxidant signals and oxidative stress. | Toren Finkel | Curr Opin Cell Biol | 2003 | 12648682 | No |
3756 | 4252 | 1063.0 | 101.32 | 25.3 | The epidemiology of sepsis in the United States from 1979 through 2000. | Greg S Martin, David M Mannino, Stephanie Eaton, Marc Moss | N Engl J Med | 2003 | 12700374 | Yes |
3757 | 1063 | 1063.0 | 25.83 | 25.8 | Looking into the functional architecture of the brain with diffusion MRI. | Denis Le Bihan | Nat Rev Neurosci | 2003 | 12778119 | No |
3758 | 2125 | 1062.5 | 53.2 | 26.6 | The regulation and function of c-fos and other immediate early genes in the nervous system. | M Sheng, M E Greenberg | Neuron | 1990 | 1969743 | No |
3759 | 2125 | 1062.5 | 56.29 | 28.1 | The evolution of cooperation. | R Axelrod, W D Hamilton | Science | 1981 | 7466396 | Yes |
3760 | 1062 | 1062.0 | 25.51 | 25.5 | The granulocyte-macrophage colony-stimulating factors. | D Metcalf | Science | 1985 | 2990035 | No |
3761 | 1062 | 1062.0 | 29.82 | 29.8 | Junctional intercellular communication: the cell-to-cell membrane channel. | W R Loewenstein | Physiol Rev | 1981 | 6270711 | No |
3762 | 1062 | 1062.0 | 30.46 | 30.5 | Pathogenetic mechanisms of septic shock. | J E Parrillo | N Engl J Med | 1993 | 8479467 | No |
3763 | 1062 | 1062.0 | 28.62 | 28.6 | Interval estimation for the difference between independent proportions: comparison of eleven methods. | R G Newcombe | Stat Med | 1998 | 9595617 | Yes |
3764 | 1062 | 1062.0 | 25.5 | 25.5 | Context, ambiguity, and unlearning: sources of relapse after behavioral extinction. | Mark E Bouton | Biol Psychiatry | 2002 | 12437938 | No |
3765 | 2124 | 1062.0 | 51.93 | 26.0 | Sulforhodamine B colorimetric assay for cytotoxicity screening. | Vanicha Vichai, Kanyawim Kirtikara | Nat Protoc | 2006 | 17406391 | Yes |
3766 | 6370 | 1061.7 | 161.71 | 27.0 | Ghrelin is a growth-hormone-releasing acylated peptide from stomach. | M Kojima, H Hosoda, Y Date, M Nakazato, H Matsuo, K Kangawa | Nature | 1999 | 10604470 | Yes |
3767 | 5307 | 1061.4 | 144.28 | 28.9 | Biodiversity hotspots for conservation priorities. | N Myers, R A Mittermeier, C G Mittermeier, G A da Fonseca, J Kent | Nature | 2000 | 10706275 | Yes |
3768 | 1061 | 1061.0 | 31.62 | 31.6 | Epidemiology of cancer of the colon and rectum. | D P Burkitt | Cancer | 1971 | 5165022 | Yes |
3769 | 1061 | 1061.0 | 32.67 | 32.7 | Prevention of drug access to bacterial targets: permeability barriers and active efflux. | H Nikaido | Science | 1994 | 8153625 | No |
3770 | 1061 | 1061.0 | 30.03 | 30.0 | The mechanisms of alloxan- and streptozotocin-induced diabetes. | S Lenzen | Diabetologia | 2008 | 18087688 | No |
3771 | 1061 | 1061.0 | 0.0 | 0.0 | A Serological Differentiation Of Human And Other Groups Of Hemolytic Streptococci. | R C Lancefield | J Exp Med | 1933 | 19870148 | Yes |
3772 | 2122 | 1061.0 | 72.77 | 36.4 | Photoacoustic tomography: in vivo imaging from organelles to organs. | Lihong V Wang, Song Hu | Science | 2012 | 22442475 | No |
3773 | 2122 | 1061.0 | 116.67 | 58.3 | Sexually transmitted diseases treatment guidelines, 2015. | Kimberly A Workowski, Gail A Bolan | MMWR Recomm Rep | 2015 | 26042815 | No |
3774 | 3182 | 1060.7 | 80.92 | 27.0 | Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions. | M Piotto, V Saudek, V Sklenár | J Biomol NMR | 1992 | 1490109 | Yes |
3775 | 2121 | 1060.5 | 0.0 | 0.0 | Histochemistry of hepatic phosphatases of a physiologic pH; with special reference to the demonstration of bile canaliculi. | M Wachstein, E Meisel | Am J Clin Pathol | 1957 | 13410831 | Yes |
3776 | 2120 | 1060.0 | 61.84 | 30.9 | The biochemistry of P-glycoprotein-mediated multidrug resistance. | J A Endicott, V Ling | Annu Rev Biochem | 1989 | 2570548 | No |
3777 | 1060 | 1060.0 | 28.39 | 28.4 | Inhibition of return. | R M Klein | Trends Cogn Sci | 2000 | 10740278 | Yes |
3778 | 2120 | 1060.0 | 0.0 | 0.0 | Use of glucose oxidase, peroxidase, and O-dianisidine in determination of blood and urinary glucose. | A S Huggett, D A Nixon | Lancet | 1957 | 13464070 | Yes |
3779 | 1060 | 1060.0 | 28.34 | 28.3 | Neuronal gamma-band synchronization as a fundamental process in cortical computation. | Pascal Fries | Annu Rev Neurosci | 2009 | 19400723 | No |
3780 | 1060 | 1060.0 | 37.09 | 37.1 | Stochastic thermodynamics, fluctuation theorems and molecular machines. | Udo Seifert | Rep Prog Phys | 2012 | 23168354 | No |
3781 | 2120 | 1060.0 | 87.61 | 43.8 | Communication by Extracellular Vesicles: Where We Are and Where We Need to Go. | Mercedes Tkach, Clotilde Théry | Cell | 2016 | 26967288 | No |
3782 | 2119 | 1059.5 | 32.86 | 16.4 | The growth of mouse bone marrow cells in vitro. | T R Bradley, D Metcalf | Aust J Exp Biol Med Sci | 1966 | 4164182 | Yes |
3783 | 2119 | 1059.5 | 54.04 | 27.0 | Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. | M S Brown, J L Goldstein | Annu Rev Biochem | 1983 | 6311077 | No |
3784 | 1059 | 1059.0 | 39.32 | 39.3 | Infection by verocytotoxin-producing Escherichia coli. | M A Karmali | Clin Microbiol Rev | 1989 | 2644022 | No |
3785 | 1059 | 1059.0 | 24.46 | 24.5 | Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note. | S H Kaufmann | Cancer Res | 1989 | 2790800 | Yes |
3786 | 1059 | 1059.0 | 29.85 | 29.9 | Determination of total protein. | G L Peterson | Methods Enzymol | 1983 | 6855607 | Yes |
3787 | 1059 | 1059.0 | 41.5 | 41.5 | Gait changes in older adults: predictors of falls or indicators of fear. | B E Maki | J Am Geriatr Soc | 1997 | 9063277 | Yes |
3788 | 2118 | 1059.0 | 47.97 | 24.0 | The significance of digital gene expression profiles. | S Audic, J M Claverie | Genome Res | 1997 | 9331369 | Yes |
3789 | 2118 | 1059.0 | 40.11 | 20.1 | Wnt signaling: a common theme in animal development. | K M Cadigan, R Nusse | Genes Dev | 1997 | 9407023 | No |
3790 | 1059 | 1059.0 | 18.86 | 18.9 | Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. | W Kolch | Biochem J | 2000 | 11023813 | No |
3791 | 2118 | 1059.0 | 47.98 | 24.0 | Effect of pegylation on pharmaceuticals. | J Milton Harris, Robert B Chess | Nat Rev Drug Discov | 2003 | 12612647 | No |
3792 | 2118 | 1059.0 | 0.0 | 0.0 | A microcolorimetric method for the determination of inorganic phosphorus. | H H Taussky, E Shorr | J Biol Chem | 1953 | 13061491 | Yes |
3793 | 1059 | 1059.0 | 0.0 | 0.0 | On the Absorption of Fluids from the Connective Tissue Spaces. | E H Starling | J Physiol | 1896 | 16992325 | Yes |
3794 | 1059 | 1059.0 | 27.78 | 27.8 | Physiology and immunology of the cholinergic antiinflammatory pathway. | Kevin J Tracey | J Clin Invest | 2007 | 17273548 | No |
3795 | 3177 | 1059.0 | 86.63 | 28.9 | Improved vectors and genome-wide libraries for CRISPR screening. | Neville E Sanjana, Ophir Shalem, Feng Zhang | Nat Methods | 2014 | 25075903 | Yes |
3796 | 1059 | 1059.0 | 33.95 | 34.0 | Isolation By Distance In Equilibrium And Non-Equilibrium Populations. | Montgomery Slatkin | Evolution | 1993 | 28568097 | Yes |
3797 | 4235 | 1058.8 | 105.9 | 26.5 | An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. | Joseph A Maldjian, Paul J Laurienti, Robert A Kraft, Jonathan H Burdette | Neuroimage | 2003 | 12880848 | Yes |
3798 | 2117 | 1058.5 | 79.39 | 39.7 | A psychomotor stimulant theory of addiction. | R A Wise, M A Bozarth | Psychol Rev | 1987 | 3317472 | No |
3799 | 1058 | 1058.0 | 43.27 | 43.3 | Movement, posture and equilibrium: interaction and coordination. | J Massion | Prog Neurobiol | 1992 | 1736324 | No |
3800 | 2116 | 1058.0 | 45.3 | 22.6 | The immunoglobulin superfamily--domains for cell surface recognition. | A F Williams, A N Barclay | Annu Rev Immunol | 1988 | 3289571 | No |
3801 | 1058 | 1058.0 | 34.68 | 34.7 | Perceptual load as a necessary condition for selective attention. | N Lavie | J Exp Psychol Hum Percept Perform | 1995 | 7790827 | Yes |
3802 | 1058 | 1058.0 | 22.77 | 22.8 | Ligand-targeted therapeutics in anticancer therapy. | Theresa M Allen | Nat Rev Cancer | 2002 | 12360278 | No |
3803 | 1058 | 1058.0 | 29.81 | 29.8 | Micellar nanocarriers: pharmaceutical perspectives. | V P Torchilin | Pharm Res | 2007 | 17109211 | No |
3804 | 1058 | 1058.0 | 142.75 | 142.8 | COVID-19 Vaccine Hesitancy Worldwide: A Concise Systematic Review of Vaccine Acceptance Rates. | Malik Sallam | Vaccines (Basel) | 2021 | 33669441 | No |
3805 | 2115 | 1057.5 | 43.04 | 21.5 | Modified reagents for determination of urea and ammonia. | A L Chaney, E P Marbach | Clin Chem | 1962 | 13878063 | Yes |
3806 | 1057 | 1057.0 | 74.02 | 74.0 | Root canal anatomy of the human permanent teeth. | F J Vertucci | Oral Surg Oral Med Oral Pathol | 1984 | 6595621 | Yes |
3807 | 3171 | 1057.0 | 76.04 | 25.3 | Nitric oxide and macrophage function. | J MacMicking, Q W Xie, C Nathan | Annu Rev Immunol | 1997 | 9143691 | No |
3808 | 1057 | 1057.0 | 26.67 | 26.7 | The potential environmental impact of engineered nanomaterials. | Vicki L Colvin | Nat Biotechnol | 2003 | 14520401 | Yes |
3809 | 1057 | 1057.0 | 0.0 | 0.0 | Neural basis of the spontaneous optokinetic response produced by visual inversion. | R W Sperry | J Comp Physiol Psychol | 1950 | 14794830 | Yes |
3810 | 1057 | 1057.0 | 22.96 | 23.0 | Serine/threonine phosphatases: mechanism through structure. | Yigong Shi | Cell | 2009 | 19879837 | No |
3811 | 3171 | 1057.0 | 118.2 | 39.4 | Stimuli-responsive nanocarriers for drug delivery. | Simona Mura, Julien Nicolas, Patrick Couvreur | Nat Mater | 2013 | 24150417 | No |
3812 | 2113 | 1056.5 | 82.12 | 41.1 | Comparative aspects of the brain growth spurt. | J Dobbing, J Sands | Early Hum Dev | 1979 | 118862 | Yes |
3813 | 2112 | 1056.0 | 69.02 | 34.5 | Polymyositis and dermatomyositis (second of two parts). | A Bohan, J B Peter | N Engl J Med | 1975 | 1089199 | No |
3814 | 2112 | 1056.0 | 80.07 | 40.0 | Societal and individual determinants of medical care utilization in the United States. | R Andersen, J F Newman | Milbank Mem Fund Q Health Soc | 1973 | 4198894 | Yes |
3815 | 1056 | 1056.0 | 28.45 | 28.4 | T-cell growth factor. | K A Smith | Immunol Rev | 1980 | 7000676 | No |
3816 | 1056 | 1056.0 | 24.47 | 24.5 | Biochemistry and genetics of von Willebrand factor. | J E Sadler | Annu Rev Biochem | 1998 | 9759493 | No |
Download as CSV