Unicorn Papers
Top ‱ cited papers from PUBMED
Unicorn Papers are based on an equal contribution (EC) citation model in which the total number of citations had been divided by the number of the authorsCurrently, the list contains 3299 papers with ECcit ≥ 778.0
‱ - permyriad,
, literally meaning "for (every) myriad (ten thousand)"
Volume 2, October 2020
| No. | Citations | ECcit | RCR | ECRCR | Title | Authors | Journal | Year | PMID | Article(?) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 159932 | 159932.0 | 0.0 | 0.0 | Cleavage of structural proteins during the assembly of the head of bacteriophage T4. | U K Laemmli | Nature | 1970 | 5432063 | Yes |
| 2 | 129141 | 129141.0 | 0.0 | 0.0 | A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. | M M Bradford | Anal. Biochem. | 1976 | 942051 | Yes |
| 3 | 190774 | 47693.5 | 0.0 | 0.0 | Protein measurement with the Folin phenol reagent. | O H LOWRY, N J ROSEBROUGH, A L FARR, R J RANDALL | J. Biol. Chem. | 1951 | 14907713 | Yes |
| 4 | 38676 | 38676.0 | 1546.39 | 1546.4 | A short history of SHELX. | George M Sheldrick | Acta Crystallogr., A, Found. Crystallogr. | 2008 | 18156677 | Yes |
| 5 | 73121 | 36560.5 | 2096.5 | 1048.2 | Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. | K J Livak, T D Schmittgen | Methods | 2001 | 11846609 | Yes |
| 6 | 24924 | 24924.0 | 1042.65 | 1042.7 | Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. | T Mosmann | J. Immunol. Methods | 1983 | 6606682 | Yes |
| 7 | 22896 | 22896.0 | 0.0 | 0.0 | Detection of specific sequences among DNA fragments separated by gel electrophoresis. | E M Southern | J. Mol. Biol. | 1975 | 1195397 | Yes |
| 8 | 45159 | 22579.5 | 1853.24 | 926.6 | Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. | P Chomczynski, N Sacchi | Anal. Biochem. | 1987 | 2440339 | Yes |
| 9 | 20494 | 20494.0 | 0.0 | 0.0 | The assessment and analysis of handedness: the Edinburgh inventory. | R C Oldfield | Neuropsychologia | 1971 | 5146491 | Yes |
| 10 | 20355 | 20355.0 | 506.03 | 506.0 | MicroRNAs: genomics, biogenesis, mechanism, and function. | David P Bartel | Cell | 2004 | 14744438 | No |
| 11 | 17696 | 17696.0 | 463.68 | 463.7 | A new mathematical model for relative quantification in real-time RT-PCR. | M W Pfaffl | Nucleic Acids Res. | 2001 | 11328886 | Yes |
| 12 | 17396 | 17396.0 | 471.24 | 471.2 | MUSCLE: multiple sequence alignment with high accuracy and high throughput. | Robert C Edgar | Nucleic Acids Res. | 2004 | 15034147 | Yes |
| 13 | 16591 | 16591.0 | 0.0 | 0.0 | A rating scale for depression. | M HAMILTON | J. Neurol. Neurosurg. Psychiatry | 1960 | 14399272 | Yes |
| 14 | 45901 | 15300.3 | 0.0 | 0.0 | "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. | M F Folstein, S E Folstein, P R McHugh | J Psychiatr Res | 1975 | 1202204 | Yes |
| 15 | 30084 | 15042.0 | 1132.15 | 566.1 | The neighbor-joining method: a new method for reconstructing phylogenetic trees. | N Saitou, M Nei | Mol. Biol. Evol. | 1987 | 3447015 | Yes |
| 16 | 44632 | 14877.3 | 0.0 | 0.0 | DNA sequencing with chain-terminating inhibitors. | F Sanger, S Nicklen, A R Coulson | Proc. Natl. Acad. Sci. U.S.A. | 1977 | 271968 | Yes |
| 17 | 13875 | 13875.0 | 0.0 | 0.0 | The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. | E S REYNOLDS | J. Cell Biol. | 1963 | 13986422 | Yes |
| 18 | 26787 | 13393.5 | 1629.9 | 815.0 | Statistical methods for assessing agreement between two methods of clinical measurement. | J M Bland, D G Altman | Lancet | 1986 | 2868172 | Yes |
| 19 | 13235 | 13235.0 | 405.1 | 405.1 | Atherosclerosis--an inflammatory disease. | R Ross | N. Engl. J. Med. | 1999 | 9887164 | No |
| 20 | 12483 | 12483.0 | 558.66 | 558.7 | A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences. | M Kimura | J. Mol. Evol. | 1980 | 7463489 | Yes |
| 21 | 12455 | 12455.0 | 0.0 | 0.0 | Tissue sulfhydryl groups. | G L ELLMAN | Arch. Biochem. Biophys. | 1959 | 13650640 | Yes |
| 22 | 36844 | 12281.3 | 1258.16 | 419.4 | CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. | J D Thompson, D G Higgins, T J Gibson | Nucleic Acids Res. | 1994 | 7984417 | Yes |
| 23 | 24559 | 12279.5 | 0.0 | 0.0 | The measurement of observer agreement for categorical data. | J R Landis, G G Koch | Biometrics | 1977 | 843571 | Yes |
| 24 | 24272 | 12136.0 | 1006.78 | 503.4 | Hallmarks of cancer: the next generation. | Douglas Hanahan, Robert A Weinberg | Cell | 2011 | 21376230 | No |
| 25 | 12023 | 12023.0 | 536.74 | 536.7 | Density-functional exchange-energy approximation with correct asymptotic behavior. | Becke | Phys Rev A Gen Phys | 1988 | 9900728 | Yes |
| 26 | 34937 | 11645.7 | 0.0 | 0.0 | Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. | H Towbin, T Staehelin, J Gordon | Proc. Natl. Acad. Sci. U.S.A. | 1979 | 388439 | Yes |
| 27 | 11614 | 11614.0 | 442.4 | 442.4 | CONFIDENCE LIMITS ON PHYLOGENIES: AN APPROACH USING THE BOOTSTRAP. | Joseph Felsenstein | Evolution | 1985 | 28561359 | Yes |
| 28 | 11592 | 11592.0 | 0.0 | 0.0 | High resolution two-dimensional electrophoresis of proteins. | P H O'Farrell | J. Biol. Chem. | 1975 | 236308 | Yes |
| 29 | 10986 | 10986.0 | 332.77 | 332.8 | MicroRNAs: target recognition and regulatory functions. | David P Bartel | Cell | 2009 | 19167326 | No |
| 30 | 21361 | 10680.5 | 0.0 | 0.0 | A rapid method of total lipid extraction and purification. | E G BLIGH, W J DYER | Can J Biochem Physiol | 1959 | 13671378 | Yes |
| 31 | 10369 | 10369.0 | 552.05 | 552.0 | A power primer. | J Cohen | Psychol Bull | 1992 | 19565683 | Yes |
| 32 | 10216 | 10216.0 | 0.0 | 0.0 | DISC ELECTROPHORESIS. II. METHOD AND APPLICATION TO HUMAN SERUM PROTEINS. | B J DAVIS | Ann. N. Y. Acad. Sci. | 1964 | 14240539 | Yes |
| 33 | 20313 | 10156.5 | 936.93 | 468.5 | Meta-analysis in clinical trials. | R DerSimonian, N Laird | Control Clin Trials | 1986 | 3802833 | Yes |
| 34 | 19551 | 9775.5 | 1012.57 | 506.3 | The hospital anxiety and depression scale. | A S Zigmond, R P Snaith | Acta Psychiatr Scand | 1983 | 6880820 | Yes |
| 35 | 9706 | 9706.0 | 0.0 | 0.0 | A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. | K BURTON | Biochem. J. | 1956 | 13293190 | Yes |
| 36 | 28903 | 9634.3 | 0.0 | 0.0 | A simple method for the isolation and purification of total lipides from animal tissues. | J FOLCH, M LEES, G H SLOANE STANLEY | J. Biol. Chem. | 1957 | 13428781 | Yes |
| 37 | 9303 | 9303.0 | 307.15 | 307.1 | Projector augmented-wave method. | Blöchl | Phys. Rev., B Condens. Matter | 1994 | 9976227 | Yes |
| 38 | 18456 | 9228.0 | 1019.17 | 509.6 | The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. | J E Ware, C D Sherbourne | Med Care | 1992 | 1593914 | Yes |
| 39 | 9223 | 9223.0 | 445.99 | 446.0 | Structure validation in chemical crystallography. | Anthony L Spek | Acta Crystallogr. D Biol. Crystallogr. | 2009 | 19171970 | Yes |
| 40 | 18107 | 9053.5 | 440.82 | 220.4 | Coot: model-building tools for molecular graphics. | Paul Emsley, Kevin Cowtan | Acta Crystallogr. D Biol. Crystallogr. | 2004 | 15572765 | Yes |
| 41 | 42972 | 8594.4 | 1465.14 | 293.0 | Basic local alignment search tool. | S F Altschul, W Gish, W Miller, E W Myers, D J Lipman | J. Mol. Biol. | 1990 | 2231712 | Yes |
| 42 | 8591 | 8591.0 | 428.58 | 428.6 | Catalase in vitro. | H Aebi | Meth. Enzymol. | 1984 | 6727660 | Yes |
| 43 | 8510 | 8510.0 | 0.0 | 0.0 | The genetics of Caenorhabditis elegans. | S Brenner | Genetics | 1974 | 4366476 | Yes |
| 44 | 8371 | 8371.0 | 0.0 | 0.0 | Phosphorus assay in column chromatography. | G R BARTLETT | J. Biol. Chem. | 1959 | 13641241 | Yes |
| 45 | 24178 | 8059.3 | 863.31 | 287.8 | Generalized Gradient Approximation Made Simple. | Perdew, Burke, Ernzerhof | Phys. Rev. Lett. | 1996 | 10062328 | Yes |
| 46 | 7959 | 7959.0 | 274.57 | 274.6 | The Psychophysics Toolbox. | D H Brainard | Spat Vis | 1997 | 9176952 | Yes |
| 47 | 15716 | 7858.0 | 475.18 | 237.6 | Fast and accurate short read alignment with Burrows-Wheeler transform. | Heng Li, Richard Durbin | Bioinformatics | 2009 | 19451168 | Yes |
| 48 | 15498 | 7749.0 | 580.81 | 290.4 | A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. | A P Feinberg, B Vogelstein | Anal. Biochem. | 1983 | 6312838 | Yes |
| 49 | 7643 | 7643.0 | 324.47 | 324.5 | Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). | J F Kurtzke | Neurology | 1983 | 6685237 | Yes |
| 50 | 15158 | 7579.0 | 373.89 | 186.9 | [20] Processing of X-ray diffraction data collected in oscillation mode. | Zbyszek Otwinowski, Wladek Minor | Meth. Enzymol. | 1997 | 27799103 | Yes |
| 51 | 7508 | 7508.0 | 248.55 | 248.6 | XDS. | Wolfgang Kabsch | Acta Crystallogr. D Biol. Crystallogr. | 2010 | 20124692 | Yes |
| 52 | 7500 | 7500.0 | 264.31 | 264.3 | Studies on transformation of Escherichia coli with plasmids. | D Hanahan | J. Mol. Biol. | 1983 | 6345791 | Yes |
| 53 | 7439 | 7439.0 | 179.32 | 179.3 | Mfold web server for nucleic acid folding and hybridization prediction. | Michael Zuker | Nucleic Acids Res. | 2003 | 12824337 | Yes |
| 54 | 7403 | 7403.0 | 170.01 | 170.0 | Linear models and empirical bayes methods for assessing differential expression in microarray experiments. | Gordon K Smyth | Stat Appl Genet Mol Biol | 2004 | 16646809 | Yes |
| 55 | 7385 | 7385.0 | 308.28 | 308.3 | Search and clustering orders of magnitude faster than BLAST. | Robert C Edgar | Bioinformatics | 2010 | 20709691 | Yes |
| 56 | 7331 | 7331.0 | 0.0 | 0.0 | Self-efficacy: toward a unifying theory of behavioral change. | A Bandura | Psychol Rev | 1977 | 847061 | Yes |
| 57 | 21862 | 7287.3 | 1001.12 | 333.7 | Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density. | Lee, Yang, Parr | Phys. Rev., B Condens. Matter | 1988 | 9944570 | Yes |
| 58 | 14485 | 7242.5 | 796.02 | 398.0 | The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. | R M Baron, D A Kenny | J Pers Soc Psychol | 1986 | 3806354 | Yes |
| 59 | 7214 | 7214.0 | 218.56 | 218.6 | RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. | Alexandros Stamatakis | Bioinformatics | 2006 | 16928733 | Yes |
| 60 | 7082 | 7082.0 | 245.96 | 246.0 | Evolutionary trees from DNA sequences: a maximum likelihood approach. | J Felsenstein | J. Mol. Evol. | 1981 | 7288891 | Yes |
| 61 | 7072 | 7072.0 | 473.07 | 473.1 | RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies. | Alexandros Stamatakis | Bioinformatics | 2014 | 24451623 | Yes |
| 62 | 14129 | 7064.5 | 344.28 | 172.1 | The hallmarks of cancer. | D Hanahan, R A Weinberg | Cell | 2000 | 10647931 | No |
| 63 | 7040 | 7040.0 | 261.83 | 261.8 | The pathogenesis of atherosclerosis: a perspective for the 1990s. | R Ross | Nature | 1993 | 8479518 | No |
| 64 | 7032 | 7032.0 | 340.01 | 340.0 | A new method for measuring daytime sleepiness: the Epworth sleepiness scale. | M W Johns | Sleep | 1991 | 1798888 | Yes |
| 65 | 13987 | 6993.5 | 489.95 | 245.0 | A simple method for displaying the hydropathic character of a protein. | J Kyte, R F Doolittle | J. Mol. Biol. | 1982 | 7108955 | Yes |
| 66 | 6746 | 6746.0 | 0.0 | 0.0 | Improvements in epoxy resin embedding methods. | J H LUFT | J Biophys Biochem Cytol | 1961 | 13764136 | Yes |
| 67 | 6669 | 6669.0 | 245.04 | 245.0 | Vitamin D deficiency. | Michael F Holick | N. Engl. J. Med. | 2007 | 17634462 | No |
| 68 | 13153 | 6576.5 | 439.8 | 219.9 | Quantifying heterogeneity in a meta-analysis. | Julian P T Higgins, Simon G Thompson | Stat Med | 2002 | 12111919 | Yes |
| 69 | 6515 | 6515.0 | 220.73 | 220.7 | Integrins: versatility, modulation, and signaling in cell adhesion. | R O Hynes | Cell | 1992 | 1555235 | No |
| 70 | 12863 | 6431.5 | 0.0 | 0.0 | The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. | K Weber, M Osborn | J. Biol. Chem. | 1969 | 5806584 | Yes |
| 71 | 12840 | 6420.0 | 545.44 | 272.7 | Fast gapped-read alignment with Bowtie 2. | Ben Langmead, Steven L Salzberg | Nat. Methods | 2012 | 22388286 | Yes |
| 72 | 6370 | 6370.0 | 150.63 | 150.6 | The functions of animal microRNAs. | Victor Ambros | Nature | 2004 | 15372042 | No |
| 73 | 6341 | 6341.0 | 275.7 | 275.7 | Banting lecture 1988. Role of insulin resistance in human disease. | G M Reaven | Diabetes | 1988 | 3056758 | No |
| 74 | 6286 | 6286.0 | 365.93 | 365.9 | Psychophysical bases of perceived exertion. | G A Borg | Med Sci Sports Exerc | 1982 | 7154893 | Yes |
| 75 | 12405 | 6202.5 | 314.62 | 157.3 | Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. | Kazutoshi Takahashi, Shinya Yamanaka | Cell | 2006 | 16904174 | Yes |
| 76 | 6107 | 6107.0 | 199.96 | 200.0 | TreeView: an application to display phylogenetic trees on personal computers. | R D Page | Comput. Appl. Biosci. | 1996 | 8902363 | Yes |
| 77 | 6100 | 6100.0 | 0.0 | 0.0 | On the origin of cancer cells. | O WARBURG | Science | 1956 | 13298683 | Yes |
| 78 | 12124 | 6062.0 | 343.35 | 171.7 | MrBayes 3: Bayesian phylogenetic inference under mixed models. | Fredrik Ronquist, John P Huelsenbeck | Bioinformatics | 2003 | 12912839 | Yes |
| 79 | 6031 | 6031.0 | 0.0 | 0.0 | COPPER ENZYMES IN ISOLATED CHLOROPLASTS. POLYPHENOLOXIDASE IN BETA VULGARIS. | D I Arnon | Plant Physiol. | 1949 | 16654194 | Yes |
| 80 | 6026 | 6026.0 | 187.34 | 187.3 | Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. | M C Hochberg | Arthritis Rheum. | 1997 | 9324032 | Yes |
| 81 | 42008 | 6001.1 | 1255.48 | 179.4 | Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. | S F Altschul, T L Madden, A A Schäffer, J Zhang, Z Zhang, W Miller, D J Lipman | Nucleic Acids Res. | 1997 | 9254694 | No |
| 82 | 11930 | 5965.0 | 381.74 | 190.9 | Efficient iterative schemes for ab initio total-energy calculations using a plane-wave basis set. | Kresse, Furthmüller | Phys. Rev., B Condens. Matter | 1996 | 9984901 | Yes |
| 83 | 5960 | 5960.0 | 182.21 | 182.2 | Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. | F Tajima | Genetics | 1989 | 2513255 | Yes |
| 84 | 23815 | 5953.8 | 853.81 | 213.5 | Measuring inconsistency in meta-analyses. | Julian P T Higgins, Simon G Thompson, Jonathan J Deeks, Douglas G Altman | BMJ | 2003 | 12958120 | No |
| 85 | 17429 | 5809.7 | 544.33 | 181.4 | Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. | Da Wei Huang, Brad T Sherman, Richard A Lempicki | Nat Protoc | 2009 | 19131956 | Yes |
| 86 | 5805 | 5805.0 | 242.46 | 242.5 | Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. | P S Thomas | Proc. Natl. Acad. Sci. U.S.A. | 1980 | 6159641 | Yes |
| 87 | 5752 | 5752.0 | 196.38 | 196.4 | Semiempirical GGA-type density functional constructed with a long-range dispersion correction. | Stefan Grimme | J Comput Chem | 2006 | 16955487 | Yes |
| 88 | 5751 | 5751.0 | 196.96 | 197.0 | AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. | R W Cox | Comput. Biomed. Res. | 1996 | 8812068 | Yes |
| 89 | 17245 | 5748.3 | 505.69 | 168.6 | VMD: visual molecular dynamics. | W Humphrey, A Dalke, K Schulten | J Mol Graph | 1996 | 8744570 | Yes |
| 90 | 5700 | 5700.0 | 562.06 | 562.1 | Crystal structure refinement with SHELXL. | George M Sheldrick | Acta Crystallogr C Struct Chem | 2015 | 25567568 | Yes |
| 91 | 5687 | 5687.0 | 141.13 | 141.1 | Chromatin modifications and their function. | Tony Kouzarides | Cell | 2007 | 17320507 | No |
| 92 | 11339 | 5669.5 | 275.43 | 137.7 | Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana. | S J Clough, A F Bent | Plant J. | 1998 | 10069079 | Yes |
| 93 | 22512 | 5628.0 | 1038.82 | 259.7 | A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. | M E Charlson, P Pompei, K L Ales, C R MacKenzie | J Chronic Dis | 1987 | 3558716 | Yes |
| 94 | 5567 | 5567.0 | 222.28 | 222.3 | "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. | W N Burnette | Anal. Biochem. | 1981 | 6266278 | Yes |
| 95 | 5515 | 5515.0 | 156.51 | 156.5 | PAML 4: phylogenetic analysis by maximum likelihood. | Ziheng Yang | Mol. Biol. Evol. | 2007 | 17483113 | Yes |
| 96 | 5491 | 5491.0 | 0.0 | 0.0 | A simplification of the protein assay method of Lowry et al. which is more generally applicable. | G L Peterson | Anal. Biochem. | 1977 | 603028 | Yes |
| 97 | 5406 | 5406.0 | 0.0 | 0.0 | Solvent content of protein crystals. | B W Matthews | J. Mol. Biol. | 1968 | 5700707 | Yes |
| 98 | 10685 | 5342.5 | 413.52 | 206.8 | Sequencing end-labeled DNA with base-specific chemical cleavages. | A M Maxam, W Gilbert | Meth. Enzymol. | 1980 | 6246368 | Yes |
| 99 | 5331 | 5331.0 | 157.16 | 157.2 | Fast robust automated brain extraction. | Stephen M Smith | Hum Brain Mapp | 2002 | 12391568 | No |
| 100 | 21288 | 5322.0 | 833.43 | 208.4 | Bias in meta-analysis detected by a simple, graphical test. | M Egger, G Davey Smith, M Schneider, C Minder | BMJ | 1997 | 9310563 | Yes |
| 101 | 5279 | 5279.0 | 183.56 | 183.6 | The VideoToolbox software for visual psychophysics: transforming numbers into movies. | D G Pelli | Spat Vis | 1997 | 9176953 | Yes |
| 102 | 10458 | 5229.0 | 330.61 | 165.3 | Analyzing real-time PCR data by the comparative C(T) method. | Thomas D Schmittgen, Kenneth J Livak | Nat Protoc | 2008 | 18546601 | Yes |
| 103 | 15685 | 5228.3 | 0.0 | 0.0 | Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. | W T Friedewald, R I Levy, D S Fredrickson | Clin. Chem. | 1972 | 4337382 | Yes |
| 104 | 5194 | 5194.0 | 0.0 | 0.0 | A low-viscosity epoxy resin embedding medium for electron microscopy. | A R Spurr | J. Ultrastruct. Res. | 1969 | 4887011 | Yes |
| 105 | 5163 | 5163.0 | 217.13 | 217.1 | Ethical guidelines for investigations of experimental pain in conscious animals. | M Zimmermann | Pain | 1983 | 6877845 | No |
| 106 | 15263 | 5087.7 | 579.2 | 193.1 | A new generation of Ca2+ indicators with greatly improved fluorescence properties. | G Grynkiewicz, M Poenie, R Y Tsien | J. Biol. Chem. | 1985 | 3838314 | Yes |
| 107 | 5040 | 5040.0 | 0.0 | 0.0 | Evaluation of survival data and two new rank order statistics arising in its consideration. | N Mantel | Cancer Chemother Rep | 1966 | 5910392 | Yes |
| 108 | 4977 | 4977.0 | 308.55 | 308.6 | Comparative fit indexes in structural models. | P M Bentler | Psychol Bull | 1990 | 2320703 | Yes |
| 109 | 4967 | 4967.0 | 204.34 | 204.3 | The role of protein kinase C in cell surface signal transduction and tumour promotion. | Y Nishizuka | Nature | 1984 | 6232463 | No |
| 110 | 4910 | 4910.0 | 165.64 | 165.6 | Canonical dynamics: Equilibrium phase-space distributions. | Hoover | Phys Rev A Gen Phys | 1985 | 9895674 | Yes |
| 111 | 4890 | 4890.0 | 112.16 | 112.2 | Integrins: bidirectional, allosteric signaling machines. | Richard O Hynes | Cell | 2002 | 12297042 | No |
| 112 | 9728 | 4864.0 | 0.0 | 0.0 | A rapid alkaline extraction procedure for screening recombinant plasmid DNA. | H C Birnboim, J Doly | Nucleic Acids Res. | 1979 | 388356 | Yes |
| 113 | 4836 | 4836.0 | 152.42 | 152.4 | Angiogenesis in cancer, vascular, rheumatoid and other disease. | J Folkman | Nat. Med. | 1995 | 7584949 | No |
| 114 | 4814 | 4814.0 | 209.65 | 209.7 | Density-functional approximation for the correlation energy of the inhomogeneous electron gas. | Perdew | Phys. Rev., B Condens. Matter | 1986 | 9938299 | Yes |
| 115 | 4809 | 4809.0 | 125.76 | 125.8 | Inflammation in atherosclerosis. | Peter Libby | Nature | 2002 | 12490960 | No |
| 116 | 4794 | 4794.0 | 0.0 | 0.0 | Tumor angiogenesis: therapeutic implications. | J Folkman | N. Engl. J. Med. | 1971 | 4938153 | No |
| 117 | 4742 | 4742.0 | 118.7 | 118.7 | p53, the cellular gatekeeper for growth and division. | A J Levine | Cell | 1997 | 9039259 | No |
| 118 | 14198 | 4732.7 | 655.59 | 218.5 | NIH Image to ImageJ: 25 years of image analysis. | Caroline A Schneider, Wayne S Rasband, Kevin W Eliceiri | Nat. Methods | 2012 | 22930834 | No |
| 119 | 4726 | 4726.0 | 0.0 | 0.0 | Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. | J R Vane | Nature New Biol. | 1971 | 5284360 | Yes |
| 120 | 4724 | 4724.0 | 188.01 | 188.0 | The blockade of immune checkpoints in cancer immunotherapy. | Drew M Pardoll | Nat. Rev. Cancer | 2012 | 22437870 | No |
| 121 | 4686 | 4686.0 | 133.71 | 133.7 | Inflammation, atherosclerosis, and coronary artery disease. | Göran K Hansson | N. Engl. J. Med. | 2005 | 15843671 | No |
| 122 | 9303 | 4651.5 | 307.86 | 153.9 | MODELTEST: testing the model of DNA substitution. | D Posada, K A Crandall | Bioinformatics | 1998 | 9918953 | Yes |
| 123 | 4650 | 4650.0 | 185.95 | 185.9 | The Clinical Dementia Rating (CDR): current version and scoring rules. | J C Morris | Neurology | 1993 | 8232972 | Yes |
| 124 | 9298 | 4649.0 | 0.0 | 0.0 | Intraclass correlations: uses in assessing rater reliability. | P E Shrout, J L Fleiss | Psychol Bull | 1979 | 18839484 | No |
| 125 | 9232 | 4616.0 | 249.25 | 124.6 | A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. | Stéphane Guindon, Olivier Gascuel | Syst. Biol. | 2003 | 14530136 | Yes |
| 126 | 4613 | 4613.0 | 0.0 | 0.0 | Development of a rating scale for primary depressive illness. | M Hamilton | Br J Soc Clin Psychol | 1967 | 6080235 | Yes |
| 127 | 4606 | 4606.0 | 130.88 | 130.9 | Biochemistry and molecular cell biology of diabetic complications. | M Brownlee | Nature | 2001 | 11742414 | Yes |
| 128 | 9190 | 4595.0 | 258.6 | 129.3 | MRBAYES: Bayesian inference of phylogenetic trees. | J P Huelsenbeck, F Ronquist | Bioinformatics | 2001 | 11524383 | Yes |
| 129 | 9189 | 4594.5 | 236.55 | 118.3 | Dendritic cells and the control of immunity. | J Banchereau, R M Steinman | Nature | 1998 | 9521319 | No |
| 130 | 9106 | 4553.0 | 0.0 | 0.0 | Statistical aspects of the analysis of data from retrospective studies of disease. | N MANTEL, W HAENSZEL | J. Natl. Cancer Inst. | 1959 | 13655060 | Yes |
| 131 | 4544 | 4544.0 | 137.19 | 137.2 | Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. | T A Springer | Cell | 1994 | 7507411 | No |
| 132 | 22694 | 4538.8 | 721.6 | 144.3 | The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. | J D Thompson, T J Gibson, F Plewniak, F Jeanmougin, D G Higgins | Nucleic Acids Res. | 1997 | 9396791 | Yes |
| 133 | 9026 | 4513.0 | 0.0 | 0.0 | Prediction of creatinine clearance from serum creatinine. | D W Cockcroft, M H Gault | Nephron | 1976 | 1244564 | Yes |
| 134 | 9016 | 4508.0 | 208.87 | 104.4 | KEGG: kyoto encyclopedia of genes and genomes. | M Kanehisa, S Goto | Nucleic Acids Res. | 2000 | 10592173 | Yes |
| 135 | 4486 | 4486.0 | 146.32 | 146.3 | Inositol trisphosphate and calcium signalling. | M J Berridge | Nature | 1993 | 8381210 | No |
| 136 | 4480 | 4480.0 | 92.19 | 92.2 | BLAT--the BLAST-like alignment tool. | W James Kent | Genome Res. | 2002 | 11932250 | Yes |
| 137 | 8923 | 4461.5 | 0.0 | 0.0 | Continuous cultures of fused cells secreting antibody of predefined specificity. | G Köhler, C Milstein | Nature | 1975 | 1172191 | Yes |
| 138 | 4430 | 4430.0 | 159.31 | 159.3 | The steroid and thyroid hormone receptor superfamily. | R M Evans | Science | 1988 | 3283939 | No |
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| 3278 | 782 | 782.0 | 36.31 | 36.3 | Comfortable and maximum walking speed of adults aged 20-79 years: reference values and determinants. | R W Bohannon | Age Ageing | 1997 | 9143432 | Yes |
| 3279 | 782 | 782.0 | 21.71 | 21.7 | Biochemistry and genetics of von Willebrand factor. | J E Sadler | Annu. Rev. Biochem. | 1998 | 9759493 | No |
| 3280 | 782 | 782.0 | 0.0 | 0.0 | Biochemistry of dystrophic muscle. Mitochondrial succinate-tetrazolium reductase and adenosine triphosphatase. | R J PENNINGTON | Biochem. J. | 1961 | 13734134 | Yes |
| 3281 | 782 | 782.0 | 0.0 | 0.0 | Aerobic work capacity in men and women with special reference to age. | I ASTRAND | Acta Physiol Scand Suppl | 1960 | 13794892 | Yes |
| 3282 | 3127 | 781.8 | 0.0 | 0.0 | Characteristics of a human cell line transformed by DNA from human adenovirus type 5. | F L Graham, J Smiley, W C Russell, R Nairn | J. Gen. Virol. | 1977 | 886304 | Yes |
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| 3285 | 781 | 781.0 | 14.04 | 14.0 | Protein regulation by monoubiquitin. | L Hicke | Nat. Rev. Mol. Cell Biol. | 2001 | 11265249 | No |
| 3286 | 781 | 781.0 | 15.02 | 15.0 | Molecular dissection of autophagy: two ubiquitin-like systems. | Y Ohsumi | Nat. Rev. Mol. Cell Biol. | 2001 | 11265251 | No |
| 3287 | 781 | 781.0 | 24.69 | 24.7 | The emotional dog and its rational tail: a social intuitionist approach to moral judgment. | J Haidt | Psychol Rev | 2001 | 11699120 | Yes |
| 3288 | 780 | 780.0 | 61.87 | 61.9 | The stabilizing system of the spine. Part I. Function, dysfunction, adaptation, and enhancement. | M M Panjabi | J Spinal Disord | 1992 | 1490034 | Yes |
| 3289 | 2340 | 780.0 | 62.62 | 20.9 | Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. | P Tontonoz, E Hu, B M Spiegelman | Cell | 1994 | 8001151 | Yes |
| 3290 | 1560 | 780.0 | 44.29 | 22.1 | Quorum sensing: cell-to-cell communication in bacteria. | Christopher M Waters, Bonnie L Bassler | Annu. Rev. Cell Dev. Biol. | 2005 | 16212498 | No |
| 3291 | 5460 | 780.0 | 236.26 | 33.8 | GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. | Gordon H Guyatt, Andrew D Oxman, Gunn E Vist, Regina Kunz, Yngve Falck-Ytter, Pablo Alonso-Coello, Holger J Schünemann | BMJ | 2008 | 18436948 | Yes |
| 3292 | 2337 | 779.0 | 130.12 | 43.4 | Measurement of health status. Ascertaining the minimal clinically important difference. | R Jaeschke, J Singer, G H Guyatt | Control Clin Trials | 1989 | 2691207 | Yes |
| 3293 | 779 | 779.0 | 40.84 | 40.8 | Gait changes in older adults: predictors of falls or indicators of fear. | B E Maki | J Am Geriatr Soc | 1997 | 9063277 | Yes |
| 3294 | 3116 | 779.0 | 104.09 | 26.0 | Biological identifications through DNA barcodes. | Paul D N Hebert, Alina Cywinska, Shelley L Ball, Jeremy R deWaard | Proc. Biol. Sci. | 2003 | 12614582 | Yes |
| 3295 | 779 | 779.0 | 24.69 | 24.7 | TNF-mediated inflammatory disease. | J R Bradley | J. Pathol. | 2008 | 18161752 | No |
| 3296 | 779 | 779.0 | 25.77 | 25.8 | Neuronal gamma-band synchronization as a fundamental process in cortical computation. | Pascal Fries | Annu. Rev. Neurosci. | 2009 | 19400723 | No |
| 3297 | 5451 | 778.7 | 262.74 | 37.5 | Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. | F C Tenover, R D Arbeit, R V Goering, P A Mickelsen, B E Murray, D H Persing, B Swaminathan | J. Clin. Microbiol. | 1995 | 7494007 | No |
| 3298 | 1557 | 778.5 | 59.43 | 29.7 | Nitric oxide synthases in mammals. | R G Knowles, S Moncada | Biochem. J. | 1994 | 7510950 | No |
| 3299 | 1556 | 778.0 | 44.92 | 22.5 | Cellular uptake of the tat protein from human immunodeficiency virus. | A D Frankel, C O Pabo | Cell | 1988 | 2849510 | Yes |
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