Unicorn Papers
Top ‱ cited papers from PUBMED
Unicorn Papers are based on an equal contribution (EC) citation model in which the total number of citations had been divided by the number of the authorsCurrently, the list contains 3523 papers with ECcit ≥ 1006.0
‱ - permyriad,
, literally meaning "for (every) myriad (ten thousand)"
Volume 19, March 2022
| No. | Citations | ECcit | RCR | ECRCR | Title | Authors | Journal | Year | PMID | Article(?) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 222053 | 222053.0 | 0.0 | 0.0 | Cleavage of structural proteins during the assembly of the head of bacteriophage T4. | U K Laemmli | Nature | 1970 | 5432063 | Yes |
| 2 | 169006 | 169006.0 | 0.0 | 0.0 | A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. | M M Bradford | Anal Biochem | 1976 | 942051 | Yes |
| 3 | 284733 | 71183.2 | 0.0 | 0.0 | Protein measurement with the Folin phenol reagent. | O H Lowry, N J Rosebrough, A L Farr, R J Randall | J Biol Chem | 1951 | 14907713 | Yes |
| 4 | 99949 | 49974.5 | 2563.71 | 1281.9 | Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. | K J Livak, T D Schmittgen | Methods | 2001 | 11846609 | Yes |
| 5 | 43302 | 43302.0 | 1442.14 | 1442.1 | A short history of SHELX. | George M Sheldrick | Acta Crystallogr A | 2008 | 18156677 | Yes |
| 6 | 34077 | 34077.0 | 1104.84 | 1104.8 | Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. | T Mosmann | J Immunol Methods | 1983 | 6606682 | Yes |
| 7 | 65118 | 32559.0 | 1973.3 | 986.6 | Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. | P Chomczynski, N Sacchi | Anal Biochem | 1987 | 2440339 | Yes |
| 8 | 30194 | 30194.0 | 0.0 | 0.0 | Detection of specific sequences among DNA fragments separated by gel electrophoresis. | E M Southern | J Mol Biol | 1975 | 1195397 | Yes |
| 9 | 25745 | 25745.0 | 0.0 | 0.0 | The assessment and analysis of handedness: the Edinburgh inventory. | R C Oldfield | Neuropsychologia | 1971 | 5146491 | Yes |
| 10 | 25394 | 25394.0 | 583.89 | 583.9 | MicroRNAs: genomics, biogenesis, mechanism, and function. | David P Bartel | Cell | 2004 | 14744438 | No |
| 11 | 23898 | 23898.0 | 0.0 | 0.0 | A rating scale for depression. | M Hamilton | J Neurol Neurosurg Psychiatry | 1960 | 14399272 | Yes |
| 12 | 22726 | 22726.0 | 713.16 | 713.2 | Confidence Limits On Phylogenies: An Approach Using The Bootstrap. | Joseph Felsenstein | Evolution | 1985 | 28561359 | Yes |
| 13 | 22279 | 22279.0 | 549.79 | 549.8 | MUSCLE: multiple sequence alignment with high accuracy and high throughput. | Robert C Edgar | Nucleic Acids Res | 2004 | 15034147 | Yes |
| 14 | 21895 | 21895.0 | 519.02 | 519.0 | A new mathematical model for relative quantification in real-time RT-PCR. | M W Pfaffl | Nucleic Acids Res | 2001 | 11328886 | Yes |
| 15 | 65451 | 21817.0 | 0.0 | 0.0 | DNA sequencing with chain-terminating inhibitors. | F Sanger, S Nicklen, A R Coulson | Proc Natl Acad Sci U S A | 1977 | 271968 | Yes |
| 16 | 61088 | 20362.7 | 0.0 | 0.0 | "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. | M F Folstein, S E Folstein, P R McHugh | J Psychiatr Res | 1975 | 1202204 | Yes |
| 17 | 20000 | 20000.0 | 0.0 | 0.0 | The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. | E S Reynolds | J Cell Biol | 1963 | 13986422 | Yes |
| 18 | 18631 | 18631.0 | 660.81 | 660.8 | Density-functional exchange-energy approximation with correct asymptotic behavior. | Becke | Phys Rev A Gen Phys | 1988 | 9900728 | Yes |
| 19 | 37232 | 18616.0 | 1155.56 | 577.8 | The neighbor-joining method: a new method for reconstructing phylogenetic trees. | N Saitou, M Nei | Mol Biol Evol | 1987 | 3447015 | Yes |
| 20 | 18319 | 18319.0 | 0.0 | 0.0 | Tissue sulfhydryl groups. | G L Ellman | Arch Biochem Biophys | 1959 | 13650640 | Yes |
| 21 | 53215 | 17738.3 | 0.0 | 0.0 | Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. | H Towbin, T Staehelin, J Gordon | Proc Natl Acad Sci U S A | 1979 | 388439 | Yes |
| 22 | 34046 | 17023.0 | 1189.3 | 594.6 | Hallmarks of cancer: the next generation. | Douglas Hanahan, Robert A Weinberg | Cell | 2011 | 21376230 | No |
| 23 | 33631 | 16815.5 | 1622.06 | 811.0 | Statistical methods for assessing agreement between two methods of clinical measurement. | J M Bland, D G Altman | Lancet | 1986 | 2868172 | Yes |
| 24 | 16804 | 16804.0 | 0.0 | 0.0 | Disc Electrophoresis. Ii. Method And Application To Human Serum Proteins. | B J Davis | Ann N Y Acad Sci | 1964 | 14240539 | Yes |
| 25 | 16251 | 16251.0 | 0.0 | 0.0 | High resolution two-dimensional electrophoresis of proteins. | P H O'Farrell | J Biol Chem | 1975 | 236308 | Yes |
| 26 | 16235 | 16235.0 | 420.76 | 420.8 | Atherosclerosis--an inflammatory disease. | R Ross | N Engl J Med | 1999 | 9887164 | No |
| 27 | 15904 | 15904.0 | 0.0 | 0.0 | A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. | K Burton | Biochem J | 1956 | 13293190 | Yes |
| 28 | 15646 | 15646.0 | 584.44 | 584.4 | A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences. | M Kimura | J Mol Evol | 1980 | 7463489 | Yes |
| 29 | 30827 | 15413.5 | 0.0 | 0.0 | A rapid method of total lipid extraction and purification. | E G Bligh, W J Dyer | Can J Biochem Physiol | 1959 | 13671378 | Yes |
| 30 | 29793 | 14896.5 | 0.0 | 0.0 | The measurement of observer agreement for categorical data. | J R Landis, G G Koch | Biometrics | 1977 | 843571 | Yes |
| 31 | 43649 | 14549.7 | 1258.85 | 419.6 | CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. | J D Thompson, D G Higgins, T J Gibson | Nucleic Acids Res | 1994 | 7984417 | Yes |
| 32 | 13811 | 13811.0 | 375.78 | 375.8 | MicroRNAs: target recognition and regulatory functions. | David P Bartel | Cell | 2009 | 19167326 | No |
| 33 | 13636 | 13636.0 | 402.15 | 402.1 | Projector augmented-wave method. | Blöchl | Phys Rev B Condens Matter | 1994 | 9976227 | Yes |
| 34 | 40829 | 13609.7 | 0.0 | 0.0 | A simple method for the isolation and purification of total lipides from animal tissues. | J Folch, M Lees, G H Sloane Stanley | J Biol Chem | 1957 | 13428781 | Yes |
| 35 | 13253 | 13253.0 | 558.98 | 559.0 | A power primer. | J Cohen | Psychol Bull | 1992 | 19565683 | Yes |
| 36 | 26253 | 13126.5 | 1008.49 | 504.2 | Meta-analysis in clinical trials. | R DerSimonian, N Laird | Control Clin Trials | 1986 | 3802833 | Yes |
| 37 | 25761 | 12880.5 | 1067.04 | 533.5 | The hospital anxiety and depression scale. | A S Zigmond, R P Snaith | Acta Psychiatr Scand | 1983 | 6880820 | Yes |
| 38 | 12637 | 12637.0 | 0.0 | 0.0 | Phosphorus assay in column chromatography. | G R Bartlett | J Biol Chem | 1959 | 13641241 | Yes |
| 39 | 12460 | 12460.0 | 633.12 | 633.1 | RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies. | Alexandros Stamatakis | Bioinformatics | 2014 | 24451623 | Yes |
| 40 | 12375 | 12375.0 | 490.87 | 490.9 | Catalase in vitro. | H Aebi | Methods Enzymol | 1984 | 6727660 | Yes |
| 41 | 35059 | 11686.3 | 1085.27 | 361.8 | Generalized Gradient Approximation Made Simple. | Perdew, Burke, Ernzerhof | Phys Rev Lett | 1996 | 10062328 | Yes |
| 42 | 56527 | 11305.4 | 1634.19 | 326.8 | Basic local alignment search tool. | S F Altschul, W Gish, W Miller, E W Myers, D J Lipman | J Mol Biol | 1990 | 2231712 | Yes |
| 43 | 22309 | 11154.5 | 941.62 | 470.8 | The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. | J E Ware, C D Sherbourne | Med Care | 1992 | 1593914 | Yes |
| 44 | 32928 | 10976.0 | 1201.98 | 400.7 | Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density. | Lee, Yang, Parr | Phys Rev B Condens Matter | 1988 | 9944570 | Yes |
| 45 | 21942 | 10971.0 | 604.29 | 302.1 | Fast and accurate short read alignment with Burrows-Wheeler transform. | Heng Li, Richard Durbin | Bioinformatics | 2009 | 19451168 | Yes |
| 46 | 21920 | 10960.0 | 479.37 | 239.7 | Coot: model-building tools for molecular graphics. | Paul Emsley, Kevin Cowtan | Acta Crystallogr D Biol Crystallogr | 2004 | 15572765 | Yes |
| 47 | 21571 | 10785.5 | 561.21 | 280.6 | A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. | A P Feinberg, B Vogelstein | Anal Biochem | 1983 | 6312838 | Yes |
| 48 | 10574 | 10574.0 | 356.18 | 356.2 | Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). | J F Kurtzke | Neurology | 1983 | 6685237 | Yes |
| 49 | 10340 | 10340.0 | 371.36 | 371.4 | Search and clustering orders of magnitude faster than BLAST. | Robert C Edgar | Bioinformatics | 2010 | 20709691 | Yes |
| 50 | 10330 | 10330.0 | 0.0 | 0.0 | Improvements in epoxy resin embedding methods. | J H Luft | J Biophys Biochem Cytol | 1961 | 13764136 | Yes |
| 51 | 20595 | 10297.5 | 742.21 | 371.1 | Fast gapped-read alignment with Bowtie 2. | Ben Langmead, Steven L Salzberg | Nat Methods | 2012 | 22388286 | Yes |
| 52 | 10277 | 10277.0 | 0.0 | 0.0 | The genetics of Caenorhabditis elegans. | S Brenner | Genetics | 1974 | 4366476 | Yes |
| 53 | 10188 | 10188.0 | 313.78 | 313.8 | The Psychophysics Toolbox. | D H Brainard | Spat Vis | 1997 | 9176952 | Yes |
| 54 | 20297 | 10148.5 | 454.84 | 227.4 | [20] Processing of X-ray diffraction data collected in oscillation mode. | Zbyszek Otwinowski, Wladek Minor | Methods Enzymol | 1997 | 27799103 | Yes |
| 55 | 10116 | 10116.0 | 387.02 | 387.0 | Structure validation in chemical crystallography. | Anthony L Spek | Acta Crystallogr D Biol Crystallogr | 2009 | 19171970 | Yes |
| 56 | 10023 | 10023.0 | 284.49 | 284.5 | Xds. | Wolfgang Kabsch | Acta Crystallogr D Biol Crystallogr | 2010 | 20124692 | Yes |
| 57 | 19828 | 9914.0 | 0.0 | 0.0 | The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. | K Weber, M Osborn | J Biol Chem | 1969 | 5806584 | Yes |
| 58 | 9822 | 9822.0 | 0.0 | 0.0 | Self-efficacy: toward a unifying theory of behavioral change. | A Bandura | Psychol Rev | 1977 | 847061 | Yes |
| 59 | 9474 | 9474.0 | 614.69 | 614.7 | Crystal structure refinement with SHELXL. | George M Sheldrick | Acta Crystallogr C Struct Chem | 2015 | 25567568 | Yes |
| 60 | 9438 | 9438.0 | 322.85 | 322.9 | Banting lecture 1988. Role of insulin resistance in human disease. | G M Reaven | Diabetes | 1988 | 3056758 | No |
| 61 | 9411 | 9411.0 | 368.92 | 368.9 | A new method for measuring daytime sleepiness: the Epworth sleepiness scale. | M W Johns | Sleep | 1991 | 1798888 | Yes |
| 62 | 9252 | 9252.0 | 269.63 | 269.6 | Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. | P S Thomas | Proc Natl Acad Sci U S A | 1980 | 6159641 | Yes |
| 63 | 18332 | 9166.0 | 516.45 | 258.2 | Quantifying heterogeneity in a meta-analysis. | Julian P T Higgins, Simon G Thompson | Stat Med | 2002 | 12111919 | Yes |
| 64 | 18260 | 9130.0 | 480.27 | 240.1 | A simple method for displaying the hydropathic character of a protein. | J Kyte, R F Doolittle | J Mol Biol | 1982 | 7108955 | Yes |
| 65 | 9127 | 9127.0 | 243.19 | 243.2 | Studies on transformation of Escherichia coli with plasmids. | D Hanahan | J Mol Biol | 1983 | 6345791 | Yes |
| 66 | 18249 | 9124.5 | 823.88 | 411.9 | The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. | R M Baron, D A Kenny | J Pers Soc Psychol | 1986 | 3806354 | Yes |
| 67 | 9069 | 9069.0 | 260.32 | 260.3 | The pathogenesis of atherosclerosis: a perspective for the 1990s. | R Ross | Nature | 1993 | 8479518 | No |
| 68 | 8970 | 8970.0 | 235.81 | 235.8 | Integrins: versatility, modulation, and signaling in cell adhesion. | R O Hynes | Cell | 1992 | 1555235 | No |
| 69 | 17760 | 8880.0 | 514.46 | 257.2 | Efficient iterative schemes for ab initio total-energy calculations using a plane-wave basis set. | Kresse, Furthmüller | Phys Rev B Condens Matter | 1996 | 9984901 | Yes |
| 70 | 8715 | 8715.0 | 190.59 | 190.6 | Mfold web server for nucleic acid folding and hybridization prediction. | Michael Zuker | Nucleic Acids Res | 2003 | 12824337 | Yes |
| 71 | 8673 | 8673.0 | 247.92 | 247.9 | Evolutionary trees from DNA sequences: a maximum likelihood approach. | J Felsenstein | J Mol Evol | 1981 | 7288891 | Yes |
| 72 | 8582 | 8582.0 | 0.0 | 0.0 | On the origin of cancer cells. | O Warburg | Science | 1956 | 13298683 | Yes |
| 73 | 8567 | 8567.0 | 234.76 | 234.8 | RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. | Alexandros Stamatakis | Bioinformatics | 2006 | 16928733 | Yes |
| 74 | 8448 | 8448.0 | 262.28 | 262.3 | Vitamin D deficiency. | Michael F Holick | N Engl J Med | 2007 | 17634462 | No |
| 75 | 25061 | 8353.7 | 668.17 | 222.7 | VMD: visual molecular dynamics. | W Humphrey, A Dalke, K Schulten | J Mol Graph | 1996 | 8744570 | Yes |
| 76 | 16590 | 8295.0 | 361.83 | 180.9 | The hallmarks of cancer. | D Hanahan, R A Weinberg | Cell | 2000 | 10647931 | No |
| 77 | 8251 | 8251.0 | 175.35 | 175.3 | Linear models and empirical bayes methods for assessing differential expression in microarray experiments. | Gordon K Smyth | Stat Appl Genet Mol Biol | 2004 | 16646809 | Yes |
| 78 | 32884 | 8221.0 | 985.63 | 246.4 | Measuring inconsistency in meta-analyses. | Julian P T Higgins, Simon G Thompson, Jonathan J Deeks, Douglas G Altman | BMJ | 2003 | 12958120 | No |
| 79 | 8118 | 8118.0 | 362.49 | 362.5 | Psychophysical bases of perceived exertion. | G A Borg | Med Sci Sports Exerc | 1982 | 7154893 | Yes |
| 80 | 7998 | 7998.0 | 0.0 | 0.0 | Solvent content of protein crystals. | B W Matthews | J Mol Biol | 1968 | 5700707 | Yes |
| 81 | 31811 | 7952.8 | 1351.22 | 337.8 | Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. | David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman | PLoS Med | 2009 | 19621072 | No |
| 82 | 7897 | 7897.0 | 174.27 | 174.3 | The functions of animal microRNAs. | Victor Ambros | Nature | 2004 | 15372042 | No |
| 83 | 7781 | 7781.0 | 218.86 | 218.9 | The role of protein kinase C in cell surface signal transduction and tumour promotion. | Y Nishizuka | Nature | 1984 | 6232463 | No |
| 84 | 7763 | 7763.0 | 218.63 | 218.6 | "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. | W N Burnette | Anal Biochem | 1981 | 6266278 | Yes |
| 85 | 23280 | 7760.0 | 1005.98 | 335.3 | Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. | Michael I Love, Wolfgang Huber, Simon Anders | Genome Biol | 2014 | 25516281 | Yes |
| 86 | 7730 | 7730.0 | 223.11 | 223.1 | Semiempirical GGA-type density functional constructed with a long-range dispersion correction. | Stefan Grimme | J Comput Chem | 2006 | 16955487 | Yes |
| 87 | 7708 | 7708.0 | 0.0 | 0.0 | A simplification of the protein assay method of Lowry et al. which is more generally applicable. | G L Peterson | Anal Biochem | 1977 | 603028 | Yes |
| 88 | 7667 | 7667.0 | 0.0 | 0.0 | Copper Enzymes In Isolated Chloroplasts. Polyphenoloxidase In Beta Vulgaris. | D I Arnon | Plant Physiol | 1949 | 16654194 | Yes |
| 89 | 7657 | 7657.0 | 207.05 | 207.1 | Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. | M C Hochberg | Arthritis Rheum | 1997 | 9324032 | Yes |
| 90 | 15195 | 7597.5 | 355.61 | 177.8 | Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. | Kazutoshi Takahashi, Shinya Yamanaka | Cell | 2006 | 16904174 | Yes |
| 91 | 30372 | 7593.0 | 1161.84 | 290.5 | A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. | M E Charlson, P Pompei, K L Ales, C R MacKenzie | J Chronic Dis | 1987 | 3558716 | Yes |
| 92 | 7585 | 7585.0 | 0.0 | 0.0 | Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. | J R Vane | Nat New Biol | 1971 | 5284360 | Yes |
| 93 | 22576 | 7525.3 | 630.13 | 210.0 | Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. | Da Wei Huang, Brad T Sherman, Richard A Lempicki | Nat Protoc | 2009 | 19131956 | Yes |
| 94 | 7375 | 7375.0 | 285.06 | 285.1 | Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. | Andreas Stang | Eur J Epidemiol | 2010 | 20652370 | Yes |
| 95 | 22037 | 7345.7 | 842.08 | 280.7 | NIH Image to ImageJ: 25 years of image analysis. | Caroline A Schneider, Wayne S Rasband, Kevin W Eliceiri | Nat Methods | 2012 | 22930834 | No |
| 96 | 7262 | 7262.0 | 0.0 | 0.0 | A low-viscosity epoxy resin embedding medium for electron microscopy. | A R Spurr | J Ultrastruct Res | 1969 | 4887011 | Yes |
| 97 | 7210 | 7210.0 | 240.99 | 241.0 | The blockade of immune checkpoints in cancer immunotherapy. | Drew M Pardoll | Nat Rev Cancer | 2012 | 22437870 | No |
| 98 | 7181 | 7181.0 | 0.0 | 0.0 | Tumor angiogenesis: therapeutic implications. | J Folkman | N Engl J Med | 1971 | 4938153 | No |
| 99 | 14335 | 7167.5 | 361.63 | 180.8 | MrBayes 3: Bayesian phylogenetic inference under mixed models. | Fredrik Ronquist, John P Huelsenbeck | Bioinformatics | 2003 | 12912839 | Yes |
| 100 | 28554 | 7138.5 | 949.21 | 237.3 | Bias in meta-analysis detected by a simple, graphical test. | M Egger, G Davey Smith, M Schneider, C Minder | BMJ | 1997 | 9310563 | Yes |
| 101 | 14186 | 7093.0 | 401.24 | 200.6 | Analyzing real-time PCR data by the comparative C(T) method. | Thomas D Schmittgen, Kenneth J Livak | Nat Protoc | 2008 | 18546601 | Yes |
| 102 | 7050 | 7050.0 | 213.57 | 213.6 | AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. | R W Cox | Comput Biomed Res | 1996 | 8812068 | Yes |
| 103 | 7021 | 7021.0 | 192.06 | 192.1 | Canonical dynamics: Equilibrium phase-space distributions. | Hoover | Phys Rev A Gen Phys | 1985 | 9895674 | Yes |
| 104 | 7011 | 7011.0 | 193.48 | 193.5 | TreeView: an application to display phylogenetic trees on personal computers. | R D Page | Comput Appl Biosci | 1996 | 8902363 | Yes |
| 105 | 6998 | 6998.0 | 0.0 | 0.0 | Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. | A Böyum | Scand J Clin Lab Invest Suppl | 1968 | 4179068 | Yes |
| 106 | 6969 | 6969.0 | 179.03 | 179.0 | PAML 4: phylogenetic analysis by maximum likelihood. | Ziheng Yang | Mol Biol Evol | 2007 | 17483113 | Yes |
| 107 | 20900 | 6966.7 | 0.0 | 0.0 | Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. | W T Friedewald, R I Levy, D S Fredrickson | Clin Chem | 1972 | 4337382 | Yes |
| 108 | 48740 | 6962.9 | 1282.53 | 183.2 | Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. | S F Altschul, T L Madden, A A Schäffer, J Zhang, Z Zhang, W Miller, D J Lipman | Nucleic Acids Res | 1997 | 9254694 | No |
| 109 | 6935 | 6935.0 | 236.55 | 236.6 | Density-functional approximation for the correlation energy of the inhomogeneous electron gas. | Perdew | Phys Rev B Condens Matter | 1986 | 9938299 | Yes |
| 110 | 13740 | 6870.0 | 614.5 | 307.2 | MAFFT multiple sequence alignment software version 7: improvements in performance and usability. | Kazutaka Katoh, Daron M Standley | Mol Biol Evol | 2013 | 23329690 | Yes |
| 111 | 6859 | 6859.0 | 156.59 | 156.6 | Chromatin modifications and their function. | Tony Kouzarides | Cell | 2007 | 17320507 | No |
| 112 | 6807 | 6807.0 | 183.79 | 183.8 | Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. | F Tajima | Genetics | 1989 | 2513255 | Yes |
| 113 | 6799 | 6799.0 | 322.35 | 322.4 | Comparative fit indexes in structural models. | P M Bentler | Psychol Bull | 1990 | 2320703 | Yes |
| 114 | 6775 | 6775.0 | 184.88 | 184.9 | The steroid and thyroid hormone receptor superfamily. | R M Evans | Science | 1988 | 3283939 | No |
| 115 | 20312 | 6770.7 | 947.65 | 315.9 | Trimmomatic: a flexible trimmer for Illumina sequence data. | Anthony M Bolger, Marc Lohse, Bjoern Usadel | Bioinformatics | 2014 | 24695404 | Yes |
| 116 | 13515 | 6757.5 | 0.0 | 0.0 | Continuous cultures of fused cells secreting antibody of predefined specificity. | G Köhler, C Milstein | Nature | 1975 | 1172191 | Yes |
| 117 | 13451 | 6725.5 | 288.55 | 144.3 | Processing of X-ray diffraction data collected in oscillation mode. | Z Otwinowski, W Minor | Methods Enzymol | 1997 | 27754618 | Yes |
| 118 | 13410 | 6705.0 | 297.21 | 148.6 | KEGG: kyoto encyclopedia of genes and genomes. | M Kanehisa, S Goto | Nucleic Acids Res | 2000 | 10592173 | Yes |
| 119 | 6703 | 6703.0 | 0.0 | 0.0 | The thiobarbituric acid assay of sialic acids. | L Warren | J Biol Chem | 1959 | 13672998 | Yes |
| 120 | 6682 | 6682.0 | 313.45 | 313.4 | Investigation of the freely available easy-to-use software 'EZR' for medical statistics. | Y Kanda | Bone Marrow Transplant | 2013 | 23208313 | Yes |
| 121 | 13334 | 6667.0 | 307.39 | 153.7 | Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana. | S J Clough, A F Bent | Plant J | 1998 | 10069079 | Yes |
| 122 | 19790 | 6596.7 | 565.08 | 188.4 | A new generation of Ca2+ indicators with greatly improved fluorescence properties. | G Grynkiewicz, M Poenie, R Y Tsien | J Biol Chem | 1985 | 3838314 | Yes |
| 123 | 6582 | 6582.0 | 169.43 | 169.4 | Fast robust automated brain extraction. | Stephen M Smith | Hum Brain Mapp | 2002 | 12391568 | No |
| 124 | 6580 | 6580.0 | 0.0 | 0.0 | The assessment of anxiety states by rating. | M Hamilton | Br J Med Psychol | 1959 | 13638508 | Yes |
| 125 | 6521 | 6521.0 | 183.18 | 183.2 | Apoptosis: a review of programmed cell death. | Susan Elmore | Toxicol Pathol | 2007 | 17562483 | No |
| 126 | 6508 | 6508.0 | 172.64 | 172.6 | Adhesion receptors of the immune system. | T A Springer | Nature | 1990 | 1974032 | No |
| 127 | 6412 | 6412.0 | 197.79 | 197.8 | The VideoToolbox software for visual psychophysics: transforming numbers into movies. | D G Pelli | Spat Vis | 1997 | 9176953 | Yes |
| 128 | 6406 | 6406.0 | 169.4 | 169.4 | Angiogenesis in cancer, vascular, rheumatoid and other disease. | J Folkman | Nat Med | 1995 | 7584949 | No |
| 129 | 12761 | 6380.5 | 0.0 | 0.0 | Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. | Y Cheng, W H Prusoff | Biochem Pharmacol | 1973 | 4202581 | Yes |
| 130 | 6362 | 6362.0 | 130.41 | 130.4 | Rapid and efficient site-specific mutagenesis without phenotypic selection. | T A Kunkel | Proc Natl Acad Sci U S A | 1985 | 3881765 | Yes |
| 131 | 12648 | 6324.0 | 0.0 | 0.0 | Statistical aspects of the analysis of data from retrospective studies of disease. | N Mantel, W Haenszel | J Natl Cancer Inst | 1959 | 13655060 | Yes |
| 132 | 6255 | 6255.0 | 208.09 | 208.1 | Ethical guidelines for investigations of experimental pain in conscious animals. | Manfred Zimmermann | Pain | 1983 | 6877845 | No |
| 133 | 18747 | 6249.0 | 1374.24 | 458.1 | MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets. | Sudhir Kumar, Glen Stecher, Koichiro Tamura | Mol Biol Evol | 2016 | 27004904 | Yes |
| 134 | 6186 | 6186.0 | 135.37 | 135.4 | p53, the cellular gatekeeper for growth and division. | A J Levine | Cell | 1997 | 9039259 | No |
| 135 | 6120 | 6120.0 | 201.04 | 201.0 | The Clinical Dementia Rating (CDR): current version and scoring rules. | J C Morris | Neurology | 1993 | 8232972 | Yes |
| 136 | 12213 | 6106.5 | 0.0 | 0.0 | A rapid alkaline extraction procedure for screening recombinant plasmid DNA. | H C Birnboim, J Doly | Nucleic Acids Res | 1979 | 388356 | Yes |
| 137 | 6031 | 6031.0 | 150.17 | 150.2 | Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. | T A Springer | Cell | 1994 | 7507411 | No |
| 138 | 12016 | 6008.0 | 0.0 | 0.0 | Prediction of creatinine clearance from serum creatinine. | D W Cockcroft, M H Gault | Nephron | 1976 | 1244564 | Yes |
| 139 | 24011 | 6002.8 | 0.0 | 0.0 | Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. | J M Chirgwin, A E Przybyla, R J MacDonald, W J Rutter | Biochemistry | 1979 | 518835 | Yes |
| 140 | 5982 | 5982.0 | 123.78 | 123.8 | Integrins: bidirectional, allosteric signaling machines. | Richard O Hynes | Cell | 2002 | 12297042 | No |
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| 3511 | 1008 | 1008.0 | 18.72 | 18.7 | Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. | R A Frye | Biochem Biophys Res Commun | 2000 | 10873683 | Yes |
| 3512 | 1008 | 1008.0 | 19.15 | 19.1 | NFAT proteins: key regulators of T-cell development and function. | Fernando Macian | Nat Rev Immunol | 2005 | 15928679 | No |
| 3513 | 2016 | 1008.0 | 46.31 | 23.2 | Regulation of translation initiation in eukaryotes: mechanisms and biological targets. | Nahum Sonenberg, Alan G Hinnebusch | Cell | 2009 | 19239892 | No |
| 3514 | 2015 | 1007.5 | 52.73 | 26.4 | Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. | M Tsujii, R N DuBois | Cell | 1995 | 8521479 | Yes |
| 3515 | 1007 | 1007.0 | 31.66 | 31.7 | Topography of cognition: parallel distributed networks in primate association cortex. | P S Goldman-Rakic | Annu Rev Neurosci | 1988 | 3284439 | No |
| 3516 | 1007 | 1007.0 | 41.25 | 41.2 | Absorption, transport, and hepatic metabolism of copper and zinc: special reference to metallothionein and ceruloplasmin. | R J Cousins | Physiol Rev | 1985 | 3885271 | No |
| 3517 | 2014 | 1007.0 | 0.0 | 0.0 | The period of susceptibility to the physiological effects of unilateral eye closure in kittens. | D H Hubel, T N Wiesel | J Physiol | 1970 | 5498493 | Yes |
| 3518 | 1007 | 1007.0 | 0.0 | 0.0 | The Stability of Broken Ends of Chromosomes in Zea Mays. | B McClintock | Genetics | 1941 | 17247004 | Yes |
| 3519 | 10066 | 1006.6 | 242.22 | 24.2 | Scalable molecular dynamics with NAMD. | James C Phillips, Rosemary Braun, Wei Wang, James Gumbart, Emad Tajkhorshid, Elizabeth Villa, Christophe Chipot, Robert D Skeel, Laxmikant Kalé, Klaus Schulten | J Comput Chem | 2005 | 16222654 | Yes |
| 3520 | 9057 | 1006.3 | 258.73 | 28.7 | MolProbity: all-atom structure validation for macromolecular crystallography. | Vincent B Chen, W Bryan Arendall, Jeffrey J Headd, Daniel A Keedy, Robert M Immormino, Gary J Kapral, Laura W Murray, Jane S Richardson, David C Richardson | Acta Crystallogr D Biol Crystallogr | 2010 | 20057044 | Yes |
| 3521 | 2012 | 1006.0 | 0.0 | 0.0 | Comparative aspects of the brain growth spurt. | J Dobbing, J Sands | Early Hum Dev | 1979 | 118862 | Yes |
| 3522 | 1006 | 1006.0 | 28.98 | 29.0 | Advanced protein glycosylation in diabetes and aging. | M Brownlee | Annu Rev Med | 1995 | 7598459 | No |
| 3523 | 1006 | 1006.0 | 38.1 | 38.1 | Cellular mechanisms of muscle fatigue. | R H Fitts | Physiol Rev | 1994 | 8295935 | No |
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