Unicorn Papers - Top cited papers from PUBMED

No.	Citations	EC_cit	RCR	EC_RCR	Title	Authors	Journal	Year	PMID	Article(?)
1	221515	221515.0	0.0	0.0	Cleavage of structural proteins during the assembly of the head of bacteriophage T4.	U K Laemmli	Nature	1970	5432063	Yes
2	168491	168491.0	0.0	0.0	A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.	M M Bradford	Anal Biochem	1976	942051	Yes
3	285734	71433.5	0.0	0.0	Protein measurement with the Folin phenol reagent.	O H Lowry, N J Rosebrough, A L Farr, R J Randall	J Biol Chem	1951	14907713	Yes
4	97139	48569.5	2502.32	1251.2	Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.	K J Livak, T D Schmittgen	Methods	2001	11846609	Yes
5	42965	42965.0	1452.94	1452.9	A short history of SHELX.	George M Sheldrick	Acta Crystallogr A	2008	18156677	Yes
6	33598	33598.0	1091.08	1091.1	Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.	T Mosmann	J Immunol Methods	1983	6606682	Yes
7	65082	32541.0	1973.67	986.8	Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.	P Chomczynski, N Sacchi	Anal Biochem	1987	2440339	Yes
8	30167	30167.0	0.0	0.0	Detection of specific sequences among DNA fragments separated by gel electrophoresis.	E M Southern	J Mol Biol	1975	1195397	Yes
9	25336	25336.0	0.0	0.0	The assessment and analysis of handedness: the Edinburgh inventory.	R C Oldfield	Neuropsychologia	1971	5146491	Yes
10	24982	24982.0	578.06	578.1	MicroRNAs: genomics, biogenesis, mechanism, and function.	David P Bartel	Cell	2004	14744438	No
11	23577	23577.0	0.0	0.0	A rating scale for depression.	M Hamilton	J Neurol Neurosurg Psychiatry	1960	14399272	Yes
12	22332	22332.0	701.74	701.7	Confidence Limits On Phylogenies: An Approach Using The Bootstrap.	Joseph Felsenstein	Evolution	1985	28561359	Yes
13	65336	21778.7	0.0	0.0	DNA sequencing with chain-terminating inhibitors.	F Sanger, S Nicklen, A R Coulson	Proc Natl Acad Sci U S A	1977	271968	Yes
14	21552	21552.0	536.01	536.0	MUSCLE: multiple sequence alignment with high accuracy and high throughput.	Robert C Edgar	Nucleic Acids Res	2004	15034147	Yes
15	21406	21406.0	510.24	510.2	A new mathematical model for relative quantification in real-time RT-PCR.	M W Pfaffl	Nucleic Acids Res	2001	11328886	Yes
16	60151	20050.3	0.0	0.0	"Mini-mental state". A practical method for grading the cognitive state of patients for the clinician.	M F Folstein, S E Folstein, P R McHugh	J Psychiatr Res	1975	1202204	Yes
17	19937	19937.0	0.0	0.0	The use of lead citrate at high pH as an electron-opaque stain in electron microscopy.	E S Reynolds	J Cell Biol	1963	13986422	Yes
18	36730	18365.0	1139.67	569.8	The neighbor-joining method: a new method for reconstructing phylogenetic trees.	N Saitou, M Nei	Mol Biol Evol	1987	3447015	Yes
19	18183	18183.0	646.67	646.7	Density-functional exchange-energy approximation with correct asymptotic behavior.	Becke	Phys Rev A Gen Phys	1988	9900728	Yes
20	18091	18091.0	0.0	0.0	Tissue sulfhydryl groups.	G L Ellman	Arch Biochem Biophys	1959	13650640	Yes
21	53130	17710.0	0.0	0.0	Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.	H Towbin, T Staehelin, J Gordon	Proc Natl Acad Sci U S A	1979	388439	Yes
22	16797	16797.0	0.0	0.0	Disc Electrophoresis. Ii. Method And Application To Human Serum Proteins.	B J Davis	Ann N Y Acad Sci	1964	14240539	Yes
23	33399	16699.5	1616.41	808.2	Statistical methods for assessing agreement between two methods of clinical measurement.	J M Bland, D G Altman	Lancet	1986	2868172	Yes
24	32810	16405.0	1162.18	581.1	Hallmarks of cancer: the next generation.	Douglas Hanahan, Robert A Weinberg	Cell	2011	21376230	No
25	16399	16399.0	0.0	0.0	High resolution two-dimensional electrophoresis of proteins.	P H O'Farrell	J Biol Chem	1975	236308	Yes
26	16088	16088.0	419.45	419.4	Atherosclerosis--an inflammatory disease.	R Ross	N Engl J Med	1999	9887164	No
27	15898	15898.0	0.0	0.0	A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid.	K Burton	Biochem J	1956	13293190	Yes
28	15350	15350.0	573.89	573.9	A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences.	M Kimura	J Mol Evol	1980	7463489	Yes
29	30632	15316.0	0.0	0.0	A rapid method of total lipid extraction and purification.	E G Bligh, W J Dyer	Can J Biochem Physiol	1959	13671378	Yes
30	29276	14638.0	0.0	0.0	The measurement of observer agreement for categorical data.	J R Landis, G G Koch	Biometrics	1977	843571	Yes
31	43353	14451.0	1254.22	418.1	CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.	J D Thompson, D G Higgins, T J Gibson	Nucleic Acids Res	1994	7984417	Yes
32	41071	13690.3	0.0	0.0	A simple method for the isolation and purification of total lipides from animal tissues.	J Folch, M Lees, G H Sloane Stanley	J Biol Chem	1957	13428781	Yes
33	13450	13450.0	370.89	370.9	MicroRNAs: target recognition and regulatory functions.	David P Bartel	Cell	2009	19167326	No
34	12983	12983.0	385.15	385.1	Projector augmented-wave method.	Blöchl	Phys Rev B Condens Matter	1994	9976227	Yes
35	12931	12931.0	547.84	547.8	A power primer.	J Cohen	Psychol Bull	1992	19565683	Yes
36	25588	12794.0	984.53	492.3	Meta-analysis in clinical trials.	R DerSimonian, N Laird	Control Clin Trials	1986	3802833	Yes
37	12705	12705.0	0.0	0.0	Phosphorus assay in column chromatography.	G R Bartlett	J Biol Chem	1959	13641241	Yes
38	25029	12514.5	1040.28	520.1	The hospital anxiety and depression scale.	A S Zigmond, R P Snaith	Acta Psychiatr Scand	1983	6880820	Yes
39	12050	12050.0	479.07	479.1	Catalase in vitro.	H Aebi	Methods Enzymol	1984	6727660	Yes
40	11666	11666.0	613.8	613.8	RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies.	Alexandros Stamatakis	Bioinformatics	2014	24451623	Yes
41	33553	11184.3	1043.09	347.7	Generalized Gradient Approximation Made Simple.	Perdew, Burke, Ernzerhof	Phys Rev Lett	1996	10062328	Yes
42	55441	11088.2	1603.48	320.7	Basic local alignment search tool.	S F Altschul, W Gish, W Miller, E W Myers, D J Lipman	J Mol Biol	1990	2231712	Yes
43	22078	11039.0	936.44	468.2	The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection.	J E Ware, C D Sherbourne	Med Care	1992	1593914	Yes
44	21560	10780.0	562.4	281.2	A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.	A P Feinberg, B Vogelstein	Anal Biochem	1983	6312838	Yes
45	21511	10755.5	474.97	237.5	Coot: model-building tools for molecular graphics.	Paul Emsley, Kevin Cowtan	Acta Crystallogr D Biol Crystallogr	2004	15572765	Yes
46	32154	10718.0	1177.34	392.4	Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density.	Lee, Yang, Parr	Phys Rev B Condens Matter	1988	9944570	Yes
47	20827	10413.5	580.45	290.2	Fast and accurate short read alignment with Burrows-Wheeler transform.	Heng Li, Richard Durbin	Bioinformatics	2009	19451168	Yes
48	10387	10387.0	351.18	351.2	Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS).	J F Kurtzke	Neurology	1983	6685237	Yes
49	10314	10314.0	0.0	0.0	Improvements in epoxy resin embedding methods.	J H Luft	J Biophys Biochem Cytol	1961	13764136	Yes
50	10063	10063.0	393.79	393.8	Structure validation in chemical crystallography.	Anthony L Spek	Acta Crystallogr D Biol Crystallogr	2009	19171970	Yes
51	10060	10060.0	0.0	0.0	The genetics of Caenorhabditis elegans.	S Brenner	Genetics	1974	4366476	Yes
52	19963	9981.5	0.0	0.0	The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis.	K Weber, M Osborn	J Biol Chem	1969	5806584	Yes
53	19917	9958.5	449.16	224.6	[20] Processing of X-ray diffraction data collected in oscillation mode.	Zbyszek Otwinowski, Wladek Minor	Methods Enzymol	1997	27799103	Yes
54	9957	9957.0	308.32	308.3	The Psychophysics Toolbox.	D H Brainard	Spat Vis	1997	9176952	Yes
55	9906	9906.0	363.62	363.6	Search and clustering orders of magnitude faster than BLAST.	Robert C Edgar	Bioinformatics	2010	20709691	Yes
56	9696	9696.0	280.22	280.2	Xds.	Wolfgang Kabsch	Acta Crystallogr D Biol Crystallogr	2010	20124692	Yes
57	9636	9636.0	0.0	0.0	Self-efficacy: toward a unifying theory of behavioral change.	A Bandura	Psychol Rev	1977	847061	Yes
58	19220	9610.0	708.06	354.0	Fast gapped-read alignment with Bowtie 2.	Ben Langmead, Steven L Salzberg	Nat Methods	2012	22388286	Yes
59	9464	9464.0	324.97	325.0	Banting lecture 1988. Role of insulin resistance in human disease.	G M Reaven	Diabetes	1988	3056758	No
60	9248	9248.0	269.92	269.9	Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.	P S Thomas	Proc Natl Acad Sci U S A	1980	6159641	Yes
61	9182	9182.0	361.39	361.4	A new method for measuring daytime sleepiness: the Epworth sleepiness scale.	M W Johns	Sleep	1991	1798888	Yes
62	9085	9085.0	242.75	242.8	Studies on transformation of Escherichia coli with plasmids.	D Hanahan	J Mol Biol	1983	6345791	Yes
63	18140	9070.0	476.95	238.5	A simple method for displaying the hydropathic character of a protein.	J Kyte, R F Doolittle	J Mol Biol	1982	7108955	Yes
64	9044	9044.0	260.16	260.2	The pathogenesis of atherosclerosis: a perspective for the 1990s.	R Ross	Nature	1993	8479518	No
65	18008	9004.0	816.7	408.4	The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations.	R M Baron, D A Kenny	J Pers Soc Psychol	1986	3806354	Yes
66	8939	8939.0	235.97	236.0	Integrins: versatility, modulation, and signaling in cell adhesion.	R O Hynes	Cell	1992	1555235	No
67	8897	8897.0	605.74	605.7	Crystal structure refinement with SHELXL.	George M Sheldrick	Acta Crystallogr C Struct Chem	2015	25567568	Yes
68	17561	8780.5	498.18	249.1	Quantifying heterogeneity in a meta-analysis.	Julian P T Higgins, Simon G Thompson	Stat Med	2002	12111919	Yes
69	8568	8568.0	188.53	188.5	Mfold web server for nucleic acid folding and hybridization prediction.	Michael Zuker	Nucleic Acids Res	2003	12824337	Yes
70	8482	8482.0	242.0	242.0	Evolutionary trees from DNA sequences: a maximum likelihood approach.	J Felsenstein	J Mol Evol	1981	7288891	Yes
71	16857	8428.5	490.74	245.4	Efficient iterative schemes for ab initio total-energy calculations using a plane-wave basis set.	Kresse, Furthmüller	Phys Rev B Condens Matter	1996	9984901	Yes
72	8413	8413.0	233.34	233.3	RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models.	Alexandros Stamatakis	Bioinformatics	2006	16928733	Yes
73	8338	8338.0	0.0	0.0	On the origin of cancer cells.	O Warburg	Science	1956	13298683	Yes
74	8292	8292.0	261.46	261.5	Vitamin D deficiency.	Michael F Holick	N Engl J Med	2007	17634462	No
75	8160	8160.0	174.8	174.8	Linear models and empirical bayes methods for assessing differential expression in microarray experiments.	Gordon K Smyth	Stat Appl Genet Mol Biol	2004	16646809	Yes
76	16315	8157.5	357.26	178.6	The hallmarks of cancer.	D Hanahan, R A Weinberg	Cell	2000	10647931	No
77	24081	8027.0	643.8	214.6	VMD: visual molecular dynamics.	W Humphrey, A Dalke, K Schulten	J Mol Graph	1996	8744570	Yes
78	7984	7984.0	0.0	0.0	Solvent content of protein crystals.	B W Matthews	J Mol Biol	1968	5700707	Yes
79	7969	7969.0	357.57	357.6	Psychophysical bases of perceived exertion.	G A Borg	Med Sci Sports Exerc	1982	7154893	Yes
80	31517	7879.2	952.36	238.1	Measuring inconsistency in meta-analyses.	Julian P T Higgins, Simon G Thompson, Jonathan J Deeks, Douglas G Altman	BMJ	2003	12958120	No
81	7768	7768.0	218.63	218.6	The role of protein kinase C in cell surface signal transduction and tumour promotion.	Y Nishizuka	Nature	1984	6232463	No
82	7750	7750.0	172.29	172.3	The functions of animal microRNAs.	Victor Ambros	Nature	2004	15372042	No
83	7746	7746.0	218.38	218.4	"Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A.	W N Burnette	Anal Biochem	1981	6266278	Yes
84	7689	7689.0	0.0	0.0	A simplification of the protein assay method of Lowry et al. which is more generally applicable.	G L Peterson	Anal Biochem	1977	603028	Yes
85	7567	7567.0	0.0	0.0	Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.	J R Vane	Nat New Biol	1971	5284360	Yes
86	7524	7524.0	0.0	0.0	Copper Enzymes In Isolated Chloroplasts. Polyphenoloxidase In Beta Vulgaris.	D I Arnon	Plant Physiol	1949	16654194	Yes
87	7470	7470.0	218.71	218.7	Semiempirical GGA-type density functional constructed with a long-range dispersion correction.	Stefan Grimme	J Comput Chem	2006	16955487	Yes
88	7468	7468.0	203.35	203.3	Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus.	M C Hochberg	Arthritis Rheum	1997	9324032	Yes
89	14858	7429.0	351.54	175.8	Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.	Kazutoshi Takahashi, Shinya Yamanaka	Cell	2006	16904174	Yes
90	29325	7331.2	1123.25	280.8	A new method of classifying prognostic comorbidity in longitudinal studies: development and validation.	M E Charlson, P Pompei, K L Ales, C R MacKenzie	J Chronic Dis	1987	3558716	Yes
91	21975	7325.0	619.76	206.6	Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources.	Da Wei Huang, Brad T Sherman, Richard A Lempicki	Nat Protoc	2009	19131956	Yes
92	29268	7317.0	1264.5	316.1	Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.	David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman	PLoS Med	2009	19621072	No
93	7239	7239.0	0.0	0.0	A low-viscosity epoxy resin embedding medium for electron microscopy.	A R Spurr	J Ultrastruct Res	1969	4887011	Yes
94	7090	7090.0	0.0	0.0	Tumor angiogenesis: therapeutic implications.	J Folkman	N Engl J Med	1971	4938153	No
95	14141	7070.5	359.2	179.6	MrBayes 3: Bayesian phylogenetic inference under mixed models.	Fredrik Ronquist, John P Huelsenbeck	Bioinformatics	2003	12912839	Yes
96	6998	6998.0	0.0	0.0	Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.	A Böyum	Scand J Clin Lab Invest Suppl	1968	4179068	Yes
97	6996	6996.0	193.87	193.9	TreeView: an application to display phylogenetic trees on personal computers.	R D Page	Comput Appl Biosci	1996	8902363	Yes
98	20808	6936.0	814.99	271.7	NIH Image to ImageJ: 25 years of image analysis.	Caroline A Schneider, Wayne S Rasband, Kevin W Eliceiri	Nat Methods	2012	22930834	No
99	20740	6913.3	919.13	306.4	Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2.	Michael I Love, Wolfgang Huber, Simon Anders	Genome Biol	2014	25516281	Yes
100	20738	6912.7	0.0	0.0	Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.	W T Friedewald, R I Levy, D S Fredrickson	Clin Chem	1972	4337382	Yes
101	48256	6893.7	1275.31	182.2	Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.	S F Altschul, T L Madden, A A Schäffer, J Zhang, Z Zhang, W Miller, D J Lipman	Nucleic Acids Res	1997	9254694	No
102	6881	6881.0	209.37	209.4	AFNI: software for analysis and visualization of functional magnetic resonance neuroimages.	R W Cox	Comput Biomed Res	1996	8812068	Yes
103	27500	6875.0	917.35	229.3	Bias in meta-analysis detected by a simple, graphical test.	M Egger, G Davey Smith, M Schneider, C Minder	BMJ	1997	9310563	Yes
104	6849	6849.0	234.3	234.3	The blockade of immune checkpoints in cancer immunotherapy.	Drew M Pardoll	Nat Rev Cancer	2012	22437870	No
105	6846	6846.0	270.25	270.2	Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses.	Andreas Stang	Eur J Epidemiol	2010	20652370	Yes
106	13644	6822.0	390.81	195.4	Analyzing real-time PCR data by the comparative C(T) method.	Thomas D Schmittgen, Kenneth J Livak	Nat Protoc	2008	18546601	Yes
107	6797	6797.0	186.59	186.6	Canonical dynamics: Equilibrium phase-space distributions.	Hoover	Phys Rev A Gen Phys	1985	9895674	Yes
108	6796	6796.0	232.45	232.4	Density-functional approximation for the correlation energy of the inhomogeneous electron gas.	Perdew	Phys Rev B Condens Matter	1986	9938299	Yes
109	6775	6775.0	0.0	0.0	The thiobarbituric acid assay of sialic acids.	L Warren	J Biol Chem	1959	13672998	Yes
110	6746	6746.0	184.09	184.1	The steroid and thyroid hormone receptor superfamily.	R M Evans	Science	1988	3283939	No
111	13458	6729.0	0.0	0.0	Continuous cultures of fused cells secreting antibody of predefined specificity.	G Köhler, C Milstein	Nature	1975	1172191	Yes
112	6721	6721.0	175.12	175.1	PAML 4: phylogenetic analysis by maximum likelihood.	Ziheng Yang	Mol Biol Evol	2007	17483113	Yes
113	6713	6713.0	155.32	155.3	Chromatin modifications and their function.	Tony Kouzarides	Cell	2007	17320507	No
114	13344	6672.0	287.66	143.8	Processing of X-ray diffraction data collected in oscillation mode.	Z Otwinowski, W Minor	Methods Enzymol	1997	27754618	Yes
115	6663	6663.0	179.95	179.9	Statistical method for testing the neutral mutation hypothesis by DNA polymorphism.	F Tajima	Genetics	1989	2513255	Yes
116	19861	6620.3	567.25	189.1	A new generation of Ca2+ indicators with greatly improved fluorescence properties.	G Grynkiewicz, M Poenie, R Y Tsien	J Biol Chem	1985	3838314	Yes
117	6610	6610.0	315.45	315.4	Comparative fit indexes in structural models.	P M Bentler	Psychol Bull	1990	2320703	Yes
118	13018	6509.0	301.19	150.6	Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana.	S J Clough, A F Bent	Plant J	1998	10069079	Yes
119	6494	6494.0	172.69	172.7	Adhesion receptors of the immune system.	T A Springer	Nature	1990	1974032	No
120	6447	6447.0	0.0	0.0	The assessment of anxiety states by rating.	M Hamilton	Br J Med Psychol	1959	13638508	Yes
121	6416	6416.0	166.69	166.7	Fast robust automated brain extraction.	Stephen M Smith	Hum Brain Mapp	2002	12391568	No
122	12799	6399.5	284.32	142.2	KEGG: kyoto encyclopedia of genes and genomes.	M Kanehisa, S Goto	Nucleic Acids Res	2000	10592173	Yes
123	6383	6383.0	169.59	169.6	Angiogenesis in cancer, vascular, rheumatoid and other disease.	J Folkman	Nat Med	1995	7584949	No
124	6354	6354.0	130.14	130.1	Rapid and efficient site-specific mutagenesis without phenotypic selection.	T A Kunkel	Proc Natl Acad Sci U S A	1985	3881765	Yes
125	12690	6345.0	582.9	291.4	MAFFT multiple sequence alignment software version 7: improvements in performance and usability.	Kazutaka Katoh, Daron M Standley	Mol Biol Evol	2013	23329690	Yes
126	12685	6342.5	0.0	0.0	Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction.	Y Cheng, W H Prusoff	Biochem Pharmacol	1973	4202581	Yes
127	6303	6303.0	178.88	178.9	Apoptosis: a review of programmed cell death.	Susan Elmore	Toxicol Pathol	2007	17562483	No
128	6293	6293.0	195.21	195.2	The VideoToolbox software for visual psychophysics: transforming numbers into movies.	D G Pelli	Spat Vis	1997	9176953	Yes
129	12545	6272.5	0.0	0.0	Statistical aspects of the analysis of data from retrospective studies of disease.	N Mantel, W Haenszel	J Natl Cancer Inst	1959	13655060	Yes
130	6189	6189.0	206.7	206.7	Ethical guidelines for investigations of experimental pain in conscious animals.	Manfred Zimmermann	Pain	1983	6877845	No
131	18547	6182.3	894.28	298.1	Trimmomatic: a flexible trimmer for Illumina sequence data.	Anthony M Bolger, Marc Lohse, Bjoern Usadel	Bioinformatics	2014	24695404	Yes
132	6156	6156.0	135.64	135.6	p53, the cellular gatekeeper for growth and division.	A J Levine	Cell	1997	9039259	No
133	12189	6094.5	0.0	0.0	A rapid alkaline extraction procedure for screening recombinant plasmid DNA.	H C Birnboim, J Doly	Nucleic Acids Res	1979	388356	Yes
134	6064	6064.0	292.0	292.0	Investigation of the freely available easy-to-use software 'EZR' for medical statistics.	Y Kanda	Bone Marrow Transplant	2013	23208313	Yes
135	6023	6023.0	150.53	150.5	Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm.	T A Springer	Cell	1994	7507411	No
136	23989	5997.2	0.0	0.0	Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.	J M Chirgwin, A E Przybyla, R J MacDonald, W J Rutter	Biochemistry	1979	518835	Yes
137	17894	5964.7	1370.43	456.8	MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets.	Sudhir Kumar, Glen Stecher, Koichiro Tamura	Mol Biol Evol	2016	27004904	Yes
138	5951	5951.0	152.68	152.7	Inositol trisphosphate and calcium signalling.	M J Berridge	Nature	1993	8381210	No
139	11895	5947.5	0.0	0.0	Prediction of creatinine clearance from serum creatinine.	D W Cockcroft, M H Gault	Nephron	1976	1244564	Yes
140	5933	5933.0	195.23	195.2	The Clinical Dementia Rating (CDR): current version and scoring rules.	J C Morris	Neurology	1993	8232972	Yes
141	5919	5919.0	152.48	152.5	G proteins: transducers of receptor-generated signals.	A G Gilman	Annu Rev Biochem	1987	3113327	No
142	5881	5881.0	122.48	122.5	Integrins: bidirectional, allosteric signaling machines.	Richard O Hynes	Cell	2002	12297042	No
143	5822	5822.0	133.82	133.8	Inflammation in atherosclerosis.	Peter Libby	Nature	2002	12490960	No
144	11565	5782.5	0.0	0.0	Intraclass correlations: uses in assessing rater reliability.	P E Shrout, J L Fleiss	Psychol Bull	1979	18839484	No
145	5743	5743.0	144.6	144.6	Inflammation, atherosclerosis, and coronary artery disease.	Göran K Hansson	N Engl J Med	2005	15843671	No
146	11432	5716.0	0.0	0.0	The Carbon Monoxide-Binding Pigment Of Liver Microsomes. I. Evidence For Its Hemoprotein Nature.	T Omura, R Sato	J Biol Chem	1964	14209971	Yes
147	11330	5665.0	403.21	201.6	The meaning and use of the area under a receiver operating characteristic (ROC) curve.	J A Hanley, B J McNeil	Radiology	1982	7063747	Yes
148	5643	5643.0	144.65	144.7	Apoptosis in the pathogenesis and treatment of disease.	C B Thompson	Science	1995	7878464	No
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3473	995	995.0	27.29	27.3	The molecular biology and functions of the granulocyte-macrophage colony-stimulating factors.	D Metcalf	Blood	1986	3002522	No
3474	1990	995.0	44.88	22.4	Caspases: killer proteases.	D W Nicholson, N A Thornberry	Trends Biochem Sci	1997	9270303	No
3475	995	995.0	23.19	23.2	Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes.	J Denis McGarry	Diabetes	2002	11756317	No
3476	995	995.0	32.35	32.4	Sensorimotor integration in human postural control.	R J Peterka	J Neurophysiol	2002	12205132	Yes
3477	2983	994.3	103.05	34.4	The 'Trier Social Stress Test'--a tool for investigating psychobiological stress responses in a laboratory setting.	C Kirschbaum, K M Pirke, D H Hellhammer	Neuropsychobiology	1993	8255414	Yes
3478	3977	994.2	94.69	23.7	The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis.	R M Kluck, E Bossy-Wetzel, D R Green, D D Newmeyer	Science	1997	9027315	Yes
3479	994	994.0	56.84	56.8	Calcium phosphate ceramics as hard tissue prosthetics.	M Jarcho	Clin Orthop Relat Res	1981	7018783	No
3480	2982	994.0	87.9	29.3	A sensitive and reliable locomotor rating scale for open field testing in rats.	D M Basso, M S Beattie, J C Bresnahan	J Neurotrauma	1995	7783230	Yes
3481	994	994.0	25.89	25.9	Skeletal complications of malignancy.	R E Coleman	Cancer	1997	9362426	No
3482	994	994.0	0.0	0.0	Pelvic Scoring For Elective Induction.	E H Bishop	Obstet Gynecol	1964	14199536	Yes
3483	994	994.0	32.91	32.9	Isolation By Distance In Equilibrium And Non-Equilibrium Populations.	Montgomery Slatkin	Evolution	1993	28568097	Yes
3484	2981	993.7	130.61	43.5	Measurement of health status. Ascertaining the minimal clinically important difference.	R Jaeschke, J Singer, G H Guyatt	Control Clin Trials	1989	2691207	Yes
3485	4968	993.6	153.12	30.6	The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells.	R Moll, W W Franke, D L Schiller, B Geiger, R Krepler	Cell	1982	6186379	No

_{Unicorn Papers}

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Volume 16, December 2021