Unicorn Papers - Top cited papers from PUBMED

No.	Citations	EC_cit	RCR	EC_RCR	Title	Authors	Journal	Year	PMID	Article(?)
1	226830	226830.0	6242.4	6242.4	Cleavage of structural proteins during the assembly of the head of bacteriophage T4.	U K Laemmli	Nature	1970	5432063	Yes
2	184714	184714.0	6057.8	6057.8	A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.	M M Bradford	Anal Biochem	1976	942051	Yes
3	145734	72867.0	4012.2	2006.1	Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.	K J Livak, T D Schmittgen	Methods	2001	11846609	Yes
4	288991	72247.8	0.0	0.0	Protein measurement with the Folin phenol reagent.	O H Lowry, N J Rosebrough, A L Farr, R J Randall	J Biol Chem	1951	14907713	Yes
5	47216	47216.0	1512.1	1512.1	A short history of SHELX.	George M Sheldrick	Acta Crystallogr A	2008	18156677	Yes
6	39715	39715.0	1322.9	1322.9	Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.	T Mosmann	J Immunol Methods	1983	6606682	Yes
7	64918	32459.0	2017.5	1008.8	Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.	P Chomczynski, N Sacchi	Anal Biochem	1987	2440339	Yes
8	31054	31054.0	789.0	789.0	MUSCLE: multiple sequence alignment with high accuracy and high throughput.	Robert C Edgar	Nucleic Acids Res	2004	15034147	Yes
9	30283	30283.0	791.0	791.0	Detection of specific sequences among DNA fragments separated by gel electrophoresis.	E M Southern	J Mol Biol	1975	1195397	Yes
10	30236	30236.0	923.1	923.1	The assessment and analysis of handedness: the Edinburgh inventory.	R C Oldfield	Neuropsychologia	1971	5146491	Yes
11	29538	29538.0	686.0	686.0	MicroRNAs: genomics, biogenesis, mechanism, and function.	David P Bartel	Cell	2004	14744438	No
12	28459	28459.0	0.0	0.0	A rating scale for depression.	M Hamilton	J Neurol Neurosurg Psychiatry	1960	14399272	Yes
13	27240	27240.0	682.6	682.6	A new mathematical model for relative quantification in real-time RT-PCR.	M W Pfaffl	Nucleic Acids Res	2001	11328886	Yes
14	26310	26310.0	849.7	849.7	Confidence Limits On Phylogenies: An Approach Using The Bootstrap.	Joseph Felsenstein	Evolution	1985	28561359	Yes
15	25520	25520.0	718.2	718.2	Projector augmented-wave method.	P E Blochl	Phys Rev B Condens Matter	1994	9976227	Yes
16	50098	25049.0	1541.5	770.8	Hallmarks of cancer: the next generation.	Douglas Hanahan, Robert A Weinberg	Cell	2011	21376230	No
17	72414	24138.0	2589.3	863.1	Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2.	Michael I Love, Wolfgang Huber, Simon Anders	Genome Biol	2014	25516281	Yes
18	71877	23959.0	2568.1	856.0	"Mini-mental state". A practical method for grading the cognitive state of patients for the clinician.	M F Folstein, S E Folstein, P R McHugh	J Psychiatr Res	1975	1202204	Yes
19	22636	22636.0	785.2	785.2	Density-functional exchange-energy approximation with correct asymptotic behavior.	A D Becke	Phys Rev A Gen Phys	1988	9900728	Yes
20	66581	22193.7	1626.7	542.2	DNA sequencing with chain-terminating inhibitors.	F Sanger, S Nicklen, A R Coulson	Proc Natl Acad Sci U S A	1977	271968	Yes
21	42746	21373.0	1374.6	687.3	The neighbor-joining method: a new method for reconstructing phylogenetic trees.	N Saitou, M Nei	Mol Biol Evol	1987	3447015	Yes
22	21079	21079.0	844.8	844.8	RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies.	Alexandros Stamatakis	Bioinformatics	2014	24451623	Yes
23	42111	21055.5	1309.6	654.8	Fast gapped-read alignment with Bowtie 2.	Ben Langmead, Steven L Salzberg	Nat Methods	2012	22388286	Yes
24	20946	20946.0	0.0	0.0	Tissue sulfhydryl groups.	G L Ellman	Arch Biochem Biophys	1959	13650640	Yes
25	41715	20857.5	1661.4	830.7	The measurement of observer agreement for categorical data.	J R Landis, G G Koch	Biometrics	1977	843571	Yes
26	20568	20568.0	0.0	0.0	The use of lead citrate at high pH as an electron-opaque stain in electron microscopy.	E S Reynolds	J Cell Biol	1963	13986422	Yes
27	61591	20530.3	1894.3	631.4	Generalized Gradient Approximation Made Simple.	J P Perdew, K Burke, M Ernzerhof	Phys Rev Lett	1996	10062328	Yes
28	38672	19336.0	1863.8	931.9	Statistical methods for assessing agreement between two methods of clinical measurement.	J M Bland, D G Altman	Lancet	1986	2868172	Yes
29	38536	19268.0	999.1	499.6	Fast and accurate short read alignment with Burrows-Wheeler transform.	Heng Li, Richard Durbin	Bioinformatics	2009	19451168	Yes
30	19100	19100.0	862.8	862.8	A power primer.	J Cohen	Psychol Bull	1992	19565683	Yes
31	18965	18965.0	646.7	646.7	A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences.	M Kimura	J Mol Evol	1980	7463489	Yes
32	18518	18518.0	865.8	865.8	Crystal structure refinement with SHELXL.	George M Sheldrick	Acta Crystallogr C Struct Chem	2015	25567568	Yes
33	53746	17915.3	1604.7	534.9	Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.	H Towbin, T Staehelin, J Gordon	Proc Natl Acad Sci U S A	1979	388439	Yes
34	35105	17552.5	1430.5	715.2	The hospital anxiety and depression scale.	A S Zigmond, R P Snaith	Acta Psychiatr Scand	1983	6880820	Yes
35	17507	17507.0	477.4	477.4	Atherosclerosis--an inflammatory disease.	R Ross	N Engl J Med	1999	9887164	No
36	34787	17393.5	977.9	488.9	Efficient iterative schemes for ab initio total-energy calculations using a plane-wave basis set.	G Kresse, J Furthmuller	Phys Rev B Condens Matter	1996	9984901	Yes
37	17050	17050.0	676.6	676.6	Catalase in vitro.	H Aebi	Methods Enzymol	1984	6727660	Yes
38	33950	16975.0	0.0	0.0	A rapid method of total lipid extraction and purification.	E G Bligh, W J Dyer	Can J Biochem Physiol	1959	13671378	Yes
39	16784	16784.0	0.0	0.0	Disc Electrophoresis. Ii. Method And Application To Human Serum Proteins.	B J Davis	Ann N Y Acad Sci	1964	14240539	Yes
40	33441	16720.5	1288.7	644.4	Meta-analysis in clinical trials.	R DerSimonian, N Laird	Control Clin Trials	1986	3802833	Yes
41	16535	16535.0	423.0	423.0	MicroRNAs: target recognition and regulatory functions.	David P Bartel	Cell	2009	19167326	No
42	16248	16248.0	433.2	433.2	High resolution two-dimensional electrophoresis of proteins.	P H O'Farrell	J Biol Chem	1975	236308	Yes
43	16076	16076.0	625.0	625.0	Investigation of the freely available easy-to-use software 'EZR' for medical statistics.	Y Kanda	Bone Marrow Transplant	2013	23208313	Yes
44	47878	15959.3	1771.6	590.5	Trimmomatic: a flexible trimmer for Illumina sequence data.	Anthony M Bolger, Marc Lohse, Bjoern Usadel	Bioinformatics	2014	24695404	Yes
45	15948	15948.0	0.0	0.0	A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid.	K Burton	Biochem J	1956	13293190	Yes
46	46988	15662.7	1412.8	470.9	CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.	J D Thompson, D G Higgins, T J Gibson	Nucleic Acids Res	1994	7984417	Yes
47	30548	15274.0	1135.8	567.9	MAFFT multiple sequence alignment software version 7: improvements in performance and usability.	Kazutaka Katoh, Daron M Standley	Mol Biol Evol	2013	23329690	Yes
48	15051	15051.0	538.5	538.5	Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses.	Andreas Stang	Eur J Epidemiol	2010	20652370	Yes
49	14679	14679.0	374.8	374.8	Xds.	Wolfgang Kabsch	Acta Crystallogr D Biol Crystallogr	2010	20124692	Yes
50	14655	14655.0	623.8	623.8	Prokka: rapid prokaryotic genome annotation.	Torsten Seemann	Bioinformatics	2014	24642063	Yes
51	43766	14588.7	0.0	0.0	A simple method for the isolation and purification of total lipides from animal tissues.	J Folch, M Lees, G H Sloane Stanley	J Biol Chem	1957	13428781	Yes
52	29138	14569.0	907.5	453.8	Quantifying heterogeneity in a meta-analysis.	Julian P T Higgins, Simon G Thompson	Stat Med	2002	12111919	Yes
53	14356	14356.0	633.4	633.4	Self-efficacy: toward a unifying theory of behavioral change.	A Bandura	Psychol Rev	1977	847061	Yes
54	28591	14295.5	666.4	333.2	KEGG: kyoto encyclopedia of genes and genomes.	M Kanehisa, S Goto	Nucleic Acids Res	2000	10592173	Yes
55	28404	14202.0	603.4	301.7	Coot: model-building tools for molecular graphics.	Paul Emsley, Kevin Cowtan	Acta Crystallogr D Biol Crystallogr	2004	15572765	Yes
56	70522	14104.4	2096.1	419.2	Basic local alignment search tool.	S F Altschul, W Gish, W Miller, E W Myers, D J Lipman	J Mol Biol	1990	2231712	Yes
57	13883	13883.0	449.0	449.0	Search and clustering orders of magnitude faster than BLAST.	Robert C Edgar	Bioinformatics	2010	20709691	Yes
58	13780	13780.0	457.6	457.6	The Psychophysics Toolbox.	D H Brainard	Spat Vis	1997	9176952	Yes
59	41183	13727.7	1119.3	373.1	VMD: visual molecular dynamics.	W Humphrey, A Dalke, K Schulten	J Mol Graph	1996	8744570	Yes
60	40978	13659.3	1454.4	484.8	Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density.	C Lee, W Yang, R G Parr	Phys Rev B Condens Matter	1988	9944570	Yes
61	27156	13578.0	1203.1	601.5	The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection.	J E Ware, C D Sherbourne	Med Care	1992	1593914	Yes
62	40561	13520.3	1345.8	448.6	NIH Image to ImageJ: 25 years of image analysis.	Caroline A Schneider, Wayne S Rasband, Kevin W Eliceiri	Nat Methods	2012	22930834	No
63	13413	13413.0	226.8	226.8	The genetics of Caenorhabditis elegans.	S Brenner	Genetics	1974	4366476	Yes
64	12983	12983.0	438.6	438.6	Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS).	J F Kurtzke	Neurology	1983	6685237	Yes
65	12801	12801.0	511.7	511.7	A new method for measuring daytime sleepiness: the Epworth sleepiness scale.	M W Johns	Sleep	1991	1798888	Yes
66	12787	12787.0	587.0	587.0	SHELXT - integrated space-group and crystal-structure determination.	George M Sheldrick	Acta Crystallogr A Found Adv	2015	25537383	Yes
67	12671	12671.0	0.0	0.0	Phosphorus assay in column chromatography.	G R Bartlett	J Biol Chem	1959	13641241	Yes
68	49957	12489.2	1617.6	404.4	Measuring inconsistency in meta-analyses.	Julian P T Higgins, Simon G Thompson, Jonathan J Deeks, Douglas G Altman	BMJ	2003	12958120	No
69	24631	12315.5	558.6	279.3	Processing of X-ray diffraction data collected in oscillation mode.	Z Otwinowski, W Minor	Methods Enzymol	1997	27754618	Yes
70	11649	11649.0	320.3	320.3	Semiempirical GGA-type density functional constructed with a long-range dispersion correction.	Stefan Grimme	J Comput Chem	2006	16955487	Yes
71	22906	11453.0	717.2	358.6	AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading.	Oleg Trott, Arthur J Olson	J Comput Chem	2010	19499576	Yes
72	22843	11421.5	982.2	491.1	The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations.	R M Baron, D A Kenny	J Pers Soc Psychol	1986	3806354	Yes
73	34174	11391.3	1144.6	381.5	The PHQ-9: validity of a brief depression severity measure.	K Kroenke, R L Spitzer, J B Williams	J Gen Intern Med	2001	11556941	Yes
74	11170	11170.0	0.0	0.0	On the origin of cancer cells.	O Warburg	Science	1956	13298683	Yes
75	10988	10988.0	385.3	385.3	Structure validation in chemical crystallography.	Anthony L Spek	Acta Crystallogr D Biol Crystallogr	2009	19171970	Yes
76	10986	10986.0	309.0	309.0	The blockade of immune checkpoints in cancer immunotherapy.	Drew M Pardoll	Nat Rev Cancer	2012	22437870	No
77	43653	10913.2	1569.6	392.4	Bias in meta-analysis detected by a simple, graphical test.	M Egger, G Davey Smith, M Schneider, C Minder	BMJ	1997	9310563	Yes
78	10891	10891.0	467.9	467.9	Psychophysical bases of perceived exertion.	G A Borg	Med Sci Sports Exerc	1982	7154893	Yes
79	43288	10822.0	1615.5	403.9	A new method of classifying prognostic comorbidity in longitudinal studies: development and validation.	M E Charlson, P Pompei, K L Ales, C R MacKenzie	J Chronic Dis	1987	3558716	Yes
80	32438	10812.7	870.3	290.1	edgeR: a Bioconductor package for differential expression analysis of digital gene expression data.	Mark D Robinson, Davis J McCarthy, Gordon K Smyth	Bioinformatics	2010	19910308	Yes
81	10802	10802.0	452.8	452.8	Minimap2: pairwise alignment for nucleotide sequences.	Heng Li	Bioinformatics	2018	29750242	Yes
82	21559	10779.5	570.7	285.4	A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.	A P Feinberg, B Vogelstein	Anal Biochem	1983	6312838	Yes
83	10578	10578.0	264.8	264.8	PAML 4: phylogenetic analysis by maximum likelihood.	Ziheng Yang	Mol Biol Evol	2007	17483113	Yes
84	10556	10556.0	301.0	301.0	Evolutionary trees from DNA sequences: a maximum likelihood approach.	J Felsenstein	J Mol Evol	1981	7288891	Yes
85	21029	10514.5	506.5	253.2	BEDTools: a flexible suite of utilities for comparing genomic features.	Aaron R Quinlan, Ira M Hall	Bioinformatics	2010	20110278	Yes
86	20807	10403.5	570.7	285.4	Analyzing real-time PCR data by the comparative C(T) method.	Thomas D Schmittgen, Kenneth J Livak	Nat Protoc	2008	18546601	Yes
87	10395	10395.0	273.7	273.7	Canonical dynamics: Equilibrium phase-space distributions.	W G Hoover	Phys Rev A Gen Phys	1985	9895674	Yes
88	10345	10345.0	418.1	418.1	UPARSE: highly accurate OTU sequences from microbial amplicon reads.	Robert C Edgar	Nat Methods	2013	23955772	Yes
89	10330	10330.0	222.1	222.1	Mfold web server for nucleic acid folding and hybridization prediction.	Michael Zuker	Nucleic Acids Res	2003	12824337	Yes
90	10318	10318.0	0.0	0.0	Improvements in epoxy resin embedding methods.	J H Luft	J Biophys Biochem Cytol	1961	13764136	Yes
91	20552	10276.0	1266.5	633.2	A Guideline of Selecting and Reporting Intraclass Correlation Coefficients for Reliability Research.	Terry K Koo, Mae Y Li	J Chiropr Med	2016	27330520	Yes
92	10133	10133.0	306.2	306.2	Vitamin D deficiency.	Michael F Holick	N Engl J Med	2007	17634462	No
93	30164	10054.7	1156.4	385.5	Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups.	Allison Tong, Peter Sainsbury, Jonathan Craig	Int J Qual Health Care	2007	17872937	Yes
94	20094	10047.0	495.0	247.5	WGCNA: an R package for weighted correlation network analysis.	Peter Langfelder, Steve Horvath	BMC Bioinformatics	2008	19114008	Yes
95	40053	10013.2	1435.1	358.8	G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences.	Franz Faul, Edgar Erdfelder, Albert-Georg Lang, Axel Buchner	Behav Res Methods	2007	17695343	Yes
96	9939	9939.0	271.4	271.4	Apoptosis: a review of programmed cell death.	Susan Elmore	Toxicol Pathol	2007	17562483	No
97	19829	9914.5	0.0	0.0	The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis.	K Weber, M Osborn	J Biol Chem	1969	5806584	Yes
98	19773	9886.5	508.9	254.4	A simple method for displaying the hydropathic character of a protein.	J Kyte, R F Doolittle	J Mol Biol	1982	7108955	Yes
99	9847	9847.0	0.0	0.0	Copper Enzymes In Isolated Chloroplasts. Polyphenoloxidase In Beta Vulgaris.	D I Arnon	Plant Physiol	1949	16654194	Yes
100	19691	9845.5	745.2	372.6	Three approaches to qualitative content analysis.	Hsiu-Fang Hsieh, Sarah E Shannon	Qual Health Res	2005	16204405	Yes
101	29450	9816.7	768.8	256.3	Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources.	Da Wei Huang, Brad T Sherman, Richard A Lempicki	Nat Protoc	2009	19131956	Yes
102	19583	9791.5	435.7	217.8	The hallmarks of cancer.	D Hanahan, R A Weinberg	Cell	2000	10647931	No
103	9776	9776.0	270.9	270.9	RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models.	Alexandros Stamatakis	Bioinformatics	2006	16928733	Yes
104	9725	9725.0	328.2	328.2	Banting lecture 1988. Role of insulin resistance in human disease.	G M Reaven	Diabetes	1988	3056758	No
105	9596	9596.0	259.8	259.8	Studies on transformation of Escherichia coli with plasmids.	D Hanahan	J Mol Biol	1983	6345791	Yes
106	47768	9553.6	1918.0	383.6	Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.	David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman,	PLoS Med	2009	19621072	No
107	19106	9553.0	436.1	218.1	Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.	Kazutoshi Takahashi, Shinya Yamanaka	Cell	2006	16904174	Yes
108	9517	9517.0	264.3	264.3	Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus.	M C Hochberg	Arthritis Rheum	1997	9324032	Yes
109	28492	9497.3	1442.7	480.9	MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets.	Sudhir Kumar, Glen Stecher, Koichiro Tamura	Mol Biol Evol	2016	27004904	Yes
110	9381	9381.0	292.7	292.7	AFNI: software for analysis and visualization of functional magnetic resonance neuroimages.	R W Cox	Comput Biomed Res	1996	8812068	Yes
111	9377	9377.0	0.0	0.0	The assessment of anxiety states by rating.	M Hamilton	Br J Med Psychol	1959	13638508	Yes
112	9252	9252.0	241.9	241.9	Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.	P S Thomas	Proc Natl Acad Sci U S A	1980	6159641	Yes
113	9247	9247.0	407.7	407.7	Interrater reliability: the kappa statistic.	Mary L McHugh	Biochem Med (Zagreb)	2012	23092060	Yes
114	9235	9235.0	272.5	272.5	The pathogenesis of atherosclerosis: a perspective for the 1990s.	R Ross	Nature	1993	8479518	No
115	27549	9183.0	958.4	319.5	Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey.	Daniel Dindo, Nicolas Demartines, Pierre-Alain Clavien	Ann Surg	2004	15273542	Yes
116	9161	9161.0	190.2	190.2	Linear models and empirical bayes methods for assessing differential expression in microarray experiments.	Gordon K Smyth	Stat Appl Genet Mol Biol	2004	16646809	Yes
117	9080	9080.0	242.9	242.9	Integrins: versatility, modulation, and signaling in cell adhesion.	R O Hynes	Cell	1992	1555235	No
118	8999	8999.0	445.5	445.5	Comparative fit indexes in structural models.	P M Bentler	Psychol Bull	1990	2320703	Yes
119	8978	8978.0	198.6	198.6	The functions of animal microRNAs.	Victor Ambros	Nature	2004	15372042	No
120	17534	8767.0	416.2	208.1	Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana.	S J Clough, A F Bent	Plant J	1998	10069079	Yes
121	8656	8656.0	292.2	292.2	An Introduction to Propensity Score Methods for Reducing the Effects of Confounding in Observational Studies.	Peter C Austin	Multivariate Behav Res	2011	21818162	Yes
122	8551	8551.0	336.4	336.4	The Strengths and Difficulties Questionnaire: a research note.	R Goodman	J Child Psychol Psychiatry	1997	9255702	Yes
123	8550	8550.0	240.5	240.5	Statistical method for testing the neutral mutation hypothesis by DNA polymorphism.	F Tajima	Genetics	1989	2513255	Yes
124	17081	8540.5	536.6	268.3	EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis.	Arnaud Delorme, Scott Makeig	J Neurosci Methods	2004	15102499	Yes
125	17025	8512.5	596.8	298.4	Multiwfn: a multifunctional wavefunction analyzer.	Tian Lu, Feiwu Chen	J Comput Chem	2012	22162017	Yes
126	8456	8456.0	231.6	231.6	Fast robust automated brain extraction.	Stephen M Smith	Hum Brain Mapp	2002	12391568	No
127	8453	8453.0	279.2	279.2	The Clinical Dementia Rating (CDR): current version and scoring rules.	J C Morris	Neurology	1993	8232972	Yes
128	16728	8364.0	460.9	230.4	RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome.	Bo Li, Colin N Dewey	BMC Bioinformatics	2011	21816040	Yes
129	16719	8359.5	469.1	234.6	Balanced basis sets of split valence, triple zeta valence and quadruple zeta valence quality for H to Rn: Design and assessment of accuracy.	Florian Weigend, Reinhart Ahlrichs	Phys Chem Chem Phys	2005	16240044	Yes
130	16585	8292.5	443.5	221.8	MrBayes 3: Bayesian phylogenetic inference under mixed models.	Fredrik Ronquist, John P Huelsenbeck	Bioinformatics	2003	12912839	Yes
131	8277	8277.0	237.5	237.5	A modified poisson regression approach to prospective studies with binary data.	Guangyong Zou	Am J Epidemiol	2004	15033648	Yes
132	8196	8196.0	178.0	178.0	Chromatin modifications and their function.	Tony Kouzarides	Cell	2007	17320507	No
133	8168	8168.0	0.0	0.0	Solvent content of protein crystals.	B W Matthews	J Mol Biol	1968	5700707	Yes
134	8123	8123.0	151.9	151.9	Tumor angiogenesis: therapeutic implications.	J Folkman	N Engl J Med	1971	4938153	No
135	8097	8097.0	273.0	273.0	Density-functional approximation for the correlation energy of the inhomogeneous electron gas.	J P Perdew	Phys Rev B Condens Matter	1986	9938299	Yes
136	7990	7990.0	264.8	264.8	The VideoToolbox software for visual psychophysics: transforming numbers into movies.	D G Pelli	Spat Vis	1997	9176953	Yes
137	7968	7968.0	221.0	221.0	"Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A.	W N Burnette	Anal Biochem	1981	6266278	Yes
138	7920	7920.0	226.3	226.3	A simplification of the protein assay method of Lowry et al. which is more generally applicable.	G L Peterson	Anal Biochem	1977	603028	Yes
139	23694	7898.0	692.7	230.9	Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.	W T Friedewald, R I Levy, D S Fredrickson	Clin Chem	1972	4337382	Yes
140	7800	7800.0	224.0	224.0	The role of protein kinase C in cell surface signal transduction and tumour promotion.	Y Nishizuka	Nature	1984	6232463	No
141	7751	7751.0	0.0	0.0	Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.	A Boyum	Scand J Clin Lab Invest Suppl	1968	4179068	Yes
142	7739	7739.0	212.0	212.0	Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.	J R Vane	Nat New Biol	1971	5284360	Yes
143	54029	7718.4	1487.0	212.4	Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.	S F Altschul, T L Madden, A A Schaffer, J Zhang, Z Zhang, W Miller, D J Lipman	Nucleic Acids Res	1997	9254694	No
144	7634	7634.0	0.0	0.0	Index for rating diagnostic tests.	W J Youden	Cancer	1950	15405679	Yes
145	7552	7552.0	265.4	265.4	Prejudice, social stress, and mental health in lesbian, gay, and bisexual populations: conceptual issues and research evidence.	Ilan H Meyer	Psychol Bull	2003	12956539	No
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